626 results on '"Wiertz, Emmanuel"'
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2. Proinsulin degradation and presentation of a proinsulin B-chain autoantigen involves ER-associated protein degradation (ERAD)-enzyme UBE2G2
3. Quality Control of ER Membrane Proteins by the RNF185/Membralin Ubiquitin Ligase Complex
4. Elucidating virus-host interactions and viral immune evasion strategies using genetic editing and screening technologies
5. CRISPR/Cas9-mediated genome editing of the thymidine kinase gene in a clinical HSV-1 isolate identifies F289S as novel acyclovir-resistant mutation
6. Proinsulin degradation and presentation of a proinsulin B-chain autoantigen involves ER-associated protein degradation (ERAD)-enzyme UBE2G2
7. CRISPR/Cas9-mediated genome editing of the thymidine kinase gene in a clinical HSV-1 isolate identifies F289S as novel acyclovir-resistant mutation
8. New insights into the structure of the MHC class I peptide-loading complex and mechanisms of TAP inhibition by viral immune evasion proteins
9. Recruitment of the p97 ATPase and Ubiquitin Ligases to the Site of Retrotranslocation at the Endoplasmic Reticulum Membrane
10. Recent advances in viral evasion of the MHC Class I processing pathway
11. Immune Evasion by Epstein-Barr Virus
12. A Flow Cytometry-Based Approach to Unravel Viral Interference with the MHC Class I Antigen Processing and Presentation Pathway
13. Viral immune evasion: Lessons in MHC class I antigen presentation
14. Viral interference with antigen presentation: Trapping TAP
15. MHC class I molecules are preferentially ubiquitinated on endoplasmic reticulum luminal residues during HRD1 ubiquitin E3 ligase-mediated dislocation
16. Endogenous HLA class II epitopes that are immunogenic in vivo show distinct behavior toward HLA-DM and its natural inhibitor HLA-DO
17. The SARS-CoV-2 accessory factor ORF7a downregulates MHC class I surface expression
18. Ube2j2 Ubiquitinates Hydroxylated Amino Acids on ER-Associated Degradation Substrates
19. The TRC8 E3 Ligase Ubiquitinates MHC Class I Molecules before Dislocation from the ER
20. Enhanced antigen cross-presentation in human colorectal cancer-associated fibroblasts through upregulation of the lysosomal protease cathepsin S
21. Structural and functional analysis of the TAP-inhibiting UL49.5 proteins of varicelloviruses
22. Inhibition of mouse TAP by immune evasion molecules encoded by non-murine herpesviruses
23. Viral evasion of T cell immunity: ancient mechanisms offering new applications
24. Ubiquitination of Serine, Threonine, or Lysine Residues on the Cytoplasmic Tail Can Induce ERAD of MHC-l by Viral E3 Ligase mK3
25. Host Shutoff during Productive Epstein-Barr Virus Infection Is Mediated by BGLF5 and May Contribute to Immune Evasion
26. Enhanced antigen cross-presentation in human colorectal cancer-associated fibroblasts through upregulation of the lysosomal protease cathepsin S
27. A genome-wide high-complexity shRNA library screen identifies novel factors in MHC class I trafficking and degradation
28. Cowpox Virus Inhibits the Transporter Associated with Antigen Processing to Evade T Cell Recognition
29. Two Mechanistically Distinct Immune Evasion Proteins of Cowpox Virus Combine to Avoid Antiviral CD8 T Cells
30. A Bridge Crosses the Active-Site Canyon of the Epstein–Barr Virus Nuclease with DNase and RNase Activities
31. CYP3A4 ubiquitination by gp78 (the tumor autocrine motility factor receptor, AMFR) and CHIP E3 ligases
32. Immune Evasion by Epstein-Barr Virus
33. Signaling of a Varicelloviral Factor across the Endoplasmic Reticulum Membrane Induces Destruction of the Peptide-loading Complex and Immune Evasion
34. Epstein-Barr virus evasion of CD8 + and CD4 + T cell immunity via concerted actions of multiple gene products
35. Alternative Ii-independent antigen-processing pathway in leukemic blasts involves TAP-dependent peptide loading of HLA class II complexes
36. Construction of an African Swine Fever Virus phagemid library through non-homologues random recombination
37. A class II MHC-targeted vaccine elicits immunity against SARS-CoV-2 and its variants
38. Signaling of a varicelloviral factor across the endoplasmic reticulum membrane induces destruction of the peptide-loading complex and immune evasion
39. The nested open reading frame in the Epstein-Barr virus nuclear antigen-1 mRNA encodes a protein capable of inhibiting antigen presentation in cis
40. In cis inhibition of antigen processing by the latency-associated nuclear antigen I of Kaposi sarcoma Herpes virus
41. Varicelloviruses avoid T cell recognition by UL49.5-mediated inactivation of the transporter associated with antigen processing
42. Evaluation of Viral Interference with MHC Class I-Restricted Antigen Processing and Presentation Using a Flow Cytometry-Based Approach
43. Viral immune evasion: a masterpiece of evolution
44. Ubiquitination of MHC Class I Heavy Chains Is Essential for Dislocation by Human Cytomegalovirus-encoded US2 but Not US11
45. Interference with T cell receptor-HLA-DR interactions by Epstein-Bart virus gp42 results in reduced T helper cell recognition
46. Human cytomegalovirus-encoded US2 and US11 target unassembled MHC class I heavy chains for degradation
47. Exploiting human herpesvirus immune evasion for therapeutic gain: potential and pitfalls
48. A Broad-Spectrum Antiviral Peptide Blocks Infection of Viruses by Binding to Phosphatidylserine in the Viral Envelope
49. Distinct kinetics and dynamics of cross-presentation in liver sinusoidal endothelial cells compared to dendritic cells#
50. Reduced human leukocyte antigen expression in advanced-stage Ewing sarcoma: implications for immune recognition
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