27 results on '"Williams, Patrick D."'
Search Results
2. Drug Induced Maculopathies
- Author
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Williams, Patrick D., primary and McClellan, Andrew, additional
- Published
- 2021
- Full Text
- View/download PDF
3. Drug Induced Maculopathies
- Author
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Williams, Patrick D., primary and McClellan, Andrew, additional
- Published
- 2020
- Full Text
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4. Advancements in Microbial Polysaccharide Research for Frozen Foods and Microencapsulation of Probiotics
- Author
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Soma, Pavan Kumar, Williams, Patrick D., Moon, BoKyung, Lo, Y. Martin, Barbosa-Cánovas, Gustavo, Series editor, Yanniotis, Stavros, editor, Taoukis, Petros, editor, Stoforos, Nikolaos G., editor, and Karathanos, Vaios T., editor
- Published
- 2013
- Full Text
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5. Advancements in non-starch polysaccharides research for frozen foods and microencapsulation of probiotics
- Author
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Soma, Pavan Kumar, Williams, Patrick D., and Lo, Y. Martin
- Published
- 2009
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6. Effects of Ultraviolet Radiation on the Gram-Positive Marine Bacterium Microbacterium maritypicum
- Author
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Williams, Patrick D., Eichstadt, Shaundra L., Kokjohn, Tyler A., and Martin, Eugene L.
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- 2007
- Full Text
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7. Serous Detachment of the Neural Retina
- Author
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Anand, Rajiv, primary and Williams, Patrick D., additional
- Published
- 2009
- Full Text
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8. List of Contributors
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Ahmed, Iqbal ike K., primary, Ahmed, Irma, additional, Ai, Everett, additional, Al-Ghoul, Ahmed, additional, Allen, David, additional, Alvi, Nishat P., additional, Anand, Rajiv, additional, Ang, Leonard P.-K., additional, Apple, David J., additional, Archer, Desmond B., additional, Arnold, Anthony C., additional, Arshinoff, Steve A., additional, Assil, Kerry K., additional, Atebara, Neal H., additional, Atluri, Harvinder K.S., additional, Augsburger, James J., additional, Aylward, G. William, additional, Azar, Dimitri T., additional, Baker, Brad J., additional, Balcer, Laura Joan, additional, Barnett, C.J., additional, Baumal, Caroline R., additional, Bearelly, Srilaxmi, additional, Benson, William E., additional, Berger, Steven Thomas, additional, Biswas, Jyotirmav, additional, Bolling, James P., additional, Bornfeld, Norbert, additional, Bose, Swaraj, additional, Bouchard, Charles S., additional, Boulton, Michael E., additional, Brandt, James D., additional, Brodsky, Michael C., additional, Brown, Kimberly Ellen, additional, Brown, Gary C., additional, Brown, Melissa M., additional, Budenz, Donald L., additional, Bui, Alex, additional, Burns, Stephen K., additional, Campolattaro, Brian N., additional, Cantor, Louis B., additional, Jr, Antonio Capone, additional, Carter, Keith D., additional, Chan, Chi-Chao, additional, Chang, Stanley, additional, Chao, Jennifer R., additional, Charonis, George C., additional, Chew, Paul T.K., additional, Ciardella, Antonio P., additional, Civan, Mortimer M., additional, Clark, Abbott F., additional, Clarke, Jonathan, additional, Contreras, Janice E., additional, Collin, J. Richard O., additional, Codère, François, additional, Corrêa, Zélia M., additional, Cowan, Claude L., additional, Craven, E. Randy, additional, Cruess, Alan F., additional, Custer, Phillip L., additional, Dahan, Elie, additional, Dai, Eric, additional, Damato, Bertil E., additional, Damji, Karim F., additional, Davidson, Richard S., additional, Davis, Elizabeth A., additional, Dhaliwal, Deepinder K., additional, Diamond, Gary R., additional, Do, Diana V., additional, Donahue, Sean P., additional, Dortzbach, Richard K., additional, Drenser, Kimberly A., additional, Duker, Jay S., additional, Dutton, Jonathan J., additional, Edgington, Bryan, additional, Eggers, Howard M., additional, Ehlers, William, additional, Engelbert, Michael, additional, Espandar, Ladan, additional, Evans, Monica, additional, Farjo, Ayad A., additional, Farjo, Qais Anastas, additional, Faucett, Donald C., additional, Feiz, Vahid, additional, Fine, I. Howard, additional, Fisher, Yale L., additional, Fishman, Gerald A., additional, Forster, David J., additional, Fox, Gregory M., additional, Freedman, Jeffrey, additional, Friedman, David S., additional, Friedman, Neil J., additional, Friedman, Deborah I., additional, Fu, Arthur D., additional, Fynn-Thompson, Nicoletta, additional, Ganatra, Jyotsom, additional, Gayre, Gregg S., additional, Gery, Igal, additional, Ghanem, Ramon C., additional, Giblin, Michael, additional, Gigantelli, James W., additional, Goldberg, Anna, additional, Goldberg, Robert A., additional, Goldberg, William, additional, Goldberg, Ivan, additional, Goldstein, Debra A., additional, Goldstein, Michael H., additional, Gonder, John R., additional, Green, Jeffrey P., additional, Greven, Craig M., additional, Gross, Nicole E., additional, Gross, Ronald L., additional, Grover, Sandeep, additional, Guercio, Jason R., additional, Gupta, Vishali, additional, Gupta, Amod, additional, Gurkan, Sevgi, additional, Guthoff, Rudolf E., additional, Hallak, Joelle, additional, Haller, Julia A., additional, Hamilton, Richard S., additional, Harbour, J. William, additional, Hardten, David R., additional, Harris, Alon, additional, Hedges Jr, Thomas R., additional, Heier, Jeffrey S., additional, Henderson, Polly A., additional, Herndon, Leon W., additional, Hitchings, Roger A., additional, Ho, Allen C., additional, Hoffman, Richard S., additional, Holz, Huck A., additional, Howard, Gene R., additional, Howes, Frank W., additional, Hsu, Jason, additional, Hurwitz, Jeffrey J., additional, Inomata, Hajime, additional, Ip, Michael, additional, Isaacs, Robert T., additional, Izak, Andrea M., additional, Jampel, Henry, additional, Jampol, Lee M., additional, Jiyamapa, Julia, additional, Johnson, Chris A., additional, Johnson, T. Mark, additional, Johnson, Mark W., additional, Jones, Nicholas, additional, Kahook, Malik, additional, Kanner, Elliott M., additional, Kapusta, Michael A., additional, Kardon, Randy, additional, Karp, Carol L., additional, Kass, Michael, additional, Katz, L. Jay, additional, Kaufman, Paul L., additional, Khan, Baseer, additional, Khaw, Peng Tee, additional, Kim, Gene, additional, Kimura, Alan E., additional, Kitzmann, Anna, additional, Klancnik, James M., additional, Koch, Douglas D., additional, Kohnen, Thomas, additional, Kojima, Takashi, additional, Kornmehl, Ernest W., additional, Kramarevsky, Natalia, additional, Labbe, Thad, additional, Lane, Stephen S., additional, Lavin, Patrick J.M., additional, Lawton, Andrew, additional, Lee, Paul P., additional, Leen, Martha Motuz, additional, Levinson, Ralph, additional, Lim, Ridia, additional, Lingua, Robert W., additional, Lipham, William J., additional, Lopez, Pedro F., additional, Lundstrom, Mats, additional, Magnante, Peter, additional, Mandava, Naresh, additional, Marak, George E., additional, Marmor, Michael F., additional, Marten, Lisa, additional, Mathura, Jeevan R., additional, Martidis, Adam, additional, Mattox, Cynthia, additional, McDermott, Mark L., additional, McLeod, Stephen D., additional, Mejico, Luis J., additional, Meyers, Sanford M., additional, Mieler, William F., additional, Migdal, Clive S., additional, Miller, David, additional, Miller, Russell, additional, Mimura, Tatsuya, additional, Mittra, Robert A., additional, Moorthy, Ramana S., additional, Morley, Michael G., additional, Morse, Lawrence S., additional, Moshirfar, Majid, additional, Moster, Mark L., additional, Nehls Rikkers, Sarah M., additional, Neff, Ann G., additional, Newlin, Anna C., additional, Noble, Kenneth G., additional, Noecker, Robert J., additional, Okada, Annabelle A., additional, Olson, Jeffrey L., additional, Opalinski, Yvonne A.V., additional, Packer, Mark, additional, Pandey, Suresh K., additional, Patel, Vivek Ravindra, additional, Pavesio, Carlos E., additional, Pineles, Stacy, additional, Piva, Alfio, additional, Piltz-Seymour, Jody, additional, Pollack, John S., additional, Prall, F. Ryan, additional, Price, Marianne O., additional, Price, Francis W., additional, Primack, Jonathan D., additional, Pruett, Ronald C., additional, Puliafito, Carmen A., additional, Pulido, Jose S., additional, Quiros, Peter A., additional, Ramulu, Pradeep, additional, Ramos-Esteban, Jerome C., additional, Rao, P. Kumar, additional, Rao, Narsing A., additional, Read, Russell W., additional, Rechtman, Ehud, additional, Regillo, Carl D., additional, Reichel, Elias, additional, Rhee, Douglas J., additional, Rhee, Steven S., additional, Rheinstrom, Stephen D., additional, Riedel, Patrick J., additional, Rikkers, Sarah M., additional, Robinson, Fiona O., additional, Rodriguez-Coleman, Hannah, additional, Rogers, Adam, additional, Roe, Richard, additional, Roh, Shiyoung, additional, Rosen, Emanuel S., additional, Rosenblatt, Brett, additional, Rosenfeld, Philip J., additional, Rubenstein, Jonathan B., additional, Rubin, Steven E., additional, Rubin, Richard M., additional, Rubsamen, Patrick E., additional, Saadati, Hossein G., additional, Sadun, Alfredo A., additional, Salim, Sarwat, additional, Salinas, Humberto, additional, Samuelson, Thomas W., additional, Sanborn, George E., additional, Sarmiento, Jerome S., additional, Scheufele Cleary, Tina A., additional, Schor, Paulo, additional, Schubert, Hermann D., additional, Schuman, Joel, additional, Schwab, Ivan R., additional, Schwartz, Gary S., additional, Scott, Clifford A., additional, Sebag, Jerry, additional, See, Jovina L.S., additional, Selkin, Robert P., additional, Shields, Bruce, additional, Shingleton, Bradford, additional, Sierra, Patricia B., additional, Sieving, Paul A., additional, Sivalingam, Arunan, additional, Small, Kent W., additional, Smiddy, William E., additional, Soong, Kaz, additional, Soukiasian, Sarkis, additional, Spaide, Richard F., additional, Spoor, Thomas C., additional, Stasi, Kalliopi, additional, Steel, David, additional, Stein, Joshua D., additional, Steinemann, Thomas L., additional, Suchecki, Jeanine, additional, Sugar, Joel, additional, Sugar, Alan, additional, Tan, J.C.H., additional, Tanenbaum, Myron, additional, Taravella, Michael J., additional, Tasman, William S., additional, Telander, David G., additional, Tennant, Matthew T.S., additional, Tessler, Howard H., additional, Thall, Edmond H., additional, Tingey, David P., additional, Tobaigy, Faisal M., additional, Truong, Steven, additional, Tsai, James C., additional, Tsai, Julie, additional, Tsiaras, William G., additional, Tu, Elmer Y., additional, Tucker, Nancy, additional, Tuli, Sonal S., additional, Valluri, Shailaja, additional, Vander, James F., additional, Vaughn, Gregory J., additional, Virasch, Vanee Val, additional, Wadia, Hormuz P., additional, Walker, Rebecca S., additional, Walton, David Sellers, additional, Wang, Li, additional, Wang, Frederick M., additional, Wang, Ming X., additional, Wang, Robert C., additional, Wax, Martin, additional, Weinberg, David V., additional, Weinstein, Joel M., additional, Weiter, John J., additional, Werner, Liliana, additional, Wevill, Mark T., additional, White, Paul F., additional, Wiggs, Janey L., additional, Wilkinson, Charles P., additional, Williams, Patrick D., additional, Williams, George A., additional, Wirostko, William J., additional, Wollstein, Gadi, additional, Yee, Robert D., additional, Young, Joshua A., additional, and Zamir, Ehud, additional
- Published
- 2009
- Full Text
- View/download PDF
9. Retinal Toxicity of Systemic Medications
- Author
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Williams, Patrick D., primary and Callanan, David, additional
- Published
- 2008
- Full Text
- View/download PDF
10. List of Contributors
- Author
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Abad, Juan-Carlos, primary, Abelson, Mark B, additional, Abramson, David H, additional, Acquadro, Martin A, additional, Adamis, Anthony P, additional, Adams, Wesley H, additional, Afshari, Natalie A, additional, Ai, Everett, additional, Aiello, Lloyd M, additional, Aiello, Lloyd P, additional, Akduman, Levent, additional, Albano, Marissa L, additional, Albert, Daniel M., additional, Alexandrou, Terry J, additional, Alfonso, Eduardo C, additional, Alié, Jorge L, additional, Alizadeh, Hassan, additional, Al Jadaan, Ibrahim A, additional, Al-Jastaneiah, Sabah, additional, Allen, Calliope E, additional, Allen, David, additional, Allen, Robert C, additional, Alm, Albert, additional, Al-Swailem, Samar, additional, Alt, Abigail K, additional, Altaweel, Michael M, additional, Anderson, Russell, additional, Andreoli, Christopher M, additional, Androudi, Sofia, additional, Ang, Leonard PK, additional, Anzaar, Fahd, additional, Apple, David J, additional, Arrigg, Claudia A, additional, Artal, Pablo, additional, Asbell, Penny, additional, Asdourian, George K, additional, Atebara, Neal, additional, Atmaca-Sonmez, Pelin, additional, Audo, Isabelle, additional, Auffarth, Gerd U, additional, Avery, Robin K, additional, Azar, Dimitri T, additional, Baker, Ann S, additional, Balles, Mark, additional, Barnes, Scott D, additional, Barnett, Donald M, additional, Barney, Neal P, additional, Barouch, Fina C, additional, Bartley, George B, additional, Barton, Jason JS, additional, Behlau, Irmgard, additional, Belda, Jose I, additional, Bennett, Jeffrey L, additional, Bennett, Timothy J, additional, Berdy, Gregg J, additional, Bernardino, Carlo Roberto, additional, Bernardino, Vitaliano, additional, Berson, Eliot L, additional, Bharadwaj, Amitabh, additional, Bhisitkul, Robert, additional, Bhui, Ravinder D, additional, Bilyk, Jurij, additional, Biousse, Valérie, additional, Bird, Alan C, additional, Blair, Norman Paul, additional, Blodi, Barbara A, additional, Blumenkranz, Mark S, additional, Boldt, H Culver, additional, Borchert, Mark S, additional, Borrillo, Luigi, additional, Borodic, Gary E, additional, Boruchoff, S Arthur, additional, Bose, Swaraj, additional, Boulton, Michael E, additional, Bowman, RW, additional, Bradley, Elizabeth A, additional, Brazitikos, Periklis D, additional, Breeze, Robert, additional, Bressler, Neil M, additional, Bressler, Susan B, additional, Brini, Alfred, additional, Budenz, Donald L, additional, Buffenn, Angela N, additional, Burk, Scott E, additional, Butrus, Salim, additional, Callanan, David, additional, Cameron, J Douglas, additional, Cantor, Louis B, additional, Cantore, William A, additional, Cantu-Dibildox, Jorge, additional, Casas, Victoria, additional, Casper, Miriam, additional, Casten, Robin J, additional, Catoira, Yara P, additional, Cavallerano, Jerry, additional, Chai, Samantha J, additional, Chalita, Maria R, additional, Chamberlain, Sherman M, additional, Chan, Audrey S, additional, Chan, Chi-Chao, additional, Chan, Paul, additional, Chapin, Matthew J, additional, Chapman, Karen L, additional, Chen, Eric, additional, Chen, Joe, additional, Chen, Julie A, additional, Chen, Teresa C, additional, Chen, Zhou, additional, Chévez-Barrios, Patricia, additional, Chew, Emily Y, additional, Chiang, Mark, additional, Chodosh, James, additional, Chong, Eva-Marie, additional, Chun, Denise, additional, Chylack, Leo T, additional, Ciardella, Antonio P, additional, Civan, Mortimer, additional, Clamen, Liane, additional, Clark, John I, additional, Cockerham, Glenn, additional, Cohen, Andre, additional, Cohen, Elisabeth J, additional, Colby, Kathryn A, additional, Coleman, Anne L, additional, Coleman, Hanna R, additional, Colin, Joseph, additional, Collier, J Michael, additional, Comer, Grant M, additional, Conlon, M Ronan, additional, Cooper, Kim E, additional, Corbett, James J, additional, Coma, Miguel C, additional, Cyrlin, Marshall N, additional, Dagi, Linda R, additional, Dahlgren, Matthew A, additional, Daley, Timothy J, additional, Da Mata, Andrea P, additional, Damato, Bertil, additional, D'Amico, Donald J, additional, Dana, Reza, additional, Danan-Husson, Aude, additional, Danesh-Meyer, Helen B, additional, Danis, Ronald P, additional, Darlington, Jason K, additional, Davidson, Stefanie L, additional, Davis, Janet L, additional, Davis, Elizabeth A, additional, de la Cruz, Jose J, additional, de la Garza, Adam G, additional, DeAngelis, Margaret M, additional, DeMartelaere, Sheri L, additional, Demer, Joseph L, additional, Dhaliwal, Avninder, additional, Dieckert, J Paul, additional, Do, Diana V, additional, Doane, Marshall G, additional, Dodds, Christopher, additional, Dohlman, Claes H, additional, Donati, Guy, additional, Donnenfeld, Eric D, additional, Drack, Arlene, additional, Dryja, Thaddeus P, additional, Dueker, David, additional, Duker, Jay S, additional, Dunbar, Jennifer A, additional, Dunn, James P, additional, Dupps, William J, additional, Durand, Marlene L, additional, Dutton, Jonathan J, additional, Eandi, Chiara M, additional, Edward, Deepak P, additional, Egan, Robert A, additional, Eichenbaum, David A, additional, Eklund, Susan E, additional, Engle, Elizabeth C, additional, Erickson, Kristine, additional, Esmaeli, Bita, additional, Fay, Aaron, additional, Feiner, Leonard, additional, Fekrat, Sharon, additional, Ferris, Frederick L, additional, Fine, Howard F, additional, Fletcher, Donald C, additional, Flikier, Paul, additional, Floyd, Richard P, additional, Flynn, Harry W, additional, Fong, Donald S, additional, Font, Ramon L, additional, Forbes, Brian JR, additional, Foroozan, Rod, additional, Foster, Bradley S, additional, Foster, C Stephen, additional, Foster, Jill A, additional, Foulks, Gary N, additional, Fountain, Tamara R, additional, Fox, Gregory M, additional, Freddo, Thomas F, additional, Freedman, Sharon F, additional, Freund, K Bailey, additional, Friberg, Thomas R, additional, Friedman, Alan H, additional, Friedman, David, additional, Friedman, Deborah I, additional, Friedman, Ephraim, additional, Fu, Arthur D, additional, Fulton, Anne B, additional, Galal, Ahmed, additional, Galetta, Steven, additional, Gallardo, Mark, additional, Gallie, Brenda, additional, Garner, Alec, additional, Garrity, James A, additional, Gatinel, Damien, additional, Gedde, Steven J, additional, Geist, Craig E, additional, Gerber, Steve, additional, Ghanem, Ramon C, additional, Gieser, Jon P, additional, Gilmore, Michael S, additional, Gimbel, Howard V, additional, Gipson, Ilene K, additional, Glover, Tyrone, additional, Goldberg, Robert A, additional, Goldenfeld, Mordechai, additional, Goldstein, Scott M, additional, Gomi, Cintia F, additional, Gong, Haiyan, additional, Gonzales, John A, additional, Goosey, John, additional, Gottlieb, Justin L, additional, Gould, Joshua, additional, Gragoudas, Evangelos S, additional, Granet, David B, additional, Greaney, Michael J, additional, Green, Daniel G, additional, Grehn, Franz, additional, Greiner, Jack V, additional, Greven, Craig M, additional, Griepentrog, Gregory J, additional, Groenewald, Carl, additional, Grosskreutz, Cynthia L, additional, Grover, Lori Latowski, additional, Gullapalli, Vamsi K, additional, Gulur, Padma, additional, Gunther, Jonathan, additional, Gupta, Manish, additional, Gupta, Mayank, additional, Guyer, David R, additional, Haivala, Darin R, additional, Haller, Julia A, additional, Halmagyi, GM, additional, Halperin, Lawrence S, additional, Hamdi, Islam M, additional, Hamilton, Steven R, additional, Hammersmith, Kristin M, additional, Han, Dennis P, additional, Hansen, Ronald M, additional, Harbour, J William, additional, Hariprasad, Seenu M, additional, Harissi-Dagher, Mona, additional, Hassan, Shirin E., additional, Hatton, Mark P, additional, Hawley, Pamela, additional, Hayashida, Yasutaka, additional, Heckenlively, John R, additional, Hedges, Thomas R, additional, Heggie, Alfred D, additional, Heher, Katrinka L, additional, Heier, Jeffrey S, additional, Hejtmancik, J Fielding, additional, Henderson, Bonnie A, additional, Hersh, Peter S, additional, Hidayat, Ahmed A, additional, Higginbotham, Eva Juliet, additional, Hirose, Tatsuo, additional, Ho, Allen C, additional, Ho, ThucAnh T, additional, Hogan, R Nick, additional, Holck, David E, additional, Holekamp, Nancy M, additional, Hovland, Peter G, additional, Hsu, Thomas C, additional, Hsu, William C, additional, Huang, Andrew JW, additional, Hughes, Mark S, additional, Hui, Jennifer, additional, Hunter, David G, additional, Huryn, Laryssa A, additional, Husain, Deeba, additional, Hyndiuk, Robert A, additional, Ip, Michael, additional, Jacobs, Brian J, additional, Jakobiec, Frederick A, additional, Jampol, Lee M, additional, Jensen, Harold G, additional, Ji, Fei, additional, Johnson, David L, additional, Johnson, Douglas H, additional, Johnson, Mark W, additional, Johnson, R Paul, additional, Johnson, Robert N, additional, Joos, Karen M, additional, Joyce, Nancy C, additional, Jumper, J Michael, additional, Jurkunas, Ula V., additional, Kahana, Alon, additional, Kahook, Malik Y, additional, Kanner, Elliott, additional, Kalwerisky, Kevin, additional, Kaplan, Henry J, additional, Karatza, Ekaterini C, additional, Kardon, Randy, additional, Katowitz, James A, additional, Katowitz, William R, additional, Kazlas, Melanie, additional, Keefe, Kelly S, additional, Kelley, Lara, additional, Kent, Charles J, additional, Kenyon, Kenneth R, additional, Khan, Bilal F, additional, Khan, Jemshed A, additional, Khan, Naheed W, additional, Khaw, Peng Tee, additional, Kherani, Femida, additional, Kim, Eva C, additional, Kim, Hee Joon, additional, Kim, Ivana K, additional, Kim, Jonathan W, additional, Kim, Rosa Y, additional, Kim, Stella K, additional, Kim, Tae-Im, additional, Klais, Christina M, additional, Klapper, Stephen R, additional, Klein, Barbara EK, additional, Kleinmann, Guy, additional, Klink, Thomas, additional, Klisovic, Dino D, additional, Klyce, Stephen D, additional, Kocaturk, Tolga, additional, Kohnen, Thomas, additional, Kojima, Takeshi, additional, Koller, Tobias, additional, Kostick, David A, additional, Kraut, Joel A, additional, Krishnan, Chandrasekharan, additional, Krueger, Ronald R, additional, Krug, Joseph H, additional, Krupsky, Sara, additional, Kuchtey, Rachel W, additional, Kurban, Ramsay S, additional, Kurz, Paul A, additional, Kuszak, JR, additional, Kwon, Young H, additional, Labbe, Thad A, additional, Lam, Deborah L, additional, Lamkin, Jeffrey C, additional, Lamping, Kathleen A, additional, Lane, Anne Marie, additional, Lane, Katherine A, additional, Lane, Keith J, additional, Lass, Jonathan H, additional, Lawrence, Mary G, additional, Lee, Andrew G, additional, Lee, Carol M, additional, Lee, Michael S, additional, Lee, Paul P, additional, Lee, William B, additional, Leibovitch, Igal, additional, Lemke, Bradley N, additional, Lemley, Craig A, additional, Leonardi, Andrea, additional, Lessell, Simmons, additional, Levin, Leonard A, additional, Levy-Clarke, Grace A, additional, Lew, Julie C, additional, Lewis, Craig, additional, Li, Wei, additional, Lim, Laurence S, additional, Lim, Lyndell L, additional, Lim, Wee-Kiak, additional, Liu, Grant T, additional, Loewenstein, John I, additional, Lott, McGregor N, additional, Lowry, Jonathan C, additional, Lyon, David B, additional, Lytle, Robert E, additional, MacCumber, Mathew, additional, Mackool, Bonnie T, additional, Madiwale, Nalini A, additional, Mah, Francis, additional, Mainster, Martin A, additional, Manning, Michael H, additional, Mansberger, Steven L, additional, Marc, Robert E, additional, Marchong, Mellone, additional, Marcus, Dennis M, additional, Mares, Julie A, additional, Marr, Brian P, additional, Martinez, Carlos E, additional, Massof, Robert W, additional, Matsumoto, Yukihiro, additional, Mattox, Cynthia, additional, Maus, Marlon, additional, McCabe, Cathleen M, additional, McCormick, Steven A, additional, McCrakken, Michael, additional, McCulley, James P, additional, McDermott, John A, additional, McDonald, H Richard, additional, McDonald, Marguerite B, additional, McDonnell, Peter J, additional, McGillivray, Robert, additional, McKeown, Craig A, additional, McLaughlin, James, additional, McMullen, W Wynn, additional, Melamed, Shlomo, additional, Meligonis, George, additional, Mendrinos, Efstratios, additional, Meyer, Dale R, additional, Meyerle, Catherine B, additional, Mieler, William F, additional, Migliori, Michael, additional, Mihm, Martin C, additional, Miller, Darlene, additional, Miller, David, additional, Miller, Joan W, additional, Miller, Neil R, additional, Mills, David M, additional, Mills, Monte D, additional, Milman, Tatyana, additional, Mogk, Lylas, additional, Mogk, Marja, additional, Monés, Jordi, additional, Montes-Micó, Robert, additional, Morse, Christie L, additional, Morton, Asa D, additional, Moskowitz, Anne, additional, Mukai, Shizuo, additional, Murphree, A Linn, additional, Murphy, Robert P, additional, Murray, Timothy G, additional, Murray, Philip I, additional, Nagao, Karina, additional, Neitz, Jay, additional, Neitz, Maureen, additional, Netland, Peter A, additional, Neufeld, Arthur H, additional, Newman, Nancy J, additional, Ng, Eugene WM, additional, Nguyen, Quan Dong, additional, Niederkorn, Jerry Y, additional, Noecker, Robert J, additional, Nussenblatt, Robert B, additional, O'Brien, Joan M, additional, O'Brien, Paul D, additional, O'Brien, Terrence P, additional, O'Day, Denis, additional, Olk, R Joseph, additional, Olsen, Karl R, additional, Onal, Sumru, additional, Ooi, Yen Hoong, additional, Opremcak, E Mitchel, additional, Ousler, George, additional, Ozment, Randall R, additional, Packer, Samuel, additional, Palmer, Millicent L, additional, Papaliodis, George N, additional, Park, DJ John, additional, Parke, David W, additional, Parsa, Cameron F, additional, Parsons, M Andrew, additional, Pasquale, Louis R, additional, Patel, Neha N, additional, Patel, Sayjal J, additional, Patrianakos, Thomas D, additional, Patrinely, James R, additional, Pavan-Langston, Deborah, additional, Peli, Eli, additional, Pepin, Susan M, additional, Perez, Victor L, additional, Pérez-Santonja, Juan J, additional, Perfect, John R, additional, Perry, Henry D, additional, Piatigorsky, Joram, additional, Pieramici, Dante, additional, Pierce, Eric A, additional, Pineda, Roberto, additional, Pless, Misha L, additional, Pomeranz, Howard D, additional, Pournaras, Constantin J, additional, Power, William, additional, Prakash, Manvi, additional, Prasad, Anita G, additional, Purvin, Valerie, additional, Quillen, David A, additional, Quinn, Graham E, additional, Rabena, Melvin D, additional, Rae, James L, additional, Raizman, Michael B, additional, Randazzo, Alessandro, additional, Rao, Narsing A, additional, Rapuano, Christopher J, additional, Reeves, Sherman W, additional, Regillo, Carl D, additional, Reichel, Elias, additional, Reinke, Martin H, additional, Rhee, Douglas, additional, Richter, Claudia U, additional, Rizzo, Joseph F, additional, Robb, Richard M, additional, Roden, Anja C, additional, Rodgers, I Rand, additional, Rodrigues, Merlyn M, additional, Ron, Yonina, additional, Rose, Geoffrey E, additional, Rosen, Emanuel S, additional, Rosenbaum, James T, additional, Rosenthal, Perry, additional, Rouse, Strutha C, additional, Rovner, Barry W, additional, Rozanowska, Malgorzata, additional, Rubin, Michael P, additional, Rubin, Peter AD, additional, Rumelt, Shimon, additional, Rustgi, Anil K, additional, Rutar, Tina, additional, Ruttum, Mark S, additional, Rutzen, Allan R, additional, Ryan, Edward T, additional, Sadun, Alfredo A, additional, Sahel, José-Alain, additional, Saligan, Leorey, additional, Salim, Sarwat, additional, Salmon, John F, additional, Salomão, Diva R, additional, Sami, David, additional, Sandberg, Michael A, additional, Sangwan, Virender S, additional, Saornil, Maria A, additional, Sassani, Joseph W, additional, Sayegh, Rony R, additional, Schachat, Andrew P, additional, Schell, Wiley A, additional, Schefler, Amy C, additional, Scheufele, Tina, additional, Schiedler, Vivian, additional, Schneider, Gretchen, additional, Schroeder, Alison, additional, Schuchard, Ronald A, additional, Schuman, Joel S, additional, Schwab, Ivan R, additional, Scott, Adrienne, additional, Scott, Ingrid U, additional, Sears, Marvin L, additional, Seddon, Johanna M, additional, Seiler, Theo, additional, Selkin, Robert P, additional, Semba, Richard D, additional, Serbanescu, Irina, additional, Sexton, Briar, additional, Shaarawy, Tarek M, additional, Shah, Peter, additional, Shapiro, Aron, additional, Sharma, Savitri, additional, Shein, Jean, additional, Shetlar, Debra J, additional, Shields, M Bruce, additional, Shields, Carol L, additional, Shields, Jerry A, additional, Shingleton, Bradford J, additional, Shore, John W, additional, Shuba, Lesya M, additional, Simon, Guy J Ben, additional, Simmons, Richard J, additional, Simpson, Michael, additional, Singh, Arun D, additional, Singh, Omah S, additional, Sisley, Karen, additional, Sit, Arthur J, additional, Smerdon, David, additional, Smiddy, William E, additional, Smith, Ronald E, additional, Smith, Terry J, additional, Snebold, Neal G, additional, Sobrin, Lucia, additional, Sorenson, John A, additional, Soukiasian, Sarkis H, additional, Spaeth, George L, additional, Spaide, Richard F, additional, Srivastava, Monika, additional, Srivastava, Sunil K, additional, Stangos, Alexandros N, additional, Starck, Tomy, additional, Stark, Walter J, additional, Stein, Joshua D, additional, Steinert, Roger F, additional, Strauss, Leon, additional, Streeten, Barbara W, additional, Streilein, J Wayne, additional, Strong, James D, additional, Sugino, Ilene K, additional, Suhler, Eric B, additional, Sullivan, Timothy J, additional, Sun, Jennifer K, additional, Sunness, Janet S, additional, Sutula, Francis C, additional, Syed, Nasreen A, additional, Ta, Christopher N, additional, Takei, Hidehiro, additional, Talamo, Jonathan H, additional, Tamesis, Richard R, additional, Tamhankar, Madhura, additional, Tarbet, Kristen J, additional, Tarver-Carr, Michelle, additional, Terry, Mark A, additional, Thomas, Joseph M, additional, Thompson, Vance, additional, Thorne, Jennifer E, additional, Thurtell, Matthew J, additional, Tingey, David P, additional, To, King W, additional, Tobaigy, Faisal M, additional, Tolentino, Michael J, additional, Tong, Melissa G, additional, Torkildsen, Gail, additional, Toth, Cynthia A, additional, Traboulsi, Elias I, additional, Trucksis, Michele, additional, Tsai, James C, additional, Tsai, Julie H, additional, Tse, David T, additional, Tseng, Scheffer CG, additional, Tu, Elmer Y, additional, Udell, Ira J, additional, Valenzuela, Alejandra A, additional, Van Gelder, Russell N, additional, Van Stavern, Gregory P, additional, Vander Veen, Deborah K, additional, Vavvas, Demetrios, additional, Verity, David H, additional, Vinciguerra, Paolo, additional, Vinger, Paul F, additional, Volpe, Nicholas J, additional, Wackernagel, Werner, additional, Wadhwa, Sonal Desai, additional, Wagoner, Michael D, additional, Waheed, Nadia K, additional, Walton, David S, additional, Wand, Martin, additional, Wang, Jie Jin, additional, Warden, Scott M, additional, Webb, Lennox, additional, Weber, David, additional, Wee, Daniel, additional, Westerfeld, Corey B, additional, Westfall, Christopher T, additional, Whitcup, Scott M, additional, White, Valerie A, additional, White, William L, additional, Wickens, Jason, additional, Wiggs, Janey L, additional, Wilensky, Jacob T, additional, Wilkinson, Charles P, additional, Williams, Patrick D, additional, Wilson, David J, additional, Wilson, M Roy, additional, Wilson, Steven E, additional, Winokur, Jules, additional, Wirostko, William J, additional, Wollstein, Gadi, additional, Wong, Albert Chak Ming, additional, Wong, Tien Y, additional, Woog, John J, additional, Wride, Michael, additional, Wu, Carolyn S, additional, WuDunn, Darrell, additional, Yang, Jean, additional, Yannuzzi, Lawrence A, additional, Yaremchuk, Michael J, additional, Yeatts, R Patrick, additional, Yee, Richard W, additional, Yeh, Steven, additional, Young, Lucy HY, additional, Yu, Jenny Y, additional, Yue, Beatrice YJT, additional, Zacks, Charles M, additional, Zagelbaum, Bruce M, additional, Zamani, Maryam, additional, Zarbin, Marco, additional, Zografos, Leonidas, additional, and Zoumalan, Christopher I, additional
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- 2008
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11. Contracting as an Alternative Delivery System for Vocational Education
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Williams, Patrick D.
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- 1979
12. NONINFECTIOUS VITRITIS AFTER INTRAVITREAL INJECTION OF ANTI-VEGF AGENTS
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Williams, Patrick D., primary, Chong, Deborah, additional, Fuller, Timothy, additional, and Callanan, David, additional
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- 2016
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13. Evolving trends in primary retinal detachment repair: Microincisional vitrectomy and the role of OCT
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Williams, Patrick D., primary and Hariprasad, Seenu M., additional
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- 2014
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14. A prospective pilot study comparing combined intravitreal ranibizumab and half-fluence photodynamic therapy with ranibizumab monotherapy in the treatment of neovascular age-related macular degeneration
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Williams,Patrick D, Callanan,David, Solley,Wayne, Avery,Robert L, Pieramici,Dante J, Aaberg,Tom, Williams,Patrick D, Callanan,David, Solley,Wayne, Avery,Robert L, Pieramici,Dante J, and Aaberg,Tom
- Abstract
Patrick D Williams,1 David Callanan,1 Wayne Solley,1 Robert L Avery,2 Dante J Pieramici,2 Tom Aaberg31Texas Retina Associates, Dallas, TX, 2California Retina Consultants and Research Foundation, Santa Barbara, CA, 3Retinal Associates, Grand Rapids, MI, USAPurpose: This prospective multi-center pilot study compares the use of half-fluence photodynamic therapy combined with ranibizumab with ranibizumab monotherapy for the treatment of neovascular age-related macular degeneration.Methods: All patients presenting with untreated subfoveal neovascular age-related macular degeneration were considered for inclusion. Patients were randomized to receive either ranibizumab with half-fluence photodynamic therapy or ranibizumab alone. Patients in the ranibizumab alone group were given three consecutive monthly ranibizumab injections and were followed monthly. They were treated with ranibizumab as needed, based on clinical discretion, using vision and optical coherence tomography. Patients in the combined group were given one same-day combined ranibizumab and half-fluence (25 j/cm2) photodynamic therapy treatment and were treated monthly as needed. Outcomes included changes in standardized visual acuity, optical coherence tomography foveal thickness, and percentage of as-needed injections to maintenance examinations.Results: Fifty-six out of 60 enrolled patients completed the twelve month primary outcome visit; this consisted of 27 patients receiving ranibizumab alone and 29 receiving combined treatment. The average age was 79.1 for the ranibizumab alone group and 79.3 for the combined group. The mean visual acuity in the ranibizumab alone group improved from 52.9 Early Treatment of Diabetic Retinopathy letters initially to 62.8 letters at twelve months. The mean visual acuity in the combined group improved from 49.2 letters to 51.8 letters at twelve months. The differences in visual acuity improvements were not statistically significant based on a two-tailed t-test (P = 0.2). Du
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- 2012
15. Vision loss associated with the use and removal of intraocular silicone oil
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Williams,Patrick D, Fuller,Christopher G, Scott,Ingrid U, Fuller,Dwain G, Flynn Jr,Harry W, Williams,Patrick D, Fuller,Christopher G, Scott,Ingrid U, Fuller,Dwain G, and Flynn Jr,Harry W
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Patrick D Williams1, Christopher G Fuller1, Ingrid U Scott2, Dwain G Fuller1, Harry W Flynn Jr31Texas Retina Associates, Dallas, TX, USA; 2Departments of Ophthalmology and Health Evaluation Sciences, Penn State College of Medicine, Hershey, PA, USA; 3Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USAPurpose: To describe vision loss associated with the use or removal of silicone oil retinal tamponade.Methods: Records were reviewed of all patients with a decrease in visual acuity of at least 3 Snellen lines from best acuity with 5000 centistoke silicone oil in place or after removal of silicone oil at a single retina-only practice between 1996 and 2006.Results: Nine patients (6 men, 3 women) with a mean age of 48 years (range, 16–61) met study inclusion criteria. Seven patients lost at least three Snellen lines of vision while the silicone oil was in place. Four patients had late modest improvements in acuity when compared to their final recorded Snellen vision before silicone oil removal, however no patients exhibited visual improvement when comparing their final recorded visual acuities after oil removal with best recorded acuities under oil tamponade. Loss of the foveal depression was a consistent feature on optical coherence tomography.Conclusions: Vision loss is a possible complication of silicone oil use and removal. Late visual improvement may occur in some patients. Further research is warranted to elucidate the mechanism(s) of vision loss associated with the use or removal of silicone oil.Keywords: retinal tamponade, visual acuity, snellen vision, silicone oil
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- 2008
16. Level Alignments and Coupling Strengths in Conductance Histograms: The Information Content of a Single Channel Peak
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Williams, Patrick D., primary and Reuter, Matthew G., additional
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- 2013
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17. A prospective pilot study comparing combined intravitreal ranibizumab and half-fluence photodynamic therapy with ranibizumab monotherapy in the treatment of neovascular age-related macular degeneration
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Aaberg Jr., Tom, primary, Williams, Patrick D., additional, Callanan, David, additional, Solley, Wayne, additional, Avery, Robert L., additional, and Pieramici, Dante, additional
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- 2012
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18. Characterization of Water Distribution in Xanthan‐Curdlan Hydrogel Complex Using Magnetic Resonance Imaging, Nuclear Magnetic Resonance Relaxometry, Rheology, and Scanning Electron Microscopy
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Williams, Patrick D., primary, Oztop, Mecit Halil, additional, McCarthy, Michael J., additional, McCarthy, Kathryn L., additional, and Lo, Y. Martin, additional
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- 2011
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19. Tobacco biomass hydrolysate enhances coenzyme Q10 production using photosynthetic Rhodospirillum rubrum
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Tian, Yuting, primary, Yue, Tianli, additional, Yuan, Yahong, additional, Soma, Pavan K., additional, Williams, Patrick D., additional, Machado, Peter A., additional, Fu, Hong, additional, Kratochvil, Robert J., additional, Wei, Cheng-i, additional, and Lo, Y. Martin, additional
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- 2010
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20. CHARACTERIZATION OF STERILE INTRAOCULAR INFLAMMATORY RESPONSES AFTER INTRAVITREAL BEVACIZUMAB INJECTION
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Chong, Deborah Y, primary, Anand, Rajiv, additional, Williams, Patrick D, additional, Qureshi, Jawad A, additional, and Callanan, David G, additional
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- 2010
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21. MACULAR ATROPHY IN BIRDSHOT RETINOCHOROIDOPATHY
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Birch, David G, primary, Williams, Patrick D, additional, Callanan, David, additional, Wang, Robert, additional, Locke, Kirsten G, additional, and Hood, Donald C, additional
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- 2010
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22. TEXTURE STABILITY OF HYDROGEL COMPLEX CONTAINING CURDLAN GUM OVER MULTIPLE FREEZE-THAW CYCLES
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WILLIAMS, PATRICK D., primary, SADAR, LISA N., additional, and MARTIN LO, Y., additional
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- 2009
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23. Periocular Dog Bite Injuries and Responsible Care
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Burroughs, John R., primary, Soparkar, Charles N.S., additional, Patrinely, James R., additional, Williams, Patrick D., additional, and Holck, David E.E., additional
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- 2002
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24. Vision loss associated with the use and removal of intraocular silicone oil.
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Williams, Patrick D., Fuller, Christopher G., Scott, Ingrid U., Fuller, Dwain G., and Flynn Jr., Harry W.
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- 2008
25. Chapter 6.39 - Serous Detachment of the Neural Retina
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Anand, Rajiv and Williams, Patrick D.
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26. List of Contributors
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Ahmed, Iqbal ike K., Ahmed, Irma, Ai, Everett, Al-Ghoul, Ahmed, Allen, David, Alvi, Nishat P., Anand, Rajiv, Ang, Leonard P.-K., Apple, David J., Archer, Desmond B., Arnold, Anthony C., Arshinoff, Steve A., Assil, Kerry K., Atebara, Neal H., Atluri, Harvinder K.S., Augsburger, James J., Aylward, G. William, Azar, Dimitri T., Baker, Brad J., Balcer, Laura Joan, Barnett, C.J., Baumal, Caroline R., Bearelly, Srilaxmi, Benson, William E., Berger, Steven Thomas, Biswas, Jyotirmav, Bolling, James P., Bornfeld, Norbert, Bose, Swaraj, Bouchard, Charles S., Boulton, Michael E., Brandt, James D., Brodsky, Michael C., Brown, Kimberly Ellen, Brown, Gary C., Brown, Melissa M., Budenz, Donald L., Bui, Alex, Burns, Stephen K., Campolattaro, Brian N., Cantor, Louis B., Jr, Antonio Capone, Carter, Keith D., Chan, Chi-Chao, Chang, Stanley, Chao, Jennifer R., Charonis, George C., Chew, Paul T.K., Ciardella, Antonio P., Civan, Mortimer M., Clark, Abbott F., Clarke, Jonathan, Contreras, Janice E., Collin, J. Richard O., Codère, François, Corrêa, Zélia M., Cowan, Claude L., Craven, E. Randy, Cruess, Alan F., Custer, Phillip L., Dahan, Elie, Dai, Eric, Damato, Bertil E., Damji, Karim F., Davidson, Richard S., Davis, Elizabeth A., Dhaliwal, Deepinder K., Diamond, Gary R., Do, Diana V., Donahue, Sean P., Dortzbach, Richard K., Drenser, Kimberly A., Duker, Jay S., Dutton, Jonathan J., Edgington, Bryan, Eggers, Howard M., Ehlers, William, Engelbert, Michael, Espandar, Ladan, Evans, Monica, Farjo, Ayad A., Farjo, Qais Anastas, Faucett, Donald C., Feiz, Vahid, Fine, I. Howard, Fisher, Yale L., Fishman, Gerald A., Forster, David J., Fox, Gregory M., Freedman, Jeffrey, Friedman, David S., Friedman, Neil J., Friedman, Deborah I., Fu, Arthur D., Fynn-Thompson, Nicoletta, Ganatra, Jyotsom, Gayre, Gregg S., Gery, Igal, Ghanem, Ramon C., Giblin, Michael, Gigantelli, James W., Goldberg, Anna, Goldberg, Robert A., Goldberg, William, Goldberg, Ivan, Goldstein, Debra A., Goldstein, Michael H., Gonder, John R., Green, Jeffrey P., Greven, Craig M., Gross, Nicole E., Gross, Ronald L., Grover, Sandeep, Guercio, Jason R., Gupta, Vishali, Gupta, Amod, Gurkan, Sevgi, Guthoff, Rudolf E., Hallak, Joelle, Haller, Julia A., Hamilton, Richard S., Harbour, J. William, Hardten, David R., Harris, Alon, Hedges Jr, Thomas R., Heier, Jeffrey S., Henderson, Polly A., Herndon, Leon W., Hitchings, Roger A., Ho, Allen C., Hoffman, Richard S., Holz, Huck A., Howard, Gene R., Howes, Frank W., Hsu, Jason, Hurwitz, Jeffrey J., Inomata, Hajime, Ip, Michael, Isaacs, Robert T., Izak, Andrea M., Jampel, Henry, Jampol, Lee M., Jiyamapa, Julia, Johnson, Chris A., Johnson, T. Mark, Johnson, Mark W., Jones, Nicholas, Kahook, Malik, Kanner, Elliott M., Kapusta, Michael A., Kardon, Randy, Karp, Carol L., Kass, Michael, Katz, L. Jay, Kaufman, Paul L., Khan, Baseer, Khaw, Peng Tee, Kim, Gene, Kimura, Alan E., Kitzmann, Anna, Klancnik, James M., Jr., Koch, Douglas D., Kohnen, Thomas, Kojima, Takashi, Kornmehl, Ernest W., Kramarevsky, Natalia, Labbe, Thad, Lane, Stephen S., Lavin, Patrick J.M., Lawton, Andrew, Lee, Paul P., Leen, Martha Motuz, Levinson, Ralph, Lim, Ridia, Lingua, Robert W., Lipham, William J., Lopez, Pedro F., Lundstrom, Mats, Magnante, Peter, Mandava, Naresh, Marak, George E., Jr., Marmor, Michael F., Marten, Lisa, Mathura, Jeevan R., Jr., Martidis, Adam, Mattox, Cynthia, McDermott, Mark L., McLeod, Stephen D., Mejico, Luis J., Meyers, Sanford M., Mieler, William F., Migdal, Clive S., Miller, David, Miller, Russell, Mimura, Tatsuya, Mittra, Robert A., Moorthy, Ramana S., Morley, Michael G., Morse, Lawrence S., Moshirfar, Majid, Moster, Mark L., Nehls Rikkers, Sarah M., Neff, Ann G., Newlin, Anna C., Noble, Kenneth G., Noecker, Robert J., Okada, Annabelle A., Olson, Jeffrey L., Opalinski, Yvonne A.V., Packer, Mark, Pandey, Suresh K., Patel, Vivek Ravindra, Pavesio, Carlos E., Pineles, Stacy, Piva, Alfio, Piltz-Seymour, Jody, Pollack, John S., Prall, F. Ryan, Price, Marianne O., Price, Francis W., Primack, Jonathan D., Pruett, Ronald C., Puliafito, Carmen A., Pulido, Jose S., Quiros, Peter A., Ramulu, Pradeep, Ramos-Esteban, Jerome C., Rao, P. Kumar, Rao, Narsing A., Read, Russell W., Rechtman, Ehud, Regillo, Carl D., Reichel, Elias, Rhee, Douglas J., Rhee, Steven S., Rheinstrom, Stephen D., Riedel, Patrick J., Rikkers, Sarah M., Robinson, Fiona O., Rodriguez-Coleman, Hannah, Rogers, Adam, Roe, Richard, Roh, Shiyoung, Rosen, Emanuel S., Rosenblatt, Brett, Rosenfeld, Philip J., Rubenstein, Jonathan B., Rubin, Steven E., Rubin, Richard M., Rubsamen, Patrick E., Saadati, Hossein G., Sadun, Alfredo A., Salim, Sarwat, Salinas, Humberto, Samuelson, Thomas W., Sanborn, George E., Sarmiento, Jerome S., Scheufele Cleary, Tina A., Schor, Paulo, Schubert, Hermann D., Schuman, Joel, Schwab, Ivan R., Schwartz, Gary S., Scott, Clifford A., Sebag, Jerry, See, Jovina L.S., Selkin, Robert P., Shields, Bruce, Shingleton, Bradford, Sierra, Patricia B., Sieving, Paul A., Sivalingam, Arunan, Small, Kent W., Smiddy, William E., Soong, Kaz, Soukiasian, Sarkis, Spaide, Richard F., Spoor, Thomas C., Stasi, Kalliopi, Steel, David, Stein, Joshua D., Steinemann, Thomas L., Suchecki, Jeanine, Sugar, Joel, Sugar, Alan, Tan, J.C.H., Tanenbaum, Myron, Taravella, Michael J., Tasman, William S., Telander, David G., Tennant, Matthew T.S., Tessler, Howard H., Thall, Edmond H., Tingey, David P., Tobaigy, Faisal M., Truong, Steven, Tsai, James C., Tsai, Julie, Tsiaras, William G., Tu, Elmer Y., Tucker, Nancy, Tuli, Sonal S., Valluri, Shailaja, Vander, James F., Vaughn, Gregory J., Virasch, Vanee Val, Wadia, Hormuz P., Walker, Rebecca S., Walton, David Sellers, Wang, Li, Wang, Frederick M., Wang, Ming X., Wang, Robert C., Wax, Martin, Weinberg, David V., Weinstein, Joel M., Weiter, John J., Werner, Liliana, Wevill, Mark T., White, Paul F., Wiggs, Janey L., Wilkinson, Charles P., Williams, Patrick D., Williams, George A., Wirostko, William J., Wollstein, Gadi, Yee, Robert D., Young, Joshua A., and Zamir, Ehud
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27. A prospective pilot study comparing combined intravitreal ranibizumab and half-fluence photodynamic therapy with ranibizumab monotherapy in the treatment of neovascular age-related macular degeneration.
- Author
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Williams PD, Callanan D, Solley W, Avery RL, Pieramici DJ, and Aaberg T
- Abstract
Purpose: This prospective multi-center pilot study compares the use of half-fluence photodynamic therapy combined with ranibizumab with ranibizumab monotherapy for the treatment of neovascular age-related macular degeneration., Methods: All patients presenting with untreated subfoveal neovascular age-related macular degeneration were considered for inclusion. Patients were randomized to receive either ranibizumab with half-fluence photodynamic therapy or ranibizumab alone. Patients in the ranibizumab alone group were given three consecutive monthly ranibizumab injections and were followed monthly. They were treated with ranibizumab as needed, based on clinical discretion, using vision and optical coherence tomography. Patients in the combined group were given one same-day combined ranibizumab and half-fluence (25 j/cm(2)) photodynamic therapy treatment and were treated monthly as needed. Outcomes included changes in standardized visual acuity, optical coherence tomography foveal thickness, and percentage of as-needed injections to maintenance examinations., Results: Fifty-six out of 60 enrolled patients completed the twelve month primary outcome visit; this consisted of 27 patients receiving ranibizumab alone and 29 receiving combined treatment. The average age was 79.1 for the ranibizumab alone group and 79.3 for the combined group. The mean visual acuity in the ranibizumab alone group improved from 52.9 Early Treatment of Diabetic Retinopathy letters initially to 62.8 letters at twelve months. The mean visual acuity in the combined group improved from 49.2 letters to 51.8 letters at twelve months. The differences in visual acuity improvements were not statistically significant based on a two-tailed t-test (P = 0.2). Due to the presence of outliers in each group, a Mann-Whitney U test was performed to confirm the results (U = 325; P = 0.28). The mean optical coherence tomography foveal thickness improved 92.5 microns and 106.7 microns in the ranibizumab alone and the combined group, respectively. The difference was not significant based on a two-tailed t-test (P = 0.6). The ranibizumab alone group received an average of 6.8 injections, while the combined group received an average of three injections. This difference was not significant based on a chi-square test (P = 0.11)., Conclusion: The groups appeared similar based on statistical analysis, but larger studies are needed to determine possible small differences between combination therapy and monotherapy.
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- 2012
- Full Text
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