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19 results on '"Wolf, Asia-Sophia"'

1. Quality of antibody responses by adults and young children to 13-valent pneumococcal conjugate vaccination and Streptococcus pneumoniae colonisation

Author

Wolf, Asia-Sophia, Mitsi, Elena, Jones, Scott, Jochems, Simon P., Roalfe, Lucy, Thindwa, Deus, Meiring, James E., Msefula, Jacquline, Bonomali, Farouck, Makhaza Jere, Tikhala, Mbewe, Maurice, Collins, Andrea M., Gordon, Stephen B., Gordon, Melita A., Ferreira, Daniela M., French, Neil, Goldblatt, David, Heyderman, Robert S., and Swarthout, Todd D.

Published
2022
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2. Mass cytometry reveals cellular correlates of immune response heterogeneity to SARS-CoV-2 vaccination in the elderly

Author

Mukherjee, Ratnadeep, primary, Eggesbø, Linn, additional, Wolf, Asia-Sophia, additional, Kjønstad, Ingrid, additional, Solum, Guri, additional, Ravussin, Anthony, additional, Bhandari, Sabin, additional, Robertson, Anna, additional, Magnus, Per, additional, Trogstad, Lill-Iren Schou, additional, Kristoffersen, Anja, additional, Nygaard, Unni, additional, and Mjaaland, Siri, additional

Published
2024
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4. T Cell Responses to Repeated SARS-CoV-2 Vaccination and Breakthrough Infections in Patients on TNF Inhibitor Treatment: A Prospective Cohort Study

Author

Wolf, Asia-Sophia, primary, Bjørlykke, Kristin Hammersbøen, additional, Ørbo, Hilde S., additional, Bhandari, Sabin, additional, Solum, Guri, additional, Fadum Kjønstad, Ingrid, additional, Jyssum, Ingrid, additional, Nygaard, Unni C., additional, Kristoffersen, Anja Bråthen, additional, Christensen, Ingrid E., additional, Josefsson, Sarah E., additional, Persgård Lund, Katrine, additional, Chopra, Adity, additional, Tveter, Anne T., additional, Sexton, Joseph, additional, Kvien, Tore K., additional, Jahnsen, Jørgen, additional, Haavardsholm, Espen A., additional, Grødeland, Gunnveig, additional, Vaage, John Torgils, additional, Provan, Sella Aarrestad, additional, Kared, Hassen, additional, Lund-Johansen, Fridtjof, additional, Munthe, Ludvig André, additional, Syversen, Silje Watterdal, additional, Goll, Guro Løvik, additional, Jørgensen, Kristin Kaasen, additional, and Mjaaland, Siri, additional

Published
2024
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5. T cell responses to SARS-CoV-2 vaccination differ by disease-modifying therapy for multiple sclerosis

Author

Wolf, Asia-Sophia, primary, Ravussin, Anthony, additional, König, Marton, additional, Øverås, Mathias H., additional, Solum, Guri, additional, Kjønstad, Ingrid Fadum, additional, Chopra, Adity, additional, Holmøy, Trygve, additional, Harbo, Hanne F., additional, Syversen, Silje Watterdal, additional, Jørgensen, Kristin Kaasen, additional, Høgestøl, Einar August, additional, Vaage, Jon Torgils, additional, Celius, Elisabeth G., additional, Lund-Johansen, Fridtjof, additional, Munthe, Ludvig A., additional, Nygaard, Gro Owren, additional, and Mjaaland, Siri, additional

Published
2023
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6. Determinants of humoral and cellular immune responses to three doses of mRNA SARS-CoV-2 vaccines in older adults: a longitudinal cohort study

Author

Ravussin, Anthony, primary, Robertson, Anna Hayman, additional, Wolf, Asia-Sophia, additional, Blix, Kristine, additional, Kjønstad, Ingrid Fadum, additional, Solum, Guri, additional, Feiring, Berit, additional, Strand, Bjørn Heine, additional, Lund-Johansen, Fridtjof, additional, Munthe, Ludvig A, additional, Magnus, Per, additional, Trogstad, Lill, additional, and Mjaaland, Siri, additional

Published
2023
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7. T cell responses to SARS-CoV-2 vaccination in people with multiple sclerosis differ between disease-modifying therapies

Author

Wolf, Asia-Sophia, primary, Ravussin, Anthony, additional, König, Marton, additional, Øverås, Mathias H., additional, Solum, Guri, additional, Kjønstad, Ingrid Fadum, additional, Chopra, Adity, additional, Holmøy, Trygve, additional, Harbo, Hanne F., additional, Syversen, Silje Watterdal, additional, Jørgensen, Kristin Kaasen, additional, Høgestøl, Einar August, additional, Vaage, Jon Torgils, additional, Celius, Elisabeth G., additional, Lund-Johansen, Fridtjof, additional, Munthe, Ludvig A., additional, Nygaard, Gro Owren, additional, and Mjaaland, Siri, additional

Published
2022
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8. Thirteen-Valent Pneumococcal Conjugate Vaccine–Induced\ud Immunoglobulin G (IgG) Responses in Serum Associated With Serotype-Specific IgG in the Lung

Author

Mitsi, Elena, McLenaghan, Daniella, Wolf, Asia-Sophia, Jones, Scott, Collins, Andrea, Hyder-Wright, Angela, Goldblatt, David, Heyderman, Robert, Gordon, Stephen, and Ferreira, Daniela

Subjects
qw_575, qy_4, wc_217, qw_142, complex mixtures
Abstract

Pneumococcal conjugate vaccine (PCV) efficacy is lower for noninvasive pneumonia than invasive disease. In this study, participants were immunized with 13-valent PCV (PCV13) or hepatitis A vaccine (control). Bronchoalveolar lavage samples were taken between 2 and 6 months and serum at 4 and 7 weeks postvaccination. In the lung, anti-capsular immunoglobulin G (IgG) levels were higher in the PCV13 group compared to controls for all serotypes, except 3 and 6B. Systemically, IgG levels were elevated in the PCV13 group at 4 weeks for all serotypes, except serotype 3. IgG in bronchoalveolar lavage and serum positively correlated for nearly all serotypes. PCV13 shows poor immunogenicity to serotype 3, implying lack of protective efficacy.

Published
2022

9. Immunity in Omicron SARS-CoV-2 breakthrough COVID-19 in vaccinated adults

Author

Kared, Hassen, primary, Wolf, Asia-Sophia, additional, Alirezaylavasani, Amin, additional, Ravussin, Anthony, additional, Solum, Guri, additional, Tran, Trung The, additional, Lund-Johansen, Fridtjof, additional, Vaage, John Torgils, additional, Nissen-Meyer, Lise Sofie, additional, Nygaard, Unni C., additional, Hungnes, Olav, additional, Robertson, Anna H, additional, Næss, Lisbeth Meyer, additional, Trogstad, Lill, additional, Magnus, Per, additional, Munthe, Ludvig A, additional, and Mjaaland, Siri, additional

Published
2022
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10. Thirteen-Valent Pneumococcal Conjugate Vaccine–Induced Immunoglobulin G (IgG) Responses in Serum Associated With Serotype-Specific IgG in the Lung

Author

Mitsi, Elena, primary, McLenaghan, Daniella, additional, Wolf, Asia-Sophia, additional, Jones, Scott, additional, Collins, Andrea M, additional, Hyder-Wright, Angela D, additional, Goldblatt, David, additional, Heyderman, Robert S, additional, Gordon, Stephen B, additional, and Ferreira, Daniela M, additional

Published
2021
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15. Differentiation and adaptation of natural killer cells for anti‐malarial immunity.

Author

Goodier, Martin R., Wolf, Asia‐Sophia, and Riley, Eleanor M.

Subjects
*KILLER cells, *IMMUNITY, *IMMUNE response, *INTRACELLULAR pathogens, *CELL differentiation
Abstract

Natural killer cells employ a diverse arsenal of effector mechanisms to target intracellular pathogens. Differentiation of natural killer (NK) cell activation pathways occurs along a continuum from reliance on innate pro‐inflammatory cytokines and stress‐induced host ligands through to interaction with signals derived from acquired immune responses. Importantly, the degree of functional differentiation of the NK cell lineage influences the magnitude and specificity of interactions with host cells infected with viruses, bacteria, fungi, and parasites. Individual humans possess a vast diversity of distinct NK cell clones, each with the capacity to vary along this functional differentiation pathway, which ‐ when combined ‐ results in unique individual responses to different infections. Here we summarize these NK cell differentiation events, review evidence for direct interaction of malaria‐infected host cells with NK cells and assess how innate inflammatory signals induced by malaria parasite‐associated molecular patterns influence the indirect activation and function of NK cells. Finally, we discuss evidence that anti‐malarial immunity develops in parallel with advancing NK differentiation, coincident with a loss of reliance on inflammatory signals, and a refined capacity of NK cells to target malaria parasites more precisely, particularly through antibody‐dependent mechanisms. [ABSTRACT FROM AUTHOR]

Published
2020
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17. Calorie Restriction Attenuates Terminal Differentiation of Immune Cells

Author

White, Matthew J., primary, Beaver, Charlotte M., additional, Goodier, Martin R., additional, Bottomley, Christian, additional, Nielsen, Carolyn M., additional, Wolf, Asia-Sophia F. M., additional, Boldrin, Luisa, additional, Whitmore, Charlotte, additional, Morgan, Jennifer, additional, Pearce, Daniel J., additional, and Riley, Eleanor M., additional

Published
2017
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19. Thirteen-Valent Pneumococcal Conjugate Vaccine-Induced Immunoglobulin G (IgG) Responses in Serum Associated With Serotype-Specific IgG in the Lung.

Author

Mitsi E, McLenaghan D, Wolf AS, Jones S, Collins AM, Hyder-Wright AD, Goldblatt D, Heyderman RS, Gordon SB, and Ferreira DM

Subjects
Antibodies, Bacterial, Humans, Immunoglobulin G, Infant, Lung, Pneumococcal Vaccines, Serogroup, Vaccines, Conjugate, Pneumococcal Infections
Abstract

Pneumococcal conjugate vaccine (PCV) efficacy is lower for noninvasive pneumonia than invasive disease. In this study, participants were immunized with 13-valent PCV (PCV13) or hepatitis A vaccine (control). Bronchoalveolar lavage samples were taken between 2 and 6 months and serum at 4 and 7 weeks postvaccination. In the lung, anti-capsular immunoglobulin G (IgG) levels were higher in the PCV13 group compared to controls for all serotypes, except 3 and 6B. Systemically, IgG levels were elevated in the PCV13 group at 4 weeks for all serotypes, except serotype 3. IgG in bronchoalveolar lavage and serum positively correlated for nearly all serotypes. PCV13 shows poor immunogenicity to serotype 3, implying lack of protective efficacy. Clinical Trials Registration. ISRCTN 45340436., (© The Author(s) 2021. Published by Oxford University Press for the Infectious Diseases Society of America.)

Published
2022
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