Search

Your search keyword '"Wilson, Elisabeth R."' showing total 14 results
Start Over Author "Wilson, Elisabeth R."
14 results on '"Wilson, Elisabeth R."'

1. KDM6B protects T-ALL cells from NOTCH1-induced oncogenic stress

Author

Issa, Nancy, Bjeije, Hassan, Wilson, Elisabeth R., Krishnan, Aishwarya, Dunuwille, Wangisa M. B., Parsons, Tyler M., Zhang, Christine R., Han, Wentao, Young, Andrew L., Ren, Zhizhong, Ge, Kai, Wang, Eunice S., Weng, Andrew P., Cashen, Amanda, Spencer, David H., and Challen, Grant A.

Published
2023
Full Text
View/download PDF

6. The impact of Down syndrome‐specific non‐malignant hematopoietic regeneration in the bone marrow on the detection of leukemic measurable residual disease

Author

Hsu, Fan‐Chi, primary, Hudson, Chad, additional, Wilson, Elisabeth R., additional, Pardo, Laura M., additional, Singleton, Timothy P., additional, Xu, Dongbin, additional, Zehentner, Barbara K., additional, Hitzler, Johann, additional, Berman, Jason, additional, Wells, Denise A., additional, Loken, Michael R., additional, and Brodersen, Lisa Eidenschink, additional

Published
2023
Full Text
View/download PDF

7. Focal disruption of DNA methylation dynamics at enhancers in IDH-mutant AML cells

Author

Wilson, Elisabeth R., primary, Helton, Nichole M., additional, Heath, Sharon E., additional, Fulton, Robert S., additional, Payton, Jacqueline E., additional, Welch, John S., additional, Walter, Matthew J., additional, Westervelt, Peter, additional, DiPersio, John F., additional, Link, Daniel C., additional, Miller, Christopher A., additional, Ley, Timothy J., additional, and Spencer, David H., additional

Published
2021
Full Text
View/download PDF

8. Genome-wide analysis of focal DNA hypermethylation in IDH-mutant AML samples

Author

Wilson, Elisabeth R., primary, Helton, Nichole M., additional, Heath, Sharon E., additional, Fulton, Robert S., additional, Payton, Jacqueline E., additional, Welch, John S., additional, Walter, Matthew J., additional, Westervelt, Peter, additional, DiPersio, John F., additional, Link, Daniel C., additional, Miller, Christopher A., additional, Ley, Timothy J., additional, and Spencer, David H., additional

Published
2021
Full Text
View/download PDF

10. Deciphering the Significance of CD56 Expression in Pediatric Acute Myeloid Leukemia: A Report from the Children's Oncology Group

Author

Pardo, Laura M., primary, Voigt, Andrew P., additional, Alonzo, Todd A., additional, Wilson, Elisabeth R., additional, Gerbing, Robert B., additional, Paine, Dana J., additional, Dai, Fangyan, additional, Menssen, Andrew J., additional, Raimondi, Susana C., additional, Hirsch, Betsy A., additional, Gamis, Alan S., additional, Meshinchi, Soheil, additional, Wells, Denise A., additional, Brodersen, Lisa Eidenschink, additional, and Loken, Michael R., additional

Published
2019
Full Text
View/download PDF

11. Phenotype in combination with genotype improves outcome prediction in acute myeloid leukemia: a report from Children’s Oncology Group protocol AAML0531

Author

Voigt, Andrew P., primary, Brodersen, Lisa Eidenschink, additional, Alonzo, Todd A., additional, Gerbing, Robert B., additional, Menssen, Andrew J., additional, Wilson, Elisabeth R., additional, Kahwash, Samir, additional, Raimondi, Susana C., additional, Hirsch, Betsy A., additional, Gamis, Alan S., additional, Meshinchi, Soheil, additional, Wells, Denise A., additional, and Loken, Michael R., additional

Published
2017
Full Text
View/download PDF

12. Contribution of CTCF binding to transcriptional activity at the HOXAlocus in NPM1-mutant AML cells

Author

Ghasemi, Reza, Struthers, Heidi, Wilson, Elisabeth R., and Spencer, David H.

Abstract

Transcriptional regulation of the HOXAgenes is thought to involve CTCF-mediated chromatin loops and the opposing actions of the COMPASS and Polycomb epigenetic complexes. We investigated the role of these mechanisms at the HOXAcluster in AML cells with the common NPM1c mutation, which express both HOXAand HOXBgenes. CTCF binding at the HOXAlocus is conserved across primary AML samples, regardless of HOXAgene expression, and defines a continuous chromatin domain marked by COMPASS-associated histone H3 trimethylation in NPM1-mutant primary AML samples. Profiling of the three-dimensional chromatin architecture in primary AML samples with the NPM1c mutation identified chromatin loops between the HOXAcluster and loci in the SNX10and SKAP2genes, and an intergenic region located 1.4?Mbp upstream of the HOXAlocus. Deletion of CTCF binding sites in the NPM1-mutant OCI-AML3 AML cell line reduced multiple long-range interactions, but resulted in CTCF-independent loops with sequences in SKAP2that were marked by enhancer-associated histone modifications in primary AML samples. HOXAgene expression was maintained in CTCF binding site mutants, indicating that transcriptional activity at the HOXAlocus in NPM1-mutant AML cells may be sustained through persistent interactions with SKAP2enhancers, or by intrinsic factors within the HOXAgene cluster.

Published
2021
Full Text
View/download PDF

14. Down Syndrome AML Is Unique in Phenotype Both at Diagnosis and in Post Chemotherapy Regeneration

Author

Wilson, Elisabeth R, primary, Brodersen, Lisa Eidenschink, additional, Zehentner, Barbara Katharina, additional, Menssen, Andrew J., additional, Voigt, Andrew P., additional, Pardo, Laura, additional, Wells, Denise A., additional, Hitzler, Johann, additional, Berman, Jason N., additional, Alonzo, Todd A., additional, Kahwash, Samir B., additional, Meshinchi, Soheil, additional, and Loken, Michael R., additional

Published
2016
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results