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5. Clinical features and management of individuals admitted to hospital with monkeypox and associated complications across the UK: a retrospective cohort study

Author

Dunning, Jake, Fink, Douglas L, Milligan, Iain D, Luintel, Akish, Rodger, Alison J, Bhagani, Sanjay R, Lamb, Lucy E, Moores, Rachel C, Lee, Simon F K, Brown, Colin S, Hopkins, Susan, Mepham, Stephen, Warren, Simon, Molloy, Aoife, Cropley, Ian, Kew, Alex, Karunaharan, Natasha, Scobie, Antonia, Hart, Jennifer, Irish, Dianne, Haque, Tanzina, Jalal, Hamid, Smith, Robin, Mack, Damien, Barber, Tristan, Burns, Fiona, Miller, Robert, Hamlyn, Eleanor, Simoes, Pedro, Athan, Breda, Abrahamsen, Jennifer, Joyce, Jessica, Taylor, Caroline, Reddecliffe, Sally, Miller, Chloe, Reeve, Brooke, Kingston, Hugh, Crocker-Buque, Tim, Massie, Nicolas, Dhariwal, Ankush, Jayakumar, Angelina, Hammond, Robert, Bramley, Alexandra, Kanitkar, Tanmay, Maynard-Smith, Laura, Gil, Eliza, O'Connor, Cavan, Cocker, Derek, Spicer, Wendy, Lanzman, Marisa, Thacker, Meera, Anorson, Zoe O, Patel, Dharmesh, Williams, Alan, Houlihan, Catherine F, Wakerley, Dominic, Gordon, Claire N, Callaby, Helen, Bailey, Daniel J, Furneaux, Jenna, Bown, Abbie M, Truelove, Elizabeth J, Killip, Marian J, Jackson, David, Beetar-King, Tracy L B, Arnold, Ulrike M V, Strachan, Rhea M, Matthew, Jones, Matthew, Hannah J, Osborne, Jane C, Rampling, Tommy, Vipond, Richard, Gibney, Barry, Owen, Jodie, Bond, Helena, Beynon, Will, Hunter, Michael, McCorry, Louise, Emerson, Carol, Quah, Say, Todd, Suzanne, McCarty, Emma, Walker, Eoin, Feeney, Susan, Curran, Tanya, Li, Kathy, Mullan, JD, Jackson, Kate, Nelson, Peter, Lewis, Kevin, McNicol, Mark, Pratt, Marcus, Smith, Anna, Vos, Erin, Alsalemee, Fahad, O Leary, Daniel, Canny, John, McGinnity, Katherine, Culbert, Carly, McDowell, Conor, McQuillan, Cathy, Jeong, Eunjin, Glass, Lynsey, Dyche, Jessica, McClean, Paula, Stewart, Rebecca, Ursolino, Harold, Perry, Melissa, McCormick, Hannah, Lim, Eleanor Y, Gkrania-Klotsas, Effrossyni, Bracchi, Margherita, Heskin, Joseph, Brown, Nicklas, Juniper, Thomas, Mora-Peris, Borja, Dalla-Pria, Alessia, Mackie, Nicola, Garvey, Lucy, Winston, Alan, Cooke, Graham, Nelson, Mark, Kilbride, Emer, Elbishi, Ala, Kerrigan, William, Silva, Joshua, Gohil, Jesal, Payagala, Sasha, Walters, Yasmin, Smith, Joanna, Goodfellow, Jonathan, Lyons, Kitty, Tung, Hsiu, Patel, Kinjal, Henderson, Merle, Butler, Michael, Peres, Edu, Silva Carvalho, Taiana, Joly, Antoine, Dickinson, Molly, Moore, Luke S P, Mughal, Nabeela, Hughes, Stephen, Chitlangia, Shrada, Viramgana, Priyanka, Byrne, Ruth, Randell, Paul, Strangis, Luigi, Poveda, Nicola, Bovey, Deborah, Richardson, Poppy, Heaslip, Vivian, Higgs, Christopher, Boffito, Marta, Girometti, Nicolo, Whitlock, Gary, Tittle, Victoria, Jones, Rachel, Rayment, Michael, Scott, Christopher, Asboe, David, Pond, Marcus, Muir, David, Rathish, Balram, O'Hara, Geraldine, Abeywickrema, Movin, Bailey, Sarah-Lou, Boyd, Sara E, Da Silva Fontoura, Dayana, Daunt, Anna, Mason, Claire Y, Murphy, Jamie, Naidu, Vasanth V, Patel, Aatish, Pley, Caitlin, Redmore, Ethan, Sharrocks, Katherine, Snell, Luke B, Sundramoorthi, Rohan, Tam, Jerry C H, Brown, Aisling, Douthwaite, Sam, Goodman, Anna, Nebbia, Gaia, Newsholme, William, Price, Nicholas, Shaw, Emily, Salam, Alex, van Nispen tot Pannerden, Claire, Winslow, Helen, Bilinska, Julia, Keegan, Sarah, Coleman, Harry, Doctor, Jessica, Moini, Nasreen, Chilton, Daniella, Haidari, Golaleh, Simons, Rebecca, Kulasegaram, Rajababu, Larbalestier, Nick, Nori, Achyuta, Potter, Jack R, Tuudah, Cecilia, Wade, Paul, Travers, Alexandra, Dunford, Sarah, Greenwood, Joshua, Oledimmah, Georgina, Gyampo, Lesley, SA Pinto, Pedro, Muse, AbdulKadir, Parker, Zoe, Alexander, Charlotte, Khan, Alexander, Ajayi, Medinat, Baltazar, Abigail, Sharella, Davis, Hersi, Nasra, Nguyen, Thuy, Timbo, Rugiatu, Jalloh, Ismail, Bryan, Susan, Clarke, Patricia, Kerr, Marcia, Amedu, Fidelis, BohoBonaba, Maria, Haque, Sarah, Howson, Michelle, Tambilawan, Norbai, Yupanqui Estay, Soledad, Bangura, Hawanatu, Gideon, Tseday, Jerome-oboh, Damilola, Tetteh, Linda, Nwagu, Chioma, Agbaglah, Viwoalo, Narag, Nona, Zaveri, Mahima, Ni Luanaigh, Maedhbh, Keane, Peggy, Peters, Joanna R, Rimmer, Stephanie, Abbara, Aula, Dosekun, Olamide, Bolland, Mhairi, Stafford, Adam, Saleh, Dina, Sheridan, Rhianna, Davies, Ella, Sun, Kristi, Gilchrist, Mark, Kukadia, Priti, Embrahimsa, Muhammed, Chiu, Christopher, Taylor, Lauren, Short, Charlotte, Alagratnam, Jasmini, Jayaweera, Iresh, Gundugola, Kavitha, Payne, Lara V S, Mody, Nisha, Quinn, Killian, Nic Fhogartaigh, Caoimhe, Kaur, Nivenjit, Bholah, Salmaan, Kantha, Kajann, Youngs, Jonathan, Lampejo, Temi, Pitto, Nicholas, Lawrence, David S, Middleditch, Holly, Dominguez-Dominguez, Lourdes, Ratnappuli, Ayoma, Al-Hashimi, Sara, Oliveira, Amelia, Ottaway, Zoe, Mulka, Larissa, Hodgson, Bethany, Lewthwaite, Penny, Neary, Anne M, Downey, Michael R, Lucy, Danielle C, McCallum, Craig I, Beadsworth, Michael, Ratcliffe, Libuse, Fletcher, Tom E, Davies, Gerry, Wong, Nicholas, Aston, Stephen, Wingfield, Thomas E, Blanchard, Thomas, Hine, Paul, Lester, Rebecca, Woolley, Stephen D, Gould, Susie, Smith, Christopher, Abouyannis, Michael, Atomode, Abolaji, Cruise, James, Samual, Merna, Scott, Nicola, Srirathan, Vino, Lewis, Joseph, Richards, Lauren, Cummings, Mary-Ann, Gillan, Emily, Peers, Rebecca, Tickle, Amy, Keating, Grace, Chinyanda, Tendi, Sanchez, Mav, Harrison, Daniel, Hoyle, Metcalfe, Ben, Taylor, Jennifer, Johnson, Nicky, Kelle, Neil, McDowell, Kirsty, Richardson, Ian, Saguidan, Monette, Farmer, Nicky, Gillespie, Angella, Willoughby, Shay, Parker, Samantha, Avulan, Shamseena, Arif, Shazia, Marshall, Suzanne, Carlisle, David, Rezaei, Mohsen, Booth, Angela, Watts, Joanne, Tremarco, Lauren, Jeyanayagam, Priyanga, Ubochi, Odinaka, Vagianos, Daniel, Richardson, Mark, Jarvis, Anthony, Gow, Kyra, Walmsley, Jade, O'keefe, Adam, Smielewska, Anna, Hopkins, Mark, Balane, Fatima, Bradley, Sarah, Corrah, Tumena, Daquiz, Venus, Dugan, Christopher, Elliot, Joshua, Foley, Fiona, Friday, Dawn, Gamit, May, Garner, David, Gokani, Karishma, John, Laurence, Joseph, Deepa, Khan, Nuzhath, Mamuyac, Cherifer, McGregor, Alastair, McSorley, John, Parris, Victoria, Rubinstein, Luciana, Rycroft, Julian, Salinas, Kelcy, Salinas, Jason, Sebatian, Jency, Smith, Melanie, Tejero Garcia, Marina, Ume, Uchenna, Vicentine, Margarete, Wallis, Gabriel, Sturdy, Ann, Whittington, Ashley, Jacobs, Nathan, Johnson, Leann, Bonington, Alec, Uriel, Alison, Ustianowski, Andrew, Dancso, Balazs, Hogan, Celia, van Halsema, Clare, Vilar, F Javier, Devine, Karen, Ajdukiewicz, Katherine, Rajendran, Rajesh, Ghosh, Samit, Riste, Michael, Machin, Nicholas, Babu, Chitra, Ahmad, Shazaad, Obeng, Dorcas, Dave, Farnaz, Conolley, Gavin, Thompson, Joseph, Tickell-Painter, Maya, Chakravorty, Prasun, Pringle, Rachel, Zafar, Mohammad R, Lawrence, Sarah, Sanchez-Gonzalez, Amada, Fernandez, Cristina, Goodwin, Lynsey, Carey, David, Howarth-Maddison, Molly, Moody, Samuel, Upton, Rebecca, Apthorp, Christina, Murray, Charlotte, Salthouse, Kirstie, Nadeem, Sabah, Ridley, Grant, White, Francesca, Brown, Andrew, Lawless, Michael, Mohamed, Mohamed, Mulligan, Robert, Belfield, Amy, Brolly, Jacob, Calderon, Maria, Cheveau, James, Cullinan, Milo, Garrad, Sophie, Griffiths, Will, Ireland, Aidan, Ireland, Peter, Milne, Charlotte, Nwajiugo, Paul, Quartey, John, Ghavami-Kia, Bijan, Duncan, Chris, Evans, Adam, Hunter, Ewan, Price, Ashley, Schmid, Matthias, Schwab, Uli, Taha, Yusri, Payne, Brendan, Elliott, Ivo A M, Crowe, Stewart, Woodrow, Charles J, Karageorgopoulos, Drosos E, Davis, Peter J, Lord, Emily, Bannister, Oliver J, Dagens, Andrew B, Harrison, Thomas, Cole, Joby, Tunbridge, Anne, Choudry, Saher, Telfer, Adam, Jhibril, Ihsan, Atta, Syed N, Stone, Ben, Evans, Cariad, Ankcorn, Mike, Akili, Suha, Yavuz, Mehmet, Goodall, Vicky, Farrow, Sam, Mountford, Georgina, Cusack, Tomas-Paul, Beard, Kate, Sutton, Julian, Clark, Tristan, Mason, Annette, Vickers, Mike, Macallan, Derek, Bicanic, Tihana, Houston, Angela, Pope, Cassie, Tan, NgeeKeong, Ward, Christopher, Jones, Imogen, Banerjee, Rishi, Cohen, Jonathan, Emonts-le Clercq, Marieke, Porter, David, Riordan, Andrew, Sinha, Ruchi, Whittaker, Elizabeth, Beynon, William, Heskin, Jospeh, Milligan, Iain, Payne, Lara, AI Payne, Brendan, Elliott, Ivo AM, and Beard, Katie

Published
2023
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6. Safety, pharmacokinetics, and antimalarial activity of the novel triaminopyrimidine ZY-19489: a first-in-human, randomised, placebo-controlled, double-blind, single ascending dose study, pilot food-effect study, and volunteer infection study

Author

Barber, Bridget E, Fernandez, Melissa, Patel, Hardik Babubhai, Barcelo, Catalina, Woolley, Stephen D, Patel, Harilal, Llewellyn, Stacey, Abd-Rahman, Azrin N, Sharma, Sunil, Jain, Mukul, Ghoghari, Ashok, Di Resta, Ilaria, Fuchs, Aline, Deni, Ioanna, Yeo, Tomas, Mok, Sachel, Fidock, David A, Chalon, Stephan, Möhrle, Jörg J, Parmar, Deven, McCarthy, James S, and Kansagra, Kevinkumar

Published
2022
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7. Characterizing the pharmacological interaction of the antimalarial combination artefenomel-piperaquine in healthy volunteers with induced blood stagePlasmodium falciparum

Author

Abd-Rahman, Azrin N., primary, Kaschek, Daniel, additional, Kümmel, Anne, additional, Webster, Rebecca, additional, Potter, Adam J., additional, Odedra, Anand, additional, Woolley, Stephen D, additional, Llewellyn, Stacey, additional, Webb, Lachlan, additional, Marquart, Louise, additional, Chalon, Stephan, additional, El Gaaloul, Myriam, additional, McCarthy, James S., additional, Möhrle, Jörg J., additional, and Barber, Bridget E., additional

Published
2024
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8. Longitudinal changes in iron homeostasis in human experimental and clinical malaria

Author

Woolley, Stephen D, primary, Grigg, Matthew J, additional, Marquart, Louise, additional, Gower, Jeremy, additional, Piera, Kim, additional, Sheela Nair, Arya, additional, Amante, Fiona M, additional, Rajahram, Giri S, additional, William, Timothy, additional, Frazer, David M, additional, Chalon, Stephan, additional, McCarthy, James S, additional, Anstey, Nicholas M, additional, and Barber, Bridget E, additional

Published
2023
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13. Clinical features and management of individuals admitted to hospital with monkeypox and associated complications across the UK: a retrospective cohort study

Author

Fink, Douglas L, primary, Callaby, Helen, additional, Luintel, Akish, additional, Beynon, William, additional, Bond, Helena, additional, Lim, Eleanor Y, additional, Gkrania-Klotsas, Effrossyni, additional, Heskin, Jospeh, additional, Bracchi, Margherita, additional, Rathish, Balram, additional, Milligan, Iain, additional, O'Hara, Geraldine, additional, Rimmer, Stephanie, additional, Peters, Joanna R, additional, Payne, Lara, additional, Mody, Nisha, additional, Hodgson, Bethany, additional, Lewthwaite, Penny, additional, Lester, Rebecca, additional, Woolley, Stephen D, additional, Sturdy, Ann, additional, Whittington, Ashley, additional, Johnson, Leann, additional, Jacobs, Nathan, additional, Quartey, John, additional, AI Payne, Brendan, additional, Crowe, Stewart, additional, Elliott, Ivo AM, additional, Harrison, Thomas, additional, Cole, Joby, additional, Beard, Katie, additional, Cusack, Tomas-Paul, additional, Jones, Imogen, additional, Banerjee, Rishi, additional, Rampling, Tommy, additional, Dunning, Jake, additional, Fink, Douglas, additional, Rodger, Alison, additional, Bhagani, Sanjay, additional, Lamb, Lucy, additional, Moores, Rachel, additional, Lee, Simon, additional, Brown, Colin, additional, Hopkins, Susan, additional, Mepham, Stephen, additional, Warren, Simon, additional, Molloy, Aoife, additional, Cropley, Ian, additional, Kew, Alex, additional, Karunaharan, Natasha, additional, Scobie, Antonia, additional, Hart, Jennifer, additional, Irish, Dianne, additional, Haque, Tanzina, additional, Jalal, Hamid, additional, Smith, Robin, additional, Mack, Damien, additional, Barber, Tristan, additional, Burns, Fiona, additional, Miller, Robert, additional, Hamlyn, Eleanor, additional, Simoes, Pedro, additional, Athan, Breda, additional, Abrahamsen, Jennifer, additional, Joyce, Jessica, additional, Taylor, Caroline, additional, Reddecliffe, Sally, additional, Miller, Chloe, additional, Reeve, Brooke, additional, Kingston, Hugh, additional, Crocker-Buque, Tim, additional, Massie, Nicolas, additional, Dhariwal, Ankush, additional, Jayakumar, Angelina, additional, Hammond, Robert, additional, Bramley, Alexandra, additional, Kanitkar, Tanmay, additional, Maynard-Smith, Laura, additional, Gil, Eliza, additional, O'Connor, Cavan, additional, Cocker, Derek, additional, Spicer, Wendy, additional, Lanzman, Marisa, additional, Thacker, Meera, additional, Anorson, Zoe, additional, Patel, Dharmesh, additional, Williams, Alan, additional, Houlihan, Catherine, additional, Wakerley, Dominic, additional, Gordon, Claire, additional, Bailey, Daniel, additional, Furneaux, Jenna, additional, Bown, Abbie, additional, Truelove, Elizabeth, additional, Killip, Marian, additional, Jackson, David, additional, Beetar-King, Tracy, additional, Arnold, Ulrike, additional, Strachan, Rhea, additional, Matthew, Jones, additional, Matthew, Hannah, additional, Osborne, Jane, additional, Vipond, Richard, additional, Gibney, Barry, additional, Owen, Jodie, additional, Beynon, Will, additional, Hunter, Michael, additional, McCorry, Louise, additional, Emerson, Carol, additional, Quah, Say, additional, Todd, Suzanne, additional, McCarty, Emma, additional, Walker, Eoin, additional, Feeney, Susan, additional, Curran, Tanya, additional, Li, Kathy, additional, Mullan, JD, additional, Jackson, Kate, additional, Nelson, Peter, additional, Lewis, Kevin, additional, McNicol, Mark, additional, Pratt, Marcus, additional, Smith, Anna, additional, Vos, Erin, additional, Alsalemee, Fahad, additional, O Leary, Daniel, additional, Canny, John, additional, McGinnity, Katherine, additional, Culbert, Carly, additional, McDowell, Conor, additional, McQuillan, Cathy, additional, Jeong, Eunjin, additional, Glass, Lynsey, additional, Dyche, Jessica, additional, McClean, Paula, additional, Stewart, Rebecca, additional, Ursolino, Harold, additional, Perry, Melissa, additional, McCormick, Hannah, additional, Lim, Eleanor, additional, Heskin, Joseph, additional, Brown, Nicklas, additional, Juniper, Thomas, additional, Mora-Peris, Borja, additional, Dalla-Pria, Alessia, additional, Mackie, Nicola, additional, Garvey, Lucy, additional, Winston, Alan, additional, Cooke, Graham, additional, Nelson, Mark, additional, Kilbride, Emer, additional, Elbishi, Ala, additional, Kerrigan, William, additional, Silva, Joshua, additional, Gohil, Jesal, additional, Payagala, Sasha, additional, Walters, Yasmin, additional, Smith, Joanna, additional, Goodfellow, Jonathan, additional, Lyons, Kitty, additional, Tung, Hsiu, additional, Patel, Kinjal, additional, Henderson, Merle, additional, Butler, Michael, additional, Peres, Edu, additional, Silva Carvalho, Taiana, additional, Joly, Antoine, additional, Dickinson, Molly, additional, Moore, Luke, additional, Mughal, Nabeela, additional, Hughes, Stephen, additional, Chitlangia, Shrada, additional, Viramgana, Priyanka, additional, Byrne, Ruth, additional, Randell, Paul, additional, Strangis, Luigi, additional, Poveda, Nicola, additional, Bovey, Deborah, additional, Richardson, Poppy, additional, Heaslip, Vivian, additional, Higgs, Christopher, additional, Boffito, Marta, additional, Girometti, Nicolo, additional, Whitlock, Gary, additional, Tittle, Victoria, additional, Jones, Rachel, additional, Rayment, Michael, additional, Scott, Christopher, additional, Asboe, David, additional, Pond, Marcus, additional, Muir, David, additional, Abeywickrema, Movin, additional, Bailey, Sarah-Lou, additional, Boyd, Sara, additional, Da Silva Fontoura, Dayana, additional, Daunt, Anna, additional, Mason, Claire, additional, Murphy, Jamie, additional, Naidu, Vasanth, additional, Patel, Aatish, additional, Pley, Caitlin, additional, Redmore, Ethan, additional, Sharrocks, Katherine, additional, Snell, Luke, additional, Sundramoorthi, Rohan, additional, Tam, Jerry, additional, Brown, Aisling, additional, Douthwaite, Sam, additional, Goodman, Anna, additional, Nebbia, Gaia, additional, Newsholme, William, additional, Price, Nicholas, additional, Shaw, Emily, additional, Salam, Alex, additional, van Nispen tot Pannerden, Claire, additional, Winslow, Helen, additional, Bilinska, Julia, additional, Keegan, Sarah, additional, Coleman, Harry, additional, Doctor, Jessica, additional, Moini, Nasreen, additional, Chilton, Daniella, additional, Haidari, Golaleh, additional, Simons, Rebecca, additional, Kulasegaram, Rajababu, additional, Larbalestier, Nick, additional, Nori, Achyuta, additional, Potter, Jack, additional, Tuudah, Cecilia, additional, Wade, Paul, additional, Travers, Alexandra, additional, Dunford, Sarah, additional, Greenwood, Joshua, additional, Oledimmah, Georgina, additional, Gyampo, Lesley, additional, SA Pinto, Pedro, additional, Muse, AbdulKadir, additional, Parker, Zoe, additional, Alexander, Charlotte, additional, Khan, Alexander, additional, Ajayi, Medinat, additional, Baltazar, Abigail, additional, Sharella, Davis, additional, Hersi, Nasra, additional, Nguyen, Thuy, additional, Timbo, Rugiatu, additional, Jalloh, Ismail, additional, Bryan, Susan, additional, Clarke, Patricia, additional, Kerr, Marcia, additional, Amedu, Fidelis, additional, BohoBonaba, Maria, additional, Haque, Sarah, additional, Howson, Michelle, additional, Tambilawan, Norbai, additional, Yupanqui Estay, Soledad, additional, Bangura, Hawanatu, additional, Gideon, Tseday, additional, Jerome-oboh, Damilola, additional, Tetteh, Linda, additional, Nwagu, Chioma, additional, Agbaglah, Viwoalo, additional, Narag, Nona, additional, Zaveri, Mahima, additional, Ni Luanaigh, Maedhbh, additional, Keane, Peggy, additional, Peters, Joanna, additional, Abbara, Aula, additional, Dosekun, Olamide, additional, Bolland, Mhairi, additional, Stafford, Adam, additional, Saleh, Dina, additional, Sheridan, Rhianna, additional, Davies, Ella, additional, Sun, Kristi, additional, Gilchrist, Mark, additional, Kukadia, Priti, additional, Embrahimsa, Muhammed, additional, Chiu, Christopher, additional, Taylor, Lauren, additional, Short, Charlotte, additional, Alagratnam, Jasmini, additional, Jayaweera, Iresh, additional, Gundugola, Kavitha, additional, Quinn, Killian, additional, Nic Fhogartaigh, Caoimhe, additional, Kaur, Nivenjit, additional, Bholah, Salmaan, additional, Kantha, Kajann, additional, Youngs, Jonathan, additional, Lampejo, Temi, additional, Pitto, Nicholas, additional, Lawrence, David, additional, Middleditch, Holly, additional, Dominguez-Dominguez, Lourdes, additional, Ratnappuli, Ayoma, additional, Al-Hashimi, Sara, additional, Oliveira, Amelia, additional, Ottaway, Zoe, additional, Mulka, Larissa, additional, Neary, Anne, additional, Downey, Michael, additional, Lucy, Danielle, additional, McCallum, Craig, additional, Beadsworth, Michael, additional, Ratcliffe, Libuse, additional, Fletcher, Tom, additional, Davies, Gerry, additional, Wong, Nicholas, additional, Aston, Stephen, additional, Wingfield, Thomas, additional, Blanchard, Thomas, additional, Hine, Paul, additional, Woolley, Stephen, additional, Gould, Susie, additional, Smith, Christopher, additional, Abouyannis, Michael, additional, Atomode, Abolaji, additional, Cruise, James, additional, Samual, Merna, additional, Scott, Nicola, additional, Srirathan, Vino, additional, Lewis, Joseph, additional, Richards, Lauren, additional, Cummings, Mary-Ann, additional, Gillan, Emily, additional, Peers, Rebecca, additional, Tickle, Amy, additional, Keating, Grace, additional, Chinyanda, Tendi, additional, Sanchez, Mav, additional, Harrison, Daniel, additional, Hoyle, Marie-Claire, additional, Metcalfe, Ben, additional, Taylor, Jennifer, additional, Johnson, Nicky, additional, Kelle, Neil, additional, McDowell, Kirsty, additional, Richardson, Ian, additional, Saguidan, Monette, additional, Farmer, Nicky, additional, Gillespie, Angella, additional, Willoughby, Shay, additional, Parker, Samantha, additional, Avulan, Shamseena, additional, Arif, Shazia, additional, Marshall, Suzanne, additional, Carlisle, David, additional, Rezaei, Mohsen, additional, Booth, Angela, additional, Watts, Joanne, additional, Tremarco, Lauren, additional, Jeyanayagam, Priyanga, additional, Ubochi, Odinaka, additional, Vagianos, Daniel, additional, Richardson, Mark, additional, Jarvis, Anthony, additional, Gow, Kyra, additional, Walmsley, Jade, additional, O'keefe, Adam, additional, Smielewska, Anna, additional, Hopkins, Mark, additional, Balane, Fatima, additional, Bradley, Sarah, additional, Corrah, Tumena, additional, Daquiz, Venus, additional, Dugan, Christopher, additional, Elliot, Joshua, additional, Foley, Fiona, additional, Friday, Dawn, additional, Gamit, May, additional, Garner, David, additional, Gokani, Karishma, additional, John, Laurence, additional, Joseph, Deepa, additional, Khan, Nuzhath, additional, Mamuyac, Cherifer, additional, McGregor, Alastair, additional, McSorley, John, additional, Papineni, Padmasayee, additional, Parris, Victoria, additional, Rubinstein, Luciana, additional, Rycroft, Julian, additional, Salinas, Kelcy, additional, Salinas, Jason, additional, Sebatian, Jency, additional, Smith, Melanie, additional, Tejero Garcia, Marina, additional, Ume, Uchenna, additional, Vicentine, Margarete, additional, Wallis, Gabriel, additional, Bonington, Alec, additional, Uriel, Alison, additional, Ustianowski, Andrew, additional, Dancso, Balazs, additional, Hogan, Celia, additional, van Halsema, Clare, additional, Vilar, F Javier, additional, Devine, Karen, additional, Ajdukiewicz, Katherine, additional, Rajendran, Rajesh, additional, Ghosh, Samit, additional, Riste, Michael, additional, Machin, Nicholas, additional, Babu, Chitra, additional, Ahmad, Shazaad, additional, Obeng, Dorcas, additional, Dave, Farnaz, additional, Conolley, Gavin, additional, Thompson, Joseph, additional, Tickell-Painter, Maya, additional, Chakravorty, Prasun, additional, Pringle, Rachel, additional, Zafar, Mohammad, additional, Lawrence, Sarah, additional, Sanchez-Gonzalez, Amada, additional, Fernandez, Cristina, additional, Dawson, Lynsey, additional, Carey, David, additional, Howarth-Maddison, Molly, additional, Moody, Samuel, additional, Upton, Rebecca, additional, Apthorp, Christina, additional, Murray, Charlotte, additional, Salthouse, Kirstie, additional, Nadeem, Sabah, additional, Ridley, Grant, additional, White, Francesca, additional, Brown, Andrew, additional, Lawless, Michael, additional, Mohamed, Mohamed, additional, Mulligan, Robert, additional, Belfield, Amy, additional, Brolly, Jacob, additional, Calderon, Maria, additional, Cheveau, James, additional, Cullinan, Milo, additional, Garrad, Sophie, additional, Griffiths, Will, additional, Ireland, Aidan, additional, Ireland, Peter, additional, Milne, Charlotte, additional, Nwajiugo, Paul, additional, Ghavami-Kia, Bijan, additional, Duncan, Chris, additional, Evans, Adam, additional, Hunter, Ewan, additional, Price, Ashley, additional, Schmid, Matthias, additional, Schwab, Uli, additional, Taha, Yusri, additional, Payne, Brendan, additional, Elliott, Ivo, additional, Woodrow, Charles, additional, Karageorgopoulos, Drosos, additional, Davis, Peter, additional, Lord, Emily, additional, Bannister, Oliver, additional, Dagens, Andrew, additional, Tunbridge, Anne, additional, Choudry, Saher, additional, Telfer, Adam, additional, Jhibril, Ihsan, additional, Atta, Syed, additional, Stone, Ben, additional, Evans, Cariad, additional, Ankcorn, Mike, additional, Akili, Suha, additional, Yavuz, Mehmet, additional, Goodall, Vicky, additional, Farrow, Sam, additional, Mountford, Georgina, additional, Beard, Kate, additional, Sutton, Julian, additional, Clark, Tristan, additional, Mason, Annette, additional, Vickers, Mike, additional, Macallan, Derek, additional, Bicanic, Tihana, additional, Houston, Angela, additional, Pope, Cassie, additional, Tan, NgeeKeong, additional, Ward, Christopher, additional, Cohen, Jonathan, additional, Emonts-le Clercq, Marieke, additional, Porter, David, additional, Riordan, Andrew, additional, Sinha, Ruchi, additional, and Whittaker, Elizabeth, additional

Published
2022
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15. Additional file 1 of Development and evaluation of a new Plasmodium falciparum 3D7 blood stage malaria cell bank for use in malaria volunteer infection studies

Author

Woolley, Stephen D., Fernandez, Melissa, Rebelo, Maria, Llewellyn, Stacey A., Marquart, Louise, Amante, Fiona H., Jennings, Helen E., Webster, Rebecca, Trenholme, Katharine, Chalon, Stephan, Joerg J. Moehrle, McCarthy, James S., and Barber, Bridget E.

Abstract

Additional file 1: Table S1. Schedule of events for both studies. Table S2. Growth parameters of the 3D7-MBE-008 pilot bank (n = 2) compared to 3D7 bank using historical data (n = 177). Table S3. Growth parameters of the 3D7-V1 pilot bank (n = 2) compared to 3D7-V2 bank using historical data (n = 177). Table S4. Overall clinical score recorded for each participant during 3D7-MBE-008 study. Table S5. Overall clinical score recorded for each participant during 3D7-V1 study.

Published
2021
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16. Development and evaluation of a new Plasmodium falciparum 3D7 blood stage malaria cell bank for use in malaria volunteer infection studies

Author

Woolley, Stephen D., primary, Fernandez, Melissa, additional, Rebelo, Maria, additional, Llewellyn, Stacey A., additional, Marquart, Louise, additional, Amante, Fiona H., additional, Jennings, Helen E., additional, Webster, Rebecca, additional, Trenholme, Katharine, additional, Chalon, Stephan, additional, Moehrle, Joerg J., additional, McCarthy, James S., additional, and Barber, Bridget E., additional

Published
2021
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17. Actinomyces europaeus Isolated from a Breast Abscess in a Penicillin-Allergic Patient

Author

White, Sarah E. and Woolley, Stephen D.

Subjects
Article Subject
Abstract

This is a case of Actinomyces europaeus in the breast abscess of a penicillin-allergic woman. The mainstay of treatment for actinomycosis is penicillin, and there is a lack of literature describing nonpenicillin treatment options. A 69-year-old woman presented acutely with a breast abscess which was managed with incision and drainage and antibiotic therapy to good response. 21 days after presentation, Actinomyces were grown from the culture of pus, so the patient was recalled and more rigorous treatment and follow-up were initiated. The penicillin allergy led to difficulty in the identification of an appropriate antimicrobial agent that was also logistically feasible to be given on an outpatient IV basis. IV tigecycline followed by oral clarithromycin was found to be effective treatment.

Published
2018
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22. Clinical features and management of individuals admitted to hospital with monkeypox and associated complications across the UK: a retrospective cohort study.

Author

Fink, Douglas L, Callaby, Helen, Luintel, Akish, Beynon, William, Bond, Helena, Lim, Eleanor Y, Gkrania-Klotsas, Effrossyni, Heskin, Jospeh, Bracchi, Margherita, Rathish, Balram, Milligan, Iain, O'Hara, Geraldine, Rimmer, Stephanie, Peters, Joanna R, Payne, Lara, Mody, Nisha, Hodgson, Bethany, Lewthwaite, Penny, Lester, Rebecca, and Woolley, Stephen D

Subjects
*MONKEYPOX, *BACTERIAL diseases, *COHORT analysis, *COMMUNICABLE diseases, *SYMPTOMS
Abstract

The scale of the 2022 global mpox (formerly known as monkeypox) outbreak has been unprecedented. In less than 6 months, non-endemic countries have reported more than 67 000 cases of a disease that had previously been rare outside of Africa. Mortality has been reported as rare but hospital admission has been relatively common. We aimed to describe the clinical and laboratory characteristics and outcomes of individuals admitted to hospital with mpox and associated complications, including tecovirimat recipients. In this cohort study, we undertook retrospective review of electronic clinical records and pathology data for all individuals admitted between May 6, and Aug 3, 2022, to 16 hospitals from the Specialist and High Consequence Infectious Diseases Network for Monkeypox. The hospitals were located in ten cities in England and Northern Ireland. Inclusion criteria were clinical signs consistent with mpox and MPXV DNA detected from at least one clinical sample by PCR testing. Patients admitted solely for isolation purposes were excluded from the study. Key outcomes included admission indication, complications (including pain, secondary infection, and mortality) and use of antibiotic and anti-viral treatments. Routine biochemistry, haematology, microbiology, and virology data were also collected. Outcomes were assessed in all patients with available data. 156 individuals were admitted to hospital with complicated mpox during the study period. 153 (98%) were male and three (2%) were female, with a median age of 35 years (IQR 30–44). Gender data were collected from electronic patient records, which encompassed full formal review of clincian notes. The prespecified options for data collection for gender were male, female, trans, non-binary, or unknown. 105 (71%) of 148 participants with available ethnicity data were of White ethnicity and 47 (30%) of 155 were living with HIV with a median CD4 count of 510 cells per mm3 (IQR 349–828). Rectal or perianal pain (including proctitis) was the most common indication for hospital admission (44 [28%] of 156). Severe pain was reported in 89 (57%) of 156, and secondary bacterial infection in 82 (58%) of 142 individuals with available data. Median admission duration was 5 days (IQR 2–9). Ten individuals required surgery and two cases of encephalitis were reported. 38 (24%) of the 156 individuals received tecovirimat with early cessation in four cases (two owing to hepatic transaminitis, one to rapid treatment response, and one to patient choice). No deaths occurred during the study period. Although life-threatening mpox appears rare in hospitalised populations during the current outbreak, severe mpox and associated complications can occur in immunocompetent individuals. Analgesia and management of superimposed bacterial infection are priorities for patients admitted to hospital. None. [ABSTRACT FROM AUTHOR]

Published
2023
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23. Longitudinal changes in iron homeostasis in human experimental and clinical malaria.

Author

Woolley SD, Grigg MJ, Marquart L, Gower J, Piera K, Nair AS, Amante FM, Rajahram GS, William T, Frazer DM, Chalon S, McCarthy JS, Anstey NM, and Barber BE

Abstract

Background: The interaction between iron deficiency and malaria is incompletely understood. We evaluated longitudinal changes in iron homeostasis in volunteers enrolled in malaria volunteer infection studies (VIS) and in Malaysian patients with falciparum and vivax malaria., Methods: We retrieved samples and associated data from 55 participants enrolled in malaria VIS, and 171 malaria patients and 30 healthy controls enrolled in clinical studies in Malaysia. Ferritin, hepcidin, erythropoietin, and soluble transferrin receptor (sTfR) were measured by ELISA., Results: In the VIS, participants' parasitaemia was correlated with baseline mean corpuscular volume (MCV), but not iron status (ferritin, hepcidin or sTfR). Ferritin, hepcidin and sTfR all increased during the VIS. Ferritin and hepcidin normalised by day 28, while sTfR remained elevated. In VIS participants, baseline iron status (ferritin) was associated with post-treatment increases in liver transaminase levels. In Malaysian malaria patients, hepcidin and ferritin were elevated on admission compared to healthy controls, while sTfR increased following admission. Hepcidin normalised by day 28; however, ferritin and sTfR both remained elevated 4 weeks following admission., Conclusion: Our findings demonstrate that parasitaemia is associated with an individual's MCV rather than iron status. The persistent elevation in sTfR 4 weeks post-infection in both malaria VIS and clinical malaria may reflect a causal link between malaria and iron deficiency., Competing Interests: Declaration of interests None of the authors have conflicts of interests to declare.

Published
2023
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