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15 results on '"Wood, Mark L"'

1. Open Reduction and Cementation for Femoral Head Fracture Secondary to Avascular Necrosis: Preliminary Report

Author

Wood, Mark L, McDowell, Cathy M, Kerstetter, Tara L, and Kelley, Scott S

Subjects
musculoskeletal diseases, Adult, Male, Hip Fractures, Health Status, Bone Cements, Pain, Femur Head, Methylmethacrylate, Middle Aged, Severity of Illness Index, Article, Radiography, Fracture Fixation, Internal, Treatment Outcome, Femur Head Necrosis, Surveys and Questionnaires, Activities of Daily Living, Humans, Female, Follow-Up Studies
Abstract

Current treatment for femoral head avascular necrosis has shown good results in early stages of disease, but are not as impressive after progression to collapse. We treated 19 patients (20 hips) with Stage III avascular necrosis (AVN) by open reduction augmented by methylmethacrylate cementation. Follow up ranges from 6 months to 2 years (average=8.7 months). We followed patient progress with pre- and post-operative Harris Hip Scores, Womac Osteoarthritis Index and a Health Status Questionnaire (SF36). All patients realized immediate post-operative pain relief and improvement in function. Harris Hip, Womac Osteoarthritis Index and SF36 physical health scores improved significantly from 54.0 to 79.5 (p

Published
2000

14. Minimally invasive subcutaneous fasciotomy for chronic exertional compartment syndrome of the lower extremity.

Author

Wood ML and Almekinders LC

Subjects
Chronic Disease, Humans, Minimally Invasive Surgical Procedures instrumentation, Sports, Compartment Syndromes surgery, Fasciotomy, Lower Extremity surgery, Minimally Invasive Surgical Procedures methods, Physical Exertion
Abstract

Chronic exertional compartment syndrome of the lower extremity can be debilitating in the active population. Open fasciotomy typically provides a cure or significant improvement in up to 90% of patients, provided that the compartments are adequately released. Cosmetic deformity from the surgery may be a major concern, especially in the young female athlete. A technique for minimally invasive subcutaneous fasciotomy is described that allows adequate compartment release and a favorable cosmetic result.

Published
2004

15. Tendon creep is potentiated by NKISK and relaxin which produce collagen fiber sliding.

Author

Wood ML, Luthin WN, Lester GE, and Dahners LE

Subjects
Animals, Collagen metabolism, Decorin, Extracellular Matrix Proteins, Fibronectins metabolism, Guinea Pigs, In Vitro Techniques, Male, Models, Animal, Proteoglycans metabolism, Rats, Rats, Sprague-Dawley, Tendons metabolism, Collagen physiology, Movement physiology, Oligopeptides metabolism, Relaxin metabolism, Tendons physiology
Abstract

The pentapeptide NKISK has been reported to inhibit the binding of decorin, a proteoglycan on the surface of collagen fibrils, to fibronectin, a tissue adhesion molecule. Relaxin has been shown to be effective in relaxing ligaments and other connective tissues. Through collagen staining studies, we have previously demonstrated that collagen fiber sliding is important during changes in ligament length. Because of our interest in fibril-fibril binding as it relates to changes in length of tendon or ligament, we investigated the potential of NKISK, relaxin, or both in combination to potentiate creep. We suspended stained rat tail tendons in test solutions under a constant stress and observed length changes and subsequent collagen fiber sliding. Both NKISK and relaxin potentiated rat tail tendon creep with changes in length most likely occurring as a result of collagen fiber sliding as evidenced by photomicrography.

Published
2003

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