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20 results on '"William W. Zeller"'

1. Liquid versus solid penicillin in oil and wax; the effect of particle size and type of penicillin

Author

Harold L. Hirsh, Jay A. Robinson, Velma L. Chandler, William W. Zeller, Harry F. Dowling, Henry Welch, and Monroe J. Romansky

Subjects
Wax, Chromatography, medicine.drug_class, business.industry, Sodium, Potassium, Antibiotics, chemistry.chemical_element, Penicillins, Beeswax, Microbiology, Penicillin, chemistry, visual_art, medicine, visual_art.visual_art_medium, Particle size, Absorption (chemistry), Particle Size, business, medicine.drug
Abstract

The incorporation of penicillin in oil and beeswax has been found to be a satisfactory method of prolonging the absorption of penicillin. Romansky and Rittman, 1 the originators of the method, showed that after the injection of 300,000 units of amorphous calcium penicillin in oil and wax 70 per cent of the patients so treated had demonstrable blood concentrations of penicillin for twenty-four hours. Several modifications of the original preparation have now been made and utilized clinically. 2 Crystalline sodium and potassium as well as the amorphous calcium penicillin were found suitable for use in the mixture. Furthermore, certain preparations were devised which were fluid at room temperature and did not require heating before injection. The liquid preparations of penicillin in oil and wax, which are fluid at room temperature (below 43.3 C. or 110 F.), 3 are now available commercially and are identical in composition with the original viscid

Published
2010

3. Meningitis due to pasteurella other than pasteurella tularensis and pasteurella pestis

Author

Mark H. Lepper and William W. Zeller

Subjects
Pasteurella tularensis, biology, Yersinia pestis, business.industry, medicine.drug_class, Antibiotics, General Medicine, medicine.disease, biology.organism_classification, Virology, Microbiology, Genus Pasteurella, Penicillin, Sulfadiazine, Pasteurella pestis, otorhinolaryngologic diseases, medicine, Humans, Meningitis, Pasteurella, Francisella tularensis, business, medicine.drug
Abstract

Two new cases of meningitis attributable to microorganisms of the genus pasteurella other than Past. tularensis and Past. pestis are reported herein. Although complete bacteriologic identification of the species of the causative microorganism in each case was impossible, the probability is strong that it was Past. multocida. In one case sulfadiazine was administered; in the other, both sulfadiazine and massive doses of penicillin.

Published
1950

6. A method for determining the size and relative weight of penicillin particles and its importance in preparing adequate preparations of liquid penicillin in oil and wax††A cooperative study by members of the Division of Penicillin Control and Immunology, Food and Drug Administration, Federal Security Agency; Gallinger Municipal Hospital; the Department of Medicine, George Washington University School of Medicine; and the Antibiotic Laboratory, Walter Reed General Hospital, Washington, D. C.*

Author

Harold L. Hirsh, Monroe J. Romansky, Henry Welch, Harry F. Dowling, Velma L. Chandler, Jay A. Robinson, and William W. Zeller

Subjects
Penicillin, Wax, Chromatography, Chemistry, visual_art, polycyclic compounds, visual_art.visual_art_medium, medicine, Relative weight, Body weight, medicine.drug
Abstract

The efficiency of penicillin in oil and wax is influenced by the size and relative weight of penicillin particles. A method is described by which sizes and relative weights of penicillin particles may be determined. The results by the method described are correlated with blood levels obtained following injections of penicillin in oil and wax.

Published
1948

7. The new morality re-evaluated: a psychiatrist's point of view

Author

William W. Zeller

Subjects
Psychiatry, medicine.medical_specialty, Psychoanalysis, Point (typography), Adolescent, Social Values, business.industry, media_common.quotation_subject, Sexual Behavior, Culture, Decision Making, Coitus, Obstetrics and Gynecology, Morality, Morals, Personality Development, Psychosexual Development, Medicine, Humans, Family, Women, business, Attitude to Health, media_common
Published
1974

8. Gonococcal arthritis; a study of 202 patients treated with penicillin, sulfonamides or fever therapy

Author

Jay A. Robinson, Harold L. Hirsh, Harry F. Dowling, and William W. Zeller

Subjects
medicine.medical_specialty, medicine.drug_class, Gonococcal arthritis, Antibiotics, Arthritis, Penicillins, Typhoid fever, Fever therapy, Gonorrhea, Pharmacotherapy, Sulfanilamide, Internal medicine, Sulfanilamides, Internal Medicine, medicine, Humans, Sulfonamides, business.industry, General Medicine, Hyperthermia, Induced, medicine.disease, Surgery, Penicillin, Syphilis, business, medicine.drug
Abstract

Excerpt Prior to March, 1932, only symptomatic measures were available for the treatment of gonococcal arthritis. At that time, it was observed during a course of fever therapy for syphilis that th...

Published
1949

9. The effect of caronamide on the blood concentration of penicillin following oral and intramuscular administration of penicillin

Author

Harold L. Hirsh, Harry F. Dowling, William W. Zeller, Jay A. Robinson, and Mark H. Lepper

Subjects
Sulfonamides, medicine.drug_class, business.industry, Antibiotics, Renal function, General Medicine, Penicillins, Pharmacology, Penicillin, Sulfanilamide, Blood concentration, Oral administration, Anesthesia, Toxicity, Sulfanilamides, Internal Medicine, medicine, Vomiting, Humans, medicine.symptom, Intramuscular injection, business, medicine.drug
Abstract

Excerpt One of the greatest problems in the clinical use of penicillin has been the maintenance of adequate plasma concentrations in spite of the rapid rate at which the antibiotic is excreted by t...

Published
1949

11. Use of chlorpromazine and reserpine in the treatment of emotional disorders

Author

Paul N. Graffagnino, Chester F. Cullen, H. Jerome Rietman, and William W. Zeller

Subjects
medicine.medical_specialty, Psychosis, Reserpine, business.industry, Chlorpromazine, Mood Disorders, Mental Disorders, Placebo, medicine.disease, behavioral disciplines and activities, Secologanin Tryptamine Alkaloids, Schizophrenic reaction, Psychotherapy, Anesthesia, mental disorders, Etiology, Medicine, business, Psychiatry, Electroconvulsive Therapy, medicine.drug
Abstract

• Patients receiving uninterrupted medication with either chlorpromazine or reserpine constituted a control group for comparison with a group in whom the medication was interrupted by one month of medication with a placebo. Both chlorpromazine and reserpine caused significant behavioral and affective improvement, especially in the manic phase of manic-depressive psychosis, in agitated states, and in schizophrenic reaction. The drugs differed in their side-effects, but they are valuable to the psychiatrist in controlling destructive, disturbed behavior regardless of the underlying etiology.

Published
1956

12. A PRACTICAL HANDBOOK OF PSYCHIATRY

Author

William W Zeller

Subjects
Psychiatry and Mental health, medicine.medical_specialty, medicine, Psychology, Psychiatry
Published
1975

14. THE WILL TO BE HUMAN

Author

William W Zeller

Subjects
Psychiatry and Mental health
Published
1973

16. Psychiatry and the Human Condition

Author

William W. Zeller

Subjects
Psychiatry and Mental health, medicine.medical_specialty, medicine, Human condition, Psychiatry, Psychology
Published
1977

20. A novel telemedicine protocol improved outcomes for high-risk patients with type 1 diabetes: A 3-month quality improvement project during the COVID-19 pandemic.

Author

Zeller WP Jr, DeGraff R, and Zeller W

Abstract

Our endocrinology practice needed to protect its highest-risk patients with type 1 diabetes (T1D) during the COVID-19 pandemic. To do so, we needed to identify these patients and develop a protocol to keep them out of the hospital (to limit risk of infection and conserve medical resources), and do so without in-person visits. So we used our peer-reviewed software, Diabetes Reporting, to identify 87 patients whose glucose management indicator (GMI) scores were over 9%. The GMI is a method for estimating the laboratory A1C using the patient's actual blood glucose measurements over the past 90 days. A GMI (or A1C) over 9% indicates a heightened risk of diabetic ketoacidosis (DKA) and, possibly, a slightly higher risk of severe hypoglycemia (SH), the two most common acute complications leading patients with T1D to be hospitalized. We contacted these 87 at-risk patients and enrolled them in a quality improvement project. This project consisted of additional online meetings with their doctors as well as weekly reports generated by Diabetes Reporting for three months, between March 28, 2020 and June 28, 2020. We hypothesized that this heightened communication would reduce the incidence of DKA and SH among the participants by reducing their GMI. As a comparison group, we used data from the T1D Exchange, which showed that, among patients with an A1C over 9%, 6.7% were hospitalized for DKA and 7% experienced SH leading to loss of consciousness in a three-month period. This led us to predict 6 incidences of DKA and 6 incidences of SH among our 87 participants during the three-month period. Instead, we saw 2 incidences of DKA and 1 incidence of SH. Moreover, the mean GMI of our participants dropped from 9.91% to 9.25%, a clinically-significant 0.66% improvement, which supports the conclusion that our protocol helped avoid acute complications among a cohort of at-risk patients with T1D by improving glycemic control during a time when we were limited to largely online care. This telemedicine protocol merits further research for its potential to improve and lower costs of care for patients with T1D, particularly for those at higher risk for acute complications., Competing Interests: ● The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: The authors have ownership interests in Diabetes Reporting, the software they developed and used as part of the intervention in this quality improvement project., (© 2021 Published by Elsevier Inc.)

Published
2021
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