295 results on '"Workman, Creg J."'
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2. Aplp1 interacts with Lag3 to facilitate transmission of pathologic α-synuclein
3. LAG-3 and PD-1 synergize on CD8+ T cells to drive T cell exhaustion and hinder autocrine IFN-γ-dependent anti-tumor immunity
4. Blockade of LAG-3 and PD-1 leads to co-expression of cytotoxic and exhaustion gene modules in CD8+ T cells to promote antitumor immunity
5. LAG-3 as the third checkpoint inhibitor
6. IFNγ-induction of TH1-like regulatory T cells controls antiviral responses
7. Cutting Edge: LAG3 Dimerization Is Required for TCR/CD3 Interaction and Inhibition of Antitumor Immunity
8. Autoreactive CD8+ T cells are restrained by an exhaustion-like program that is maintained by LAG3
9. LAG3 associates with TCR–CD3 complexes and suppresses signaling by driving co-receptor–Lck dissociation
10. Neuronally expressed PDL1, not PD1, suppresses acute nociception
11. Therapeutic targeting of regulatory T cells in cancer
12. Interferon-γ: teammate or opponent in the tumour microenvironment?
13. Regulatory T Cells in the Tumor Microenvironment
14. Lymphocyte‐Activation Gene 3 Facilitates Pathological Tau Neuron‐to‐Neuron Transmission.
15. Neuropilin-1 is a T cell memory checkpoint limiting long-term antitumor immunity
16. Integrated BATF transcriptional network regulates suppressive intratumoral regulatory T cells
17. Adaptive plasticity of IL-10+ and IL-35+ Treg cells cooperatively promotes tumor T cell exhaustion
18. Pathological Tau transmission initiated by binding lymphocyte-activation gene 3
19. Data from Systemic Immune Dysfunction in Cancer Patients Driven by IL6 Induction of LAG3 in Peripheral CD8+ T Cells
20. Supplementary Data from Systemic Immune Dysfunction in Cancer Patients Driven by IL6 Induction of LAG3 in Peripheral CD8+ T Cells
21. Data from Immune Inhibitory Molecules LAG-3 and PD-1 Synergistically Regulate T-cell Function to Promote Tumoral Immune Escape
22. Supplementary Tables 1-2, Figures 1-11 from Immune Inhibitory Molecules LAG-3 and PD-1 Synergistically Regulate T-cell Function to Promote Tumoral Immune Escape
23. Pathological α-synuclein transmission initiated by binding lymphocyte-activation gene 3
24. Epitope Mapping of Therapeutic Antibodies Targeting Human LAG3
25. LAG3 limits regulatory T cell proliferation and function in autoimmune diabetes
26. Antibodies targeting conserved non-canonical antigens and endemic coronaviruses associate with favorable outcomes in severe COVID-19
27. Systemic Immune Dysfunction in Cancer Patients Driven by IL6 Induction of LAG3 in Peripheral CD8+ T Cells
28. Molecular Pathways and Mechanisms of LAG3 in Cancer Therapy
29. Interferon Gamma Induction of TH1-like Tregs Controls Anti-viral Responses
30. LAG-3, TGF-β, and cell-intrinsic PD-1 inhibitory pathways contribute to CD8 but not CD4 T-cell tolerance induced by allogeneic BMT with anti-CD40L
31. People critically ill with COVID-19 exhibit peripheral immune profiles predictive of mortality and reflective of SARS-CoV-2 lung viral burden
32. Interleukin-35: Structure, Function and Its Impact on Immune-Related Diseases
33. A Cre-driven allele-conditioning line to interrogate CD4+ conventional T cells
34. COVID-19 versus Non–COVID-19 Acute Respiratory Distress Syndrome: Comparison of Demographics, Physiologic Parameters, Inflammatory Biomarkers, and Clinical Outcomes
35. Stability and function of regulatory T cells is maintained by a neuropilin-1-semaphorin-4a axis
36. Interferon-γ: teammate or opponent in the tumour microenvironment?
37. The costimulatory activity of Tim-3 requires Akt and MAPK signaling and its recruitment to the immune synapse
38. Regulatory T Cells: Barriers of Immune Infiltration Into the Tumor Microenvironment
39. Aplp1 and the Aplp1-Lag3 Complex facilitates transmission of pathologic α-synuclein
40. The development and function of regulatory T cells
41. Bifurcated monocyte states are predictive of mortality in severe COVID-19
42. Competition for Active TGFβ Cytokine Allows for Selective Retention of Antigen-Specific Tissue- Resident Memory T Cells in the Epidermal Niche
43. Regulatory T Cell–Derived TRAIL Is Not Required for Peripheral Tolerance
44. The inhibitory cytokine IL-35 contributes to regulatory T-cell function
45. Correction of multi-gene deficiency in vivo using a single 'self-cleaving' 2A peptide–based retroviral vector
46. In Vivo Treg Suppression Assays
47. Modulation of Redox Balance Leaves Murine Diabetogenic TH1 T Cells “LAG-3-ing” Behind
48. Resistance to PD1 blockade in the absence of metalloprotease-mediated LAG3 shedding
49. Neuropilin-1: a checkpoint target with unique implications for cancer immunology and immunotherapy
50. Interferon gamma production by regulatory T cells is required for response to cancer immunotherapy
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