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1,522 results on '"Woo, Y. Joseph"'

10. Predicting post-operative right ventricular failure using video-based deep learning

Author

Shad, Rohan, Quach, Nicolas, Fong, Robyn, Kasinpila, Patpilai, Bowles, Cayley, Castro, Miguel, Guha, Ashrith, Suarez, Eddie, Jovinge, Stefan, Lee, Sangjin, Boeve, Theodore, Amsallem, Myriam, Tang, Xiu, Haddad, Francois, Shudo, Yasuhiro, Woo, Y. Joseph, Teuteberg, Jeffrey, Cunningham, John P., Langlotz, Curt P., and Hiesinger, William

Subjects
Computer Science - Computer Vision and Pattern Recognition, Computer Science - Artificial Intelligence
Abstract

Non-invasive and cost effective in nature, the echocardiogram allows for a comprehensive assessment of the cardiac musculature and valves. Despite progressive improvements over the decades, the rich temporally resolved data in echocardiography videos remain underutilized. Human reads of echocardiograms reduce the complex patterns of cardiac wall motion, to a small list of measurements of heart function. Furthermore, all modern echocardiography artificial intelligence (AI) systems are similarly limited by design - automating measurements of the same reductionist metrics rather than utilizing the wealth of data embedded within each echo study. This underutilization is most evident in situations where clinical decision making is guided by subjective assessments of disease acuity, and tools that predict disease onset within clinically actionable timeframes are unavailable. Predicting the likelihood of developing post-operative right ventricular failure (RV failure) in the setting of mechanical circulatory support is one such clinical example. To address this, we developed a novel video AI system trained to predict post-operative right ventricular failure (RV failure), using the full spatiotemporal density of information from pre-operative echocardiography scans. We achieve an AUC of 0.729, specificity of 52% at 80% sensitivity and 46% sensitivity at 80% specificity. Furthermore, we show that our ML system significantly outperforms a team of human experts tasked with predicting RV failure on independent clinical evaluation. Finally, the methods we describe are generalizable to any cardiac clinical decision support application where treatment or patient selection is guided by qualitative echocardiography assessments., Comment: 12 pages, 3 figures

Published
2021
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11. Large Animal Translational Validation of 3 Mitral Valve Repair Operations for Mitral Regurgitation Using a Mitral Valve Prolapse Model: A Comprehensive In Vivo Biomechanical Engineering Analysis

Author

Zhu, Yuanjia, Yajima, Shin, Park, Matthew H., Venkatesh, Akshay, Stark, Charles J., Tran, Nicholas A., Walsh, Sabrina K., Ethiraj, Sidarth, Wilkerson, Robert J., Lin, Luca E., Lee, Seung Hyun, Gates, Kate Y., Arthur, Justin D., Baker, Sam W., Mullis, Danielle M., Wu, Catherine A., Harima, Shun, Pokhrel, Bipul, Resuello, Dominique, Bergamasco, Hunter, Wu, Matthew A., Baccouche, Basil M., Pandya, Pearly K., Elde, Stefan, Wang, Hanjay, and Woo, Y. Joseph

Published
2024
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17. stratamatch: Prognostic ScoreStratification using a Pilot Design

Author

Aikens, Rachael C., Rigdon, Joseph, Lee, Justin, Baiocchi, Michael, Goldstone, Andrew B., Chiu, Peter, Woo, Y. Joseph, and Chen, Jonathan H.

Subjects
Statistics - Computation
Abstract

Optimal propensity score matching has emerged as one of the most ubiquitous approaches for causal inference studies on observational data; However, outstanding critiques of the statistical properties of propensity score matching have cast doubt on the statistical efficiency of this technique, and the poor scalability of optimal matching to large data sets makes this approach inconvenient if not infeasible for sample sizes that are increasingly commonplace in modern observational data. The stratamatch package provides implementation support and diagnostics for `stratified matching designs,' an approach which addresses both of these issues with optimal propensity score matching for large-sample observational studies. First, stratifying the data enables more computationally efficient matching of large data sets. Second, stratamatch implements a `pilot design' approach in order to stratify by a prognostic score, which may increase the precision of the effect estimate and increase power in sensitivity analyses of unmeasured confounding., Comment: 15 pages, 5 figures, submitted to The R Journal

Published
2020

19. 2022 ACC/AHA guideline for the diagnosis and management of aortic disease: A report of the American Heart Association/American College of Cardiology Joint Committee on Clinical Practice Guidelines

Author

Isselbacher, Eric M., Preventza, Ourania, Hamilton Black, James, III, Augoustides, John G., Beck, Adam W., Bolen, Michael A., Braverman, Alan C., Bray, Bruce E., Brown-Zimmerman, Maya M., Chen, Edward P., Collins, Tyrone J., DeAnda, Abe, Jr., Fanola, Christina L., Girardi, Leonard N., Hicks, Caitlin W., Hui, Dawn S., Schuyler Jones, William, Kalahasti, Vidyasagar, Kim, Karen M., Milewicz, Dianna M., Oderich, Gustavo S., Ogbechie, Laura, Promes, Susan B., Ross, Elsie Gyang, Schermerhorn, Marc L., Singleton Times, Sabrina, Tseng, Elaine E., Wang, Grace J., Woo, Y. Joseph, Faxon, David P., Upchurch, Gilbert R., Jr, Aday, Aaron W., Azizzadeh, Ali, Boisen, Michael, Hawkins, Beau, Kramer, Christopher M., Luc, Jessica G.Y., MacGillivray, Thomas E., Malaisrie, S. Christopher, Osteen, Kathryn, Patel, Himanshu J., Patel, Parag J., Popescu, Wanda M., Rodriguez, Evelio, Sorber, Rebecca, Tsao, Philip S., Santos Volgman, Annabelle, Beckman, Joshua A., Otto, Catherine M., O'Gara, Patrick T., Armbruster, Anastasia, Birtcher, Kim K., de las Fuentes, Lisa, Deswal, Anita, Dixon, Dave L., Gorenek, Bulent, Haynes, Norrisa, Hernandez, Adrian F., Joglar, José A., Jones, W. Schuyler, Mark, Daniel, Mukherjee, Debabrata, Palaniappan, Latha, Piano, Mariann R., Rab, Tanveer, Spatz, Erica S., and Tamis-Holland, Jacqueline E.

Published
2023
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34. 2022 ACC/AHA Guideline for the Diagnosis and Management of Aortic Disease: A Report of the American Heart Association/American College of Cardiology Joint Committee on Clinical Practice Guidelines

Author

Isselbacher, Eric M., Preventza, Ourania, Hamilton Black III, James, Augoustides, John G., Beck, Adam W., Bolen, Michael A., Braverman, Alan C., Bray, Bruce E., Brown-Zimmerman, Maya M., Chen, Edward P., Collins, Tyrone J., DeAnda, Abe, Jr., Fanola, Christina L., Girardi, Leonard N., Hicks, Caitlin W., Hui, Dawn S., Jones, William Schuyler, Kalahasti, Vidyasagar, Kim, Karen M., Milewicz, Dianna M., Oderich, Gustavo S., Ogbechie, Laura, Promes, Susan B., Ross, Elsie Gyang, Schermerhorn, Marc L., Times, Sabrina Singleton, Tseng, Elaine E., Wang, Grace J., and Woo, Y. Joseph

Published
2022
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36. Coronary Artery Bypass Surgery Without Saphenous Vein Grafting: JACC Review Topic of the Week

Author

Royse, Alistair, Ren, Justin, Royse, Colin, Tian, David H., Fremes, Stephen, Gaudino, Mario, Benedetto, Umberto, Woo, Y. Joseph, Goldstone, Andrew B., Davierwala, Piroze, Borger, Michael, Vallely, Michael, Reid, Christopher M., Rocha, Rodolfo, Glineur, David, Grau, Juan, Shaw, Richard, Paterson, Hugh, El-Ansary, Doa, Boggett, Stuart, Srivastav, Nilesh, Pawanis, Zulfayandi, Canty, David, and Bellomo, Rinaldo

Published
2022
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40. 2022 ACC/AHA/HFSA Guideline for the Management of Heart Failure

Author

Heidenreich, Paul A., Bozkurt, Biykem, Aguilar, David, Allen, Larry A., Byun, Joni J., Colvin, Monica M., Deswal, Anita, Drazner, Mark H., Dunlay, Shannon M., Evers, Linda R., Fang, James C., Fedson, Savitri E., Fonarow, Gregg C., Hayek, Salim S., Hernandez, Adrian F., Khazanie, Prateeti, Kittleson, Michelle M., Lee, Christopher S., Link, Mark S., Milano, Carmelo A., Nnacheta, Lorraine C., Sandhu, Alexander T., Stevenson, Lynne Warner, Vardeny, Orly, Vest, Amanda R., Yancy, Clyde W., Beckman, Joshua A., O'Gara, Patrick T., Al-Khatib, Sana M., Armbruster, Anastasia L., Birtcher, Kim K., Cigarroa, Joaquin E., de las Fuentes, Lisa, Dixon, Dave L., Fleisher, Lee A., Gentile, Federico, Goldberger, Zachary D., Gorenek, Bulent, Haynes, Norrisa, Hlatky, Mark A., Joglar, José A., Jones, W. Schuyler, Marine, Joseph E., Mark, Daniel B., Mukherjee, Debabrata, Palaniappan, Latha P., Piano, Mariann R., Rab, Tanveer, Spatz, Erica S., Tamis-Holland, Jacqueline E., Wijeysundera, Duminda N., and Woo, Y. Joseph

Published
2022
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47. Natural cardiac regeneration conserves native biaxial left ventricular biomechanics after myocardial infarction in neonatal rats

Author

Wang, Hanjay, Wisneski, Andrew, Imbrie-Moore, Annabel M., Paulsen, Michael J., Wang, Zhongjie, Xuan, Yue, Lopez Hernandez, Hector, Hironaka, Camille E., Lucian, Haley J., Shin, Hye Sook, Anilkumar, Shreya, Thakore, Akshara D., Farry, Justin M., Eskandari, Anahita, Williams, Kiah M., Grady, Frederick, Wu, Matthew A., Jung, Jinsuh, Stapleton, Lyndsay M., Steele, Amanda N., Zhu, Yuanjia, and Woo, Y. Joseph

Published
2022
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48. Outcomes According to Coronary Disease Complexity and Optimal Thresholds to Guide Revascularization Approach: FAME 3 Trial.

Author

Dawson, Luke P., Kobayashi, Yuhei, Zimmermann, Frederik M., Takahashi, Tatsunori, Wong, Christopher C., Theriault-Lauzier, Pascal, Pijls, Nico H.J., De Bruyne, Bernard, Yeung, Alan C., Woo, Y. Joseph, and Fearon, William F.

Abstract

Coronary disease complexity is commonly used to guide revascularization strategy in patients with multivessel disease (MVD). The aim of this study was to assess the interactive effects of coronary complexity on percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) outcomes and identify the optimal threshold at which PCI can be considered a reasonable option. A total of 1,444 of 1,500 patients with MVD from the FAME (Fractional Flow Reserve versus Angiography for Multi-vessel Evaluation) 3 randomized trial were included in the analysis (710 CABG vs 734 PCI). SYNTAX (Synergy Between PCI With Taxus and Cardiac Surgery) scores were transformed into restricted cubic splines, and logistic regression models were fitted, with multiplicative interaction terms for revascularization strategy. Optimal thresholds at which PCI is a reasonable alternative to CABG were determined on the basis of Cox regression model performance. The mean SYNTAX score (SS) was 25.9 ± 7.1. SS was associated with 1-year major adverse cardiac and cerebrovascular events among PCI patients and 3-year death, myocardial infarction, and stroke among CABG patients. Significant interactions were present between revascularization strategy and SS for 1- and 3-year composite endpoints (P for interaction <0.05 for all). In Cox regression models, outcomes were comparable between CABG and PCI for the 3-year primary endpoint for SS ≤24 (P = 0.332), with 44% of patients below this threshold and 32% below the conventional SS threshold of ≤22. In patients with MVD without left main disease, PCI and CABG outcomes remain comparable up to SS values in the mid- rather than low 20s, which allows the identification of a greater proportion of patients in whom PCI may be a reasonable alternative to CABG. [Display omitted] [ABSTRACT FROM AUTHOR]

Published
2024
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