310 results on '"Wilson, Nicola K."'
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2. Adaptation to ex vivo culture reduces human hematopoietic stem cell activity independently of the cell cycle
3. Maintenance of hematopoietic stem cells by non-tyrosine-phosphorylated STAT5 and JAK inhibition
4. Preleukemic single-cell landscapes reveal mutation-specific mechanisms and gene programs predictive of AML patient outcomes
5. Genotoxic aldehyde stress prematurely ages hematopoietic stem cells in a p53-driven manner
6. STAT1 is essential for HSC function and maintains MHCIIhi stem cells that resist myeloablation and neoplastic expansion
7. Single-cell transcriptomics reveals the identity and regulators of human mast cell progenitors
8. p57Kip2 regulates embryonic blood stem cells by controlling sympathoadrenal progenitor expansion
9. Unique molecular and functional features of extramedullary hematopoietic stem and progenitor cell reservoirs in humans
10. Multi-omics analysis defines highly refractory RAS burdened immature subgroup of infant acute lymphoblastic leukemia
11. CHD7 and Runx1 interaction provides a braking mechanism for hematopoietic differentiation
12. Blood and immune development in human fetal bone marrow and Down syndrome
13. Single-cell multi-omics analysis of COVID-19 patients with pre-existing autoimmune diseases shows aberrant immune responses to infection
14. Simultaneous Analysis of Single-Cell Transcriptomes and Cell Surface Protein Expression of Human Hematopoietic Stem Cells and Progenitors Using the 10x Genomics Platform
15. Manipulating niche composition limits damage to haematopoietic stem cells during Plasmodium infection
16. Cohesin-dependent regulation of gene expression during differentiation is lost in cohesin-mutated myeloid malignancies
17. Single-cell chromatin accessibility maps reveal regulatory programs driving early mouse organogenesis
18. Single-Cell Analysis of Hematopoietic Stem Cells
19. Single‐cell multi‐omics analysis of COVID‐19 patients with pre‐existing autoimmune diseases shows aberrant immune responses to infection
20. Bespoke single cell molecular and tissue-scale analysis reveals mechanisms underpinning development and disease in complex developing cell populations
21. Single-cell approaches identify the molecular network driving malignant hematopoietic stem cell self-renewal
22. A single-cell hematopoietic landscape resolves 8 lineage trajectories and defects in Kit mutant mice
23. Interactions between lineage‐associated transcription factors govern haematopoietic progenitor states
24. Reconstructing blood stem cell regulatory network models from single-cell molecular profiles
25. Yolk sac cell atlas reveals multiorgan functions during human early development
26. Expression profiling of cerebrospinal fluid identifies dysregulated antiviral mechanisms in multiple sclerosis.
27. Single‐cell multi‐omics analysis of COVID‐19 patients with pre‐existing autoimmune diseases shows aberrant immune responses to infection.
28. Genotoxic aldehyde stress prematurely ages hematopoietic stem cells in a p53-driven manner
29. A single-cell resolution map of mouse hematopoietic stem and progenitor cell differentiation
30. Integrated genome-scale analysis of the transcriptional regulatory landscape in a blood stem/progenitor cell model
31. Introduction to a review series on single-cell genomics: getting ready for clinical impact in leukemia and myeloid neoplasms
32. 3159 – A SINGLE-CELL PROTEIN-TRANSCRIPTOME ATLAS OF HAEMATOPOIESIS ACROSS THE HUMAN LIFESPAN
33. Adaptation toex vivoculture drives human haematopoietic stem cell loss of repopulation capacity in a cell cycle independent manner
34. Resolving early mesoderm diversification through single-cell expression profiling
35. Single-cell multi-omics analysis of the immune response in COVID-19
36. Multi-organ functions of yolk sac during human early development
37. Endothelial-specific Gata3 expression is required for hematopoietic stem cell generation
38. Genome-wide analysis of transcriptional regulators in human HSPCs reveals a densely interconnected network of coding and noncoding genes
39. Coagulation factor V is a T-cell inhibitor expressed by leukocytes in COVID-19
40. Multi-omics analysis defines highly refractory RAS burdened immature subgroup of infant acute lymphoblastic leukemia
41. Unique molecular and functional features of extramedullary hematopoietic stem and progenitor cell reservoirs in humans
42. GFI1 and GFI1B control the loss of endothelial identity of hemogenic endothelium during hematopoietic commitment
43. Coagulation factor V is a T-cell inhibitor expressed by leukocytes in COVID-19
44. Two distinct auto-regulatory loops operate at the PU.1 locus in B cells and myeloid cells
45. Cell of Origin in AML: Susceptibility to MN1-Induced Transformation Is Regulated by the MEIS1/AbdB-like HOX Protein Complex
46. Gata2, Fli1, and Scl Form a Recursively Wired Gene-Regulatory Circuit during Early Hematopoietic Development
47. Myeloid-biased HSC require Semaphorin 4A from the bone marrow niche for self-renewal under stress and life-long persistence
48. 3166 – A PROTEIN‐TRANSCRIPTOME ATLAS OF HAEMATOPOIESIS ACROSS THE HUMAN LIFESPAN
49. Key regulators control distinct transcriptional programmes in blood progenitor and mast cells
50. Single-cell molecular profiling provides a high-resolution map of basophil and mast cell development
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