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2. Minimally Invasive Surgery for High-Risk Subpopulations: Transaxillary Access Enhances Survival in Adipose Patients.

Author

Wilbring, M., Arzt, S., Petrov, A., Alexiou, K., Matschke, K., and Kappert, U.

Subjects
*MINIMALLY invasive procedures, *AORTIC valve transplantation, *PERIPHERAL vascular diseases, *CHRONIC kidney failure
Abstract

This article, published in the journal Thoracic & Cardiovascular Surgeon, examines the outcomes of minimally invasive cardiac surgery (MICS) in adipose patients compared to a sternotomy cohort. The study analyzed a cohort of 3,431 patients undergoing elective aortic valve replacement (AVR), with 200 patients with a body-mass-index (BMI) >30 g/m2 undergoing MICS-AVR using transaxillary access as the treatment group. A control group of isolated AVRs by full sternotomy was generated through propensity-matching. The results showed that MICS-AVR demonstrated better survival and less postoperative morbidity in adipose patients compared to the sternotomy-control group. [Extracted from the article]

Published
2024
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3. Transaxillary Access for Minimally Invasive Surgery for Benign Primary Cardiac Tumors.

Author

Waghefi, Taghizadeh-, ŽIvković, I., Petrov, A., Alexiou, K., Kappert, U., Matschke, K., and Wilbring, M.

Subjects
MINIMALLY invasive procedures, TUMORS, HYPERHIDROSIS
Abstract

This article discusses the use of transaxillary access for minimally invasive surgery (MICS) in the treatment of benign primary cardiac tumors, specifically myxomas. The study compares the outcomes of patients who underwent MICS with those who underwent conventional surgery using full sternotomy (FS). The results show that transaxillary access is a safe and efficient alternative to FS, with similar EuroSCORE II scores and skin-to-skin times. Nondisabling strokes were observed in both groups, and wound healing complications were more frequent in the FS group. Overall, transaxillary access shows promise in reducing complications in cardiac tumor surgery. [Extracted from the article]

Published
2024
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4. Mesenteric Ischemia after Cardiac Surgery—An Inevitable Fate?

Author

Petrov, A., Hotz, F., Taghizadeh-Waghefi, A., Georgi, C., Matschke, K., and Wilbring, M.

Subjects
CARDIAC surgery, COMPUTED tomography
Abstract

This article discusses the occurrence of mesenteric ischemia (Me-Is) after cardiac surgery, which is not well-documented in current literature. The study analyzes data from 22,590 patients who underwent cardiac surgery between 2009 and 2019, with 106 (0.47%) developing Me-Is postoperatively. The study finds that the prognosis for Me-Is following cardiac surgery is poor, regardless of diagnostic or treatment patterns. The article highlights the importance of early detection and intervention for better outcomes. [Extracted from the article]

Published
2024
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5. The Earlier the Better? When to Implant Pacemaker after Aortic Valve Replacement.

Author

Madej, T., Majer, M., Wilbring, M., Matschke, K., Knaut, M., and Taghizadeh-Waghefi, A.

Subjects
AORTIC valve transplantation, CARDIAC pacemakers, CARDIAC pacing, HEART valve prosthesis implantation
Abstract

This article discusses the optimal timing for implanting a permanent pacemaker (PM) after aortic valve replacement (AVR). Traditionally, a waiting period of 5-7 days was recommended, but recent guidelines suggest earlier implantation under certain circumstances. The study evaluated patients who received AVR between January 2019 and December 2021 and found that 12.4% required temporary or permanent pacing. The incidence of permanent PM implantation was 11.3%, with a median duration of 8 days. Early PM implantation was associated with a higher complication rate but a shorter hospital stay. [Extracted from the article]

Published
2024
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28. Untersuchungen zur Gefäßfunktion der humanen A. mammaria interna nach Kaltlagerung in Kombination mit antimikrobieller Dekontamination

Author

Deußen, A., Wilbring, M., Technische Universität Dresden, Vogel, Franziska, Deußen, A., Wilbring, M., Technische Universität Dresden, and Vogel, Franziska

Abstract

Ziel dieser Arbeit war die Verbesserung der Qualität und Vitalität von Gefäßtransplantaten bei Kaltlagerung. Optimiert wurden antimikrobiell wirksame Gefäßprotektionslösungen unter der Berücksichtigung der strengen Auflagen des Arzneimittelgesetzes (AMG). Für die umfangreichen Untersuchungen sind gesetzliche Mindestzeiten von bis zu einer Woche festgelegt. Für die antimikrobielle Dekontamination der Grafts wird ein Zeitraum zwischen 20 und 48 Stunden angegeben. In dieser Studie wurde die bereits sehr erfolgreich getestete Protektionslösung TiProtec® für Kaltlagerungsbedingungen genutzt. Zur Evaluierung der Gefäßfunktionen wurde die humane A. mammaria interna verwendet. Bei den Funktionsmessungen wurden die Wandspannungsentwicklung durch die rezeptorabhängige und rezeptorunabhängige Konstriktion sowie die endothelabhängige und die endothelunabhängige Vasodilatation evaluiert. Getestet wurden kurze Lagerungszeiten von 2 bis 48 Stunden sowie lange Lagerungszeiten von 96 Stunden bis zu einer Woche. Des Weiteren wurde überprüft, ob die Lagerung der Arteriensegmente für 48 Stunden in einer speziellen Lagerungslösung mit anschließender Umlagerung für weitere fünf Tage in TiProtec® eine Verbesserung der Funktionalität bewirkte. Untersucht wurden vier antimikrobielle Dekontaminationslösungen. Neben der Vergleichsgruppe mit TiProtec®-Lösung ohne Zusatz, wurden als Zusätze die Antibiotikamixtur 1 (Gentamicin, Clindamycin, Flucloxacillin, Metronidazol, Fluconazol und Itraconazol), Antibiotikamixtur 2 ( Gentamicin, Clindamycin, Metronidazol und Fluconazol) und das Antiseptikum Taurolidin in den Konzentrationen 0,5% und 0,002% verwendet.

Published
2018

42. Treatment of Failing Mitral Bioprostheses and Repair using Annuloplasty Rings: Transcatheter Mitral Valve Implantation versus Re-Operative Surgery

Author

Silaschi, M., additional, Westhofen, S., additional, Seiffert, M., additional, Bicer, D., additional, Schofer, N., additional, Wilbring, M., additional, Deuschl, F., additional, Aldalati, O., additional, Blankenberg, S., additional, Charitos, E., additional, MacCarthy, P., additional, Reichenspurner, H., additional, Schäfer, U., additional, Treede, H., additional, Conradi, L., additional, and Wendler, O., additional

Published
2017
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47. Transcatheter aortic valve implantation in failed bioprosthetic surgical valves

Author

Dvir, D., Webb, J.G., Bleiziffer, S., Pasic, M., Waksman, R., Kodali, S., Barbanti, M., Latib, A., Schaefer, U., Rodes-Cabau, J., Treede, H., Piazza, N., Hildick-Smith, D., Himbert, D., Walther, T., Hengstenberg, C., Nissen, H., Bekeredjian, R., Presbitero, P., Ferrari, E., Segev, A., Weger, A. de, Windecker, S., Moat, N.E., Napodano, M., Wilbring, M., Cerillo, A.G., Brecker, S., Tchetche, D., Lefevre, T., Marco, F. de, Fiorina, C., Petronio, A.S., Teles, R.C., Testa, L., Laborde, J.C., Leon, M.B., Kornowski, R., Valve In Valve Int Data Registry, and Valve-in-Valve International Data Registry Investigators

Subjects
Aortic valve, Adult, Male, medicine.medical_specialty, Cardiac Catheterization, medicine.medical_treatment, Aortic Valve Insufficiency, Prosthesis Design, Interquartile range, Internal medicine, Aged, Aged, 80 and over, Aortic Valve, Aortic Valve Stenosis, Female, Heart Valve Prosthesis Implantation, Humans, Middle Aged, Prosthesis Failure, Registries, Survival Analysis, Treatment Outcome, Bioprosthesis, Medicine (all), medicine, 80 and over, Survival rate, Survival analysis, Cardiac catheterization, business.industry, Hazard ratio, Aortic Valve/surgery, Aortic Valve Insufficiency/surgery, Aortic Valve Stenosis/surgery, Heart Valve Prosthesis Implantation/methods, General Medicine, medicine.disease, Surgery, Stenosis, medicine.anatomical_structure, Aortic valve stenosis, Cardiology, business
Abstract

IMPORTANCE: Owing to a considerable shift toward bioprosthesis implantation rather than mechanical valves, it is expected that patients will increasingly present with degenerated bioprostheses in the next few years. Transcatheter aortic valve-in-valve implantation is a less invasive approach for patients with structural valve deterioration; however, a comprehensive evaluation of survival after the procedure has not yet been performed. OBJECTIVE: To determine the survival of patients after transcatheter valve-in-valve implantation inside failed surgical bioprosthetic valves. DESIGN, SETTING, AND PARTICIPANTS: Correlates for survival were evaluated using a multinational valve-in-valve registry that included 459 patients with degenerated bioprosthetic valves undergoing valve-in-valve implantation between 2007 and May 2013 in 55 centers (mean age, 77.6 [SD, 9.8] years; 56% men; median Society of Thoracic Surgeons mortality prediction score, 9.8% [interquartile range, 7.7%-16%]). Surgical valves were classified as small (≤21 mm; 29.7%), intermediate (>21 and

Published
2014

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