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Your search keyword '"Wiese, Andrea"' showing total 11 results
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11 results on '"Wiese, Andrea"'

1. Safety, usability, and performance of a wireless left atrial pressure monitoring system in patients with heart failure: the VECTOR-HF trial

Author

D'Amario, Domenico, Meerkin, David, Restivo, Attilio, Ince, Hüseyin, Sievert, Horst, Wiese, Andrea, Schaefer, Ulrich, Trani, Carlo, Bayes-Genis, Antoni, Leyva, Francisco, Whinnett, Zachary I, Di Mario, Carlo, Jonas, Michael, Manhal, Habib, Amat-Santos, Ignacio J, Del Trigo, Maria, Gal, Tuvia Ben, Ben Avraham, Binyamin, Hasin, Tal, Feickert, Sebastian, D'Ancona, Giuseppe, Altisent, Omar Abdul-Jawad, Koren, Oran, Caspi, Oren, Abraham, William T, Crea, Filippo, Anker, Stefan D, Kornowski, Ran, Perl, Leor, Trani, Carlo (ORCID:0000-0001-9777-013X), Crea, Filippo (ORCID:0000-0001-9404-8846), D'Amario, Domenico, Meerkin, David, Restivo, Attilio, Ince, Hüseyin, Sievert, Horst, Wiese, Andrea, Schaefer, Ulrich, Trani, Carlo, Bayes-Genis, Antoni, Leyva, Francisco, Whinnett, Zachary I, Di Mario, Carlo, Jonas, Michael, Manhal, Habib, Amat-Santos, Ignacio J, Del Trigo, Maria, Gal, Tuvia Ben, Ben Avraham, Binyamin, Hasin, Tal, Feickert, Sebastian, D'Ancona, Giuseppe, Altisent, Omar Abdul-Jawad, Koren, Oran, Caspi, Oren, Abraham, William T, Crea, Filippo, Anker, Stefan D, Kornowski, Ran, Perl, Leor, Trani, Carlo (ORCID:0000-0001-9777-013X), and Crea, Filippo (ORCID:0000-0001-9404-8846)

Abstract

Aims: In heart failure (HF), implantable hemodynamic monitoring devices have been shown to optimize therapy, anticipating clinical decompensation and preventing hospitalization. Direct left-sided hemodynamic sensors offer theoretical benefits beyond pulmonary artery pressure (PAP) monitoring systems. We evaluated the safety, usability, and performance of a novel left atrial pressure (LAP) monitoring system in HF patients. Methods and results: The VECTOR-HF study(NCT03775161) was a first-in-human, prospective, multicenter, single-arm, clinical trial enrolling 30 patients with HF. The device consisted of an interatrial positioned leadless sensor, able to transmit LAP data wirelessly. After three months, a right heart catheterization (RHC) was performed to correlate mean pulmonary capillary wedge pressure (PCWP) with simultaneous mean LAP obtained from the device. Remote LAP measurements were then used to guide patient management. The miniaturized device was successfully implanted in all 30 patients, without acute Major Adverse Cardiac and Neurological Events (MACNE). At 3 months, freedom from short-term MACNE was 97%. Agreement between sensor-calculated LAP and PCWP was consistent, with a mean difference of -0.22±4.92mmHg, the correlation coefficient and the Lin's Concordance Correlation Coefficient values were equal to 0.79 (P<0.0001) and 0.776 (95%CI=0.582-0.886), respectively. Preliminary experience with VLAP-based HF management was associated with significant improvements in NYHA functional class (32% of patients reached NYHA II class at 6 months, P<0.005; 60% of patients at 12 months, P<0.005) and 6-minute walk-test distance (from 244.59±119.59m at baseline to 311.78±129.88m after 6 months, P<0.05, and 343.95±146.15m after 12 months, P<0.05). Conclusion: The V-LAPTM monitoring system proved to be generally safe and provided a good correlation with invasive PCWP. Initial evidence also suggests possible improvement in HF clinical symptoms. This artic

Published
2023

2. Atrial Giant Cell Myocarditis as a Cause of Heart Failure

Author

Paitazoglou, Christina, Bergmann, Martin W., Tiemann, Katharina, Wiese, Andrea, Schäfer, Ulrich, Schwarz, Arne, Eitel, Ingo, and Montenbruck, Moritz

Subjects
atrial giant cell myocarditis, AF, atrial fibrillation, RA, right atrium, heart failure, Case Report, TEE, transesophageal echocardiography, HF, heart failure, Ig, immunoglobulin, LA, left atrium, cardiac magnetic resonance, Clinical Case, CMR, cardiac magnetic resonance, ANCA, antineutrophil cytoplasmic antibody, cardiovascular system, magnetic resonance imaging, GCM, giant cell myocarditis, Cardiology and Cardiovascular Medicine
Abstract

We present a patient with acute heart failure and new onset atrial fibrillation secondary to giant cell myocarditis with lone atrial involvement. The diagnosis was managed with cardiac magnetic resonance and confirmed by interventionally guided biopsy. In the future, diagnosis could be managed noninvasively for this rare entity as the gold standard. (Level of Difficulty: Advanced.), Graphical abstract

Published
2022

4. Osteosynthese nach sekundär dislozierter Gehweiler I-Fraktur mit hinterer Bogenschluss-Störung - Case Report

Author

Wiese, Andrea, Arand, Markus, and Seitz, Daniel H.

Subjects
HWK-Fraktur Halo-Fixateur Osteosynthese, ddc: 610, 610 Medical sciences, Medicine
Abstract

Fragestellung: Wir berichten von einem 22-jährigen Mann, welcher infolge eines Sturzes eine HWK-1-Fraktur vom Typ Gehweiler I erlitt. Bei dem Patienten liegt in eine kongenitale hintere Bogenschluss-Störung vor. Zunächst erfolgte die Versorgung mittels Halo-Fixateur. Bei sekundärer[zum vollständigen Text gelangen Sie über die oben angegebene URL], Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU 2016)

Published
2016

5. Funktionelle Aspekte der postoperativen Schmerztherapie bei Patienten nach elektiver Implantation von Knie-Totalendoprothesen

Author

Wiese, Andrea Anneliese and Pape, Hans-Christoph

Subjects
Periphere Infiltrationsanästhesie, knee joint, Kniegelenk, patient-controlled analgesia, peripheral anaesthesia, Patientengesteuerte Analgesie, pain therapy, Medizin, Epiduralanästhesie, ddc:610, Schmerztherapie, epidural anaesthesia
Abstract

In a clinical trial, three established methods for postoperative pain therapy in patients undergoing knee-replacement surgery, were compared according to their functional outcome. Patient-controlled piritramide-pumps (PCA) were compared with epidural analgesia (EPI) and a psoas-comparment-/sciatic catheter (PIK). In all three groups, data of active and passive motion, sensory loss, motor blockage, technical problems and complications were collected and compared. Data collection lasted for five days postop, respectively. Motor blockage was most frequent in patients from the PIK-group. Patients from the EPI-group showed more muscular strength than patients from the other groups at different points of data collection. Active and passive motion was higher in patient who received epidural analgesia during the early postoperative period. Patients from the EPI-group also showed highest passive flexion values ahead of patients from the PIK- and PCA-groups. Sensory deficits and losses were most frequent in patients from the PIK-group. Dorsal and frontal deficits declined in patients from the PIK-group, supporting previous findings that the psoas-compartment-analgesia blocks innervations of the medial knee by the obturator nerve sufficiently. The most frequent technical complication was dislocation of the pain-catheters. This happened more often in patients who had received epidural analgesia than in the other two groups. Infection, thromboembolism or overdosing of local anesthetics did not occur in this study. Taking into account all pros and cons of each method, epidural analgesia seems to be the most feasible and safe procedure for postoperative analgesia in patients undergoing knee replacement surgery. Psoas-compartment- and sciatic nerve block is not superior in terms of feasibility and motor and sensory block or loss. Sole opioid-analgesia with piritramide did not show any better results in this study.

Published
2011

11. Safety, usability, and performance of a wireless left atrial pressure monitoring system in patients with heart failure: the VECTOR-HF trial.

Author

D'Amario D, Meerkin D, Restivo A, Ince H, Sievert H, Wiese A, Schaefer U, Trani C, Bayes-Genis A, Leyva F, Whinnett ZI, Di Mario C, Jonas M, Manhal H, Amat-Santos IJ, Del Trigo M, Gal TB, Avraham BB, Hasin T, Feickert S, D'Ancona G, Altisent OA, Koren O, Caspi O, Abraham WT, Crea F, Anker SD, Kornowski R, and Perl L

Subjects
Humans, Cardiac Catheterization methods, Prospective Studies, Pulmonary Wedge Pressure, Atrial Pressure, Heart Failure
Abstract

Aims: In heart failure (HF), implantable haemodynamic monitoring devices have been shown to optimize therapy, anticipating clinical decompensation and preventing hospitalization. Direct left-sided haemodynamic sensors offer theoretical benefits beyond pulmonary artery pressure monitoring systems. We evaluated the safety, usability, and performance of a novel left atrial pressure (LAP) monitoring system in HF patients., Methods and Results: The VECTOR-HF study (NCT03775161) was a first-in-human, prospective, multicentre, single-arm, clinical trial enrolling 30 patients with HF. The device consisted of an interatrial positioned leadless sensor, able to transmit LAP data wirelessly. After 3 months, a right heart catheterization was performed to correlate mean pulmonary capillary wedge pressure (PCWP) with simultaneous mean LAP obtained from the device. Remote LAP measurements were then used to guide patient management. The miniaturized device was successfully implanted in all 30 patients, without acute major adverse cardiac and neurological events (MACNE). At 3 months, freedom from short-term MACNE was 97%. Agreement between sensor-calculated LAP and PCWP was consistent, with a mean difference of -0.22 ± 4.92 mmHg, the correlation coefficient and the Lin's concordance correlation coefficient values were equal to 0.79 (p < 0.0001) and 0.776 (95% confidence interval 0.582-0.886), respectively. Preliminary experience with V-LAP-based HF management was associated with significant improvements in New York Heart Association (NYHA) functional class (32% of patients reached NYHA class II at 6 months, p < 0.005; 60% of patients at 12 months, p < 0.005) and 6-min walk test distance (from 244.59 ± 119.59 m at baseline to 311.78 ± 129.88 m after 6 months, p < 0.05, and 343.95 ± 146.15 m after 12 months, p < 0.05)., Conclusion: The V-LAP™ monitoring system proved to be generally safe and provided a good correlation with invasive PCWP. Initial evidence also suggests possible improvement in HF clinical symptoms., (© 2023 The Authors. European Journal of Heart Failure published by John Wiley & Sons Ltd on behalf of European Society of Cardiology.)

Published
2023
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