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2. Supplementary Methods, Figure Legends 1-6 from Ponatinib (AP24534), a Multitargeted Pan-FGFR Inhibitor with Activity in Multiple FGFR-Amplified or Mutated Cancer Models

4. SGX393 inhibits the CML mutant [Bcr-Abl.sup.T3151] and preempts in vitro resistance when combined with nilotinib or dasatinib

5. Activating alleles of JAK3 in acute megakaryoblastic leukemia

10. Potent Activity of Ponatinib (AP24534) in Models of FLT3-Driven Acute Myeloid Leukemia and Other Hematologic Malignancies

13. Abstract B259: Combined targeting of FGFR2 and mTOR by AP24534 and ridaforolimus results in synergistic antitumor activity in FGFR2‐driven endometrial cancer models

14. SGX393 inhibits the CML mutant Bcr-Abl T315I and preempts in vitro resistance when combined with nilotinib or dasatinib

15. SGX70393 Inhibits Bcr-AblT315I In Vitro and In Vivo and Completely Suppresses Resistance When Combined with Nilotinib or Dasatinib.

16. Inhibition of T315I Bcr-Abl and Other Imatinib-Resistant Bcr-Abl Mutants by the Selective Abl Kinase Inhibitor SGX70393.

17. In Chronic Myeloid Leukemia (CML) Patients with Complete Cytogenetic Response to Imatinib, BCR-ABL Kinase Domain Mutations Are Relatively Rare and Not Consistently Associated with Subsequent Relapse.

18. SGX393 inhibits the CML mutant Bcr-AblT1315I and preempts in vitro resistance when combined with nilotinib or dasatinib.

21. SGX70393 Inhibits Bcr-AblT315IIn Vitro and In Vivo and Completely Suppresses Resistance When Combined with Nilotinib or Dasatinib.

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