1. The Concise Guide To Pharmacology 2021/22: G Protein-Coupled Receptors
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Nigel J. M. Birdsall, Stephen J Lolait, Hans-Jürgen Wester, Paul L. Chazot, Sadashiva S. Karnik, Simon D. Harding, Celine Valant, Stephen P.H. Alexander, Olivier Civelli, Zsolt Csaba, Mastgugu Horiuchi, Khuraijam Dhanachandra Singh, Theodore L. Goodfriend, Morley D. Hollenberg, Duuamene Nyimanu, Shlomo Melmed, G. Enrico Rovati, Xavier Norel, Leigh A. Stoddart, Klemens Kaupmann, Robyn Macrae, Nicholas D. Holliday, Deborah L. Segaloff, Justo P. Castaño, Tony Ngo, Gordon Dent, Jean-Martin Beaulieu, Thomas L Williams, Antonia Cianciulli, Paweł Kozielewicz, Xaria X. Li, Jyrki P. Kukkonen, Craig A. McArdle, John D. Lee, Philippe Rondard, Steven D. Douglas, Hubert Vaudry, Khaled A. Al-Hosaini, Nan Chiang, Bernhard Bettler, Giovanni Tulipano, Corinne Bousquet, Karen J. Gregory, Craig Gerard, Robert T. Jensen, Stefan Schulz, Rithwik Ramachandran, Ross A. D. Bathgate, Deepa Jonnalagadda, David M. Thal, Takio Kitazawa, Manisha Ray, Bice Chini, Thomas Unger, Marta Fumagalli, Jean-Pierre Vilardaga, Donald T. Ward, Roger G. Pertwee, Stefan Offermanns, Marvin C. Gershengorn, Marc Parmentier, Pieter Timmermans, Eamonn Kelly, Yukihiko Sugimoto, Hamiyet Unal, Vincenzo Mitolo, Alistair Mathie, Emma L. Veale, Andrew L. Gundlach, Anthony P. Davenport, Mark T. Quinn, Jérôme Leprince, Christa E. Müller, Geoffrey Burnstock, Akos Heinemann, Jacqueline R. Kemp, Richard D. Ye, Bernard Mouillac, Roger J. Summers, Raul R. Gainetdinov, Girolamo Calò, Philip N. Murphy, Amelie Lupp, Kalyan C. Tirupula, Walter G. Thomas, Julien Hanson, Ahsan Husain, Katie Leach, Lucie H. Clapp, Hans Bräuner-Osborne, Gunnar Schulte, Kenneth E. Bernstein, Jean Mazella, Torsten Schöneberg, Satoru Eguchi, Martin C. Michel, Maria Antonietta Panaro, Kevin J. Catt, Rainer K. Reinscheid, Hans-Jürgen Kreienkamp, Wayne R. Alexander, Emanuel Escher, Anne Marie O'Carroll, Magnus Bäck, Laurence J. Miller, Jane F. Armstrong, Chiara Ruzza, Trent M. Woodruff, Daniel Hoyer, Chengcan Yao, Maria P. Abbracchio, John A. Peters, Gary B. Willars, Jean-Philippe Pin, David Vaudry, Debbie L. Hay, François Boulay, Davide Lecca, Eric R. Prossnitz, Arthur Christopoulos, Victoria A. Blaho, Yasuyuki Kihara, Charles Kennedy, Christopher Southan, László Hunyady, Pascal Dournaud, Fernand Gobeil, Cyril Goudet, Charles N. Serhan, Claes Dahlgren, Jörg Hamann, Tobias Langenhan, Ralf Jockers, Nicholas M. Barnes, Jean-Louis Nahon, Richard L. Hauger, Adam J. Pawson, Gareth J. Sanger, Tung Fong, Susan E. Leeman, Elena Faccenda, Edward J. Filardo, Valerie P. Tan, Marc de Gasparo, Ji Ming Wang, Jamie A. Davies, Jerold Chun, Stefania Ceruti, Tadashi Inagami, Réjean Couture, Kenneth A. Jacobson, Patrick Vanderheyden, Adriaan P. IJzerman, Janet J. Maguire, Christopher S. Walker, RS: CARIM other, Alexander, Stephen Ph [0000-0003-4417-497X], Christopoulos, Arthur [0000-0003-4442-3294], Davenport, Anthony P [0000-0002-2096-3117], Mathie, Alistair [0000-0001-6094-2890], Peters, John A [0000-0002-4277-4245], Veale, Emma L [0000-0002-6778-9929], Armstrong, Jane F [0000-0002-0524-0260], Faccenda, Elena [0000-0001-9855-7103], Harding, Simon D [0000-0002-9262-8318], Pawson, Adam J [0000-0003-2280-845X], Southan, Christopher [0000-0001-9580-0446], Davies, Jamie A [0000-0001-6660-4032], Abbracchio, Maria Pia [0000-0002-7833-3388], Bäck, Magnus [0000-0003-0853-5141], Bathgate, Ross [0000-0001-6301-861X], Beaulieu, Jean-Martin [0000-0002-0446-7447], Bettler, Bernhard [0000-0003-0842-8207], Blaho, Victoria [0000-0001-8499-2278], Bousquet, Corinne [0000-0002-2501-0593], Bräuner-Osborne, Hans [0000-0001-9495-7388], Burnstock, Geoffrey [0000-0001-8152-7979], Ceruti, Stefania [0000-0003-1663-4211], Chazot, Paul [0000-0002-5453-0379], Chiang, Nan [0000-0003-1963-1585], Chini, Bice [0000-0002-1686-284X], Chun, Jerold [0000-0003-3964-0921], Clapp, Lucie H [0000-0001-7802-4481], Dent, Gordon [0000-0001-9419-2952], Singh, Khuraijam Dhanachandra [0000-0003-0506-6896], Fumagalli, Marta [0000-0002-0158-842X], Gainetdinov, Raul R [0000-0003-2951-6038], Goudet, Cyril [0000-0002-8255-3535], Gregory, Karen J [0000-0002-3833-2137], Gundlach, Andrew L [0000-0002-6066-9692], Hamann, Jörg [0000-0002-9448-1727], Hanson, Julien [0000-0001-7063-7590], Hay, Debbie L [0000-0002-9558-5122], Heinemann, Akos [0000-0002-8554-2372], Holliday, Nicholas D [0000-0002-2900-828X], Hoyer, Daniel [0000-0002-1405-7089], IJzerman, Adriaan P [0000-0002-1182-2259], Jacobson, Kenneth A [0000-0001-8104-1493], Jockers, Ralf [0000-0002-4354-1750], Jonnalagadda, Deepa [0000-0002-1511-8197], Karnik, Sadashiva [0000-0003-0746-2753], Kaupmann, Klemens [0000-0001-8903-2508], Kennedy, Charles [0000-0001-9661-5437], Kihara, Yasuyuki [0000-0001-7462-3006], Kozielewicz, Pawel [0000-0003-1414-3566], Kukkonen, Jyrki P [0000-0002-6989-1564], Langenhan, Tobias [0000-0002-9061-3809], Leach, Katie [0000-0002-9280-1803], Lecca, Davide [0000-0002-3258-363X], Lee, John D [0000-0002-9976-7396], Leprince, Jérôme [0000-0002-7814-9927], Li, Xaria X [0000-0001-5924-2977], Lolait, Stephen J [0000-0001-7228-8072], Maguire, Janet [0000-0002-9254-7040], Mazella, Jean [0000-0002-5627-0742], McArdle, Craig A [0000-0003-4836-5351], Michel, Martin C [0000-0003-4161-8467], Miller, Laurence J [0000-0002-4554-3872], Mouillac, Bernard [0000-0002-3906-8673], Müller, Christa E [0000-0002-0013-6624], Nahon, Jean-Louis [0000-0001-9572-7779], Ngo, Tony [0000-0002-6779-2546], Norel, Xavier [0000-0003-0734-3359], O'Carroll, Anne-Marie [0000-0001-5255-8506], Offermanns, Stefan [0000-0001-8676-6805], Pertwee, Roger G [0000-0003-3227-2783], Pin, Jean-Philippe [0000-0002-1423-345X], Prossnitz, Eric R [0000-0001-9190-8302], Ramachandran, Rithwik [0000-0001-9557-9905], Ray, Manisha [0000-0002-8844-6191], Rondard, Philippe [0000-0003-1134-2738], Rovati, G Enrico [0000-0002-8788-9783], Ruzza, Chiara [0000-0003-1360-202X], Sanger, Gareth J [0000-0002-4231-1945], Schöneberg, Torsten [0000-0001-5313-0237], Schulte, Gunnar [0000-0002-2700-7013], Stoddart, Leigh A [0000-0002-4469-0600], Sugimoto, Yukihiko [0000-0001-6973-932X], Summers, Roger [0000-0002-8367-4056], Tan, Valerie P [0000-0002-7308-1601], Thal, David [0000-0002-0325-2524], Valant, Celine [0000-0002-2509-7465], Walker, Christopher S [0000-0001-8151-4123], Ward, Donald T [0000-0003-1342-9458], Woodruff, Trent M [0000-0003-1382-911X], Yao, Chengcan [0000-0003-3754-2842], Apollo - University of Cambridge Repository, Department of Pharmacology, and Experimental Immunology
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RM ,Cytoplasmic and Nuclear ,Computer science ,Databases, Pharmaceutical ,Humans ,Ion Channels ,Ligands ,Receptors, Cytoplasmic and Nuclear ,Receptors, G-Protein-Coupled ,Pharmacology ,IN-VITRO CHARACTERIZATION ,NO ,RS ,law.invention ,G-Protein-Coupled ,Databases ,03 medical and health sciences ,CALCIUM-SENSING RECEPTOR ,0302 clinical medicine ,DELTA-OPIOID RECEPTOR ,law ,Summary information ,Receptors ,HISTAMINE H-3 RECEPTOR ,FATTY-ACID RECEPTOR ,METABOTROPIC GLUTAMATE-RECEPTOR ,030304 developmental biology ,G protein-coupled receptor ,GONADOTROPIN-RELEASING-HORMONE ,0303 health sciences ,Clinical pharmacology ,FORMYL PEPTIDE RECEPTOR ,MUSCARINIC ACETYLCHOLINE-RECEPTOR ,3. Good health ,317 Pharmacy ,030220 oncology & carcinogenesis ,Pharmaceutical ,NEGATIVE ALLOSTERIC MODULATOR ,Catalytic receptors - Abstract
The Concise Guide to PHARMACOLOGY 2021/22 is the fifth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of nearly 1900 human drug targets with an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. Although the Concise Guide constitutes over 500 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point-in-time record that will survive database updates. The full contents of this section can be found at http://onlinelibrary.wiley.com/doi/bph.15538. G protein-coupled receptors are one of the six major pharmacological targets into which the Guide is divided, with the others being: ion channels, nuclear hormone receptors, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The landscape format of the Concise Guide is designed to facilitate comparison of related targets from material contemporary to mid-2021, and supersedes data presented in the 2019/20, 2017/18, 2015/16 and 2013/14 Concise Guides and previous Guides to Receptors and Channels. It is produced in close conjunction with the Nomenclature and Standards Committee of the International Union of Basic and Clinical Pharmacology (NC-IUPHAR), therefore, providing official IUPHAR classification and nomenclature for human drug targets, where appropriate.
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- 2021