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1. Bridging the gap: financing health promotion and disease prevention in Indonesia

Author: Ahmad Fuady, Mariska Anindhita, Matsna Haniifah, Abdillah Ahsan, Agus Sugiharto, Marinda Asiah Nuril Haya, Trevino Pakasi, Dian Kusuma, Dewi Amila Solikha, Pungkas Bahjuri Ali, and Indah Suci Widyahening
Subjects: Health system, Health financing, Community health volunteer, Health promoter, Public aspects of medicine, RA1-1270
Abstract: Abstract Background Spending on preventive care in low- and middle-income countries (LMICs), including Indonesia, is much lower than spending on curative care. There has been a pressing need to develop a clear pathway to increase spending on preventive care. This study aimed to assess the current financing landscape for health promotion and disease prevention in Indonesia and, subsequently, to develop a framework and recommendations for future health promotion financing in the country. Methods We adopted a mixed-method approach to gather information from all relevant stakeholders from December 2022 to June 2023. For the qualitative approach, we conducted (a) in-depth interviews (IDIs) and (b) focus group discussions (FGDs) with government officials at national and district levels, academics, professional organizations, healthcare workers in primary healthcare centres (PHCs), community health volunteers, non governmental organizations and private companies. For the quantitative approach, we applied a national online survey to healthcare workers involved in health promotion in PHCs. IDIs and FGDs were conducted with purposefully selected resource persons at the national level, five selected districts across Indonesia, and within 15 primary health offices and their communities. All qualitative data were recorded, transcribed, coded, interpreted, and then triangulated with national survey findings to develop the financing framework. Results We identified gaps between the theory and practice of health promotion and disease prevention. These included the limited scope of health promotion initiatives, lack of direction and coordination between ministries, agencies and government levels, limited availability and capacity of health promoters, various yet uncoordinated funding resources and inflexibility in using the funds. To bridge the gap, the framework we developed suggests strengthening the legal and regulatory basis, strategically prioritizing financing arrangements, promoting evidence-based health promotion activities, developing the capacity of health promoters, enhancing the health financing information system and improving monitoring and evaluation. Conclusions Identified gaps and challenges in health promotion and disease prevention initiatives inform the development of our framework for future health promotion financing. This framework assists the national government in organizing national health promotion financing strategies and potentially serves as a valuable model for other LMICs.
Published: 2024
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2. Mechanism of elevated LH/FSH ratio in lean PCOS revisited: a path analysis

Author: Pratama, Gita, Wiweko, Budi, Asmarinah, Widyahening, Indah S., Andraini, Trinovita, Bayuaji, Hartanto, and Hestiantoro, Andon
Published: 2024
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3. Bridging the gap: financing health promotion and disease prevention in Indonesia

Author: Fuady, Ahmad, Anindhita, Mariska, Haniifah, Matsna, Ahsan, Abdillah, Sugiharto, Agus, Haya, Marinda Asiah Nuril, Pakasi, Trevino, Kusuma, Dian, Solikha, Dewi Amila, Ali, Pungkas Bahjuri, and Widyahening, Indah Suci
Published: 2024
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4. Predicting the incidence of recurrent positive exercise stress tests among civilian pilots: a retrospective cohort study [version 1; peer review: awaiting peer review]

Author: Voltha Herry, Indah Suci Widyahening, Ferdi Afian, Ika Prasetya Wijaya, Boon-How Chew, and Dewi Sumaryani Soemarko
Subjects: Research Article, Articles, coronary artery disease, risk factors, airline pilot, electrocardiography
Abstract: * Background A positive exercise stress test (EST) is common among pilots, and it may indicate a greater risk of coronary artery disease (CAD). This study aimed to determine the incidence of recurrently positive EST and their predictors among civilian pilots in Indonesia. Methods This was a retrospective cohort study among civilian pilots who had the first positive EST test between January 2019 and June 2020 at the Aviation Medical Center, Jakarta. The data were retrieved from medical records. Subjects were included if there were data on subsequent ESTs at 6 and 12 months. Risk factors included total flight hours (TFH) in the last 6 months, license type, aircraft cabin pressurization system, flying limitation such as multicrew, cardiac intervention, age, smoking habit, family history of coronary artery disease, body mass index, blood pressure levels, lipid profile, and fasting blood glucose. Results Eighty-seven pilots were included; 54 of them (62.1%) had recurrent positive ESTs. All subjects were men, and the median age was 51 (range 40-64) years. Independent predictors of recurrent positive ESTs were age 60-65 years (adjusted odds ratio [OR adj]: 5.1, 95% CI: 1.12–23.16, p= 0.035), a TFH of > 275 hours (OR adj 5.1, 95% CI: 1.28–20.65, p= 0.021), and dyslipidemia (OR adj: 4.2 95% CI: 1.468–12.275, p=0.015). Having these three risk factors increased the probability of a recurrent positive EST up to 100%. Conclusion The incidence of recurrently positive ESTs among civilian pilots in Indonesia was high. Airlines may want to implement a more aggressive health policy for the prevention of cardiovascular diseases among their pilots.
Published: 2024
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5. Mechanism of elevated LH/FSH ratio in lean PCOS revisited: a path analysis

Author: Gita Pratama, Budi Wiweko, Asmarinah, Indah S. Widyahening, Trinovita Andraini, Hartanto Bayuaji, and Andon Hestiantoro
Subjects: Dynorphin, Kisspeptin, Neurokinin B, AMH, FAI, HOMA-IR, Medicine, Science
Abstract: Abstract Polycystic ovary syndrome (PCOS) is the most common endocrine disorder affecting 5–20% of reproductive-age women. However, the treatment of PCOS is mainly based on symptoms and not on its pathophysiology. Neuroendocrine disturbance, as shown by an elevated LH/FSH ratio in PCOS patients, was thought to be the central mechanism of the syndrome, especially in lean PCOS. LH and FSH secretion are influenced by GnRH pulsatility of GnRH neurons in the hypothalamus. Kisspeptin is the main regulator of GnRH secretion, whereas neurokinin B (NKB) and dynorphin regulate kisspeptin secretion in KNDy neurons. This study aims to deepen the understanding of the neuroendocrine disorder in lean PCOS patients and its potential pathophysiology-based therapy. A cross-sectional study was performed at Dr. Cipto Mangunkusumo Kencana Hospital and the IMERI UI HRIFP cluster with 110 lean PCOS patients as subjects. LH, FSH, LH/FSH ratio, kisspeptin, NKB, dynorphin, leptin, adiponectin, AMH, fasting blood glucose, fasting insulin, HOMA-IR, testosterone, and SHBG were measured. Bivariate and path analyses were performed to determine the relationship between variables. There was a negative association between dynorphin and kisspeptin, while NKB levels were not associated with kisspeptin. There was no direct association between kisspeptin and the LH/FSH ratio; interestingly, dynorphin was positively associated with the LH/FSH ratio in both bivariate and pathway analyses. AMH was positively correlated with the LH/FSH ratio in both analyses. Path analysis showed an association between dynorphin and kisspeptin levels in lean PCOS, while NKB was not correlated with kisspeptin. Furthermore, there was a correlation between AMH and the LH/FSH ratio, but kisspeptin levels did not show a direct significant relationship with the LH/FSH ratio. HOMA-IR was negatively associated with adiponectin levels and positively associated with leptin and FAI levels. In conclusion, AMH positively correlates with FAI levels and is directly associated with the LH/FSH ratio, showing its important role in neuroendocrinology in lean PCOS. From the path analysis, AMH was also an intermediary variable between HOMA-IR and FAI with the LH/FSH ratio. Interestingly, this study found a direct positive correlation between dynorphin and the LH/FSH ratio, while no association between kisspeptin and the LH/FSH ratio was found. Further research is needed to investigate AMH and dynorphin as potential therapeutic targets in the management of lean PCOS patients.
Published: 2024
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6. Body Composition Parameters, Adiponectin, Leptin and Adiponectin/Leptin Ratio are Correlated with LH/FSH Ratio in Women with PCOS but not in Women without PCOS

Author: Gita Pratama, Budi Wiweko, Asmarinah, Indah Suci Widyahening, Trinovita Andraini, Hartanto Bayuaji, and Andon Hestiantoro
Subjects: Gynecology and obstetrics, RG1-991
Abstract: Objective: To investigate the correlation between body composition parameters, adiponectin, leptin and the adiponectin/leptin ratio and the LH/FSH ratio in women with polycystic ovary syndrome (PCOS). Methods: A cross-sectional study was conducted at Reproductive Cluster Yasmin, Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia, with sixty women with PCOS and sixty healthy women as controls (matched for age and BMI). Body composition parameters, including body weight, body mass index (BMI), waist circumference (WC), waist to hip ratio (WHR), percent body fat (PBF), visceral fat area (VFA), percent subcutaneous fat (PSF) and skeletal muscle mass (SMM), were measured; levels of fasting glucose, fasting insulin, testosterone, and sex hormone binding globulin (SHBG) were measured; and homeostatic model assessment for insulin resistance (HOMA-IR) values, anti-Mullerian hormone (AMH), free androgen index (FAI), Ferriman-Gallwey (FG) score, adiponectin levels, leptin levels, adiponectin/leptin ratio, LH, FSH and LH/FSH ratio were measured. Results: Body composition parameters (body weight, BMI, WC, WHR, PBF, VFA, PSF, SMM) were not significantly different between women with PCOS and controls. Fasting insulin (P
Published: 2024
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7. Association between spinopelvic alignment and the development of degenerative spondylolisthesis: a systematic review and meta-analysis

Author: Rahyussalim, Ahmad Jabir, Widyahening, Indah Suci, Belantara, Latsarizul Alfariq Senja, and Canintika, Anissa Feby
Published: 2023
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8. General and abdominal adiposity and hypertension in eight world regions: a pooled analysis of 837 population-based studies with 7·5 million participants

Author: Zhou, Bin, Bennett, James E, Wickham, Aidan P, Singleton, Rosie K, Mishra, Anu, Carrillo-Larco, Rodrigo M, Ikeda, Nayu, Jain, Lakshya, Barradas-Pires, Ana, Heap, Rachel A, Lhoste, Victor PF, Sheffer, Kate E, Phelps, Nowell H, Rayner, Archie W, Gregg, Edward W, Woodward, Mark, Stevens, Gretchen A, Iurilli, Maria LC, Danaei, Goodarz, Di Cesare, Mariachiara, Aguilar-Salinas, Carlos A, Ahmad, Noor Ani, Bovet, Pascal, Chen, Zhengming, Damasceno, Albertino, Filippi, Sarah L, Janszky, Imre, Kengne, Andre P, Khang, Young-Ho, Khunti, Kamlesh, Laxmaiah, Avula, Lim, Lee-Ling, Lissner, Lauren, Margozzini, Paula, Mbanya, Jean Claude N, McGarvey, Stephen T, Shaw, Jonathan E, Söderberg, Stefan, Soto-Mota, Luis Adrián, Wang, Junyang, Zaccardi, Francesco, Abarca-Gómez, Leandra, Abbasi-Kangevari, Mohsen, Abdrakhmanova, Shynar, Abdul Ghaffar, Suhaila, Abdul Rahim, Hanan F, Abdurrahmonova, Zulfiya, Abu-Rmeileh, Niveen M, Acosta-Cazares, Benjamin, Adam, Ishag, Adamczyk, Marzena, Aekplakorn, Wichai, Agdeppa, Imelda A, Aghazadeh-Attari, Javad, Agyemang, Charles, Ahmad, Mohamad Hasnan, Ahmadi, Ali, Ahmadi, Naser, Ahmadi, Nastaran, Ahmed, Soheir H, Ahrens, Wolfgang, Aitmurzaeva, Gulmira, Ajlouni, Kamel, Al-Hazzaa, Hazzaa M, Al-Hinai, Halima, Al-Lawati, Jawad A, Al-Raddadi, Rajaa, Al Asfoor, Deena, Al Hourani, Huda M, Alarouj, Monira, AlBuhairan, Fadia, AlDhukair, Shahla, Ali, Mohamed M, Alieva, Anna V, Alkandari, Abdullah, Alkhatib, Buthaina M, Aly, Eman, Amarapurkar, Deepak N, Amiano Etxezarreta, Pilar, Amougou, Norbert, Andersen, Lars Bo, Anderssen, Sigmund A, Androutsos, Odysseas, Anjana, Ranjit Mohan, Ansari-Moghaddam, Alireza, Anufrieva, Elena, Aounallah-Skhiri, Hajer, Aris, Tahir, Arku, Raphael E, Arlappa, Nimmathota, Aryal, Krishna K, Assah, Felix K, Assembekov, Batyrbek, Assunção, Maria Cecília F, Auvinen, Juha, Avdičová, Mária, Azad, Kishwar, Azevedo, Ana, Azimi-Nezhad, Mohsen, Azizi, Fereidoun, Bacopoulou, Flora, Bahijri, Suhad, Bajramovic, Izet, Balakrishna, Nagalla, Bamoshmoosh, Mohamed, Banach, Maciej, Bandosz, Piotr, Banegas, José R, Baran, Rafał, Barbagallo, Carlo M, Barbosa Filho, Valter, Barceló, Alberto, Baretić, Maja, Barnoya, Joaquin, Barrera, Lena, Barros, Aluisio JD, Barros, Mauro Virgílio Gomes, Basit, Abdul, Bastos, Joao Luiz, Batieha, Anwar M, Batista, Aline P, Batista, Rosangela L, Battakova, Zhamilya, Baur, Louise A, Bayauli, Pascal M, Bel-Serrat, Silvia, Belavendra, Antonisamy, Ben Romdhane, Habiba, Benedek, Theodora, Benedics, Judith, Benet, Mikhail, Benitez Rolandi, Gilda Estela, Benzeval, Michaela, Bere, Elling, Berger, Nicolas, Bergh, Ingunn Holden, Berkinbayev, Salim, Bernabe-Ortiz, Antonio, Bettiol, Heloísa, Beybey, Augustin F, Bezerra, Jorge, Bhagyalaxmi, Aroor, Bhargava, Santosh K, Bika Lele, Elysée Claude, Bikbov, Mukharram M, Bista, Bihungum, Bjelica, Dusko J, Bjerregaard, Peter, Bjertness, Espen, Bjertness, Marius B, Björkelund, Cecilia, Bloch, Katia V, Blokstra, Anneke, Bo, Simona, Bobak, Martin, Boddy, Lynne M, Boehm, Bernhard O, Boggia, Jose G, Bogova, Elena, Bonaccio, Marialaura, Bonilla-Vargas, Alice, Borghs, Herman, Botomba, Steve, Bourne, Rupert, Boymatova, Khadichamo, Braeckman, Lutgart, Braithwaite, Tasanee, Brajkovich, Imperia, Branca, Francesco, Brenner, Hermann, Brewster, Lizzy M, Briceño, Yajaira, Brinduse, Lacramioara, Bringolf-Isler, Bettina, Brito, Miguel, Brug, Johannes, Bugge, Anna, Buntinx, Frank, Buoncristiano, Marta, Burns, Con, Cabrera de León, Antonio, Caixeta, Roberta B, Cama, Tilema, Can, Günay, Cândido, Ana Paula C, Cañete, Felicia, Capanzana, Mario V, Čapková, Naděžda, Capuano, Eduardo, Capuano, Rocco, Capuano, Vincenzo, Cardoso, Viviane C, Carlsson, Axel C, Casanueva, Felipe F, Casas, Maribel, Censi, Laura, Cervantes‐Loaiza, Marvin, Chamnan, Parinya, Chamukuttan, Snehalatha, Chan, Queenie, Chaturvedi, Nish, Chen, Fangfang, Chen, Huashuai, Chen, Long-Sheng, Cheng, Yiling J, Cheraghian, Bahman, Chetrit, Angela, Chikova-Iscener, Ekaterina, Chinapaw, Mai JM, Chinnock, Anne, Chiolero, Arnaud, Chirita-Emandi, Adela, Chirlaque, María-Dolores, Chong, Chean Lin, Christofaro, Diego G, Chudek, Jerzy, Cifkova, Renata, Cirillo, Massimo, Claessens, Frank, Clare, Philip, Cohen, Emmanuel, Confortin, Susana C, Coppinger, Tara C, Cortés, Lilia Yadira, Cosmin, Cojocaru R, Costanzo, Simona, Cowan, Melanie J, Cowell, Chris, Crampin, Amelia C, Cross, Amanda J, Crujeiras, Ana B, Cruz, Juan J, Cucu, Alexandra M, Cureau, Felipe V, Cuschieri, Sarah, D'Arrigo, Graziella, d'Orsi, Eleonora, da Silva-Ferreira, Haroldo, Dahm, Christina C, Dallongeville, Jean, Dankner, Rachel, Davletov, Kairat, de Assis Guedes de Vasconcelos, Francisco, de Assis, Maria Alice Altenburg, De Bacquer, Dirk, De Bacquer, Jaco, de Bont, Jeroen, De Curtis, Amalia, de Fragas Hinnig, Patrícia, de Gaetano, Giovanni, De Henauw, Stefaan, De Miguel-Etayo, Pilar, de Oliveira, Paula Duarte, de Paiva, Karina Mary, De Ridder, Karin, de Valois Correia Júnior, Marco Aurélio, Deepa, Mohan, DeGennaro, Vincent Jr, Demarest, Stefaan, Dennison, Elaine, Deschamps, Valérie, Dhimal, Meghnath, Díez Ripollés, María Pilar, Dika, Zivka, Djalalinia, Shirin, Dominguez, Liria, Donati, Maria Benedetta, Donfrancesco, Chiara, Dong, Guanghui, Donoso, Silvana P, Dorobantu, Maria, Dörr, Marcus, Dragano, Nico, Drygas, Wojciech, Du, Shufa, Duante, Charmaine A, Duboz, Priscilla, Duda, Rosemary B, Duleva, Vesselka L, Dushpanova, Anar, Dyussupova, Azhar, Dziankowska-Zaborszczyk, Elzbieta, Ebrahimi, Narges, Echeverría, Guadalupe, Eddie, Ricky, Eftekhar, Ebrahim, Efthymiou, Vasiliki, Egbagbe, Eruke E, Eghtesad, Sareh, Ekelund, Ulf, El-Khateeb, Mohammad, El Ati, Jalila, Elosua, Roberto, Enang, Ofem, Erasmus, Rajiv T, Erem, Cihangir, Ergor, Gul, Eriksen, Louise, Eriksson, Johan G, Escobedo-de la Peña, Jorge, Esmaeili, Ali, Evans, Roger G, Fakhradiyev, Ildar, Fakhretdinova, Albina A, Fall, Caroline H, Faramarzi, Elnaz, Farjam, Mojtaba, Farzadfar, Farshad, Farzi, Yosef, Fattahi, Mohammad Reza, Fawwad, Asher, Felix-Redondo, Francisco J, Ferguson, Trevor S, Fernandes, Romulo A, Fernández-Bergés, Daniel, Fernando, Desha R, Ferrante, Daniel, Ferrari, Gerson, Ferrari, Marika, Ferreccio, Catterina, Ferrer, Eldridge, Figueiró, Thamara Hubler, Fijalkowska, Anna, Fink, Günther, Fisberg, Mauro, Forsner, Maria, Fottrell, Edward F, Fouad, Heba M, Francis, Damian K, Frontera, Guillermo, Fuchs, Flavio D, Fuchs, Sandra C, Furdela, Viktoriya, Furusawa, Takuro, Gabriela, Stefan Adela, Gaciong, Zbigniew, Galán Cuesta, Manuel, Galbarczyk, Andrzej, Galcheva, Sonya V, Galfo, Myriam, Garcia-de-la-Hera, Manoli, Garcia, Pablo, Garnett, Sarah P, Gasull, Magda, Gazzinelli, Andrea, Gehring, Ulrike, Gerdts, Eva, Ghaderi, Ebrahim, Ghamari, Seyyed-Hadi, Ghanbari, Ali, Ghasemi, Erfan, Gheorghe-Fronea, Oana-Florentina, Ghimire, Anup, Gialluisi, Alessandro, Giampaoli, Simona, Gianfagna, Francesco, Gironella, Glen, Giwercman, Aleksander, Gkiouras, Konstantinos, Glushkova, Natalya, Godara, Ramesh, Godos, Justyna, Goldberg, Marcel, Gómez, Georgina, Gómez Gómez, Jesús Humberto, Gomez, Luis F, Gómez, Santiago F, Gomula, Aleksandra, Gonçalves Cordeiro da Silva, Bruna, Gonçalves, Helen, Gonçalves, Mauer, González-Alvarez, Ana D, Gonzalez-Chica, David A, González-Gil, Esther M, Gonzalez-Gross, Marcela, González-Rivas, Juan P, Gonzalez, Angel R, Gottrand, Frederic, Grafnetter, Dušan, Grajda, Aneta, Grammatikopoulou, Maria G, Grodzicki, Tomasz, Grøholt, Else Karin, Grøntved, Anders, Guajardo, Viviana, Guallar-Castillón, Pilar, Guerchet, Maëlenn, Guerrero, Ramiro, Guimaraes, Andre L, Gujral, Unjali P, Gulliford, Martin C, Gunter, Marc J, Gupta, Rajeev, Gureje, Oye, Gurinović, Mirjana A, Gurzkowska, Beata, Gutierrez, Laura, Gwee, Xinyi, Haghshenas, Rosa, Hakimi, Hamid, Halkjær, Jytte, Hambleton, Ian R, Hamzeh, Behrooz, Hanekom, Willem A, Hange, Dominique, Hanif, Abu AM, Hantunen, Sari, Hao, Jie, Hardman, Carla Menêses, Hardy, Louise, Hari Kumar, Rachakulla, Harooni, Javad, Hashemi-Shahri, Seyed Mohammad, Hassapidou, Maria, Hata, Jun, Haugsgjerd, Teresa, Heinen, Mirjam, Hendriks, Marleen Elisabeth, Henrique, Rafael dos Santos, Henriques, Ana, Hernandez Cadena, Leticia, Herrala, Sauli, Herrera-Cuenca, Marianella, Herrera, Victor M, Herter-Aeberli, Isabelle, Herzig, Karl-Heinz, Heshmat, Ramin, Hill, Allan G, Ho, Sai Yin, Holdsworth, Michelle, Homayounfar, Reza, Homs, Clara, Hoogendijk, Emiel O, Horimoto, Andrea RVR, Hormiga, Claudia M, Horta, Bernardo L, Houti, Leila, Howitt, Christina, Htay, Thein Thein, Htet, Aung Soe, Htike, Maung Maung Than, Huerta, José María, Huhtaniemi, Ilpo Tapani, Huiart, Laetitia, Huidumac Petrescu, Constanta, Huisman, Martijn, Husseini, Abdullatif, Huybrechts, Inge, Hwalla, Nahla, Iacoviello, Licia, Iakupova, Ellina M, Iannone, Anna G, Igland, Jannicke, Ijoma, Chinwuba, Iotova, Violeta, Irazola, Vilma E, Ishida, Takafumi, Isiguzo, Godsent C, Islam, Muhammad, Islam, Sheikh Mohammed Shariful, Islek, Duygu, Ittermann, Till, Ivanova-Pandourska, Ivaila Y, Iwasaki, Masanori, Jääskeläinen, Tuija, Jackson, Rod T, Jaddou, Hashem Y, Jadoul, Michel, Jafar, Tazeen, Jan, Nataša, Janus, Edward, Jarani, Juel, Jarnig, Gerald, Jarvelin, Marjo-Riitta, Jasienska, Grazyna, Jelaković, Ana, Jelaković, Bojan, Jha, Anjani Kumar, Jimenez, Ramon O, Jöckel, Karl-Heinz, Joffres, Michel, Jokelainen, Jari J, Jonas, Jost B, Joshi, Pradeep, Joshi, Rohina, Josipović, Josipa, Joukar, Farahnaz, Jóźwiak, Jacek J, Juolevi, Anne, Juresa, Vesna, Jureša, Vesna, Kaaks, Rudolf, Kaducu, Felix O, Kadvan, Agnes L, Kafatos, Anthony, Kajantie, Eero O, Kakutia, Natia, Kállayová, Daniela, Kalmatayeva, Zhanna, Kalter-Leibovici, Ofra, Kannan, Srinivasan, Kapantais, Efthymios, Karaglani, Eva, Karakosta, Argyro, Karki, Khem B, Kassi Anicet, Adoubi, Katibeh, Marzieh, Katulanda, Prasad, Katzmarzyk, Peter T, Kauhanen, Jussi, Kazakbaeva, Gyulli M, Kaze, François F, Ke, Calvin, Keinänen-Kiukaanniemi, Sirkka, Kelishadi, Roya, Kelleher, Cecily, Kemper, Han CG, Keramati, Maryam, Kersting, Mathilde, Khader, Yousef Saleh, Khaledifar, Arsalan, Khalili, Davood, Kheiri, Bahareh, Kheradmand, Motahareh, Khosravi, Alireza, Kiechl-Kohlendorfer, Ursula, Kiechl, Sophia J, Kiechl, Stefan, Kim, Hyeon Chang, Klakk, Heidi, Klanarong, Suntara, Klanova, Jana, Klimek, Magdalena, Knoflach, Michael, Kobel, Susanne, Koirala, Bhawesh, Kolle, Elin, Kolsteren, Patrick, König, Jürgen, Korpelainen, Raija, Korrovits, Paul, Korzycka, Magdalena, Kos, Jelena, Koskinen, Seppo, Koussoh Simone, Malik, Kovács, Éva, Kovalskys, Irina, Kowlessur, Sudhir, Koziel, Slawomir, Kratenova, Jana, Kratzer, Wolfgang, Kriemler, Susi, Kristensen, Peter Lund, Krizan, Helena, Kroker-Lobos, Maria F, Krokstad, Steinar, Kruger, Herculina S, Kruger, Ruan, Kryst, Łukasz, Kubinova, Ruzena, Kujala, Urho M, Kujundzic, Enisa, Kulaga, Zbigniew, Kulimbet, Mukhtar, Kumari, Meena, Kunešová, Marie, Kurjata, Pawel, Kyobutungi, Catherine, La, Quang Ngoc, Labadarios, Demetre, Lachat, Carl, Lai, Daphne, Laid, Youcef, Lall, Lachmie, Landaeta Jimenez, Maritza, Landais, Edwige, Lankila, Tiina, Lanska, Vera, Lappas, Georg, Larijani, Bagher, Lateva, Mina P, Latt, Tint Swe, Laurenzi, Martino, Lazo-Porras, Maria, Le Coroller, Gwenaëlle, Le Nguyen Bao, Khanh, Lehtimäki, Terho, Lemogoum, Daniel, Leong, Elvynna, Leszczak, Justyna, Leung, Gabriel M, Li, Yanping, Liivak, Merike, Lim, Charlie, Lim, Wei-Yen, Lima-Costa, M Fernanda, Lin, Hsien-Ho, Lind, Lars, Litwin, Mieczyslaw, Liu, Liping, Liu, Xiaotian, Longo Abril, Guadalupe, Lopes, Oscar, Lopez-Garcia, Esther, López-Gil, José Francisco, Lopez, Tania, Lozano, José Eugenio, Lukrafka, Janice L, Luksiene, Dalia, Lundqvist, Annamari, Lunet, Nuno, Lunogelo, Charles, Lustigová, Michala, M'Buyamba-Kabangu, Jean-René, Machado-Coelho, George LL, Machado-Rodrigues, Aristides M, Macia, Enguerran, Madar, Ahmed A, Maestre, Gladys E, Maggi, Stefania, Magliano, Dianna J, Magnacca, Sara, Magriplis, Emmanuella, Mahasampath, Gowri, Maire, Bernard, Makdisse, Marcia, Malekpour, Mohammad-Reza, Malekzadeh, Fatemeh, Malekzadeh, Reza, Mallikharjuna Rao, Kodavanti, Malyutina, Sofia, Maniego, Lynell V, Manios, Yannis, Mann, Jim I, Mansour-Ghanaei, Fariborz, Manzato, Enzo, Mapatano, Mala Ali, Maria-Magdalena, Rosu, Mariño, Joany, Markaki, Anastasia, Marques, Larissa Pruner, Marrugat, Jaume, Martorell, Reynaldo, Maruszczak, Katharina, Masala, Giovanna, Mascarenhas, Luis P, Masimango Imani, Mannix, Masinaei, Masoud, Mathiesen, Ellisiv B, Matijasevich, Alicia, Matłosz, Piotr, Matsha, Tandi E, Matsudo, Victor, Matteo, Giletta, Maulik, Pallab K, Mavrogianni, Christina, Mc Donald Posso, Anselmo J, McFarlane, Shelly R, McLean, Rachael M, Mediene Benchekor, Sounnia, Mehlig, Kirsten, Mehrparvar, Amir Houshang, Melgarejo, Jesus D, Méndez, Fabián, Mendivil, Carlos O, Mendoza Montano, Carlos, Menezes, Ana Maria B, Mensink, Gert BM, Mereke, Alibek, Meshram, Indrapal I, Meto, Diane T, Meyer, Haakon E, Mi, Jie, Miłkowska, Karolina, Miller, Jody C, Milushkina, Olga, Minderico, Cláudia S, Mini, GK, Miquel, Juan Francisco, 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Published: 2024
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9. Worldwide trends in underweight and obesity from 1990 to 2022: a pooled analysis of 3663 population-representative studies with 222 million children, adolescents, and adults

Author: Phelps, Nowell H, Singleton, Rosie K, Zhou, Bin, Heap, Rachel A, Mishra, Anu, Bennett, James E, Paciorek, Christopher J, Lhoste, Victor PF, Carrillo-Larco, Rodrigo M, Stevens, Gretchen A, Rodriguez-Martinez, Andrea, Bixby, Honor, Bentham, James, Di Cesare, Mariachiara, Danaei, Goodarz, Rayner, Archie W, Barradas-Pires, Ana, Cowan, Melanie J, Savin, Stefan, Riley, Leanne M, Aguilar-Salinas, Carlos A, Baker, Jennifer L, Barkat, Amina, Bhutta, Zulfiqar A, Branca, Francesco, Caixeta, Roberta B, Cuschieri, Sarah, Farzadfar, Farshad, Ganapathy, Shubash, Ikeda, Nayu, Iotova, Violeta, Kengne, Andre P, Khang, Young-Ho, Laxmaiah, Avula, Lin, Hsien-Ho, Ma, Jun, Mbanya, Jean Claude N, Miranda, J Jaime, Pradeepa, Rajendra, Rodríguez-Artalejo, Fernando, Sorić, Maroje, Turley, Maria, Wang, Limin, Webster-Kerr, Karen, Aarestrup, Julie, Abarca-Gómez, Leandra, Abbasi-Kangevari, Mohsen, Abdeen, Ziad A, Abdrakhmanova, Shynar, Abdul Ghaffar, Suhaila, Abdul Rahim, Hanan F, Abdurrahmonova, Zulfiya, Abu-Rmeileh, Niveen M, Abubakar Garba, Jamila, Acosta-Cazares, Benjamin, Adam, Ishag, Adamczyk, Marzena, Adams, Robert J, Adu-Afarwuah, Seth, Aekplakorn, Wichai, Afsana, Kaosar, Afzal, Shoaib, Agbor, Valirie N, Agdeppa, Imelda A, Aghazadeh-Attari, Javad, Ågren, Åsa, Aguenaou, Hassan, Agyemang, Charles, Ahmad, Mohamad Hasnan, Ahmad, Noor Ani, Ahmadi, Ali, Ahmadi, Naser, Ahmadi, Nastaran, Ahmed, Imran, Ahmed, Soheir H, Ahrens, Wolfgang, Aitmurzaeva, Gulmira, Ajlouni, Kamel, Al-Hazzaa, Hazzaa M, Al-Hinai, Halima, Al-Lahou, Badreya, Al-Lawati, Jawad A, Al-Raddadi, Rajaa, Al Asfoor, Deena, Al Hourani, Huda M, Al Qaoud, Nawal M, Alarouj, Monira, AlBuhairan, Fadia, AlDhukair, Shahla, Aldwairji, Maryam A, Alexius, Sylvia, Ali, Mohamed M, Alieva, Anna V, Alkandari, Abdullah, Alkerwi, Ala'a, Alkhatib, Buthaina M, Allin, Kristine, Alomary, Shaker A, Alomirah, Husam F, Alshangiti, Arwa M, Alvarez-Pedrerol, Mar, Aly, Eman, Amarapurkar, Deepak N, Amiano Etxezarreta, Pilar, Amoah, John, Amougou, 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Rezaianzadeh, Abbas, Rho, Yeunsook, Ribas-Barba, Lourdes, Ribeiro, Robespierre, Riboli, Elio, Rigo, Fernando, Rigotti, Attilio, Rinaldo, Natascia, Rinke de Wit, Tobias F, Risérus, Ulf, Rito, Ana I, Ritti-Dias, Raphael M, Rivera, Juan A, Roa, Reina G, Robinson, Louise, Roccaldo, Romana, Rodrigues, Daniela, Rodriguez-Perez, María del Cristo, Rodríguez-Villamizar, Laura A, Rodríguez, Andrea Y, Roggenbuck, Ulla, Rohloff, Peter, Rohner, Fabian, Rojas-Martinez, Rosalba, Rojroongwasinkul, Nipa, Romaguera, Dora, Romeo, Elisabetta L, Rosario, Rafaela V, Rosengren, Annika, Rouse, Ian, Rouzier, Vanessa, Roy, Joel GR, Ruano, Maira H, Rubinstein, Adolfo, Rühli, Frank J, Ruidavets, Jean-Bernard, Ruiz-Betancourt, Blanca Sandra, Ruiz-Castell, Maria, Ruiz Moreno, Emma, Rusakova, Iuliia A, Rusek, Wojciech, Russell Jonsson, Kenisha, Russo, Paola, Rust, Petra, Rutkowski, Marcin, Saamel, Marge, Saar, Crizian G, Sabanayagam, Charumathi, Sabbaghi, Hamideh, Sacchini, Elena, Sachdev, Harshpal S, Sadjadi, Alireza, Safarpour, Ali Reza, Safi, Sare, Safiri, Saeid, Saghi, Mohammad Hossien, Saidi, Olfa, Saieva, Calogero, Sakata, Satoko, Saki, Nader, Šalaj, Sanja, Salanave, Benoit, Salazar Martinez, Eduardo, Salhanova, Akkumis, Salmerón, Diego, Salomaa, Veikko, Salonen, Jukka T, Salvetti, Massimo, Samoutian, Margarita, Sánchez-Abanto, Jose, Sánchez Rodríguez, Inés, Sandjaja, Sans, Susana, Santa-Marina, Loreto, Santacruz, Ethel, Santos, Diana A, Santos, Ina S, Santos, Lèlita C, Santos, Maria Paula, Santos, Osvaldo, Santos, Rute, Santos, Tamara R, Saramies, Jouko L, Sardinha, Luis B, Sarrafzadegan, Nizal, Sathish, Thirunavukkarasu, Saum, Kai-Uwe, Savva, Savvas, Savy, Mathilde, Sawada, Norie, Sbaraini, Mariana, Scazufca, Marcia, Schaan, Beatriz D, Schaffrath Rosario, Angelika, Schargrodsky, Herman, Schienkiewitz, Anja, Schindler, Karin, Schipf, Sabine, Schmidt, Börge, Schmidt, Carsten O, Schmidt, Ida Maria, Schneider, Andrea, Schnohr, Peter, Schöttker, Ben, Schramm, Sara, Schramm, Stine, Schröder, Helmut, Schultsz, Constance, Schultz, Gry, Schulze, Matthias B, Schutte, Aletta E, Sebert, Sylvain, Sedaghattalab, Moslem, Selamat, Rusidah, Sember, Vedrana, Sen, Abhijit, Senbanjo, Idowu O, Sepanlou, Sadaf G, Sequera, Guillermo, Serra-Majem, Luis, Servais, Jennifer, Ševčíková, Ľudmila, Sewpaul, Ronel, Shalnova, Svetlana, Shamah-Levy, Teresa, Shamshirgaran, Seyed Morteza, Shanthirani, Coimbatore Subramaniam, Sharafkhah, Maryam, Sharma, Sanjib K, Sharman, Almaz, Shaw, Jonathan E, Shayanrad, Amaneh, Shayesteh, Ali Akbar, Shengelia, Lela, Shi, Zumin, Shibuya, Kenji, Shimizu-Furusawa, Hana, Shimony, Tal, Shiri, Rahman, Shrestha, Namuna, Si-Ramlee, Khairil, Siani, Alfonso, Siantar, Rosalynn, Sibai, Abla M, Sidossis, Labros S, Silitrari, Natalia, Silva, Antonio M, Silva, Caroline Ramos de Moura, Silva, Diego Augusto Santos, Silva, Kelly Samara, Sim, Xueling, Simon, Mary, Simons, Judith, Simons, Leon A, Sjöberg, Agneta, Sjöström, Michael, Skoblina, Elena V, Skoblina, Natalia A, Slazhnyova, Tatyana, Slowikowska-Hilczer, Jolanta, Slusarczyk, Przemysław, Smeeth, Liam, So, Hung-Kwan, Soares, Fernanda Cunha, Sobek, Grzegorz, Sobngwi, Eugène, Sodemann, Morten, Söderberg, Stefan, Soekatri, Moesijanti YE, Soemantri, Agustinus, Sofat, Reecha, Solfrizzi, Vincenzo, Solovieva, Yuliya V, Somi, Mohammad Hossein, Sonestedt, Emily, Song, Yi, Soofi, Sajid, Sørensen, Thorkild IA, Sørgjerd, Elin P, Sossa Jérome, Charles, Soto-Rojas, Victoria E, Soumaré, Aïcha, Sousa-Poza, Alfonso, Sovic, Slavica, Sparboe-Nilsen, Bente, Sparrenberger, Karen, Spencer, Phoebe R, Spinelli, Angela, Spiroski, Igor, Staessen, Jan A, Stamm, Hanspeter, Stang, Andreas, Starc, Gregor, Staub, Kaspar, Stavreski, Bill, Steene-Johannessen, Jostein, Stehle, Peter, Stein, Aryeh D, Steinsbekk, Silje, Stergiou, George S, Stessman, Jochanan, Stevanović, Ranko, Stieber, Jutta, Stöckl, Doris, Stokwiszewski, Jakub, Stoyanova, Ekaterina, Stratton, Gareth, Stronks, Karien, Strufaldi, Maria Wany, Sturua, Lela, Suárez-Medina, Ramón, Suarez-Ortegón, Milton F, Suebsamran, Phalakorn, Sugiyama, Mindy, Suka, Machi, Sulo, Gerhard, Sun, Chien-An, Sun, Liang, Sund, Malin, Sundström, Johan, Sung, Yn-Tz, Sunyer, Jordi, Suriyawongpaisal, Paibul, Sweis, Nabil William G, Swinburn, Boyd A, Sy, Rody G, Sylva, René Charles, Szponar, Lucjan, Tabone, Lorraine, Tai, E Shyong, Takuro, Furusawa, Tambalis, Konstantinos D, Tammesoo, Mari-Liis, Tamosiunas, Abdonas, Tan, Eng Joo, Tang, Xun, Tanrygulyyeva, Maya, Tanser, Frank, Tao, Yong, Tarawneh, Mohammed Rasoul, Tarp, Jakob, Tarqui-Mamani, Carolina B, Taxová Braunerová, Radka, Taylor, Anne, Taylor, Julie, Tchibindat, Félicité, Te Velde, Saskia, Tebar, William R, Tell, Grethe S, Tello, Tania, Tessema, Masresha, Tham, Yih Chung, Thankappan, KR, Theobald, Holger, Theodoridis, Xenophon, Thomas, Nihal, Thorand, Barbara, Thrift, Amanda G, Tichá, Ľubica, Timmermans, Erik J, Tjandrarini, Dwi Hapsari, Tjonneland, Anne, Tolonen, Hanna K, Tolstrup, Janne S, Tomaszewski, Maciej, Topbas, Murat, Topór-Mądry, Roman, Torheim, Liv Elin, Tornaritis, Michael J, Torrent, Maties, Torres-Collado, Laura, Toselli, Stefania, Touloumi, Giota, Traissac, Pierre, Tran, Thi Tuyet-Hanh, Tremblay, Mark S, Triantafyllou, Areti, Trichopoulos, Dimitrios, Trichopoulou, Antonia, Trinh, Oanh TH, Trivedi, Atul, Tshepo, Lechaba, Tsigga, Maria, Tsintavis, Panagiotis, Tsugane, Shoichiro, Tuitele, John, Tuliakova, Azaliia M, Tulloch-Reid, Marshall K, Tullu, Fikru, Tuomainen, Tomi-Pekka, Tuomilehto, Jaakko, Twig, Gilad, Tynelius, Per, Tzala, Evangelia, Tzotzas, Themistoklis, Tzourio, Christophe, Udoji, Nwannedimma, Ueda, Peter, Ugel, Eunice, Ukoli, Flora AM, Ulmer, Hanno, Unal, Belgin, Usupova, Zhamyila, Uusitalo, Hannu MT, Uysal, Nalan, Vaitkeviciute, Justina, Valdivia, Gonzalo, Vale, Susana, Valvi, Damaskini, van Dam, Rob M, van den Born, Bert-Jan, Van der Heyden, Johan, van der Schouw, Yvonne T, Van Herck, Koen, Van Lippevelde, Wendy, Van Minh, Hoang, Van Schoor, Natasja M, van Valkengoed, Irene GM, Vanderschueren, Dirk, Vanuzzo, Diego, Varbo, Anette, Varela-Moreiras, Gregorio, Vargas, Luz Nayibe, Varona-Pérez, Patricia, Vasan, Senthil K, Vasques, Daniel G, Vatasescu, Radu, Vega, Tomas, Veidebaum, Toomas, Velasquez-Melendez, Gustavo, Velika, Biruta, Verloigne, Maïté, Veronesi, Giovanni, Verschuren, WM Monique, Victora, Cesar G, Viegi, Giovanni, Viet, Lucie, Vik, Frøydis N, Vilar, Monica, Villalpando, Salvador, Vioque, Jesus, Viriyautsahakul, Napaphan, Virtanen, Jyrki K, Visser, Marjolein, Visvikis-Siest, Sophie, Viswanathan, Bharathi, Vladulescu, Mihaela, Vlasoff, Tiina, Vocanec, Dorja, Vollenweider, Peter, Völzke, Henry, Vourli, Georgia, Voutilainen, Ari, Vrijheid, Martine, Vrijkotte, Tanja GM, Vuletić, Silvije, Wade, Alisha N, Waldhör, Thomas, Walton, Janette, Wambiya, Elvis OA, Wan Bebakar, Wan Mohamad, Wan Mohamud, Wan Nazaimoon, Wanderley Júnior, Rildo de Souza, Wang, Chongjian, Wang, Huijun, Wang, Ming-Dong, Wang, Ningli, Wang, Qian, Wang, Xiangjun, Wang, Ya Xing, Wang, Ying-Wei, Wannamethee, S Goya, Wareham, Nicholas, Wartha, Olivia, Weber, Adelheid, Wedderkopp, Niels, Weghuber, Daniel, Wei, Wenbin, Weres, Aneta, Werner, Bo, Westbury, Leo D, Whincup, Peter H, Wichstrøm, Lars, Wickramasinghe, Kremlin, Widhalm, Kurt, Widyahening, Indah S, Więcek, Andrzej, Wild, Philipp S, Wilks, Rainford J, Willeit, Johann, Willeit, Peter, Williams, Julianne, Wilsgaard, Tom, Wirth, James P, Wojtyniak, Bogdan, Woldeyohannes, Meseret, Wolf, Kathrin, Wong-McClure, Roy A, Wong, Andrew, Wong, Emily B, Wong, Jyh Eiin, Wong, Tien Yin, Woo, Jean, Woodward, Mark, Wu, Frederick C, Wu, Hon-Yen, Wu, Jianfeng, Wu, Li Juan, Wu, Shouling, Wyszyńska, Justyna, Xu, Haiquan, Xu, Liang, Yaacob, Nor Azwany, Yamborisut, Uruwan, Yan, Li, Yan, Weili, Yang, Ling, Yang, Xiaoguang, Yang, Yang, Yardim, Nazan, Yasuharu, Tabara, Yépez García, Martha, Yiallouros, Panayiotis K, Yngve, Agneta, Yoosefi, Moein, Yoshihara, Akihiro, Yotov, Yoto, You, Qi Sheng, You, San-Lin, Younger-Coleman, Novie O, Yu, Yu-Ling, Yu, Yunjiang, Yusof, Safiah Md, Yusoff, Ahmad Faudzi, Zaccagni, Luciana, Zafiropulos, Vassilis, Zainuddin, Ahmad A, Zakavi, Seyed Rasoul, Zamani, Farhad, Zambon, Sabina, Zampelas, Antonis, Zamrazilová, Hana, Zapata, Maria Elisa, Zargar, Abdul Hamid, Zaw, Ko Ko, Zayed, Ayman A, Zdrojewski, Tomasz, Żegleń, Magdalena, Zejglicova, Kristyna, Zeljkovic Vrkic, Tajana, Zeng, Yi, Zentai, Andrea, Zhang, Bing, Zhang, Luxia, Zhang, Zhen-Yu, Zhao, Dong, Zhao, Ming-Hui, Zhao, Wenhua, Zhecheva, Yanitsa V, Zhen, Shiqi, Zheng, Wei, Zheng, Yingfeng, Zholdin, Bekbolat, Zhou, Maigeng, Zhu, Dan, Zimmet, Paul, Zins, Marie, Zitt, Emanuel, Zocalo, Yanina, Zoghlami, Nada, Zuñiga Cisneros, Julio, Zuziak, Monika, and Ezzati, Majid
Published: 2024
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10. Diagnostic Performance of Urine-based HPV-DNA Test (CerviScan, Bio Farma) as Cervical Cancer Screening Tool in Adult Women

Author: Andrijono Andrijono, Dewi Wulandari, Indah Suci Widyahening, Dicky Mahardhika, Neni Nurainy, Rini Mulia Sari, Indriastuti Soetomo, and Revata Utama
Subjects: Gynecology and obstetrics, RG1-991
Abstract: Objective: Detection of high-risk human papillomavirus (hr-HPV) in urine specimens has been introduced recently and a new local PCR kit has been developed in Indonesia (CerviScan, Bio Farma). The objective of this study was to obtain the accuracy of hr-HPV DNA testing using the new kit (CerviScan, Bio Farma) on urine specimens against the gold standard on cervical swabs. Method: Adult women (aged 20–50 years) underwent routine general check-up or Pap test were enrolled between July and September 2022. Pairs of urine and cervical swab specimens were obtained from all subjects. HPV-DNA tests were performed using the new local PCR kit (CerviScan, Bio Farma) and the standard procedure (COBAS® 6800 HPV, Roche Molecular System). Direct sequencing was added whenever there were dispute results between the two methods. Agreement between both methods was tested using Kappa statistics. Diagnostic performance test was done on CerviScan. Results: A total of 876 women completed the examination. Agreement between CerviScan and COBAS® 6800 was substantial (K=0.662; p
Published: 2023
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11. General versus spinal anesthesia in percutaneous nephrolithotomy: A systematic review and meta-analysis [version 2; peer review: 1 approved, 1 not approved]

Author: Rinaldo Indra Rachman, Ponco Birowo, Ghifari Nurullah, Prof. Sung Yong Cho, Widi Atmoko, Indah Suci Widyahening, and Nur Rasyid
Subjects: Systematic Review, Articles, PCNL, Spinal Anesthesia, General Anesthesia, Complication, Stone-free Rate
Abstract: Background: Percutaneous nephrolithotomy (PCNL) is the preferred treatment for the removal of large kidney stones, sized >20 mm. However, there is still an ongoing debate concerning the best anesthesia for PCNL. This study aimed to compare the efficacy and safety between general and spinal anesthesia for PCNL. Methods: A systematic review and meta-analysis study. A systematic, electronic literature search was performed in several databases, including PubMed, Scopus, and Google Scholar until July 1 st, 2022. The quality of the articles was examined using Crombie's Items (for non-randomized controlled trials (RCTs)) and Jadad Scale (for RCTs). The outcomes assessed were operation time, fluoroscopy time, length of stay, stone-free rate, overall complication rate, specific postoperative complications, cost, pain score, and postoperative analgesic requirement. The article selection was reported based on the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines. We assessed four RCTs and eight retrospective studies. Meta-analysis of selected studies was performed using the Review Manager 5.3. Results: General anesthesia resulted in fewer Clavien–Dindo grade II (OR: 0.68; 95% CI: 0.49 – 0.94; p=0.02), major complications (OR: 0.65; 95% CI: 0.45 – 0.94; p=0.02, and lower transfusion rates (OR: 0.70; 95% CI: 0.53 – 0.94; p=0.02). Whereas spinal anesthesia resulted in faster operation time (Mean Difference: -12.98; 95% CI: -20.56 – -5.41; p Conclusions: Each method of anesthesia has its own advantages and disadvantages. The final choice between general and spinal anesthesia should be based on the patient's condition and surgical team preference.
Published: 2023
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12. Knowledge, attitudes, and practices regarding male infertility: A cross-sectional study among infertile couples visiting fertility clinics in Indonesia’s urban areas [version 1; peer review: 1 approved with reservations]

Author: Yusuf Mushlih, Imam Adli, Leo Alfath Araysi, Kemal Akbar Suryoadji, Rinaldo Indra Rachman, Ghifari Nurullah, Roberto Bagaskara Indy Christanto, Missy Savira, Rupin Shah, Ashok Agarwal, Indah Suci Widyahening, Gita Pratama, Gede Wirya Kusuma Duarsa, Ricky Adriansjah, Dyandra Parikesit, Widi Atmoko, Nur Rasyid, and Ponco Birowo
Subjects: Research Article, Articles, male infertility, infertile couples, infertility knowledge, fertility, stigma, misperception
Abstract: Background: In many countries, the stereotype that women are to blame for infertility in relationships remains prevalent, even though approximately half of the cases are caused by male factors. This study aimed to determine the knowledge, attitudes, and practices of infertile couples in urban areas with regard to male infertility. Methods: A web-based survey was conducted among infertile couples who visited fertility clinics in three cities in Indonesia. Sociodemographic information and knowledge, attitudes, and practices regarding male infertility were obtained through self-reported questionnaires. Results: A total of 378 participants completed the questionnaire (210 men and 177 women); 66.9% had good knowledge, 72.5% had positive attitudes, and 70.1% had good practices related to male infertility. Knowledge moderately correlated with attitudes ( r = 0.280, p = 0.016), whereas the correlation with practices was not significant ( r = 0.140, p = 0.186). The correlation between attitudes and practices was moderate ( r = 0.251, p = 0.031). Among all participants, 82% visited an obstetrician-gynecologist first. A total of 39.9% of fertility examinations were conducted first on the wife, 11.4% on the husband, and 48.7% on both. Conclusion: Most participants in our study at fertility clinics in urban areas visited an obstetrician-gynecologist first rather than a urologist, despite having good knowledge, attitudes, and practices regarding male infertility. The government needs to conduct health education and further public health efforts regarding male infertility to reduce the negative stigma and misperceptions about infertility in society.
Published: 2023
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13. #278 : Relationship Between Level Expression of miRNA-191 and miRNA-548c-3p in Embryo Culture Medium and Embryo Chromosomal Status

Author: Riyan Hari Kurniawan, Raden Muharam, Indah Suci Widyahening, Pritta Ameilia Iffanolida, and Budi Wiweko
Subjects: Chromosomal status, miRNA-191, miRNA-548c-3p, IVF, Reproduction, QH471-489
Abstract: Background: microRNA (miRNA) is expressed by the human embryos and shows the difference between euploid and aneuploid embryos. miRNA which is secreted in culture media is expected to be a biomarker for embryo chromosomal status testing. This research aims to analyse the relationship between expression level of miRNA-191 and miRNA-548c-3p in embryo culture media and embryo chromosomal status. Methods: This cross-sectional research was done on 30 embryos from 12 patients aged 28-40 years old who underwent an in vitro fertilization (IVF) program in three clinics. Embryos were cultured until blastocyst stage. PGT-A was done after blastocyst biopsy on day 5 or 6, and chromosomal analysis was done using the NGS method. The expression levels of miRNA-191 and miRNA-548c-3p were analysed from culture media sample of the embryo using qPCR method. Then the relationship between miRNA-191 and miRNA-548c-3p expression level with embryo chromosomal status was analysed. Results: There is no significant difference in subjects’ characteristics between the euploid and aneuploid embryo groups (p>0.05) [Table 1]. There is no significant difference in the expression level of miRNA-191 of the euploid and aneuploid embryo groups. (Median quantification 8.69 vs 1.064 with p=0.351) [Table 2]. There is no significant difference in the expression level of miRNA-548c-3p of the euploid and aneuploid embryo groups. (Median quantification 9.06 vs 6.635 with p=0.709) [Table 3]. Conclusions: miRNA-191 expression level and miRNA-548c-3p expression level has no relationship with embryo chromosomal status. The level expression of miRNA-191 and miRNA-548c-3p in embryo culture has not been a good biomarker candidate for embryo chromosomal status.
Published: 2023
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14. #279 : The Relationship Between Maternal Age and the Chromosomal Status of the Embryo

Author: Riyan Hari Kurniawan, Raden Muharam, Indah Suci Widyahening, Pritta Ameilia Iffanolida, and Budi Wiweko
Subjects: Reproduction, QH471-489
Abstract: Background and Aims: Maternal age is one of the success factors of in vitro fertilization (IVF). Specifically, advanced maternal age (AMA; defined as [Formula: see text]35 years) shows just a negligible impact upon fertilization rate and a mild impact upon embryo development to the blastocyst stage, but results in a dramatic impact upon blastocyst aneuploidy rate. This is also associated with a progressive decrease in ovarian stimulation so that the number of oocytes and embryos produced from an older maternal age becomes less and the implantation rate decreases. However, the high incidence of embryonic chromosomal abnormalities in young women does not exclusively prove that maternal age is related to the quality of the resulting embryos. This study aims to analyze the relationship between maternal age and the chromosomal status of the embryo. Method: This cross-sectional research was done on 30 embryos from 12 patients aged 28-40 years old who underwent an IVF program in three clinics. Embryos were cultured until blastocyst stage. Preimplantation genetic testing for aneuploidy (PGT-A) was done after blastocyst biopsy on day 5 or 6, and chromosomal analysis was done using the next generation testing (NGS) method. Then the relationship between maternal age with embryo chromosomal status was analysed. Results: There is no difference in subjects’ characteristics between the euploid and aneuploid embryo groups (p>0.05). There is no significant difference in maternal age of the euploid and aneuploid embryo groups. (With p=0.690). Conclusion: Maternal age has no relationship with embryo chromosomal status. There is no specific pattern in the relationship between age and chromosomal status, except in the age range of 36 to 40 years, it is found that increasing age increases the number of aneuploid embryos and decreases the number of euploid embryos.
Published: 2023
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15. General versus spinal anesthesia in percutaneous nephrolithotomy: A systematic review and meta-analysis [version 2; peer review: 2 approved, 1 not approved]

Author: Ponco Birowo, Nur Rasyid, Widi Atmoko, Prof. Sung Yong Cho, Indah Suci Widyahening, Rinaldo Indra Rachman, and Ghifari Nurullah
Subjects: PCNL, Spinal Anesthesia, General Anesthesia, Complication, Stone-free Rate, eng, Medicine, Science
Abstract: Background: Percutaneous nephrolithotomy (PCNL) is the preferred treatment for the removal of large kidney stones, sized >20 mm. However, there is still an ongoing debate concerning the best anesthesia for PCNL. This study aimed to compare the efficacy and safety between general and spinal anesthesia for PCNL. Methods: A systematic review and meta-analysis study. A systematic, electronic literature search was performed in several databases, including PubMed, Scopus, and Google Scholar until July 1st, 2022. The quality of the articles was examined using Crombie's Items (for non-randomized controlled trials (RCTs)) and Jadad Scale (for RCTs). The outcomes assessed were operation time, fluoroscopy time, length of stay, stone-free rate, overall complication rate, specific postoperative complications, cost, pain score, and postoperative analgesic requirement. The article selection was reported based on the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines. We assessed four RCTs and eight retrospective studies. Meta-analysis of selected studies was performed using the Review Manager 5.3. Results: General anesthesia resulted in fewer Clavien–Dindo grade II (OR: 0.68; 95% CI: 0.49 – 0.94; p=0.02), major complications (OR: 0.65; 95% CI: 0.45 – 0.94; p=0.02, and lower transfusion rates (OR: 0.70; 95% CI: 0.53 – 0.94; p=0.02). Whereas spinal anesthesia resulted in faster operation time (Mean Difference: -12.98; 95% CI: -20.56 – -5.41; p
Published: 2023
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16. General versus spinal anesthesia in percutaneous nephrolithotomy: A systematic review and meta-analysis [version 1; peer review: 1 approved with reservations, 1 not approved]

Author: Rinaldo Indra Rachman, Ponco Birowo, Ghifari Nurullah, Prof. Sung Yong Cho, Widi Atmoko, Indah Suci Widyahening, and Nur Rasyid
Subjects: Systematic Review, Articles, PCNL, Spinal Anesthesia, General Anesthesia, Complication, Stone-free Rate
Abstract: Background: Percutaneous nephrolithotomy (PCNL) is the preferred treatment for the removal of large kidney stones, sized >20 mm. However, there is still an ongoing debate concerning the best anesthesia for PCNL. This study aimed to compare the efficacy and safety between general and spinal anesthesia for PCNL. Methods: A systematic review and meta-analysis study. A systematic, electronic literature search was performed in several databases, including PubMed, Scopus, and Google Scholar until July 1 st, 2022. The quality of the articles was examined using Crombie's Items (for non-randomized controlled trials (RCTs)) and Jadad Scale (for RCTs). The outcomes assessed were operation time, fluoroscopy time, length of stay, stone-free rate, overall complication rate, specific postoperative complications, cost, pain score, and postoperative analgesic requirement . The article selection was reported based on the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines . We assessed four RCTs and eight retrospective studies. Meta-analysis of selected studies was performed using the Review Manager 5.3. Results: General anesthesia resulted in fewer Clavien–Dindo grade II (OR: 0.68; 95% CI: 0.49 – 0.94; p=0.02), major complications (OR: 0.65; 95% CI: 0.45 – 0.94; p=0.02, and lower transfusion rates (OR: 0.70; 95% CI: 0.53 – 0.94; p=0.02). Whereas spinal anesthesia resulted in faster operation time (Mean Difference: -12.98; 95% CI: -20.56 – -5.41; p PCNL performed using either general anesthesia or spinal anesthesia is equally safe and effective. Conclusions: Each method of anesthesia has its own advantages and disadvantages. The final choice between general and spinal anesthesia should be based on the patient's condition and surgical team preference.
Published: 2023
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17. Assessment of the obesogenic environment in primary schools: a multi-site case study in Jakarta

Author: Khoe, Levina Chandra, Widyahening, Indah Suci, Ali, Syougie, and Khusun, Helda
Published: 2022
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18. Assessment of the obesogenic environment in primary schools: a multi-site case study in Jakarta

Author: Levina Chandra Khoe, Indah Suci Widyahening, Syougie Ali, and Helda Khusun
Subjects: Obesity, School, Nutrition environment, Children, Nutrition. Foods and food supply, TX341-641, Food processing and manufacture, TP368-456, Medicine (General), R5-920
Abstract: Abstract Background Childhood overweight and obesity have increasingly been recognized as a significant global public health crisis, including in Asia. This study aimed to assess the obesogenic environment in primary schools in Jakarta, Indonesia. Methods A qualitative, multi-site, case study design was used to capture different elements of the school environment and policies related to obesity, with a focus on nutrition and physical activity. An adaptation of the Primary School Environmental Assessment tool was used. Six primary schools in Jakarta were purposively selected based on their location, socioeconomic status, and type (public or private). In addition to direct observation at each school, interviews were conducted with the principal, physical education teacher, canteen staff, street food vendors, and students. Results Among the six schools, two were private and four were public. The most popular foods consumed by students were unhealthy, such as deep-fried foods and sugar-sweetened beverages. Students had easy and constant access to unhealthy foods, whereas only limited variation of healthy foods were available in the school canteen. Some schools also allowed the student to have access to street food vendors. School policies related to healthy eating and physical activities had been implemented, mainly in the form of teaching these topics as part of the school curriculum. However, promotion of healthy eating and physical activities by the schools was still limited. Conclusions This study showed the usefulness of the Primary School Environmental Assessment tool in identifying obesogenic factors in urban area of Indonesia. Effective implementation of guidelines to foster good nutritional practices and healthy lifestyles at school should be prioritized to improve the health and nutritional status of the students.
Published: 2022
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19. Peningkatan Keterampilan Berbicara Teks Analytical Exposition dengan Teknik Pemodelan pada Siswa Kelas X2 SMAN 1 Kalitidu

Author: Italusanti, Nur, primary and Widyahening, Christiana Evy, additional
Published: 2024
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20. The Value of Warning Signs From the WHO 2009 Dengue Classification in Detecting Severe Dengue in Children

Author: Karyanti, Mulya Rahma, primary, Uiterwaal, Cuno S. P. M., additional, Hadinegoro, Sri Rezeki, additional, Widyahening, Indah Suci, additional, Saldi, Siti Rizny F., additional, Heesterbeek, J. A. P. Hans, additional, Hoes, Arno W., additional, and Bruijning-Verhagen, Patricia, additional
Published: 2024
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21. Retinal abnormalities in universal eye screening of healthy, full-term newborn infants in Jakarta. The incidence and its risk factors: a pilot study

Author: Rita S. Sitorus, Indra Maharddhika Pambudy, Rinawati Rohsiswatmo, Julie Dewi Barliana, Dian Estu Yulia, and Indah Suci Widyahening
Subjects: Universal eye screening, Hemorrhage, Delivery, Healthy newborn, Ophthalmology, RE1-994
Abstract: Abstract Aim To screen for ocular abnormalities in healthy full-term newborn infants using wide-field digital imaging and to analyze factors associated with the findings. Methods A total of 1208 full-term newborn infants at a tertiary eye hospital (Cipto Mangunkusumo National Referral Hospital) and a district hospital in Jakarta (Koja Hospital) were enrolled to the study. All eligible newborns underwent fundus examination within 48 h after birth using the RetCam shuttle (Natus Medical Incorporated, USA). Retinal findings were documented and analyzed according to obstetric and neonatal risk factors. Results Of the 1208 newborn infants enrolled, ocular abnormalities were found in 150 infants (12.4%). Retinal hemorrhage (RH) was the most common finding (88%) in which 2.67% involved the macula, followed by chorioretinitis (4.67%). Univariate analysis showed caesarean section (C-section) (OR 0.27, 95% CI 0.18–0.41, p
Published: 2021
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22. LUNG CANCER ASSOCIATED WITH CARBON BLACK EXPOSURE ON BRICK WORKERS

Author: Anna nasriawati, Muhammad Ilyas, and Indah S Widyahening
Subjects: carbon black, lung cancer, workers, Public aspects of medicine, RA1-1270
Abstract: ABSTRACT Carbon black aerosol has potential risks to human health. It has been acknowledged to cause cardiovascular and respiratory diseases in humans. International Agency for Research on Cancer (IARC) 2010 stated that carbon black classification is 2b, which is carcinogenic. This research explains a case of lung cancer due to carbon black exposure and reviews the literature of occupational cases to get the answers about the effects of carbon black exposure and the increasing risk of lung cancer for workers exposed to carbon black. The literature review was performed to answer the clinical question via electronic databases: PubMed and Google Scholar. The keywords used were ‘carbon black’ and ‘lung cancer’ and 'workers'. The inclusion criteria of this searching strategy were the workers which exposed to carbon black, meta-analysis, randomized controlled trial, systematic reviews, cohort. The exclusion criteria of this article were inaccessible articles, RCTs that have been used in the recent systematic reviews. The selected articles were then critically appraised using relevant criteria by the Oxford Center for Evidence-based Medicine. This study reviews the literature by Rota Matteo; The epidemiological evidence on the polyaromatic hydrocarbon (PAH) high exposed, perspective cohort study by Delli LD, and the control case study by Marie EPt. All the researches above showed that carbon black carcinogenic potential is the same as the IARC monograph statement that the epidemiological studies of carbon black provide possible carcinogenicity (Group of 2B). Keywords: carbon black, lung cancer, workers
Published: 2021
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23. Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million participants

Author: Zhou, Bin, Carrillo-Larco, Rodrigo M, Danaei, Goodarz, Riley, Leanne M, Paciorek, Christopher J, Stevens, Gretchen A, Gregg, Edward W, Bennett, James E, Solomon, Bethlehem, Singleton, Rosie K, Sophiea, Marisa K, Iurilli, Maria LC, Lhoste, Victor PF, Cowan, Melanie J, Savin, Stefan, Woodward, Mark, Balanova, Yulia, Cifkova, Renata, Damasceno, Albertino, Elliott, Paul, Farzadfar, Farshad, He, Jiang, Ikeda, Nayu, Kengne, Andre P, Khang, Young-Ho, Kim, Hyeon Chang, Laxmaiah, Avula, Lin, Hsien-Ho, Margozzini Maira, Paula, Miranda, J Jaime, Neuhauser, Hannelore, Sundström, Johan, Varghese, Cherian, Widyahening, Indah S, Zdrojewski, Tomasz, Abarca-Gómez, Leandra, Abdeen, Ziad A, Abdul Rahim, Hanan F, Abu-Rmeileh, Niveen M, Acosta-Cazares, Benjamin, Adams, Robert J, Aekplakorn, Wichai, Afsana, Kaosar, Afzal, Shoaib, Agdeppa, Imelda A, Aghazadeh-Attari, Javad, Aguilar-Salinas, Carlos A, Agyemang, Charles, Ahmad, Noor Ani, Ahmadi, Ali, Ahmadi, Naser, Ahmadi, Nastaran, Ahmadizar, Fariba, Ahmed, Soheir H, Ahrens, Wolfgang, Ajlouni, Kamel, Al-Raddadi, Rajaa, Alarouj, Monira, AlBuhairan, Fadia, AlDhukair, Shahla, Ali, Mohamed M, Alkandari, Abdullah, Alkerwi, Ala'a, Allin, Kristine, Aly, Eman, Amarapurkar, Deepak N, Amougou, Norbert, Amouyel, Philippe, Andersen, Lars Bo, Anderssen, Sigmund A, Anjana, Ranjit Mohan, Ansari-Moghaddam, Alireza, Ansong, Daniel, Aounallah-Skhiri, Hajer, Araújo, Joana, Ariansen, Inger, Aris, Tahir, Arku, Raphael E, Arlappa, Nimmathota, Aryal, Krishna K, Aspelund, Thor, Assah, Felix K, Assunção, Maria Cecília F, Auvinen, Juha, Avdićová, Mária, Azevedo, Ana, Azimi-Nezhad, Mohsen, Azizi, Fereidoun, Azmin, Mehrdad, Babu, Bontha V, Bahijri, Suhad, Balakrishna, Nagalla, Bamoshmoosh, Mohamed, Banach, Maciej, Banadinović, Maja, Bandosz, Piotr, Banegas, José R, Baran, Joanna, Barbagallo, Carlo M, Barceló, Alberto, Barkat, Amina, Barreto, Marta, Barros, Aluisio JD, Barros, Mauro Virgílio Gomes, Bartosiewicz, Anna, Basit, Abdul, Bastos, Joao Luiz D, Bata, 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Ben, Schramm, Sara, Schultsz, Constance, Schutte, Aletta E, Sebert, Sylvain, Sein, Aye Aye, Sen, Abhijit, Senbanjo, Idowu O, Sepanlou, Sadaf G, Servais, Jennifer, Shalnova, Svetlana A, Shamah-Levy, Teresa, Shamshirgaran, Morteza, Shanthirani, Coimbatore Subramaniam, Sharafkhah, Maryam, Sharma, Sanjib K, Shaw, Jonathan E, Shayanrad, Amaneh, Shayesteh, Ali Akbar, Shi, Zumin, Shibuya, Kenji, Shimizu-Furusawa, Hana, Shin, Dong Wook, Shirani, Majid, Shiri, Rahman, Shrestha, Namuna, Si-Ramlee, Khairil, Siani, Alfonso, Siantar, Rosalynn, Sibai, Abla M, Silva, Caroline Ramos de Moura, Silva, Diego Augusto Santos, Simon, Mary, Simons, Judith, Simons, Leon A, Sjöström, Michael, Slowikowska-Hilczer, Jolanta, Slusarczyk, Przemyslaw, Smeeth, Liam, So, Hung-Kwan, Soares, Fernanda Cunha, Sobngwi, Eugène, Söderberg, Stefan, Soemantri, Agustinus, Sofat, Reecha, Solfrizzi, Vincenzo, Somi, Mohammad Hossein, Sonestedt, Emily, Song, Yi, Sørensen, Thorkild IA, Sørgjerd, Elin P, Sorić, Maroje, Sossa Jérome, Charles, Soumaré, Aïcha, Sparboe-Nilsen, Bente, Sparrenberger, Karen, Staessen, Jan A, Starc, Gregor, Stavreski, Bill, Steene-Johannessen, Jostein, Stehle, Peter, Stein, Aryeh D, Stergiou, George S, Stessman, Jochanan, Stieber, Jutta, Stöckl, Doris, Stocks, Tanja, Stokwiszewski, Jakub, Stronks, Karien, Strufaldi, Maria Wany, Suka, Machi, Sun, Chien-An, Sung, Yn-Tz, Suriyawongpaisal, Paibul, Sy, Rody G, Syddall, Holly E, Sylva, René Charles, Szklo, Moyses, Tai, E Shyong, Tammesoo, Mari-Liis, Tamosiunas, Abdonas, Tan, Eng Joo, Tang, Xun, Tanser, Frank, Tao, Yong, Tarawneh, Mohammed Rasoul, Tarqui-Mamani, Carolina B, Taylor, Anne, Taylor, Julie, Tebar, William R, Tell, Grethe S, Tello, Tania, Tham, Yih Chung, Thankappan, KR, Theobald, Holger, Theodoridis, Xenophon, Thijs, Lutgarde, Thinggaard, Mikael, Thomas, Nihal, Thorand, Barbara, Thuesen, Betina H, Timmermans, Erik J, Tjandrarini, Dwi H, Tjonneland, Anne, Toft, Ulla, Tolonen, Hanna K, Tolstrup, Janne S, Topbas, Murat, Topór-Madry, Roman, Tormo, María José, Tornaritis, Michael J, Torrent, Maties, Torres-Collado, Laura, Touloumi, Giota, Traissac, Pierre, Triantafyllou, Areti, Trichopoulos, Dimitrios, Trichopoulou, Antonia, Trinh, Oanh TH, Trivedi, Atul, Tshepo, Lechaba, Tsugane, Shoichiro, Tuliakova, Azaliia M, Tulloch-Reid, Marshall K, Tullu, Fikru, Tuomainen, Tomi-Pekka, Tuomilehto, Jaakko, Turley, Maria L, Twig, Gilad, Tynelius, Per, Tzourio, Christophe, Ueda, Peter, Ugel, Eunice, Ulmer, Hanno, Uusitalo, Hannu MT, Valdivia, Gonzalo, Valvi, Damaskini, van Dam, Rob M, van den Born, Bert-Jan, Van der Heyden, Johan, van der Schouw, Yvonne T, Van Herck, Koen, Van Minh, Hoang, Van Schoor, Natasja M, van Valkengoed, Irene GM, van Zutphen, Elisabeth M, Vanderschueren, Dirk, Vanuzzo, Diego, Varbo, Anette, Vasan, Senthil K, Vega, Tomas, Veidebaum, Toomas, Velasquez-Melendez, Gustavo, Veronesi, Giovanni, Verschuren, WM Monique, Verstraeten, Roosmarijn, Victora, Cesar G, Viet, Lucie, Villalpando, Salvador, Vineis, Paolo, Vioque, Jesus, Virtanen, Jyrki K, Visvikis-Siest, Sophie, Viswanathan, Bharathi, Vlasoff, Tiina, Vollenweider, Peter, Voutilainen, Ari, Wade, Alisha N, Walton, Janette, Wambiya, Elvis OA, Wan Bebakar, Wan Mohamad, Wan Mohamud, Wan Nazaimoon, Wanderley Júnior, Rildo de Souza, Wang, Ming-Dong, Wang, Ningli, Wang, Qian, Wang, Xiangjun, Wang, Ya Xing, Wang, Ying-Wei, Wannamethee, S Goya, Wareham, Nicholas, Wei, Wenbin, Weres, Aneta, Werner, Bo, Whincup, Peter H, Widhalm, Kurt, Wiecek, Andrzej, Wilks, Rainford J, Willeit, Johann, Willeit, Peter, Williams, Emmanuel A, Wilsgaard, Tom, Wojtyniak, Bogdan, Wong-McClure, Roy A, Wong, Andrew, Wong, Tien Yin, Woo, Jean, Wu, Frederick C, Wu, Shouling, Wyszynska, Justyna, Xu, Haiquan, Xu, Liang, Yaacob, Nor Azwany, Yan, Weili, Yang, Ling, Yang, Xiaoguang, Yang, Yang, Yasuharu, Tabara, Ye, Xingwang, Yiallouros, Panayiotis K, Yoosefi, Moein, Yoshihara, Akihiro, You, San-Lin, Younger-Coleman, Novie O, Yusoff, Ahmad Faudzi, Zainuddin, Ahmad A, Zakavi, Seyed Rasoul, Zamani, Farhad, Zambon, Sabina, Zampelas, Antonis, Zapata, Maria Elisa, Zaw, Ko Ko, Zejglicova, Kristyna, Zeljkovic Vrkic, Tajana, Zeng, Yi, Zhang, Luxia, Zhang, Zhen-Yu, Zhao, Dong, Zhao, Ming-Hui, Zhen, Shiqi, Zheng, Yingfeng, Zholdin, Bekbolat, Zhu, Dan, Zins, Marie, Zitt, Emanuel, Zocalo, Yanina, Zoghlami, Nada, Zuñiga Cisneros, Julio, and Ezzati, Majid
Published: 2021
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24. The Value of Warning Signs From the WHO 2009 Dengue Classification in Detecting Severe Dengue in Children

Author: Karyanti, Mulya Rahma, Uiterwaal, Cuno S.P.M., Hadinegoro, Sri Rezeki, Widyahening, Indah Suci, Saldi, Siti Rizny F., Heesterbeek, J. A.P.Hans, Hoes, Arno W., Bruijning-Verhagen, Patricia, Karyanti, Mulya Rahma, Uiterwaal, Cuno S.P.M., Hadinegoro, Sri Rezeki, Widyahening, Indah Suci, Saldi, Siti Rizny F., Heesterbeek, J. A.P.Hans, Hoes, Arno W., and Bruijning-Verhagen, Patricia
Abstract: BACKGROUND: World Health Organization proposed 7 warning signs to identify the risk of severe dengue in 2009. This study aimed to evaluate the value of these warning signs in detecting severe dengue in children. MATERIAL AND METHODS: A cross-sectional study was conducted utilizing data of children with clinical dengue infection obtained from medical records between January 2009 and December 2018 in Jakarta. Children with confirmed dengue were analyzed and stratified into 3 age groups: infants less than 1 year old, children 1-14 years and adolescents 15-18 years of age. Positive predictive value, negative predictive value (NPV), sensitivity and specificity of each warning sign present or absent on admission in detecting severe dengue were computed. RESULTS: Six hundred ninety-nine children with clinical dengue infection were enrolled, among whom 614 (87.8%) had confirmed dengue infection, either by antigen or antibody serological tests. Severe dengue occurred in 211/614 (34.4%) cases. In infants, important warning signs on admission to detect or exclude severe dengue were liver enlargement (NPV 80.8%) and clinical fluid accumulation (NPV 75%). In children and adolescents, warning sign with highest NPV (in children 76.6% and in adolescents 91.9%) was increase in hematocrit concurrent with a rapid decrease in platelet count. Other warning signs with high NPV values in children were abdominal pain (72%), vomiting (70%), clinical fluid accumulation (69.3%), and in adolescents' abdominal pain (80.7%), vomiting (75.7%), clinical fluid accumulation (82.7%). NPVs increase with more than 1 warning sign in all age groups. CONCLUSION: In infants, liver enlargement or clinical fluid accumulation are important warning signs for severe dengue, when both are absent, severe dengue is unlikely. In older children and adolescents, an increase in hematocrit with the concurrent rapid decrease in platelet count is most discriminative; followed by the absence of abdominal pain, vomiting
Published: 2024

25. The Value of Warning Signs From the WHO 2009 Dengue Classification in Detecting Severe Dengue in Children

Author: Infection & Immunity, Global Health, Cardiovasculaire Epi Team 1, Directie Raad van Bestuur, Circulatory Health, Epi Infectieziekten Team 1, Child Health, JC onderzoeksprogramma Infectieziekten, Karyanti, Mulya Rahma, Uiterwaal, Cuno S P M, Hadinegoro, Sri Rezeki, Widyahening, Indah Suci, Saldi, Siti Rizny F, Heesterbeek, J A P Hans, Hoes, Arno W, Bruijning-Verhagen, Patricia, Infection & Immunity, Global Health, Cardiovasculaire Epi Team 1, Directie Raad van Bestuur, Circulatory Health, Epi Infectieziekten Team 1, Child Health, JC onderzoeksprogramma Infectieziekten, Karyanti, Mulya Rahma, Uiterwaal, Cuno S P M, Hadinegoro, Sri Rezeki, Widyahening, Indah Suci, Saldi, Siti Rizny F, Heesterbeek, J A P Hans, Hoes, Arno W, and Bruijning-Verhagen, Patricia
Published: 2024

26. Willingness to volunteer and readiness to practice of undergraduate medical students during the COVID-19 pandemic: a cross-sectional survey in Indonesia

Author: Gilbert Lazarus, Ardi Findyartini, Azis Muhammad Putera, Nico Gamalliel, David Nugraha, Imam Adli, Jason Phowira, Lyanna Azzahra, Bagas Ariffandi, and Indah Suci Widyahening
Subjects: COVID-19, Indonesia, Medical students, Readiness to practice, Willingness to volunteer, Special aspects of education, LC8-6691, Medicine
Abstract: Abstract Background The question to involve or restrict medical students’ involvement in the coronavirus disease 2019 (COVID-19) pandemic response remains contentious. As their state of preparation and perceptions in volunteering during this pandemic have yet to be investigated, this study aims to evaluate Indonesian medical students’ willingness to volunteer and readiness to practice during the COVID-19 pandemic. Methods A web-based survey was conducted among undergraduate medical students throughout Indonesia. Socio-demographic and social interaction information, in addition to willingness to volunteer and readiness to practice, were obtained using a self-reported questionnaire. The significance level was set at 5%. Results Among 4870 participants, 2374 (48.7%) expressed their willingness to volunteer, while only 906 (18.6%) had adequate readiness to practice. Male students, students with prior volunteering experience in health or non-health sectors, and students from public universities or living in Central Indonesia (vs Java) had higher scores of willingness and readiness to volunteer. Students from Sumatra also had better preparedness (odds ratio [OR] 1.56, 95% confidence interval [CI] 1.15–2.12, p = 0.004), while the opposite occurred for students from Eastern Indonesia (OR 0.63, 95% CI: 0.44–0.89, p = 0.002)–when compared to students from Java. In addition, compared to students with high family income, students from lower-middle income families were less willing to volunteer (OR 0.76, 95% CI: 0.59–0.98, p = 0.034), though those with low family income had better readiness (OR 1.51, 95% CI: 1.10–2.08, p = 0.011). Shortage of medical personnel, sense of duty, and solicitation by stakeholders were the main reasons increasing the students’ willingness to volunteer; whereas contrarily fear for own’s health, absence of a cure, and fear of harming patients were the primary factors diminishing their willingness to volunteer. Conclusion Our findings indicated that many Indonesian medical students are willing to volunteer, yet only few of them were ready to practice, indicating that further preparations are required to maximize their potentials and minimize their exposure to hazards. We suggest that their potentials as a firm support system during the pandemic should not be overlooked, and that the integration of relevant courses to the medical curricula are imperative to prepare for future public health emergencies.
Published: 2021
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27. Editorial: Achieving Effective Management and Treatment of Diabetes Mellitus in Future Primary Care

Author: Indah Suci Widyahening, Kamlesh Khunti, Rimke C. Vos, and Boon-How Chew
Subjects: diabetes, primary care, treatment, quality of care, comprehensive management, Diseases of the endocrine glands. Clinical endocrinology, RC648-665
Published: 2022
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28. Editorial: Achieving Efficient Diabetes Care Through Understanding the Risk Factors, Markers, and Patient Experiences

Author: Boon-How Chew, Rimke C. Vos, Indah Suci Widyahening, and Kamlesh Khunti
Subjects: diabetes care, efficient, risk factors, biomarkers, patient’s experience, Diseases of the endocrine glands. Clinical endocrinology, RC648-665
Published: 2022
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29. The benefits of varicocele repair for achieving pregnancy in male infertility: A systematic review and meta-analysis

Author: Birowo, Ponco, Tendi, William, Widyahening, Indah Suci, Atmoko, Widi, and Rasyid, Nur
Published: 2020
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30. Peran Ibu Dalam Membudayakan Minat Baca Melalui Kegiatan Mendongeng Bagi Anak

Author: Tri Widyahening, Christiana Evy, primary and Al Hakim, Luqman, primary
Published: 2024
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31. Mental Health Awareness and Promotion during the First 1000 Days of Life: An Expert Consensus

Author: Wardoyo, Hasto, primary, Moeloek, Nila Djuwita, additional, Basrowi, Ray Wagiu, additional, Ekowati, Maria, additional, Samah, Kristin, additional, Mustopo, Widura Imam, additional, Nurdjasmi, Emi, additional, Widyahening, Indah Suci, additional, Medise, Bernie Endyarni, additional, Darus, Febriansyah, additional, Sundjaya, Tonny, additional, and Pelangi, Bunga, additional
Published: 2023
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32. Type 2 Diabetes in Non-Sedentary Workers with Long Working Hours “An Evidence-Based Case Report”

Author: Sofyan, Marwan, primary, Widyahening, Indah Suci, additional, and Soemarko, Dewi Sumaryani, additional
Published: 2023
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33. Hubungan Persentase Lemak Tubuh dengan Nilai V̇O2 Maks Penerbang TNI AU

Author: Widianto, Eri, primary, Wibawanti, Retno, additional, Mulijadi, Herman, additional, Widyahening, Indah Suci, additional, Isbaniah, Fathiyah, additional, Sinabutar, Klara, additional, and Kekalih, Aria, additional
Published: 2023
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34. #279 : The Relationship Between Maternal Age and the Chromosomal Status of the Embryo

Author: Kurniawan, Riyan Hari, primary, Muharam, Raden, additional, Widyahening, Indah Suci, additional, Iffanolida, Pritta Ameilia, additional, and Wiweko, Budi, additional
Published: 2023
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35. #278 : Relationship Between Level Expression of miRNA-191 and miRNA-548c-3p in Embryo Culture Medium and Embryo Chromosomal Status

Author: Kurniawan, Riyan Hari, primary, Muharam, Raden, additional, Widyahening, Indah Suci, additional, Iffanolida, Pritta Ameilia, additional, and Wiweko, Budi, additional
Published: 2023
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36. Noncommunicable diseases risk factors and the risk of COVID-19 among university employees in Indonesia

Author: Indah Suci Widyahening, Dhanasari Vidiawati, Trevino A. Pakasi, Pradana Soewondo, and Abdillah Ahsan
Subjects: Medicine, Science
Abstract: Introduction Noncommunicable diseases (NCDs) are still a major public health problem in Indonesia. Studies have shown that risk factors of NCDs are associated with coronavirus disease 2019 (COVID-19) severity and mortality. However, it is unclear whether NCD risk factors are also risks for new COVID-19 cases. This study aimed to obtain an NCD risk profile among university employees and its associations with contracting COVID-19. Methods A cross-sectional study was conducted in October 2021. Participants were administrative employees of Universitas Indonesia (UI), Depok City, West Java. Assessment of NCD risk factors was based on the World Health Organization STEPwise approach to NCD risk factor surveillance (WHO STEPS). Demographic, working, and medical-history data were obtained electronically by using a Google Form. Physical and laboratory examinations were done in the Integrated Post for NCDs. Risks were expressed as adjusted odds ratio (ORadj) and 95% confidence interval (CI) in multivariate analyses. Results A total of 613 employees were enrolled. Men were predominant (54.8%), and about 36% of them work in shift as security personnel. About 66.7% were overweight or obese and 77.8% had hypertension. There were 138 (22.8%) employees who had COVID-19. Nearly all (95.6%) had been fully vaccinated against COVID-19. At-risk waist circumference (ORadj 1.72, 95% CI 1.15–2.56, p = 0.008) and total cholesterol level of 200–239 mg/dL (ORadj 2.30, 95% CI 1.19–4.44, p = 0.013) were independent risk factors, but shift work (ORadj 0.52, 95% CI 0.34–0.80, p = 0.003) was protective against COVID-19. Conclusion The prevalence of NCD risk factors among university administrative employees was high, increasing the risk of contracting COVID-19. A behavioral intervention program to manage NCD risk factors at the university level is urgently needed according to the Health Promoting University framework.
Published: 2022

37. Knowledge, attitude, and practice related to the COVID-19 pandemic among undergraduate medical students in Indonesia: A nationwide cross-sectional study

Author: Imam Adli, Indah Suci Widyahening, Gilbert Lazarus, Jason Phowira, Lyanna Azzahra Baihaqi, Bagas Ariffandi, Azis Muhammad Putera, David Nugraha, Nico Gamalliel, and Ardi Findyartini
Subjects: Medicine, Science
Abstract: Introduction The potential role of medical students in raising awareness during public health emergencies has been acknowledged. To further explore their potentials as public educators and role models for the communities during the coronavirus disease 2019 (COVID-19) pandemic, this study aims to assess the knowledge, attitude, and practice of these students toward COVID-19. Methods An online cross-sectional survey was conducted among undergraduate medical students in Indonesia. Socio-demographics characteristics, social interaction history, information-seeking behavior, as well as knowledge, attitude, and practice toward COVID-19 were collected through a self-reported questionnaire. A p-value of Results Out of 4870 respondents, 64.9% had positive attitude and 51.5% had positive practice toward COVID-19, while only 29.8% had adequate knowledge. Knowledge was slightly positively correlated with attitude and practice (ρ = 0.074 and ρ = 0.054, respectively; both pConclusion Many undergraduate medical students in Indonesia had positive attitude and practice against COVID-19, yet only a few had adequate knowledge. This warrants further interventions to keep them updated with COVID-19 evidence to maximize their potentials in raising public awareness on COVID-19.
Published: 2022

38. Willingness to volunteer and readiness to practice of undergraduate medical students during the COVID-19 pandemic: a cross-sectional survey in Indonesia

Author: Lazarus, Gilbert, Findyartini, Ardi, Putera, Azis Muhammad, Gamalliel, Nico, Nugraha, David, Adli, Imam, Phowira, Jason, Azzahra, Lyanna, Ariffandi, Bagas, and Widyahening, Indah Suci
Published: 2021
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39. Retinal abnormalities in universal eye screening of healthy, full-term newborn infants in Jakarta. The incidence and its risk factors: a pilot study

Author: Sitorus, Rita S., Pambudy, Indra Maharddhika, Rohsiswatmo, Rinawati, Barliana, Julie Dewi, Yulia, Dian Estu, and Widyahening, Indah Suci
Published: 2021
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40. Extracoporeal shockwave treatment decreases pain, functional limitations and medial collateral ligament thickness in subjects aged 50-70 years with knee osteoarthritis

Author: Andwi Setiawan Kokok, Tirza Z Tamin, Nyoman Murdana, and Indah Suci Widyahening
Subjects: Knee osteoarthritis, quasi-experimental, extracorporeal shockwave therapy, medial collateral ligament, Medicine
Abstract: Background Pain from knee and hip osteoarthritis (OA) can have a significant impact on the physical function and quality of life of affected individuals worldwide. The objective of this study was to evaluate the effect of extracorporeal shockwave therapy (ESWT) on pain, flexibility, function, and medial collateral ligament (MCL) thickness in knee osteoarthritis (KOA). Methods A study of quasi experimental design was performed involving 15 subjects aged 50 – 70 years with Kellgren-Lawrence grade 2-3 KOA. All subjects were evaluated regarding baseline -pain using visual analogue scale (VAS), range of motion (ROM), functional outcome using Western Ontario and McMaster Universities Arthritis Index (WOMAC), and MCL size. Extracorporeal shock wave therapy was given 3 times, at baseline, and 4 and 8 weeks after intervention. All subjects were given 4000 shocks at intensities of 1.5 – 4 Bar (raised gradually) per session. The shocks were given in the supine position, knee flexed 90o, without topical anesthetic. Statistical analyses were conducted using a dependent t-test. Results After 8 weeks of intervention, ESWT significantly improved pain score (p0.05). Conclusion The use of ESWT for treatment of knee OA had a beneficial effect on pain relief, function outcome and MCL thickness. However, there remains a lack of clarity regarding the frequency and dosage levels of ESWT required to achieve maximum improvement.
Published: 2021
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41. Prospect of Mesenchymal Stem Cells in Enhancing Nerve Regeneration in Brachial Plexus Injury in Animals: A Systematic Review.

Author: Widodo, Wahyu, Widyahening, Indah Suci, Pratama, Irfan Kurnia, and Kuncoro, Mohamad Walid
Published: 2024
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42. General versus spinal anesthesia in percutaneous nephrolithotomy: A systematic review and meta-analysis

Author: Indra Rachman, Rinaldo, primary, Birowo, Ponco, additional, Nurullah, Ghifari, additional, Cho, Prof. Sung Yong, additional, Atmoko, Widi, additional, Widyahening, Indah Suci, additional, and Rasyid, Nur, additional
Published: 2023
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43. Myopia Progression during COVID-19 Home Quarantine in Indonesia: A Retrospective Multicenter Cohort Study

Author: Sitorus, Rita S, primary, Caesarya, Sesy, additional, Karfiati, Feti, additional, Manurung, Florence M, additional, Ekowati, Liana, additional, Sumual, Vera, additional, Loebis, Rozalina, additional, Darusman, Kianti Raisa, additional, Surasmiati, Ni made Ayu, additional, Sayuti, Kemala, additional, Aldy, Fithria, additional, Wulandari, Lely Retno, additional, Rahmah, Marlyanti Nur, additional, Estu, Dian, additional, Barliana, Julie Dewi, additional, Prabaniswara, Marcelius Patria, additional, Sutandi, Nathania, additional, and Widyahening, Indah Suci, additional
Published: 2023
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44. Knowledge, attitudes, and practices regarding male infertility: A cross-sectional study among infertile couples visiting fertility clinics in Indonesia’s urban areas

Author: Mushlih, Yusuf, primary, Adli, Imam, additional, Araysi, Leo Alfath, additional, Suryoadji, Kemal Akbar, additional, Indra Rachman, Rinaldo, additional, Nurullah, Ghifari, additional, Indy Christanto, Roberto Bagaskara, additional, Savira, Missy, additional, Shah, Rupin, additional, Agarwal, Ashok, additional, Widyahening, Indah Suci, additional, Pratama, Gita, additional, Duarsa, Gede Wirya Kusuma, additional, Adriansjah, Ricky, additional, Parikesit, Dyandra, additional, Atmoko, Widi, additional, Rasyid, Nur, additional, and Birowo, Ponco, additional
Published: 2023
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45. Levothyroxine use and thyroid gland volumes in children with autoimmune thyroiditis: a systematic review and meta-analysis

Author: Annang Giri Moelyo, Indah Suci Widyahening, and Bambang Tridjaja
Subjects: autoimmune thyroiditis, euthyroid, levothyroxine, thyroid volume, Medicine, Pediatrics, RJ1-570
Abstract: Background Autoimmune thyroiditis may manifest as overt hypothyroidism, subclinical hypothyroidism, euthyroidism, or hyperthyroidism in children. Although there is no consensus on treating euthyroidism and autoimmune thyroiditis in children, some studies have demonstrated the efficacy of levothyroxine in reducing thyroid volume, improving thyroid function, and stabilizing the immunological process. Objective To determine the effect of levothyroxine on thyroid gland volume changes, thyroid function, and thyroid antibodies in euthyroid children with autoimmune thyroiditis. Methods We performed a literature search of electronic databases (the Cochrane Library, MEDLINE, EBSCO, ProQuest, clinicaltrials.gov, and other sources, as well as a non-electronic search (searching journals and conference proceedings by hand) to identify studies of euthyroid children with autoimmune thyroiditis published by August 2018. Only English-language articles were included in the search (electronic and non-electronic). Randomized controlled trials that compared levothyroxine with a control (placebo or no treatment) in euthyroid children with autoimmune thyroiditis were selected. The outcome measures were thyroid volume changes, thyroid function, and thyroid antibody levels in euthyroid children with autoimmune thyroiditis. Two authors independently extracted the data, assessed the risk of bias, and analyzed the pooled data from the included studies using a random effects model. The same authors performed a sensitivity analysis. Results We identified 57 studies. Of these, three studies, involving 97 subjects (51 subjects in an intervention group and 46 subjects in the control group) were selected for inclusion in a systematic review/meta-analysis. The meta-analysis revealed a significant difference in mean thyroid volume changes between the two groups (-1.10 SDs; 95%CI -1.56 to -0.64; P
Published: 2019
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46. Supine versus prone position in percutaneous nephrolithotomy: a systematic review and meta-analysis [version 3; peer review: 2 approved]

Author: Ponco Birowo, William Tendi, Indah S. Widyahening, Nur Rasyid, and Widi Atmoko
Subjects: Systematic Review, Articles, Complication rate, Percutaneous nephrolithotomy, Prone, Stone free rate, Supine
Abstract: Background: The decision for using supine or prone position in percutaneous nephrolithotomy (PCNL) is still debatable. The aim of this study is to compare the efficacy and safety profile of the supine and prone position when performing PCNL. Methods: A systematic electronic search was performed using the database from MEDLINE, Cochrane library and Google Scholar from January 2009 to November 2019. The outcomes assessed were stone free rate, major complication rate, length of hospital stay and mean operation time. Results: A total of 11 articles were included in qualitative and quantitative analysis. The efficacy of PCNL in supine position as determined by stone free rate is significantly lower than in prone position (OR: 0.74; 95% CI: 0.66 – 0.83; p Conclusion: Prone position leads to a higher stone free rate, but also a higher rate of major complication. Thus, the decision of using which position during PCNL should be based on the surgeon’s experience and clinical aspects of the patients.
Published: 2020
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47. Supine versus prone position in percutaneous nephrolithotomy: a systematic review and meta-analysis [version 2; peer review: 1 approved, 1 approved with reservations]

Author: Ponco Birowo, William Tendi, Indah S. Widyahening, Nur Rasyid, and Widi Atmoko
Subjects: Systematic Review, Articles, Complication rate, Percutaneous nephrolithotomy, Prone, Stone free rate, Supine
Abstract: Background: The decision for using supine or prone position in percutaneous nephrolithotomy (PCNL) is still debatable. The aim of this study is to compare the efficacy and safety profile of the supine and prone position when performing PCNL. Methods: A systematic electronic search was performed using the database from MEDLINE, Cochrane library and Google Scholar from January 2009 to November 2019. The outcomes assessed were stone free rate, major complication rate, length of hospital stay and mean operation time. Results: A total of 11 articles were included in qualitative and quantitative analysis. The efficacy of PCNL in supine position as determined by stone free rate is significantly lower than in prone position (OR: 0.74; 95% CI: 0.66 – 0.83; p Conclusion: Prone position leads to a higher stone free rate, but also a higher rate of major complication. Thus, the decision of using which position during PCNL should be based on the surgeon’s experience and clinical aspects of the patients.
Published: 2020
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48. Supine versus prone position in percutaneous nephrolithotomy: a systematic review and meta-analysis [version 1; peer review: 2 approved, 1 approved with reservations]

Author: Ponco Birowo, William Tendi, Indah S. Widyahening, Nur Rasyid, and Widi Atmoko
Subjects: Systematic Review, Articles, Complication rate, Percutaneous nephrolithotomy, Prone, Stone free rate, Supine
Abstract: Background: The decision for using supine or prone position in percutaneous nephrolithotomy (PCNL) is still debatable. The aim of this study is to compare the efficacy and safety profile of the supine and prone position when performing PCNL. Methods: A systematic electronic search was performed using the database from MEDLINE, Cochrane library and Google Scholar from January 2009 to November 2019. The outcomes assessed were stone free rate, major complication rate, length of hospital stay and mean operation time. Results: A total of 11 articles were included in qualitative and quantitative analysis. The efficacy of PCNL in supine position as determined by stone free rate is significantly lower than in prone position (OR: 0.74; 95% CI: 0.66 – 0.83; p Conclusion: Prone position leads to a higher stone free rate, but also a higher rate of major complication. Thus, the decision of using which position during PCNL should be based on the surgeon’s experience and clinical aspects of the patients.
Published: 2020
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49. Moral Values in a Movie Entitled Frozen by Jennifer Lee

Author: null Ch. Evy Tri Widyahening, null Ericha Nataliana Nugraheni, and null MH Sri Rahayu
Abstract: The objective of this research was to analyze the character education values which were described by the characters in “Frozen” movie. This research is classified as a qualitative research type using a descriptive approach. The data from this study comes from “Frozen” movie and dialogue. Then, in collecting data the researcher used documentation by watching the movie and reading the script. In analyzing data, the researcher used interactive data analysis by Miles and Huberman. To find the research's validity, triangulation data and triangulation theory were used to check validation for the data. The result of this research has demonstrated that there are character education values that could be found in the movie entitled Frozen, such as self-control, hardworking, friendly & cheerful, social care, and responsibility that depicted by the characters of Elsa, Anna, Kristoff, and Olaf
Published: 2023
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50. Eksplorasi Nilai Humanisme dalam Autobiography of Frederick Douglass: An American Slave

Author: null Christiana Evy Tri Widyahening and null Ulupi Sitoresmi
Subjects: General Medicine
Abstract: Autobiografi merupakan salah satu jenis karya sastra yang masuk pada ranah prosa yang juga menjadi salah satu media untuk merekam peristiwa seseorang pada masanya yang ditulis sendiri oleh orang tersebut. Penelitian ini bertujuan untuk mendeskripsikan dan menjelaskan nilai-nilai humanisme dalam otobiografi Frederick Douglass: An American Slave karya Frederick Douglass. Bentuk penelitian ini adalah deskriptif kualitatif dengan jenis penelitian kepustakaan. Data dalam penelitian dianalisis secara cermat untuk mendapatkan hasil yang sesuai dengan tujuan penelitian. Prosedur pengumpulan data melalui teknik membaca dan mencatat. Masalah yang berkaitan dengan analisis nilai humanisme diperoleh dengan membaca otobiografi ini secara keseluruhan, cermat, menafsirkan unsur-unsur humanisme, dan mencatat kutipan langsung atau disebut juga verbatim. Hasil penelitian menunjukkan bahwa terdapat beberapa nilai humanisme yang diperoleh seperti 1) fitrah (manusia memiliki kehendak bebas untuk menentukan langkahnya sendiri), 2) hak asasi manusia, 3) keadilan (tidak memihak siapapun), dan 4) potensi (kemampuan yang dimiliki oleh manusia oleh setiap manusia di dunia). Nilai humanism yang terdapat pada potensi dalam Narrative of the Life of Frederick Douglass: An American Slave adalah menggambarkan bagaimana seorang budak kulit hitam yang dianggap hina dan tidak berharga justru dengan kegigihannya yang luar biasa mampu untuk bangkit, terlepas dari belenggu perbudakan dan memperlihatkan kemampuannya sebagai seorang orator ulung yang berjuang demi kebebasan kaumnya.
Published: 2023
Full Text: View/download PDF

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