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3. Synthesis of benzoxazoles via a silver mediated oxidation

Author

Wong, Chloe D., primary, Ganjooi, Kimiya, additional, Verbarendse, Maetja, additional, Travis, Jessica M., additional, Troftgruben, Mark H. S., additional, Mora, Hannah R., additional, Oldenburg, Isabella, additional, Lammert, Robert, additional, Lazaro, Horacio, additional, and Eagon, Scott, additional

Published
2022
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4. Synthesis of benzoxazoles via a silver mediated oxidation.

Author

Wong, Chloe D., Ganjooi, Kimiya, Verbarendse, Maetja, Travis, Jessica M., Troftgruben, Mark H. S., Mora, Hannah R., Oldenburg, Isabella, Lammert Jr., Robert, Lazaro, Horacio, and Eagon, Scott

Subjects
*BENZOXAZOLES, *SILVER, *OXIDATION, *BIOACTIVE compounds, *WEATHER, *FUNCTIONAL groups, *AMINATION
Abstract

A silver carbonate-based method to synthesize benzoxazoles from imines has been developed. The reaction is extremely mild, tolerates several heterocycles and functional groups, and provides highly functionalized benzoxazoles in modest to good yields. The reaction proceeds in an array of solvents and atmospheric conditions, demonstrating the robustness of this oxidation method and its ability to provide an alternative method for the easy preparation and isolation of these bioactive compounds. [ABSTRACT FROM AUTHOR]

Published
2023
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