252 results on '"Wood, David K."'
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2. Stromal architecture directs early dissemination in pancreatic ductal adenocarcinoma
3. iCLOTS: open-source, artificial intelligence-enabled software for analyses of blood cells in microfluidic and microscopy-based assays
4. Genetic reversal of the globin switch concurrently modulates both fetal and sickle hemoglobin and reduces red cell sickling
5. JAK-STAT inhibition reduces endothelial prothrombotic activation and leukocyte–endothelial proadhesive interactions
6. Microfluidic methods to advance mechanistic understanding and translational research in sickle cell disease
7. An irradiated marrow niche reveals a small noncollagenous protein mediator of homing, dermatopontin
8. MetAP2 inhibition modifies hemoglobin S to delay polymerization and improves blood flow in sickle cell disease
9. An Experimental-Computational Approach to Quantify Blood Rheology in Sickle Cell Disease
10. High-throughput assessment of hemoglobin polymer in single red blood cells from sickle cell patients under controlled oxygen tension
11. Next generation microfluidics: fulfilling the promise of lab-on-a-chip technologies
12. CDK4/6 inhibition enhances SHP2 inhibitor efficacy and is dependent upon RB function in malignant peripheral nerve sheath tumors
13. Distant Relations: Macrophage Functions in the Metastatic Niche
14. SEMA4C is a novel target to limit osteosarcoma growth, progression, and metastasis
15. Extracellular fluid tonicity impacts sickle red blood cell deformability and adhesion
16. Ex vivo to in vivo model of malignant peripheral nerve sheath tumors for precision oncology
17. Robust microtubule dynamics facilitate low-tension kinetochore detachment in metaphase
18. Deoxygenation Reduces Sickle Cell Blood Flow at Arterial Oxygen Tension
19. High-throughput quantification of red blood cell deformability and oxygen saturation to probe mechanisms of sickle cell disease.
20. CDK4/6 inhibition enhances SHP2 inhibitor efficacy and is dependent upon restoration of RB function in malignant peripheral nerve sheath tumors
21. Point-of-care diagnostics for noncommunicable diseases using synthetic urinary biomarkers and paper microfluidics
22. Fluorescence Lifetime Measurement of Prefibrillar Sickle Hemoglobin Oligomers as a Platform for Drug Discovery in Sickle Cell Disease
23. Ex vivo to in vivo model of malignant peripheral nerve sheath tumors for precision oncology
24. Microsystems Models of Pathophysiology
25. Single cell trapping and DNA damage analysis using microwell arrays
26. Extracellular Vesicles Mediate the Intercellular Exchange of Nanoparticles
27. The effect of rigid cells on blood viscosity: linking rheology and sickle cell anemia
28. Feature tracking microfluidic analysis reveals differential roles of viscosity and friction in sickle cell blood
29. Simultaneous quantification of blood rheology and oxygen saturation to evaluate affinity-modifying therapies in sickle cell disease
30. A scalable 3D tissue culture pipeline to enable functional therapeutic screening for pulmonary fibrosis
31. Model-Predicted Clinical Factors Impacting Patient-Specific Response of Sickle Cells to Voxelotor in a Microfluidic Platform
32. Effects of BCL11A Shmir-Induced Post-Transcriptional Silencing on Hemoglobin Polymer Inhibition in Single Red Blood Cells at Physiologic Oxygen Tension
33. Visualizing Sickle Cell Disease Whole Blood Flow and Viscosity through Modifications to Hemoglobin Levels from a Simple Blood Transfusion
34. Multiscale Cues Drive Collective Cell Migration
35. Ionophore-mediated swelling of erythrocytes as a therapeutic mechanism in sickle cell disease
36. An irradiated marrow niche reveals a small non-collagenous protein mediator of homing, dermatopontin
37. Micropatterned comet assay enables high throughput and sensitive DNA damage quantification
38. GPCR‐mediated YAP/TAZ inactivation in fibroblasts via EPAC1/2, RAP2C, and MAP4K7
39. Extracellular vesicles mediate the intercellular exchange of nanoparticles
40. Stromal architecture directs early dissemination in pancreatic ductal adenocarcinoma
41. CometChip
42. Robust Pre-Clinical Results and Large-Scale Manufacturing Process for Edit-301: An Autologous Cell Therapy for the Potential Treatment of SCD
43. Ruxolitinib Reduces Endothelial Pro-Adhesive Interactions: Implications for JAK2V617+ MPN Thrombosis
44. Voxelotor Improves Sickle Red Blood Cell Flow Under Hypoxia in a Microfluidic Venule
45. Microscale Collagen and Fibroblast Interactions Enhance Primary Human Hepatocyte Functions in Three-Dimensional Models
46. 5‐(Hydroxymethyl)furfural restores low‐oxygen rheology of sickle trait bloodin vitro
47. A microfluidic platform for simultaneous quantification of oxygen-dependent viscosity and shear thinning in sickle cell blood
48. Microscale Collagen and Fibroblast Interactions Enhance Primary Human Hepatocyte Functions in 3-Dimensional Models
49. Validation of BCL11A As Therapeutic Target in Sickle Cell Disease: Results from the Adult Cohort of a Pilot/Feasibility Gene Therapy Trial Inducing Sustained Expression of Fetal Hemoglobin Using Post-Transcriptional Gene Silencing
50. MetAP2 Inhibition Modifies Hemoglobin S (HbS) to Delay Polymerization and Improve Blood Flow in Sickle Cell Disease
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