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1. Whole pelvis vs. hemi pelvis elective nodal radiotherapy in patients with PSMA-positive nodal recurrence after radical prostatectomy - a retrospective multi-institutional propensity score analysis

Author

Trapp, Christian, Aebersold, Daniel M., Belka, Claus, Casuscelli, Jozefina, Emmett, Louise, Eze, Chukwuka, Fanti, Stefano, Farolfi, Andrea, Fendler, Wolfgang, Grosu, Anca-Ligia, Guckenberger, Matthias, Hruby, George, Kirste, Simon, Koerber, Stefan A., Kroeze, Stephanie, Peeken, Jan C., Rogowski, Paul, Scharl, Sophia, Shelan, Mohamed, Spohn, Simon K. B., Strouthos, Iosif, Unterrainer, Lena, Vogel, Marco, Wiegel, Thomas, Zamboglou, Constantinos, and Schmidt-Hegemann, Nina-Sophie

Published
2024
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2. The prognostic significance of a negative PSMA-PET scan prior to salvage radiotherapy following radical prostatectomy

Author

Adebahr, Sonja, Althaus, Alexander, Scharl, Sophia, Strouthos, Iosif, Farolfi, Andrea, Serani, Francesca, Lanzafame, Helena, Trapp, Christian, Koerber, Stefan A., Peeken, Jan C., Vogel, Marco M. E., Vrachimis, Alexis, Spohn, Simon K. B., Grosu, Anca-Ligia, Kroeze, Stephanie G. C., Guckenberger, Matthias, Fanti, Stefano, Hruby, George, Emmett, Louise, Belka, Claus, Schmidt-Hegemann, Nina-Sophie, Henkenberens, Christoph, Aebersold, Daniel M., Wiegel, Thomas, Afshar-Oromieh, Ali, Zamboglou, Constantinos, and Shelan, Mohamed

Published
2024
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3. Harninkontinenz nach radikaler Prostatektomie beim Prostatakarzinom – aktuelle Daten von 17.149 Patienten aus 125 zertifizierten Zentren

Author

Kowalski, Christoph, Sibert, Nora Tabea, Hammerer, Peter, Wesselmann, Simone, Feick, Günter, Carl, Ernst-Günther, Klotz, Theodor, Apel, Hendrik, Dieng, Sebastian, Nyarangi-Dix, Joanne, Knoll, Thomas, Reike, Moritz Johannes, Duwe, Gregor, Bartolf, Elisabeth, Steiner, Thomas, Borowitz, Rainer, Lümmen, Gerd, Seitz, Anna Katharina, Pfitzenmaier, Jesco, Aziz, Atiqullah, Brock, Marko, Berger, Frank Peter, Kaftan, Björn Theodor, Grube, Christian, Häfner, Tim, Hamza, Amir, Schmelz, Hans, Haas, Jürgen, Lenart, Sebastian, Lafita, Anselm, Sippel, Carsten, Winter, Alexander, Kedia, George, Hadaschik, Boris, Varga, Zoltan, Buse, Stephan, Richter, Matthias, Distler, Florian, Simon, Jörg, Wiegel, Thomas, Baltes, Stefan, Janitzky, Andreas, Sommer, Jens Peter, Hijazi, Sameh, Fülkell, Philipp, Harke, Nina N., Bolenz, Christian, Khalil, Christian, Breidenbach, Clara, Tennstedt, Pierre, and Burchardt, Martin

Published
2024
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4. EAU-EANM-ESTRO-ESUR-ISUP-SIOG Guidelines on Prostate Cancer. Part II—2024 Update: Treatment of Relapsing and Metastatic Prostate Cancer

Author

Tilki, Derya, van den Bergh, Roderick C.N., Briers, Erik, Van den Broeck, Thomas, Brunckhorst, Oliver, Darraugh, Julie, Eberli, Daniel, De Meerleer, Gert, De Santis, Maria, Farolfi, Andrea, Gandaglia, Giorgio, Gillessen, Silke, Grivas, Nikolaos, Henry, Ann M., Lardas, Michael, J.L.H. van Leenders, Geert, Liew, Matthew, Linares Espinos, Estefania, Oldenburg, Jan, van Oort, Inge M., Oprea-Lager, Daniela E., Ploussard, Guillaume, Roberts, Matthew J., Rouvière, Olivier, Schoots, Ivo G., Schouten, Natasha, Smith, Emma J., Stranne, Johan, Wiegel, Thomas, Willemse, Peter-Paul M., and Cornford, Philip

Published
2024
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5. EAU-EANM-ESTRO-ESUR-ISUP-SIOG Guidelines on Prostate Cancer—2024 Update. Part I: Screening, Diagnosis, and Local Treatment with Curative Intent

Author

Cornford, Philip, van den Bergh, Roderick C.N., Briers, Erik, Van den Broeck, Thomas, Brunckhorst, Oliver, Darraugh, Julie, Eberli, Daniel, De Meerleer, Gert, De Santis, Maria, Farolfi, Andrea, Gandaglia, Giorgio, Gillessen, Silke, Grivas, Nikolaos, Henry, Ann M., Lardas, Michael, van Leenders, Geert J.L.H., Liew, Matthew, Linares Espinos, Estefania, Oldenburg, Jan, van Oort, Inge M., Oprea-Lager, Daniela E., Ploussard, Guillaume, Roberts, Matthew J., Rouvière, Olivier, Schoots, Ivo G., Schouten, Natasha, Smith, Emma J., Stranne, Johan, Wiegel, Thomas, Willemse, Peter-Paul M., and Tilki, Derya

Published
2024
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6. A Systematic Review of the Efficacy and Toxicity of Brachytherapy Boost Combined with External Beam Radiotherapy for Nonmetastatic Prostate Cancer

Author

Slevin, Finbar, Zattoni, Fabio, Checcucci, Enrico, Cumberbatch, Marcus G.K., Nacchia, Antonio, Cornford, Philip, Briers, Erik, De Meerleer, Gert, De Santis, Maria, Eberli, Daniel, Gandaglia, Giorgio, Gillessen, Silke, Grivas, Nikolaos, Liew, Matthew, Linares Espinós, Estefania E., Oldenburg, Jan, Oprea-Lager, Daniela E., Ploussard, Guillaume, Rouvière, Olivier, Schoots, Ivo G., Smith, Emma Jane, Stranne, Johan, Tilki, Derya, Smith, Catrin Tudur, Van Den Bergh, Roderick C.N., Van Oort, Inge M., Wiegel, Thomas, Yuan, Cathy Y., Van den Broeck, Thomas, and Henry, Ann M.

Published
2024
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8. European association of urology risk stratification predicts outcome in patients receiving PSMA-PET-planned salvage radiotherapy for biochemical recurrence following radical prostatectomy

Author

Scharl, Sophia, Zamboglou, Constantinos, Strouthos, Iosif, Farolfi, Andrea, Serani, Francesca, Koerber, Stefan A., Debus, Jürgen, Peeken, Jan C., Vogel, Marco M.E., Kroeze, Stephanie G.C., Guckenberger, Matthias, Krafcsik, Manuel, Hruby, George, Emmett, Louise, Schmidt-Hegemann, Nina-Sophie, Trapp, Christian, Spohn, Simon K.B., Henkenberens, Christoph, Mayer, Benjamin, Shelan, Mohamed, Aebersold, Daniel M., Thamm, Reinhard, and Wiegel, Thomas

Published
2024
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9. European Association of Urology Biochemical Recurrence Risk Classification as a Decision Tool for Salvage Radiotherapy—A Multicenter Study

Author

Preisser, Felix, Abrams-Pompe, Raisa S., Stelwagen, Piter Jan, Böhmer, Dirk, Zattoni, Fabio, Magli, Alessandro, Rivas, Juan Gómez, Dilme, Roser Vives, Sepulcri, Matteo, Eguibar, Aritz, Heidegger, Isabel, Arnold, Christoph, Fankhauser, Christian D., Chun, Felix K.-H., van der Poel, Henk, Gandaglia, Giorgio, Wiegel, Thomas, van den Bergh, Roderick C.N., and Tilki, Derya

Published
2024
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10. Multi-institutional Development and External Validation of a Machine Learning Model for the Prediction of Distant Metastasis in Patients Treated by Salvage Radiotherapy for Biochemical Failure After Radical Prostatectomy

Author

Sabbagh, Ali, Tilki, Derya, Feng, Jean, Huland, Hartwig, Graefen, Markus, Wiegel, Thomas, Böhmer, Dirk, Hong, Julian C., Valdes, Gilmer, Cowan, Janet E., Cooperberg, Matthew, Feng, Felix Y., Mohammad, Tarek, Shelan, Mohamed, D'Amico, Anthony V., Carroll, Peter R., and Mohamad, Osama

Published
2024
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11. PSMA-PET/CT-guided salvage radiotherapy in recurrent or persistent prostate cancer and PSA < 0.2 ng/ml

Author

Solomonidou, Nantia, Germanou, Daphnie, Strouthos, Iosif, Karagiannis, Efstratios, Farolfi, Andrea, Koerber, Stefan A., Debus, Juergen, Peeken, Jan C., Vogel, Marco E., Vrachimis, Alexis, Spohn, Simon K. B., Shelan, Mohamed, Aebersold, Daniel, Grosu, Anca-Ligia, Ceci, Francesco, Kroeze, Stephanie G. C., Guckenberger, Matthias, Fanti, Stefano, Belka, Claus, Hruby, George, Scharl, S., Wiegel, Thomas, Bartenstein, Peter, Henkenberens, Christoph, Emmett, Louise, Schmidt-Hegemann, Nina Sophie, Ferentinos, Konstantinos, and Zamboglou, Constantinos

Published
2023
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13. Development and External Validation of a Machine Learning Model for Prediction of Lymph Node Metastasis in Patients with Prostate Cancer

Author

Sabbagh, Ali, Washington, Samuel L., 3rd, Tilki, Derya, Hong, Julian C., Feng, Jean, Valdes, Gilmer, Chen, Ming-Hui, Wu, Jing, Huland, Hartwig, Graefen, Markus, Wiegel, Thomas, Böhmer, Dirk, Cowan, Janet E., Cooperberg, Matthew, Feng, Felix Y., Roach, Mack, 3rd, Trock, Bruce J., Partin, Alan W., D'Amico, Anthony V., Carroll, Peter R., and Mohamad, Osama

Published
2023
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15. Genomic Classifiers in Personalized Prostate Cancer Radiation Therapy Approaches: A Systematic Review and Future Perspectives Based on International Consensus

Author

Spohn, Simon K.B., Draulans, Cédric, Kishan, Amar U., Spratt, Daniel, Ross, Ashley, Maurer, Tobias, Tilki, Derya, Berlin, Alejandro, Blanchard, Pierre, Collins, Sean, Bronsert, Peter, Chen, Ronald, Pra, Alan Dal, de Meerleer, Gert, Eade, Thomas, Haustermans, Karin, Hölscher, Tobias, Höcht, Stefan, Ghadjar, Pirus, Davicioni, Elai, Heck, Matthias, Kerkmeijer, Linda G.W., Kirste, Simon, Tselis, Nikolaos, Tran, Phuoc T., Pinkawa, Michael, Pommier, Pascal, Deltas, Constantinos, Schmidt-Hegemann, Nina-Sophie, Wiegel, Thomas, Zilli, Thomas, Tree, Alison C., Qiu, Xuefeng, Murthy, Vedang, Epstein, Jonathan I., Graztke, Christian, Gao, Xin, Grosu, Anca L., Kamran, Sophia C., and Zamboglou, Constantinos

Published
2023
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16. Impact of Epithelial Histological Types, Subtypes, and Growth Patterns on Oncological Outcomes for Patients with Nonmetastatic Prostate Cancer Treated with Curative Intent: A Systematic Review

Author

Marra, Giancarlo, van Leenders, Geert J.L.H., Zattoni, Fabio, Kesch, Claudia, Rajwa, Pawel, Cornford, Philip, van der Kwast, Theodorus, van den Bergh, Roderick C.N., Briers, Erik, Van den Broeck, Thomas, De Meerleer, Gert, De Santis, Maria, Eberli, Daniel, Farolfi, Andrea, Gillessen, Silke, Grivas, Nikolaos, Grummet, Jeremy P., Henry, Ann M., Lardas, Michael, Lieuw, Matt, Linares Espinós, Estefania, Mason, Malcolm D., O'Hanlon, Shane, van Oort, Inge M., Oprea-Lager, Daniela E., Ploussard, Guillaume, Rouvière, Olivier, Schoots, Ivo.G., Stranne, Johan, Tilki, Derya, Wiegel, Thomas, Willemse, Peter-Paul M., Mottet, Nicolas, and Gandaglia, Giorgio

Published
2023
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17. Salvage radiotherapy is effective in patients with PSMA-PET-negative biochemical recurrence- results of a retrospective study

Author

Scharl, Sophia, Zamboglou, Constantinos, Strouthos, Iosif, Farolfi, Andrea, Serani, Francesca, Lanzafame, Helena, Giuseppe Morganti, Alessio, Trapp, Christian, Koerber, Stefan A., Debus, Jürgen, Peeken, Jan C., Vogel, Marco M.E., Vrachimis, Alexis, Spohn, Simon K.B., Ruf, Juri, Grosu, Anca-Ligia, Ceci, Francesco, Fendler, Wolfgang P., Bartenstein, Peter, Kroeze, Stephanie G.C., Guckenberger, Matthias, Krafcsik, Manuel, Klopscheck, Christina, Fanti, Stefano, Hruby, George, Emmett, Louise, Belka, Claus, Stief, Christian, Schmidt-Hegemann, Nina-Sophie, Henkenberens, Christoph, Mayer, Benjamin, Miksch, Jonathan, Shelan, Mohamed, Aebersold, Daniel M., Thamm, Reinhard, and Wiegel, Thomas

Published
2023
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23. Metastasis-Free Survival and Patterns of Distant Metastatic Disease After Prostate-Specific Membrane Antigen Positron Emission Tomography (PSMA-PET)-Guided Salvage Radiation Therapy in Recurrent or Persistent Prostate Cancer After Prostatectomy

Author

Zamboglou, Constantinos, Strouthos, Iosif, Sahlmann, Joerg, Farolfi, Andrea, Serani, Francesca, Medici, Federica, Cavallini, Letizia, Morganti, Alessio Guiseppe, Trapp, Christian, Koerber, Stefan A., Peeken, Jan C., Vogel, Marco M.E., Schiller, Kilian, Combs, Stephanie E., Eiber, Matthias, Vrachimis, Alexis, Ferentinos, Konstantinos, Spohn, Simon K.B., Kirste, Simon, Gratzke, Christian, Ruf, Juri, Grosu, Anca-Ligia, Ceci, Francesco, Fendler, Wolfgang P., Miksch, Jonathan, Kroeze, Stephanie, Guckenberger, Matthias, Lanzafame, Helena, Fanti, Stefano, Hruby, George, Wiegel, Thomas, Emmett, Louise, Schmidt-Hegemann, Nina Sophie, and Henkenberens, Christoph

Published
2022
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24. Evaluation of Oncological Outcomes and Data Quality in Studies Assessing Nerve-sparing Versus Non–Nerve-sparing Radical Prostatectomy in Nonmetastatic Prostate Cancer: A Systematic Review

Author

Moris, Lisa, Gandaglia, Giorgio, Vilaseca, Antoni, Van den Broeck, Thomas, Briers, Erik, De Santis, Maria, Gillessen, Silke, Grivas, Nikos, O’Hanlon, Shane, Henry, Ann, Lam, Thomas B., Lardas, Michael, Mason, Malcolm, Oprea-Lager, Daniela, Ploussard, Guillaume, Rouviere, Olivier, Schoots, Ivo G., van der Poel, Henk, Wiegel, Thomas, Willemse, Peter-Paul, Yuan, Cathy Y., Grummet, Jeremy P., Tilki, Derya, van den Bergh, Roderick C.N., Cornford, Philip, and Mottet, Nicolas

Published
2022
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25. Patient- and Tumour-related Prognostic Factors for Urinary Incontinence After Radical Prostatectomy for Nonmetastatic Prostate Cancer: A Systematic Review and Meta-analysis

Author

Lardas, Michael, Grivas, Nikos, Debray, Thomas P.A., Zattoni, Fabio, Berridge, Christopher, Cumberbatch, Marcus, Van den Broeck, Thomas, Briers, Erik, De Santis, Maria, Farolfi, Andrea, Fossati, Nicola, Gandaglia, Giorgio, Gillessen, Silke, O’Hanlon, Shane, Henry, Ann, Liew, Matthew, Mason, Malcolm, Moris, Lisa, Oprea-Lager, Daniela, Ploussard, Guillaume, Rouviere, Olivier, Schoots, Ivo G., van der Kwast, Theodorus, van der Poel, Henk, Wiegel, Thomas, Willemse, Peter-Paul, Yuan, Cathy Y., Grummet, Jeremy P., Tilki, Derya, van den Bergh, Roderick C.N., Lam, Thomas B., Cornford, Philip, and Mottet, Nicolas

Published
2022
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26. Systematic Review of Active Surveillance for Clinically Localised Prostate Cancer to Develop Recommendations Regarding Inclusion of Intermediate-risk Disease, Biopsy Characteristics at Inclusion and Monitoring, and Surveillance Repeat Biopsy Strategy

Author

Willemse, Peter-Paul M., Davis, Niall F., Grivas, Nikolaos, Zattoni, Fabio, Lardas, Michael, Briers, Erik, Cumberbatch, Marcus G., De Santis, Maria, Dell'Oglio, Paolo, Donaldson, James F., Fossati, Nicola, Gandaglia, Giorgio, Gillessen, Silke, Grummet, Jeremy P., Henry, Ann M., Liew, Matthew, MacLennan, Steven, Mason, Malcolm D., Moris, Lisa, Plass, Karin, O'Hanlon, Shane, Omar, Muhammad Imran, Oprea-Lager, Daniela E., Pang, Karl H., Paterson, Catherine C., Ploussard, Guillaume, Rouvière, Olivier, Schoots, Ivo G., Tilki, Derya, van den Bergh, Roderick C.N., Van den Broeck, Thomas, van der Kwast, Theodorus H., van der Poel, Henk G., Wiegel, Thomas, Yuan, Cathy Yuhong, Cornford, Philip, Mottet, Nicolas, and Lam, Thomas B.L.

Published
2022
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28. Moderately hypofractionated radiotherapy as definitive treatment for localized prostate cancer: Pattern of practice in German-speaking countries: A survey of the Prostate Cancer Expert Panel of the German Society of Radiation Oncology (DEGRO) and the Working Party on Radiation Oncology of the German Cancer Society (DKG-ARO)

Author

Shelan, Mohamed, Aebersold, Daniel M., Albrecht, Clemens, Böhmer, Dirk, Flentje, Michael, Ganswindt, Ute, Höcht, Stefan, Hölscher, Tobias, Müller, Arndt-Christian, Niehoff, Peter, Pinkawa, Michael, Schmidt-Hegemann, Nina-Sophie, Sedlmayer, Felix, Wolf, Frank, Zamboglou, Constantinos, Zips, Daniel, Wiegel, Thomas, and Ghadjar, Pirus

Published
2021
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29. Management of Patients with Advanced Prostate Cancer: The Report of the Advanced Prostate Cancer Consensus Conference APCCC 2017

Author

Gillessen, Silke, Attard, Gerhardt, Beer, Tomasz M, Beltran, Himisha, Bossi, Alberto, Bristow, Rob, Carver, Brett, Castellano, Daniel, Chung, Byung Ha, Clarke, Noel, Daugaard, Gedske, Davis, Ian D, de Bono, Johann, dos Reis, Rodolfo Borges, Drake, Charles G, Eeles, Ros, Efstathiou, Eleni, Evans, Christopher P, Fanti, Stefano, Feng, Felix, Fizazi, Karim, Frydenberg, Mark, Gleave, Martin, Halabi, Susan, Heidenreich, Axel, Higano, Celestia S, James, Nicolas, Kantoff, Philip, Kellokumpu-Lehtinen, Pirkko-Liisa, Khauli, Raja B, Kramer, Gero, Logothetis, Chris, Maluf, Fernando, Morgans, Alicia K, Morris, Michael J, Mottet, Nicolas, Murthy, Vedang, Oh, William, Ost, Piet, Padhani, Anwar R, Parker, Chris, Pritchard, Colin C, Roach, Mack, Rubin, Mark A, Ryan, Charles, Saad, Fred, Sartor, Oliver, Scher, Howard, Sella, Avishay, Shore, Neal, Smith, Matthew, Soule, Howard, Sternberg, Cora N, Suzuki, Hiroyoshi, Sweeney, Christopher, Sydes, Matthew R, Tannock, Ian, Tombal, Bertrand, Valdagni, Riccardo, Wiegel, Thomas, and Omlin, Aurelius

Subjects
Cancer, Urologic Diseases, Aging, Prostate Cancer, Good Health and Well Being, Humans, Male, Neoplasm Staging, Practice Guidelines as Topic, Prostatic Neoplasms, Advanced and high-risk localized prostate cancer, Castration-naive and castration-resistant prostate cancer, Therapeutics, Consensus, Oligometastatic prostate cancer, Clinical Sciences, Urology & Nephrology
Abstract

BackgroundIn advanced prostate cancer (APC), successful drug development as well as advances in imaging and molecular characterisation have resulted in multiple areas where there is lack of evidence or low level of evidence. The Advanced Prostate Cancer Consensus Conference (APCCC) 2017 addressed some of these topics.ObjectiveTo present the report of APCCC 2017.Design, setting, and participantsTen important areas of controversy in APC management were identified: high-risk localised and locally advanced prostate cancer; "oligometastatic" prostate cancer; castration-naïve and castration-resistant prostate cancer; the role of imaging in APC; osteoclast-targeted therapy; molecular characterisation of blood and tissue; genetic counselling/testing; side effects of systemic treatment(s); global access to prostate cancer drugs. A panel of 60 international prostate cancer experts developed the program and the consensus questions.Outcome measurements and statistical analysisThe panel voted publicly but anonymously on 150 predefined questions, which have been developed following a modified Delphi process.Results and limitationsVoting is based on panellist opinion, and thus is not based on a standard literature review or meta-analysis. The outcomes of the voting had varying degrees of support, as reflected in the wording of this article, as well as in the detailed voting results recorded in Supplementary data.ConclusionsThe presented expert voting results can be used for support in areas of management of men with APC where there is no high-level evidence, but individualised treatment decisions should as always be based on all of the data available, including disease extent and location, prior therapies regardless of type, host factors including comorbidities, as well as patient preferences, current and emerging evidence, and logistical and economic constraints. Inclusion of men with APC in clinical trials should be strongly encouraged. Importantly, APCCC 2017 again identified important areas in need of trials specifically designed to address them.Patient summaryThe second Advanced Prostate Cancer Consensus Conference APCCC 2017 did provide a forum for discussion and debates on current treatment options for men with advanced prostate cancer. The aim of the conference is to bring the expertise of world experts to care givers around the world who see less patients with prostate cancer. The conference concluded with a discussion and voting of the expert panel on predefined consensus questions, targeting areas of primary clinical relevance. The results of these expert opinion votes are embedded in the clinical context of current treatment of men with advanced prostate cancer and provide a practical guide to clinicians to assist in the discussions with men with prostate cancer as part of a shared and multidisciplinary decision-making process.

Published
2018

30. Correction to: Value of PET imaging for radiation therapy

Author

Lapa, Constantin, Nestle, Ursula, Albert, Nathalie L., Baues, Christian, Beer, Ambros, Buck, Andreas, Budach, Volker, Bütof, Rebecca, Combs, Stephanie E., Derlin, Thorsten, Eiber, Matthias, Fendler, Wolfgang P., Furth, Christian, Gani, Cihan, Gkika, Eleni, Grosu, Anca-L., Henkenberens, Christoph, Ilhan, Harun, Löck, Steffen, Marnitz-Schulze, Simone, Miederer, Matthias, Mix, Michael, Nicolay, Nils H., Niyazi, Maximilian, Pöttgen, Christoph, Rödel, Claus M., Schatka, Imke, Schwarzenboeck, Sarah M., Todica, Andrei S., Weber, Wolfgang, Wegen, Simone, Wiegel, Thomas, Zamboglou, Constantinos, Zips, Daniel, Zöphel, Klaus, Zschaeck, Sebastian, Thorwarth, Daniela, and Troost, Esther G. C.

Published
2022
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31. Radiotherapy in nodal oligorecurrent prostate cancer

Author

Pinkawa, Michael, Aebersold, Daniel M., Böhmer, Dirk, Flentje, Michael, Ghadjar, Pirus, Schmidt-Hegemann, Nina-Sophie, Höcht, Stefan, Hölscher, Tobias, Müller, Arndt-Christian, Niehoff, Peter, Sedlmayer, Felix, Wolf, Frank, Zamboglou, Constantinos, Zips, Daniel, and Wiegel, Thomas

Published
2021
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32. A Systematic Review of Focal Ablative Therapy for Clinically Localised Prostate Cancer in Comparison with Standard Management Options: Limitations of the Available Evidence and Recommendations for Clinical Practice and Further Research

Author

Bates, Anthony S., Ayers, Jennifer, Kostakopoulos, Nikolaos, Lumsden, Thomas, Schoots, Ivo G., Willemse, Peter-Paul M., Yuan, Yuhong, van den Bergh, Roderick C.N., Grummet, Jeremy P., van der Poel, Henk G., Rouvière, Olivier, Moris, Lisa, Cumberbatch, Marcus G., Lardas, Michael, Liew, Matthew, Van den Broeck, Thomas, Gandaglia, Giorgio, Fossati, Nicola, Briers, Erik, De Santis, Maria, Fanti, Stefano, Gillessen, Silke, Oprea-Lager, Daniela E., Ploussard, Guillaume, Henry, Ann M., Tilki, Derya, van der Kwast, Theodorus H., Wiegel, Thomas, N’Dow, James, Mason, Malcolm D., Cornford, Philip, Mottet, Nicolas, and Lam, Thomas B.L.

Published
2021
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37. Biochemical Recurrence in Prostate Cancer: The European Association of Urology Prostate Cancer Guidelines Panel Recommendations

Author

Van den Broeck, Thomas, van den Bergh, Roderick C.N., Briers, Erik, Cornford, Philip, Cumberbatch, Marcus, Tilki, Derya, De Santis, Maria, Fanti, Stefano, Fossati, Nicola, Gillessen, Silke, Grummet, Jeremy P., Henry, Ann M., Lardas, Michael, Liew, Matthew, Mason, Malcolm, Moris, Lisa, Schoots, Ivo G., van der Kwast, Theodorus, van der Poel, Henk, Wiegel, Thomas, Willemse, Peter-Paul M., Rouvière, Olivier, Lam, Thomas B., and Mottet, Nicolas

Published
2020
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38. A Systematic Review of the Efficacy and Toxicity of Brachytherapy Boost Combined with External Beam Radiotherapy for Nonmetastatic Prostate Cancer

Author

Slevin, Finbar, primary, Zattoni, Fabio, additional, Checcucci, Enrico, additional, Cumberbatch, Marcus G.K., additional, Nacchia, Antonio, additional, Cornford, Philip, additional, Briers, Erik, additional, De Meerleer, Gert, additional, De Santis, Maria, additional, Eberli, Daniel, additional, Gandaglia, Giorgio, additional, Gillessen, Silke, additional, Grivas, Nikolaos, additional, Liew, Matthew, additional, Linares Espinós, Estefania E., additional, Oldenburg, Jan, additional, Oprea-Lager, Daniela E., additional, Ploussard, Guillaume, additional, Rouvière, Olivier, additional, Schoots, Ivo G., additional, Smith, Emma Jane, additional, Stranne, Johan, additional, Tilki, Derya, additional, Smith, Catrin Tudur, additional, Van Den Bergh, Roderick C.N., additional, Van Oort, Inge M., additional, Wiegel, Thomas, additional, Yuan, Cathy Y., additional, Van den Broeck, Thomas, additional, and Henry, Ann M., additional

Published
2023
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42. Harninkontinenz nach radikaler Prostatektomie beim Prostatakarzinom – aktuelle Daten von 17.149 Patienten aus 125 zertifizierten Zentren

Author

Kowalski, Christoph, primary, Sibert, Nora Tabea, additional, Hammerer, Peter, additional, Wesselmann, Simone, additional, Feick, Günter, additional, Carl, Ernst-Günther, additional, Klotz, Theodor, additional, Apel, Hendrik, additional, Dieng, Sebastian, additional, Nyarangi-Dix, Joanne, additional, Knoll, Thomas, additional, Reike, Moritz Johannes, additional, Duwe, Gregor, additional, Bartolf, Elisabeth, additional, Steiner, Thomas, additional, Borowitz, Rainer, additional, Lümmen, Gerd, additional, Seitz, Anna Katharina, additional, Pfitzenmaier, Jesco, additional, Aziz, Atiqullah, additional, Brock, Marko, additional, Berger, Frank Peter, additional, Kaftan, Björn Theodor, additional, Grube, Christian, additional, Häfner, Tim, additional, Hamza, Amir, additional, Schmelz, Hans, additional, Haas, Jürgen, additional, Lenart, Sebastian, additional, Lafita, Anselm, additional, Sippel, Carsten, additional, Winter, Alexander, additional, Kedia, George, additional, Hadaschik, Boris, additional, Varga, Zoltan, additional, Buse, Stephan, additional, Richter, Matthias, additional, Distler, Florian, additional, Simon, Jörg, additional, Wiegel, Thomas, additional, Baltes, Stefan, additional, Janitzky, Andreas, additional, Sommer, Jens Peter, additional, Hijazi, Sameh, additional, Fülkell, Philipp, additional, Harke, Nina N., additional, Bolenz, Christian, additional, Khalil, Christian, additional, Breidenbach, Clara, additional, Tennstedt, Pierre, additional, and Burchardt, Martin, additional

Published
2023
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43. 1443: Whole vs. hemi pelvis RT in patients with PSMA-positive nodal recurrence - a retrospective analysis

Author

Trapp, Christian, Aebersold, Daniel M., Belka, Claus, Casuscelli, Jozefina, Ceci, Francesco, Emmett, Louise, Fanti, Stefano, Farolfi, Andrea, Grosu, Anca-Ligia, Guckenberger, Matthias, Henkenberens, Christoph, Hruby, George, Koerber, Stefan A., Kroeze, Stephanie, Peeken, Jan C., Rogowski, Paul, Scharl, Sophia, Shelan, Mohamed, Spohn, Simon K.B., Strouthos, Iosif, Unterrainer, Lena, Vogel, Marco, Wiegel, Thomas, Zamboglou, Constantinos, and Schmidt-Hegemann, Nina-Sophie

Published
2024
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45. Impact of Epithelial Histological Types, Subtypes, and Growth Patterns on Oncological Outcomes for Patients with Nonmetastatic Prostate Cancer Treated with Curative Intent:A Systematic Review

Author

Marra, Giancarlo, van Leenders, Geert J L H, Zattoni, Fabio, Kesch, Claudia, Rajwa, Pawel, Cornford, Philip, van der Kwast, Theodorus, van den Bergh, Roderick C N, Briers, Erik, Van den Broeck, Thomas, De Meerleer, Gert, De Santis, Maria, Eberli, Daniel, Farolfi, Andrea, Gillessen, Silke, Grivas, Nikolaos, Grummet, Jeremy P, Henry, Ann M, Lardas, Michael, Lieuw, Matt, Linares Espinós, Estefania, Mason, Malcolm D, O'Hanlon, Shane, van Oort, Inge M, Oprea-Lager, Daniela E, Ploussard, Guillaume, Rouvière, Olivier, Schoots, Ivo G, Stranne, Johan, Tilki, Derya, Wiegel, Thomas, Willemse, Peter-Paul M, Mottet, Nicolas, and Gandaglia, Giorgio

Subjects
Prostate cancer, All institutes and research themes of the Radboud University Medical Center, SDG 3 - Good Health and Well-being, Urology, Urological cancers Radboud Institute for Molecular Life Sciences [Radboudumc 15], Nonmetastatic, 610 Medicine & health, Curative-intent treatment, Unconventional histology
Abstract

Item does not contain fulltext CONTEXT: The optimal management for men with prostate cancer (PCa) with unconventional histology (UH) is unknown. The outcome for these cancers might be worse than for conventional PCa and so different approaches may be needed. OBJECTIVE: To compare oncological outcomes for conventional and UH PCa in men with localized disease treated with curative intent. EVIDENCE ACQUISITION: A systematic review adhering to the Referred Reporting Items for Systematic Reviews and Meta-Analyses was prospectively registered on PROSPERO (CRD42022296013) was performed in July 2021. EVIDENCE SYNTHESIS: We screened 3651 manuscripts and identified 46 eligible studies (reporting on 1 871 814 men with conventional PCa and 6929 men with 10 different PCa UHs). Extraprostatic extension and lymph node metastases, but not positive margin rates, were more common with UH PCa than with conventional tumors. PCa cases with cribriform pattern, intraductal carcinoma, or ductal adenocarcinoma had higher rates of biochemical recurrence and metastases after radical prostatectomy than for conventional PCa cases. Lower cancer-specific survival rates were observed for mixed cribriform/intraductal and cribriform PCa. By contrast, pathological findings and oncological outcomes for mucinous and prostatic intraepithelial neoplasia (PIN)-like PCa were similar to those for conventional PCa. Limitations of this review include low-quality studies, a risk of reporting bias, and a scarcity of studies that included radiotherapy. CONCLUSIONS: Intraductal, cribriform, and ductal UHs may have worse oncological outcomes than for conventional and mucinous or PIN-like PCa. Alternative treatment approaches need to be evaluated in men with these cancers. PATIENT SUMMARY: We reviewed the literature to explore whether prostate cancers with unconventional growth patterns behave differently to conventional prostate cancers. We found that some unconventional growth patterns have worse outcomes, so we need to investigate if they need different treatments. Urologists should be aware of these growth patterns and their clinical impact. 01 juli 2023

Published
2023

50. Reply to Andreas Boehle, Frank Kahmann, Thomas Oliver Henkel, Joerg Zimmermann and Stefan Machten’s to the Letter to the editor Re: results of a randomized trial of treatment modalities in patients with low or early-intermediate risk prostate cancer (PREFERE trial)

Author

Wiegel, Thomas, Albers, Peter, Bartkowiak, Detlef, Bussar-Maatz, Roswitha, Härter, Martin, Kristiansen, Glen, Martus, Peter, Wellek, Stefan, Schmidberger, Heinz, Grozinger, Klaus, Renner, Peter, Schneider, Fried, Burmester, Martin, and Stöckle, Michael

Published
2021
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