166 results on '"Williams NN"'
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2. Short simulation training improves objective skills in established advanced practitioners managing emergencies on the ward and surgical intensive care unit.
- Author
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Pascual JL, Holena DN, Vella MA, Palmieri J, Sicoutris C, Selvan B, Fox AD, Sarani B, Sims C, Williams NN, and Schwab CW
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- 2011
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3. Endoscopic removal of eroded bands in vertical banded gastroplasty: a novel use of endoscopic scissors (with video)
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Evans JA, Williams NN, Chan EP, and Kochman ML
- Abstract
BACKGROUND: Vertical banded gastroplasty (VBG) as a surgical therapy for morbid obesity was first described in 1982. VBG involves partitioning the stomach with a vertical staple line and restricting the outlet pouch with a Gortex band. Complications of VBG include partial and total erosion of the band through the vertical staple line or through the lesser curvature into the gastric pouch. Band erosion occurs after surgery in 1% to 3% of patients, and patients may present with symptoms of obstruction, weight gain, nausea, pain, and bleeding. Unless a band has freely eroded from the stomach wall, allowing spontaneous elimination or simple endoscopic retrieval, surgical removal has been required heretofore. Previous attempts at endoscopic removal of eroded bands have included the use of neodymium-yttrium aluminum garnet laser ablation and other electrosurgical devices. Endoscopic scissors transection to remove an eroded laparoscopic band has been described in Europe but has not been performed in the United States. OBJECTIVE: In this series, we describe the endoscopic removal of partially eroded bands embedded in the gastric wall by using flexible endoscopic scissors to sever and subsequently withdraw the bands endoscopically through the mouth. CONCLUSIONS: Eroded gastric bands have been safely removed endoscopically in 2 ambulatory outpatients. DESIGN: Case series. SETTING: Tertiary-care academic center. MAIN OUTCOME MEASUREMENTS: Efficacy and safety. LIMITATIONS: Highly selected motivated patient population. [ABSTRACT FROM AUTHOR]
- Published
- 2006
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4. Comparison of Gastrostomy Techniques in Stroke Patients With Dysphagia: An Entropy-Balanced Analysis.
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Rouhi AD, Leon S, Roberson JL, Shreve LA, Nadolski GJ, Williams NN, and Dumon KR
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Introduction: Enteral nutrition is commonly placed via percutaneous endoscopic gastrostomy (PEG) or radiologically inserted gastrostomy (RIG) techniques. This study compared perioperative outcomes of PEG and RIG in adults with dysphagia caused by cerebral infarction., Methods: Adult stroke patients who underwent either PEG or RIG between 2018 and 2020 at a tertiary care center were reviewed retrospectively. Differences in baseline characteristics between PEG and RIG patients were adjusted using entropy-balanced weights. Multivariable weighted logistic and linear regressions were subsequently developed to evaluate the independent association between RIG and outcomes of interest., Results: 217 stroke patients met inclusion criteria, of whom 37 (17.0%) received PEG and 180 (83.0%) received RIG. Compared to PEG, patients with RIG were more commonly Medicare beneficiaries and had a higher burden of comorbidities as measured by the Charlson comorbidity index. Time to achieve goal feeds was comparable between PEG and RIG (3 d [interquartile range 2-5] vs 4 d [interquartile range 3-5], respectively, P = 0.059). After multivariate adjustment, RIG was associated with significantly lower odds of reoperation (adjusted odds ratio [AOR] 0.10, 95% CI 0.02-0.50, P = 0.005), cerebrovascular accident (AOR 0.24, 95% CI 0.00-0.74, P = 0.030), and intensive care unit admission (AOR 0.14, 95% CI 0.03-0.70, P = 0.017). Risk factors for in-hospital mortality among RIG included arrhythmia (AOR 6.54, 95% CI 1.67-15.48, P = 0.009), myocardial infarction (AOR 4.78, 95% CI 2.25-10.23, P = 0.009), and obesity (AOR 4.48, 95% CI 1.03-9.61, P = 0.047)., Conclusions: While both techniques are effective methods of enteral feeding in stroke patients, RIG may confer lower perioperative morbidity. Local referral patterns and individual patient comorbidities could influence outcomes following PEG or RIG, necessitating careful patient selection., (Copyright © 2024 Elsevier Inc. All rights reserved.)
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- 2024
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5. Safety of elective enteral access in elderly patients: a comparative analysis of perioperative risk.
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Leon S, Rouhi AD, Roberson JL, Shreve LA, Nadolski GJ, Williams NN, and Dumon KR
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- Humans, Aged, Male, Female, Retrospective Studies, Middle Aged, Adult, Age Factors, Gastrostomy adverse effects, Gastrostomy methods, Gastrostomy statistics & numerical data, Length of Stay statistics & numerical data, Hospital Mortality, Risk Factors, Aged, 80 and over, Risk Assessment methods, Patient Readmission statistics & numerical data, Reoperation statistics & numerical data, Enteral Nutrition methods, Enteral Nutrition adverse effects, Enteral Nutrition statistics & numerical data, Elective Surgical Procedures adverse effects
- Abstract
Background: Elderly patients can experience torpid hospitalization that is often characterized by malnutrition. In this setting, enteral feeding may facilitate improvement in nutritional status. This study aimed to compare the perioperative outcomes between elderly (age of ≥65 years old) and nonelderly (age of <65 years old) patients undergoing elective enteral access placement., Methods: Adult patients who underwent enteral access procedures between 2018 and 2020 at a tertiary care facility were retrospectively reviewed. Differences in baseline characteristics between nonelderly and elderly patients were adjusted using entropy-balanced weights. Subsequently, multivariate logistic and linear regression models were developed to evaluate the association between elderly status and outcomes of interest., Results: Overall, 914 patients with enteral access met the inclusion criteria, of whom 471 (51.5%) were elderly. Elderly patients more commonly received percutaneous gastrostomy and had a higher burden of comorbidities as measured using the Charlson Comorbidity Index than nonelderly patients. Multivariate risk adjustment generated a strongly balanced distribution of baseline covariates between patient groups. After adjustment, despite no significant association with inhospital mortality, reoperation, or time to feeding goals, elderly status was linked to an approximately 8-day reduction in length of stay (95% CI, -14.28 to -2.30; P = .007) and significantly lower odds of total parenteral nutrition (adjusted odds ratio [AOR], 0.59; 95% CI, 0.37-0.94; P = .026) and nonelective readmission (AOR, 0.65; 95% CI, 0.49-0.86; P = .003). In addition, elderly status was associated with significantly greater odds of nonhome discharge (AOR, 1.58; 95% CI, 1.17-2.13; P = .003)., Conclusion: Despite having more comorbidities than their nonelderly counterparts, elderly patients experienced favorable nutritional and perioperative outcomes after enteral access placement., (Copyright © 2024 Society for Surgery of the Alimentary Tract. Published by Elsevier Inc. All rights reserved.)
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- 2024
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6. Bariatric surgery in patients with preoperative therapeutic anticoagulation: a 2015-2021 MBSAQIP database study.
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Leon S, Rouhi AD, Perez JE, Alberstadt AN, Tewksbury CM, Gershuni VM, Altieri MS, Williams NN, and Dumon KR
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Background: The link between obesity and adverse cardiovascular events is well-established. With the rising prevalence of metabolic and bariatric surgery (MBS), a greater number of patients undergoing sleeve gastrectomy (SG) or Roux-en-Y gastric bypass (RYGB) may present with preoperative therapeutic anticoagulation (AC)., Objectives: This study evaluated perioperative outcomes of SG and RYGB in patients on preoperative AC., Setting: Patients reported to the 2015-2021 Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program (MBSAQIP) database., Methods: Adults undergoing primary SG or RYGB with and without preoperative anticoagulation (SG-AC or RYGB-AC and non-SG-AC or non-RYGB-AC, respectively) were analyzed from the 2015-2021 MBSAQIP database. Differences in baseline characteristics by AC status for each MBS were adjusted using entropy-balanced weights. Multivariable logistic and linear regressions were developed to analyze the independent association between AC and outcomes of interest., Results: Of 1,178,090 patients included, 72.0% (n = 850,682) had SG and 28.0% (n = 327,408) had RYGB, of which 1.8% (n = 15,021) and 1.9% (n = 6201) had AC, respectively. Compared to non-SG-AC and non-RYGB-AC, both SG-AC and RYGB-AC encountered higher absolute 30-day rates of anastomotic leak, deep vein thrombosis and gastrointestinal bleeding. Following multivariable adjustment, SG-AC was associated with significantly greater odds of adverse cardiovascular events, anastomotic leak, gastrointestinal bleeding, and greater operative length and length of stay. RYGB-AC was associated with higher odds of readmission, unplanned ICU admission, and ED visit., Conclusions: While preoperative AC may confer distinct outcomes between SG and RYGB, this 7-year study of MBSAQIP demonstrated an overall association with greater postoperative morbidity. Management of MBS patients with preoperative AC requires consideration of thrombohemorrhagic risks., (Copyright © 2024 American Society for Metabolic and Bariatric Surgery. Published by Elsevier Inc. All rights reserved.)
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- 2024
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7. Predicting Recurrent Deficiency and Suboptimal Monitoring of Thiamin Deficiency in Patients with Metabolic and Bariatric Surgery.
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Parrott JM, Parrott AJ, Parrott JS, Williams NN, and Dumon KR
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- Humans, Female, Male, Middle Aged, Adult, Machine Learning, Thiamine blood, Risk Factors, Postoperative Complications etiology, Postoperative Complications blood, Bariatric Surgery adverse effects, Thiamine Deficiency etiology, Thiamine Deficiency diagnosis, Recurrence
- Abstract
Introduction: Vitamin B1 (thiamine) deficiency (TD) after metabolic and bariatric surgery (MBS) is often insidious and, if unrecognized, can lead to irreversible damage or death. As TD symptoms are vague and overlap with other disorders, we aim to identify predictors of recurrent TD and failure to collect B1 labs., Methods: We analyzed a large sample of data from patients with MBS ( n = 878) to identify potential predictors of TD risk. We modeled recurrent TD and failure to collect B1 labs using classical statistical and machine learning (ML) techniques., Results: We identified clusters of labs associated with increased risk of recurrent TD: micronutrient deficiencies, abnormal blood indices, malnutrition, and fluctuating electrolyte levels (aIRR range: 1.62-4.68). Additionally, demographic variables associated with lower socioeconomic status were predictive of recurrent TD. ML models predicting characteristics associated with failure to collect B1 labs achieved 75-81% accuracy, indicating that clinicians may fail to match symptoms with the underlying condition., Conclusions: Our analysis suggests that both clinical and social factors can increase the risk of life-threatening TD episodes in some MBS patients. Identifying these indicators can help with diagnosis and treatment.
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- 2024
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8. Enteral Access Outcomes in Patients Hospitalized With Cardiac Disease: A Retrospective Cohort Study.
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Rouhi AD, Roberson JL, Alberstadt AN, Shah SK, Maurer M, Bader E, Williams NN, and Dumon KR
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- Humans, Retrospective Studies, Male, Female, Aged, Middle Aged, Length of Stay statistics & numerical data, Patient Readmission statistics & numerical data, Hospital Mortality, Nutritional Status, Aged, 80 and over, Gastrostomy statistics & numerical data, Malnutrition diagnosis, Malnutrition therapy, Malnutrition epidemiology, Malnutrition etiology, Hospitalization statistics & numerical data, Postoperative Complications epidemiology, Postoperative Complications etiology, Enteral Nutrition statistics & numerical data, Heart Diseases mortality, Heart Diseases therapy
- Abstract
Introduction: Patients admitted with principal cardiac diagnosis (PCD) can encounter difficult inpatient stays that are often marked by malnutrition. In this setting, enteral feeding may improve nutritional status. This study examined the association of PCD with perioperative outcomes after elective enteral access procedures., Methods: Adult patients who underwent enteral access procedures between 2018 and 2020 at a tertiary care institution were reviewed retrospectively. Differences in baseline characteristics between patients with and without PCD were adjusted using entropy balancing. Multivariable logistic and linear regressions were subsequently developed to evaluate the association between PCD and nutritional outcomes, perioperative morbidity and mortality, length of stay, and nonelective readmission after enteral access., Results: 912 patients with enteral access met inclusion criteria, of whom 84 (9.2%) had a diagnosis code indicating PCD. Compared to non-PCD, patients with PCD more commonly received percutaneous endoscopic gastrostomy by general surgery and had a higher burden of comorbidities as measured by the Charlson comorbidity index. Multivariable risk adjustment generated a strongly balanced distribution of baseline covariates between patient groups (standardized differences ranged from -2.45 × 10
-8 to 3.18 × 108 ). After adjustment, despite no significant association with in-hospital mortality, percentage change prealbumin, length of stay, or readmission, PCD was associated with an approximately 2.25-day reduction in time to meet goal feeds (95% CI -3.76 to -0.74, P = 0.004) as well as decreased odds of reoperation (adjusted odds ratio 0.28, 95% CI 0.09-0.86, P = 0.026) and acute kidney injury (adjusted odds ratio 0.24, 95% CI 0.06-0.91, P = 0.035)., Conclusions: Despite having more comorbidities than non-PCD, adult enteral access patients with PCD experienced favorable nutritional and perioperative outcomes., (Copyright © 2024 Elsevier Inc. All rights reserved.)- Published
- 2024
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9. Learning curve of laparoscopic appendectomy in a low-resource setting: a cumulative sum analysis of operative length.
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Ndong A, Diallo AC, Rouhi AD, Diao ML, Leon S, Dia DA, Alberstadt AN, Tendeng JN, Williams NN, Cissé M, Dumon KR, and Konaté I
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- Humans, Female, Male, Adult, Adolescent, Prospective Studies, Middle Aged, Child, Young Adult, Aged, Senegal, Developing Countries, Postoperative Complications epidemiology, Postoperative Complications etiology, Length of Stay statistics & numerical data, Appendectomy methods, Appendectomy education, Learning Curve, Laparoscopy education, Laparoscopy methods, Operative Time, Appendicitis surgery
- Abstract
Background: Cumulative sum (CUSUM) analysis is a valuable tool for quantifying the learning curve of surgical teams by detecting significant changes in operative length. However, there is limited research evaluating the learning curve of laparoscopic techniques in low-resource settings. The objective of this study is to evaluate the learning curve for laparoscopic appendectomy within a single surgical team in Senegal., Methods: This was a single-center prospective study conducted from May 1, 2018, to August 31, 2023 of patients who underwent laparoscopic appendectomy at a tertiary care institution in West Africa. The AAST classification was used to describe the severity of appendicitis. Parameters studied included age, sex, operative length, conversion rate, and postoperative outcomes. To quantify the learning curve, CUSUM analysis of operative length was performed., Results: A total of 81 patients were included. The mean age was 26.7 years (range 11-70 years) with a sex ratio of 1.9. Pre-operative severity according to AAST was Grade I in 75.4% (n = 61), Grade III in 7.4% (n = 6), Grade IV in 6.1% (n = 5), and Grade V in 11.1% (n = 9). Conversion occurred in 5 cases (6.1%). The average operative length was 76.8 min (range 30-180 min) and the average length of hospitalization was 2.7 days (range 1-13 days). Morbidity was observed in 3.7% (n = 3) and there were no deaths. The CUSUM analysis showed that a steady operative length was achieved after 28 procedures, with decreasing operative lengths thereafter., Conclusion: Surgeons in our setting overcame the learning curve for laparoscopic appendectomy after performing 28 procedures. Moreover, laparoscopic appendectomy is safe and feasible throughout the learning curve. CUSUM analysis should be applied to other laparoscopic procedures and individualized by surgical teams to improve surgical performance and patient outcomes in low-resource settings., (© 2024. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)
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- 2024
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10. Sleeve Gastrectomy Reduces the Need for Liver Transplantation in Patients with Obesity and Non-Alcoholic Steatohepatitis: a Predictive Model.
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Rouhi AD, Castle RE, Hoeltzel GD, Williams NN, Dumon KR, Baimas-George M, Wachs M, Nydam TL, and Choudhury RA
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- Humans, Obesity surgery, Weight Loss, Gastrectomy, Treatment Outcome, Non-alcoholic Fatty Liver Disease complications, Liver Transplantation, Obesity, Morbid surgery
- Abstract
Background: Non-alcoholic steatohepatitis (NASH) is one of the leading indications for liver transplantation (LT) in the United States. As with the current obesity epidemic, the incidence of NASH continues to rise. However, the impact of broad utilization of bariatric surgery (BS) for patients with NASH is unknown, particularly in regard to mitigating the need for LT., Methods: Markov decision analysis was performed to simulate the lives of 20,000 patients with obesity and concomitant NASH who were deemed ineligible to be waitlisted for LT unless they achieved a body mass index (BMI) < 35 kg/m
2 . Life expectancy following medical weight management (MWM) and sleeve gastrectomy (SG) were estimated. Base case patients were defined as having NASH without fibrosis and a pre-intervention BMI of 45 kg/m2 . Sensitivity analysis of initial BMI was performed., Results: Simulated base case analysis patients who underwent SG gained 14.3 years of life compared to patients who underwent MWM. One year after weight loss intervention, 9% of simulated MWM patients required LT compared to only 5% of SG patients. Survival benefit for SG was observed above a BMI of 32.2 kg/m2 ., Conclusion: In this predictive model of 20,000 patients with obesity and concomitant NASH, surgical weight loss is associated with a reduction in the progression of NASH, thereby reducing the need for LT. A reduced BMI threshold of 32 kg/m2 for BS may offer survival benefit for patients with obesity and NASH., (© 2024. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)- Published
- 2024
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11. A Systematic Review of Immersive Virtual Reality for Nontechnical Skills Training in Surgery.
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Yi WS, Rouhi AD, Duffy CC, Ghanem YK, Williams NN, and Dumon KR
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- Humans, Clinical Competence, Computer Simulation, Motion Sickness, Simulation Training methods, Virtual Reality
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Objective: Immersive virtual reality (IVR) can be utilized to provide low cost and easily accessible simulation on all aspects of surgical education. In addition to technical skills training in surgery, IVR simulation has been utilized for nontechnical skills training in domains such as clinical decision-making and pre-operative planning. This systematic review examines the current literature on the effectiveness of IVR for nontechnical skill acquisition in surgical education., Design: A literature search was performed using MEDLINE, EMBASE, and Web of Science for primary studies published between January 1, 1995 and February 9, 2022. Four reviewers screened titles, abstracts, full texts, extracted data, and analyzed included studies to answer 5 key questions: How is IVR being utilized in nontechnical skills surgical education? What is the methodological quality of studies? What technologies are being utilized? What metrics are reported? What are the findings of these studies?, Results: The literature search yielded 2340 citations, with 12 articles included for qualitative synthesis. Of included articles, 33% focused on clinical decision-making and 67% on anatomy/pre-operative planning. Motion sickness was a recorded metric in 25% of studies, with an aggregate incidence of 13% (11/87). An application score was reported in 33% and time to completion in 16.7%. A commercially developed application was utilized in 25%, while 75% employed a noncommercial application. The Oculus Rift was used in 41.7% of studies, HTC Vive in 25%, Samsung Gear in 16.7% of studies, Google Daydream in 8%, and 1 study did not report. The mean Medical Education Research Quality Instrument (MERSQI) score was 10.3 ± 2.3 (out of 18). In all studies researching clinical decision-making, participants preferred IVR to conventional teaching methods and in a nonrandomized control study it was found to be more effective. Averaged across all studies, mean scores were 4.33 for enjoyment, 4.16 for utility, 4.11 for usability, and 3.73 for immersion on a 5-point Likert scale., Conclusions: The IVR nontechnical skills applications for surgical education are designed for clinical decision-making or anatomy/pre-operative planning. These applications are primarily noncommercially produced and rely upon a diverse array of HMDs for content delivery, suggesting that development is primarily coming from within academia and still without clarity on optimal utilization of the technology. Excitingly, users find these applications to be immersive, enjoyable, usable, and of utility in learning. Although a few studies suggest that IVR is additive or superior to conventional teaching or imaging methods, the data is mixed and derived from studies with weak design. Motion sickness with IVR remains a complication of IVR use needing further study to determine the cause and means of mitigation., (Copyright © 2023 Association of Program Directors in Surgery. Published by Elsevier Inc. All rights reserved.)
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- 2024
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12. Ventricular Remodeling Following Metabolic and Bariatric Surgery Decreases Need for Heart Transplantation: A Predictive Model.
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Rouhi AD, Choudhury RA, Hoeltzel GD, Ghanem YK, Bababekov YJ, Suarez-Pierre A, Yule A, Vigneshwar NG, Williams NN, Dumon KR, and Nydam TL
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- Humans, Ventricular Remodeling, Obesity surgery, Gastrectomy methods, Retrospective Studies, Treatment Outcome, Obesity, Morbid surgery, Gastric Bypass methods, Bariatric Surgery, Heart Transplantation, Heart Failure surgery
- Abstract
Purpose: For patients with obesity and congestive heart failure (CHF) who require heart transplantation (HT), aggressive weight loss has been associated with ventricular remodeling, or subclinical alterations in left and right ventricular structure that affect systolic function. Many have suggested offering metabolic and bariatric surgery (MBS) for these patients. As such, we evaluated the role of MBS in HT for patients with obesity and CHF using predictive modelling techniques., Materials and Methods: Markov decision analysis was performed to simulate the life expectancy of 30,000 patients with concomitant obesity, CHF, and 30% ejection fraction (EF) who were deemed ineligible to be waitlisted for HT unless they achieved a BMI < 35 kg/m
2 . Life expectancy following diet and exercise (DE), Roux-en-Y gastric bypass (RYGB), and sleeve gastrectomy (SG) was estimated. Base case patients were defined as having a pre-intervention BMI of 45 kg/m2 . Sensitivity analysis of initial BMI was performed., Results: RYGB patients had lower rates of HT and received HT quicker when needed. Base case patients who underwent RYGB gained 2.2 additional mean years survival compared with patients who underwent SG and 10.3 additional mean years survival compared with DE. SG patients gained 6.2 mean years of life compared with DE., Conclusion: In this simulation of 30,000 patients with obesity, CHF, and reduced EF, MBS was associated with improved survival by not only decreasing the need for transplantation due to improvements in EF, but also increasing access to HT when needed due to lower average BMI., (© 2023. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)- Published
- 2024
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13. Factors associated with conversion in laparoscopic surgery in a low-resource setting: a single-center prospective study.
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Ndong A, Diallo AC, Rouhi AD, Diao ML, Yi W, Tendeng JN, Williams NN, Cissé M, Dumon KR, and Konaté I
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- Humans, Child, Adolescent, Young Adult, Adult, Middle Aged, Aged, Prospective Studies, Postoperative Complications epidemiology, Postoperative Complications etiology, Intraoperative Complications epidemiology, Intraoperative Complications etiology, Retrospective Studies, Laparoscopy adverse effects, Laparoscopy methods, Digestive System Surgical Procedures adverse effects
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Introduction: Laparoscopy has a clear patient benefit related to postoperative morbidity but may not be as commonly performed in low-and middle-income countries. The decision to convert to laparotomy can be complex and involve factors related to the surgeon, patient, and procedure. The objective of this work is to analyze the factors associated with conversion in laparoscopic surgery in a low-resource setting., Methods: This is a single-center prospective study of patients who underwent laparoscopic surgery between May 1, 2018 and October 31, 2021. The parameters studied were age, sex, body mass index (BMI), intraoperative complication (e.g., accidental enterotomy, hemorrhage), equipment malfunction (e.g., technical failure of the equipment, break in CO
2 supply line), operating time, and conversion rate., Results: A total of 123 laparoscopic surgeries were performed. The average age of patients was 31.2 years (range 11-75). The procedures performed included appendix procedures (48%), followed by gynecological (18.7%), gallbladder (14.6%), digestive (10.56%), and abdominal procedures (4%). The average length of hospitalization was 3 days (range 1-16). Conversion to laparotomy was reported in 8.9% (n = 11) cases. Equipment malfunction was encountered in 9.8% (n = 12) cases. Surgical complications were noted in 11 cases (8.9%). Risk factors for conversion were shown to be BMI > 25 kg/m2 (OR 4.6; p = 0.034), intraoperative complications (OR 12.6; p = 0.028), and equipment malfunction (OR 9.4; p = 0.002)., Conclusion: A better understanding of the underlying factors associated with high conversion rates, such as overweight/obesity, intraoperative complications, and equipment failure, is the first step toward surgical planning to reduce postoperative morbidity in low-resource settings., (© 2023. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)- Published
- 2023
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14. What are trainees watching? Assessing the educational quality of online laparoscopic cholecystectomy training videos using the LAP-VEGaS guidelines.
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Rouhi AD, Roberson JL, Kindall E, Ghanem YK, Ndong A, Yi WS, Williams NN, and Dumon KR
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- Humans, Reproducibility of Results, Educational Measurement, Educational Status, Cholecystectomy, Laparoscopic education, Laparoscopy education
- Abstract
Background: Laparoscopic cholecystectomy is the most common laparoscopic procedure performed in the US and a key component of general surgery training. Surgical trainees frequently access YouTube for educational walkthroughs of surgical procedures. This study aims to evaluate the educational quality of YouTube video walkthroughs on laparoscopic cholecystectomy by using the LAParoscopic surgery Video Educational GuidelineS (LAP-VEGaS) video assessment tool., Methods: A YouTube search was conducted using "laparoscopic cholecystectomy." Results were sorted by relevance, and the top 100 videos were gathered. Videos with patient education or concomitant procedures were excluded. Included videos were categorized as Physician (produced by an individual physician), Academic (produced by a university or medical school), Commercial (produced by a surgical company), and Society (produced by a professional surgical society) and were rated by 3 investigators using the LAP-VEGaS video assessment tool (0-18)., Results: In all, 33 videos met the selection criteria. The average LAP-VEGaS score was 7.96 ± 3.95, and inter-rater reliability was .86. Academic videos demonstrated a significantly higher mean LAP-VEGaS score than Commercial (10.69 ± 3.54 vs 5.25 ± 2.38, P = .033). Most academic videos failed to provide formal case presentations (63%), patient positioning (50%), intraoperative findings (50%), graphic aids (63%), and operative time (75%)., Conclusion: This is the first study to evaluate the quality of YouTube video walkthroughs on LC using the LAP-VEGaS tool. Despite demonstrating higher LAP-VEGaS scores than other categories, video walkthroughs provided by academic institutions still lack several essential educational criteria for this procedure, highlighting areas of improvement for educators., (Copyright © 2023 Elsevier Inc. All rights reserved.)
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- 2023
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15. Online information for incisional hernia repair: What are patients reading?
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Rouhi AD, Ghanem YK, Bader E, Hoeltzel GD, Joshi ART, Williams NN, and Dumon KR
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- United States, Humans, Benchmarking, Comprehension, Search Engine, Internet, Reading, Incisional Hernia surgery
- Abstract
Purpose: Patients increasingly access online materials for health-related information. Using validated assessment tools, we aim to assess the quality and readability of online information for patients considering incisional hernia (IH) repair., Methods: The top three online search engines (Google, Bing, Yahoo) were searched in July 2022 for "Incisional hernia repair" and "Surgical hernia repair". Included websites were classified as academic, hospital-affiliated, commercial, and unspecified. The quality of information was assessed using the Journal of the American Medical Association (JAMA) benchmark criteria (0-4), DISCERN instrument (16-80), and the presence of Health On the Net code (HONcode) certification. Readability was assessed using the Flesch Reading Ease (FRE) and Flesch-Kincaid Grade Level (FKGL) tests., Results: 25 unique websites were included. The average JAMA and DISCERN scores of all websites were 0.68 ± 1.02 and 36.50 ± 10.91, respectively. Commercial sites showed a significantly higher DISCERN mean score than academic sites (p = 0.034), while no significant difference was demonstrated between other website categories. 3 (12%) websites reported HONcode certification and had significantly higher JAMA (p = 0.016) and DISCERN (p = 0.045) mean scores than sites without certification. Average FRE and FKGL scores were 39.84 ± 13.11 and 10.62 ± 1.76, respectively, corresponding to college- and high school-level comprehensibility., Conclusions: Our findings suggest online patient resources on IH repair are of poor overall quality and may not be comprehensible to the public. Patients accessing internet resources for additional information on IH repair should be made aware of these inadequacies and directed to sites bearing HONcode certification., Competing Interests: Declarations of competing interest None., (Copyright © 2022 Royal College of Surgeons of Edinburgh (Scottish charity number SC005317) and Royal College of Surgeons in Ireland. Published by Elsevier Ltd. All rights reserved.)
- Published
- 2023
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16. Evaluation of the educational quality of publicly available online videos on laparoscopic jejunostomy by utilizing the LAP-VEGaS guidelines.
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Roberson JL, Rouhi AD, Bader AL, Yi WS, Williams NN, Morris JB, and Dumon KR
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- Humans, Jejunostomy, Video Recording, Educational Measurement, Laparoscopy education, Social Media
- Abstract
Background: Despite its common nature, there is no data on the educational quality of publicly available laparoscopic jejunostomy training videos. The LAParoscopic surgery Video Educational GuidelineS (LAP-VEGaS) video assessment tool, released in 2020, has been developed to ensure that teaching videos are of appropriate quality. This study applies the LAP-VEGaS tool to currently available laparoscopic jejunostomy videos., Methods: A retrospective review of YouTube
® videos was conducted for "laparoscopic jejunostomy." Included videos were rated by three independent investigators using LAP-VEGaS video assessment tool (0-18). Wilcoxon rank-sum test was used to evaluate differences in LAP-VEGaS scores between video categories and date of publication relative to 2020. Spearman's correlation test was performed to measure association between scores and length, number of views and likes., Results: 27 unique videos met selection criteria. Academic and physician video walkthroughs did not demonstrate a significant difference in median scores (9.33 IQR 6.33, 14.33 vs. 7.67 IQR 4, 12.67, p = 0.3951). Videos published after 2020 demonstrated higher median scores than those published before 2020 (13 IQR 7.5, 14.67 vs. 5 IQR 3, 9.67, p = 0.0081). A majority of videos failed to provide patient position (52%), intraoperative findings (56%), operative time (63%), graphic aids (74%), and audio/written commentary (52%). A positive association was demonstrated between scores and number of likes (rs = 0.59, p = 0.0011) and video length (rs = 0.39, p = 0.0421), but not number of views (rs = 0.17, p = 0.3991)., Conclusion: The majority of available YouTube® videos on laparoscopic jejunostomy fail to meet the basic educational needs of surgical trainees, and there is no difference between those produced by academic centers or independent physicians. However, there has been improvement in video quality following the release of the scoring tool. Standardization of laparoscopic jejunostomy training videos with the LAP-VEGaS score can ensure that videos are of appropriate educational value with logical structure., (© 2023. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)- Published
- 2023
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17. Evolution of laparoscopic surgery in a sub-Saharan African country: a 30-year literature review in Senegal.
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Ndong A, Diallo AC, Rouhi AD, Diao ML, Yi W, Tendeng JN, Williams NN, Cissé M, Dumon KR, and Konaté I
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- Humans, Child, Preschool, Child, Adolescent, Young Adult, Adult, Middle Aged, Senegal, Morbidity, Laparoscopy methods, Hernia, Inguinal surgery
- Abstract
Introduction: The advent of laparoscopy has significantly reduced the morbidity associated with the majority of abdominal surgeries. In Senegal, the first studies evaluating this technique were published in the 1980s. The objective of this systematic review is to assess the evolution of laparoscopy research in Senegal., Methods: A search of PubMed and Google Scholar was carried out without limit of publication date. The keywords used were "senegal" AND "laparoscop*". Duplicates were removed, and remaining articles were assessed for selection criteria. We included all articles about laparoscopy published in Senegal. The parameters studied in each included article were the place and year of study, average age, sex ratio, assessed indications and results., Results: 41 Studies published between 1984 and 2021 met selection criteria. The average age of patients was 33 years (range 4.7-63). The sex ratio was 0.33. The main indications for laparoscopy according to the studies were: benign gastrointestinal disorders in 11 studies (26.8%), abdominal emergencies in 9 studies (22%), gallbladder surgery in 5 studies (12.2%), benign gynecological pathology in 6 studies (14.6%), malignant gynecological pathology in 2 studies (4.9%), diagnostic laparoscopy in 2 studies (4.9%), groin hernia repair in 2 studies (4.9%) and testicular pathology in 1 study (2.4%). Overall mortality was estimated at 0.9% (95% CI 0.6-1.3) and overall morbidity for all complications was estimated at 5% (95% CI 3.4-6.9)., Conclusions: This systematic review showed a predominance of the laparoscopy publications from the capital in Dakar with favorable outcomes. This technique should be popularized in the different regions of the country and its indications expanded., (© 2023. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)
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- 2023
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18. Conversion to Roux-En-Y Gastric Bypass: a successful means of mitigating reflux after laparoscopic sleeve gastrectomy.
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Strauss AL, Triggs JR, Tewksbury CM, Soriano I, Wernsing DS, Dumon KR, Williams NN, and Shao JM
- Subjects
- Humans, Female, Adult, Middle Aged, Male, Gastrectomy methods, Reoperation, Retrospective Studies, Weight Loss, Proton Pump Inhibitors, Treatment Outcome, Gastric Bypass methods, Obesity, Morbid surgery, Laparoscopy methods, Gastroesophageal Reflux etiology, Gastroesophageal Reflux prevention & control, Gastroesophageal Reflux surgery
- Abstract
Introduction: Laparoscopic sleeve gastrectomy (LSG) has become the most common bariatric procedure due to the technical ease and weight loss success of the operation. However, there has been concern that LSG contributes to gastroesophageal reflux disease (GERD) postoperatively with a proportion of patients requiring conversion to a Roux-En-Y Gastric Bypass (RYGB). The objective of this study was to characterize the patients who underwent revision in our hospital system and to better understand pre-operative predictors of GERD and revision., Methods: After IRB approval, a retrospective review was conducted assessing for patients who had conversion of LSG to RYGB at three hospitals within the University of Pennsylvania Health System from January 2015 to December 2021. The patients' charts were then reviewed to evaluate for demographics, BMI, operative findings, imaging and endoscopic reports, and post-operative outcomes., Results: 97 patients were identified who underwent conversion of LSG to RYGB between January 2015 and December 2021. The cohort was predominantly female (n = 89, 91.7%) with an average age of 42.7 ± 10.6 years at the time of conversion. The most common indications for revision were GERD (72.2%) and obesity/insufficient weight loss (24.7%). Patients lost an average of 11.1 ± 12.9 kg after revision to RYGB. Of the patients who underwent revision for GERD, 80.2% noted global symptomatic improvement after revision and 19.4% were able to stop their proton pump inhibitor (PPI) postoperatively, with most patients decreasing the frequency of the PPI use postoperatively., Conclusion: The majority of patients who underwent conversion from LSG to RYGB due to GERD and saw marked improvements in GERD symptoms and outcomes. These findings illuminate the real-world practices and outcomes of bariatric revisional procedures for reflux and the need for more research on standardized practice., (© 2023. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)
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- 2023
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19. Quality and readability of online patient information on the left ventricular assist device.
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Rouhi AD, Han JJ, Ghanem YK, Pervaiz SS, Suarez-Pierre A, Choudhury RA, Bermudez CA, Williams NN, and Dumon KR
- Subjects
- Humans, Benchmarking, Comprehension, Heart-Assist Devices
- Abstract
Background: As patients seek online health information to supplement their medical decision-making, the aim of this study is to assess the quality and readability of internet information on the left ventricular assist device (LVAD)., Methods: Three online search engines (Google, Bing, and Yahoo) were searched for "LVAD" and "Left ventricular assist device." Included websites were classified as academic, foundation/advocacy, hospital-affiliated, commercial, or unspecified. The quality of information was assessed using the JAMA benchmark criteria (0-4), DISCERN tool (16-80), and the presence of Health On the Net code (HONcode) accreditation. Readability was assessed using the Flesch Reading Ease score., Results: A total of 38 unique websites were included. The average JAMA and DISCERN scores of all websites were 0.82 ± 1.11 and 52.45 ± 13.51, respectively. Academic sites had a significantly lower JAMA mean score than commercial (p < 0.001) and unspecified (p < 0.001) websites, as well as a significantly lower DISCERN, mean score than commercial sites (p = 0.002). HONcode certification was present in 6 (15%) websites analyzed, which had significantly higher JAMA (p < 0.001) and DISCERN (p < 0.016) mean scores than sites without HONcode certification. Readability was fairly difficult and at the level of high school students., Conclusions: The quality of online information on the LVAD is variable, and overall readability exceeds the recommended level for the public. Patients accessing online information on the LVAD should be referred to sites with HONcode accreditation. Academic institutions must provide higher quality online patient literature on LVADs., (© 2022 International Center for Artificial Organ and Transplantation (ICAOT) and Wiley Periodicals LLC.)
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- 2023
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20. Uncontrolled donation after cardiac death kidney transplantation: Opportunity to expand the donor pool?
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Rouhi AD, Choudhury RA, Hoeltzel GD, Prins K, Yoeli D, Moore HB, Williams NN, Dumon KR, and Nydam TL
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- Humans, Delayed Graft Function, Tissue Donors, Death, Kidney, Graft Survival, Brain Death, Retrospective Studies, Kidney Transplantation, Tissue and Organ Procurement
- Abstract
Background: Compared to controlled donation after cardiac death (cDCD), uncontrolled DCD (uDCD) kidney transplantation remains an underutilized resource in the United States. However, it is unclear whether long-term allograft outcomes following uDCD are inferior to that of cDCD kidney transplantation., Methods: From January 1995 to January 2018, the OPTN/UNOS database was queried to discover all reported cases of uDCD and cDCD kidney transplantation. Primary non-function, delayed graft function, ten-year graft and patient survival were compared among uDCD and cDCD patients., Results: Rates of primary non-function (4.0% [uDCD] vs. 1.8% [cDCD], P < 0.001) and delayed graft function (51.1% [uDCD] vs. 41.7% [cDCD], P < 0.001) were higher following uDCD transplant. However, ten-year graft survival (47.5% [uDCD] vs. 48.4% [cDCD], P = 0.21) and patient survival were similar to cDCD transplantation (59.4% [uDCD] vs. 59.2% [cDCD], P = 0.32)., Conclusion: Although initial allograft outcomes are inferior following uDCD, long-term durability of uDCD kidney allografts is on par to cDCD transplantation. Kidney allografts derived by uDCD may be a viable and durable option to increase the donor pool., Competing Interests: Declaration of competing interest All authors have no conflicts of interest to declare., (Copyright © 2022 Elsevier Inc. All rights reserved.)
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- 2023
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21. Delayed CRS-HIPEC Is Associated with Decreased Survival in Patients with Malignant Peritoneal Mesothelioma: A Markov Decision Analysis.
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Rouhi AD, Choudhury RA, Hoeltzel GD, Yule A, Williams NN, Dumon KR, and Karakousis GC
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- Humans, Hyperthermic Intraperitoneal Chemotherapy, Decision Support Techniques, Cytoreduction Surgical Procedures, Antineoplastic Combined Chemotherapy Protocols, Combined Modality Therapy, Survival Rate, Retrospective Studies, Mesothelioma, Malignant, Mesothelioma therapy, Mesothelioma pathology, Peritoneal Neoplasms therapy, Hyperthermia, Induced
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- 2023
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22. Changes in Eating Behaviors and Their Relation to Weight Change 6 and 12 Months After Bariatric Surgery.
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Allison KC, Wu J, Spitzer JC, McCuen-Wurst C, Ashare RL, Tewksbury C, LaGrotte CA, Wadden TA, Williams NN, and Sarwer DB
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- Humans, Female, Adult, Male, Feeding Behavior, Weight Loss physiology, Binge-Eating Disorder complications, Obesity, Morbid surgery, Bariatric Surgery
- Abstract
Introduction: Identifying eating behaviors associated with suboptimal weight loss following bariatric surgery remains important. This study assessed the relationship between eating behaviors and weight loss following bariatric surgery in a racially diverse sample., Methods: Participants were assessed before surgery and 6 and 12 months postoperatively, with the Structured Clinical Interview for DSM-5, the Eating Disorder Examination-Bariatric Surgery Version, and validated measures assessing a range of eating behaviors. Linear mixed effect models were used to test the impact of eating behaviors on percent weight loss (%WL) at 6 and 12 months., Results: We enrolled 300 participants (mean age 40.1 years; BMI 45.9 kg/m
2 ; 87% women; 62% Black and 30% White). The majority (82%) underwent sleeve gastrectomy (SG). Mean %WL was 23.0 ± 5.1% at 6 months and 26.2 ± 7.6% at 12 months. Subjective binge episodes prior to surgery predicted greater %WL over the first 12 postoperative months (p = 0.028). Postoperative disinhibition, hunger, night eating symptoms, objective binge episodes, global disordered eating attitudes and behaviors, and snacks per day were associated with smaller %WL over 12 months (all p's < 0.01). The presence of picking/nibbling and addictive-like eating behaviors was not associated with %WL at the end of the first postoperative year., Conclusion: Among a diverse participant sample, problematic eating behaviors following surgery were associated with smaller %WL over 12 months. Postoperative assessment and treatment of eating behaviors are needed to address these issues as they arise and to prevent attenuation of early weight loss in some patients., (© 2023. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)- Published
- 2023
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23. Online Resources for Patients Considering Hiatal Hernia Repair: a Quality and Readability Analysis.
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Rouhi AD, Ghanem YK, Hoeltzel GD, Bader E, Yi WS, Williams NN, and Dumon KR
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- Humans, Comprehension, Herniorrhaphy, Treatment Outcome, Retrospective Studies, Gastroesophageal Reflux surgery, Hernia, Hiatal surgery, Laparoscopy
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- 2023
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24. Quality and readability assessment of online patient information on cytoreductive surgery and hyperthermic intraperitoneal chemotherapy.
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Rouhi AD, Ghanem YK, Hoeltzel GD, Miura JT, Aarons CB, Williams NN, Dumon KR, and Karakousis GC
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- Humans, Cytoreduction Surgical Procedures, Search Engine, Internet, Hyperthermic Intraperitoneal Chemotherapy, Comprehension
- Abstract
Background and Objectives: We aim to assess the quality and readability of online information available to patients considering cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (CRS-HIPEC)., Methods: The top three search engines (Google, Bing, and Yahoo) were searched in March 2022. Websites were classified as academic, hospital-affiliated, foundation/advocacy, commercial, or unspecified. Quality of information was assessed using the JAMA benchmark criteria (0-4) and DISCERN tool (16-80), and the presence of a Health On the Net code (HONcode) seal. Readability was evaluated using the Flesch Reading Ease score., Results: Fifty unique websites were included. The average JAMA and DISCERN scores of all websites were 0.72 ± 1.14 and 39.58 ± 13.71, respectively. Foundation/advocacy websites had significantly higher JAMA mean score than commercial (p = 0.044), academic (p < 0.001), and hospital-affiliated websites (p = 0.001). Foundation/advocacy sites had a significantly higher DISCERN mean score than hospital-affiliated (p = 0.035) and academic websites (p = 0.030). The HONcode seal was present in 4 (8%) websites analyzed. Readability was difficult and at the level of college students., Conclusions: The overall quality of patient-oriented online information on CRS-HIPEC is poor and available resources may not be comprehensible to the general public. Patients seeking information on CRS-HIPEC should be directed to sites affiliated with foundation/advocacy organizations., (© 2022 Wiley Periodicals LLC.)
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- 2023
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25. Quality and Readability of Online Patient Information on Adolescent Bariatric Surgery.
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Rouhi AD, Ghanem YK, Hoeltzel GD, Yi WS, Collins JL, Prout EP, Williams NN, and Dumon KR
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- Humans, Adolescent, Comprehension, Internet, Obesity, Morbid surgery, Health Literacy, Consumer Health Information, Bariatric Surgery
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- 2023
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26. Pulling Back from the Brink: A Multi-Pronged Approach to Address General Surgery Resident Clinical Work Hour Adherence.
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Acker R, Swendiman RA, Luks VL, Hanna AN, Lee MK, Williams NN, Kelz RR, Lynn J, and Aarons CB
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- Humans, Education, Medical, Graduate, Accreditation, Data Collection, Workload, Internship and Residency
- Abstract
Purpose: The conflict between prioritizing education for surgical trainees, promoting trainee wellness, and maintaining optimal patient care has remained challenging since the introduction of the Accreditation Council for Graduate Medical Education (ACGME) work hour restrictions in 2003. There is still a dearth of research examining which interventions successfully enable duty hour adherence. This study assessed the impact of a combination of strategic interventions on improving clinical work hour adherence., Methods: Monthly clinical work hour submission rates were assessed for all general surgery residents at a single university-based residency program over a 3-year period (2018-2021). Interventions targeted 3 domains and were implemented between academic years 2018 to 2019 (control) and 2020 to 2021 (intervention): 1) improving the accuracy and transparency of work hour reporting, 2) facilitating more timely interventions, and 3) structural scheduling changes. All 80-hour work week and continuous work hour violations were assessed. Findings were also compared to the corresponding ACGME Resident Survey results., Results: There was no significant difference in the rate of monthly work hour submissions pre- and postintervention (78% vs 75%, p = 0.057). However, the number of total reported monthly violations decreased significantly (mean 13.8 vs 2.4, p < 0.01), including decreases in both 80-hour work week and continuous work hour violations (mean 4.7 vs 1.6, p < 0.001 and 9.1 vs 0.8, p < 0.001, respectively). Reported compliance also increased on the annual ACGME resident surveys, where 61% vs 95% of residents felt they were compliant with the 80-hour work week and 71% vs 95% felt they were compliant with the continuous work hours (2018-19 vs 2020-21)., Conclusion: Innovative strategies addressing schedule changes, the culture of work hour reporting, and early intervention significantly decreased the number of duty hour violations at our institution. Reported resident compliance also improved based on ACGME Resident Survey data. These data may inform similar multifaceted approaches at other institutions to improve overall work hour adherence., (Copyright © 2022 Association of Program Directors in Surgery. Published by Elsevier Inc. All rights reserved.)
- Published
- 2022
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27. How safe is adolescent bariatric surgery? An analysis of short-term outcomes.
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Hoeltzel GD, Swendiman RA, Tewksbury CM, Parks EP, Williams NN, and Dumon KR
- Subjects
- Adolescent, Adult, Child, Gastrectomy, Humans, Retrospective Studies, Treatment Outcome, Young Adult, Bariatric Surgery adverse effects, Gastric Bypass adverse effects, Obesity, Morbid surgery, Pediatric Obesity epidemiology, Pediatric Obesity surgery
- Abstract
Background: The prevalence of childhood obesity in the U.S. has tripled over the last three decades. However, fewer than 1% of children with severe obesity undergo surgical weight loss interventions each year., Materials and Methods: All patients age 10 to 19 years old who underwent laparoscopic Roux-en-Y gastric bypass (RYGB) or sleeve gastrectomy (SG) from 2015 through 2018 in the Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program database were included in this retrospective cohort analysis. The primary outcomes were mortality and overall complications. Procedural trends, readmission and reoperation rates were also examined using a multivariate regression model., Results: Patients had a mean BMI of 47.3 kg/m
2 and 80.0% were either 18 or 19 years old (n = 4,051). There were two reported deaths. Reoperation within 30 days occurred in 1.1% of patients, readmission in 3.5%, and complications in 1.2%. Among all readmissions, primary reasons included nausea/vomiting or nutritional depletion (41.3%) and abdominal pain (16.3%). RYGB was associated with higher odds for readmission (p = 0.006) and complications (p = 0.005). Higher BMI and younger age were not associated with an increased likelihood to experience poorer outcomes. The proportion of patients undergoing SG increased yearly over RYGB from 73.9% in 2015 to 84.3% in 2018., Conclusions: Bariatric surgery appears to be low risk for adolescents and SG has become the operation of choice. More research on early consideration of surgical therapy in adolescents with severe obesity is needed given the safety profile., Level of Evidence: III., Competing Interests: Disclosures The authors have no financial interests to disclose. This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors. All authors have approved this final article for submission., (Copyright © 2021 Elsevier Inc. All rights reserved.)- Published
- 2022
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28. Binge eating disorder and eating self-efficacy in adults seeking bariatric surgery.
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Chao AM, Abene J, Allison KC, Pearl RL, Wadden TA, Williams NN, and Tronieri JS
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- Adult, Cross-Sectional Studies, Depression psychology, Female, Humans, Male, Middle Aged, Self Efficacy, Bariatric Surgery psychology, Binge-Eating Disorder psychology, Obesity, Morbid psychology, Obesity, Morbid surgery
- Abstract
This study assessed the relationships between binge eating disorder (BED) and eating self-efficacy in a sample of patients prior to bariatric surgery. The study also examined the extent that BED status accounted for variance in self-efficacy after controlling for demographic factors (age, sex and race), physical variables (comorbidities and body mass index [BMI]) and depressive symptoms. This was a cross-sectional study of pre-surgical data from patients seeking bariatric surgery at a university-based healthcare system (N = 98; mean ± SD age of 46.2 ± 12.5 years; BMI of 45.4 ± 7.2 kg/m
2 ; 86.7% female; and 60.2% of patients self-identified as White). Patients completed the Weight and Lifestyle Inventory (WALI), Beck Depression Inventory-II (BDI-II) and Weight Efficacy Lifestyle Questionnaire. Of the total sample, 15.3% met criteria for BED, 33.7% had subthreshold BED and 51.0% were free of this disorder. In adjusted analyses, total self-efficacy was significantly lower in patients with subthreshold BED (B ± SE = -15.88 ± 7.23, p = .03) and individuals with BED (B ± SE = -35.07 ± 10.23, p = .001) than in those without BED. Patients with BED, compared to those without, had significantly worse scores (in adjusted analyses) on the self-efficacy subscales of negative emotions (p = .003), availability of food (p < .001), social pressure (p = .004) and positive activities (p = .03). In patients seeking bariatric surgery, total self-efficacy scores were significantly lower in patients with BED and subthreshold BED than those without BED. The results suggest that eating self-efficacy may be an important factor to target in patients with BED who seek bariatric surgery., (© 2022 World Obesity Federation.)- Published
- 2022
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29. The Effects of the Affordable Care Act on Utilization of Bariatric Surgery.
- Author
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Brooks ES, Bailey EA, Mavroudis CL, Wirtalla CJ, Gershuni VM, Williams NN, and Kelz RR
- Subjects
- Humans, Insurance Coverage, Insurance, Health, Medicaid, Patient Protection and Affordable Care Act, United States epidemiology, Bariatric Surgery, Obesity, Morbid surgery
- Abstract
Introduction: The Affordable Care Act (ACA) expanded Medicaid (ME) and instituted Essential Health Benefits (EHB) that included bariatric surgery coverage on a state-by-state opt-in basis, increasing insurance coverage of bariatric surgery., Materials and Methods: Using a difference-in-differences framework, changes in bariatric surgery rates, defined as utilization in the population of people with obesity, before and after the ACA were evaluated in four states. Bariatric surgery procedure data were taken from the Healthcare Cost and Utilization Project's State In-patient Database 2012-2015. Adjusted multivariable regressions were run in the Medicaid and commercially insured populations., Results: We identified 36,456 bariatric surgeries across the 286 Health Service Areas and time periods, with 31,732 covered by commercial insurers and 4724 covered by Medicaid. An unadjusted increase in utilization rates was seen in the Medicaid and Commercial populations in both ME- and EHB-covered states as well as non-expansion and EHB opt-out states over time. In the Medicaid population, after adjusting for confounders, there was a significant increase of 24.77 cases per 100,000 people with obesity (95% confidence interval: 12.41, 37.13) in the expansion states relative to the control and pre-period. The commercial population experienced a nonsignificant change in the rates of bariatric surgery, decreasing by 2.89 cases per 100,000 people with obesity (95% confidence interval: - 21.59, 15.81)., Conclusions: There was a significant increase in bariatric surgery rates among Medicaid beneficiaries associated with Medicaid expansion, but there was no change among the commercially insured., (© 2021. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)
- Published
- 2021
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30. American Society for Metabolic and Bariatric Surgery: Preoperative Care Pathway for Laparoscopic Roux-en-Y Gastric Bypass.
- Author
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Kindel TL, Ganga RR, Baker JW, Noria SF, Jones DB, Omotosho P, Volckmann ET, Williams NN, Telem DA, Petrick AT, and Gould JC
- Subjects
- Humans, Preoperative Care, United States, Bariatric Surgery, Gastric Bypass, Laparoscopy
- Published
- 2021
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31. Practical considerations of developing and conducting a successful telehealth practice in response to COVID-19.
- Author
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Tewksbury C, Deleener ME, Dumon KR, and Williams NN
- Subjects
- Academic Medical Centers, Humans, Pandemics, SARS-CoV-2, COVID-19, Telemedicine
- Abstract
The coronavirus disease 2019 (COVID-19) pandemic posed significant challenges to clinicians practicing in outpatient settings focused on chronic disease treatment and management. Many interprofessional teams transitioned to telehealth to continue to provide care while minimizing in-person interaction to reduce risk of transmission. Given that telehealth will likely remain as a care option even as the pandemic subsides, this review summarizes the applied recommendations on telehealth in interprofessional patient care, provides practical insights for successfully transitioning care from an academic medical center bariatric surgery program, and highlights future opportunities for research., (© 2021 American Society for Parenteral and Enteral Nutrition.)
- Published
- 2021
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32. Risk factors for postdischarge venous thromboembolism among bariatric surgery patients and the evolving approach to extended thromboprophylaxis with enoxaparin.
- Author
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O'Connor K, Garcia Whitlock AE, Tewksbury C, Williams NN, and Dumon KR
- Subjects
- Aftercare, Anticoagulants therapeutic use, Enoxaparin therapeutic use, Humans, Male, Patient Discharge, Risk Factors, Bariatric Surgery adverse effects, Venous Thromboembolism etiology, Venous Thromboembolism prevention & control
- Abstract
Background: Venous thromboembolism (VTE) is one of the most common causes of postoperative mortality following bariatric surgery. The majority of VTE events occur after discharge from the hospital. Little consensus exists regarding who should receive extended enoxaparin thromboprophylaxis or how they should be dosed, namely whether to use weight-based or BMI-stratified dosing strategies., Objectives: Provide an overview of the risk factors associated with VTE in procedures among bariatric patients including the use of predictive tools to stratify risk and the various approaches to enoxaparin chemoprophylaxis in obesity., Setting: Multiple centers., Methods: A review of the literature identified studies evaluating risk factors for VTE including demographic characteristics, co-morbidities, and operative factors. The use of calculators to stratify patients by risk and approaches to extended thromboprophylaxis in obesity were evaluated as well., Results: VTE was associated with increased age, weight, male sex, and prior history of VTE, all frequently included in risk calculators. Outside of those major risk factors, there is little consensus about the importance of patient diagnoses. Weight-based dosing was often superior to standardized dosing in studies across disciplines in generating target anti-Xa levels however there is no consistent association of reduced risk of VTE with therapeutic anti-Xa levels., Conclusions: Risk calculators may be a valuable tool for identifying patients at high-risk for VTE, but their efficacy depends on the rating algorithm and inclusion of various risk factors and is methodologically limited by prophylactic interventions. Future work should consider if biochemical factors should be included in patient stratification approaches in particular when defining the ideal chemoprophylaxis approach. Transparency and consistency in data collection and reporting is needed to better assess and inform the ideal dosing strategy to prevent VTE following bariatric surgery., (Copyright © 2021 American Society for Bariatric Surgery. Published by Elsevier Inc. All rights reserved.)
- Published
- 2021
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33. Modified Metabolic Syndrome Predicts Worse Outcomes in Obese Patients Undergoing Inguinal Hernia Repair.
- Author
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Shannon AB, Kelz RR, Williams NN, Karakousis GC, and Dumon KR
- Subjects
- Herniorrhaphy, Humans, Obesity complications, Hernia, Inguinal surgery, Laparoscopy, Metabolic Syndrome complications, Metabolic Syndrome epidemiology
- Published
- 2021
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34. Psychopathology, disordered eating, and impulsivity in patients seeking bariatric surgery.
- Author
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Sarwer DB, Wadden TA, Ashare RL, Spitzer JC, McCuen-Wurst C, LaGrotte C, Williams NN, Edwards M, Tewksbury C, Wu J, Tajeu G, and Allison KC
- Subjects
- Depression, Humans, Impulsive Behavior, Surveys and Questionnaires, Bariatric Surgery, Depressive Disorder, Major, Feeding and Eating Disorders epidemiology, Obesity, Morbid surgery
- Abstract
Background: Most patients who undergo bariatric surgery experience significant weight loss and improvements in obesity-related co-morbidities in the first 6-18 months after surgery. However, 20%-30% of patients experience suboptimal weight loss or significant weight regain within the first few postoperative years. Psychosocial functioning may contribute to suboptimal weight loss and/or postoperative psychosocial distress., Objective: Assess psychosocial functioning, eating behavior, and impulsivity in patients seeking bariatric surgery., Setting: Two university hospitals., Methods: Validated interviews and questionnaires. Impulsivity assessed via computer program., Results: The present study included a larger (n = 300) and more racially diverse (70% non-White) sample than previous studies of these relationships. Forty-eight percent of participants had a current psychiatric diagnosis and 78% had at least 1 lifetime diagnosis. Anxiety disorders were the most common current diagnosis (25%); major depressive disorder was the most common lifetime diagnosis (44%). Approximately 6% of participants had a current alcohol or substance use disorder; 7% had a positive drug screen before surgery. A current psychiatric diagnosis was associated with greater symptoms of food addiction and night eating. Current diagnosis of alcohol use disorder or a lifetime diagnosis of anxiety disorders was associated with higher delay discounting., Conclusion: The study identified high rates of psychopathology and related symptoms among a large, diverse sample of bariatric surgery candidates. Psychopathology was associated with symptoms of disordered eating and higher rates of delay discounting, suggesting impulse control issues., (Copyright © 2020. Published by Elsevier Inc.)
- Published
- 2021
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35. The efficacy and safety of definitive concurrent chemoradiotherapy for non-operable esophageal cancer.
- Author
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Dreyfuss AD, Barsky AR, Wileyto EP, Eads JR, Kucharczuk JC, Williams NN, Karasic TB, Metz JM, Ben-Josef E, Plastaras JP, and Wojcieszynski AP
- Subjects
- Adenocarcinoma pathology, Adult, Aged, Aged, 80 and over, Antineoplastic Combined Chemotherapy Protocols adverse effects, Carboplatin administration & dosage, Carboplatin adverse effects, Chemoradiotherapy, Cohort Studies, Esophageal Neoplasms pathology, Esophageal Squamous Cell Carcinoma pathology, Female, Fluorouracil administration & dosage, Fluorouracil adverse effects, Humans, Male, Middle Aged, Paclitaxel administration & dosage, Paclitaxel adverse effects, Radiotherapy Dosage, Retrospective Studies, Survival Rate, Adenocarcinoma drug therapy, Adenocarcinoma radiotherapy, Antineoplastic Combined Chemotherapy Protocols therapeutic use, Esophageal Neoplasms drug therapy, Esophageal Neoplasms radiotherapy, Esophageal Squamous Cell Carcinoma drug therapy, Esophageal Squamous Cell Carcinoma radiotherapy
- Abstract
Objective: To report outcomes and toxicity in patients who received definitive concurrent chemoradiation (DCCRT) for non-operable esophageal cancer (EC) in the modern era, and to identify markers of overall and disease-free survival (OS/DFS)., Methods: We conducted a retrospective cohort study of patients with unresectable EC who received DCCRT at our institution between 1/2008 and 1/2019. Descriptive statistics were used to report disease-control outcomes and CTCAE v4.0-5.0 toxicities. Univariable and multivariable Cox regression, and stepwise regression were used to identify associations with survival., Results: At a median follow-up of 19.5 months, 130 patients with adenocarcinoma (AC) (62%) or squamous cell carcinoma (SCC) (38%) were evaluable (Stage II-III: 92%). Patients received carboplatin/paclitaxel (75%) or fluorouracil-based (25%) concurrent chemotherapy. Median total RT dose was 50.4 Gy (range, 44.7-71.4 Gy) delivered in 28 fractions (24-35). Locoregional and distant recurrence occurred in 30% and 35% of AC, and 24% and 33% of SCC, respectively. Median OS and DFS were 22.9 and 10.7 months in AC, and 25.7 and 20.2 months in SCC, respectively. On stepwise regression, tumor stage, feeding tube during DCCRT, and change in primary tumor PET/CT SUVmax were significantly associated with OS and DFS. Most severe toxicities were acute grade 4 hematologic cytopenia (6%) and radiation dermatitis (1%). Most common acute grade 3 toxicities were hematologic cytopenia (35%), dysphagia (23%), and anorexia (19%)., Conclusions: Treatment of non-operable EC with DCCRT has acceptable toxicity and can provide multi-year disease control for some patients, even in AC. Continued follow-up and investigation in large studies would be useful., (© 2021 The Authors. Cancer Medicine published by John Wiley & Sons Ltd.)
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- 2021
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36. Can We Coach Resilience? An Evaluation of Professional Resilience Coaching as a Well-Being Initiative for Surgical Interns.
- Author
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Song Y, Swendiman RA, Shannon AB, Torres-Landa S, Khan FN, Williams NN, Dumon KR, Brooks AD, DeMatteo RP, and Aarons CB
- Subjects
- Female, Health Personnel, Humans, Male, Personal Satisfaction, Burnout, Professional prevention & control, Internship and Residency, Mentoring
- Abstract
Objective: The purpose of this study was to evaluate the use of a professionally trained, resilience coach for surgical interns., Design: Mixed-methods study with pre- and postcoaching quantitative surveys measuring burnout and resilience factors and semistructured interviews., Setting: General, Vascular, Cardiac, Plastic, and Urologic Surgery residencies at a tertiary academic center., Participants: Categorical and preliminary interns (N = 25) participated in a year-long, 8-session resilience coaching program for the academic year 2018 to 2019., Results: Program participants included 17 (68%) men and 8 (32%) women. The precoaching survey administered to interns before the start of the program identified 60% at risk of burnout as measured by the Abbreviated Maslach Burnout Inventory. The mean (standard deviation) Brief Resilience Scale score was 3.8 (0.8), with a trend toward a higher score (greater resilience) among men compared to women (4.1 [0.7] vs 3.4 [1.0], p = 0.10). Following the completion of the coaching program, the mean (standard deviation) Brief Resilience Scale score increased significantly from 3.8 [0.8] to 4.2 [0.7] p = 0.002). There were no changes in other parameters measuring burnout, satisfaction with life, or positive/negative affect. In semistructured interviews (N = 16/25 participants), most interns believed the coaching experience provided useful skills, but expressed concern about the durability of a 1-year intervention. Additionally, leadership-driven wellness at work, including optimizing team dynamics and purpose-driven engagement, were emphasized., Conclusions: About 60% of new interns at our institution were at risk of burnout. The coaching program was viewed positively and was effective in improving resilience. While this intervention was a useful first step, it should be incorporated into a longitudinal wellness program for the duration of surgical training., (Copyright © 2020 Association of Program Directors in Surgery. Published by Elsevier Inc. All rights reserved.)
- Published
- 2020
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37. Reliability of acoustic radiation force impulse shear wave elastography in the evaluation of liver stiffness in morbidly obese patients.
- Author
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Chauhan A, Shamchi SP, Dumon KR, Williams NN, and Sehgal CM
- Subjects
- Adult, Aged, Female, Humans, Male, Middle Aged, Prospective Studies, Reproducibility of Results, Young Adult, Body Mass Index, Elasticity Imaging Techniques methods, Liver diagnostic imaging, Obesity, Morbid diagnosis
- Abstract
Purpose: To evaluate technical and patient-related factors that can affect the reliability of acoustic radiation force impulse shear wave elastography (ARFI-SWE) in morbidly obese patients., Methods: A prospective single-center study was performed on 41 patients (32 females, 78%) presenting for preoperative evaluation for bariatric surgery. ARFI-SWE was performed using a 6 to 1.5 MHz curved (6C1) transducer. Hepatic steatosis was mild, moderate, severe, and absent in 24.4%, 12.2%, 43.9%, and 19.5% of patients, respectively. Interquartile range/median (IQR/M) ranged from 0.05 to 2.07 (0.78 ± 0.56 m/s). Twenty patients (48.7%) had reliable measurements (IQR/M < 0.3). Shear wave velocity (SWV) values were >1.34 m/s (clinically significant fibrosis) in 25 of 41 patients (61%) and >2.2 m/s (advanced fibrosis) in 19 patients (46%)., Results: Median SWV was correlated with body mass index (BMI; correlation coefficient [CC] = .37; 95% CI, 0.07-0.61; P-value = .03) and skin-to-liver capsule distance (SLD) (CC = .38; 95% CI, 0.09-0.62; P-value = .01). IQR/M was higher in patients with BMI > 40 (0.24 ± 0.11 vs 0.39 ± 0.25, P-value = .031) and SLD > 3 cm (0.46 ± 0.27 vs 0.23 ± 0.08, P-value = .001), and there was higher number of unreliable examinations among patient with SLD > 3 cm (16/23 vs 5/18, P-value = .01)., Conclusion: ARFI-SWE is technically more challenging among patients with higher BMI and SLD, resulting in a higher number of unreliable studies, which highlights the need for further advancement of ARFI technology., (© 2020 Wiley Periodicals, Inc.)
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- 2020
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38. Reverse epidemiology and the obesity paradox for patients with chronic kidney disease: a Markov decision model.
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Choudhury RA, Yoeli D, Moore HB, Yaffe H, Hoeltzel GD, Dumon KR, Williams NN, Abt PL, Conzen KD, and Nydam TL
- Subjects
- Gastrectomy, Humans, Middle Aged, Obesity complications, Obesity epidemiology, Weight Loss, Gastric Bypass, Obesity, Morbid complications, Obesity, Morbid surgery
- Abstract
Background: Obesity has been associated with both increased progression of chronic kidney disease (CKD) as well as with a paradoxical improvement in survival among end-stage renal disease patients undergoing hemodialysis. As such, the optimal weight management strategy for obese CKD patients remains unclear., Objective: To estimate the outcomes of obese, CKD stage 3b patients after 3 weight loss interventions, including medical weight management, sleeve gastrectomy (SG), and Roux-en-Y gastric bypass (RYGB), were followed to determine which strategy optimizes long-term survival., Setting: University hospital, Aurora, Colorado., Methods: A decision analytic Markov state transition model was created to simulate the life of 30,000 obese patients with CKD stage 3b, as they progressed to end-stage renal disease, transplantation, and death. Life expectancy after conservative medical weight management, RYGB, and SG were estimated. Base case patients were defined as being 50 years old and having a preintervention BMI of 40 kg/m
2 . Sensitivity analysis of initial BMI was performed. All Markov parameters were extracted from literature review., Results: RYGB and SG were associated with improved survival for patients with preintervention body mass index of >38 kg/m2 . Compared with conservative weight management, base case patients who underwent RYGB gained 10.6 months of life, and gained 8.3 months of life after SG., Conclusions: Balancing progression of CKD with improved survival on end-stage renal disease for obese patients requires selective use of weight management strategies. RYGB and SG improved survival for CKD patients with Class II and III obesity, but not for patients with Class I obesity. As such, aggressive weight loss interventions should be reserved for patients with Class II and III obesity, while more conservative methods should be offered to those with Class I obesity., (Copyright © 2020 American Society for Bariatric Surgery. Published by Elsevier Inc. All rights reserved.)- Published
- 2020
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39. Validation and improvement of a highly predictive bariatric surgery mortality risk calculator to include sleeve gastrectomy using MBSAQIP 2015-2017 data.
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Tewksbury C, Geng Z, Foster M, Gershuni V, Dumon KR, Rame JE, Groeneveld PW, and Williams NN
- Subjects
- Female, Gastrectomy, Humans, Middle Aged, Quality Improvement, Treatment Outcome, Bariatric Surgery, Obesity, Morbid surgery
- Abstract
Background: Initial development of a prominent bariatric surgery mortality risk calculator comprising cases that now account for <10% of commonly performed operations. Whether the previously highly predictive model is valid with more recent data is unknown., Objectives: To validate and improve a bariatric-surgery-specific mortality calculator with updated case mix and outcomes data., Setting: Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program-accredited bariatric surgery programs., Methods: The Metabolic and Bariatric Accreditation and Quality Improvement Program Participant Use File from years 2015 to 2017 was used for the analysis. C-statistics were calculated with observed death as the outcome and estimated 30-day mortality risk as the only predictor and receiver operating characteristic curve was plotted. Similar analyses were repeated for each body mass index (BMI) subgroup. Backward selection logistic regression was used to investigate the potential of improving the robustness of the model., Results: Patients were predominantly female (n = 446,149, 80.4%) and white (n = 409,350, 73.7%) with a mean (standard deviation) age of 45.4 (12.0) years and BMI of 44.5 (8.4) kg/m
2 , and the most commonly performed operation was sleeve gastrectomy (n = 338,061, 60.9%). Assessing previous model using present data, area under the curve was .7412. By BMI subgroup, area under the curve for BMI <45 kg/m2 was .7645, for BMI 45 to 60 kg/m2 was .7586, and for BMI >60 kg/m2 was .6576., Discussion: The present study found that the model previously developed maintains discrimination with changing surgical procedures. Though variables in the initial calculator are helpful, additional factors should be considered when weighing risk, such as sex, previous surgery, and renal function. Future studies are needed to determine whether changes in modifiable risk factors will impact mortality rates., (Copyright © 2020 American Society for Bariatric Surgery. Published by Elsevier Inc. All rights reserved.)- Published
- 2020
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40. Perspectives of adolescents with severe obesity on social Media in Preparation for weight-loss surgery: a qualitative study.
- Author
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Parks EP, Finnerty DD, Panganiban J, Frasso R, Bishop-Gilyard C, Tewksbury CM, Williams NN, Dumon KR, Cordero G, Hill DL, and Sarwer DB
- Subjects
- Adolescent, Female, Humans, Life Style, Male, Bariatric Surgery, Obesity, Morbid surgery, Social Media, Weight Loss
- Abstract
Background: Currently the most effective treatment for severe obesity in adolescents is weight-loss surgery coupled with lifestyle behavior change. In preparation for weight-loss surgery, adolescents are required to make changes to eating and activity habits (lifestyle changes) to promote long term success. Social media support groups, which are popular among adolescents, have the potential to augment preoperative lifestyle changes. The purpose of this study was to qualitatively assess the perceived role of social media as a support tool for weight-loss, and to identify motivators and constraints to lifestyle changes and social media use in adolescents preparing for weight-loss surgery., Methods: Thematic analysis of social media comments from 13 (3 male, 10 female) adolescents aged 16 ± 1.3 years with a body mass index (BMI) 45 ± 7.3 kg/m
2 enrolled in a weight-management program preparing for bariatric surgery and who participated in a 12-week pilot social media intervention was performed. Participants commented on moderator posts and videos of nutrition, physical activity, and motivation that were shared three to four times per week. Social media comments were coded using NVivo 11.0 to identify recurrent themes and subthemes., Results: 1) Social media provided accountability, emotional support, and shared behavioral strategies. 2) Motivators for lifestyle changes included family support, personal goals, and non-scale victories. 3) Challenges included negative peers, challenges with planning and tracking, and time constraints., Conclusion: Adolescents considering bariatric surgery identified social media as a tool for social support and reinforcement of strategies for successful behavior change. Important motivators and challenges to lifestyle changes were identified.- Published
- 2020
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41. Laparoscopic Sleeve Gastrectomy Carries a Lower Perioperative Mortality Including Sudden Cardiac Death over Roux-en-Y Gastric Bypass in Patients with a Prior Cardiac History: An MBSAQIP Analysis.
- Author
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Foster MW, Gershuni VM, Tewksbury CM, Giri JS, Dumon KR, Rame JE, and Williams NN
- Subjects
- Adult, Bariatric Surgery adverse effects, Bariatric Surgery mortality, Death, Sudden, Cardiac epidemiology, Death, Sudden, Cardiac etiology, Female, Gastrectomy adverse effects, Gastrectomy methods, Gastric Bypass adverse effects, Heart Diseases complications, Heart Diseases epidemiology, Humans, Laparoscopy adverse effects, Laparoscopy mortality, Male, Middle Aged, Mortality, Myocardial Infarction complications, Myocardial Infarction mortality, Myocardial Infarction surgery, Obesity, Morbid complications, Obesity, Morbid epidemiology, Patient Readmission statistics & numerical data, Percutaneous Coronary Intervention mortality, Percutaneous Coronary Intervention statistics & numerical data, Perioperative Period adverse effects, Perioperative Period statistics & numerical data, Treatment Outcome, Weight Loss, Gastrectomy mortality, Gastric Bypass mortality, Heart Diseases surgery, Obesity, Morbid mortality, Obesity, Morbid surgery, Perioperative Period mortality
- Abstract
Background: Although bariatric surgery has proven beneficial for those with cardiovascular disease (CVD), the overall and procedure-specific risk associated with bariatric surgery in this patient population remains unknown., Design: Patients who underwent primary laparoscopic, laparoscopic-assisted, or robotic-assisted Roux-En-Y gastric bypass (RYGB) or sleeve gastrectomy (SG) at a MBSAQIP-accredited center were included (n = 494,611). Exposures include history of MI, PCI, or cardiac surgery who underwent RYGB or SG. Outcome measures were 30-day mortality, perioperative cardiac arrest, and rehospitalization., Results: Of 494,611 patients enrolled in MBSAQIP, 15,923 had a history of MI, PCI, or cardiac surgery (prior cardiac history). Patient history of MI, PCI, and cardiac surgery was associated with significantly increased adjusted risk of perioperative cardiac arrest requiring CPR (OR: 2.31, 2.12, 2.42, respectively) and adjusted 30-day mortality (OR: 1.72, 1.50, 1.68, respectively). Prior cardiac history was associated with increased adjusted 30-day readmission rate (MI - OR, 1.42; PCI - OR, 1.45; and cardiac surgery - OR, 1.68). Further, 30-day postoperative readmission, postoperative cardiac arrest, and death were lower for patients undergoing SG compared to RYGB (OR: 0.48, 0.49, and 0.54 respectively)., Conclusion and Relevance: Prior cardiac history was associated with significant greater risk of perioperative cardiac arrest and 30-day mortality among patients undergoing bariatric surgery. SG was associated with less adverse events than RYGB among this population. While there is a clear benefit to weight loss in patients with CVD, it is important to consider whether cardiac patients considering bariatric surgery may require additional preoperative optimization, perioperative interventions, and postoperative monitoring.
- Published
- 2020
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42. Nationwide Analysis of 30-Day Readmissions After Esophagectomy: Causes, Costs, and Risk Factors.
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Goel NJ, Iyengar A, Kelly JJ, Mavroudis C, Lancaster C, Williams NN, Dempsey DT, and Kucharczuk J
- Subjects
- Aged, Cohort Studies, Female, Humans, Male, Middle Aged, Retrospective Studies, Risk Factors, United States, Esophagectomy, Health Care Costs, Patient Readmission economics, Patient Readmission statistics & numerical data, Postoperative Complications economics, Postoperative Complications epidemiology
- Abstract
Background: Postsurgical readmissions are an increasingly scrutinized marker of health care quality. We sought to estimate the rate, risk factors, causes, and costs associated with readmissions after esophagectomy in a large, nationally representative cohort., Methods: We studied patients from the Nationwide Readmissions Database undergoing esophagectomy from 2010 to 2014. Data were collected on the prevalence and indications for readmission within 30 days as well as the hospital-, procedure-, and patient-level risk factors as determined by multivariable logistic regression., Results: Among 13,282 cases, the rate of 30-day readmission was 19.4%, with the most common indications for readmission being pulmonary (20.6%) and gastrointestinal complications (20%). Median cost of readmission was $9660 (interquartile range, $5392 to $20,447), and pulmonary complications accounted for the greatest total cost burden at 25.8% of all readmission-related costs. Independent risk factors for readmission on multivariable analysis included perioperative blood transfusion (adjusted odds ratio [AOR] 1.33; 95% confidence interval [CI], 1.08 to 1.65; P = .008), discharge to a nursing facility (AOR 1.83; 95% CI, 1.41 to 2.39; P < .001), high illness severity based on All Patients Refined Diagnosis-Related Groups scoring (AOR 1.49; 95% CI, 1.21 to 1.84; P < .001), chronic renal failure (AOR 1.61; 95% CI, 1.13 to 2.29; P = .009), and comorbid drug abuse (AOR 2.19; 95% CI, 1.08 to 4.41; P = .029)., Conclusions: Nearly 1 in 5 patients undergoing esophagectomy are readmitted within 30 days of discharge, at a median cost of $9660 per readmission. Pulmonary complications account for the greatest number of readmissions and the greatest total cost burden. Targeting the causes of readmission, especially pulmonary causes, may help significantly reduce the total morbidity and health care costs associated with esophagectomy., (Copyright © 2020 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.)
- Published
- 2020
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43. Cutting through the fat: a retrospective analysis of clinical outcomes, cost, and quality of life with the addition of panniculectomy to ventral hernia repair in overweight patients.
- Author
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Hutchison CE, Rhemtulla IA, Mauch JT, Broach RB, Enriquez FA, Hernandez JA, Messa CA 4th, Williams NN, Harbison SP, and Fischer JP
- Subjects
- Body Mass Index, Female, Humans, Male, Middle Aged, Outcome and Process Assessment, Health Care, Postoperative Complications diagnosis, Postoperative Complications epidemiology, Retrospective Studies, United States, Abdominal Wall surgery, Abdominoplasty adverse effects, Abdominoplasty methods, Hernia, Ventral complications, Hernia, Ventral surgery, Herniorrhaphy adverse effects, Herniorrhaphy methods, Lipectomy methods, Overweight complications, Overweight diagnosis, Overweight psychology, Overweight surgery, Quality of Life
- Abstract
Background: Due to the increased prevalence of overweight patients with ventral hernia, abdominal wall reconstruction combining ventral hernia repair (VHR) with panniculectomy (VHR-PAN) in overweight patients is increasingly considered. We present a retrospective comparison between VHR-PAN and VHR alone in overweight patients by examining costs, clinical outcomes, and quality of life (QoL)., Methods: Patients with body mass index (BMI) > 25.0 kg/m
2 underwent VHR-PAN or VHR alone between September 2015 and May 2017 with a single surgeon and were matched into cohorts by BMI and age (n = 24 in each cohort). QoL was assessed using the Hernia-related Quality of Life Survey (HerQLes). Cost was assessed using billing data. Statistical analyses were performed using Fisher's exact tests, Mann-Whitney U tests, and regression modeling., Results: Hernia defect size (p = 0.127), operative time (p = 0.140), mesh placement (p = 0.357), and recurrence rates (p = 0.156) did not vary significantly between cohorts at average follow up of one year. 60% of patients completed QoL surveys, with 61% net improvement in VHR-PAN postoperatively (p = 0.042) vs 36% in VHR alone (p = 0.054). Mean total hospitalization costs were higher for VHR alone (p = 0.019). Regression modeling showed no significant independent contribution of procedure performed due to differences in cost, wound complications, or hernia recurrence., Conclusions: At mean follow up of 2 years, VHR-PAN patients reported a comparable increase in QoL to those who received VHR alone without significantly different cost and complication rates. Concurrent VHR-PAN may therefore be a safe approach for overweight patients presenting with hernia and excess abdominal skin.- Published
- 2019
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44. Prebariatric surgery care and postoperative outcomes: increased number of visits associated with smaller weight losses over first 2 postoperative years.
- Author
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Tewksbury C, Wu J, Allison KC, Gardiner H, Dumon KR, Williams NN, and Sarwer DB
- Subjects
- Adult, Female, Follow-Up Studies, Humans, Male, Middle Aged, Retrospective Studies, Time Factors, Treatment Outcome, Laparoscopy, Obesity, Morbid surgery, Preoperative Care, Weight Loss
- Abstract
Background: The prebariatric surgery assessment process can be challenging to patients and serve as a barrier to surgery. There is limited evidence to support its utility in improving postoperative outcomes for the majority of patients., Objectives: To assess the relationship between preoperative care and postoperative weight loss and follow-up in the first 2 postoperative years., Setting: University Hospital, United States., Methods: Frequency and duration of preoperative assessment and medical weight management contacts were retrospectively collected and assessed in relation to percent weight change over the first 24 months postoperatively in adults who underwent an initial bariatric surgical procedure between 2009 and 2014., Results: Patients (n = 1303) were 44.4 ± 11.9 years with a body mass index of 48 ± 8.6 kg/m
2 . The frequency of preoperative contacts (all types) and duration of preoperative care were not associated with postoperative weight loss or follow-up. A greater number of individual (one-to-one) visits with the bariatric surgery team and additional psychology visits were associated with smaller postoperative weight losses (individual = -.27%, 95% confidence interval -.47%, -.07%; P = .01; psychology = -1.46%, 95% confidence interval -2.79%, -.12%; P = .03)., Conclusions: These observations suggest the intensity and length of the preoperative assessment period is unrelated to early postoperative weight loss. Additional individual visits with the bariatric team and the psychologist before surgery were associated with smaller postoperative weight loss, suggesting that clinicians may be appropriately identifying complex patients and are making efforts to address this complexity with additional preoperative assessment and care., (Copyright © 2019 American Society for Bariatric Surgery. Published by Elsevier Inc. All rights reserved.)- Published
- 2019
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45. Bariatric surgery before and after kidney transplantation: long-term weight loss and allograft outcomes.
- Author
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Cohen JB, Lim MA, Tewksbury CM, Torres-Landa S, Trofe-Clark J, Abt PL, Williams NN, Dumon KR, and Goral S
- Subjects
- Adult, Allografts physiology, Body Mass Index, Female, Graft Survival physiology, Humans, Male, Middle Aged, Obesity, Morbid surgery, Postoperative Complications epidemiology, Retrospective Studies, Time-to-Treatment, Bariatric Surgery adverse effects, Bariatric Surgery statistics & numerical data, Kidney Transplantation adverse effects, Kidney Transplantation statistics & numerical data, Weight Loss physiology
- Abstract
Background: Severe obesity is frequently a barrier to kidney transplantation, and kidney transplant recipients often have significant weight gain following transplantation., Objectives: The goals of this study were to evaluate the long-term risks and benefits of bariatric surgery before and after kidney transplantation., Setting: University Hospital, United States., Methods: We performed a retrospective cohort study of 43 patients who had pretransplantation bariatric surgery and 21 patients who had posttransplantation bariatric surgery from 1994 to 2017 with propensity-score matching to identify matched controls using national registry data., Results: Body mass index at the time of transplantation was similar in patients who underwent bariatric surgery before versus after transplantation (32 versus 34 kg/m
2 , P = .172). There was no significant difference in body mass index in the 5 years after bariatric surgery among patients who underwent bariatric surgery before versus after kidney transplantation (36 versus 32 kg/m2 , P = 0.814). Compared with matched controls, bariatric surgery before (n = 38) and after (n = 18) kidney transplantation was associated with a decreased risk of allograft failure (hazard ratio .31 [95% confidence interval .29-0.33] and .85 [95% confidence interval .85-.86] for pre- and posttransplant, respectively) and mortality (hazard ratio .57 [95% confidence interval .53-.61] and .80 [95% confidence interval .79-.82] for pre- and posttransplant, respectively)., Conclusions: Bariatric surgery before and after kidney transplantation results in similar maintenance of weight loss and improved long-term allograft survival compared with matched controls. Bariatric surgery appears to be a safe and reasonable approach to weight loss both before and after transplantation., (Copyright © 2019 American Society for Bariatric Surgery. Published by Elsevier Inc. All rights reserved.)- Published
- 2019
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46. Health and appearance: Factors motivating the decision to seek bariatric surgery.
- Author
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Pearl RL, Wadden TA, Walton K, Allison KC, Tronieri JS, and Williams NN
- Subjects
- Adult, Cross-Sectional Studies, Female, Humans, Male, Middle Aged, Obesity epidemiology, Obesity psychology, Obesity surgery, Surveys and Questionnaires, Weight Loss, Bariatric Surgery psychology, Bariatric Surgery statistics & numerical data, Body Image psychology, Motivation
- Abstract
Background: Few studies have examined the motivating factors and people that lead patients to seek bariatric surgery. Bariatric surgery helps to improve body image, but little is known about patients' desired changes in the appearance of specific body parts., Objectives: To identify key factors and people motivating patients' decision to seek bariatric surgery, and to assess body dissatisfaction and desire for surgery to change the appearance of specific body parts., Setting: U.S. university-based hospital clinic., Methods: Patients seeking bariatric surgery (N = 208, 78.4% women, 52.4% black, mean age = 42.0 ± 12.3 yr, mean body mass index = 46.7 ± 8.5 kg/m
2 ) completed the Reasons for Bariatric Surgery questionnaire before their preoperative Psychosocial-behavioral evaluation. Participants rated (1-10) the importance of 15 potential reasons and 7 potential people motivating their decision to seek bariatric surgery. Participants also rated their dissatisfaction and desire for surgery to change the appearance of 11 body parts., Results: Mean scores of motivating factors were highest for Physical Health (9.9 ± .4), followed by Longevity (9.7 ± .9). Patients reported high body dissatisfaction and desire for surgery to change the appearance of several body parts, including stomach and thighs. "Myself" was the highest-rated motivating person, followed by healthcare providers, family, and someone who had undergone bariatric surgery., Conclusions: Health is the primary reason reported by patients for seeking bariatric surgery. Patients also report a strong desire for surgery to change the appearance of their body. Patients are self-driven to pursue surgery but are also influenced by healthcare providers, family, and people who have undergone surgery. (Surg Obes Relat Dis 2019;X:XXX-XXX.) © 2019 American Society for Metabolic and Bariatric Surgery. All rights reserved., (Copyright © 2019 American Society for Bariatric Surgery. Published by Elsevier Inc. All rights reserved.)- Published
- 2019
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47. Psychopathology, disordered eating, and impulsivity as predictors of outcomes of bariatric surgery.
- Author
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Sarwer DB, Allison KC, Wadden TA, Ashare R, Spitzer JC, McCuen-Wurst C, LaGrotte C, Williams NN, Edwards M, Tewksbury C, and Wu J
- Subjects
- Depression psychology, Humans, Obesity, Morbid surgery, Psychopathology, Risk, Substance-Related Disorders psychology, Treatment Outcome, Weight Loss, Bariatric Surgery adverse effects, Bariatric Surgery psychology, Feeding and Eating Disorders psychology, Impulsive Behavior
- Abstract
Outcomes of bariatric surgery, while frequently impressive, are not universal and vary between patients and across surgical procedures. Between 20% and 30% of patients experience suboptimal weight loss or significant weight regain within the first few postoperative years. The reasons for this are not fully understood, but likely involve both physiologic processes, behavioral factors, and psychological characteristics. Evidence suggests that preoperative psychosocial status and functioning can contribute to suboptimal weight losses and/or postoperative psychosocial distress. Much of this work has focused on the presence of recognized psychiatric diagnoses and with particular emphasis on mood disorders as well as binge eating disorder. Several studies have suggested that the presence of preoperative psychopathology is associated with suboptimal weight losses, postoperative complications, and less positive psychosocial outcomes. Contemporary psychological theory suggests that it may be shared features across diagnoses, rather than a discrete diagnosis, that better characterizes psychopathology. Mood and substance use disorders as well as binge eating disorder, share common features of impulsivity, although clinicians and researchers often use complementary, yet different terms, such as emotional dysregulation or disinhibition (i.e., loss of control over eating, as applied to food intake), to describe the phenomenon. Impulse control is a central factor in eating behavior and extreme obesity. It also may contribute to the experience of suboptimal outcomes after bariatric surgery, including smaller than expected weight loss and psychosocial distress. This paper reviews the literature in these areas of research and articulates a direction for future studies of these complex relationships among persons with extreme obesity., (Copyright © 2019 American Society for Bariatric Surgery. Published by Elsevier Inc. All rights reserved.)
- Published
- 2019
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48. National Postoperative Bariatric Surgery Outcomes in Patients with Chronic Kidney Disease and End-Stage Kidney Disease.
- Author
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Cohen JB, Tewksbury CM, Torres Landa S, Williams NN, and Dumon KR
- Subjects
- Adult, Bariatric Surgery statistics & numerical data, Female, Humans, Kidney Failure, Chronic epidemiology, Male, Middle Aged, Registries statistics & numerical data, Retrospective Studies, Risk Factors, United States epidemiology, Bariatric Surgery adverse effects, Obesity epidemiology, Obesity surgery, Renal Insufficiency, Chronic epidemiology
- Abstract
Purpose: Obesity is a major risk factor for end-stage kidney disease (ESKD) and is often a barrier to kidney transplantation. However, limited evidence exists evaluating postoperative bariatric surgery outcomes in patients with chronic kidney disease (CKD) and ESKD., Materials and Methods: We performed a retrospective cohort study of patients who underwent bariatric surgery in 2015-2016 using the national Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program dataset. Propensity score matching was used to balance characteristics across patients with CKD and ESKD vs. those without CKD., Results: There were 323,034 patients without CKD, 1694 patients with CKD, and 925 patients with ESKD who underwent bariatric surgery. Patients with CKD and ESKD had a significantly increased risk of 30-day reoperation (CKD odds ratio [OR] 2.25 95% confidence interval [CI] 1.45-3.51; ESKD OR 3.10, 95% CI 1.72-5.61) and readmission (CKD OR 1.98, 95% CI 1.53-2.56; ESKD OR 2.97, 95% CI 2.05-4.31) compared to patients without CKD; mortality risk was elevated in patients with ESKD (OR 11.59, 95% CI 6.71-20.04) but not in those with CKD (OR 1.00, 95% CI 0.32-3.11). Rates of adverse outcomes were < 15% across all groups. There were 12, 50, and 172 deaths per 1000 person-years among patients without CKD, with CKD, and with ESKD, respectively., Conclusion: Patients with CKD and ESKD experienced higher risk of postbariatric surgery complications compared to those without kidney disease, although absolute complication rates were low across all groups. CKD and ESKD should not be perceived as contraindications to bariatric surgery.
- Published
- 2019
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49. Interprofessional Simulations to Inform Perioperative Facility Planning and Design.
- Author
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Torres-Landa S, Neylan C, Quinlan K, Klock C, Jefferson C, Williams NN, Caskey RC, Greulich S, Kolb G, Morgan C, Mahoney K, and Dumon KR
- Subjects
- Hospital Design and Construction, Hospital Planning, Operating Rooms, Personnel, Hospital
- Abstract
Objective: The purpose of this study is to report our experience with interprofessional simulations, executed in a mock-up of a proposed perioperative space, that were designed to elicit valuable end-user feedback on the design of the perioperative space., Design: A styrofoam, life-sized model of a perioperative unit was constructed. Various medical professionals and support staff participated in interactive sessions, including workflow simulations, and provided feedback on the perioperative design. Based on participant feedback, the perioperative design was modified, and the styrofoam model was re-constructed. A second round of sessions was conducted, and the change in participant feedback was analyzed., Setting: This study took place under the auspices of the University of Pennsylvania in Philadelphia, Pennsylvania, within Penn Medicine., Participants: One-hundred and ninety-three medical professionals and front line operating room staff participated in the initial round of interactive sessions, and 134 participated in the second round (after re-construction)., Results: In the first round of simulations and interactive sessions, participants spent 560 hours engaging with the space. Modifications were then made to the perioperative design based on participant feedback, and a second round was conducted, in which participants spent 403 hours in the space. Floor plans for round 2 show significant changes compared with round 1, and mean design satisfaction scores for round 2 (3.78 ± 0.41) were significantly higher than for round 1 (3.61 ± 0.49) (p = 0.02). The quality of feedback was associated with the type of interactive session the user participated in., Conclusions: This study suggests that simulations and other interactive sessions, when executed in a mock-up of a proposed perioperative space, can elicit valuable end-user feedback that impacts the final design of the perioperative space and that would traditionally be difficult to obtain until after construction and move-in., (Copyright © 2018 Association of Program Directors in Surgery. All rights reserved.)
- Published
- 2019
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50. The Malnourished Patient With Obesity: A Unique Paradox in Bariatric Surgery.
- Author
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Fieber JH, Sharoky CE, Wirtalla C, Williams NN, Dempsey DT, and Kelz RR
- Subjects
- Adult, Female, Humans, Hypoalbuminemia complications, Male, Middle Aged, Morbidity, Bariatric Surgery adverse effects, Malnutrition etiology, Obesity surgery, Postoperative Complications etiology
- Abstract
Background: Hypoalbuminemia is a known risk factor for poor outcomes following surgery. Obesity can be associated with modest to severe malnutrition. We evaluated the impact of hypoalbuminemia on surgical outcomes in patients with obesity undergoing elective bariatric surgical procedures., Materials and Methods: The 2015 metabolic and bariatric surgery accreditation and quality improvement program database was queried. Patients ≥ 18 y with body mass index ≥35 undergoing bariatric surgery were included. Revision procedures were excluded. Patients were classified by albumin level (albumin ≥3.5 g/dL [normal], 3.49-3.0 g/dL [mild], 2.99-2.5 g/dL [moderate], and <2.5 g/dL [severe]). Independent logistic regression models were developed to estimate the adjusted odds of (1) death or serious morbidity (DSM); (2) mild to moderate complications; (3) severe complications; and (4) 30-d readmissions by albumin level. In addition, effect modification by >10% weight loss was examined., Results: A total of 106,577 patients were included in the study. Over 6% of patients had hypoalbuminemia. Fifty-five percent of complications were severe as categorized by the Clavien-Dindo classification. Patients with mild hypoalbuminemia had 20% increased odds of DSM (95% confidence interval: 1.1-1.4). There was increasing likelihood of DSM with severe hypoalbuminemia. Patients with mild hypoalbuminemia had 20% increased odds of 30-d readmission (confidence interval: 1.1-1.3). A >10% weight loss modified the effect of moderate to severe hypoalbuminemia on DSM., Conclusions: More than 6% of patients with obesity undergoing bariatric surgery are malnourished. Hypoalbuminemia is an important and modifiable risk factor for postoperative adverse outcomes following bariatric surgery. Preoperative weight loss >10% combined with moderate to severe hypoalbuminemia is synergistic for high rates of DSM and should be addressed before proceeding with bariatric surgery., (Copyright © 2018 Elsevier Inc. All rights reserved.)
- Published
- 2018
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