1. Can CAPTURE be used to identify undiagnosed patients with mild-to-moderate COPD likely to benefit from treatment?
- Author
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Byron Thomashow, Barbara P. Yawn, Stephen I. Rennard, Catherine A. Meldrum, Barry J. Make, David M. Mannino, Karen G. Malley, MeiLan K. Han, Julia F. Houfek, Fernando J. Martinez, Elizabeth D. Bacci, Wilson Quezada, Nancy Kline Leidy, Randall W. Brown, and Wassim W. Labaki
- Subjects
Male ,Vital capacity ,medicine.medical_specialty ,Exacerbation ,Vital Capacity ,undiagnosed COPD ,peak expiratory flow ,Primary care ,International Journal of Chronic Obstructive Pulmonary Disease ,Airflow obstruction ,Sensitivity and Specificity ,case-finding ,Pulmonary Disease, Chronic Obstructive ,03 medical and health sciences ,FEV1/FVC ratio ,0302 clinical medicine ,Forced Expiratory Volume ,Surveys and Questionnaires ,Internal medicine ,screening tool ,medicine ,Humans ,COPD ,Prospective Studies ,030212 general & internal medicine ,Aged ,Original Research ,Aged, 80 and over ,business.industry ,Respiratory disease ,General Medicine ,Middle Aged ,medicine.disease ,respiratory tract diseases ,3. Good health ,Clinical trial ,Cross-Sectional Studies ,030228 respiratory system ,Case-Control Studies ,Disease Progression ,Female ,Symptom Assessment ,business - Abstract
Nancy K Leidy,1 Fernando J Martinez,2 Karen G Malley,1 David M Mannino,3 MeiLan K Han,4 Elizabeth D Bacci,5 Randall W Brown,6 Julia F Houfek,7 Wassim W Labaki,4 Barry J Make,8 Catherine A Meldrum,4 Wilson Quezada,9 Stephen Rennard,10 Byron Thomashow,9 Barbara P Yawn11 1Evidera, Patient-Centered Research, Bethesda, MD, USA; 2Weill Cornell Medicine, Joan & Sanford Weill Department of Medicine, New York, NY, USA; 3University of Kentucky, Preventive Medicine & Environmental Health, Lexington, KY, USA; 4University of Michigan, Division of Pulmonary & Critical Care Medicine, Ann Arbor, MI, USA; 5Evidera, Patient-Centered Research, Seattle, WA, USA; 6University of Michigan, Department of Health Behavior & Health Education, School of Public Health, Ann Arbor, MI, USA; 7University of Nebraska Medical Center College of Nursing, Omaha, NE, USA; 8National Jewish Health, Department of Medicine, Division of Pulmonary, Critical Care & Sleep Medicine, Denver, CO, USA; 9Columbia University Medical Center, Division of Pulmonary, Allergy, & Critical Care, New York, NY, USA; 10AstraZeneca, IMED Biotech Unit, Cambridge, UK & University of Nebraska Medical Center, Department of Medicine, Omaha, NE, USA; 11University of Minnesota, Department of Family & Community Health, Minneapolis, MN & COPD Foundation, Miami, FL, USA Background: COPD Assessment in Primary Care To Identify Undiagnosed Respiratory Disease and Exacerbation Risk (CAPTURE™) uses five questions and peak expiratory flow (PEF) thresholds (males ≤350 L/min; females ≤250 L/min) to identify patients with a forced expiratory volume in 1 second (FEV1)/forced vital capacity (FVC) 2: 37% vs 5%, p10: 86% vs 57%, p
- Published
- 2018