24 results on '"Wigglesworth, Mark J"'
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2. A Perspective on Synthetic Biology in Drug Discovery and Development—Current Impact and Future Opportunities
3. Genetically Encoded Whole Cell Biosensor for Drug Discovery of HIF-1 Interaction Inhibitors
4. Screening β-Arrestin Recruitment for the Identification of Natural Ligands for Orphan G-Protein–Coupled Receptors
5. High affinity binding of the peptide agonist TIP-39 to the parathyroid hormone 2 (PTH2) receptor requires the hydroxyl group of Tyr-318 on transmembrane helix 5
6. A salt bridge between Arg-20 on parathyroid hormone (PTH) and Asp-137 on the PTH1 receptor is essential for full affinity
7. Receptor component protein, an endogenous allosteric modulator of family B G protein coupled receptors
8. Receptor component protein, an endogenous allosteric modulator of family B G protein coupled receptors
9. High affinity binding of the peptide agonist TIP-39 to the parathyroid hormone 2 (PTH 2 ) receptor requires the hydroxyl group of Tyr-318 on transmembrane helix 5
10. Increasing the delivery of next generation therapeutics from high throughput screening libraries
11. Novel imidazobenzazepine derivatives as dual H 1/5-HT 2A antagonists for the treatment of sleep disorders
12. Non-peptidic antagonists of the CGRP receptor, BIBN4096BS and MK-0974, interact with the calcitonin receptor-like receptor via methionine-42 and RAMP1 via tryptophan-74
13. ChemInform Abstract: Novel Imidazobenzazepine Derivatives as Dual H1/5‐HT2A Antagonists for the Treatment of Sleep Disorders.
14. Novel Spirotetracyclic Zwitterionic Dual H1/5-HT2A Receptor Antagonists for the Treatment of Sleep Disorders
15. Towards the Discovery of New Hypnotic Agents: Synthesis and Preliminary Pharmacological Evaluation of a Novel Class of Dibenzo[a,d]cycloheptene Derivatives
16. Novel imidazobenzazepine derivatives as dual H1/5-HT2A antagonists for the treatment of sleep disorders
17. Non-peptidic antagonists of the CGRP receptor, BIBN4096BS and MK-0974, interact with the calcitonin receptor-like receptor via methionine-42 and RAMP1 via tryptophan-74
18. The Discovery of a Selective, Small Molecule Agonist for the Mas-Related Gene X1 Receptor
19. Ligand-Receptor Interactions at the Parathyroid Hormone Receptors: Subtype Binding Selectivity Is Mediated via an Interaction between Residue 23 on the Ligand and Residue 41 on the Receptor
20. The Orphan G Protein-coupled Receptors GPR41 and GPR43 Are Activated by Propionate and Other Short Chain Carboxylic Acids
21. Towards the Discovery of New Hypnotic Agents: Synthesis and Preliminary Pharmacological Evaluation of a Novel Class of Dibenzo[ a, d]cycloheptene Derivatives.
22. Receptor component protein, an endogenous allosteric modulator of family B G protein coupled receptors
23. ChemInform Abstract: Novel Imidazobenzazepine Derivatives as Dual H.
24. Novel imidazobenzazepine derivatives as dual H1/5-HT2A antagonists for the treatment of sleep disorders
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