142 results on '"Wichmann, Erich"'
Search Results
2. Protein-altering germline mutations implicate novel genes related to lung cancer development
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Ji, Xuemei, Mukherjee, Semanti, Landi, Maria Teresa, Bosse, Yohan, Joubert, Philippe, Zhu, Dakai, Gorlov, Ivan, Xiao, Xiangjun, Han, Younghun, Gorlova, Olga, Hung, Rayjean J., Brhane, Yonathan, Carreras-Torres, Robert, Christiani, David C., Caporaso, Neil, Johansson, Mattias, Liu, Geoffrey, Bojesen, Stig E., Le Marchand, Loic, Albanes, Demetrios, Bickeböller, Heike, Aldrich, Melinda C., Bush, William S., Tardon, Adonina, Rennert, Gad, Chen, Chu, Byun, Jinyoung, Dragnev, Konstantin H., Field, John K., Kiemeney, Lambertus FA., Lazarus, Philip, Zienolddiny, Shan, Lam, Stephen, Schabath, Matthew B., Andrew, Angeline S., Bertazzi, Pier A., Pesatori, Angela C., Diao, Nancy, Su, Li, Song, Lei, Zhang, Ruyang, Leighl, Natasha, Johansen, Jakob S., Mellemgaard, Anders, Saliba, Walid, Haiman, Christopher, Wilkens, Lynne, Fernandez-Somoano, Ana, Fernandez-Tardon, Guillermo, Heijden, Erik H. F. M. van der, Kim, Jin Hee, Davies, Michael P. A., Marcus, Michael W., Brunnström, Hans, Manjer, Jonas, Melander, Olle, Muller, David C., Overvad, Kim, Trichopoulou, Antonia, Tumino, Rosario, Goodman, Gary E., Cox, Angela, Taylor, Fiona, Woll, Penella, Wichmann, Erich, Muley, Thomas, Risch, Angela, Rosenberger, Albert, Grankvist, Kjell, Johansson, Mikael, Shepherd, Frances, Tsao, Ming-Sound, Arnold, Susanne M., Haura, Eric B., Bolca, Ciprian, Holcatova, Ivana, Janout, Vladimir, Kontic, Milica, Lissowska, Jolanta, Mukeria, Anush, Ognjanovic, Simona, Orlowski, Tadeusz M., Scelo, Ghislaine, Swiatkowska, Beata, Zaridze, David, Bakke, Per, Skaug, Vidar, Butler, Lesley M., Offit, Kenneth, Srinivasan, Preethi, Bandlamudi, Chaitanya, Hellmann, Matthew D., Solit, David B., Robson, Mark E., Rudin, Charles M., Stadler, Zsofia K., Taylor, Barry S., Berger, Michael F., Houlston, Richard, McLaughlin, John, Stevens, Victoria, Nickle, David C., Obeidat, Ma’en, Timens, Wim, Artigas, María Soler, Shete, Sanjay, Brenner, Hermann, Chanock, Stephen, Brennan, Paul, McKay, James D., and Amos, Christopher I.
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- 2020
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3. Increased risk of lung cancer in individuals with a family history of the disease: A pooled analysis from the International Lung Cancer Consortium
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Coté, Michele L., Liu, Mei, Bonassi, Stefano, Neri, Monica, Schwartz, Ann G., Christiani, David C., Spitz, Margaret R., Muscat, Joshua E., Rennert, Gad, Aben, Katja K., Andrew, Angeline S., Bencko, Vladimir, Bickeböller, Heike, Boffetta, Paolo, Brennan, Paul, Brenner, Hermann, Duell, Eric J., Fabianova, Eleonora, Field, John K., Foretova, Lenka, Friis, Søren, Harris, Curtis C., Holcatova, Ivana, Hong, Yun-Chul, Isla, Dolores, Janout, Vladimir, Kiemeney, Lambertus A., Kiyohara, Chikako, Lan, Qing, Lazarus, Philip, Lissowska, Jolanta, Le Marchand, Loic, Mates, Dana, Matsuo, Keitaro, Mayordomo, Jose I., McLaughlin, John R., Morgenstern, Hal, Müeller, Heiko, Orlow, Irene, Park, Bernard J., Pinchev, Mila, Raji, Olaide Y., Rennert, Hedy S., Rudnai, Peter, Seow, Adeline, Stucker, Isabelle, Szeszenia-Dabrowska, Neonila, Dawn Teare, M., Tjønnelan, Anne, Ugolini, Donatella, van der Heijden, Henricus F.M., Wichmann, Erich, Wiencke, John K., Woll, Penella J., Yang, Ping, Zaridze, David, Zhang, Zuo-Feng, Etzel, Carol J., and Hung, Rayjean J.
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- 2012
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4. Natural and Orthogonal Interaction Framework for Modeling Gene-Environment Interactions with Application to Lung Cancer
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Ma, Jianzhong, Xiao, Feifei, Xiong, Momiao, Andrew, Angeline S., Brenner, Hermann, Duell, Eric J., Haugen, Aage, Hoggart, Clive, Hung, Rayjean J., Lazarus, Philip, Liu, Changlu, Matsuo, Keitaro, Mayordomo, Jose Ignacio, Schwartz, Ann G., Staratschek-Jox, Andrea, Wichmann, Erich, Yang, Ping, and Amos, Christopher I.
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- 2012
5. Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption
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Schumann, Gunter, Coin, Lachlan J., Lourdusamy, Anbarasu, Charoen, Pimphen, Berger, Karen H., Stacey, David, Desrivières, Sylvane, Aliev, Fazil A., Khan, Anokhi A., Amin, Najaf, Aulchenko, Yurii S., Bakalkin, Georgy, Bakker, Stephan J., Balkau, Beverley, Beulens, Joline W., Bilbao, Ainhoa, de Boer, Rudolf A., Beury, Delphine, Bots, Michiel L., Breetvelt, Elemi J., Cauchi, Stéphane, Cavalcanti-Proença, Christine, Chambers, John C., Clarke, Toni-Kim, Dahmen, Norbert, de Geus, Eco J., Dick, Danielle, Ducci, Francesca, Easton, Alanna, Edenberg, Howard J., Esk, Tõnu, Fernández-Medarde, Alberto, Foroud, Tatiana, Freimer, Nelson B., Girault, Jean-Antoine, Grobbee, Diederick E., Guarrera, Simonetta, Gudbjartsson, Daniel F., Hartikainen, Anna-Liisa, Heath, Andrew C., Hesselbrock, Victor, Hofman, Albert, Hottenga, Jouke-Jan, Isohanni, Matti K., Kaprio, Jaakko, Khaw, Kay-Tee, Kuehnel, Brigitte, Laitinen, Jaana, Lobbens, Stéphane, Luan, Jian'an, Mangino, Massimo, Maroteaux, Matthieu, Matullo, Giuseppe, McCarthy, Mark I., Mueller, Christian, Navis, Gerjan, Numans, Mattijs E., Núñez, Alejandro, Nyholt, Dale R., Onland-Moret, Charlotte N., Oostra, Ben A., O'Reilly, Paul F., Palkovits, Miklos, Penninx, Brenda W., Polidoro, Silvia, Pouta, Anneli, Prokopenko, Inga, Ricceri, Fulvio, Santos, Eugenio, Smit, Johannes H., Soranzo, Nicole, Song, Kijoung, Sovio, Ulla, Stumvoll, Michael, Surakk, Ida, Thorgeirsson, Thorgeir E., Thorsteinsdottir, Unnur, Troakes, Claire, Tyrfingsson, Thorarinn, Tönjes, Anke, Uiterwaal, Cuno S., Uitterlinden, Andre G., van der Harst, Pim, van der Schouw, Yvonne T., Staehlin, Oliver, Vogelzangs, Nicole, Vollenweider, Peter, Waeber, Gerard, Wareham, Nicholas J., Waterworth, Dawn M., Whitfield, John B., Wichmann, Erich H., Willemsen, Gonneke, Witteman, Jacqueline C., Yuan, Xin, Zhai, Guangju, Zhao, Jing H., Zhang, Weihua, Martin, Nicholas G., Metspalu, Andres, Doering, Angela, Scott, James, Spector, Tim D., Loos, Ruth J., Boomsma, Dorret I., Mooser, Vincent, Peltonen, Leena, Stefansson, Kari, van Duijn, Cornelia M., Vineis, Paolo, Sommer, Wolfgang H., Kooner, Jaspal S., Spanagel, Rainer, Heberlein, Ulrike A., Jarvelin, Marjo-Riitta, Elliott, Paul, and Singer, Burton H.
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- 2011
6. Physical activity and sedentary behavior; mechanistic insights and role in disease prevention
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Hoed, Marcel den, primary, Wang, Zhe, additional, Emmerich, Andrew, additional, Pillon, Nicolas, additional, Moore, Timothy, additional, Hemerich, Daiane, additional, Cornelis, Marilyn, additional, Mazzaferro, Eugenia, additional, Broos, Siacia, additional, Ameur, Adam, additional, Bandinelli, Stefania, additional, Bis, Joshua, additional, Boehnke, Michael, additional, Bouchard, Claude, additional, Chasman, Daniel, additional, de Geus, Eco, additional, Deldicque, Louise, additional, Dörr, Marcus, additional, Evans, Michele, additional, Ferrucci, Luigi, additional, Fornage, Myriam, additional, Fox, Caroline, additional, Garland, Theodore, additional, Gyllensten, Ulf, additional, Hansen, Torben, additional, Hayward, Caroline, additional, Horta, Bernardo, additional, Hypponen, Elina, additional, Johnson, W. Craig, additional, Kardia, Sharon, additional, Kiemeney, Lambertus, additional, Laakso, Markku, additional, Langenberg, Claudia, additional, Lehtimäki, Terho, additional, Marchand, Loic Le, additional, Magnusson, Patrik, additional, Martin, Nicholas, additional, Melbye, Mads, additional, Metspalu, Andres, additional, Meyre, David, additional, North, Kari, additional, Ohlsson, Claes, additional, Oldehinkel, Albertine, additional, Orho-Melander, Marju, additional, Pare, Guillaume, additional, Park, Taesung, additional, Pedersen, Oluf, additional, Penninx, Brenda, additional, Pers, Tune, additional, Polasek, Ozren, additional, Prokopenko, Inga, additional, Rotimi, Charles, additional, Samani, Nilesh, additional, Sim, Xueling, additional, Smith, George Davey, additional, Snieder, Harold, additional, Sorensen, Thorkild, additional, Spector, Tim, additional, Timpson, Nicholas, additional, Dam, Rob van, additional, Velde, Nathalie van der, additional, Vollenweider, Peter, additional, Völzke, Henry, additional, Voortman, Trudy, additional, Waeber, Gerard, additional, Wareham, Nick, additional, Weir, David, additional, Wichmann, Erich, additional, Wilson, James, additional, Hevener, Andrea, additional, Krook, Anna, additional, Zierath, Juleen, additional, Thomis, Martine, additional, and Loos, Ruth, additional
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- 2021
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7. Genome-wide interaction analysis identified low-frequency variants with sex disparity in lung cancer risk
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Li, Yafang, primary, Xiao, Xiangjun, additional, Li, Jianrong, additional, Byun, Jinyoung, additional, Cheng, Chao, additional, Bossé, Yohan, additional, McKay, James, additional, Albanes, Demetrius, additional, Lam, Stephen, additional, Tardon, Adonina, additional, Chen, Chu, additional, Bojesen, Stig, additional, Landi, Maria, additional, Johansson, Mattias, additional, Risch, Angela, additional, Bickeböller, Heike, additional, Wichmann, Erich, additional, Christiani, David, additional, Rennert, Gad, additional, Arnold, Susanne, additional, Goodman, Gary, additional, Field, John, additional, Shete, Sanjay, additional, Marchand, Loic Le, additional, Melander, Olle, additional, Brunnström, Hans, additional, Liu, Geoffrey, additional, Hung, Rayjean, additional, Andrew, Angeline, additional, Kiemeney, Lambertus, additional, Shen, Hongbing, additional, Sun, Ryan, additional, Zienolddiny, Shanbeh, additional, Grankvist, Kjell, additional, Johansson, Mikael, additional, Caporaso, Neil, additional, Teare, Dawn, additional, Hong, Yun-Chul, additional, Davies, Michael, additional, Lazarus, Philip, additional, Schabath, Matthew, additional, Aldrich, Melinda, additional, Schwartz, Ann, additional, Gorlov, Ivan, additional, Purrington, Kristen, additional, Yang, Ping, additional, Han, Younghun, additional, Bailey-Wilson, Joan, additional, Liu, Yanhong, additional, Pinney, Susan, additional, Mandal, Diptasri, additional, Willey, James, additional, Gaba, Colette, additional, Brennan, Paul, additional, and Amos, Christopher, additional
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- 2021
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8. Loss-of-Function Mutations in the Filaggrin Gene and Allergic Contact Sensitization to Nickel
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Novak, Natalija, Baurecht, Hansjörg, Schäfer, Torsten, Rodriguez, Elke, Wagenpfeil, Stefan, Klopp, Norman, Heinrich, Joachim, Behrendt, Heidrun, Ring, Johannes, Wichmann, Erich, Illig, Thomas, and Weidinger, Stephan
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- 2008
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9. Is prevention of atopic eczema with hydrolyzed formulas cost-effective? A health economic evaluation from Germany
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Mertens, Janina, Stock, Stephanie, Lüngen, Markus, Berg, Andrea v., Krämer, Ursula, Filipiak-Pittroff, Birgit, Heinrich, Joachim, Koletzko, Sibylle, Grübl, Armin, Wichmann, Erich H., Bauer, Carl P., Reinhardt, Dietrich, Berdel, Dietrich, and Gerber, Andreas
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- 2012
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10. Acute air pollution effects on heart rate variability are modified by SNPs involved in cardiac rhythm in individuals with diabetes or impaired glucose tolerance
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Hampel, Regina, Breitner, Susanne, Schneider, Alexandra, Zareba, Wojciech, Kraus, Ute, Cyrys, Josef, Geruschkat, Uta, Belcredi, Petra, Müller, Martina, Wichmann, -Erich H., and Peters, Annette
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- 2012
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11. New gene functions in megakaryopoiesis and platelet formation
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Gieger, Christian, Radhakrishnan, Aparna, Cvejic, Ana, Tang, Weihong, Porcu, Eleonora, Pistis, Giorgio, Serbanovic-Canic, Jovana, Elling, Ulrich, Goodall, Alison H., Labrune, Yann, Lopez, Lorna M., Mägi, Reedik, Meacham, Stuart, Okada, Yukinori, Pirastu, Nicola, Sorice, Rossella, Teumer, Alexander, Voss, Katrin, Zhang, Weihua, Ramirez-Solis, Ramiro, Bis, Joshua C., Ellinghaus, David, Gögele, Martin, Hottenga, Jouke-Jan, Langenberg, Claudia, Kovacs, Peter, O’Reilly, Paul F., Shin, So-Youn, Esko, Tõnu, Hartiala, Jaana, Kanoni, Stavroula, Murgia, Federico, Parsa, Afshin, Stephens, Jonathan, van der Harst, Pim, Ellen van der Schoot, C., Allayee, Hooman, Attwood, Antony, Balkau, Beverley, Bastardot, François, Basu, Saonli, Baumeister, Sebastian E., Biino, Ginevra, Bomba, Lorenzo, Bonnefond, Amélie, Cambien, François, Chambers, John C., Cucca, Francesco, D’Adamo, Pio, Davies, Gail, de Boer, Rudolf A., de Geus, Eco J. C., Döring, Angela, Elliott, Paul, Erdmann, Jeanette, Evans, David M., Falchi, Mario, Feng, Wei, Folsom, Aaron R., Frazer, Ian H., Gibson, Quince D., Glazer, Nicole L., Hammond, Chris, Hartikainen, Anna-Liisa, Heckbert, Susan R., Hengstenberg, Christian, Hersch, Micha, Illig, Thomas, Loos, Ruth J. F., Jolley, Jennifer, Tee Khaw, Kay, Kühnel, Brigitte, Kyrtsonis, Marie-Christine, Lagou, Vasiliki, Lloyd-Jones, Heather, Lumley, Thomas, Mangino, Massimo, Maschio, Andrea, Mateo Leach, Irene, McKnight, Barbara, Memari, Yasin, Mitchell, Braxton D., Montgomery, Grant W., Nakamura, Yusuke, Nauck, Matthias, Navis, Gerjan, Nöthlings, Ute, Nolte, Ilja M., Porteous, David J., Pouta, Anneli, Pramstaller, Peter P., Pullat, Janne, Ring, Susan M., Rotter, Jerome I., Ruggiero, Daniela, Ruokonen, Aimo, Sala, Cinzia, Samani, Nilesh J., Sambrook, Jennifer, Schlessinger, David, Schreiber, Stefan, Schunkert, Heribert, Scott, James, Smith, Nicholas L., Snieder, Harold, Starr, John M., Stumvoll, Michael, Takahashi, Atsushi, Tang, Wilson W.H., Taylor, Kent, Tenesa, Albert, Lay Thein, Swee, Tönjes, Anke, Uda, Manuela, Ulivi, Sheila, van Veldhuisen, Dirk J., Visscher, Peter M., Völker, Uwe, Wichmann, Erich H., Wiggins, Kerri L., Willemsen, Gonneke, Yang, Tsun-Po, Hua Zhao, Jing, Zitting, Paavo, Bradley, John R., Dedoussis, George V., Gasparini, Paolo, Hazen, Stanley L., Metspalu, Andres, Pirastu, Mario, Shuldiner, Alan R., Joost van Pelt, L., Zwaginga, Jaap-Jan, Boomsma, Dorret I., Deary, Ian J., Franke, Andre, Froguel, Philippe, Ganesh, Santhi K., Jarvelin, Marjo-Riitta, Martin, Nicholas G., Meisinger, Christa, Psaty, Bruce M., Spector, Timothy D., Wareham, Nicholas J., Akkerman, Jan-Willem N., Ciullo, Marina, Deloukas, Panos, Greinacher, Andreas, Jupe, Steve, Kamatani, Naoyuki, Khadake, Jyoti, Kooner, Jaspal S., Penninger, Josef, Prokopenko, Inga, Stemple, Derek, Toniolo, Daniela, Wernisch, Lorenz, Sanna, Serena, Hicks, Andrew A., Rendon, Augusto, Ferreira, Manuel A., Ouwehand, Willem H., and Soranzo, Nicole
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- 2011
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12. Passive smoking and behavioural problems in children: Results from the LISAplus prospective birth cohort study
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Tiesler, Carla M.T., Chen, Chih-Mei, Sausenthaler, Stefanie, Herbarth, Olf, Lehmann, Irina, Schaaf, Beate, Krämer, Ursula, von Berg, Andrea, von Kries, Rüdiger, Wichmann, -Erich H., and Heinrich, Joachim
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- 2011
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13. Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk
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Ehret, Georg B., Munroe, Patricia B., Rice, Kenneth M., Bochud, Murielle, Johnson, Andrew D., Chasman, Daniel I., Smith, Albert V., Tobin, Martin D., Verwoert, Germaine C., Hwang, Shih-Jen, Pihur, Vasyl, Vollenweider, Peter, O’Reilly, Paul F., Amin, Najaf, Bragg-Gresham, Jennifer L., Teumer, Alexander, Glazer, Nicole L., Launer, Lenore, Zhao, Jing Hua, Aulchenko, Yurii, Heath, Simon, Sõber, Siim, Parsa, Afshin, Luan, Jian’an, Arora, Pankaj, Dehghan, Abbas, Zhang, Feng, Lucas, Gavin, Hicks, Andrew A., Jackson, Anne U., Peden, John F, Tanaka, Toshiko, Wild, Sarah H., Rudan, Igor, Igl, Wilmar, Milaneschi, Yuri, Parker, Alex N., Fava, Cristiano, Chambers, John C., Fox, Ervin R., Kumari, Meena, Go, Min Jin, van der Harst, Pim, Kao, Wen Hong Linda, Sjögren, Marketa, Vinay, D. G., Alexander, Myriam, Tabara, Yasuharu, Shaw-Hawkins, Sue, Whincup, Peter H., Liu, Yongmei, Shi, Gang, Kuusisto, Johanna, Tayo, Bamidele, Seielstad, Mark, Sim, Xueling, Nguyen, Khanh-Dung Hoang, Lehtimäki, Terho, Matullo, Giuseppe, Wu, Ying, Gaunt, Tom R., Onland-Moret, Charlotte N., Cooper, Matthew N., Platou, Carl G. P., Org, Elin, Hardy, Rebecca, Dahgam, Santosh, Palmen, Jutta, Vitart, Veronique, Braund, Peter S., Kuznetsova, Tatiana, Uiterwaal, Cuno S. P. M., Adeyemo, Adebowale, Palmas, Walter, Campbell, Harry, Ludwig, Barbara, Tomaszewski, Maciej, Tzoulaki, Ioanna, Palmer, Nicholette D., Aspelund, Thor, Garcia, Melissa, Chang, Yen-Pei C., O’Connell, Jeffrey R., Steinle, Nanette I., Grobbee, Diederick E., Arking, Dan E., Kardia, Sharon L., Morrison, Alanna C., Hernandez, Dena, Najjar, Samer, McArdle, Wendy L., Hadley, David, Brown, Morris J., Connell, John M., Hingorani, Aroon D., Day, Ian N.M., Lawlor, Debbie A., Beilby, John P., Lawrence, Robert W., Clarke, Robert, Hopewell, Jemma C., Ongen, Halit, Dreisbach, Albert W., Li, Yali, Young, Hunter J., Bis, Joshua C., Kähönen, Mika, Viikari, Jorma, Adair, Linda S., Lee, Nanette R., Chen, Ming-Huei, Olden, Matthias, Pattaro, Cristian, Bolton, Judith A. Hoffman, Köttgen, Anna, Bergmann, Sven, Mooser, Vincent, Chaturvedi, Nish, Frayling, Timothy M., Islam, Muhammad, Jafar, Tazeen H., Erdmann, Jeanette, Kulkarni, Smita R., Bornstein, Stefan R., Grässler, Jürgen, Groop, Leif, Voight, Benjamin F., Kettunen, Johannes, Howard, Philip, Taylor, Andrew, Guarrera, Simonetta, Ricceri, Fulvio, Emilsson, Valur, Plump, Andrew, Barroso, Inês, Khaw, Kay-Tee, Weder, Alan B., Hunt, Steven C., Sun, Yan V., Bergman, Richard N., Collins, Francis S., Bonnycastle, Lori L., Scott, Laura J., Stringham, Heather M., Peltonen, Leena, Perola, Markus, Vartiainen, Erkki, Brand, Stefan-Martin, Staessen, Jan A., Wang, Thomas J., Burton, Paul R., Artigas, Maria Soler, Dong, Yanbin, Snieder, Harold, Wang, Xiaoling, Zhu, Haidong, Lohman, Kurt K., Rudock, Megan E., Heckbert, Susan R., Smith, Nicholas L., Wiggins, Kerri L., Doumatey, Ayo, Shriner, Daniel, Veldre, Gudrun, Viigimaa, Margus, Kinra, Sanjay, Prabhakaran, Dorairaj, Tripathy, Vikal, Langefeld, Carl D., Rosengren, Annika, Thelle, Dag S., Corsi, Anna Maria, Singleton, Andrew, Forrester, Terrence, Hilton, Gina, McKenzie, Colin A., Salako, Tunde, Iwai, Naoharu, Kita, Yoshikuni, Ogihara, Toshio, Ohkubo, Takayoshi, Okamura, Tomonori, Ueshima, Hirotsugu, Umemura, Satoshi, Eyheramendy, Susana, Meitinger, Thomas, Wichmann, Erich H., Cho, Yoon Shin, Kim, Hyung-Lae, Lee, Jong-Young, Scott, James, Sehmi, Joban S., Zhang, Weihua, Hedblad, Bo, Nilsson, Peter, Smith, George Davey, Wong, Andrew, Narisu, Narisu, Stančáková, Alena, Raffel, Leslie J., Yao, Jie, Kathiresan, Sekar, O’Donnell, Christopher J., Schwartz, Stephen M., Ikram, Arfan M., Longstreth, W. T., Jr, Mosley, Thomas H., Seshadri, Sudha, Shrine, Nick R.G., Wain, Louise V., Morken, Mario A., Swift, Amy J., Laitinen, Jaana, Prokopenko, Inga, Zitting, Paavo, Cooper, Jackie A., Humphries, Steve E., Danesh, John, Rasheed, Asif, Goel, Anuj, Hamsten, Anders, Watkins, Hugh, Bakker, Stephan J. L., van Gilst, Wiek H., Janipalli, Charles S., Mani, Radha K., Yajnik, Chittaranjan S., Hofman, Albert, Mattace-Raso, Francesco U. S., Oostra, Ben A., Demirkan, Ayse, Isaacs, Aaron, Rivadeneira, Fernando, Lakatta, Edward G., Orru, Marco, Scuteri, Angelo, Ala-Korpela, Mika, Kangas, Antti J., Lyytikäinen, Leo-Pekka, Soininen, Pasi, Tukiainen, Taru, Würtz, Peter, Ong, Rick Twee-Hee, Dörr, Marcus, Kroemer, Heyo K., Völker, Uwe, Völzke, Henry, Galan, Pilar, Hercberg, Serge, Lathrop, Mark, Zelenika, Diana, Deloukas, Panos, Mangino, Massimo, Spector, Tim D., Zhai, Guangju, Meschia, James F., Nalls, Michael A., Sharma, Pankaj, Terzic, Janos, Kumar, Kranthi M. V., Denniff, Matthew, Zukowska-Szczechowska, Ewa, Wagenknecht, Lynne E., Fowkes, Gerald F.R., Charchar, Fadi J., Schwarz, Peter E. H., Hayward, Caroline, Guo, Xiuqing, Rotimi, Charles, Bots, Michiel L., Brand, Eva, Samani, Nilesh J., Polasek, Ozren, Talmud, Philippa J., Nyberg, Fredrik, Kuh, Diana, Laan, Maris, Hveem, Kristian, Palmer, Lyle J., van der Schouw, Yvonne T., Casas, Juan P., Mohlke, Karen L., Vineis, Paolo, Raitakari, Olli, Ganesh, Santhi K., Wong, Tien Y., Tai, Shyong E, Cooper, Richard S., Laakso, Markku, Rao, Dabeeru C., Harris, Tamara B., Morris, Richard W., Dominiczak, Anna F., Kivimaki, Mika, Marmot, Michael G., Miki, Tetsuro, Saleheen, Danish, Chandak, Giriraj R., Coresh, Josef, Navis, Gerjan, Salomaa, Veikko, Han, Bok-Ghee, Zhu, Xiaofeng, Kooner, Jaspal S., Melander, Olle, Ridker, Paul M, Bandinelli, Stefania, Gyllensten, Ulf B., Wright, Alan F., Wilson, James F., Ferrucci, Luigi, Farrall, Martin, Tuomilehto, Jaakko, Pramstaller, Peter P., Elosua, Roberto, Soranzo, Nicole, Sijbrands, Eric J. G., Altshuler, David, Loos, Ruth J. F., Shuldiner, Alan R., Gieger, Christian, Meneton, Pierre, Uitterlinden, Andre G., Wareham, Nicholas J., Gudnason, Vilmundur, Rotter, Jerome I., Rettig, Rainer, Uda, Manuela, Strachan, David P., Witteman, Jacqueline C. M., Hartikainen, Anna-Liisa, Beckmann, Jacques S., Boerwinkle, Eric, Vasan, Ramachandran S., Boehnke, Michael, Larson, Martin G., Järvelin, Marjo-Riitta, Psaty, Bruce M., Abecasis, Gonçalo R., Chakravarti, Aravinda, Elliott, Paul, van Duijn, Cornelia M., Newton-Cheh, Christopher, Levy, Daniel, Caulfield, Mark J., and Johnson, Toby
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- 2011
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14. Human metabolic individuality in biomedical and pharmaceutical research
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Suhre, Karsten, Shin, So-Youn, Petersen, Ann-Kristin, Mohney, Robert P., Meredith, David, Wägele, Brigitte, Altmaier, Elisabeth, CARDIoGRAM, Deloukas, Panos, Erdmann, Jeanette, Grundberg, Elin, Hammond, Christopher J., de Angelis, Martin Hrabé, Kastenmüller, Gabi, Köttgen, Anna, Kronenberg, Florian, Mangino, Massimo, Meisinger, Christa, Meitinger, Thomas, Mewes, Hans-Werner, Milburn, Michael V., Prehn, Cornelia, Raffler, Johannes, Ried, Janina S., Römisch-Margl, Werner, Samani, Nilesh J., Small, Kerrin S., Wichmann, Erich H., Zhai, Guangju, Illig, Thomas, Spector, Tim D., Adamski, Jerzy, Soranzo, Nicole, and Gieger, Christian
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- 2011
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15. Relative weight-related costs of healthcare use by children—Results from the two German birth cohorts, GINI-plus and LISA-plus
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Breitfelder, Ariane, Wenig, Christina M., Wolfenstetter, Silke B., Rzehak, Peter, Menn, Petra, John, Jürgen, Leidl, Reiner, Bauer, Carl Peter, Koletzko, Sibylle, Röder, Stefan, Herbarth, Olf, von Berg, Andrea, Berdel, Dietrich, Krämer, Ursula, Schaaf, Beate, Wichmann, -Erich H., and Heinrich, Joachim
- Published
- 2011
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16. An integrated genome research network for studying the genetics of alcohol addiction
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Spanagel, Rainer, Bartsch, Dusan, Brors, Bendikt, Dahmen, Norbert, Deussing, Jan, Eils, Roland, Ende, Gabriele, Gallinat, Jürgen, Gebicke-Haerter, Peter, Heinz, Andreas, Kiefer, Falk, Jäger, Willi, Mann, Karl, Matthäus, Franziska, Nöthen, Markus, Rietschel, Marcella, Sartorius, Alexander, Schütz, Günther, Sommer, Wolfgang H., Sprengel, Rolf, Walter, Henrik, Wichmann, Erich, Wienker, Thomas, Wurst, Wolfgang, and Zimmer, Andreas
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- 2010
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17. European lactase persistence genotype shows evidence of association with increase in body mass index
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Kettunen, Johannes, Silander, Kaisa, Saarela, Olli, Amin, Najaf, Müller, Martina, Timpson, Nicholas, Surakka, Ida, Ripatti, Samuli, Laitinen, Jaana, Hartikainen, Anna-Liisa, Pouta, Anneli, Lahermo, Päivi, Anttila, Verneri, Männistö, Satu, Jula, Antti, Virtamo, Jarmo, Salomaa, Veikko, Lehtimäki, Terho, Raitakari, Olli, Gieger, Christian, Wichmann, Erich H., Van Duijn, Cornelia M., Smith, George Davey, McCarthy, Mark I., Järvelin, Marjo-Riitta, Perola, Markus, and Peltonen, Leena
- Published
- 2010
18. Genome-wide Association Study of Alcohol Dependence
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Treutlein, Jens, Cichon, Sven, Ridinger, Monika, Wodarz, Norbert, Soyka, Michael, Zill, Peter, Maier, Wolfgang, Moessner, Rainald, Gaebel, Wolfgang, Dahmen, Norbert, Fehr, Christoph, Scherbaum, Norbert, Steffens, Michael, Ludwig, Kerstin U., Frank, Josef, Wichmann, Erich H., Schreiber, Stefan, Dragano, Nico, Sommer, Wolfgang H., Leonardi-Essmann, Fernando, Lourdusamy, Anbarasu, Gebicke-Haerter, Peter, Wienker, Thomas F., Sullivan, Patrick F., Nöthen, Markus M., Kiefer, Falk, Spanagel, Rainer, Mann, Karl, and Rietschel, Marcella
- Published
- 2009
- Full Text
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19. Fibrinogen Genes Modify the Fibrinogen Response to Ambient Particulate Matter
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Peters, Annette, Greven, Sonja, Heid, Iris M., Baldari, Fiammetta, Breitner, Susanne, Bellander, Tom, Chrysohoou, Christina, Illig, Thomas, Jacquemin, Bénédicte, Koenig, Wolfgang, Lanki, Timo, Nyberg, Fredrik, Pekkanen, Juha, Pistelli, Riccardo, Rückerl, Regina, Stefanadis, Christodoulos, Schneider, Alexandra, Sunyer, Jordi, and Wichmann, Erich H.
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- 2009
- Full Text
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20. Variants in the neuronal nitric oxide synthase (nNOS, NOS1) gene are associated with restless legs syndrome
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Winkelmann, Juliane, Lichtner, Peter, Schormair, Barbara, Uhr, Manfred, Hauk, Stephanie, Stiasny-Kolster, Karin, Trenkwalder, Claudia, Paulus, Walter, Peglau, Ines, Eisensehr, Ilonka, Illig, Thomas, Wichmann, Erich H., Pfister, Hildegard, Golic, Jelena, Bettecken, Thomas, Pütz, Benno, Holsboer, Florian, Meitinger, Thomas, and Müller-Myhsok, Bertram
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- 2008
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21. IL-6 promoter polymorphisms and quantitative traits related to the metabolic syndrome in KORA S4
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Grallert, Harald, Huth, Cornelia, Kolz, Melanie, Meisinger, Christa, Herder, Christian, Strassburger, Klaus, Giani, Guido, Wichmann, -Erich H., Adamski, Jerzy, Illig, Thomas, and Rathmann, Wolfgang
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- 2006
- Full Text
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22. Air Pollution and Markers of Inflammation and Coagulation in Patients with Coronary Heart Disease
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Rückerl, Regina, Ibald-Mulli, Angela, Koenig, Wolfgang, Schneider, Alexandra, Woelke, Gabriele, Cyrys, Josef, Heinrich, Joachim, Marder, Victor, Frampton, Mark, Wichmann, Erich H., and Peters, Annette
- Published
- 2006
- Full Text
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23. ALOX5AP Gene and the PDE4D Gene in a Central European Population of Stroke Patients
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Lõhmussaar, Elin, Gschwendtner, Andreas, Mueller, Jakob C., Org, Tõnis, Wichmann, Erich, Hamann, Gerhard, Meitinger, Thomas, and Dichgans, Martin
- Published
- 2005
- Full Text
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24. Allergies in high-risk schoolchildren after early intervention with cowʼs milk protein hydrolysates: 10-year results from the German Infant Nutritional Intervention (GINI) study
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von Berg, Andrea, Filipiak-Pittroff, Birgit, Krämer, Ursula, Hoffmann, Barbara, Link, Elke, Beckmann, Christina, Hoffmann, Ute, Reinhardt, Dietrich, Grübl, Armin, Heinrich, Joachim, Wichmann, -Erich H., Bauer, Carl- P., Koletzko, Sibylle, and Berdel, Dietrich
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- 2013
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25. The effect of hydrolyzed cowʼs milk formula for allergy prevention in the first year of life: The German Infant Nutritional Intervention Study, a randomized double-blind trial
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von Berg, Andrea, Koletzko, Sibylle, Grübl, Armin, Filipiak-Pittroff, Birgit, Wichmann, -Erich H., Bauer, Carl Peter, Reinhardt, Dietrich, and Berdel, Dietrich
- Published
- 2003
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26. Different effects of endotoxin versus mite and cat allergen exposure on T-cell differentiation in infants
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Bolte, Gabriele, Krauss-Etschmann, Susanne, Konstantopoulos, Nikolaos, Bischof, Wolfgang, Fahlbusch, Bärbel, Schendel, Dolores J., Wichmann, Erich H, and Heinrich, Joachim
- Published
- 2002
27. Exposure to endotoxin decreases the risk of atopic eczema in infancy: A cohort study
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Gehring, Ulrike, Bolte, Gabriele, Borte, Michael, Bischof, Wolfgang, Fahlbusch, Bärbel, Wichmann, -Erich H., and Heinrich, Joachim
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- 2001
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28. Decline of Ambient Air Pollution and Respiratory Symptoms in Children
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HEINRICH, JOACHIM, HOELSCHER, BERND, and WICHMANN, ERICH H.
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- 2000
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29. Die Rolle der Luftschadstoffe fr die Gesundheit
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Peters, Annette, primary, Hoffmann, Barbara, additional, Brunekreef, Bert, additional, Knzli, Nino, additional, Kutlar Joss, Metlem, additional, Probst-Hensch, Nicole, additional, Ritz, Beate, additional, Straif, Kurt, additional, and Wichmann, Erich, additional
- Published
- 2019
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30. Les effets des polluants atmosphriques sur la sant
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Peters, Annette, primary, Hoffmann, Barbara, additional, Brunekreef, Bert, additional, Knzli, Nino, additional, Kutlar Joss, Metlem, additional, Probst-Hensch, Nicole, additional, Ritz, Beate, additional, Straif, Kurt, additional, and Wichmann, Erich, additional
- Published
- 2019
- Full Text
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31. Histologic types of lung carcinoma and age at onset
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Kreuzer, Michaela, Kreienbrock, Lothar, Muller, Klaus M., Gerken, Michael, and Wichmann, Erich
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Lung cancer -- Demographic aspects ,Health - Published
- 1999
32. Effect of Cadmium Body Burden on Immune Response of School Children
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RITZ, BEATE, HEINRICH, JOACHIM, WJST, MATTHIAS, WICHMANN, ERICH, and KRAUSE, CHRISTIAN
- Published
- 1998
33. Migraine without aura: genome-wide association analysis identifies several novel susceptibility
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de Vries, Boukje, Freilinger, Tobias, Anttila, Verneri, Malik, Rainer, Kallela, Mikko, Terwindt, Gisela M, Pozo-Rosich, Patricia, Winsvold, Bendik, Nyholt, Dale R, van Oosterhout, Willebrordus PJ, Artto, Ville, Todt, Unda, Hämäläinen, Eija, Fernández-Morales, Jèssica, Louter, Mark A, Kaunisto, Mari A, Schoenen, Jean, Raitakari, Olli, Lehtimäki, Terho, Vila-Pueyo, Marta, Göbel, Hartmut, Wichmann, Erich, Sintas, Cèlia, Uitterlinden, Andre G, Hofman, Albert, Rivadeneira, Fernando, Heinze, Axel, Tronvik, Erling, van Duijn, Cornelia M, Kaprio, Jaakko, Cormand, Bru, Wessman, Maija, Frants, Rune R, Meitinger, Thomas, Müller-Myhsok, Bertram, Zwart, John-Anker, Färkkilä, Markus, Macaya, Alfons, Ferrari, Michel D, Kubisch, Christian, Palotie, Aarno, Dichgans, Martin, van den Maagdenberg, Arn MJM, and International Headache Genetics Consortium
- Published
- 2013
- Full Text
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34. The effect of continuous G-CSF application in human cyclic neutropenia: a model analysis
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Schmitz, Stephan, Franke, Horst, Wichmann, Erich H., and Diehl, Volker
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- 1995
35. Konstruktionen in Stein und Beton
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Wichmann, Erich and Wichmann, Erich
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- 1932
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36. Konstruktionen in Eisenbeton
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Wichmann, Erich and Wichmann, Erich
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- 1932
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37. Konstruktionen in Stahl
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Wichmann, Erich and Wichmann, Erich
- Published
- 1932
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38. Konstruktionen in Holz
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Wichmann, Erich and Wichmann, Erich
- Published
- 1932
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39. Large-Scale Candidate Gene Analysis in Whites and African-Americans Identifies IL6R Polymorphism in Relation to Atrial Fibrillation: The NHLBI CARe Project
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Schnabel, Renate B., Kerr, Kathleen F., Lubitz, Steven A., Alkylbekova, Ermeg L., Marcus, Gregory M., Sinner, Moritz F., Magnani, Jared W., Wolf, Philip A., Deo, Rajat, Lloyd-Jones, Donald M., Lunetta, Kathryn L., Mehra, Reena, Levy, Daniel, Fox, Ervin R., Arking, Dan E., Mosley, Thomas H., Mueller, Martina, Young, Taylor, Wichmann, Erich, Seshadri, Sudha, Farlow, Deborah N., Rotter, Jerome I., Soliman, Elsayed Z., Glazer, Nicole L., Wilson, James G., Breteler, Monique M.B., Sotoodehnia, Nona, Newton-Cheh, Christopher, Kääb, Stefan, Ellinor, Patrick T., Alonso, Alvaro, Benjamin, Emelia J., and Heckbert, Susan R.
- Subjects
Male ,Middle Aged ,Polymorphism, Single Nucleotide ,Receptors, Interleukin-6 ,Article ,United States ,White People ,Black or African American ,Cohort Studies ,Stroke ,Risk Factors ,Atrial Fibrillation ,Humans ,Female ,Chromosomes, Human, Pair 4 ,National Heart, Lung, and Blood Institute (U.S.) ,Alleles ,Aged - Abstract
The genetic background of atrial fibrillation (AF) in whites and African Americans is largely unknown. Genes in cardiovascular pathways have not been systematically investigated.We examined a panel of approximately 50,000 common single-nucleotide polymorphisms (SNPs) in 2095 cardiovascular candidate genes and AF in 3 cohorts with participants of European (n=18,524; 2260 cases) or African American descent (n=3662; 263 cases) in the National Heart, Lung, and Blood Institute's Candidate Gene Association Resource. Results in whites were followed up in the German Competence Network for AF (n=906, 468 cases). The top result was assessed in relation to incident ischemic stroke in the Cohorts for Heart and Aging Research in Genomic Epidemiology Stroke Consortium (n=19,602 whites, 1544 incident strokes). SNP rs4845625 in the IL6R gene was associated with AF (relative risk [RR] C allele, 0.90; 95% confidence interval [CI], 0.85-0.95; P=0.0005) in whites but did not reach statistical significance in African Americans (RR, 0.86; 95% CI, 0.72-1.03; P=0.09). The results were comparable in the German AF Network replication, (RR, 0.71; 95% CI, 0.57-0.89; P=0.003). No association between rs4845625 and stroke was observed in whites. The known chromosome 4 locus near PITX2 in whites also was associated with AF in African Americans (rs4611994; hazard ratio, 1.40; 95% CI, 1.16-1.69; P=0.0005).In a community-based cohort meta-analysis, we identified genetic association in IL6R with AF in whites. Additionally, we demonstrated that the chromosome 4 locus known from recent genome-wide association studies in whites is associated with AF in African Americans.
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- 2011
40. Genome-wide association study identifies five loci associated with lung function
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Repapi, Emmanouela, Sayers, Ian, Wain, Louise V, Burton, Paul R, Johnson, Toby, Obeidat, Ma'en, Zhao, Jing Hua, Ramasamy, Adaikalavan, Zhai, Guangju, Vitart, Veronique, Huffman, Jennifer E, Igl, Wilmar, Albrecht, Eva, Deloukas, Panos, Henderson, John, Granell, Raquel, McArdle, Wendy L, Rudnicka, Alicja R, Barroso, Inês, Loos, Ruth J F, Wareham, Nicholas J, Mustelin, Linda, Rantanen, Taina, Surakka, Ida, Imboden, Medea, H Wichmann, Erich, Grković, Ivica, Janković, Stipan, Zgaga, Lina, Hartikainen, Anna-Liisa, Peltonen, Leena, Gyllensten, Ulf, Johansson, Åsa, Zaboli, Ghazal, Campbell, Harry, Wild, Sarah H, Wilson, James F, Glaser, Sven, Homuth, Georg, Völzke, Henry, Mangino, Massimo, Soranzo, Nicole, Spector, Tim D, Polašek, Ozren, Rudan, Igor, Wright, Alan F, Heliövaara, Markku, Ripati, Samuli, Pouta, Anneli, Naluai, Åsa Torinsson, Olin, Anna-Carin, Torén, Kjell, Cooper, Matthew N, James, Alan L, Palmer, Lyle J, Hingorani, Aroon D, Wannamethee, S Goya, Whincup, Peter H, Davey Smith, George, Ebrahim, Shah, McKeever, Tricia M, Pavord, Ian D, MacLeod, Andrew K, Morris, Andrew D, Porteous, David J, Cooper, Cyrus, Dennison, Elaine, Shaheen, Seif, Karrasch, Stefan, Schnabel, Eva, Schulz, Holger, Grallert, Harald, Bouatia-Naji, Nabila, Delplanque, Jérôme, Froguel, Philippe, Blakey, John D, Britton, John R, Morris, Richard W, Holloway, John W, Lawlor, Debbie A, Hui, Jennie, Nyberg, Fredrik, Jarvelin, Marjo-Riitta, Jackson, Cathy, Kähönen, Mika, Kaprio, Jaakko, Probst-Hensch, Nicole M, Koch, Beate, Hayward, Caroline, Evans, David M, Elliot, Paul, Strachan, David P, Hall, Ian P, and Tobin, Martin D
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respiratory system ,genome-wide association study ,lung function - Abstract
Pulmonary function measures are heritable traits that predict morbidity and mortality and define chronic obstructive pulmonary disease (COPD). We tested genome-wide association with forced expiratory volume in 1 s (FEV1) and the ratio of FEV1 to forced vital capacity (FVC) in the SpiroMeta consortium (n = 20, 288 individuals of European ancestry). We conducted a meta-analysis of top signals with data from direct genotyping (n ≤ 32, 184 additional individuals) and in silico summary association data from the CHARGE Consortium (n = 21, 209) and the Health 2000 survey (n ≤ 883). We confirmed the reported locus at 4q31 and identified associations with FEV1 or FEV1/FVC and common variants at five additional loci: 2q35 in TNS1 (P = 1.11 × 10−12), 4q24 in GSTCD (2.18 × 10−23), 5q33 in HTR4 (P = 4.29 × 10−9), 6p21 in AGER (P = 3.07 × 10−15) and 15q23 in THSD4 (P = 7.24 × 10−15). mRNA analyses showed expression of TNS1, GSTCD, AGER, HTR4 and THSD4 in human lung tissue. These associations offer mechanistic insight into pulmonary function regulation and indicate potential targets for interventions to alleviate respiratory disease.
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- 2010
41. Genome-wide association study of alcohol dependence
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Treutlein, Jens, Cichon, Sven, Ridinger, Monika, Wodarz, Norbert, Soyka, Michael, Maier, W., Moessner, Richhild, Dahmen, Norbert, Fehr, Cindy, Scherbaum, Norbert, Wichmann, Erich, Schreiber, S., Dragano, Nico, Hofsommer, Wolfgang, Wienker, Thomas F., Sullivan, Philip F., Nothen, M., Kiefer, Falk, Spanagel, Rainer, Mann, Karl F., and Rietschel, Marcella
- Subjects
Medizin - Published
- 2010
42. Informatics and Medicine
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Kuhn, Klaus, Knoll, Alois, Mewes, Hans-Werner, Schwaiger, Markus, Bode, Arndt, Broy, Manfred, Hannelore, Daniel, Feussner, Hubertus, Gradinger, Reiner, Hauner, Hans, Höfler, Heinz, Holzmann, Bernhard, Horsch, Alexander, Kemper, Alfons, Krcmar, Helmut, Kochs, Eberhard F., Lange, Rüdiger, Leidl, Reiner, Mansmann, Ulrich, Mayr, Ernst W., Meitinger, Thomas, Molls, Michael, Navab, Nassir, Nüsslin, Fridtjof, Peschel, Christian, Reiser, Maximilian, Ring, Johannes, Rummeny, Ernst J., Schlichter, Johann, Schmid, Roland, Wichmann, Erich, and Ziegler, Sibylle
- Subjects
ComputingMilieux_COMPUTERSANDEDUCATION ,InformationSystems_MISCELLANEOUS ,ddc - Abstract
In order to translate scientific results from bench to bedside and further into an evidence-based and efficient health system, intensive collaboration is needed between experts from medicine, biology, informatics, engineering, public health, as well as social and economic sciences. Research challenges can be attributed to four areas: bioinformatics and systems biology, biomedical engineering and informatics, health informatics and individual healthcare, and public health informatics. In order to bridge existing gaps between different disciplines and cultures, we suggest focusing on interdisciplinary education, taking an integrative approach and starting interdisciplinary practice at early stages of education.
- Published
- 2007
43. Leitfaden für Baukunde insbesondere für Stahlbau
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Wichmann, Erich, primary
- Published
- 1932
- Full Text
- View/download PDF
44. Empfehlungen zur Umsetzung der Approbationsordnung für Ärzte vom 27.06.2002 in den Fächern Epidemiologie, Medizinische Biometrie und Medizinische Informatik
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Hilgers, Ralf-Dieter, Feldmann, Uwe, Jöckel, Karl-Heinz, Klar, Rüdiger, Rienhoff, Otto, Schäfer, Helmut, Selbmann, Hans-Konrad, and Wichmann, Erich
- Subjects
medical biometry ,Epidemologie ,Approbationsordnung Medizin ,ddc: 610 ,medizinische Biometrie ,Medizin ,medical informatics ,epidemiology ,medizinische Informatik ,medical curriculum Germany - Abstract
In the Approbationsordnung für Ärzte (German regulation for the Curriculum in Medicine) of 27th June, 2002 the disciplines Epidemiology, Medical Biometry and Medical Informatics are combined in one obligatory cross-sectional subject of the second part of the medical exam. In addition, it is possible to study topics from these disciplines in more detail on a voluntary basis. The aim of teaching this cross-sectional subject is to qualify the students to assess their own actions critically, to apply recommendations with care, and to learn to use tools like systematic documentation and modern information technology.For the mentioned disciplines a catalogue has been developed which is subdivided in three parts. In the first part methods are described which are needed to support medical decisions. The second part refers to support of medical supply and quality management, whereas the third part deals with the basic elements of Public Health and Health Economics, with respect to causation of diseases and prevention. Mit der Approbationsordnung für Ärzte vom 27. Juni 2002 werden die Disziplinen Epidemiologie, Medizinische Biometrie und Medizinische Informatik zum prüfungspflichtigen Querschnittsfach für den 2. Abschnitt der ärztlichen Prüfung zusammengefasst. Darüber hinaus besteht die Möglichkeit Lehrinhalte aus diesem Fächerkanon intensiver als Wahlfach zu studieren. Das Ziel der Lehre im Querschnittsbereich ist es, die Studierenden zur kritischen Beurteilung des eigenen Handelns, zur kritischen Anwendung fremder Empfehlungen, zur systematischen Dokumentation und zum Umgang mit modernen Werkzeugen der Informationstechnologie im Rahmen der Berufsausübung zu befähigen. Für die genannten Disziplinen wurde ein Gegenstandskatalog entwickelt, der sich in drei Teilbereiche gliedert. In einem ersten Bereich werden die für die Unterstützung ärztlicher Entscheidungen notwendigen Methoden dargestellt. Der zweite Bereich bezieht sich auf die Unterstützung der ärztlichen Versorgungsaufgaben und des ärztlichen Qualitätsmanagements, während in einem dritten Teil die Grundelemente bevölkerungsbezogener und gesundheitsökonomischer Aspekte des ärztlichen Handelns in Hinblick auf Krankheitsursachen und Prävention dargestellt werden.
- Published
- 2005
45. Extensive natural variation for cellular hydrogen peroxide release is genetically controlled
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Attar, Homa, Bedard, Karen, Migliavacca, Eugenia, Gagnebin, Maryline, Dupré, Yann, Descombes, Patrick, Borel, Christelle, Deutsch, Samuel, Prokisch, Holger, Meitinger, Thomas, Mehta, Divya, Wichmann, Erich, Delabar, Jean Maurice, Dermitzakis, Emmanouil T., Krause, Karl Heinz, Antonarakis, Stylianos E., Attar, Homa, Bedard, Karen, Migliavacca, Eugenia, Gagnebin, Maryline, Dupré, Yann, Descombes, Patrick, Borel, Christelle, Deutsch, Samuel, Prokisch, Holger, Meitinger, Thomas, Mehta, Divya, Wichmann, Erich, Delabar, Jean Maurice, Dermitzakis, Emmanouil T., Krause, Karl Heinz, and Antonarakis, Stylianos E.
- Abstract
Natural variation in DNA sequence contributes to individual differences in quantitative traits. While multiple studies have shown genetic control over gene expression variation, few additional cellular traits have been investigated. Here, we investigated the natural variation of NADPH oxidase-dependent hydrogen peroxide (H2O2 release), which is the joint effect of reactive oxygen species (ROS) production, superoxide metabolism and degradation, and is related to a number of human disorders. We assessed the normal variation of H2O2 release in lymphoblastoid cell lines (LCL) in a family-based 3-generation cohort (CEPH-HapMap), and in 3 population-based cohorts (KORA, GenCord, HapMap). Substantial individual variation was observed, 45% of which were associated with heritability in the CEPH-HapMap cohort. We identified 2 genome-wide significant loci of Hsa12 and Hsa15 in genome-wide linkage analysis. Next, we performed genome-wide association study (GWAS) for the combined KORA-GenCord cohorts (n = 279) using enhanced marker resolution by imputation (>1.4 million SNPs). We found 5 significant associations (p<5.00×10-8) and 54 suggestive associations (p<1.00×10-5), one of which confirmed the linked region on Hsa15. To replicate our findings, we performed GWAS using 58 HapMap individuals and ~2.1 million SNPs. We identified 40 genome-wide significant and 302 suggestive SNPs, and confirmed genome signals on Hsa1, Hsa12, and Hsa15. Genetic loci within 900 kb from the known candidate gene p67phox on Hsa1 were identified in GWAS in both cohorts. We did not find replication of SNPs across all cohorts, but replication within the same genomic region. Finally, a highly significant decrease in H2O2 release was observed in Down Syndrome (DS) individuals (p<2.88×10-12). Taken together, our results show strong evidence of genetic control of H2O2 in LCL of healthy and DS cohorts and suggest that c
- Published
- 2012
46. Correction for Schumann et al., Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption (Proceedings of the National Academy Sciences of the United States of America (2011) 108, 17, (7119-7124))
- Author
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Schumann, Gunter, Coin, Lachlan J., Lourdusamy, Anbarasu, Charoen, Pimphen, Berger, Karen H., Stacey, David, Desrivières, Sylvane, Aliev, Fazil A., Khan, Anokhi A., Amin, Najaf, Aulchenko, Yurii S., Bakalkin, Georgy, Bakker, Stephan J., Balkau, Beverley, Beulens, Joline W., Bilbao, Ainhoa, De Boer, Rudolf A., Beury, Delphine, Bots, Michiel L., Breetvelt, Elemi J., Cauchi, Stéphane, Cavalcanti-Proença, Christine, Chambers, John C., Clarke, Toni Kim, Dahmen, Norbert, De Geus, Eco J., Dick, Danielle, Ducci, Francesca, Easton, Alanna, Edenberg, Howard J., Esk, Tõnu, Fernández-Medarde, Alberto, Foroud, Tatiana, Freimer, Nelson B., Girault, Jean Antoine, Grobbee, Diederick E., Guarrera, Simonetta, Gudbjartsson, Daniel F., Hartikainen, Anna Liisa, Heath, Andrew C., Hesselbrock, Victor, Hofman, Albert, Hottenga, Jouke Jan, Isohanni, Matti K., Kaprio, Jaakko, Khaw, Kay Tee, Kuehnel, Brigitte, Laitinen, Jaana, Lobbens, Stéphane, Luan, Jian'an, Mangino, Massimo, Maroteaux, Matthieu, Matullo, Giuseppe, McCarthy, Mark I., Mueller, Christian, Navis, Gerjan, Numans, Mattijs E., Núñez, Alejandro, Nyholt, Dale R., Onland-Moret, Charlotte N., Oostra, Ben A., O'Reilly, Paul F., Palkovits, Miklos, Penninx, Brenda W., Polidoro, Silvia, Pouta, Anneli, Prokopenko, Inga, Ricceri, Fulvio, Santos, Eugenio, Smit, Johannes H., Soranzo, Nicole, Song, Kijoung, Sovio, Ulla, Stumvoll, Michael, Surakk, Ida, Thorgeirsson, Thorgeir E., Thorsteinsdottir, Unnur, Troakes, Claire, Tyrfingsson, Thorarinn, Tönjes, Anke, Uiterwaal, Cuno S., Uitterlinden, Andre G., Van Der Harst, Pim, Van Der Schouw, Yvonne T., Staehlin, Oliver, Vogelzangs, Nicole, Vollenweider, Peter, Waeber, Gerard, Wareham, Nicholas J., Waterworth, Dawn M., Whitfield, John B., Wichmann, Erich H., Willemsen, Gonneke, Witteman, Jacqueline C., Yuan, Xin, Zhai, Guangju, Zhao, Jing H., Zhang, Weihua, Martin, Nicholas G., Metspalu, Andres, Doering, Angela, Scott, James, Spector, Tim D., Loos, Ruth J., Boomsma, Dorret I., Mooser, Vincent, Peltonen, Leena, Stefansson, Kari, Van Duijn, Cornelia M., Vineis, Paolo, Sommer, Wolfgang H., Kooner, Jaspal S., Spanagel, Rainer, Heberlein, Ulrike A., Jarvelin, Marjo Riitta, Elliott, Paul, Schumann, Gunter, Coin, Lachlan J., Lourdusamy, Anbarasu, Charoen, Pimphen, Berger, Karen H., Stacey, David, Desrivières, Sylvane, Aliev, Fazil A., Khan, Anokhi A., Amin, Najaf, Aulchenko, Yurii S., Bakalkin, Georgy, Bakker, Stephan J., Balkau, Beverley, Beulens, Joline W., Bilbao, Ainhoa, De Boer, Rudolf A., Beury, Delphine, Bots, Michiel L., Breetvelt, Elemi J., Cauchi, Stéphane, Cavalcanti-Proença, Christine, Chambers, John C., Clarke, Toni Kim, Dahmen, Norbert, De Geus, Eco J., Dick, Danielle, Ducci, Francesca, Easton, Alanna, Edenberg, Howard J., Esk, Tõnu, Fernández-Medarde, Alberto, Foroud, Tatiana, Freimer, Nelson B., Girault, Jean Antoine, Grobbee, Diederick E., Guarrera, Simonetta, Gudbjartsson, Daniel F., Hartikainen, Anna Liisa, Heath, Andrew C., Hesselbrock, Victor, Hofman, Albert, Hottenga, Jouke Jan, Isohanni, Matti K., Kaprio, Jaakko, Khaw, Kay Tee, Kuehnel, Brigitte, Laitinen, Jaana, Lobbens, Stéphane, Luan, Jian'an, Mangino, Massimo, Maroteaux, Matthieu, Matullo, Giuseppe, McCarthy, Mark I., Mueller, Christian, Navis, Gerjan, Numans, Mattijs E., Núñez, Alejandro, Nyholt, Dale R., Onland-Moret, Charlotte N., Oostra, Ben A., O'Reilly, Paul F., Palkovits, Miklos, Penninx, Brenda W., Polidoro, Silvia, Pouta, Anneli, Prokopenko, Inga, Ricceri, Fulvio, Santos, Eugenio, Smit, Johannes H., Soranzo, Nicole, Song, Kijoung, Sovio, Ulla, Stumvoll, Michael, Surakk, Ida, Thorgeirsson, Thorgeir E., Thorsteinsdottir, Unnur, Troakes, Claire, Tyrfingsson, Thorarinn, Tönjes, Anke, Uiterwaal, Cuno S., Uitterlinden, Andre G., Van Der Harst, Pim, Van Der Schouw, Yvonne T., Staehlin, Oliver, Vogelzangs, Nicole, Vollenweider, Peter, Waeber, Gerard, Wareham, Nicholas J., Waterworth, Dawn M., Whitfield, John B., Wichmann, Erich H., Willemsen, Gonneke, Witteman, Jacqueline C., Yuan, Xin, Zhai, Guangju, Zhao, Jing H., Zhang, Weihua, Martin, Nicholas G., Metspalu, Andres, Doering, Angela, Scott, James, Spector, Tim D., Loos, Ruth J., Boomsma, Dorret I., Mooser, Vincent, Peltonen, Leena, Stefansson, Kari, Van Duijn, Cornelia M., Vineis, Paolo, Sommer, Wolfgang H., Kooner, Jaspal S., Spanagel, Rainer, Heberlein, Ulrike A., Jarvelin, Marjo Riitta, and Elliott, Paul
- Abstract
The authors note that, due to a printer's error, the author name Tõnu Esk should have appeared as Tõnu Esko. The online version has been corrected.
- Published
- 2011
47. Genome-wide association study of migraine implicates a common susceptibility variant on 8q22.1
- Author
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Anttila, Verneri, Stefansson, Hreinn, Kallela, Mikko, Todt, Unda, Terwindt, Gisela M., Calafato, M. Stella, Nyholt, Dale R., Dimas, Antigone S., Freilinger, Tobias, Mueller-Myhsok, Bertram, Artto, Ville, Inouye, Michael, Alakurtti, Kirsi, Kaunisto, Mari A., Haemaelaeinen, Eija, de Vries, Boukje, Stam, Anine H., Weller, Claudia M., Heinze, Axel, Heinze-Kuhn, Katja, Goebel, Ingrid, Borck, Guntram, Goebel, Hartmut, Steinberg, Stacy, Wolf, Christiane, Bjoernsson, Asgeir, Gudmundsson, Gretar, Kirchmann, Malene, Hauge, Anne, Werge, Thomas, Schoenen, Jean, Eriksson, Johan G., Hagen, Knut, Stovner, Lars, Wichmann, Erich, Meitinger, Thomas, Alexander, Michael, Moebus, Susanne, Schreiber, Stefan, Aulchenko, Yurii S., Breteler, Monique M. B., Uitterlinden, Andre G., Hofman, Albert, van Duijn, Cornelia M., Tikka-Kleemola, Paevi, Vepsaelaeinen, Salli, Lucae, Susanne, Tozzi, Federica, Muglia, Pierandrea, Barrett, Jeffrey, Kaprio, Jaakko, Faerkkilae, Markus, Peltonen, Leena, Stefansson, Kari, Zwart, John-Anker, Ferrari, Michel D., Olesen, Jes, Daly, Mark, Wessman, Maija, van den Maagdenberg, Arn M. J. M., Dichgans, Martin, Kubisch, Christian, Dermitzakis, Emmanouil T., Frants, Rune R., Palotie, Aarno, Anttila, Verneri, Stefansson, Hreinn, Kallela, Mikko, Todt, Unda, Terwindt, Gisela M., Calafato, M. Stella, Nyholt, Dale R., Dimas, Antigone S., Freilinger, Tobias, Mueller-Myhsok, Bertram, Artto, Ville, Inouye, Michael, Alakurtti, Kirsi, Kaunisto, Mari A., Haemaelaeinen, Eija, de Vries, Boukje, Stam, Anine H., Weller, Claudia M., Heinze, Axel, Heinze-Kuhn, Katja, Goebel, Ingrid, Borck, Guntram, Goebel, Hartmut, Steinberg, Stacy, Wolf, Christiane, Bjoernsson, Asgeir, Gudmundsson, Gretar, Kirchmann, Malene, Hauge, Anne, Werge, Thomas, Schoenen, Jean, Eriksson, Johan G., Hagen, Knut, Stovner, Lars, Wichmann, Erich, Meitinger, Thomas, Alexander, Michael, Moebus, Susanne, Schreiber, Stefan, Aulchenko, Yurii S., Breteler, Monique M. B., Uitterlinden, Andre G., Hofman, Albert, van Duijn, Cornelia M., Tikka-Kleemola, Paevi, Vepsaelaeinen, Salli, Lucae, Susanne, Tozzi, Federica, Muglia, Pierandrea, Barrett, Jeffrey, Kaprio, Jaakko, Faerkkilae, Markus, Peltonen, Leena, Stefansson, Kari, Zwart, John-Anker, Ferrari, Michel D., Olesen, Jes, Daly, Mark, Wessman, Maija, van den Maagdenberg, Arn M. J. M., Dichgans, Martin, Kubisch, Christian, Dermitzakis, Emmanouil T., Frants, Rune R., and Palotie, Aarno
- Abstract
Migraine is a common episodic neurological disorder, typically presenting with recurrent attacks of severe headache and autonomic dysfunction. Apart from rare monogenic subtypes, no genetic or molecular markers for migraine have been convincingly established. We identified the minor allele of rs1835740 on chromosome 8q22.1 to be associated with migraine (P = 5.38 x 10(-9), odds ratio = 1.23, 95% CI 1.150-1.324) in a genome-wide association study of 2,731 migraine cases ascertained from three European headache clinics and 10,747 population-matched controls. The association was replicated in 3,202 cases and 40,062 controls for an overall meta-analysis P value of 1.69 x 10(-11) (odds ratio = 1.18, 95% CI 1.127-1.244). rs1835740 is located between MTDH (astrocyte elevated gene 1, also known as AEG-1) and PGCP (encoding plasma glutamate carboxypeptidase). In an expression quantitative trait study in lymphoblastoid cell lines, transcript levels of the MTDH were found to have a significant correlation to rs1835740 (P = 3.96 x 10(-5), permuted threshold for genome-wide significance 7.7 x 10(-5)). To our knowledge, our data establish rs1835740 as the first genetic risk factor for migraine.
- Published
- 2010
48. Genome-wide association study identifies eight loci associated with blood pressure
- Author
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Newton-Cheh, Christopher, Johnson, Toby, Gateva, Vesela, Tobin, D, Bochud, Murielle, Coin, Lachlan, Najjar, S, Zhao, Hua, Heath, C, Eyheramendy, Susana, Papadakis, Konstantinos, Voight, F, Scott, J, Zhang, Feng, Farrall, Martin, Tanaka, Toshiko, Wallace, Chris, Chambers, C, Khaw, Kay-Tee, Nilsson, Peter, van der Harst, Pim, Polidoro, Silvia, Grobbee, E, Onland-Moret, Charlotte, Bots, L, Wain, V, Elliott, S, Teumer, Alexander, Luan, Jian'an, Lucas, Gavin, Kuusisto, Johanna, Burton, R, Hadley, David, McArdle, L, Brown, Morris, Dominiczak, Anna, Newhouse, J, Samani, J, Webster, John, Zeggini, Eleftheria, Beckmann, S, Bergmann, Sven, Lim, Noha, Song, Kijoung, Vollenweider, Peter, Waeber, Gerard, Waterworth, M, Yuan, Xin, Groop, Leif, Orho-Melander, Marju, Allione, Alessandra, Di Gregorio, Alessandra, Guarrera, Simonetta, Panico, Salvatore, Ricceri, Fulvio, Romanazzi, Valeria, Sacerdote, Carlotta, Vineis, Paolo, Barroso, Ines, Sandhu, S, Luben, N, Crawford, J, Jousilahti, Pekka, Perola, Markus, Boehnke, Michael, Bonnycastle, L, Collins, S, Jackson, U, Mohlke, L, Stringham, M, Valle, T, Willer, J, Bergman, N, Morken, A, Doering, Angela, Gieger, Christian, Illig, Thomas, Meitinger, Thomas, Org, Elin, Pfeufer, Arne, Wichmann, Erich, Kathiresan, Sekar, Marrugat, Jaume, O'Donnell, J, Schwartz, M, Siscovick, S, Subirana, Isaac, Freimer, B, Hartikainen, Anna-Liisa, McCarthy, I, O'Reilly, F, Peltonen, Leena, Pouta, Anneli, de Jong, E, Snieder, Harold, van Gilst, H, Clarke, Robert, Goel, Anuj, Hamsten, Anders, Peden, F, Seedorf, Udo, Syvänen, Ann-Christine, Tognoni, Giovanni, Lakatta, G, Sanna, Serena, Scheet, Paul, Schlessinger, David, Scuteri, Angelo, Doerr, Marcus, Ernst, Florian, Felix, B, Homuth, Georg, Lorbeer, Roberto, Reffelmann, Thorsten, Rettig, Rainer, Voelker, Uwe, Galan, Pilar, Gut, G, Hercberg, Serge, Lathrop, Mark, Zelenika, Diana, Deloukas, Panos, Soranzo, Nicole, Williams, M, Zhai, Guangju, Salomaa, Veikko, Laakso, Markku, Elosua, Roberto, Forouhi, G, Volzke, Henry, Uiterwaal, S, van der Schouw, T, Numans, E, Matullo, Giuseppe, Navis, Gerjan, Berglund, Goran, Bingham, A, Kooner, S, Connell, M, Bandinelli, Stefania, Ferrucci, Luigi, Watkins, Hugh, Spector, D, Tuomilehto, Jaakko, Altshuler, David, Strachan, P, Laan, Maris, Meneton, Pierre, Wareham, J, Uda, Manuela, Jarvelin, Marjo-Riitta, Mooser, Vincent, Melander, Olle, Loos, F, Elliott, Paul, Abecasis, R, Caulfield, Mark, Munroe, Patricia B., Newton-Cheh, Christopher, Johnson, Toby, Gateva, Vesela, Tobin, D, Bochud, Murielle, Coin, Lachlan, Najjar, S, Zhao, Hua, Heath, C, Eyheramendy, Susana, Papadakis, Konstantinos, Voight, F, Scott, J, Zhang, Feng, Farrall, Martin, Tanaka, Toshiko, Wallace, Chris, Chambers, C, Khaw, Kay-Tee, Nilsson, Peter, van der Harst, Pim, Polidoro, Silvia, Grobbee, E, Onland-Moret, Charlotte, Bots, L, Wain, V, Elliott, S, Teumer, Alexander, Luan, Jian'an, Lucas, Gavin, Kuusisto, Johanna, Burton, R, Hadley, David, McArdle, L, Brown, Morris, Dominiczak, Anna, Newhouse, J, Samani, J, Webster, John, Zeggini, Eleftheria, Beckmann, S, Bergmann, Sven, Lim, Noha, Song, Kijoung, Vollenweider, Peter, Waeber, Gerard, Waterworth, M, Yuan, Xin, Groop, Leif, Orho-Melander, Marju, Allione, Alessandra, Di Gregorio, Alessandra, Guarrera, Simonetta, Panico, Salvatore, Ricceri, Fulvio, Romanazzi, Valeria, Sacerdote, Carlotta, Vineis, Paolo, Barroso, Ines, Sandhu, S, Luben, N, Crawford, J, Jousilahti, Pekka, Perola, Markus, Boehnke, Michael, Bonnycastle, L, Collins, S, Jackson, U, Mohlke, L, Stringham, M, Valle, T, Willer, J, Bergman, N, Morken, A, Doering, Angela, Gieger, Christian, Illig, Thomas, Meitinger, Thomas, Org, Elin, Pfeufer, Arne, Wichmann, Erich, Kathiresan, Sekar, Marrugat, Jaume, O'Donnell, J, Schwartz, M, Siscovick, S, Subirana, Isaac, Freimer, B, Hartikainen, Anna-Liisa, McCarthy, I, O'Reilly, F, Peltonen, Leena, Pouta, Anneli, de Jong, E, Snieder, Harold, van Gilst, H, Clarke, Robert, Goel, Anuj, Hamsten, Anders, Peden, F, Seedorf, Udo, Syvänen, Ann-Christine, Tognoni, Giovanni, Lakatta, G, Sanna, Serena, Scheet, Paul, Schlessinger, David, Scuteri, Angelo, Doerr, Marcus, Ernst, Florian, Felix, B, Homuth, Georg, Lorbeer, Roberto, Reffelmann, Thorsten, Rettig, Rainer, Voelker, Uwe, Galan, Pilar, Gut, G, Hercberg, Serge, Lathrop, Mark, Zelenika, Diana, Deloukas, Panos, Soranzo, Nicole, Williams, M, Zhai, Guangju, Salomaa, Veikko, Laakso, Markku, Elosua, Roberto, Forouhi, G, Volzke, Henry, Uiterwaal, S, van der Schouw, T, Numans, E, Matullo, Giuseppe, Navis, Gerjan, Berglund, Goran, Bingham, A, Kooner, S, Connell, M, Bandinelli, Stefania, Ferrucci, Luigi, Watkins, Hugh, Spector, D, Tuomilehto, Jaakko, Altshuler, David, Strachan, P, Laan, Maris, Meneton, Pierre, Wareham, J, Uda, Manuela, Jarvelin, Marjo-Riitta, Mooser, Vincent, Melander, Olle, Loos, F, Elliott, Paul, Abecasis, R, Caulfield, Mark, and Munroe, Patricia B.
- Abstract
Elevated blood pressure is a common, heritable cause of cardiovascular disease worldwide. To date, identification of common genetic variants influencing blood pressure has proven challenging. We tested 2.5 million genotyped and imputed SNPs for association with systolic and diastolic blood pressure in 34,433 subjects of European ancestry from the Global BPgen consortium and followed up findings with direct genotyping (N ≤ 71,225 European ancestry, N ≤ 12,889 Indian Asian ancestry) and in silico comparison (CHARGE consortium, N = 29,136). We identified association between systolic or diastolic blood pressure and common variants in eight regions near the CYP17A1 (P = 7 × 10−24), CYP1A2 (P = 1 × 10−23), FGF5 (P = 1 × 10−21), SH2B3 (P = 3 × 10−18), MTHFR (P = 2 × 10−13), c10orf107 (P = 1 × 10−9), ZNF652 (P = 5 × 10−9) and PLCD3 (P = 1 × 10−8) genes. All variants associated with continuous blood pressure were associated with dichotomous hypertension. These associations between common variants and blood pressure and hypertension offer mechanistic insights into the regulation of blood pressure and may point to novel targets for interventions to prevent cardiovascular disease.
- Published
- 2009
- Full Text
- View/download PDF
49. The impact of low emission zone and heavy traffic ban in Munich on the reduction of PM10 in ambient air
- Author
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Cyrys, Josef, primary, Fensterer, Veronika, additional, Küchenhoff, Helmut, additional, Maier, Verena, additional, Wichmann, Erich, additional, Breitner, Susanne, additional, Schneider, Alexandra, additional, and Peters, Annette, additional
- Published
- 2013
- Full Text
- View/download PDF
50. Extensive Natural Variation for Cellular Hydrogen Peroxide Release Is Genetically Controlled
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Attar, Homa, primary, Bedard, Karen, additional, Migliavacca, Eugenia, additional, Gagnebin, Maryline, additional, Dupré, Yann, additional, Descombes, Patrick, additional, Borel, Christelle, additional, Deutsch, Samuel, additional, Prokisch, Holger, additional, Meitinger, Thomas, additional, Mehta, Divya, additional, Wichmann, Erich, additional, Delabar, Jean Maurice, additional, Dermitzakis, Emmanouil T., additional, Krause, Karl-Heinz, additional, and Antonarakis, Stylianos E., additional
- Published
- 2012
- Full Text
- View/download PDF
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