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26 results on '"Willigenburg, Thomas"'

1. Magnetic Resonance-Guided Adaptive Radiation Therapy for Prostate Cancer: The First Results from the MOMENTUM study—An International Registry for the Evidence-Based Introduction of Magnetic Resonance-Guided Adaptive Radiation Therapy

Author

Teunissen, Frederik R., Willigenburg, Thomas, Tree, Alison C., Hall, William A., Choi, Seungtaek L., Choudhury, Ananya, Christodouleas, John P., de Boer, Johannes C.J., de Groot-van Breugel, Eline N., Kerkmeijer, Linda G.W., Pos, Floris J., Schytte, Tine, Vesprini, Danny, Verkooijen, Helena M., and van der Voort van Zyp, Jochem R.N.

Published
2023
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13. Magnetic Resonance-Guided Adaptive Radiation therapy for Prostate Cancer: The First Results from the MOMENTUM study-An International Registry for the Evidence-Based Introduction of Magnetic Resonance-Guided Adaptive Radiation Therapy

Author

Cancer, Onderzoek Radiotherapie, Arts-assistenten Radiotherapie, MS Radiotherapie, Trialbureau Beeld, Teunissen, Frederik R, Willigenburg, Thomas, Tree, Alison C, Hall, William A, Choi, Seungtaek L, Choudhury, Ananya, Christodouleas, John P, de Boer, Johannes C J, Groot-van Breugel, Eline N de, Kerkmeijer, Linda G W, Pos, Floris J, Schytte, Tine, Vesprini, Danny, Verkooijen, Helena M, Voort van Zyp, Jochem R N van der, Cancer, Onderzoek Radiotherapie, Arts-assistenten Radiotherapie, MS Radiotherapie, Trialbureau Beeld, Teunissen, Frederik R, Willigenburg, Thomas, Tree, Alison C, Hall, William A, Choi, Seungtaek L, Choudhury, Ananya, Christodouleas, John P, de Boer, Johannes C J, Groot-van Breugel, Eline N de, Kerkmeijer, Linda G W, Pos, Floris J, Schytte, Tine, Vesprini, Danny, Verkooijen, Helena M, and Voort van Zyp, Jochem R N van der

Published
2023

14. MRI-guided stereotactic radiotherapy for localised prostate cancer

Author

Willigenburg, Thomas, Lagendijk, J.J.W., Voort van Zyp, J.R.N. van der, Boer, J.C.J. de, and University Utrecht

Subjects
MRI-guided radiotherapy, Prostate cancer, MR-Linac, Stereotactic radiotherapy, Extremely hypofractionated radiotherapy, Stereotactic body radiation therapy, recurrent prostate cancer, clinical outcomes
Abstract

Although the incidence of prostate cancer is high, improvements in treatments have led to high survival rates in patients with low- and intermediate-risk prostate cancer. Therefore, it is even more important that treatments for these patients are minimally invasive and cause as little side effects as possible. The last decades, radiotherapy treatments have changed significantly. One of the clinically introduced innovations is the MR-Linac, a combination of a linear accelerator and an MRI scanner. This machine allows high-quality imaging before and during treatment and daily treatment plan optimisation based on the changing anatomy. This enables more precise radiotherapy and therefore better sparing of healthy organs, which will potentially lead to less side effects such as urinary complaints and erectile dysfunction. This thesis provides insight into the clinical introduction and first period of prostate cancer treatment on the MR-Linac. In part 1 of this thesis, new workflows and technological developments for MRI-guided prostate cancer treatment are presented, which are aimed at enabling extremely hypofractionated radiotherapy for prostate cancer in one or two treatment fractions. With these new workflows, the irradiated volumes can be reduced significantly. Furthermore, early (patient-reported) outcomes of MRI-guided prostate cancer radiotherapy are investigated within two cohort studies, including the international MOMENTUM study. These clinical results are already promising. Part 2 of this thesis focusses on re-irradiation in patients with recurrent prostate cancer after primary radiotherapy treatment. We present research on the feasibility of so-called single-fraction ‘focal salvage’ radiotherapy using external beam radiotherapy on the MR-Linac. The work presented in this thesis is part of the first steps towards MRI-guided, extremely high-precision radiotherapy treatment for (recurrent) prostate cancer in only one or two treatment sessions.

Published
2023

15. Magnetic Resonance-Guided Adaptive Radiation Therapy for Prostate Cancer: The First Results from the MOMENTUM study—An International Registry for the Evidence-Based Introduction of Magnetic Resonance-Guided Adaptive Radiation Therapy

Author

Teunissen, Frederik R., primary, Willigenburg, Thomas, additional, Tree, Alison C., additional, Hall, William A., additional, Choi, Seungtaek L., additional, Choudhury, Ananya, additional, Christodouleas, John P., additional, de Boer, Johannes C.J., additional, de Groot-van Breugel, Eline N., additional, Kerkmeijer, Linda G.W., additional, Pos, Floris J., additional, Schytte, Tine, additional, Vesprini, Danny, additional, Verkooijen, Helena M., additional, and van der Voort van Zyp, Jochem R.N., additional

Published
2022
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16. Clinical application of a sub-fractionation workflow for intrafraction re-planning during prostate radiotherapy treatment on a 1.5 Tesla MR-Linac: A practical method to mitigate intrafraction motion

Author

Arts-assistenten Radiotherapie, Cancer, Klinische Fysica RT, Fysica Radiotherapie Research, MS Radiotherapie, Experimentele klinische fysica, Willigenburg, Thomas, Zachiu, Cornel, Bol, Gijsbert H, de Groot-van Beugel, Eline N, Lagendijk, Jan J W, van der Voort van Zyp, Jochem R N, Raaymakers, Bas W, de Boer, Johannes C J, Arts-assistenten Radiotherapie, Cancer, Klinische Fysica RT, Fysica Radiotherapie Research, MS Radiotherapie, Experimentele klinische fysica, Willigenburg, Thomas, Zachiu, Cornel, Bol, Gijsbert H, de Groot-van Beugel, Eline N, Lagendijk, Jan J W, van der Voort van Zyp, Jochem R N, Raaymakers, Bas W, and de Boer, Johannes C J

Published
2022

17. Accumulated bladder wall dose is correlated with patient-reported acute urinary toxicity in prostate cancer patients treated with stereotactic, daily adaptive MR-guided radiotherapy

Author

Onderzoek Radiotherapie, Cancer, Arts-assistenten Radiotherapie, Klinische Fysica RT, Fysica Radiotherapie Research, Experimentele klinische fysica, MS Radiotherapie, Willigenburg, Thomas, van der Velden, Joanne M., Zachiu, Cornel, Teunissen, Frederik R., Lagendijk, Jan J.W., Raaymakers, Bas W., de Boer, Johannes C.J., van der Voort van Zyp, Jochem R.N., Onderzoek Radiotherapie, Cancer, Arts-assistenten Radiotherapie, Klinische Fysica RT, Fysica Radiotherapie Research, Experimentele klinische fysica, MS Radiotherapie, Willigenburg, Thomas, van der Velden, Joanne M., Zachiu, Cornel, Teunissen, Frederik R., Lagendijk, Jan J.W., Raaymakers, Bas W., de Boer, Johannes C.J., and van der Voort van Zyp, Jochem R.N.

Published
2022

18. The first patient-reported outcomes from the Utrecht Prostate Cohort (UPC): the first platform facilitating 'trials within cohorts' (TwiCs) for the evaluation of interventions for prostate cancer

Author

Cancer, Onderzoek Radiotherapie, MS Urologische Oncologie, Trialbureau Beeld, MS Radiotherapie, Teunissen, Frederik R, Willigenburg, Thomas, Meijer, Richard P, van Melick, Harm H E, Verkooijen, Helena M, van der Voort van Zyp, Jochem R N, Cancer, Onderzoek Radiotherapie, MS Urologische Oncologie, Trialbureau Beeld, MS Radiotherapie, Teunissen, Frederik R, Willigenburg, Thomas, Meijer, Richard P, van Melick, Harm H E, Verkooijen, Helena M, and van der Voort van Zyp, Jochem R N

Published
2022

19. Fast and accurate deformable contour propagation for intra-fraction adaptive magnetic resonance-guided prostate radiotherapy

Author

Onderzoek Radiotherapie, Cancer, Klinische Fysica RT, Fysica Radiotherapie Research, MS Radiotherapie, Experimentele klinische fysica, Willigenburg, Thomas, Zachiu, Cornel, Lagendijk, Jan J W, van der Voort van Zyp, Jochem R N, de Boer, Hans C J, Raaymakers, Bas W, Onderzoek Radiotherapie, Cancer, Klinische Fysica RT, Fysica Radiotherapie Research, MS Radiotherapie, Experimentele klinische fysica, Willigenburg, Thomas, Zachiu, Cornel, Lagendijk, Jan J W, van der Voort van Zyp, Jochem R N, de Boer, Hans C J, and Raaymakers, Bas W

Published
2022

20. Comparison of Library of Plans with two daily adaptive strategies for whole bladder radiotherapy

Author

Radiotherapie, Klinische Fysica RT, Cancer, MS Radiotherapie, Arts-assistenten Radiotherapie, Onderzoek Radiotherapie, den Boer, Duncan, den Hartogh, Mariska D., Kotte, Alexis N.T.J., van der Voort van Zyp, Jochem R.N., Noteboom, Juus L., Bol, Gijsbert H., Willigenburg, Thomas, Werensteijn-Honingh, Anita M., Jürgenliemk-Schulz, Ina M., van Lier, Astrid L.H.M.W., Kroon, Petra S., Radiotherapie, Klinische Fysica RT, Cancer, MS Radiotherapie, Arts-assistenten Radiotherapie, Onderzoek Radiotherapie, den Boer, Duncan, den Hartogh, Mariska D., Kotte, Alexis N.T.J., van der Voort van Zyp, Jochem R.N., Noteboom, Juus L., Bol, Gijsbert H., Willigenburg, Thomas, Werensteijn-Honingh, Anita M., Jürgenliemk-Schulz, Ina M., van Lier, Astrid L.H.M.W., and Kroon, Petra S.

Published
2021

21. Adaptive magnetic resonance-guided neurovascular-sparing radiotherapy for preservation of erectile function in prostate cancer patients

Author

Cancer, Onderzoek Radiotherapie, Urologie Onderzoek, Trialbureau Beeld, MS Radiotherapie, Teunissen, Frederik R, Wortel, Ruud C, Hes, Jochem, Willigenburg, Thomas, de Groot-van Breugel, Eline N, de Boer, Johannes C J, van Melick, Harm H E, Verkooijen, Helena M, van der Voort van Zyp, Jochem R N, Cancer, Onderzoek Radiotherapie, Urologie Onderzoek, Trialbureau Beeld, MS Radiotherapie, Teunissen, Frederik R, Wortel, Ruud C, Hes, Jochem, Willigenburg, Thomas, de Groot-van Breugel, Eline N, de Boer, Johannes C J, van Melick, Harm H E, Verkooijen, Helena M, and van der Voort van Zyp, Jochem R N

Published
2021

22. Development and internal validation of multivariable prediction models for biochemical failure after MRI-guided focal salvage high-dose-rate brachytherapy for radiorecurrent prostate cancer

Author

Onderzoek Radiotherapie, Cancer, MS Radiotherapie, Klinische Fysica RT, Fysica Radiotherapie Research, Arts-assistenten Radiotherapie, Willigenburg, Thomas, van Son, Marieke J, van de Pol, Sandrine M G, Eppinga, Wietse S C, Lagendijk, Jan J W, de Boer, Hans C J, Moerland, Marinus A, van der Voort van Zyp, Jochem R N, Peters, Max, Onderzoek Radiotherapie, Cancer, MS Radiotherapie, Klinische Fysica RT, Fysica Radiotherapie Research, Arts-assistenten Radiotherapie, Willigenburg, Thomas, van Son, Marieke J, van de Pol, Sandrine M G, Eppinga, Wietse S C, Lagendijk, Jan J W, de Boer, Hans C J, Moerland, Marinus A, van der Voort van Zyp, Jochem R N, and Peters, Max

Published
2021

23. Evaluation of daily online contour adaptation by radiation therapists for prostate cancer treatment on an MRI-guided linear accelerator

Author

Onderzoek Radiotherapie, Cancer, Fysica Radiotherapie Research, Arts-assistenten Radiotherapie, MS Radiotherapie, Klinische Fysica RT, Willigenburg, Thomas, de Muinck Keizer, Daan M, Peters, Max, Claes, An, Lagendijk, Jan J W, de Boer, Hans C J, van der Voort van Zyp, Jochem R N, Onderzoek Radiotherapie, Cancer, Fysica Radiotherapie Research, Arts-assistenten Radiotherapie, MS Radiotherapie, Klinische Fysica RT, Willigenburg, Thomas, de Muinck Keizer, Daan M, Peters, Max, Claes, An, Lagendijk, Jan J W, de Boer, Hans C J, and van der Voort van Zyp, Jochem R N

Published
2021

24. Focal salvage treatment for radiorecurrent prostate cancer: A magnetic resonance-guided stereotactic body radiotherapy versus high-dose-rate brachytherapy planning study

Author

Onderzoek Radiotherapie, Cancer, Experimentele klinische fysica, Fysica Radiotherapie Research, Klinische Fysica RT, MS Radiotherapie, Willigenburg, Thomas, Beld, Ellis, Hes, Jochem, Lagendijk, Jan J.W., de Boer, Hans C.J., Moerland, Marinus A., van der Voort van Zyp, Jochem R.N., Onderzoek Radiotherapie, Cancer, Experimentele klinische fysica, Fysica Radiotherapie Research, Klinische Fysica RT, MS Radiotherapie, Willigenburg, Thomas, Beld, Ellis, Hes, Jochem, Lagendijk, Jan J.W., de Boer, Hans C.J., Moerland, Marinus A., and van der Voort van Zyp, Jochem R.N.

Published
2020

25. Anatomically-adaptive multi-modal image registration for image-guided external-beam radiotherapy

Author

Experimentele klinische fysica, Cancer, Researchgr. Beeldg. Moleculaire Interv., Onderzoek Radiotherapie, MS Radiotherapie, Klinische Fysica RT, Zachiu, Cornel, Denis de Senneville, Baudouin, Willigenburg, Thomas, van der Voort van Zyp, Jochem R N, de Boer, J C J, Raaymakers, Bas W, Ries, Mario G, Experimentele klinische fysica, Cancer, Researchgr. Beeldg. Moleculaire Interv., Onderzoek Radiotherapie, MS Radiotherapie, Klinische Fysica RT, Zachiu, Cornel, Denis de Senneville, Baudouin, Willigenburg, Thomas, van der Voort van Zyp, Jochem R N, de Boer, J C J, Raaymakers, Bas W, and Ries, Mario G

Published
2020

26. Delivered dose quantification in prostate radiotherapy using online 3D cine imaging and treatment log files on a combined 1.5T magnetic resonance imaging and linear accelerator system

Author

Klinische Fysica RT, Kwaliteit Radiotherapie, Fysica Radiotherapie Research, Cancer, MS Radiotherapie, Onderzoek Radiotherapie, Experimentele klinische fysica, Kontaxis, Charis, de Muinck Keizer, Daan M., Kerkmeijer, Linda G.W., Willigenburg, Thomas, den Hartogh, Mariska D., van der Voort van Zyp, Jochem R.N., de Groot-van Breugel, Eline N., Hes, Jochem, Raaymakers, Bas W., Lagendijk, Jan J.W., de Boer, Hans C.J., Klinische Fysica RT, Kwaliteit Radiotherapie, Fysica Radiotherapie Research, Cancer, MS Radiotherapie, Onderzoek Radiotherapie, Experimentele klinische fysica, Kontaxis, Charis, de Muinck Keizer, Daan M., Kerkmeijer, Linda G.W., Willigenburg, Thomas, den Hartogh, Mariska D., van der Voort van Zyp, Jochem R.N., de Groot-van Breugel, Eline N., Hes, Jochem, Raaymakers, Bas W., Lagendijk, Jan J.W., and de Boer, Hans C.J.

Published
2020

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