Search

Your search keyword '"Wojnicz Romuald"' showing total 252 results
Start Over Author "Wojnicz Romuald"
252 results on '"Wojnicz Romuald"'

1. The rationale for using low-molecular weight heparin in the therapy of symptomatic COVID-19 patients

Author

Reichman-Warmusz Edyta, Warmusz Oliwia, and Wojnicz Romuald

Subjects
covid-19, inflammation, microvascular coagulapathy, anticoagulation, low-molecular weight heparin, Medicine
Abstract

Accumulated evidence suggest that the adverse outcome of severe coronavirus disease 2019 (COVID-19) is closely related to prothrombotic microvascular pathology with a high risk of venous thromboembolism. Furthermore, the first observational studies indicated that adjunct therapy with low-molecular weight heparin (LMWH) was associated with lower mortality in this cohort of patients. However, the timing of starting LMWH and the dose remain controversial in COVID-19 patients. Considering the above, the aim of this study was to reveal the rationale for using LMWH in the therapy of symptomatic COVID-19 patients based on experimental and clinical studies on LMWH in inflammatory settings with special consideration given to randomized trials.

Published
2022
Full Text
View/download PDF

2. Computerized Systems Supporting Clinical Decision in Medicine

Author

Owczarek Aleksander J., Smertka Mike, Jędrusik Przemysław, Gębska-Kuczerowska Anita, Chudek Jerzy, and Wojnicz Romuald

Subjects
History of scholarship and learning. The humanities, AZ20-999
Abstract

Statistics is the science of collection, summarizing, presentation and interpretation of data. Moreover, it yields methods used in the verification of research hypotheses. The presence of a statistician in a research group remarkably improves both the quality of design and research and the optimization of financial resources. Moreover, the involvement of a statistician in a research team helps the physician to effectively utilize the time and energy spent on diagnosing, which is an important aspect in view of limited healthcare resources. Precise, properly designed and implemented Computerized Clinical Decision Support Systems certainly lead to the improvement of healthcare and the quality of medical services, which increases patient satisfaction and reduces financial burdens on healthcare systems.

Published
2018
Full Text
View/download PDF

16. A multicenter, randomized, double-blind, placebo-controlled study to evaluate the efficacy of immunosuppression in biopsy-proven virus-negative myocarditis or inflammatory cardiomyopathy (IMPROVE-MC)

Author

Ozierański, Krzysztof, primary, Tymińska, Agata, additional, Marchel, Michał, additional, Januszkiewicz, Łukasz, additional, Maciejewski, Cezary, additional, Główczyńska, Renata, additional, Marcolongo, Renzo, additional, Caforio, Alida LP, additional, Wojnicz, Romuald, additional, Mizia-Stec, Katarzyna, additional, Grzybowski, Jacek, additional, Gąsior, Mariusz, additional, Nowalany-Kozielska, Ewa, additional, Pawlak, Agnieszka, additional, Kaczmarek, Krzysztof, additional, Żegarska, Jolanta, additional, Pączek, Leszek, additional, Balsam, Paweł, additional, Opolski, Grzegorz, additional, and Grabowski, Marcin, additional

Published
2022
Full Text
View/download PDF

32. The vaping product use associated lung injury: is this a new pulmonary disease entity?

Author

Mado, Hubert, Reichman-Warmusz, Edyta, and Wojnicz, Romuald

Abstract

In the summer of 2019, an epidemic of e-cigarette or vaping product use associated lung injury (EVALI) broke out in the United States of America. EVALI is a lung disease that can be severe and life-threatening. It should be emphasized that EVALI is not a clinical diagnosis, but surveillance case definition. Due to the profile of users of such devices, the pathology mainly affects young adults, although cases of EVALI have been reported in almost all age groups, from teenage children to seniors. The worst prognosis is in patients over 35 years of age, with accompanying diseases. A significant number of patients declared the use of products containing tetrahydrocannabinol (THC). The most likely factor responsible for the occurrence of EVALI is vitamin E acetate, which is sometimes added to liquids necessary for the use of electronic cigarette type devices, especially those liquids that contain THC. Nevertheless, it is possible that other substances used in liquids may also be a causative factor. Typical for EVALI are respiratory, gastrointestinal and systemic symptoms, while in imaging tests, a characteristic feature of EVALI is the presence of opacities on the chest radiogram and ground-glass clouds on computed tomography scans. In the course of this disease, respiratory failure often occurs (58%). In the vast majority of cases oxygen substitution is necessary. Currently, the best treatment of EVALI is considered to be the administration of systemic glucocorticosteroids. Over 90% of patients with EVALI required hospitalization, while the mortality rate was about 2.42%. Median age of the fatalities was 51 years. The aim of this review is to summarise the available information on EVALI and to consider possible causative factors and pathomechanism. [ABSTRACT FROM AUTHOR]

Published
2021
Full Text
View/download PDF

34. Methodological problems in the measurement of interleukin-33 concentrations in patients with heart failure with a reduced ejection fraction

Author

Segiet, Oliwia Anna, Romuk, Ewa, Nowalany-Kozielska, Ewa, Wojciechowska, Celina, Piecuch, Adam, and Wojnicz, Romuald

Subjects
Ventricular Dysfunction, Left, lcsh:Diseases of the circulatory (Cardiovascular) system, inflammation, lcsh:RC666-701, Humans, heart failure, cytokine expression, Stroke Volume, Interleukin-33, Letter to the Editor
Published
2019

41. Apoptosis in Primary Hyperparathyroidism

Author

Segiet, Oliwia Anna, primary, Mielańczyk, Łukasz, additional, Piecuch, Adam, additional, Michalski, Marek, additional, Tyczyński, Szczepan, additional, Brzozowa-Zasada, Marlena, additional, Deska, Mariusz, additional, and Wojnicz, Romuald, additional

Published
2017
Full Text
View/download PDF

43. The concentration of interleukin-33 in heart failure with reduced ejection fraction.

Author

Segiet, Oliwia Anna, Romuk, Ewa, Nowalany-Kozielska, Ewa, Wojciechowska, Celina, Piecuch, Adam, and Wojnicz, Romuald

Subjects
INTERLEUKIN-33, HEART failure, ETIOLOGY of diseases, ENZYME-linked immunosorbent assay, INCURABLE diseases
Abstract

Objective: Despite several improvements in the management of heart failure (HF), it is still an incurable and a progressive disease. Several trials demonstrated that the process of inflammation may be responsible for initiation and progression of HF. The aim of the present study was to investigate the role of interleukin-33 (IL-33) in the pathogenesis of HF and to assess whether disease etiology and course of the disease affect the expression of cytokines. Methods: The study included 155 (106 male and 49 female) patients with systolic HF with a mean left ventricle ejection fraction of 32.13}12.8% and 60 (36 male and 24 female) healthy individuals. IL-33 concentrations were evaluated using enzyme-linked immunosorbent assay. Results: The concentration of IL-33 was statistically significantly lower in patients with HF than in healthy subjects, 16.91 (0-81.00) pg/mL and 92.51 (33.61-439.61) pg/mL, respectively. Patients with HF with ischemic etiology had lower concentration of IL-33 (10.75 pg/mL) than subjects with HF with non-ischemic etiology (21.05 pg/mL). Patients with stable HF (10.46 pg/mL) had lower IL-33 levels than those with unstable HF (19.02 pg/mL). Conclusion: The concentrations of IL-33 were lower in patients with HF than in healthy controls, which may play an important role of above cytokine in HF development and progression. In addition, interleukin concentrations varied depending on the etiology and severity of the course of the disease. [ABSTRACT FROM AUTHOR]

Published
2019
Full Text
View/download PDF

50. Markers of apoptosis in thyroid goiter

Author

Segiet, Oliwia, primary, Mielańczyk, Łukasz, additional, Michalski, Marek, additional, Matysiak, Natalia, additional, Klymenko, Olesya, additional, Helewski, Krzysztof, additional, and Wojnicz, Romuald, additional

Published
2016
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results