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47 results on '"Williams, Jeanne V.A."'

26. Association Between Excess Sleep Duration and Risk of Stroke: A Population-Based Study

Author

Joundi, Raed A., Patten, Scott B., Williams, Jeanne V.A., and Smith, Eric E.

Abstract

Abstract:Background:Excess sleep is associated with higher risk of stroke, but whether the risk is modified by age and if it remains elevated after accounting for the competing risk of death is not well understood.Methods:We used nine years of the Canadian Community Health Survey between 2000 to 2016 to obtain self-reported sleep duration and created a cohort of individuals without prior stroke, heart disease, or cancer. We linked to hospital records to determine subsequent admissions or emergency department visits for acute stroke until December 31, 2017. We used Cox proportional hazard models to determine the association between sleep duration and risk of stroke, assessing for modification by age and sex and adjusting for demographic, vascular, and social factors. We obtained cumulative incidence of stroke accounting for the competing risk of death.Results:There were 82,795 individuals in our cohort who met inclusion criteria and had self-reported sleep duration, with 1705 stroke events in follow-up. There was an association between excess sleep (≥10 h/night) and risk of stroke in those <70 years (fully adjusted hazard ratio 2.29, 95% CI 1.04–5.06), but not ≥70 years of age, with a similar association after accounting for the competing risk of death.Conclusion:Sleep duration ≥10 h/night is associated with increased risk of stroke in those <70 years of age. The findings support current guidelines for 7–9 h of sleep per night. Further research is needed to elucidate the relationship between sleep and cerebrovascular disease.

Published
2023
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45. Mood and anxiety disorders, the association with presenteeism in employed members of a general population sample

Author

Esposito, Eleonora, Wang, Jian Li, Williams, Jeanne V.A., and Patten, Scott B.

Abstract

SummaryAims– The term “presenteeism” is used to describe workers who are present in the workforce, but who are not functioning at full capacity. The objective of the study was to describe the impact of mood and anxiety disorders on presenteeism in a population sample. Methods– Random digit dialing was used to select a sample of n= 3345 subjects between the ages of 18 and 64. A computer assisted telephone interview that included the Mini Neuropsychiatric Diagnostic Interview(MINI), the Stanford Presenteeism Scale6 (SPS-6) and a pharmacoepidemiology module was administered. Results– Among subjects with comorbid mood and anxiety disorders 75.0% reported interference with their work compared with only 13.3% of subjects without mood or anxiety disorders. Mood and anxiety disorders were associated with lower presenteeism ratings. Regression analysis uncovered a significant gender by anxiety disorder interaction, indicating that the effect of anxiety disorders was greater in men than women. Conclusions– This is the first study to report the impact of mental disorders on presenteeism in a general population sample. The results confirm that the problem of presenteeism is not restricted to specific occupational groups, but is instead a widespread problem in the general population.Declaration of Interest: This study was funded by the Alberta Depression Initiative through the Institute of Health Economics (www.ihe.ab.ca). Dr. Esposito was supported by an International Resident Fellowship from the University of Calgary. Dr. Patten is a Health Scholar with the Alberta Heritage Foundation for Medical Research and a Fellow with the Institute of Health Economics. Dr. Wang is a New Investigator with the Canadian Institutes for Health Research.

Published
2007
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