823 results on '"Williams, Denise"'
Search Results
2. Evidence-Based Care for the Elderly: Uses of “the Grandmother Principle”
- Author
-
Williams, Samuel K., Braxton, Joanne M., Gosdin, Melissa, Nobis, Nathan, and Williams, Denise A.
- Published
- 2017
- Full Text
- View/download PDF
3. Inclusion in the workplace: an integrative literature review
- Author
-
Nguyen, Loi Anh, Evan, Rebecca, Chaudhuri, Sanghamitra, Hagen, Marcia, and Williams, Denise
- Published
- 2024
- Full Text
- View/download PDF
4. How Community Colleges Can Support Student Mental Health Needs. Research Brief. RB-A2552-1
- Author
-
RAND Education and Labor, Sontag-Padilla, Lisa, Williams, Denise, Kosiewicz, Holly, Daugherty, Lindsay, Kane, Heidi, Gripshover, Sarah, and Miller, Trey
- Abstract
The United States faces an unprecedented mental health crisis, with youth and young adults at the center. Even before the coronavirus disease 2019 (COVID-19) pandemic, nearly 50 percent of college students reported at least one mental health concern. Without adequate mental health support, college students, including those at community colleges, may be at risk for a variety of academic and nonacademic consequences that negatively affect their overall well-being, including lower college completion rates, higher rates of substance use, and lower lifetime earning potential. This research brief describes a study examining eight community colleges from across the United States which found that, although the institutions did offer mental health services, most lacked a clear organizing framework for those efforts, and that financial challenges limited the support offered to students. The research also highlighted the importance of community college leaders explicitly prioritizing student mental health, as well as broad staff buy-in to the effort. [For the full report, "Supporting the Mental Health Needs of Community College Students. Research Report. RR-A2552-1," see ED627480.]
- Published
- 2023
- Full Text
- View/download PDF
5. Supporting the Mental Health Needs of Community College Students. Research Report. RR-A2552-1
- Author
-
RAND Education and Labor, RAND Social and Economic Well-Being, RAND Health, Sontag-Padilla, Lisa, Williams, Denise, Kosiewicz, Holly, Daugherty, Lindsay, Kane, Heidi, Gripshover, Sarah, and Miller, Trey
- Abstract
The United States faces an unprecedented mental health crisis, with youth and young adults at the center. Even before the COVID-19 pandemic, nearly 50 percent of college students reported at least one mental health concern. The COVID-19 pandemic notably exacerbated these issues and underscored the urgent need to identify and implement ways to ameliorate the youth mental health crisis. In 2021, the National Academies of Sciences, Engineering, and Medicine called on the field of higher education to address growing concerns about student mental health by identifying and elevating emerging and promising approaches that offer a more holistic way to support students' mental health. Serving as the main entry point for more than 40 percent of students seeking a postsecondary degree, community colleges represent a tremendous and untapped opportunity to better address mental health in the United States, particularly for students who have been traditionally underserved (e.g., students of color, first-generation students, and low-income students). However, community colleges have limited evidence and guidance to inform the implementation of multilevel, holistic approaches to support students with varying mental health needs. To address this knowledge gap, this report shares a descriptive study of eight community colleges at the forefront of implementing multilevel approaches (a combination of prevention, early intervention, and treatment services) to support student mental health, as well as key facilitators for and barriers to their success. [For "How Community Colleges Can Support Student Mental Health Needs. Research Brief. RB-A2552-1," see ED627489.]
- Published
- 2023
- Full Text
- View/download PDF
6. Biallelic CRELD1 variants cause a multisystem syndrome, including neurodevelopmental phenotypes, cardiac dysrhythmias, and frequent infections
- Author
-
Borras, Silvia, Clark, Caroline, Dean, John, Miedzybrodzka, Zosia, Ross, Alison, Tennant, Stephen, Dabir, Tabib, Donnelly, Deirdre, Humphreys, Mervyn, Magee, Alex, McConnell, Vivienne, McKee, Shane, McNerlan, Susan, Morrison, Patrick J., Rea, Gillian, Stewart, Fiona, Cole, Trevor, Cooper, Nicola, Cooper-Charles, Lisa, Cox, Helen, Islam, Lily, Jarvis, Joanna, Keelagher, Rebecca, Lim, Derek, McMullan, Dominic, Morton, Jenny, Naik, Swati, O’Driscoll, Mary, Ong, Kai-Ren, Osio, Deborah, Ragge, Nicola, Turton, Sarah, Vogt, Julie, Williams, Denise, Bodek, Simon, Donaldson, Alan, Hills, Alison, Low, Karen, Newbury-Ecob, Ruth, Norman, Andrew M., Roberts, Eileen, Scurr, Ingrid, Smithson, Sarah, Tooley, Madeleine, Abbs, Steve, Armstrong, Ruth, Dunn, Carolyn, Holden, Simon, Park, Soo-Mi, Paterson, Joan, Raymond, Lucy, Reid, Evan, Sandford, Richard, Simonic, Ingrid, Tischkowitz, Marc, Woods, Geoff, Bradley, Lisa, Comerford, Joanne, Green, Andrew, Lynch, Sally, McQuaid, Shirley, Mullaney, Brendan, Berg, Jonathan, Goudie, David, Mavrak, Eleni, McLean, Joanne, McWilliam, Catherine, Reavey, Eleanor, Azam, Tara, Cleary, Elaine, Jackson, Andrew, Lam, Wayne, Lampe, Anne, Moore, David, Porteous, Mary, Baple, Emma, Baptista, Júlia, Brewer, Carole, Castle, Bruce, Kivuva, Emma, Owens, Martina, Rankin, Julia, Shaw-Smith, Charles, Turner, Claire, Turnpenny, Peter, Tysoe, Carolyn, Bradley, Therese, Davidson, Rosemarie, Gardiner, Carol, Joss, Shelagh, Kinning, Esther, Longman, Cheryl, McGowan, Ruth, Murday, Victoria, Pilz, Daniela, Tobias, Edward, Whiteford, Margo, Williams, Nicola, Barnicoat, Angela, Clement, Emma, Faravelli, Francesca, Hurst, Jane, Jenkins, Lucy, Jones, Wendy, Ajith Kumar, V.K., Lees, Melissa, Loughlin, Sam, Male, Alison, Morrogh, Deborah, Rosser, Elisabeth, Scott, Richard, Wilson, Louise, Beleza, Ana, Deshpande, Charu, Flinter, Frances, Holder, Muriel, Irving, Melita, Izatt, Louise, Josifova, Dragana, Mohammed, Shehla, Molenda, Aneta, Robert, Leema, Roworth, Wendy, Ruddy, Deborah, Ryten, Mina, Yau, Shu, Bennett, Christopher, Blyth, Moira, Campbell, Jennifer, Coates, Andrea, Dobbie, Angus, Hewitt, Sarah, Hobson, Emma, Jackson, Eilidh, Jewell, Rosalyn, Kraus, Alison, Prescott, Katrina, Sheridan, Eamonn, Thomson, Jenny, Bradshaw, Kirsty, Dixit, Abhijit, Eason, Jacqueline, Haines, Rebecca, Harrison, Rachel, Mutch, Stacey, Sarkar, Ajoy, Searle, Claire, Shannon, Nora, Sharif, Abid, Suri, Mohnish, Vasudevan, Pradeep, Canham, Natalie, Ellis, Ian, Greenhalgh, Lynn, Howard, Emma, Stinton, Victoria, Swale, Andrew, Weber, Astrid, Banka, Siddharth, Breen, Catherine, Briggs, Tracy, Burkitt-Wright, Emma, Chandler, Kate, Clayton-Smith, Jill, Donnai, Dian, Douzgou, Sofia, Gaunt, Lorraine, Jones, Elizabeth, Kerr, Bronwyn, Langley, Claire, Metcalfe, Kay, Smith, Audrey, Wright, Ronnie, Bourn, David, Burn, John, Fisher, Richard, Hellens, Steve, Henderson, Alex, Montgomery, Tara, Splitt, Miranda, Straub, Volker, Wright, Michael, Zwolinski, Simon, Allen, Zoe, Bernhard, Birgitta, Brady, Angela, Brooks, Claire, Busby, Louise, Clowes, Virginia, Ghali, Neeti, Holder, Susan, Ibitoye, Rita, Wakeling, Emma, Blair, Edward, Carmichael, Jenny, Cilliers, Deirdre, Clasper, Susan, Gibbons, Richard, Kini, Usha, Lester, Tracy, Nemeth, Andrea, Poulton, Joanna, Price, Sue, Shears, Debbie, Stewart, Helen, Wilkie, Andrew, Albaba, Shadi, Baker, Duncan, Balasubramanian, Meena, Johnson, Diana, Parker, Michael, Quarrell, Oliver, Stewart, Alison, Willoughby, Josh, Crosby, Charlene, Elmslie, Frances, Homfray, Tessa, Jin, Huilin, Lahiri, Nayana, Mansour, Sahar, Marks, Karen, McEntagart, Meriel, Saggar, Anand, Tatton-Brown, Kate, Butler, Rachel, Clarke, Angus, Corrin, Sian, Fry, Andrew, Kamath, Arveen, McCann, Emma, Mugalaasi, Hood, Pottinger, Caroline, Procter, Annie, Sampson, Julian, Sansbury, Francis, Varghese, Vinod, Baralle, Diana, Callaway, Alison, Cassidy, Emma J., Daniels, Stacey, Douglas, Andrew, Foulds, Nicola, Hunt, David, Kharbanda, Mira, Lachlan, Katherine, Mercer, Catherine, Side, Lucy, Temple, I. Karen, Wellesley, Diana, Ambrose, J.C., Arumugam, P., Baple, E.L., Bleda, M., Boardman-Pretty, F., Boissiere, J.M., Boustred, C.R., Caulfield, M.J., Chan, G.C., Craig, C.E.H., Daugherty, L.C., de Burca, A., Devereau, A., Elgar, G., Foulger, R.E., Fowler, T., FurióTarí, P., Hackett, J.M., Halai, D., Hamblin, A., Henderson, S., Holman, J.E., Hubbard, T.J.P., Ibáñez, K., Jackson, R., Jones, L.J., Kasperaviciute, D., Kayikci, M., Lahnstein, L., Lawson, K., Leigh, S.E.A., Leong, I.U.S., Lopez, F.J., MaleadyCrowe, F., Mason, J., McDonagh, E.M., Moutsianas, L., Mueller, M., Murugaesu, N., Need, A.C., Odhams, C.A., Patch, C., Perez-Gil, D., Polychronopoulos, D., Pullinger, J., Rahim, T., Rendon, A., Riesgo-Ferreiro, P., Rogers, T., Ryten, M., Savage, K., Sawant, K., Scott, R.H., Siddiq, A., Sieghart, A., Smedley, D., Smith, K.R., Sosinsky, A., Spooner, W., Stevens, H.E., Stuckey, A., Sultana, R., Thomas, E.R.A., Thompson, S.R., Tucci, A., Walsh, E., Watters, S.A., Welland, M.J., Williams, E., Witkowska, K., Acosta, Maria T., Adam, Margaret, Adams, David R., Agrawal, Pankaj B., Alejandro, Mercedes E., Alvey, Justin, Amendola, Laura, Andrews, Ashley, Ashley, Euan A., Azamian, Mahshid S., Bacino, Carlos A., Bademci, Guney, Baker, Eva, Balasubramanyam, Ashok, Baldridge, Dustin, Bale, Jim, Bamshad, Michael, Barbouth, Deborah, Bayrak-Toydemir, Pinar, Beck, Anita, Beggs, Alan H., Behrens, Edward, Bejerano, Gill, Bennet, Jimmy, Berg-Rood, Beverly, Bernstein, Jonathan A., Berry, Gerard T., Bican, Anna, Bivona, Stephanie, Blue, Elizabeth, Bohnsack, John, Bonnenmann, Carsten, Bonner, Devon, Botto, Lorenzo, Boyd, Brenna, Briere, Lauren C., Brokamp, Elly, Brown, Gabrielle, Burke, Elizabeth A., Burrage, Lindsay C., Butte, Manish J., Byers, Peter, Byrd, William E., Carey, John, Carrasquillo, Olveen, Peter Chang, Ta Chen, Chanprasert, Sirisak, Chao, Hsiao-Tuan, Clark, Gary D., Coakley, Terra R., Cobban, Laurel A., Cogan, Joy D., Coggins, Matthew, Cole, F. Sessions, Colley, Heather A., Cooper, Cynthia M., Craigen, William J., Crouse, Andrew B., Cunningham, Michael, D'Souza, Precilla, Dai, Hongzheng, Dasari, Surendra, Davids, Mariska, Dayal, Jyoti G., Deardorff, Matthew, Dell'Angelica, Esteban C., Dhar, Shweta U., Dipple, Katrina, Doherty, Daniel, Dorrani, Naghmeh, Douine, Emilie D., Draper, David D., Duncan, Laura, Earl, Dawn, Eckstein, David J., Emrick, Lisa T., Eng, Christine M., Esteves, Cecilia, Estwick, Tyra, Falk, Marni, Fernandez, Liliana, Ferreira, Carlos, Fieg, Elizabeth L., Findley, Laurie C., Fisher, Paul G., Fogel, Brent L., Forghani, Irman, Fresard, Laure, Gahl, William A., Glass, Ian, Godfrey, Rena A., Golden-Grant, Katie, Goldman, Alica M., Goldstein, David B., Grajewski, Alana, Groden, Catherine A., Gropman, Andrea L., Gutierrez, Irma, Hahn, Sihoun, Hamid, Rizwan, Hanchard, Neil A., Hassey, Kelly, Hayes, Nichole, High, Frances, Hing, Anne, Hisama, Fuki M., Holm, Ingrid A., Hom, Jason, Horike-Pyne, Martha, Huang, Alden, Huang, Yong, Isasi, Rosario, Jamal, Fariha, Jarvik, Gail P., Jarvik, Jeffrey, Jayadev, Suman, Johnston, Jean M., Karaviti, Lefkothea, Kelley, Emily G., Kennedy, Jennifer, Kiley, Dana, Kohane, Isaac S., Kohler, Jennefer N., Krakow, Deborah, Krasnewich, Donna M., Kravets, Elijah, Korrick, Susan, Koziura, Mary, Krier, Joel B., Lalani, Seema R., Lam, Byron, Lam, Christina, Lanpher, Brendan C., Lanza, Ian R., Lau, C. Christopher, LeBlanc, Kimberly, Lee, Brendan H., Lee, Hane, Levitt, Roy, Lewis, Richard A., Lincoln, Sharyn A., Liu, Pengfei, Liu, Xue Zhong, Longo, Nicola, Loo, Sandra K., Loscalzo, Joseph, Maas, Richard L., Macnamara, Ellen F., MacRae, Calum A., Maduro, Valerie V., Majcherska, Marta M., Mak, Bryan, Malicdan, May Christine V., Mamounas, Laura A., Manolio, Teri A., Mao, Rong, Maravilla, Kenneth, Markello, Thomas C., Marom, Ronit, Marth, Gabor, Martin, Beth A., Martin, Martin G., Martínez-Agosto, Julian A., Marwaha, Shruti, McCauley, Jacob, McCormack, Colleen E., McCray, Alexa T., McGee, Elisabeth, Mefford, Heather, Merritt, J. Lawrence, Might, Matthew, Mirzaa, Ghayda, Morava, Eva, Moretti, Paolo M., Morimoto, Marie, Mulvihill, John J., Murdock, David R., Nakano-Okuno, Mariko, Nath, Avi, Nelson, Stan F., Newman, John H., Nicholas, Sarah K., Nickerson, Deborah, Nieves-Rodriguez, Shirley, Novacic, Donna, Oglesbee, Devin, Orengo, James P., Pace, Laura, Pak, Stephen, Pallais, J. Carl, Papp, Jeanette C., Parker, Neil H., Phillips, John A., Posey, Jennifer E., Potocki, Lorraine, Pusey, Barbara N., Quinlan, Aaron, Raskind, Wendy, Raja, Archana N., Rao, Deepak A., Renteria, Genecee, Reuter, Chloe M., Rives, Lynette, Robertson, Amy K., Rodan, Lance H., Rosenfeld, Jill A., Rosenwasser, Natalie, Ruzhnikov, Maura, Sacco, Ralph, Sampson, Jacinda B., Samson, Susan L., Saporta, Mario, Scott, C. Ron, Schaechter, Judy, Schedl, Timothy, Scott, Daryl A., Sharma, Prashant, Shin, Jimann, Signer, Rebecca, Sillari, Catherine H., Silverman, Edwin K., Sinsheimer, Janet S., Sisco, Kathy, Smith, Edward C., Smith, Kevin S., Solem, Emily, Solnica-Krezel, Lilianna, Stoler, Joan M., Stong, Nicholas, Sullivan, Jennifer A., Sun, Angela, Sutton, Shirley, Sweetser, David A., Sybert, Virginia, Tabor, Holly K., Tamburro, Cecelia P., Tekin, Mustafa, Telischi, Fred, Thorson, Willa, Tifft, Cynthia J., Toro, Camilo, Tran, Alyssa A., Tucker, Brianna M., Urv, Tiina K., Vanderver, Adeline, Velinder, Matt, Viskochil, Dave, Vogel, Tiphanie P., Wahl, Colleen E., Wallace, Stephanie, Walley, Nicole M., Walsh, Chris A., Walker, Melissa, Wambach, Jennifer, Wan, Jijun, Wang, Lee-Kai, Wangler, Michael F., Ward, Patricia A., Wegner, Daniel, Wener, Mark, Wenger, Tara, Perry, Katherine Wesseling, Westerfield, Monte, Wheeler, Matthew T., Whitlock, Jordan, Wolfe, Lynne A., Woods, Jeremy D., Yamamoto, Shinya, Yang, John, Yu, Guoyun, Zastrow, Diane B., Zhao, Chunli, Zuchner, Stephan, Jeffries, Lauren, Mis, Emily K., McWalter, Kirsty, Donkervoort, Sandra, Brodsky, Nina N., Carpier, Jean-Marie, Ji, Weizhen, Ionita, Cristian, Roy, Bhaskar, Morrow, Jon S., Darbinyan, Armine, Iyer, Krishna, Aul, Ritu B., Chao, Katherine R., Cobbold, Laura, Cohen, Stacey, Custodio, Helena M., Drummond-Borg, Margaret, Finanger, Erika, Hainline, Bryan E., Helbig, Ingo, Hewson, Stacy, Hu, Ying, Jackson, Adam, Konstantino, Monica, Leach, Meganne E., McCormick, David, Nelson, Stanley, Nguyen, Joanne, Nugent, Kimberly, Ortega, Lucy, Goodkin, Howard P., Roeder, Elizabeth, Roy, Sani, Sapp, Katie, Saade, Dimah, Sisodiya, Sanjay M., Stals, Karen, Towner, Shelley, Wilson, William, Khokha, Mustafa K., Bönnemann, Carsten G., Lucas, Carrie L., and Lakhani, Saquib A.
- Published
- 2024
- Full Text
- View/download PDF
7. Student Perceptions of an Accelerated Online Master's in Education Administration Program through the Lens of Social Presence
- Author
-
Soles, Brooke and Maduli-Williams, Denise
- Abstract
The purpose of this study is to analyze student perceptions of the success of an online accelerated Master's in Educational Administration (MAEd) program through the lens of social presence by asking the following question: What are student perceptions of teaching and learning in an accelerated MAEd program? Forty-eight graduate students in an accelerated, one-year MAEd program were surveyed to identify their perceptions. Findings from the study indicated that emotional expression, open communication, and group cohesion were key elements in student perceptions of teaching and learning in their online MAEd program.
- Published
- 2019
8. Leadership Coaching in Surgical Residency: Reasons for Referral and Topics Addressed to Improve Nontechnical Skill
- Author
-
Pepe, Russell J., Diggs, Laurence, Foley, Frederick W., Moore, Thomas, Williams, Denise A., and Patel, Nell Maloney
- Published
- 2023
- Full Text
- View/download PDF
9. Suicide Postvention in Schools: What Evidence Supports Our Current National Recommendations
- Author
-
Williams, Denise Yookong, Wexler, Lisa, and Mueller, Anna S.
- Abstract
Suicide is a leading cause of death for school-aged preteens and adolescents and a growing risk for younger children. Schools are the ubiquitous institutional context serving this age group. These trends suggest a need for knowledge and guidance related to school postvention efforts, yet the available research is limited. Focusing on postvention, or the period after a peer suicide occurs, is critical to youth suicide prevention because this is a time of elevated suicide risk for youth. Targeted postvention interventions in schools can mitigate youth suicide risk and limit contagion within a school's student body. This article explores the scientific literature related to school-based suicide postvention, describing the strength and limits of research supporting common recommendations for suicide postvention in schools. It identifies widespread recommendations for school postvention that have only preliminary supportive evidence and notes several areas in need of additional research. With clearer postvention best practices to guide their suicide crisis preparedness plans and postvention procedures, schools can better support students, families, and the community as a whole in order to prevent further tragedies.
- Published
- 2022
10. Prenatal next-generation sequencing in the fetus with congenital malformations: how can we improve clinical utility?
- Author
-
Kilby, Mark D., Morgan, Sian, Mone, Fionnuala, and Williams, Denise
- Published
- 2023
- Full Text
- View/download PDF
11. Association of Medicaid Expansion and Health Insurance with Receipt of Smoking Cessation Services and Smoking Behaviors in Substance Use Disorder Treatment
- Author
-
Yip, Deborah, Gubner, Noah, Le, Thao, Williams, Denise, Delucchi, Kevin, and Guydish, Joseph
- Subjects
Clinical and Health Psychology ,Psychology ,Tobacco Smoke and Health ,Prevention ,Clinical Research ,Basic Behavioral and Social Science ,Behavioral and Social Science ,Drug Abuse (NIDA only) ,Tobacco ,Substance Misuse ,Health Services ,Brain Disorders ,Respiratory ,Good Health and Well Being ,Adult ,Female ,Health Services Accessibility ,Humans ,Insurance Coverage ,Insurance ,Health ,Male ,Medicaid ,Middle Aged ,Patient Protection and Affordable Care Act ,Smoking ,Smoking Cessation ,Socioeconomic Factors ,Substance-Related Disorders ,Tobacco Use Disorder ,United States ,Public Health and Health Services ,Social Work ,Psychiatry ,Health services and systems ,Clinical and health psychology - Abstract
This study examined whether living in a Medicaid-expanded state or having health insurance was associated with receipt of smoking cessation services or smoking behaviors among substance use disorder (SUD) treatment clients. In 2015 and 2016, 1702 SUD clients in 14 states were surveyed for health insurance status, smoking cessation services received in their treatment program, and smoking behaviors. Services and behaviors were then compared by state Medicaid expansion and health insurance status independently. Clients in Medicaid-expanded states were more likely to be insured (89.9% vs. 54.4%, p
- Published
- 2020
12. The majority of autosomal recessive nanophthalmos and posterior microphthalmia can be attributed to biallelic sequence and structural variants in MFRP and PRSS56.
- Author
-
Almoallem, Basamat, Arno, Gavin, De Zaeytijd, Julie, Verdin, Hannah, Balikova, Irina, Casteels, Ingele, de Ravel, Thomy, Hull, Sarah, Suzani, Martina, Destrée, Anne, Peng, Michelle, Williams, Denise, Ainsworth, John R, Webster, Andrew R, Leroy, Bart P, Moore, Anthony T, and De Baere, Elfride
- Subjects
Humans ,Microphthalmos ,Membrane Proteins ,Cohort Studies ,Family ,Heterozygote ,Mutation ,Alleles ,Adolescent ,Adult ,Aged ,Middle Aged ,Child ,Child ,Preschool ,Female ,Male ,DNA Copy Number Variations ,Serine Proteases ,Whole Genome Sequencing - Abstract
This study aimed to genetically and clinically characterize a unique cohort of 25 individuals from 21 unrelated families with autosomal recessive nanophthalmos (NNO) and posterior microphthalmia (MCOP) from different ethnicities. An ophthalmological assessment in all families was followed by targeted MFRP and PRSS56 testing in 20 families and whole-genome sequencing in one family. Three families underwent homozygosity mapping using SNP arrays. Eight distinct MFRP mutations were found in 10/21 families (47.6%), five of which are novel including a deletion spanning the 5' untranslated region and the first coding part of exon 1. Most cases harbored homozygous mutations (8/10), while a compound heterozygous and a monoallelic genotype were identified in the remaining ones (2/10). Six distinct PRSS56 mutations were found in 9/21 (42.9%) families, three of which are novel. Similarly, homozygous mutations were found in all but one, leaving 2/21 families (9.5%) without a molecular diagnosis. Clinically, all patients had reduced visual acuity, hyperopia, short axial length and crowded optic discs. Retinitis pigmentosa was observed in 5/10 (50%) of the MFRP group, papillomacular folds in 12/19 (63.2%) of MCOP and in 3/6 (50%) of NNO cases. A considerable phenotypic variability was observed, with no clear genotype-phenotype correlations. Overall, our study represents the largest NNO and MCOP cohort reported to date and provides a genetic diagnosis in 19/21 families (90.5%), including the first MFRP genomic rearrangement, offering opportunities for gene-based therapies in MFRP-associated disease. Finally, our study underscores the importance of sequence and copy number analysis of the MFRP and PRSS56 genes in MCOP and NNO.
- Published
- 2020
13. Tobacco-free grounds implementation in California residential substance use disorder (SUD) treatment programs.
- Author
-
Guydish, Joseph, Wahleithner, Jennifer, Williams, Denise, and Yip, Deborah
- Subjects
Tobacco cessation services ,addiction treatment ,policy ,smoking ,Substance Abuse ,Public Health and Health Services ,Psychology - Abstract
Smoke-free laws and policies have contributed significantly to the decline in smoking in the U.S, but are not often applied in high-prevalence smoking populations where they are most needed. Smoking among clients in publicly funded substance use disorder (SUD) treatment is 3-4 times higher than the general population, and little is known about tobacco policies programs have adopted. To identify the prevalence of tobacco-free grounds and other smoking policies in California's publicly funded, adult, residential SUD programs. Using a California DHCS contact list of 1,921 publicly funded, non-medical, SUD programs, 362 were eligible to participate in a brief semi-structured phone survey concerning indoor and outdoor smoking for staff and clients and other tobacco policies. Of 259 programs that completed the survey, 28 (10.8%) reported tobacco-free grounds. 91 (35.1%) expressed interest in implementing tobacco-free policies and 23 have plans to do so. Nearly all programs (n = 253, 97.7%) had some policy restricting e-cigarette use, and 110 (43.5%) of these reported a complete ban on e-cigarette use. 124 (47.9%) had policies prohibiting staff and clients smoking together. Most California residential SUD programs allow outdoor smoking for staff and clients and few have adopted tobacco-free grounds policies. Given the reported interest in adopting tobacco-free policies, the high density of smokers in the SUD population, and the association of tobacco-free policies with lower client and staff smoking rates, state licensing and regulatory agencies, as well as county health departments, should work with SUD programs to adopt tobacco-free policies.
- Published
- 2020
14. Improving outcomes of childhood and young adult non-Hodgkin lymphoma: 25 years of research and collaboration within the framework of the European Intergroup for Childhood Non-Hodgkin Lymphoma
- Author
-
Beishuizen, Auke, Mellgren, Karin, Andrés, Mara, Auperin, Anne, Bacon, Chris M, Bomken, Simon, Burke, G A Amos, Burkhardt, Birgit, Brugieres, Laurence, Chiang, Alan K S, Damm-Welk, Christine, d'Amore, Emanuele, Horibe, Keizo, Kabickova, Edita, Khanam, Tasneem, Kontny, Udo, Klapper, Wolfram, Lamant, Laurence, Le Deley, Marie-Cecile, Loeffen, Jan, Macintyre, Elizabeth, Mann, Georg, Meyer-Wentrup, Friederike, Michgehl, Ulf, Minard-Colin, Veronique, Mussolin, Lara, Oschlies, Ilske, Patte, Catherine, Pillon, Marta, Reiter, Alfred, Rigaud, Charlotte, Ronceray, Leila, Salaverria, Itziar, Simonitsch-Klupp, Ingrid, Uyttebroeck, Anne, Verdu-Amoros, Jaime, Williams, Denise, Woessmann, Wilhelm, Wotherspoon, Andrew, Wrobel, Grazyna, Zimmermann, Martin, Attarbaschi, Andishe, and Turner, Suzanne D
- Published
- 2023
- Full Text
- View/download PDF
15. Delivery of a national prenatal exome sequencing service in England: a mixed methods study exploring healthcare professionals’ views and experiences
- Author
-
Peter, Michelle, primary, Mellis, Rhiannon, additional, McInnes-Dean, Hannah, additional, Daniel, Morgan, additional, Walton, Holly, additional, Fisher, Jane, additional, Leeson-Beevers, Kerry, additional, Allen, Stephanie, additional, Baple, Emma L., additional, Beleza-Meireles, Ana, additional, Bertoli, Marta, additional, Campbell, Jennifer, additional, Canham, Natalie, additional, Cilliers, Deirdre, additional, Cobben, Jan, additional, Eason, Jacqueline, additional, Harrison, Victoria, additional, Holder-Espinasse, Muriel, additional, Male, Alison, additional, Mansour, Sahar, additional, McEwan, Alec, additional, Park, Soo-Mi, additional, Smith, Audrey, additional, Stewart, Alison, additional, Tapon, Dagmar, additional, Vasudevan, Pradeep, additional, Williams, Denise, additional, Wu, Wing Han, additional, Chitty, Lyn S., additional, and Hill, Melissa, additional
- Published
- 2024
- Full Text
- View/download PDF
16. Recent cessation attempts and receipt of cessation services among a diverse primary care population – A mixed methods study
- Author
-
Gubner, Noah R, Williams, Denise D, Chen, Ellen, Silven, David, Tsoh, Janice Y, Guydish, Joseph, and Vijayaraghavan, Maya
- Subjects
Health Services and Systems ,Public Health ,Health Sciences ,Patient Safety ,Tobacco ,Tobacco Smoke and Health ,Health Disparities ,Substance Misuse ,Prevention ,Minority Health ,Behavioral and Social Science ,Clinical Research ,Health Services ,8.1 Organisation and delivery of services ,Health and social care services research ,3.1 Primary prevention interventions to modify behaviours or promote wellbeing ,Prevention of disease and conditions ,and promotion of well-being ,Respiratory ,Good Health and Well Being ,Public Health and Health Services ,Epidemiology ,Health services and systems ,Public health - Abstract
Smoking rates are high among low-income populations who seek care in safety-net clinics. While most safety-net clinics screen for cigarette smoking, there are substantial disparities in the delivery of smoking cessation counseling in these systems. We conducted a mixed method study between July 2016 and April 2017 to examine receipt of smoking cessation counseling and estimate recent cessation attempts among primary care patients in four safety-net clinics in San Francisco. We used the electronic health record (EHR) to examine receipt of cessation services and estimate cessation attempts, defined as transition from current to former smoking status during the 9-month study period. We conducted interviews with 10 staff and 16 patients to assess barriers to and facilitators of providing cessation services. Of the 3301 smokers identified via EHR, the majority (95.6%) received some type of cessation counseling during at least one clinical encounter, and 17.6% made a recent cessation attempt. Recent smoking cessation attempts and receipt of smoking cessation services differed significantly by clinic after adjusting for demographic factors. We identified patient and staff-level pre-disposing, reinforcing and enabling factors to increase delivery of cessation care, including increasing access to cessation medications and higher intensity counseling using a team-based approach. The EHR presents a useful tool to monitor patients' recent cessation attempts and access to cessation care. Combining EHR data with qualitative methods can help guide and streamline interventions to improve quality of cessation care and promote quit attempts among patients in safety-net settings.
- Published
- 2019
17. Smoking related outcomes before and after implementation of tobacco-free grounds in residential substance use disorder treatment programs
- Author
-
Gubner, Noah R, Williams, Denise D, Le, Thao, Garcia, Wayne, Vijayaraghavan, Maya, and Guydish, Joseph
- Subjects
Public Health ,Health Sciences ,Prevention ,Brain Disorders ,Behavioral and Social Science ,Tobacco Smoke and Health ,Substance Misuse ,Drug Abuse (NIDA only) ,Cancer ,Tobacco ,Clinical Research ,Lung Cancer ,Lung ,3.1 Primary prevention interventions to modify behaviours or promote wellbeing ,Cardiovascular ,Respiratory ,Good Health and Well Being ,Adult ,California ,Cross-Sectional Studies ,Female ,Humans ,Male ,Middle Aged ,Prevalence ,Smoking Cessation ,Substance Abuse Treatment Centers ,Substance-Related Disorders ,Surveys and Questionnaires ,Nicotiana ,Tobacco Products ,Tobacco Smoking ,Drug treatment ,Tobacco-free policy ,Taxation ,Tax ,Medical and Health Sciences ,Psychology and Cognitive Sciences ,Substance Abuse ,Biochemistry and cell biology ,Pharmacology and pharmaceutical sciences ,Epidemiology - Abstract
BackgroundThis study examined the impact of a tobacco-free grounds (TFG) policy and the California $2.00/pack tobacco tax increase on tobacco use among individuals in residential substance use disorder (SUD) treatment.MethodsWe conducted three cross-sectional surveys of clients enrolled in three residential SUD treatment programs. Wave 1 (Pre-TFG) included 190 clients, wave 2 (post-TFG and pre-tax increase) included 200 clients, and wave 3 (post-tax increase) included 201 clients. Demographic and tobacco-use characteristics were first compared between waves using bivariate comparisons. Regression models were used to compare each outcome with survey wave as the predictor, while adjusting for demographic characteristics and nesting of participants within programs.ResultsOdds of clients being current smokers was lower (AOR = 0.43, 95%CI = 0.30,0.60) after implementation of TFG compared to baseline. Adjusted mean ratio (AMR) for cigarettes per day was lower post-TFG compared to baseline (AMR = 0.70, CI = 0.59, 0.83). There were no differences, across waves, in tobacco-related knowledge, attitudes, or services received by program clients, or use of nicotine replacement therapy. Increased cigarette taxation was not associated with reductions in client smoking.ConclusionImplementation of a TFG policy was associated with a lower prevalence of client smoking among individuals in residential SUD treatment. Increased state cigarette excise taxes were not associated with a further reduction in client smoking in the presence of TFG policies, though this may have been confounded by relaxing of the TFG policy. SUD treatment programs should promote TFG policies and increase tobacco cessation services for clients.
- Published
- 2019
18. Tobacco Cessation Services in Addiction Treatment: What Do Clients Say?
- Author
-
Guydish, Joseph, Yip, Deborah, Le, Thao, Gubner, Noah R, Williams, Denise D, and Delucchi, Kevin L
- Subjects
Public Health ,Health Sciences ,Drug Abuse (NIDA only) ,Substance Misuse ,Behavioral and Social Science ,Brain Disorders ,Health Services ,Prevention ,Clinical Research ,Tobacco Smoke and Health ,Tobacco ,Prevention of disease and conditions ,and promotion of well-being ,3.1 Primary prevention interventions to modify behaviours or promote wellbeing ,Mental health ,Cancer ,Respiratory ,Good Health and Well Being ,Addiction Medicine ,Adult ,Counseling ,Female ,Humans ,Logistic Models ,Male ,Middle Aged ,Motivation ,Multivariate Analysis ,Patient Acceptance of Health Care ,Smoke-Free Policy ,Smoking ,Substance-Related Disorders ,Surveys and Questionnaires ,Tobacco Use Cessation ,United States ,Drug abuse ,Public health ,Tobacco cessation services ,addiction treatment ,psychopharmacology ,Public Health and Health Services ,Psychiatry ,Clinical sciences ,Health services and systems - Abstract
ObjectiveSpecialty addiction programs treat people who are addicted to alcohol, opioids, stimulants, and other drugs. This study identified the proportion of addiction program clients who received tobacco-related services and factors associated with receipt of such services.MethodsIn 2015 and 2016, clients (N=2,119) in 24 programs were surveyed for receipt of services aligning with three of the five As of tobacco cessation: ask, advise, assist. Multivariate analyses examined factors associated with receipt of each service.ResultsMost clients (76%) were asked about smoking. Among smokers (N=1,630), 53% were advised to quit, 41% received counseling, 26% received cessation medication, and 17% received counseling and medication. Clients were more likely to receive tobacco-related services if they wanted help quitting smoking or were enrolled in programs with tobacco-free grounds.ConclusionsThese correlational findings suggest that increasing client motivation to quit and implementing tobacco-free policies on the grounds of treatment centers may increase tobacco-related services in addiction treatment.
- Published
- 2019
19. Differences in tobacco use prevalence, behaviors, and cessation services by race/ethnicity: A survey of persons in addiction treatment
- Author
-
Pagano, Anna, Gubner, Noah R, Le, Thao, Yip, Deborah, Williams, Denise, Delucchi, Kevin, and Guydish, Joseph
- Subjects
Public Health ,Health Sciences ,Drug Abuse (NIDA only) ,Tobacco ,Behavioral and Social Science ,Cancer ,Tobacco Smoke and Health ,Substance Misuse ,Prevention ,Minority Health ,Brain Disorders ,Health Disparities ,Clinical Research ,Respiratory ,Stroke ,Good Health and Well Being ,Adult ,Black or African American ,Electronic Nicotine Delivery Systems ,Ethnicity ,Female ,Healthcare Disparities ,Hispanic or Latino ,Humans ,Male ,Middle Aged ,Multivariate Analysis ,Prevalence ,Regression Analysis ,Smokers ,Smoking ,Smoking Cessation ,Substance-Related Disorders ,Surveys and Questionnaires ,United States ,White People ,Young Adult ,Cessation ,Race ,Disparities ,Public Health and Health Services ,Psychology ,Substance Abuse ,Health services and systems ,Clinical and health psychology - Abstract
BackgroundDisparities in tobacco use prevalence, behaviors, and services have been identified among people of different racial and ethnic groups in the United States general population. Persons in addiction treatment have among the highest smoking prevalence of any population. However, little is known about racial and ethnic disparities in tobacco use prevalence, behaviors, and services among persons in addiction treatment.MethodsSurvey data were used from 1840 clients from 24 addiction treatment programs from the NIDA Clinical Trials Network. Multivariate regression analyses were conducted to assess associations between race/ethnicity (White, African American, Hispanic) and patterns of tobacco and other tobacco product use, as well as quitting behaviors and receipt of tobacco cessation services among current smokers (n = 1425) while in treatment.ResultsThere was no difference in cigarette smoking prevalence across racial/ethnic groups. In the multivariate models, Hispanics and African Americans, compared to Whites, were less likely to be daily smokers, use smokeless tobacco, or use e-cigarettes. African Americans and Hispanics reported more past-year quit attempts and higher use of menthol compared to Whites. Hispanics were more interested in quitting while in treatment than Whites. Contrary to expectations, African Americans reported receiving more tobacco cessation advice and services while in treatment than Whites.ConclusionsSome findings reflected broader population patterns (e.g., tobacco use behaviors, other tobacco product use), while others did not (e.g., no difference in tobacco use prevalence by race/ethnicity). The reasons for greater receipt of cessation services among African Americans are unclear. Findings indicate the need for continued engagement of African Americans and Hispanics in cessation services while in addiction treatment, and for addressing heavier tobacco use and lack of interest in cessation during treatment among White clients.
- Published
- 2018
20. Neuropsychiatric risk in children with intellectual disability of genetic origin: IMAGINE, a UK national cohort study
- Author
-
Wolstencroft, Jeanne, Wicks, Francesca, Srinivasan, Ramya, Erwood, Marie, Lafont, Amy, Timur, Husne, Ye, Zheng, Walker, Susan, Printzlau, Frida, Juj, Manoj, Davies, Sarah, Denyer, Hayley, Watkins, Alice, Kerry, Eleanor, Coscini, Nadia, Fatih, Nasrtullah, Lucock, Anna, Denaxas, Spiros, Mandy, William, Walker, Neil, Wallwork, Sarah, Dewhurst, Eleanor, Cuthbert, Andrew, Challenger, Aimee, Andrews, Sophie, Holmans, Peter, Bowen, Samantha, Bradley, Karen, Birch, Philippa, Tong, Molly, Lewis, Nicola, Ray, Sinead, Sopp, Matthew, Moss, Hayley, Wynn, Sarah, Searle, Beverley, Robertson, Lisa, Berg, Jonathan, Lampe, Anne, Joss, Shelagh, Brennan, Paul, Kraus, Alison, Lahiri, Nayana, Weber, Astrid, Rawson, Myfanwy, Johnson, Diana, Vasudevan, Pradeep, Harrison, Rachel, Williams, Denise, Maher, Eamonn, Kini, Usha, Van Dijk, Fleur, Clowes, Virginia, Gurasashvilli, Jana, Mansour, Sahar, Holder-Espinasse, Muriel, Watford, Amy, Rankin, Julia, Baralle, Diana, Procter, Annie, Ford, Tamsin, Baker, Kate, Chawner, Samuel, Hall, Jeremy, Van den Bree, Marianne B M, Owen, Michael J, Skuse, David, Raymond, F Lucy, Chawner, Samuel J R A, and van den Bree, Marianne B M
- Published
- 2022
- Full Text
- View/download PDF
21. Viral and Bacterial Infection Prevention Through Intentional Design
- Author
-
Harris, Debra, primary and Williams, Denise N., additional
- Published
- 2022
- Full Text
- View/download PDF
22. A Systematic Review of Conceptualizations and Operationalizations of Youth Polyvictimization.
- Author
-
Radtke, Spenser R., Wretman, Christopher J., Fraga Rizo, Cynthia, Franchino-Olsen, Hannabeth, Williams, Denise Yookong, Chen, Wan-Ting, and Macy, Rebecca J.
- Subjects
CHILD abuse & psychology ,JUVENILE delinquency ,CINAHL database ,CRIME victims ,SYSTEMATIC reviews ,MEDLINE ,MEDICAL research ,CONCEPTS ,ONLINE information services ,PSYCHOLOGY information storage & retrieval systems ,ADVERSE childhood experiences ,ADOLESCENCE - Abstract
Violence against youth is a global issue impacting millions each year. Increasingly, research has focused on studying those impacted by multiple forms of violence, or polyvictims. Evidence strongly suggests that polyvictimized youth tend to have worse physical and mental health outcomes than those who have experienced single forms of violence. Moreover, minoritized youth (i.e., racial and/or sexual minority youth, youth with disabilities) are more likely to experience polyvictimization, making this a social justice and equity concern. To date, there is no universal consensus on what exactly constitutes polyvictimization. This systematic review aims to examine the ways in which polyvictimization is being studied to inform both research and practice. As such, relevant databases were searched to amass the extant literature related to youth polyvictimization internationally. Empirical studies published since 2006 that focused on youth (under age 18) polyvictimization were included. After the review process, 264 studies met eligibility criteria, however 55 studies employed person-centered/finite mixture analyses and were removed for a separate review, resulting in 209 featured in the current systematic review. Results demonstrate that researchers are defining and operationalizing polyvictimization in different ways: (a) using individual victimization event counts; (b) employing domain-based counts; and (c) taking a "highest-victimized" percentage of their sample. The most used measurement tool was the Juvenile Victimization Questionnaire, though other validated tools and researcher-constructed questions were frequently utilized. Research on polyvictimization is burgeoning worldwide; however, this research is being conducted in disparate ways, making it difficult to compare findings and further advance the field. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
23. Strategies for Coping with Minority Stress among Queer Young Adults: Usage Frequency, Associations with Demographics, and Mental Health.
- Author
-
Xu, Yinuo, Hall, William J., Scott, McRae, Gao, Yutong, Chiang, Pin-Chen, Williams, Denise Yookong, Srivastava, Ankur, Ramon, Magdelene E., and Englert, Adam R.
- Published
- 2024
- Full Text
- View/download PDF
24. Menthol cigarette smoking among individuals in treatment for substance use disorders
- Author
-
Gubner, Noah R, Williams, Denise D, Pagano, Anna, Campbell, Barbara K, and Guydish, Joseph
- Subjects
Biological Psychology ,Clinical and Health Psychology ,Public Health ,Health Sciences ,Psychology ,Clinical Research ,Tobacco Smoke and Health ,Drug Abuse (NIDA only) ,Substance Misuse ,Tobacco ,Brain Disorders ,Prevention ,Cancer ,Cardiovascular ,Respiratory ,Good Health and Well Being ,Adult ,Black or African American ,Alcoholism ,Cigarette Smoking ,Educational Status ,Female ,Hispanic or Latino ,Humans ,Logistic Models ,Male ,Marijuana Abuse ,Menthol ,Middle Aged ,Motivation ,Prevalence ,Public Policy ,Smoking Cessation ,Substance-Related Disorders ,Tobacco Products ,United States ,White People ,Drug ,Alcohol ,Dependence ,Nicotine ,Mentholated ,Vulnerable ,Substance use disorder ,Public Health and Health Services ,Substance Abuse ,Public health ,Biological psychology ,Clinical and health psychology - Abstract
There are higher rates of menthol cigarette smoking within certain population subgroups. Limited research has examined menthol use among individuals in treatment for substance use disorders (SUD), a population with a high prevalence of cigarette smoking, poor smoking cessation outcomes, and high tobacco disease burden. Survey data were collected from 863 smokers sampled from 24 SUD treatment programs affiliated with the NIDA Clinical Trials Network (CTN) in the United States. Prevalence of menthol cigarette smoking was examined for the sample. Bivariate and multivariate analyses were used to examine demographic and tobacco use characteristics associated with menthol cigarette smoking. Overall, the prevalence of menthol smoking among individuals in SUD treatment was 53.3%. Smoking menthol versus non-menthol cigarettes was associated with being female (AOR=1.61, p=0.003), African American (AOR=7.89, p
- Published
- 2018
25. The Magic of Connection and Care: Experiences of Students of Color in Online Community College Classes
- Author
-
Maduli-Williams, Denise
- Subjects
Education ,Educational technology ,Community College ,Distance Education ,Online Learning ,Social Presence ,Students of Color - Abstract
Online education, also referred to as distance education, has been on a steady rise for over a decade, and California community colleges offer more online courses than any other public higher education institution. Although the success gap, as measured by course completion, between online and face-to-face learning is closing overall, online courses, specifically in California community colleges, continue to have lower success rates than the traditional in-person classes; furthermore, this disparity is exacerbated for students of color. One aspect that has been researched in this instructional modality has been the impact of social presence, or “the degree to which online participants feel connected to one another” (Whiteside, 2017, p. 4) in online courses. In addition, research specifically focused on community college students of color highlights the relational domain of teaching and learning as the foundation for success (Wood & Harris, 2015). This qualitative study sought to understand and amplify the experiences of students of color in online courses. This study utilized a dual-lens conceptual framework, which merged the Social Presence Model (Whiteside, 2015) with the Pyramid of Student Success for Men of Color in the Community Colleges (Wood and Harris, 2015). Together, they provided complementary lenses to examine how students of color experienced social presence in online courses, and how such experience related to their perceptions of feeling connected to the learning community and supported towards success in their online learning.Eleven study participants were interviewed in one-on-one semi-structured Zoom interviews. Thematic analysis revealed five main themes, including the magic of human connection, the importance of a warm welcome, the value of student-to-student interaction, the significance of instructor presence, and the clarity of content presentations. The findings give a window into the experiences of students of color in online courses, and implications include ways faculty and leaders can improve the online experiences for students of color and seek to close the gap between face-to-face and online learning.
- Published
- 2023
26. Prevalence of co-occurring conditions among youths receiving treatment with primary anxiety, ADHD, or depressive disorder diagnoses
- Author
-
Ware, Orrin D., primary, Zerden, Lisa D., additional, Duron, Jacquelynn F., additional, Xu, Yanfeng, additional, McCarthy, Lauren P., additional, Verbiest, Sarah, additional, Afkinich, Jenny, additional, Brown, Qiana, additional, Williams, Denise Yookong, additional, and Goings, Trenette, additional
- Published
- 2024
- Full Text
- View/download PDF
27. Which types of social support matter for Black sexual minority men coping with internalized homophobia? Findings from a mediation analysis
- Author
-
Dawes, Hayden C., primary, Eden, Tiffany M., additional, Hall, William J., additional, Srivastava, Ankur, additional, Williams, Denise Yookong, additional, and Matthews, Derrick D., additional
- Published
- 2024
- Full Text
- View/download PDF
28. The Postpandemic Nursing Workforce: Increasing Fill Rates and Reducing Workload Through a Generational Design of Workforce Layers
- Author
-
Rocchio, Betty Jo, Seys, Jill D., Williams, Denise L., Vancil, Barbara J., and McNett, Molly M.
- Published
- 2023
- Full Text
- View/download PDF
29. Implicit attitudes and implicit bias
- Author
-
Hall, William J., primary, Williams, Denise Yookong, additional, Dawes, Hayden C., additional, Adams, Leslie, additional, and Merino, Yesenia, additional
- Published
- 2022
- Full Text
- View/download PDF
30. Insights intoKIF11pathogenesis in Microcephaly-Lymphedema-Chorioretinopathy syndrome: a lymphatic perspective
- Author
-
Ogmen, Kazim, primary, Dobbins, Sara, additional, Martinez-Corral, Ines, additional, Behncke, Rose Yinghan, additional, Brown, Ryan C.S., additional, Ulferts, Sascha, additional, Hansmeier, Nils Rouven, additional, Sackey, Ege, additional, Alqahtani, Ahlam, additional, Karapouliou, Christina, additional, Grigoriadis, Dionysios, additional, Oberlin, Michael, additional, Williams, Denise, additional, Ekici, Arzu, additional, Karaer, Kadri, additional, Jeffery, Steve, additional, Mortimer, Peter, additional, Gordon, Kristiana, additional, Hogan, Benjamin M., additional, Mäkinen, Taija, additional, Hägerling, René, additional, Mansour, Sahar, additional, Martin-Almedina, Silvia, additional, and Ostergaard, Pia, additional
- Published
- 2023
- Full Text
- View/download PDF
31. Can We Apply TAM in Computer-Based Classes?
- Author
-
Williams, David and Williams, Denise
- Abstract
While students may struggle in any classroom and consequently require help beyond the schedule meeting time and place of the class, computer-based courses pose the additional hurdle of requiring ready access to hardware and software that may be unavailable or inconvenient for students outside of the classroom and its scheduled meeting time. This paper explores the application of TAM (Technology Acceptance Model) to computer-related classes in order to encourage students who need help to actually seek that help, thereby enhancing their likelihood of success. Increasing Ease of Use with respect to requesting and receiving needed help may consequently increase the likelihood that students will ask for and receive that needed help in their computer-based classes. Two anecdotal examples based on one of the author's practical experiences are provided to demonstrate how this may be possible.
- Published
- 2013
32. Recurrent heterozygous PAX6 missense variants cause severe bilateral microphthalmia via predictable effects on DNA–protein interaction
- Author
-
Williamson, Kathleen A., Hall, H. Nikki, Owen, Liusaidh J., Livesey, Benjamin J., Hanson, Isabel M., Adams, G. G. W., Bodek, Simon, Calvas, Patrick, Castle, Bruce, Clarke, Michael, Deng, Alexander T., Edery, Patrick, Fisher, Richard, Gillessen-Kaesbach, Gabriele, Heon, Elise, Hurst, Jane, Josifova, Dragana, Lorenz, Birgit, McKee, Shane, Meire, Francoise, Moore, Anthony T., Parker, Michael, Reiff, Charlotte M., Self, Jay, Tobias, Edward S., Verheij, Joke B. G. M., Willems, Marjolaine, Williams, Denise, van Heyningen, Veronica, Marsh, Joseph A., and FitzPatrick, David R.
- Published
- 2020
- Full Text
- View/download PDF
33. Recent cessation attempts and receipt of cessation services among a diverse primary care population – A mixed methods study
- Author
-
Gubner, Noah R., Williams, Denise D., Chen, Ellen, Silven, David, Tsoh, Janice Y., Guydish, Joseph, and Vijayaraghavan, Maya
- Published
- 2019
- Full Text
- View/download PDF
34. Smoking related outcomes before and after implementation of tobacco-free grounds in residential substance use disorder treatment programs
- Author
-
Gubner, Noah R., Williams, Denise D., Le, Thao, Garcia, Wayne, Vijayaraghavan, Maya, and Guydish, Joseph
- Published
- 2019
- Full Text
- View/download PDF
35. Latino entrepreneurs and social media adoption: personal and business social network platforms
- Author
-
Gavino, Monica C., Williams, Denise E., Jacobson, David, and Smith, Iris
- Published
- 2019
- Full Text
- View/download PDF
36. Microcephaly with or without chorioretinopathy, lymphoedema, or mental retardation (MCLMR): review of phenotype associated with KIF11 mutations
- Author
-
Jones, Gabriela E, Ostergaard, Pia, Moore, Anthony T, Connell, Fiona C, Williams, Denise, Quarrell, Oliver, Brady, Angela F, Spier, Isabel, Hazan, Filiz, Moldovan, Oana, Wieczorek, Dagmar, Mikat, Barbara, Petit, Florence, Coubes, Christine, Saul, Robert A, Brice, Glen, Gordon, Kristiana, Jeffery, Steve, Mortimer, Peter S, Vasudevan, Pradeep C, and Mansour, Sahar
- Subjects
Pediatric ,Clinical Research ,Genetics ,Brain Disorders ,Rare Diseases ,Intellectual and Developmental Disabilities (IDD) ,Aetiology ,2.1 Biological and endogenous factors ,Cohort Studies ,Family ,Female ,Humans ,Intellectual Disability ,Kinesins ,Lymphedema ,Male ,Microcephaly ,Mutation ,Penetrance ,Phenotype ,Retinal Diseases ,Clinical Sciences ,Genetics & Heredity - Abstract
Microcephaly with or without chorioretinopathy, lymphoedema, or mental retardation (MCLMR) (MIM No.152950) is a rare autosomal dominant condition for which a causative gene has recently been identified. Mutations in the kinesin family member 11 (KIF11) gene have now been described in 16 families worldwide. This is a review of the condition based on the clinical features of 37 individuals from 22 families. This report includes nine previously unreported families and additional information for some of those reported previously. The condition arose de novo in 8/20 families (40%). The parental results were not available for two probands. The mutations were varied and include missense, nonsense, frameshift, and splice site and are distributed evenly throughout the KIF11 gene. In our cohort, 86% had microcephaly, 78% had an ocular abnormality consistent with the diagnosis, 46% had lymphoedema, 73% had mild-moderate learning difficulties, 8% had epilepsy, and 8% had a cardiac anomaly. We identified three individuals with KIF11 mutations but no clinical features of MCLMR demonstrating reduced penetrance. The variable expression of the phenotype and the presence of mildly affected individuals indicates that the prevalence may be higher than expected, and we would therefore recommend a low threshold for genetic testing.
- Published
- 2014
37. Prenatal diagnosis of PORCN‐related developmental syndrome in a fetus: A novel phenotype
- Author
-
Kilby, Mark D., primary, Castleman, James, additional, Allen, Stephanie, additional, Doyle, Samantha, additional, and Williams, Denise K., additional
- Published
- 2023
- Full Text
- View/download PDF
38. Experiences of Queer People of Color in Mental Health Care and Substance Use Treatment: A Systematic Review
- Author
-
Dawes, Hayden Cedric, primary, Williams, Denise Yookong, additional, Klein, LB, additional, Forte, Alexandria B., additional, Gibbs, Daniel J., additional, Wood, Bennett, additional, Hirst, Luke E., additional, and Hall, William James, additional
- Published
- 2023
- Full Text
- View/download PDF
39. Menthol cigarette smoking among individuals in treatment for substance use disorders
- Author
-
Gubner, Noah R., Williams, Denise D., Pagano, Anna, Campbell, Barbara K., and Guydish, Joseph
- Published
- 2018
- Full Text
- View/download PDF
40. Translating Knowledge Management Visions into Strategies
- Author
-
Monique Ceruti, Angel Williams, Denise Bedford and Monique Ceruti, Angel Williams, Denise Bedford
- Published
- 2019
41. Carbon Dots: A Modular Activity to Teach Fluorescence and Nanotechnology at Multiple Levels
- Author
-
Pham, Susan N., Kuether, Joshua E., Gallagher, Miranda J., Hernandez, Rodrigo Tapia, Williams, Denise N., Zhi, Bo, Mensch, Arielle C., Hamers, Robert J., Rosenweig, Zeev, Fairbrother, Howard, Krause, Miriam O. P., Feng, Z. Vivian, and Haynes, Christy L.
- Abstract
In recent years, nanomaterials have entered our daily lives via consumer products; thus, it has become increasingly important to implement activities to introduce these novel materials into chemistry curricula. Here we introduce a newly developed fluorescent nanomaterial, carbon dots, as a more environmentally friendly alternative to heavy-metal semiconductor quantum dots to be used as a model nanomaterial for experiments at multiple educational levels ranging from high school to upper-division college laboratories. These dots, which are polymeric in nature, can be made from a variety of carbon precursors and a cross-linker such as ethylenediamine. The synthesis, which involves heating in a conventional microwave, is quick and straightforward and can be carried out in typical high school chemistry laboratories. The resulting solution is fluorescent without further purification. To increase the complexity for entry-level college students, absorption and emission spectra of the carbon dot solution can be collected as an introduction to spectroscopy. In more advanced undergraduate lab courses, the quantum yield can be determined with a standard reference fluorescent material such as quinine sulfate. Atomic force microscopy or transmission electron microscopy images can also be collected to illustrate the morphology of these particles where such specialty instruments are accessible.
- Published
- 2017
- Full Text
- View/download PDF
42. Molecular autopsy by trio exome sequencing (ES) and postmortem examination in fetuses and neonates with prenatally identified structural anomalies
- Author
-
Quinlan-Jones, Elizabeth, Lord, Jenny, Williams, Denise, Hamilton, Sue, Marton, Tamas, Eberhardt, Ruth Y., Rinck, Gabriele, Prigmore, Elena, Keelagher, Rebecca, McMullan, Dominic J., Maher, Eamonn R., Hurles, Matthew E., and Kilby, Mark D.
- Published
- 2019
- Full Text
- View/download PDF
43. THE VASCULAR FLORA OF THE LAGUNA DE ALEGRÍA, A NATIONAL MONUMENT IN THE CRATER OF TECAPA VOLCANO, EL SALVADOR
- Author
-
Williams, Denise, Herrera, Rudys W, Linares, José L, and BioStor
- Published
- 2002
44. Relationships between internalized stigma and depression and suicide risk among queer youth in the United States: a systematic review and meta-analysis
- Author
-
Williams, Denise Yookong, primary, Hall, William J., additional, Dawes, Hayden C., additional, Srivastava, Ankur, additional, Radtke, Spenser R., additional, Ramon, Magdelene, additional, Bouchard, D., additional, Chen, Wan-Ting, additional, and Goldbach, Jeremy T., additional
- Published
- 2023
- Full Text
- View/download PDF
45. Prenatal diagnosis of CLCN4‐related neurodevelopmental disorder in fetuses with congenital brain anomalies
- Author
-
Lam, Zena, primary, Wall, Elizabeth, additional, Ryan, Gavin, additional, Barber, Richard, additional, Kilby, Mark D., additional, and Williams, Denise K., additional
- Published
- 2023
- Full Text
- View/download PDF
46. Inclusion in the workplace: an integrative literature review
- Author
-
Nguyen, Loi Anh, primary, Evan, Rebecca, additional, Chaudhuri, Sanghamitra, additional, Hagen, Marcia, additional, and Williams, Denise, additional
- Published
- 2023
- Full Text
- View/download PDF
47. Mirror Work: Impacting Culturally Responsive Practices Through Racial Literacy, Cultural Competence, and Professional Learning
- Author
-
Williams, Denise Louise and Williams, Denise Louise
- Abstract
The inconsistent roll-out of New York State’s Culturally Responsive Sustaining Education (CRSE) Framework left principals in a Bronx district with insufficient capacity to fully leverage the framework. Taking an Improvement Science approach, the aim of this mixed methods case study research was to deepen the racial literacy and cultural competence of principals in service of implementing shared and inclusive curricula aligned with the Framework. The study used three change ideas implemented in a single six-month Plan-Do-Study-Act cycle: 1) building healthy racial identities through conversations about race, 2) building cultural competence through culturally responsive lessons, and 3) implementing district professional learning on Culturally Responsive School Leadership (CRSL). The study addressed the lack of instrumentation to measure racial literacy and cultural competence by creating two innovative instruments, available for other scholars, using evidence-based frameworks in the research literature: the CRSE Self-Reflection Survey and the Cultural Competence and Racial Literacy Reflection Survey. The study found that a collectivist approach to building the racial literacy of school leaders increased principals’ critical self-awareness and fostered the use of common language to engage in difficult conversations about race. Designing opportunities for leaders to authentically connect to the community deepened their understanding of how school policies must serve as a catalyst to affirm the identities of students and their families. Using teams as a shared site of learning, providing opportunities to critically self-reflect, and providing job-embedded support empowered principals to immerse themselves in the vision of the Framework. The researcher advocates that equity is integral, not optional.
- Published
- 2023
48. Immunoregulatory pathways in murine cutaneous leishmaniasis
- Author
-
Williams, Denise M.
- Published
- 1993
49. Prenatal Exome Sequencing Analysis in Fetal Structural Anomalies Detected by Ultrasonography (PAGE): A Cohort Study
- Author
-
Lord, Jenny, McMullan, Dominic J., Eberhardt, Ruth Y., Rinck, Gabriele, Hamilton, Susan J., Quinlan-Jones, Elizabeth, Prigmore, Elena, Keelagher, Rebecca, Best, Sunayna K., Carey, Georgina K., Mellis, Rhiannon, Robart, Sarah, Berry, Ian R., Chandler, Kate E., Cilliers, Deirdre, Cresswell, Lara, Edwards, Sandra L., Gardiner, Carol, Henderson, Alex, Holden, Simon T., Homfray, Tessa, Lester, Tracy, Lewis, Rebecca A., Newbury-Ecob, Ruth, Prescott, Katrina, Quarrell, Oliver W., Ramsden, Simon C., Roberts, Eileen, Tapon, Dagmar, Tooley, Madeleine J., Vasudevan, Pradeep C., Weber, Astrid P., Wellesley, Diana G., Westwood, Paul, White, Helen, Parker, Michael, Williams, Denise, Jenkins, Lucy, Scott, Richard H., Kilby, Mark D., Chitty, Lyn S., Hurles, Matthew E., and Maher, Eamonn R.
- Published
- 2019
- Full Text
- View/download PDF
50. Finding the Supervision Key of Therapists’ Progress
- Author
-
Kadieva, Violeta D., primary and Williams, Denise N., additional
- Published
- 2022
- Full Text
- View/download PDF
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.