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283 results on '"Wojakowski, Wojtek"'

2. TransCatheter aortic valve implantation and fractional flow reserve-guided percutaneous coronary intervention versus conventional surgical aortic valve replacement and coronary bypass grafting for treatment of patients with aortic valve stenosis and multivessel or advanced coronary disease: The transcatheter valve and vessels trial (TCW trial): Design and rationale

Author

Kedhi, Elvin, Rroku, Andi, Hermanides, Rik S., Dambrink, Jan Henk, Singh, Sandeep, Berg, Jurriën Ten, van Ginkel, Dirk-Jan, Hudec, Martin, Amoroso, Giovanni, Amat-Santos, Ignacio J., Andreas, Martin, Teles, Rui Campante, Bonnet, Guillaume, Van Belle, Eric, Conradi, Lenard, van Garsse, Leen, Wojakowski, Wojtek, Voudris, Vasileious, Sacha, Jerzy, Cervinka, Pavel, Lipsic, Erik, Somi, Samer, Nombela-Franco, Luis, Postma, Sonja, Piayda, Kerstin, De Luca, Giuseppe, Malinofski, Krzysztof, and Modine, Thomas

Published
2024
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8. Reductions in remnant cholesterol and VLDL cholesterol through inhibition of ANGPTL3 protein synthesis: an analysis from the TRANSLATE-TIMI 70 trial

Author

Zimerman, Andre, primary, Wiviott, Stephen D, additional, Park, Jeong-Gun, additional, Murphy, Sabina A, additional, Ran, Xinhui, additional, Bramson, Candace R, additional, Curto, Madelyn, additional, Ramos, Vesper, additional, Jevne, Alexandra, additional, Kuder, Julia F, additional, Verma, Subodh, additional, Wojakowski, Wojtek, additional, Terra, Steven G, additional, Sabatine, Marc S, additional, Bergmark, Brian A, additional, and Marston, Nicholas A, additional

Published
2024
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9. Surgical Treatment of Patients With Infective Endocarditis After Transcatheter Aortic Valve Implantation

Author

Mangner, Norman, del Val, David, Abdel-Wahab, Mohamed, Crusius, Lisa, Durand, Eric, Ihlemann, Nikolaj, Urena, Marina, Pellegrini, Costanza, Giannini, Francesco, Gasior, Tomasz, Wojakowski, Wojtek, Landt, Martin, Auffret, Vincent, Sinning, Jan Malte, Cheema, Asim N., Nombela-Franco, Luis, Chamandi, Chekrallah, Campelo-Parada, Francisco, Munoz-Garcia, Erika, Herrmann, Howard C., Testa, Luca, Kim, Won-Keun, Castillo, Juan Carlos, Alperi, Alberto, Tchetche, Didier, Bartorelli, Antonio L., Kapadia, Samir, Stortecky, Stefan, Amat-Santos, Ignacio, Wijeysundera, Harindra C., Lisko, John, Gutiérrez-Ibanes, Enrique, Serra, Vicenç, Salido, Luisa, Alkhodair, Abdullah, Livi, Ugolino, Chakravarty, Tarun, Lerakis, Stamatios, Vilalta, Victoria, Regueiro, Ander, Romaguera, Rafael, Kappert, Utz, Barbanti, Marco, Masson, Jean-Bernard, Maes, Frédéric, Fiorina, Claudia, Miceli, Antonio, Kodali, Susheel, Ribeiro, Henrique B., Mangione, Jose Armando, Sandoli de Brito, Fabio, Jr., Actis Dato, Guglielmo Mario, Rosato, Francesco, Ferreira, Maria-Cristina, Correia de Lima, Valter, Colafranceschi, Alexandre Siciliano, Abizaid, Alexandre, Marino, Marcos Antonio, Esteves, Vinicius, Andrea, Julio, Godinho, Roger R., Alfonso, Fernando, Eltchaninoff, Helene, Søndergaard, Lars, Himbert, Dominique, Husser, Oliver, Latib, Azeem, Le Breton, Hervé, Servoz, Clement, Pascual, Isaac, Siddiqui, Saif, Olivares, Paolo, Hernandez-Antolin, Rosana, Webb, John G., Sponga, Sandro, Makkar, Raj, Kini, Annapoorna S., Boukhris, Marouane, Gervais, Philippe, Côté, Mélanie, Holzhey, David, Linke, Axel, and Rodés-Cabau, Josep

Published
2022
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10. Infective Endocarditis Caused by Staphylococcus aureus After Transcatheter Aortic Valve Replacement

Author

del Val, David, Abdel-Wahab, Mohamed, Mangner, Norman, Durand, Eric, Ihlemann, Nikolaj, Urena, Marina, Pellegrini, Costanza, Giannini, Francesco, Gasior, Tomasz, Wojakowski, Wojtek, Landt, Martin, Auffret, Vincent, Sinning, Jan Malte, Cheema, Asim N., Nombela-Franco, Luis, Chamandi, Chekrallah, Campelo-Parada, Francisco, Munoz-Garcia, Erika, Herrmann, Howard C., Testa, Luca, Won-Keun, Kim, Castillo, Juan Carlos, Alperi, Alberto, Tchetche, Didier, Bartorelli, Antonio L., Kapadia, Samir, Stortecky, Stefan, Amat-Santos, Ignacio, Wijeysundera, Harindra C., Lisko, John, Gutiérrez-Ibanes, Enrique, Serra, Vicenç, Salido, Luisa, Alkhodair, Abdullah, Vendramin, Igor, Chakravarty, Tarun, Lerakis, Stamatios, Vilalta, Victoria, Regueiro, Ander, Romaguera, Rafael, Kappert, Utz, Barbanti, Marco, Masson, Jean-Bernard, Maes, Frédéric, Fiorina, Claudia, Miceli, Antonio, Kodali, Susheel, Ribeiro, Henrique B., Mangione, Jose Armando, Sandoli de Brito, Fabio, Jr., Actis Dato, Guglielmo Mario, Rosato, Francesco, Ferreira, Maria-Cristina, Corriea de Lima, Valter, Colafranceschi, Alexandre Siciliano, Abizaid, Alexandre, Marino, Marcos Antonio, Esteves, Vinicius, Andrea, Julio, Godinho, Roger R., Alfonso, Fernando, Eltchaninoff, Helene, Søndergaard, Lars, Himbert, Dominique, Husser, Oliver, Latib, Azeem, Le Breton, Hervé, Servoz, Clement, Pascual, Isaac, Siddiqui, Saif, Olivares, Paolo, Hernandez-Antolin, Rosana, Webb, John G., Sponga, Sandro, Makkar, Raj, Kini, Annapoorna S., Boukhris, Marouane, Gervais, Philippe, Linke, Axel, Crusius, Lisa, Holzhey, David, and Rodés-Cabau, Josep

Published
2022
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11. Global position paper on cardiovascular regenerative medicine

Author

Fernández-Avilés, Francisco, Sanz-Ruiz, Ricardo, Climent, Andreu M, Badimon, Lina, Bolli, Roberto, Charron, Dominique, Fuster, Valentin, Janssens, Stefan, Kastrup, Jens, Kim, Hyo-Soo, Lüscher, Thomas F, Martin, John F, Menasché, Philippe, Simari, Robert D, Stone, Gregg W, Terzic, Andre, Willerson, James T, Wu, Joseph C, Group, the TACTICS Writing, Broughton, Kathleen, DiFede, Darcy L, Dimmeler, Stefanie, Madonna, Rosalinda, Penn, Marc S, Sussman, Mark A, Sluijter, Joost PG, Wollert, Kai C, Balkan, Wayne, Chamuleau, Steven, Fernández-Santos, María Eugenia, Goliasch, Georg, Gyöngyösi, Mariann, Hare, Joshua M, Tompkins, Bryon A, Winkler, Johannes, Bayés-Genís, Antoni, Henry, Timothy D, Taylor, Doris A, Lerman, Amir, Pelacho, Beatriz, Prosper, Felipe, Perin, Emerson C, Pompilio, Giulio, Gersh, Bernard, Bartunek, Jozef, Duckers, Eric, Ferdinandy, Péter, Losordo, Douglas W, Sánchez, Pedro L, Sherman, Warren, Wojakowski, Wojtek, Zeiher, Andreas, Roncalli, Jerome, Mathur, Anthony, Crea, Filippo, D´Amario, Domenico, Povsic, Thomas J, Traverse, Jay, and Ylä-Herttuala, Seppo

Subjects
Biomedical and Clinical Sciences, Cardiovascular Medicine and Haematology, Clinical Sciences, Cardiovascular Diseases, Consensus, Humans, Precision Medicine, Regenerative Medicine, TACTICS (Transnational Alliance for Regenerative Therapies in Cardiovascular Syndromes) Writing Group, Authors/Task Force Members. Chairpersons, Basic Research Subcommittee, Translational Research Subcommittee, Challenges of Cardiovascular Regenerative Medicine Subcommittee, Tissue Engineering Subcommittee, Delivery, Navigation, Tracking and Assessment Subcommittee, Clinical Trials Subcommittee, Regulatory and funding strategies subcommittee, Delivery, Navigation, Tracking and Assessment Subcommittee, Cardiorespiratory Medicine and Haematology, Cardiovascular System & Hematology, Cardiovascular medicine and haematology, Clinical sciences
Published
2017

12. Impact of SARS-CoV-2 positivity on clinical outcome among STEMI patients undergoing mechanical reperfusion: Insights from the ISACS STEMI COVID 19 registry

Author

De Luca, Giuseppe, Debel, Niels, Cercek, Miha, Jensen, Lisette Okkels, Vavlukis, Marija, Calmac, Lucian, Johnson, Tom, Ferrer, Gerard Rourai, Ganyukov, Vladimir, Wojakowski, Wojtek, Kinnaird, Tim, von Birgelen, Clemens, Cottin, Yves, IJsselmuiden, Alexander, Tuccillo, Bernardo, Versaci, Francesco, Royaards, Kees-Jan, Berg, Jurrien ten, Laine, Mika, Dirksen, Maurits, Siviglia, Massimo, Casella, Gianni, Kala, Petr, Díez Gil, José Luis, Banning, Adrian, Becerra, Victor, De Simone, Ciro, Santucci, Andrea, Carrillo, Xavier, Scoccia, Alessandra, Amoroso, Giovanni, van't Hof, Arnoud WJ., Kovarnik, Tomas, Tsigkas, Grigorios, Mehilli, Julinda, Gabrielli, Gabriele, Rios, Xacobe Flores, Bakraceski, Nikola, Levesque, Sébastien, Cirrincione, Giuseppe, Guiducci, Vincenzo, Kidawa, Michał, Spedicato, Leonardo, Marinucci, Lucia, Ludman, Peter, Zilio, Filippo, Galasso, Gennaro, Fabris, Enrico, Menichelli, Maurizio, Garcia-Touchard, Arturo, Manzo, Stephane, Caiazzo, Gianluca, Moreu, Jose, Forés, Juan Sanchis, Donazzan, Luca, Vignali, Luigi, Teles, Rui, Benit, Edouard, Agostoni, Pierfrancesco, Ojeda, Francisco Bosa, Lehtola, Heidi, Camacho-Freiere, Santiago, Kraaijeveld, Adriaan, Antti, Ylitalo, Boccalatte, Marco, Deharo, Pierre, Martínez-Luengas, Iñigo Lozano, Scheller, Bruno, Varytimiadi, Efthymia, Moreno, Raul, Uccello, Giuseppe, Faurie, Benjamin, Gutierrez Barrios, Alejandro, Milewski, Marek, Bruwiere, Ewout, Smits, Pieter, Wilbert, Bor, Di Uccio, Fortunato Scotto, Parodi, Guido, Kedhi, Elvin, and Verdoia, Monica

Published
2021
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13. Hepatic Fat Changes with Antisense Oligonucleotide Therapy Targeting ANGPTL3

Author

Zimerman, Andre, primary, Wiviott, Stephen D., additional, Park, Jeong-Gun, additional, Murphy, Sabina A., additional, Ran, Xinhui, additional, Bramson, Candace R., additional, Curto, Madelyn, additional, Ramos, Vesper, additional, Jevne, Alexandra, additional, Kuder, Julia F., additional, Verma, Subodh, additional, Wojakowski, Wojtek, additional, Terra, Steven G., additional, Sabatine, Marc S., additional, Bergmark, Brian A., additional, and Marston, Nicholas A., additional

Published
2023
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14. Predictors of Device-Related Thrombus Following Percutaneous Left Atrial Appendage Occlusion

Author

Simard, Trevor, Jung, Richard G., Lehenbauer, Kyle, Piayda, Kerstin, Pracoń, Radoslaw, Jackson, Gregory G., Flores-Umanzor, Eduardo, Faroux, Laurent, Korsholm, Kasper, Chun, Julian K.R., Chen, Shaojie, Maarse, Moniek, Montrella, Kristi, Chaker, Zakeih, Spoon, Jocelyn N., Pastormerlo, Luigi E., Meincke, Felix, Sawant, Abhishek C., Moldovan, Carmen M., Qintar, Mohammed, Aktas, Mehmet K., Branca, Luca, Radinovic, Andrea, Ram, Pradhum, El-Zein, Rayan S., Flautt, Thomas, Ding, Wern Yew, Sayegh, Bassel, Benito-González, Tomás, Lee, Oh-Hyun, Badejoko, Solomon O., Paitazoglou, Christina, Karim, Nabeela, Zaghloul, Ahmed M., Agrawal, Himanshu, Kaplan, Rachel M., Alli, Oluseun, Ahmed, Aamir, Suradi, Hussam S., Knight, Bradley P., Alla, Venkata M., Panaich, Sidakpal S., Wong, Tom, Bergmann, Martin W., Chothia, Rashaad, Kim, Jung-Sun, Pérez de Prado, Armando, Bazaz, Raveen, Gupta, Dhiraj, Valderrabano, Miguel, Sanchez, Carlos E., El Chami, Mikhael F., Mazzone, Patrizio, Adamo, Marianna, Ling, Fred, Wang, Dee Dee, O’Neill, William, Wojakowski, Wojtek, Pershad, Ashish, Berti, Sergio, Spoon, Daniel, Kawsara, Akram, Jabbour, George, Boersma, Lucas V.A., Schmidt, Boris, Nielsen-Kudsk, Jens Erik, Rodés-Cabau, Josep, Freixa, Xavier, Ellis, Christopher R., Fauchier, Laurent, Demkow, Marcin, Sievert, Horst, Main, Michael L., Hibbert, Benjamin, Holmes, David R., Jr., and Alkhouli, Mohamad

Published
2021
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15. Impact of renin-angiotensin system inhibitors on mortality during the COVID Pandemic among STEMI patients undergoing mechanical reperfusion: Insight from an international STEMI registry

Author

De Luca, Giuseppe, Cercek, Miha, Okkels Jensen, Lisette, Bushljetikj, Oliver, Calmac, Lucian, Johnson, Tom, Gracida Blancas, Montserrat, Ganyukov, Vladimir, Wojakowski, Wojtek, von Birgelen, Clemens, IJsselmuiden, Alexander, Tuccillo, Bernardo, Versaci, Francesco, Ten Berg, Jurrien, Laine, Mika, Berkout, Tim, Casella, Gianni, Kala, Petr, López Ledesma, Bernabé, Becerra, Victor, Padalino, Roberto, Santucci, Andrea, Carrillo, Xavier, Scoccia, Alessandra, Amoroso, Giovanni, Lux, Arpad, Kovarnik, Tomas, Davlouros, Periklis, Gabrielli, Gabriele, Flores Rios, Xacobe, Bakraceski, Nikola, Levesque, Sébastien, Guiducci, Vincenzo, Kidawa, Michał, Marinucci, Lucia, Zilio, Filippo, Galasso, Gennaro, Fabris, Enrico, Menichelli, Maurizio, Manzo, Stephane, Caiazzo, Gianluca, Moreu, Jose, Sanchis Forés, Juan, Donazzan, Luca, Vignali, Luigi, Teles, Rui, Agostoni, Pierfrancesco, Bosa Ojeda, Francisco, Lehtola, Heidi, Camacho-Freiere, Santiago, Kraaijeveld, Adriaan, Antti, Ylitalo, Visconti, Gabriella, Lozano Martínez-Luengas, Iñigo, Scheller, Bruno, Alexopulos, Dimitrios, Moreno, Raul, Kedhi, Elvin, Uccello, Giuseppe, Faurie, Benjamin, Gutierrez Barrios, Alejandro, Scotto Di Uccio, Fortunato, Wilbert, Bor, Cortese, Giuliana, Dirksen, Maurits T., Parodi, Guido, and Verdoia, Monica

Published
2021
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16. Stroke Complicating Infective Endocarditis After Transcatheter Aortic Valve Replacement

Author

del Val, David, Abdel-Wahab, Mohamed, Mangner, Norman, Durand, Eric, Ihlemann, Nikolaj, Urena, Marina, Pellegrini, Costanza, Giannini, Francesco, Gasior, Tomasz, Wojakowski, Wojtek, Landt, Martin, Auffret, Vincent, Sinning, Jan Malte, Cheema, Asim N., Nombela-Franco, Luis, Chamandi, Chekrallah, Campelo-Parada, Francisco, Munoz-Garcia, Erika, Herrmann, Howard C., Testa, Luca, Won-Keun, Kim, Castillo, Juan Carlos, Alperi, Alberto, Tchetche, Didier, Bartorelli, Antonio L., Kapadia, Samir, Stortecky, Stefan, Amat-Santos, Ignacio, Wijeysundera, Harindra C., Lisko, John, Gutiérrez-Ibanes, Enrique, Serra, Vicenç, Salido, Luisa, Alkhodair, Abdullah, Livi, Ugolino, Chakravarty, Tarun, Lerakis, Stamatios, Vilalta, Victoria, Regueiro, Ander, Romaguera, Rafael, Kappert, Utz, Barbanti, Marco, Masson, Jean-Bernard, Maes, Frédéric, Fiorina, Claudia, Miceli, Antonio, Kodali, Susheel, Ribeiro, Henrique B., Mangione, Jose Armando, Sandoli de Brito Jr, Fabio, Actis Dato, Guglielmo Mario, Rosato, Francesco, Ferreira, Maria-Cristina, Correia de Lima, Valter, Colafranceschi, Alexandre Siciliano, Abizaid, Alexandre, Marino, Marcos Antonio, Esteves, Vinicius, Andrea, Julio, Godinho, Roger R., Alfonso, Fernando, Eltchaninoff, Helene, Søndergaard, Lars, Himbert, Dominique, Husser, Oliver, Latib, Azeem, Le Breton, Hervé, Servoz, Clement, Pascual, Isaac, Siddiqui, Saif, Olivares, Paolo, Hernandez-Antolin, Rosana, Webb, John G., Sponga, Sandro, Makkar, Raj, Kini, Annapoorna S., Boukhris, Marouane, Gervais, Philippe, Linke, Axel, Crusius, Lisa, Holzhey, David, and Rodés-Cabau, Josep

Published
2021
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17. International evaluation of an artificial intelligence-powered ecg model detecting acute coronary occlusion myocardial infarction

Author

Herman, Robert, primary, Meyers, H Pendell, additional, Smith, Stephen W, additional, Bertolone, Dario T, additional, Leone, Attilio, additional, Bermpeis, Konstantinos, additional, Viscusi, Michele M, additional, Belmonte, Marta, additional, Demolder, Anthony, additional, Boza, Vladimir, additional, Vavrik, Boris, additional, Kresnakova, Viera, additional, Iring, Andrej, additional, Martonak, Michal, additional, Bahyl, Jakub, additional, Kisova, Timea, additional, Schelfaut, Dan, additional, Vanderheyden, Marc, additional, Perl, Leor, additional, Aslanger, Emre K, additional, Hatala, Robert, additional, Wojakowski, Wojtek, additional, Bartunek, Jozef, additional, and Barbato, Emanuele, additional

Published
2023
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18. Persistent and Recurrent Device-Related Thrombus After Left Atrial Appendage Closure

Author

Mesnier, Jules, primary, Simard, Trevor, additional, Jung, Richard G., additional, Lehenbauer, Kyle R., additional, Piayda, Kerstin, additional, Pracon, Radoslaw, additional, Jackson, Gregory G., additional, Flores-Umanzor, Eduardo, additional, Faroux, Laurent, additional, Korsholm, Kasper, additional, Chun, Julian K.R., additional, Chen, Shaojie, additional, Maarse, Moniek, additional, Montrella, Kristi, additional, Chaker, Zakeih, additional, Spoon, Jocelyn N., additional, Pastormerlo, Luigi E., additional, Meincke, Felix, additional, Sawant, Abhishek C., additional, Moldovan, Carmen M., additional, Qintar, Mohammed, additional, Aktas, Mehmet K., additional, Branca, Luca, additional, Radinovic, Andrea, additional, Ram, Pradhum, additional, El-Zein, Rayan S., additional, Flautt, Thomas, additional, Ding, Wern Yew, additional, Sayegh, Bassel, additional, Benito-González, Tomás, additional, Lee, Oh-Hyun, additional, Badejoko, Solomon O., additional, Paitazoglou, Christina, additional, Karim, Nabeela, additional, Zaghloul, Ahmed M., additional, Agarwal, Himanshu, additional, Kaplan, Rachel M., additional, Alli, Oluseun, additional, Ahmed, Aamir, additional, Suradi, Hussam S., additional, Knight, Bradley P., additional, Alla, Venkata M., additional, Panaich, Sidakpal S., additional, Wong, Tom, additional, Bergmann, Martin W., additional, Chothia, Rashaad, additional, Kim, Jung-Sun, additional, Pérez de Prado, Armando, additional, Bazaz, Raveen, additional, Gupta, Dhiraj, additional, Valderrábano, Miguel, additional, Sanchez, Carlos E., additional, El Chami, Mikhael F., additional, Mazzone, Patrizio, additional, Adamo, Marianna, additional, Ling, Fred, additional, Wang, Dee Dee, additional, O’Neill, William, additional, Wojakowski, Wojtek, additional, Pershad, Ashish, additional, Berti, Sergio, additional, Spoon, Daniel B., additional, Kawsara, Akram, additional, Jabbour, George, additional, Boersma, Lucas V.A., additional, Schmidt, Boris, additional, Nielsen-Kudsk, Jens Erik, additional, Freixa, Xavier, additional, Ellis, Christopher R., additional, Fauchier, Laurent, additional, Demkow, Marcin, additional, Sievert, Horst, additional, Main, Michael L., additional, Hibbert, Benjamin, additional, Holmes, David R., additional, Alkhouli, Mohamad, additional, and Rodés-Cabau, Josep, additional

Published
2023
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19. TCT-93 Association Between Post-PCI vFFR and OCT Findings: Results From the FAST OCT Study

Author

Daemen, Joost, primary, Ziedses des Plantes, Anniek, additional, Scoccia, Alessandra, additional, Groenland, Frederik, additional, Forero, Maria Tovar, additional, Tomaniak, Mariusz, additional, Kochman, Janusz, additional, Wojakowski, Wojtek, additional, Ameloot, Koen, additional, Adriaenssens, Tom, additional, Dekker, Wijnand den, additional, Nuis, Rutger-Jan, additional, Kardys, Isabella, additional, van Mieghem, Nicolas, additional, and Spitzer, Ernest, additional

Published
2023
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20. TCT-596 Sex Differences in Use of Fractional Flow Reserve in Patients Undergoing Coronary Angiography and Percutaneous Coronary Intervention

Author

Bujak, Marta, primary, Malinowski, Krzysztof, additional, Siudak, Zbigniew, additional, Lesiak, Maciej, additional, Bartus, Stanislaw, additional, Legutko, Jacek, additional, Witkowski, Adam, additional, Dudek, Dariusz, additional, Gąsior, Mariusz, additional, Gil, Robert, additional, Protasiewicz, Marcin, additional, Kubica, Jacek, additional, Wojakowski, Wojtek, additional, and Gasior, Pawel, additional

Published
2023
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21. TCT-490 Sex-Specific Temporal Trends in Incidence and Outcomes of Cardiogenic Shock in Acute Myocardial Infarction Patients Treated With Percutaneous Coronary Intervention

Author

Bujak, Kamil, primary, Trzeciak, Przemysław, additional, Tajstra, Mateusz, additional, Stępińska, Janina, additional, Wojakowski, Wojtek, additional, Dudek, Dariusz, additional, Witkowski, Adam, additional, Gil, Robert J., additional, Legutko, Jacek, additional, Gierlotka, Marek, additional, Kuliczkowski, Wiktor, additional, and Gąsior, Mariusz, additional

Published
2023
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22. TCT-140 Combined Coexistence of Multiple Vulnerable Plaque Features is Associated With Incremental Rates of Adverse Events in Patients With Diabetes Mellitus: New Insights From the COMBINE OCT-FFR Trial

Author

Val, David del, primary, Berta, Balazs, additional, Roleder, Tomasz, additional, Malinowski, Krzysztof, additional, Bastante, Teresa, additional, Hermanides, Rik, additional, Wojakowski, Wojtek, additional, Fabris, Enrico, additional, Cuesta, Javier, additional, de Luca, Giuseppe, additional, Rivero, Fernando, additional, Alfonso, Fernando, additional, and Kedhi, Elvin, additional

Published
2023
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25. Guía ESC/EACTS 2021 sobre el diagnóstico y tratamiento de las valvulopatías: Desarrollada por el Grupo de Trabajo de la Sociedad Europea de Cardiología (ESC) y la European Association for Cardio-Thoracic Surgery (EACTS) sobre el diagnóstico y tratamiento de las valvulopatías

Author

Vahanian, Alec, Beyersdorf, Friedhelm, Praz, Fabien, Milojevic, Milan, Baldus, Stephan, Bauersachs, Johann, Capodanno, Davide, Conradi, Lenard, De Bonis, Michele, De Paulis, Ruggero, Delgado, Victoria, Freemantle, Nick, Gilard, Martine, Haugaa, Kristina H., Jeppsson, Anders, Jüni, Peter, Pierard, Luc, Prendergast, Bernard D., Rafael Sádaba, J., Tribouilloy, Christophe, and Wojakowski, Wojtek

Published
2022
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26. Impact of COVID-19 pandemic and diabetes on mechanical reperfusion in patients with STEMI: insights from the ISACS STEMI COVID 19 Registry

Author

De Luca, Giuseppe, Cercek, Miha, Jensen, Lisette Okkels, Vavlukis, Marija, Calmac, Lucian, Johnson, Tom, Roura i Ferrer, Gerard, Ganyukov, Vladimir, Wojakowski, Wojtek, von Birgelen, Clemens, Versaci, Francesco, Ten Berg, Jurrien, Laine, Mika, Dirksen, Maurits, Casella, Gianni, Kala, Petr, Díez Gil, José Luis, Becerra, Victor, De Simone, Ciro, Carrill, Xavier, Scoccia, Alessandra, Lux, Arpad, Kovarnik, Tomas, Davlouros, Periklis, Gabrielli, Gabriele, Flores Rios, Xacobe, Bakraceski, Nikola, Levesque, Sébastien, Guiducci, Vincenzo, Kidawa, Michał, Marinucci, Lucia, Zilio, Filippo, Galasso, Gennaro, Fabris, Enrico, Menichelli, Maurizio, Manzo, Stephane, Caiazzo, Gianluca, Moreu, Jose, Sanchis Forés, Juan, Donazzan, Luca, Vignali, Luigi, Teles, Rui, Bosa Ojeda, Francisco, Lehtola, Heidi, Camacho-Freiere, Santiago, Kraaijeveld, Adriaan, Antti, Ylitalo, Boccalatte, Marco, Martínez-Luengas, Iñigo Lozano, Scheller, Bruno, Alexopoulos, Dimitrios, Uccello, Giuseppe, Faurie, Benjamin, Gutierrez Barrios, Alejandro, Wilbert, Bor, Cortese, Giuliana, Moreno, Raul, Parodi, Guido, Kedhi, Elvin, and Verdoia, Monica

Published
2020
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27. INTERNATIONAL EVALUATION OF AN ARTIFICIAL INTELLIGENCE-POWERED ECG MODEL DETECTING OCCLUSION MYOCARDIAL INFARCTION

Author

Herman, Robert, primary, Meyers, H Pendell, additional, Smith, Stephen W, additional, Bertolone, Dario Tino, additional, Leone, Attilio, additional, Bermpeis, Kostantinos, additional, Viscusi, Michele M, additional, Belmonte, Marta, additional, Demolder, Anthony, additional, Boza, Vladimir, additional, Vavrik, Boris, additional, Kresnakova, Viera, additional, Iring, Andrej, additional, Martonak, Michal, additional, Bahyl, Jakub, additional, Kisova, Timea, additional, Schelfaut, Dan, additional, Vanderheyden, Marc, additional, Perl, Leor, additional, Aslanger, Emre, additional, Hatala, Robert, additional, Wojakowski, Wojtek, additional, Bartunek, Jozef, additional, and Barbato, Emanuele, additional

Published
2023
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29. Patterns of Aortic Valve Replacement in Europe: Adoption by Age.

Author

Rudolph, Tanja, Appleby, Clare, Delgado, Victoria, Eltchaninoff, Helene, Gebhard, Catherine, Hengstenberg, Christian, Wojakowski, Wojtek, Petersen, Nathan, Kurucova, Jana, Bramlage, Peter, and Bleiziffer, Sabine

Subjects
AORTIC valve transplantation, AGE groups, OLDER patients
Abstract

Introduction: The management of patients with severe aortic stenosis may differ according to patients' age. The aim of this analysis was to describe patterns of aortic valve replacement (AVR) use in European countries stratified by age. Methods: Procedure volume data for AVR, including surgical aortic valve replacement (sAVR) and transcatheter aortic valve implantation (TAVI), for the years 2015–2020 were obtained from national databases for twelve European countries (Austria, the Czech Republic, Denmark, England, Finland, France, Germany, Norway, Poland, Spain, Sweden, and Switzerland). Procedure volumes were reported by patient age (<50 years, 5-year age groups between 50 and 85 years, and ≥85 years). Patients per million (PPM) population undergoing AVR each year were calculated using population estimates from Eurostat. Results: AVR PPM varied widely between countries, from 508 PPM in Germany to 174 PPM in Poland in 2020. TAVI rates ranged from 61% in Switzerland and Finland to 25% in Poland. AVR PPM increased with age to a peak at 80–84 years, after which it decreased again. AVR procedures increased from 2015 to 2019 at an average annual rate of 3.9%. AVR increased more substantially in people aged ≥80 years than in younger age groups; these older age groups accounted for 30% of all AVR procedures in 2015 and 35% in 2019. TAVI accounted for an increasing proportion of all AVR procedures as patient age increased; an overall average of 96% of males and 98% of females aged ≥85 years received TAVI as the treatment modality, although adoption of TAVI differed between countries. Conclusions: There is considerable variation in the rates of AVR use and the adoption of TAVI versus sAVR between European countries. The use of TAVI has increased in recent years, particularly for older patients. [ABSTRACT FROM AUTHOR]

Published
2023
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31. Impact of Enterococci vs. Staphylococci Induced Infective Endocarditis after Transcatheter Aortic Valve Implantation

Author

Gasior, Tomasz, primary, Woitek, Felix J., additional, Schroth, Antonia, additional, Abdel-Wahab, Mohamed, additional, Crusius, Lisa, additional, Haussig, Stephan, additional, Kiefer, Philipp, additional, Scislo, Piotr, additional, Huczek, Zenon, additional, Dabrowski, Maciej, additional, Witkowski, Adam, additional, Olasinska-Wisniewska, Anna, additional, Grygier, Marek, additional, Protasiewicz, Marcin, additional, Hudziak, Damian, additional, Kappert, Utz, additional, Holzhey, David, additional, Wojakowski, Wojtek, additional, Linke, Axel, additional, and Mangner, Norman, additional

Published
2023
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32. Incidence, Clinical Characteristics, and Impact of Absent Echocardiographic Signs in Patients With Infective Endocarditis After Transcatheter Aortic Valve Implantation

Author

Mangner, Norman, primary, Panagides, Vassili, additional, del Val, David, additional, Abdel-Wahab, Mohamed, additional, Crusius, Lisa, additional, Durand, Eric, additional, Ihlemann, Nikolaj, additional, Urena, Marina, additional, Pellegrini, Costanza, additional, Giannini, Francesco, additional, Gasior, Tomasz, additional, Wojakowski, Wojtek, additional, Landt, Martin, additional, Auffret, Vincent, additional, Sinning, Jan-Malte, additional, Cheema, Asim N, additional, Nombela-Franco, Luis, additional, Chamandi, Chekrallah, additional, Campelo-Parada, Francisco, additional, Munoz-Garcia, Erika, additional, Herrmann, Howard C, additional, Testa, Luca, additional, Kim, Won-Keun, additional, Eltchaninoff, Helene, additional, Søndergaard, Lars, additional, Himbert, Dominique, additional, Husser, Oliver, additional, Latib, Azeem, additional, Le Breton, Hervé, additional, Servoz, Clement, additional, Gervais, Philippe, additional, Côté, Mélanie, additional, Thiele, Holger, additional, Holzhey, David, additional, Linke, Axel, additional, and Rodés-Cabau, Josep, additional

Published
2022
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33. TCT-311 Complicated Plaques Prevail in Longer Lesions of DM Patients, but Lesions’ Length Does Not Impact DM Patients’ Prognosis: Data From COMBINE OCT-FFR Trial

Author

Roleder, Tomasz, primary, Berta, Balazs, additional, Ijsselmuiden, Alexander, additional, Alfonso, Fernando, additional, García-Guimaraes, Marcos, additional, Kauer, Floris, additional, Hermanides, Rik, additional, De Luca, Giuseppe, additional, Kennedy, Mark, additional, Malinowski, Krzysztof, additional, Wojakowski, Wojtek, additional, and Kedhi, Elvin, additional

Published
2022
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34. TCT-370 Negative Compared to Positive Echocardiographic Imaging of Infective Endocarditis After Transcatheter Aortic Valve Implantation

Author

Mangner, Norman, primary, Abdel-Wahab, Mohamed, additional, Gasior, Tomasz, additional, Crusius, Lisa, additional, Woitek, Felix, additional, Haussig, Stephan, additional, Stachel, Georg, additional, Schroth, Antonia, additional, Kiefer, Philipp, additional, Kappert, Utz, additional, Wojakowski, Wojtek, additional, Holzhey, David, additional, and Linke, Axel, additional

Published
2022
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35. 2022 ESC Guidelines on cardiovascular assessment and management of patients undergoing non-cardiac surgery Developed by the task force for cardiovascular assessment and management of patients undergoing non-cardiac surgery of the European Society of Cardiology (ESC) Endorsed by the European Society of Anaesthesiology and Intensive Care (ESAIC)

Author

Halvorsen, Sigrun, Mehilli, Julinda, Cassese, Salvatore, Hall, Trygve S., Abdelhamid, Magdy, Barbato, Emanuele, De Hert, Stefan, de Laval, Ingrid, Geisler, Tobias, Hinterbuchner, Lynne, Ibanez, Borja, Lenarczyk, Radoslaw, Mansmann, Ulrich R., McGreavy, Paul, Mueller, Christian, Muneretto, Claudio, Niessner, Alexander, Potpara, Tatjana S., Ristic, Arsen, Sade, L. Elif, Schirmer, Henrik, Schuepke, Stefanie, Sillesen, Henrik, Skulstad, Helge, Torracca, Lucia, Tutarel, Oktay, Van der Meer, Peter, Wojakowski, Wojtek, Zacharowski, Kai, Cardiovascular Centre (CVC), and Restoring Organ Function by Means of Regenerative Medicine (REGENERATE)

Subjects
PERIOPERATIVE BETA-BLOCKADE, Anti-thrombotic therapy, infarction, Peri-operative cardiac management, Post-operative cardiac surveillance, NONSTEROIDAL ANTIINFLAMMATORY DRUGS, Guidelines, Peri-operative myocardial injury, Pre-operative cardiac testing, CONGENITAL HEART-DISEASE, Non-cardiac surgery, Peri-operative beta-blockers, IMPLANTABLE CARDIOVERTER-DEFIBRILLATORS, POSTOPERATIVE ATRIAL-FIBRILLATION, Peri-operative treatment of arrhythmias, DIRECT ORAL ANTICOAGULANTS, CORONARY-ARTERY-DISEASE, Pre-operative treatment of valvular disease, Pre-operative cardiac risk assessment, HIGH-RISK PATIENTS, DOBUTAMINE STRESS ECHOCARDIOGRAPHY, Biomarkers, Pre-operative coronary artery revascularization, DUAL-ANTIPLATELET THERAPY
Published
2022

36. Corrigendum to: 2021 ESC/EACTS Guidelines for the management of valvular heart disease

Author

Beyersdorf, Friedhelm, Vahanian, Alec, Milojevic, Milan, Praz, Fabien, Baldus, Stephan, Bauersachs, Johann, Capodanno, Davide, Conradi, Lenard, De Bonis, Michele, De Paulis, Ruggero, Delgado, Victoria, Freemantle, Nick, Gilard, Martine, Haugaa, Kristina H, Jeppsson, Anders, Jüni, Peter, Pierard, Luc, Prendergast, Bernard D, Sádaba, J Rafael, Tribouilloy, Christophe, Wojakowski, Wojtek, Beyersdorf, Friedhelm, Vahanian, Alec, Milojevic, Milan, Praz, Fabien, Baldus, Stephan, Bauersachs, Johann, Capodanno, Davide, Conradi, Lenard, De Bonis, Michele, De Paulis, Ruggero, Delgado, Victoria, Freemantle, Nick, Gilard, Martine, Haugaa, Kristina H, Jeppsson, Ander, Jüni, Peter, Pierard, Luc, Prendergast, Bernard D, Sádaba, J Rafael, Tribouilloy, Christophe, and Wojakowski, Wojtek

Subjects
Pulmonary and Respiratory Medicine, Surgery, General Medicine, Cardiology and Cardiovascular Medicine
Published
2022

37. Erratum to: 2021 ESC/EACTS Guidelines for the management of valvular heart disease

Author

Beyersdorf, Friedhelm, Vahanian, Alec, Milojevic, Milan, Praz, Fabien, Baldus, Stephan, Bauersachs, Johann, Capodanno, Davide, Conradi, Lenard, De Bonis, Michele, De Paulis, Ruggero, Delgado, Victoria, Freemantle, Nick, Gilard, Martine, Haugaa, Kristina H, Jeppsson, Anders, Jüni, Peter, Pierard, Luc, Prendergast, Bernard D, Sádaba, J Rafael, Tribouilloy, Christophe, Wojakowski, Wojtek, Beyersdorf, Friedhelm, Vahanian, Alec, Milojevic, Milan, Praz, Fabien, Baldus, Stephan, Bauersachs, Johann, Capodanno, Davide, Conradi, Lenard, De Bonis, Michele, De Paulis, Ruggero, Delgado, Victoria, Freemantle, Nick, Gilard, Martine, Haugaa, Kristina H, Jeppsson, Ander, Jüni, Peter, Pierard, Luc, Prendergast, Bernard D, Sádaba, J Rafael, Tribouilloy, Christophe, and Wojakowski, Wojtek

Subjects
Pulmonary and Respiratory Medicine, Surgery, General Medicine, Cardiology and Cardiovascular Medicine
Published
2022

38. Predictors of Device-Related Thrombus Following Percutaneous Left Atrial Appendage Occlusion

Author

Fauchier, Grégoire, Bisson, Arnaud, Bodin, Alexandre, Herbert, Julien, Semaan, Carl, Angoulvant, Denis, Ducluzeau, Pierre Henri, Lip, Gregory, Fauchier, Laurent, Deharo, Pierre, Cuisset, Thomas, Lacour, Thibaud, Etienne, Christophe Saint, Jaussaud, Nicolas, Morera, Pierre, Spychaj, Jean-Charles, Porto, Alizée, Collart, Frederic, Theron, Alexis, Bernard, Anne, Bourguignon, Thierry, Simard, Trevor, Jung, Richard, Lehenbauer, Kyle, Piayda, Kerstin, Pracoń, Radoslaw, Jackson, Gregory, Flores-Umanzor, Eduardo, Faroux, Laurent, Korsholm, Kasper, Chun, Julian K.R., Chen, Shaojie, Maarse, Moniek, Montrella, Kristi, Chaker, Zakeih, Spoon, Jocelyn, Pastormerlo, Luigi, Meincke, Felix, Sawant, Abhishek, Moldovan, Carmen, Qintar, Mohammed, Aktas, Mehmet, Branca, Luca, Radinovic, Andrea, Ram, Pradhum, El-Zein, Rayan, Flautt, Thomas, Ding, Wern Yew, Sayegh, Bassel, Benito-González, Tomás, Lee, Oh-Hyun, Badejoko, Solomon, Paitazoglou, Christina, Karim, Nabeela, Zaghloul, Ahmed, Agrawal, Himanshu, Kaplan, Rachel, Alli, Oluseun, Ahmed, Aamir, Suradi, Hussam, Knight, Bradley, Alla, Venkata, Panaich, Sidakpal, Wong, Tom, Bergmann, Martin, Chothia, Rashaad, Kim, Jung-Sun, Pérez de Prado, Armando, Bazaz, Raveen, Gupta, Dhiraj, Valderrabano, Miguel, Sanchez, Carlos, El Chami, Mikhael, Mazzone, Patrizio, Adamo, Marianna, Ling, Fred, Wang, Dee Dee, O’neill, William, Wojakowski, Wojtek, Pershad, Ashish, Berti, Sergio, Spoon, Daniel, Kawsara, Akram, Jabbour, George, Boersma, Lucas V.A., Schmidt, Boris, Nielsen-Kudsk, Jens Erik, Rodés-Cabau, Josep, Freixa, Xavier, Ellis, Christopher, Demkow, Marcin, Sievert, Horst, Main, Michael, Hibbert, Benjamin, Holmes, David, Alkhouli, Mohamad, Centre Hospitalier Régional Universitaire de Tours (CHRU Tours), CHU Trousseau [Tours], Éducation Éthique Santé EA 7505 (EES), Université de Tours (UT), EA4245 - Transplantation, Immunologie, Inflammation [Tours] (T2i), University of Liverpool, Aalborg University [Denmark] (AAU), Centre recherche en CardioVasculaire et Nutrition = Center for CardioVascular and Nutrition research (C2VN), Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Hôpital de la Timone [CHU - APHM] (TIMONE), Nutrition, obésité et risque thrombotique (NORT), Institut National de la Recherche Agronomique (INRA)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM), CHU Marseille, Département de Cardiologie [Hôpital de la Timone - APHM], Assistance Publique - Hôpitaux de Marseille (APHM)- Hôpital de la Timone [CHU - APHM] (TIMONE), Institut de neurophysiopathologie (INP), Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS), University of Ottawa [Ottawa], Université Laval [Québec] (ULaval), National Institute for Research and Development in Microtechnologies (IMT-Bucharest), Graduate School, Cardiology, and ACS - Heart failure & arrhythmias

Subjects
Male, Cardiac Catheterization, Time Factors, Percutaneous, left atrial appendage occlusion, Septal Occluder Device, medicine.medical_treatment, Transesophageal, [SHS]Humanities and Social Sciences, Pulmonary vein, Postoperative Complications, Risk Factors, Interquartile range, Atrial Fibrillation, Registries, Embolization, ComputingMilieux_MISCELLANEOUS, Watchman, Incidence, Atrial fibrillation, Europe, Survival Rate, Treatment Outcome, Echocardiography, Cardiology, Female, Watchman FLX, Cardiology and Cardiovascular Medicine, medicine.medical_specialty, Heart Diseases, ACP, Amplatzer cardiac plug, Amulet, DRT, LAAO, device-related thrombus, Aged, Atrial Appendage, Echocardiography, Transesophageal, Follow-Up Studies, Humans, Thrombosis, Left atrial appendage occlusion, Internal medicine, medicine, Risk factor, Thrombus, business.industry, medicine.disease, business
Abstract

Background: Device-related thrombus (DRT) has been considered an Achilles’ heel of left atrial appendage occlusion (LAAO). However, data on DRT prediction remain limited. Objectives: This study constructed a DRT registry via a multicenter collaboration aimed to assess outcomes and predictors of DRT. Methods: Thirty-seven international centers contributed LAAO cases with and without DRT (device-matched and temporally related to the DRT cases). This study described the management patterns and mid-term outcomes of DRT and assessed patient and procedural predictors of DRT. Results: A total of 711 patients (237 with and 474 without DRT) were included. Follow-up duration was similar in the DRT and no-DRT groups, median 1.8 years (interquartile range: 0.9-3.0 years) versus 1.6 years (interquartile range: 1.0-2.9 years), respectively (P = 0.76). DRTs were detected between days 0 to 45, 45 to 180, 180 to 365, and >365 in 24.9%, 38.8%, 16.0%, and 20.3% of patients. DRT presence was associated with a higher risk of the composite endpoint of death, ischemic stroke, or systemic embolization (HR: 2.37; 95% CI, 1.58-3.56; P < 0.001) driven by ischemic stroke (HR: 3.49; 95% CI: 1.35-9.00; P = 0.01). At last known follow-up, 25.3% of patients had DRT. Discharge medications after LAAO did not have an impact on DRT. Multivariable analysis identified 5 DRT risk factors: hypercoagulability disorder (odds ratio [OR]: 17.50; 95% CI: 3.39-90.45), pericardial effusion (OR: 13.45; 95% CI: 1.46-123.52), renal insufficiency (OR: 4.02; 95% CI: 1.22-13.25), implantation depth >10 mm from the pulmonary vein limbus (OR: 2.41; 95% CI: 1.57-3.69), and non-paroxysmal atrial fibrillation (OR: 1.90; 95% CI: 1.22-2.97). Following conversion to risk factor points, patients with ≥2 risk points for DRT had a 2.1-fold increased risk of DRT compared with those without any risk factors. Conclusions: DRT after LAAO is associated with ischemic events. Patient- and procedure-specific factors are associated with the risk of DRT and may aid in risk stratification of patients referred for LAAO.

Published
2021

39. Prosthesis-patient mismatch following transcatheter aortic valve replacement for degenerated transcatheter aortic valves: the TRANSIT-PPM international project

Author

Testa, Luca, primary, Casenghi, Matteo, additional, Criscione, Enrico, additional, Van Mieghem, Nicolas M., additional, Tchétché, Didier, additional, Asgar, Anita W., additional, De Backer, Ole, additional, Latib, Azeem, additional, Reimers, Bernhard, additional, Stefanini, Giulio, additional, Trani, Carlo, additional, Giannini, Francesco, additional, Bartorelli, Antonio, additional, Wojakowski, Wojtek, additional, Dabrowski, Maciej, additional, Jagielak, Dariusz, additional, Banning, Adrian P., additional, Kharbanda, Rajesh, additional, Moreno, Raul, additional, Schofer, Joachim, additional, Brinkmann, Christina, additional, van Royen, Niels, additional, Pinto, Duane, additional, Serra, Antoni, additional, Segev, Amit, additional, Giordano, Arturo, additional, Brambilla, Nedy, additional, Agnifili, Mauro, additional, Rubbio, Antonio Popolo, additional, Squillace, Mattia, additional, Oreglia, Jacopo, additional, Tanja, Rudolph, additional, McCabe, James M., additional, Abizaid, Alexander, additional, Voskuil, Michiel, additional, Teles, Rui, additional, Zoccai, Giuseppe Biondi, additional, Sondergaard, Lars, additional, and Bedogni, Francesco, additional

Published
2022
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40. 2021 ESC/EACTS Guidelines for the management of valvular heart disease: Developed by the Task Force for the management of valvular heart disease of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS)

Author

Vahanian, Alec, primary, Beyersdorf, Friedhelm, additional, Praz, Fabien, additional, Milojevic, Milan, additional, Baldus, Stephan, additional, Bauersachs, Johann, additional, Capodanno, Davide, additional, Conradi, Lenard, additional, De Bonis, Michele, additional, De Paulis, Ruggero, additional, Delgado, Victoria, additional, Freemantle, Nick, additional, Gilard, Martine, additional, Haugaa, Kristina H., additional, Jeppsson, Anders, additional, Jüni, Peter, additional, Pierard, Luc, additional, Prendergast, Bernard D., additional, Sádaba, J. Rafael, additional, Tribouilloy, Christophe, additional, and Wojakowski, Wojtek, additional

Published
2022
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42. The effect of intracoronary infusion of bone marrow‐derived mononuclear cells on all‐cause mortality in acute myocardial infarction: rationale and design of the BAMI trial

Author

Mathur, Anthony, Arnold, Roman, Assmus, Birgit, Bartunek, Jozef, Belmans, Ann, Bönig, Halvard, Crea, Filippo, Dimmeler, Stefanie, Dowlut, Sheik, Fernández‐Avilés, Francisco, Galiñanes, Manuel, Garcia‐Dorado, David, Hartikainen, Juha, Hill, Jonathan, Hogardt‐Noll, Annette, Homsy, Christian, Janssens, Stefan, Kala, Petr, Kastrup, Jens, Martin, John, Menasche, Philippe, Miklik, Roman, Mozid, Abdul, San Román, J. Alberto, Sanz‐Ruiz, Ricardo, Tendera, Michal, Wojakowski, Wojtek, Ylä‐Herttuala, Seppo, and Zeiher, Andreas

Published
2017
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43. Effect of allogeneic adipose tissue‐derived mesenchymal stromal cell treatment in chronic ischaemic heart failure with reduced ejection fraction – the SCIENCE trial.

Author

Qayyum, Abbas Ali, van Klarenbosch, Bas, Frljak, Sabina, Cerar, Andraz, Poglajen, Gregor, Traxler‐Weidenauer, Denise, Nadrowski, Pawel, Paitazoglou, Christina, Vrtovec, Bojan, Bergmann, Martin W., Chamuleau, Steven A. J., Wojakowski, Wojtek, Gyöngyösi, Mariann, Kraaijeveld, Adriaan, Hansen, Kristian Schultz, Vrangbæk, Karsten, Jørgensen, Erik, Helqvist, Steffen, Joshi, Francis Richard, and Johansen, Ellen Mønsted

Subjects
BRAIN natriuretic factor, STROMAL cells, HEART failure, VENTRICULAR ejection fraction, ADIPOSE tissue diseases, CARDIAC patients
Abstract

Aims: The aim of the SCIENCE trial was to investigate whether a single treatment with direct intramyocardial injections of adipose tissue‐derived mesenchymal stromal cells (CSCC_ASCs) was safe and improved cardiac function in patients with chronic ischaemic heart failure with reduced ejection fraction (HFrEF). Methods and results: The study was a European multicentre, double‐blind, placebo‐controlled phase II trial using allogeneic CSCC_ASCs from healthy donors or placebo (2:1 randomization). Main inclusion criteria were New York Heart Association (NYHA) class II–III, left ventricular ejection fraction (LVEF) <45%, and N‐terminal pro‐B‐type natriuretic peptide (NT‐proBNP) levels >300 pg/ml. CSCC_ASCs or placebo (isotonic saline) were injected directly into viable myocardium. The primary endpoint was change in left ventricular end‐systolic volume (LVESV) at 6‐month follow‐up measured by echocardiography. A total of 133 symptomatic HFrEF patients were included. The treatment was safe without any drug‐related severe adverse events or difference in cardiac‐related adverse events during a 3‐year follow‐up period. There were no significant differences between groups during follow‐up in LVESV (0.3 ± 5.0 ml, p = 0.945), nor in secondary endpoints of left ventricular end‐diastolic volume (−2.0 ± 6.0 ml, p = 0.736) and LVEF (−1.6 ± 1.0%, p = 0.119). The NYHA class improved slightly within the first year in both groups without any difference between groups. There were no changes in 6‐min walk test, NT‐proBNP, C‐reactive protein or quality of life the first year in any groups. Conclusion: The SCIENCE trial demonstrated safety of intramyocardial allogeneic CSCC_ASC therapy in patients with chronic HFrEF. However, it was not possible to improve the pre‐defined endpoints and induce restoration of cardiac function or clinical symptoms. [ABSTRACT FROM AUTHOR]

Published
2023
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44. Incidence, Clinical Characteristics, and Impact of Absent Echocardiographic Signs in Patients With Infective Endocarditis After Transcatheter Aortic Valve Implantation.

Author

Mangner, Norman, Panagides, Vassili, Val, David del, Abdel-Wahab, Mohamed, Crusius, Lisa, Durand, Eric, Ihlemann, Nikolaj, Urena, Marina, Pellegrini, Costanza, Giannini, Francesco, Gasior, Tomasz, Wojakowski, Wojtek, Landt, Martin, Auffret, Vincent, Sinning, Jan-Malte, Cheema, Asim N, Nombela-Franco, Luis, Chamandi, Chekrallah, Campelo-Parada, Francisco, and Munoz-Garcia, Erika

Subjects
ECHOCARDIOGRAPHY, EVALUATION of medical care, BLOOD, HEART valve prosthesis implantation, ANEURYSMS, CONFIDENCE intervals, CELL culture, ABSCESSES, MULTIVARIATE analysis, ENDOCARDITIS, DISEASE incidence, REGRESSION analysis, INFECTIVE endocarditis, INFECTION, RISK assessment, COMPARATIVE studies, FALSE aneurysms, STAPHYLOCOCCUS aureus, ODDS ratio, PROSTHESIS-related infections, DISEASE risk factors, EVALUATION
Abstract

Background Echocardiography is the primary imaging modality for diagnosis of infective endocarditis (IE) in prosthetic valve endocarditis (PVE) including IE after transcatheter aortic valve implantation (TAVI). This study aimed to evaluate the characteristics and clinical outcomes of patients with absent compared with evident echocardiographic signs of TAVI-IE. Methods Patients with definite TAVI-IE derived from the Infectious Endocarditis after TAVI International Registry were investigated comparing those with absent and evident echocardiographic signs of IE defined as vegetation, abscess, pseudo-aneurysm, intracardiac fistula, or valvular perforation or aneurysm. Results Among 578 patients, 87 (15.1%) and 491 (84.9%) had absent (IE-neg) and evident (IE-pos) echocardiographic signs of IE, respectively. IE-neg were more often treated via a transfemoral access with a self-expanding device and had higher rates of peri-interventional complications (eg, stroke, major vascular complications) during the TAVI procedure (P <.05 for all). IE-neg had higher rates of IE caused by Staphylococcus aureus (33.7% vs 23.2%; P =.038) and enterococci (37.2% vs 23.8%; P =.009) but lower rates of coagulase-negative staphylococci (4.7% vs 20.0%, P =.001). IE-neg was associated with the same dismal prognosis for in-hospital mortality in a multivariate binary regression analysis (odds ratio: 1.51; 95% confidence interval [CI]:.55–4.12) as well as a for 1-year mortality in Cox regression analysis (hazard ratio: 1.10; 95% CI:.67–1.80). Conclusions Even with negative echocardiographic imaging, patients who have undergone TAVI and presenting with positive blood cultures and symptoms of infection are a high-risk patient group having a reasonable suspicion of IE and the need for an early treatment initiation. [ABSTRACT FROM AUTHOR]

Published
2023
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45. Effect of Vupanorsen on Non–High-Density Lipoprotein Cholesterol Levels in Statin-Treated Patients With Elevated Cholesterol: TRANSLATE-TIMI 70

Author

Bergmark, Brian A., primary, Marston, Nicholas A., additional, Bramson, Candace R., additional, Curto, Madelyn, additional, Ramos, Vesper, additional, Jevne, Alexandra, additional, Kuder, Julia F., additional, Park, Jeong-Gun, additional, Murphy, Sabina A., additional, Verma, Subodh, additional, Wojakowski, Wojtek, additional, Terra, Steven G., additional, Sabatine, Marc S., additional, Wiviott, Stephen D., additional, Carbonneau, Diane, additional, Poulin-Robitaille, Raphael, additional, Wayne, Jeffrey, additional, Lee, Keung, additional, Mujica Trenche, Samuel, additional, Dzongowski, Petros, additional, Gaudet, Daniel, additional, Van, Joanna, additional, Ajani, Dilawar, additional, Bays, Harold, additional, O’Mahony, John, additional, Janas, Adam, additional, Scott, John, additional, Moustafa, Moustafa Ashraf, additional, Ransom, Thomas, additional, Benjamin, Sabrina, additional, Aggarwal, Naresh, additional, Bogdanski, Pawel, additional, Friars, Douglas, additional, Schlosser, Robert, additional, Okopien, Boguslaw, additional, Budhraja, Madhusudan, additional, Feld, Lawrence, additional, Klaff, Leslie, additional, Tellier, Guy, additional, Mazza, Giuseppe, additional, Wierzbicka, Iwona, additional, Jazwinska-Tarnawska, Ewa, additional, Boccalandro, Fernando, additional, Rosenstock, Julio, additional, Marquez, Elizabeth, additional, Barbel-Johnson, Kim, additional, Madziarska, Katarzyna, additional, Heaton, Kenneth, additional, Tardif, Jean-Claude, additional, Rubino, John, additional, Trevino, Miguel, additional, Moriarty, Katie, additional, Gupta, Anil, additional, Wojakowski, Wojciech, additional, Fidelholtz, James, additional, Gupta, Dinesh, additional, Alasaad, Hani, additional, Christensen, Shane, additional, Shah, Parag, additional, Li, Stephanie, additional, Sherman, Mark, additional, Frechette, Andre, additional, Arango, Cecilia, additional, Egan, Alan, additional, Srivastava, Sunny, additional, Bajaj, Archna, additional, Ince Jr, Carlos, additional, and Zurakowski, Aleksander, additional

Published
2022
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46. Safety, Efficacy and Long-Term Outcomes of Patients Treated with the Occlutech Paravalvular Leak Device for Significant Paravalvular Regurgitation

Author

Onorato, Eustaquio Maria, primary, Alamanni, Francesco, additional, Muratori, Manuela, additional, Smolka, Grzegorz, additional, Wojakowski, Wojtek, additional, Pysz, Piotr, additional, Zorinas, Aleksejus, additional, Zakarkaite, Diana, additional, Eltchaninoff, Hélène, additional, Litzer, Pierre-Yves, additional, Godart, François, additional, Calvert, Patrick, additional, Christou, Christos, additional, Mussayev, Abdurashid, additional, Missiroli, Bindo, additional, Buzaev, Igor, additional, Curello, Salvatore, additional, Tesorio, Tullio, additional, and Bartorelli, Antonio Luca, additional

Published
2022
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47. Aortic Valve Replacement Versus Conservative Treatment in Asymptomatic Severe Aortic Stenosis: The AVATAR Trial

Author

Banovic, Marko, primary, Putnik, Svetozar, additional, Penicka, Martin, additional, Doros, Gheorghe, additional, Deja, Marek A., additional, Kockova, Radka, additional, Kotrc, Martin, additional, Glaveckaite, Sigita, additional, Gasparovic, Hrvoje, additional, Pavlovic, Nikola, additional, Velicki, Lazar, additional, Salizzoni, Stefano, additional, Wojakowski, Wojtek, additional, Van Camp, Guy, additional, Nikolic, Serge D., additional, Iung, Bernard, additional, Bartunek, Jozef, additional, Barbato, Emanuele, additional, De Bruyne, Bernard, additional, Casselman, Filip, additional, De Grieck, Ivan, additional, Heyse, Alex, additional, Stockman, Bernard, additional, Vanderheyden, Marc, additional, Van Durme, Frederik, additional, Van Praet, Frank, additional, Wyffels, Eric, additional, Biocina, Bojan, additional, Manola, Sime, additional, Pirk, Jan, additional, Cura-Stura, Erik, additional, Rinaldi, Mauro, additional, Maria De Ferrari, Gaetano, additional, Fava, Antonella, additional, Maria Richiardi, Elena, additional, Celutkiene, Jelena, additional, Filipova, Marta, additional, Ciosek, Joanna, additional, Guzy, Michal, additional, Kurzelowski, Radoslaw, additional, Bjelobrk, Marija, additional, Ilic, Aleksandra, additional, Kovacevic, Mila, additional, Miljkovic, Tatjana, additional, Preveden, Andrej, additional, Srdanovic, Ilija, additional, Aleksandric, Srdjan, additional, Asanin, Milika, additional, Beleslin, Branko, additional, Bojanic, Milica, additional, Boskovic, Nikola, additional, Bosic, Sladjana, additional, Cvetinovic, Natasa, additional, Dedovic, Vladimir, additional, Giga, Vojislav, additional, Jandric, Predrag, additional, Jaukovic, Milena, additional, Jovanovic, Miodrag, additional, Kovacevic-Kuzmanovic, Ana, additional, Loncar, Goran, additional, Manojlovic, Andrea, additional, Matkovic, Milos, additional, Mitrovic, Predrag, additional, Nedeljkovic, Ivana, additional, Nedeljkovic, Milan, additional, Petrovic, Olgica, additional, Ristic, Arsen, additional, Seper, Mirjana, additional, Simic, Dragan, additional, Stankovic, Sanja, additional, Stojkovic, Sinisa, additional, Vukcevic, Vladan, additional, and Zivic, Katarina, additional

Published
2022
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48. 2021 ESC/EACTS Guidelines for the management of valvular heart disease: Developed by the Task Force for the management of valvular heart disease of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS)

Author

Vahanian, Alec, Beyersdorf, Friedhelm, Praz, Fabien, Milojevic, Milan, Baldus, Stephan, Bauersachs, Johann, Capodanno, Davide, Conradi, Lenard, De Bonis, Michele, De Paulis, Ruggero, Delgado, Victoria, Freemantle, Nick, Gilard, Martine, Haugaa, Kristina H., Jeppsson, Anders, Pierard, Luc, Prendergast, Bernard D., Sadaba, J. Rafael, Tribouilloy, Christophe, Wojakowski, Wojtek, and Cardiothoracic Surgery

Published
2022

49. 2021 ESC/EACTS Guidelines for the management of valvular heart disease

Author

Vahanian, Alec, primary, Beyersdorf, Friedhelm, additional, Praz, Fabien, additional, Milojevic, Milan, additional, Baldus, Stephan, additional, Bauersachs, Johann, additional, Capodanno, Davide, additional, Conradi, Lenard, additional, De Bonis, Michele, additional, De Paulis, Ruggero, additional, Delgado, Victoria, additional, Freemantle, Nick, additional, Haugaa, Kristina Haugaa, additional, Jeppsson, Anders, additional, Jüni, Peter, additional, Pierard, Luc, additional, Prendergast, Bernard Prendergast, additional, Sádaba, J. Sádaba, additional, Tribouilloy, Christophe, additional, and Wojakowski, Wojtek, additional

Published
2022
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50. Perivalvular Extension of Infective Endocarditis After Transcatheter Aortic Valve Replacement

Author

Panagides, Vassili, primary, del Val, David, additional, Abdel-Wahab, Mohamed, additional, Mangner, Norman, additional, Durand, Eric, additional, Ihlemann, Nikolaj, additional, Urena, Marina, additional, Pellegrini, Costanza, additional, Giannini, Francesco, additional, Gasior, Tomasz, additional, Wojakowski, Wojtek, additional, Landt, Martin, additional, Auffret, Vincent, additional, Sinning, Jan Malte, additional, Cheema, Asim N, additional, Nombela-Franco, Luis, additional, Chamandi, Chekrallah, additional, Campelo-Parada, Francisco, additional, Munoz-Garcia, Erika, additional, Herrmann, Howard C, additional, Testa, Luca, additional, Kim, Won Keun, additional, Castillo, Juan Carlos, additional, Alperi, Alberto, additional, Tchetche, Didier, additional, Bartorelli, Antonio L, additional, Kapadia, Samir, additional, Stortecky, Stefan, additional, Amat-Santos, Ignacio, additional, Wijeysundera, Harindra C, additional, Lisko, John, additional, Gutiérrez-Ibanes, Enrique, additional, Serra, Vicenç, additional, Salido, Luisa, additional, Alkhodair, Abdullah, additional, Livi, Ugolino, additional, Chakravarty, Tarun, additional, Lerakis, Stamatios, additional, Vilalta, Victoria, additional, Regueiro, Ander, additional, Romaguera, Rafael, additional, Kappert, Utz, additional, Barbanti, Marco, additional, Masson, Jean Bernard, additional, Maes, Frédéric, additional, Fiorina, Claudia, additional, Miceli, Antonio, additional, Kodali, Susheel, additional, Ribeiro, Henrique B, additional, Mangione, Jose Armando, additional, Sandoli de Brito, Fabio, additional, Actis Dato, Guglielmo Mario, additional, Rosato, Francesco, additional, Ferreira, Maria Cristina, additional, Correia de Lima, Valter, additional, Colafranceschi, Alexandre Siciliano, additional, Abizaid, Alexandre, additional, Marino, Marcos Antonio, additional, Esteves, Vinicius, additional, Andrea, Julio, additional, Godinho, Roger R, additional, Alfonso, Fernando, additional, Eltchaninoff, Helene, additional, Søndergaard, Lars, additional, Himbert, Dominique, additional, Husser, Oliver, additional, Latib, Azeem, additional, Le Breton, Hervé, additional, Servoz, Clement, additional, Pascual, Isaac, additional, Siddiqui, Saif, additional, Olivares, Paolo, additional, Hernandez-Antolin, Rosana, additional, Webb, John G, additional, Sponga, Sandro, additional, Makkar, Raj, additional, Kini, Annapoorna S, additional, Boukhris, Marouane, additional, Gervais, Philippe, additional, Linke, Axel, additional, Crusius, Lisa, additional, Holzhey, David, additional, and Rodés-Cabau, Josep, additional

Published
2021
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