160 results on '"Widjaja, Anissa A"'
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2. Inhibition of IL-11 signalling extends mammalian healthspan and lifespan
3. Vitamin B12 and folate decrease inflammation and fibrosis in NASH by preventing syntaxin 17 homocysteinylation
4. IL11 stimulates ERK/P90RSK to inhibit LKB1/AMPK and activate mTOR initiating a mesenchymal program in stromal, epithelial, and cancer cells
5. A high-resolution map of human RNA translation
6. Interleukin 11 therapy causes acute left ventricular dysfunction.
7. Spermidine-mediated hypusination of translation factor EIF5A improves mitochondrial fatty acid oxidation and prevents non-alcoholic steatohepatitis progression
8. Targeting endogenous kidney regeneration using anti-IL11 therapy in acute and chronic models of kidney disease
9. Abstract 13138: Dissection of Cardiomyocyte versus Fibroblast Effects of Interleukin-11 in Heart Failure
10. BS03 Interleukin-11: pro-inflammatory, profibrotic and cardiotoxic – a new therapeutic target in heart failure
11. Hepatocyte-specific IL11 cis-signaling drives lipotoxicity and underlies the transition from NAFLD to NASH
12. Similarities and differences between IL11 and IL11RA1 knockout mice for lung fibro-inflammation, fertility and craniosynostosis
13. Inhibiting Interleukin 11 Signaling Reduces Hepatocyte Death and Liver Fibrosis, Inflammation, and Steatosis in Mouse Models of Nonalcoholic Steatohepatitis
14. The Translational Landscape of the Human Heart
15. Nonspecific Inhibition of IL6 Family Cytokine Signalling by Soluble gp130
16. The Pathobiology of IL-11 in Kidney Disease
17. Interleukin 11 therapy causes acute heart failure and its use in patients should be reconsidered
18. Interleukin-11 is important for vascular smooth muscle phenotypic switching and aortic inflammation, fibrosis and remodeling in mouse models
19. Cardiomyocyte-Restricted Expression of IL11 Causes Cardiac Fibrosis, Inflammation, and Dysfunction
20. Widespread Translational Control of Fibrosis in the Human Heart by RNA-Binding Proteins
21. IL-11 is a crucial determinant of cardiovascular fibrosis
22. IL11 Stimulates IL33 Expression and Proinflammatory Fibroblast Activation across Tissues
23. IL11 stimulates IL33 expression and proinflammatory fibroblast activation
24. Hepatocyte Specific gp130 Signalling Underlies APAP Induced Liver Injury
25. Thyroid Hormone Decreases Hepatic Steatosis, Inflammation, and Fibrosis in a Dietary Mouse Model of Nonalcoholic Steatohepatitis
26. A Neutralizing IL-11 Antibody Improves Renal Function and Increases Lifespan in a Mouse Model of Alport Syndrome
27. Interleukin-11 drives human and mouse alcohol-related liver disease
28. IL11 Activates Pancreatic Stellate Cells and Causes Pancreatic Inflammation, Fibrosis and Atrophy in a Mouse Model of Pancreatitis
29. Inhibition of IL11 Signaling Reduces Aortic Pathology in Murine Marfan Syndrome
30. IL11 stimulates ERK/P90RSK to inhibit LKB1/AMPK and activate mTOR in hepatocytes, the stroma and cancer cells
31. Interleukin-11 drives human and mouse alcohol-related liver disease.
32. Molecular Dissection of Pro-Fibrotic IL11 Signaling in Cardiac and Pulmonary Fibroblasts
33. Critical Conditions for Studying Interleukin‐11 Signaling In Vitro and Avoiding Experimental Artefacts
34. The pro-regenerative effects of hyperIL6 in drug-induced liver injury are unexpectedly due to competitive inhibition of IL11 signaling
35. Interleukin-11 plays a key role in human and mouse alcohol-related liver disease
36. Author response: The pro-regenerative effects of hyperIL6 in drug-induced liver injury are unexpectedly due to competitive inhibition of IL11 signaling
37. Molecular dissection of pro-fibrotic signaling identifies the mechanism underlying IL11-driven fibrosis gene translation, reveals non-specific effects of STAT3 and suggests a new mechanism of action for nintedanib
38. Redefining IL11 as a regeneration-limiting hepatotoxin and therapeutic target in acetaminophen-induced liver injury
39. IL11 is elevated in systemic sclerosis and IL11-dependent ERK signaling underlies TGFβ-mediated activation of dermal fibroblasts
40. IL11 is elevated in systemic sclerosis and IL11-dependent ERK signalling underlies TGFβ-mediated activation of dermal fibroblasts
41. Antibody‐mediated neutralization of IL11 signalling reduces ERK activation and cardiac fibrosis in a mouse model of severe pressure overload
42. Similarities and differences between IL11 and IL11RA1 knockout mice for lung fibro-inflammation, fertility and craniosynostosis
43. Fibroblast‐specific IL11 signaling drives chronic inflammation in murine fibrotic lung disease
44. Different roles of interleukin 6 and interleukin 11 in the liver: implications for therapy
45. Autocrine IL11 cis-signaling in hepatocytes is an initiating nexus between lipotoxicity and non-alcoholic steatohepatitis
46. Crystallographic structure of the tetratricopeptide repeat domain of Plasmodium falciparum FKBP35 and its molecular interaction with Hsp90 C-terminal pentapeptide
47. Transgenic interleukin 11 expression causes cross-tissue fibro-inflammation and an inflammatory bowel phenotype in mice
48. Redefining Interleukin 11 as a regeneration-limiting hepatotoxin
49. Fibroblast-specific IL11 signaling is required for lung fibrosis and inflammation
50. Interleukin-11 is a therapeutic target in idiopathic pulmonary fibrosis
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