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3. Novel anemia therapies in chronic kidney disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference

Author

Afsar, Baris, Akizawa, Tadao, Anker, Stefan D., Arici, Mustafa, Babitt, Jodie L., Barratt, Jonathan, Berns, Jeffrey S., Besarab, Anatole, Bhandari, Sunil, Brown, Christopher, Cases, Aleix, Chertow, Glenn M., Delgado, Cynthia, Drüeke, Tillman B., Fishbane, Steven, Gómez, Rafael, Grams, Morgan E., Hamano, Takayuki, Hao, Chuan-Ming, Hsu, Raymond K., Iseki, Kunitoshi, Jordans, Isabelle, Lerma, Edgar V., Locatelli, Francesco, Macdougall, Iain C., Małyszko, Jolanta, Maxwell, Patrick, McMahon, Lawrence P., Obrador, Gregorio T., Ostermann, Marlies, Pecoits-Filho, Roberto, Perwad, Farzana, Roger, Simon D., Singh, Ajay K., Solá, Laura, Spinowitz, Bruce S., Sugahara, Mai, Takahashi, Toshiyuki, Tanaka, Mototsugu, Tanaka, Tetsuhiro, Tarng, Der-Cherng, Tonelli, Marcello, Tsukamoto, Yusuke, Walther, Carl P., Yee-Moon Wang, Angela, Kong, Hong, Warady, Bradley A., Webster, Angela C., Weir, Matthew R., Wish, Jay B., Wong, Muh Geot, Ku, Elaine, Del Vecchio, Lucia, Eckardt, Kai-Uwe, Haase, Volker H., Johansen, Kirsten L., Nangaku, Masaomi, Tangri, Navdeep, Waikar, Sushrut S., Więcek, Andrzej, Cheung, Michael, Jadoul, Michel, Winkelmayer, Wolfgang C., and Wheeler, David C.

Published
2023
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13. Introduction of Biosimilar Therapeutics Into Nephrology Practice in the United States: Report of a Scientific Workshop Sponsored by the National Kidney Foundation

Author

Wish, Jay B, Charytan, Chaim, Chertow, Glenn M, Kalantar-Zadeh, Kamyar, Kliger, Alan S, Rubin, Robert J, Yee, Jerry, and Fishbane, Steven

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Kidney Disease, Biomedical Research, Biosimilar Pharmaceuticals, Congresses as Topic, Drug Utilization, Humans, Kidney Diseases, Nephrology, Practice Guidelines as Topic, United States, Biosimilar, biologic, erythropoietin analogue, dialysis, regulatory, therapeutic equivalency, reference agent, drug approval, safety, efficacy, cost, anemia, nephrology, end-stage renal disease, pharmacovigilance, interchangeability, Public Health and Health Services, Urology & Nephrology, Clinical sciences
Abstract

Biosimilars are biologic medicines highly similar to the reference product with no meaningful clinical differences in terms of safety, purity, and potency. All biologic medicines are produced by living cells, resulting in an inherent heterogeneity in their higher order structures and post-translational modifications. In 2010, the US Congress enacted legislation to streamline the approval process for biosimilars of products losing patent protection, with the goal of decreasing costs and improving patient access to therapeutically important but expensive biologic agents. In 2015, the US Food and Drug Administration approved the first biosimilar agent through this pathway. Approval of additional biosimilar agents in the United States, including those used by nephrologists, is anticipated. Given the relative lack of knowledge regarding biosimilars and their approval process and a lack of trust by the nephrology community regarding their safety and efficacy, the National Kidney Foundation conducted a symposium, Introduction of Biosimilar Therapeutics Into Nephrology Practice in the U.S., September 17 to 18, 2015. Issues related to manufacturing, the regulatory approval process, interchangeability, substitution/switching, nomenclature, and clinician and patient awareness and acceptance were examined. This report summarizes the main discussions at the symposium, highlights several controversies, and makes recommendations related to public policy, professional and patient education, and research needs.

Published
2016

14. New Options for Iron Supplementation in Maintenance Hemodialysis Patients.

Author

Vaziri, Nosratola D, Kalantar-Zadeh, Kamyar, and Wish, Jay B

Subjects
Humans, Kidney Failure, Chronic, Anemia, Iron, Trace Elements, Transferrin, Hemoglobins, Erythropoietin, Hematinics, Dialysis Solutions, Drug Delivery Systems, Renal Dialysis, Comparative Effectiveness Research, Administration, Intravenous, Long Term Adverse Effects, Iron supplementation, anemia of chronic kidney disease, end-stage renal disease, ferric citrate, ferric pyrophosphate citrate, hemodialysis, iron dosing, serum ferritin, transferrin saturation, Kidney Failure, Chronic, Administration, Intravenous, Urology & Nephrology, Clinical Sciences, Public Health and Health Services
Abstract

End-stage renal disease results in anemia caused by shortened erythrocyte survival, erythropoietin deficiency, hepcidin-mediated impairment of intestinal absorption and iron release, recurrent blood loss, and impaired responsiveness to erythropoiesis-stimulating agents (ESAs). Iron malabsorption renders oral iron products generally ineffective, and intravenous (IV) iron supplementation is required in most patients receiving maintenance hemodialysis (HD). IV iron is administered at doses far exceeding normal intestinal iron absorption. Moreover, by bypassing physiologic safeguards, indiscriminate use of IV iron overwhelms transferrin, imposing stress on the reticuloendothelial system that can have long-term adverse consequences. Unlike conventional oral iron preparations, ferric citrate has recently been shown to be effective in increasing serum ferritin, hemoglobin, and transferrin saturation values while significantly reducing IV iron and ESA requirements in patients treated with HD. Ferric pyrophosphate citrate is a novel iron salt delivered by dialysate; by directly reaching transferrin, its obviates the need for storing administered iron and increases transferrin saturation without increasing serum ferritin levels. Ferric pyrophosphate citrate trials have demonstrated effective iron delivery and stable hemoglobin levels with significant reductions in ESA and IV iron requirements. To date, the long-term safety of using these routes of iron administration in patients receiving HD has not been compared to IV iron and therefore awaits future investigations.

Published
2016

21. Contributors

Author

Agarwal, Rajiv, primary, Alfaadhel, Talal, additional, Andersen, Martin J., additional, Asplin, John Robert, additional, Avasare, Rupali S., additional, Bakris, George L., additional, Bansal, Amar D., additional, Baxi, Pravir V., additional, Berkoben, Michael, additional, Bieber, Scott D., additional, Buchkremer, Florian, additional, Burgner, Anna Marie, additional, Byrd, James Brian, additional, Cattran, Daniel, additional, Choudhury, Devasmita, additional, Granado, Rolando Claure-Del, additional, Denker, Bradley M., additional, Derebail, Vimal K., additional, Desnick, Robert J., additional, Lullo, Luca di, additional, Duronville, John V., additional, Eknoyan, Garabed, additional, Kateb, Mina El, additional, Elliott, William J., additional, Ennis, Jennifer L., additional, Fervenza, Fernando C., additional, Figlin, Robert A., additional, Galvin, Zita, additional, Garimella, Pranav S., additional, Gipson, Debbie S., additional, Gipson, Patrick E., additional, Goldfarb, David S., additional, Greenberg, Arthur, additional, Haller, Hermann, additional, Hiremath, Swapnil, additional, Horwitz, Edward J., additional, Hou, Susan, additional, Inker, Lesley A., additional, Irazabal, Maria V., additional, Irish, Ashley Bruce, additional, Jhaveri, Kenar D., additional, Jefferson, Jonathan Ashley, additional, Kalantar-Zadeh, Kamyar, additional, Kamil, Elaine S., additional, Kenny, Jon-Emile S., additional, Khoury, Charbel C., additional, Kohli, Jatinder, additional, Kovalik, Eugene C., additional, Kovesdy, Csaba P., additional, Kupin, Warren, additional, Lehrich, Ruediger W., additional, Lerma, Edgar V., additional, Levi, Moshe, additional, Lockridge, Joseph L., additional, Lopez, Jennifer, additional, Macedo, Etienne, additional, Mehrotra, Rajnish, additional, Mehta, Ravindra L., additional, Nachman, Patrick H., additional, Nadai, Carol, additional, Negrea, Lavinia Aura, additional, Nicolle, Lindsay E., additional, Norris, Keith C., additional, Novakovic, Alexander, additional, Olyaei, Ali J., additional, Pal, Sumanta Kumar, additional, Palevsky, Paul M., additional, Patel, Ami M., additional, Patney, Vikram, additional, Perazella, Mark A., additional, Pham, Phuong-Chi T., additional, Pham, Phuong-Thu T., additional, Pryor, Joseph B., additional, S. Ram, C. Venkata, additional, Rahman, MD, Mahboob, additional, Reisinger, Nathaniel, additional, Rocco, Michael V., additional, Ronco, Claudio, additional, Rosenberg, Mark E., additional, Rosner, Mitchell H., additional, Rudnick, Michael R., additional, Sabath, Ernesto, additional, Sarnak, Mark J., additional, Schell, Jane O., additional, Seay, N. Winn, additional, Sedor, John R., additional, Sethi, Akash Nair, additional, Shah, Anuja, additional, Shah, Lori, additional, Sherer, Benjamin A., additional, Singh, Harpreet, additional, Sinniah, Rajalingam, additional, Sloand, James A., additional, Sparks, Matthew A., additional, Sprague, Stuart M., additional, Steigerwalt, Susan Patricia, additional, Sternlicht, Hillel, additional, Stoller, Marshall L., additional, Thomas, Beje, additional, Toka, Hakan R., additional, Topf, Joel M., additional, Torres, Vicente E., additional, Trachtman, Howard, additional, Traynor, Carol, additional, Tucker, Bryan M., additional, Vogt, Beth A., additional, Wanchoo, Rimda, additional, Weir, Matthew R., additional, Whaley-Connell, Adam, additional, Whittier, William L., additional, Wish, Jay B., additional, Wong, Florence, additional, Wymer, David C., additional, Wymer, David T.G., additional, and Zand, Ladan, additional

Published
2019
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23. Novel Anemia Therapies in CKD: Conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference

Author

Ku, Elaine, primary, Del Vecchio, Lucia, additional, Eckardt, Kai-Uwe, additional, Haase, Volker H., additional, Johansen, Kirsten L., additional, Nangaku, Masaomi, additional, Tangri, Navdeep, additional, Waikar, Sushrut S., additional, Więcek, Andrzej, additional, Cheung, Michael, additional, Jadoul, Michel, additional, Winkelmayer, Wolfgang C., additional, Wheeler, David C., additional, Afsar, Baris, additional, Akizawa, Tadao, additional, Anker, Stefan D., additional, Arici, Mustafa, additional, Babitt, Jodie L., additional, Barratt, Jonathan, additional, Berns, Jeffrey S., additional, Besarab, Anatole, additional, Bhandari, Sunil, additional, Brown, Christopher, additional, Cases, Aleix, additional, Chertow, Glenn M., additional, Delgado, Cynthia, additional, Drüeke, Tillman B., additional, Fishbane, Steven, additional, Gómez, Rafael, additional, Grams, Morgan E., additional, Hamano, Takayuki, additional, Hao, Chuan-Ming, additional, Hsu, Raymond K., additional, Iseki, Kunitoshi, additional, Jordans, Isabelle, additional, Lerma, Edgar V., additional, Locatelli, Francesco, additional, Macdougall, Iain C., additional, Małyszko, Jolanta, additional, Maxwell, Patrick, additional, McMahon, Lawrence P., additional, Obrador, Gregorio T., additional, Ostermann, Marlies, additional, Pecoits-Filho, Roberto, additional, Perwad, Farzana, additional, Roger, Simon D., additional, Singh, Ajay K., additional, Solá, Laura, additional, Spinowitz Mai Sugahara, Bruce S., additional, Takahashi, Toshiyuki, additional, Tanaka, Mototsugu, additional, Tanaka, Tetsuhiro, additional, Tarng, Der-Cherng, additional, Tonelli, Marcello, additional, Tsukamoto, Yusuke, additional, Walther, Carl P., additional, Yee-Moon Wang, Angela, additional, Warady, Bradley A., additional, Webster, Angela C., additional, Weir, Matthew R., additional, Wish, Jay B., additional, and Wong, Muh Geot, additional

Published
2023
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26. Contributors

Author

Abudayyeh, Ala, primary, Adrogué, Horacio J., additional, Allon, Michael, additional, Arif-Tiwari, Hina, additional, Barratt, Jonathan, additional, Berns, Jeffrey S., additional, Bjornstad, Petter, additional, Bomback, Andrew S., additional, Bowling, C. Barrett, additional, Braun, Daniela A., additional, Brewster, Ursula C., additional, Carson, John M., additional, Cattran, Daniel C., additional, Chandran, Sindhu, additional, Chapman, Arlene B., additional, Cherney, David, additional, Coca, Steven G., additional, Cohen, Debbie L., additional, Crawford, Brendan D., additional, Curhan, Gary C., additional, Dad, Taimur, additional, D'Agati, Vivette D., additional, Derebail, Vimal K., additional, De Vriese, An S., additional, de Zeeuw, Dick, additional, DuBose, Thomas D., additional, Emmett, Michael, additional, Evenepoel, Pieter, additional, Fairhead, Todd, additional, Falk, Ronald J., additional, Fervenza, Fernando C., additional, Finkel, Kevin W., additional, Födinger, Manuela, additional, Gbadegesin, Rasheed A., additional, Gehr, Todd W.B., additional, Gilbert, Scott J., additional, Gill, Jagbir S., additional, Gonwa, Thomas A., additional, Greenberg, Arthur, additional, Gregory, Martin C., additional, Herlitz, Leal, additional, Hildebrandt, Friedhelm, additional, Hladik, Gerald A., additional, Hladunewich, Michelle A., additional, Hoenig, Melanie P., additional, Hogan, Jonathan, additional, House, Andrew A., additional, Hutchison, Alastair J., additional, Ikizler, T. Alp, additional, Inker, Lesley A., additional, Ison, Michael G., additional, James, Matthew T., additional, Jennette, J. Charles, additional, Kain, Renate, additional, Kala, Jaya, additional, Kalantar-Zadeh, Kamyar, additional, Kalb, Bobby, additional, Kopp, Jeffrey B., additional, Knoll, Greg, additional, Kulkarni, Dhananjay P., additional, Lan, James, additional, Levey, Andrew S., additional, Lewis, Ed, additional, Linas, Stuart L., additional, Luciano, Randy L., additional, Lytvyn, Yuliya, additional, Macedo, Etienne, additional, Madias, Nicolaos E., additional, Martin, Diego R., additional, Matzke, Gary R., additional, Mehrotra, Rajnish, additional, Mehta, Ankit N., additional, Mehta, Ravindra L., additional, Meyers, Catherine M., additional, Misra, Madhukar, additional, Moe, Sharon M., additional, Nachman, Patrick H., additional, Nicolle, Lindsay E., additional, Nolin, Thomas D., additional, O'Hare, Ann M., additional, Pannu, Neesh, additional, Peixoto, Aldo J., additional, Perazella, Mark A., additional, Prochaska, Megan, additional, Provenzano, Laura Ferreira, additional, Quarles, L. Darryl, additional, Radhakrishnan, Jai, additional, Reddy, Bharathi, additional, Rizk, Dana V., additional, Ronco, Claudio, additional, Rosenberg, Avi Z., additional, Rosenblum, Norman D., additional, Sampson, Matthew G., additional, Sanders, Paul W., additional, Sarnak, Mark J., additional, Scheinman, Steven J., additional, Schnaper, H. William, additional, Schrauben, Sarah, additional, Semelka, Richard C., additional, Shirali, Anushree C., additional, Sica, Domenic A., additional, Sunder-Plassmann, Gere, additional, Sutherland, Richard W., additional, Szerlip, Harold M., additional, Kurella Tamura, Manjula, additional, Tangren, Jessica Sheehan, additional, Thurman, Joshua M., additional, Tonelli, Marcello, additional, Townsend, Raymond R., additional, Trachtman, Howard, additional, Turner, Jeffrey M., additional, Vardhan, Anand, additional, Verbalis, Joseph G., additional, Vincenti, Flavio G., additional, Vivarelli, Marina, additional, Voora, Raven, additional, Wadei, Hani M., additional, Warady, Bradley A., additional, Weidemann, Darcy K., additional, Weiner, Daniel E., additional, Whittier, William L., additional, Wilcox, Christopher S., additional, Wish, Jay B., additional, and Yeo, See Cheng, additional

Published
2018
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31. Contributors

Author

Agarwal, Rajiv, primary, Aghemo, Alessio, additional, Al-Lawati, Ali, additional, Allon, Michael, additional, Andrews, Walter S., additional, Annunziato, Rachel A., additional, Araya, Carlos E., additional, Asif, Arif, additional, Ayoob, Rose M., additional, Baracco, Rossana, additional, Bargman, Joanne, additional, Beathard, Gerald A., additional, Bellasi, Antonio, additional, Bennett, William M., additional, Berns, Jeffrey S., additional, Bieber, Scott, additional, Block, Geoffrey A., additional, Boccardo, Paola, additional, Brookens, Andrew, additional, Brophy, Patrick D., additional, Brunelli, Steven, additional, Burkart, John M., additional, Bushinsky, David, additional, Campese, Vito M., additional, Cepeda, Celina Denise, additional, Chadha, Vimal, additional, Chan, Christopher T., additional, Chand, Deepa H., additional, Chang, Anthony, additional, Chang, Tara I., additional, Charytan, Chaim, additional, Chen, Joline L.T., additional, Chen, Wei, additional, Claudio, Ronco, additional, Collins, Allan J., additional, Crabtree, John H., additional, Crowley, Lisa E., additional, Cukor, Daniel, additional, Davies, Simon J., additional, Deger, Serpil Muge, additional, Depner, Thomas A., additional, Diaz-Buxo, Jose A., additional, Dinwiddie, Lesley C., additional, Dukkipati, Ramanath, additional, Duncan, Sarah E., additional, Fabrizi, Fabrizio, additional, Fischbach, Michel, additional, Fishbane, Steven, additional, Fissell, William Henry, additional, Foster, Bethany, additional, Galbusera, Miriam, additional, Gennari, F. John, additional, Ghannoum, Marc, additional, Ghazan-Shahi, Sassan, additional, Goldstein, Stuart L., additional, Gotch, Frank A., additional, Greenwood, Sharlene, additional, Haffner, Dieter, additional, Himmele, Rainer, additional, Holland, Janet E., additional, Holley, Jean L., additional, Holmes, Clifford, additional, Hooper, Stephen R., additional, Hothi, Daljit K., additional, Hou, Susan, additional, Hutchison, Alastair J., additional, Ikizler, T. Alp, additional, Jaber, Bertrand L., additional, Jassal, Sarbjit Vanita, additional, Kalantar-Zadeh, Kamyar, additional, Koh Jee Kam, Timothy, additional, Kaplan, Mark, additional, Kathuria, Pranay, additional, Kaufman, Jeffrey L., additional, Khanna, Ramesh, additional, Khosla, Neenoo, additional, Kimmel, Paul L., additional, Kooienga, Laura, additional, Koufaki, Pelagia, additional, Kovalik, Eugene C., additional, Kreuzer, Martin, additional, Krishna, Vinay Narasimha, additional, Krishnan, Mahesh, additional, Kuhlmann, Martin K., additional, Lakdawala, Ravi S., additional, Lam, Danica, additional, Lambie, Mark, additional, Lok, Charmaine E., additional, Mahan, John D., additional, Manley, Harold J., additional, Martin, Kevin J., additional, Martin, Paul, additional, Mathur, Piyush, additional, McIntyre, Christopher W., additional, Mehrotra, Rajnish, additional, Mehta, Ravindra L., additional, Mescia, Federica, additional, Mitsnefes, Mark M., additional, Modi, Gopesh K., additional, Moist, Louise, additional, Moodalbail, Divya G., additional, Moritz, Michael L., additional, Moss, Alvin H., additional, Nalesso, Federico, additional, Nessim, Sharon J., additional, Neul, Shari K., additional, Nissenson, Allen R., additional, Olyaei, Ali J., additional, Ortiz-Melo, David I., additional, Palmer, Biff F., additional, Palmer, Suetonia C., additional, Parfrey, Patrick S., additional, Pencille, Melissa, additional, Pham, Phuong-Chi T., additional, Pham, Phuong-Thu T., additional, Pittard, Joanne D., additional, Remuzzi, Giuseppe, additional, Rhee, Connie M., additional, Rigatto, Claudio, additional, Roberts, Darren M., additional, Rodriguez, Rudolph A., additional, Ronco, Claudio, additional, Rosenthal, Deborah, additional, Sadler, John H., additional, Satko, Scott G., additional, Schaefer, Franz, additional, Selewski, David T., additional, Sethna, Christine B., additional, Shah, Hitesh H., additional, Shapiro, Ron, additional, Sherman, Richard A., additional, Shroff, Rukshana, additional, Singer, Pamela, additional, Smith, Jodi M., additional, Somers, Michael J.G., additional, Soo, Euan, additional, Spinowitz, Bruce S., additional, Stein, Deborah, additional, Stivelman, John C., additional, Strippoli, Giovanni F.M., additional, Stronach, Lynsey, additional, Susantitaphong, Paweena, additional, Szeto, Cheuk-Chun, additional, Thomas, Rebecca, additional, Tolwani, Ashita, additional, Traum, Avram Z., additional, Vachharajani, Tushar, additional, Valentini, Rudolph P., additional, VanDeVoorde, René G., additional, Vardhan, Anand, additional, Vo, Thanh-Mai, additional, Wagner, Thor A., additional, Warady, Bradley A., additional, Wesseling-Perry, Katherine, additional, Westcott, Spencer, additional, Wetmore, James B., additional, Wille, Keith, additional, Williams, Mark E., additional, Wish, Jay B., additional, Yousaf, Farhanah, additional, Zaloszyc, Ariane, additional, and Zaritsky, Joshua, additional

Published
2017
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44. Contributors

Author

Adler, Sharon, primary, Adrogué, Horacio J., additional, Allon, Michael, additional, Arif-Tiwari, Hina, additional, Arroyo, Vincente, additional, Avery, Robin K., additional, Avila-Casado, Carmen, additional, Barratt, Jonathan, additional, Berns, Jeffrey S., additional, Bomback, Andrew S., additional, Bonventre, Joseph V., additional, Bowling, C. Barrett, additional, Brewster, Ursula C., additional, Briggs, Josephine P., additional, Cattran, Daniel C., additional, Chandran, Sindhu, additional, Chapman, Arlene B., additional, Coca, Steven G., additional, Conlon, Peter J., additional, Copelovitch, Lawrence A., additional, Curhan, Gary, additional, D’Agati, Vivette D., additional, Daoud, Jacques R., additional, de Zeeuw, Dick, additional, Dennen, Paula, additional, Derebail, Vimal K., additional, DuBose, Thomas D., additional, Emmett, Michael, additional, Fairhead, Todd, additional, Falk, Ronald J., additional, Feehally, John, additional, Fernández, Javier, additional, Fervenza, Fernando C., additional, Fioretto, Paola, additional, Födinger, Manuela, additional, Furth, Susan L., additional, Gehr, Todd W.B., additional, Gilbert, Scott J., additional, Gill, Jagbir S., additional, Gipson, Debbie S., additional, Goldstein-Fuchs, D. Jordi, additional, Greenberg, Arthur, additional, Gregory, Martin C., additional, Gunaratnam, Lakshman, additional, Hakim, Raymond M., additional, Hildebrandt, Friedhelm, additional, Hladunewich, Michelle A., additional, Hogan, Jonathan, additional, Hou, Susan, additional, House, Andrew A., additional, Huan, Yonghong, additional, Hutchison, Alastair J., additional, Inker, Lesley A., additional, James, Matthew T., additional, Jayne, David, additional, Jennette, J. Charles, additional, Jiménez, Wladimiro, additional, Kain, Renate, additional, Kalantar-Zadeh, Kamyar, additional, Kalb, Bobby, additional, Knoll, Greg, additional, Kriz, Wilhelm, additional, Tamura, Manjula Kurella, additional, LaPierre, Amy Frances, additional, Lambers Heerspink, Hiddo J., additional, Levey, Andrew S., additional, Lewis, Edmund J., additional, Linas, Stuart L., additional, Macedo, Etienne, additional, Madias, Nicolaos E., additional, Magee, Colm, additional, Mariani, Laura H., additional, Martin, Diego R., additional, Matzke, Gary R., additional, McQuillan, Rory F., additional, Mehrotra, Rajnish, additional, Mehta, Ankit N., additional, Mehta, Ravindra L., additional, Meyers, Catherine M., additional, Meyrier, Alain, additional, Moe, Sharon M., additional, Nast, Cynthia C., additional, Nicolle, Lindsay E., additional, Nolin, Thomas D., additional, O’Hare, Ann M., additional, O’Toole, John F., additional, Pannu, Neesh, additional, Perazella, Mark A., additional, Pusey, Charles D., additional, Quarles, L. Darryl, additional, Radhakrishnan, Jai, additional, Rastegar, Asghar, additional, Redahan, Lynn, additional, Rizk, Dana V., additional, Ronco, Claudio, additional, Rosenblum, Norman D., additional, Salama, Alan D., additional, Sanders, Paul W., additional, Sarnak, Mark J., additional, Scheinman, Steven J., additional, Schnermann, Jurgen B., additional, Semelka, Richard C., additional, Shirali, Anushree, additional, Sica, Domenic A., additional, Sunder-Plassmann, Gere, additional, Sutherland, Richard W., additional, Szerlip, Harold M., additional, Tonelli, Marcello, additional, Townsend, Raymond R., additional, Trachtman, Howard, additional, Turner, Jeffrey M., additional, Vardhan, Anand, additional, Vellanki, Kavitha, additional, Verbalis, Joseph G., additional, Vincenti, Flavio G., additional, Waikar, Sushrut S., additional, Weiner, Daniel E., additional, White, Colin T., additional, Whittier, William L., additional, Wilcox, Christopher S., additional, Wish, Jay B., additional, and Yiu, Vivian, additional

Published
2014
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49. Use of erythropoiesis-stimulating agents in patients with anemia of chronic kidney disease: overcoming the pharmacological and pharmacoeconomic limitations of existing therapies

Author

Wish, Jay B. and Coyne, Daniel W.

Subjects
Erythropoietin -- Dosage and administration, Anemia -- Drug therapy, Kidney diseases -- Complications and side effects
Abstract

Stage 3 chronic kidney disease (CKD), which is characterized by a glomerular filtration rate of 30 to 60 mL/min/1.73 [m.sup.2] (reference range, 90-200 mL/min/1.73[m.sup.2] for a 20-year-old, with a decrease [...]

Published
2007

50. Iron Administration, Infection, and Anemia Management in CKD: Untangling the Effects of Intravenous Iron Therapy on Immunity and Infection Risk

Author

DIGD-Medisch 1, Ganz, Tomas, Aronoff, George R., Gaillard, Carlo A.J.M., Goodnough, Lawrence T., Macdougall, Iain C., Mayer, Gert, Porto, Graça, Winkelmayer, Wolfgang C., Wish, Jay B., DIGD-Medisch 1, Ganz, Tomas, Aronoff, George R., Gaillard, Carlo A.J.M., Goodnough, Lawrence T., Macdougall, Iain C., Mayer, Gert, Porto, Graça, Winkelmayer, Wolfgang C., and Wish, Jay B.

Published
2020

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