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859 results on '"White, SA"'

5. FoxP2 and Vocalization

Author

White, SA

Abstract

From a linguist’s point of view, the ability to vocalize new sounds may not seem to be a critical component of language. Yet when this ability is impaired, the social and emotional consequences for the affected individual can be severe, as evidenced by those suffering from developmental or injury-related speech disorders. How are we to understand this vocal learning trait and where should it be placed within a framework for language evolution? Here, I argue that studying the supporting brain pathways that are affected in vocal learning disorders is a good place to start. Since such study is largely limited to non-invasive methods in humans, investigating other animals that possess this rare trait paves the way for a comparative analysis of the molecular, cellular and synaptic basis of vocal production learning, including human speech. Such inquiry can highlight shared evolutionary pathways as well as key detours.

Published
2023

6. Mice with Dab1 or Vldlr insufficiency exhibit abnormal neonatal vocalization patterns.

Author

Fraley, ER, Burkett, ZD, Day, NF, Schwartz, BA, Phelps, PE, and White, SA

Subjects
Animals, Animals, Newborn, Mice, Serine Endopeptidases, Cell Adhesion Molecules, Neuronal, LDL-Receptor Related Proteins, Receptors, LDL, Nerve Tissue Proteins, Extracellular Matrix Proteins, Vocalization, Animal, Genotype, Gene Dosage, Pediatric, Basic Behavioral and Social Science, Behavioral and Social Science, Brain Disorders, Autism, Genetics, Intellectual and Developmental Disabilities (IDD), Mental Health, 2.1 Biological and endogenous factors, Newborn, Cell Adhesion Molecules, Neuronal, Receptors, LDL, Vocalization, Animal, Biochemistry and Cell Biology, Other Physical Sciences
Abstract

Genetic and epigenetic changes in components of the Reelin-signaling pathway (RELN, DAB1) are associated with autism spectrum disorder (ASD) risk. Social communication deficits are a key component of the ASD diagnostic criteria, but the underlying neurogenetic mechanisms remain unknown. Reln insufficient mice exhibit ASD-like behavioral phenotypes including altered neonatal vocalization patterns. Reelin affects multiple pathways including through the receptors, Very low-density lipoprotein receptor (Vldlr), Apolipoprotein receptor 2 (Apoer2), and intracellular signaling molecule Disabled-1 (Dab1). As Vldlr was previously implicated in avian vocalization, here we investigate vocalizations of neonatal mice with a reduction or absence of these components of the Reelin-signaling pathway. Mice with low or no Dab1 expression exhibited reduced calling rates, altered call-type usage, and differential vocal development trajectories. Mice lacking Vldlr expression also had altered call repertoires, and this effect was exacerbated by deficiency in Apoer2. Together with previous findings, these observations 1) solidify a role for Reelin in vocal communication of multiple species, 2) point to the canonical Reelin-signaling pathway as critical for development of normal neonatal calling patterns in mice, and 3) suggest that mutants in this pathway could be used as murine models for Reelin-associated vocal deficits in humans.

Published
2016

7. FoxP2 and Vocalization

Author

White, SA

Abstract

From a linguist’s point of view, the ability to vocalize new sounds may not seem to be a critical component of language. Yet when this ability is impaired, the social and emotional consequences for the affected individual can be severe, as evidenced by those suffering from developmental or injury-related speech disorders. How are we to understand this vocal learning trait and where should it be placed within a framework for language evolution? Here, I argue that studying the supporting brain pathways that are affected in vocal learning disorders is a good place to start. Since such study is largely limited to non-invasive methods in humans, investigating other animals that possess this rare trait paves the way for a comparative analysis of the molecular, cellular and synaptic basis of vocal production learning, including human speech. Such inquiry can highlight shared evolutionary pathways as well as key detours.

Published
2021

10. Can an old bird change his tune?

Author

White, SA and Mooney, R

Subjects
Prosencephalon, Telencephalon, Neostriatum, Animals, Songbirds, Acoustic Stimulation, Brain Mapping, Vocalization, Animal, Courtship, Learning, Age Factors, Neuronal Plasticity, Tape Recording, Feedback, Pattern Recognition, Automated, Male, Vocalization, Animal, Pattern Recognition, Automated, Developmental Biology, Biological Sciences, Medical and Health Sciences, Psychology and Cognitive Sciences
Abstract

The stereotyped courtship songs of 'age-limited' songbirds, which learn their songs during a specific early period of their lives, were once thought immutable, but recent studies suggest that their maintenance may actually rely on subtle cues provided by auditory feedback.

Published
1999

13. Three gonadotropin-releasing hormone genes in one organism suggest novel roles for an ancient peptide.

Author

White, SA, Kasten, TL, Bond, CT, Adelman, JP, and Fernald, RD

Subjects
Biological Sciences, Genetics, Biotechnology, Neurosciences, Contraception/Reproduction, Underpinning research, 1.1 Normal biological development and functioning, Reproductive health and childbirth, Amino Acid Sequence, Animals, Base Sequence, Cloning, Molecular, DNA Primers, DNA, Complementary, Gonadotropin-Releasing Hormone, In Situ Hybridization, Molecular Sequence Data, Perches, Polymerase Chain Reaction, RNA, Messenger
Abstract

Gonadotropin-releasing hormone (GnRH) is known and named for its essential role in vertebrate reproduction. Release of this decapeptide from neurons in the hypothalamus controls pituitary gonadotropin levels which, in turn, regulate gonadal state. The importance of GnRH is underscored by its widespread expression and conservation across vertebrate taxa: five amino acids are invariant in all nine known forms, whereas two others show only conservative changes. In most eutherian mammals, only one form, expressed in the hypothalamus, is thought to exist, although in a recent report, antibody staining in developing primates suggests an additional form. In contrast, multiple GnRH forms and expression loci have been reported in many non-mammalian vertebrates. However, evidence based on immunological discrimination does not always agree with analysis of gene expression, since GnRH forms encoded by different genes may not be reliably distinguished by antibodies. Here we report the expression of three distinct GnRH genes in a teleost fish brain, including the sequence encoding a novel GnRH preprohormone. Using in situ hybridization, we show that this form is found only in neurons that project to the pituitary and exhibit changes in soma size depending on social and reproductive state. The other two GnRH genes are expressed in other, distinct cell populations. All three genes share the motif of encoding a polypeptide consisting of GnRH and a GnRH-associated peptide. Whereas the GnRH moiety is highly conserved, the GnRH-associated peptides are not, reflecting differential selective pressure on different parts of the gene. GnRH forms expressed in nonhypothalamic regions may serve to coordinate reproductive activities of the animal.

Published
1995

20. 4 Sexual Violence against Peacekeepers and Aid Workers

Author

Dolan-Evans, Elliot, Westendorf, Jasmine-Kim, Jennings, Kathleen M, Mazurana, Dyan, Donnelly, Phoebe, Nyambeki, Leah, Kemp, Ellie, Martin, Sarah, Potts, Alina, White, Sabrina, Connors, Jane, Elderfield, Emily, Bian, Junru, Daigle, Megan, Nasser-Eddin, Nof, Abu-Assab, Nour, Naik, Asmita, Myrttinen, Henri, and Kihara-Hunt, Ai

Published
2024

21. Index

Author

Dolan-Evans, Elliot, Westendorf, Jasmine-Kim, Jennings, Kathleen M, Mazurana, Dyan, Donnelly, Phoebe, Nyambeki, Leah, Kemp, Ellie, Martin, Sarah, Potts, Alina, White, Sabrina, Connors, Jane, Elderfield, Emily, Bian, Junru, Daigle, Megan, Nasser-Eddin, Nof, Abu-Assab, Nour, Naik, Asmita, Myrttinen, Henri, and Kihara-Hunt, Ai

Published
2024

22. 6 The Imperative of Prioritizing Victims' Rights

Author

Dolan-Evans, Elliot, Westendorf, Jasmine-Kim, Jennings, Kathleen M, Mazurana, Dyan, Donnelly, Phoebe, Nyambeki, Leah, Kemp, Ellie, Martin, Sarah, Potts, Alina, White, Sabrina, Connors, Jane, Elderfield, Emily, Bian, Junru, Daigle, Megan, Nasser-Eddin, Nof, Abu-Assab, Nour, Naik, Asmita, Myrttinen, Henri, and Kihara-Hunt, Ai

Published
2024

23. Notes

Author

Dolan-Evans, Elliot, Westendorf, Jasmine-Kim, Jennings, Kathleen M, Mazurana, Dyan, Donnelly, Phoebe, Nyambeki, Leah, Kemp, Ellie, Martin, Sarah, Potts, Alina, White, Sabrina, Connors, Jane, Elderfield, Emily, Bian, Junru, Daigle, Megan, Nasser-Eddin, Nof, Abu-Assab, Nour, Naik, Asmita, Myrttinen, Henri, and Kihara-Hunt, Ai

Published
2024

24. 15 Rethinking PSEA

Author

Dolan-Evans, Elliot, Westendorf, Jasmine-Kim, Jennings, Kathleen M, Mazurana, Dyan, Donnelly, Phoebe, Nyambeki, Leah, Kemp, Ellie, Martin, Sarah, Potts, Alina, White, Sabrina, Connors, Jane, Elderfield, Emily, Bian, Junru, Daigle, Megan, Nasser-Eddin, Nof, Abu-Assab, Nour, Naik, Asmita, Myrttinen, Henri, and Kihara-Hunt, Ai

Published
2024

25. 14 Empowered Aid

Author

Dolan-Evans, Elliot, Westendorf, Jasmine-Kim, Jennings, Kathleen M, Mazurana, Dyan, Donnelly, Phoebe, Nyambeki, Leah, Kemp, Ellie, Martin, Sarah, Potts, Alina, White, Sabrina, Connors, Jane, Elderfield, Emily, Bian, Junru, Daigle, Megan, Nasser-Eddin, Nof, Abu-Assab, Nour, Naik, Asmita, Myrttinen, Henri, and Kihara-Hunt, Ai

Published
2024

26. 13 Agency and Affect in PSEA

Author

Dolan-Evans, Elliot, Westendorf, Jasmine-Kim, Jennings, Kathleen M, Mazurana, Dyan, Donnelly, Phoebe, Nyambeki, Leah, Kemp, Ellie, Martin, Sarah, Potts, Alina, White, Sabrina, Connors, Jane, Elderfield, Emily, Bian, Junru, Daigle, Megan, Nasser-Eddin, Nof, Abu-Assab, Nour, Naik, Asmita, Myrttinen, Henri, and Kihara-Hunt, Ai

Published
2024

27. 12 From ‘Cultural Sensitivity' to ‘Structural Sensitivity'

Author

Dolan-Evans, Elliot, Westendorf, Jasmine-Kim, Jennings, Kathleen M, Mazurana, Dyan, Donnelly, Phoebe, Nyambeki, Leah, Kemp, Ellie, Martin, Sarah, Potts, Alina, White, Sabrina, Connors, Jane, Elderfield, Emily, Bian, Junru, Daigle, Megan, Nasser-Eddin, Nof, Abu-Assab, Nour, Naik, Asmita, Myrttinen, Henri, and Kihara-Hunt, Ai

Published
2024

28. 11 ‘We Don't Have a Word for That': Issues in Translating PSEA Communication

Author

Dolan-Evans, Elliot, Westendorf, Jasmine-Kim, Jennings, Kathleen M, Mazurana, Dyan, Donnelly, Phoebe, Nyambeki, Leah, Kemp, Ellie, Martin, Sarah, Potts, Alina, White, Sabrina, Connors, Jane, Elderfield, Emily, Bian, Junru, Daigle, Megan, Nasser-Eddin, Nof, Abu-Assab, Nour, Naik, Asmita, Myrttinen, Henri, and Kihara-Hunt, Ai

Published
2024

29. Part III Looking Forward: Where to from Here?

Author

Dolan-Evans, Elliot, Westendorf, Jasmine-Kim, Jennings, Kathleen M, Mazurana, Dyan, Donnelly, Phoebe, Nyambeki, Leah, Kemp, Ellie, Martin, Sarah, Potts, Alina, White, Sabrina, Connors, Jane, Elderfield, Emily, Bian, Junru, Daigle, Megan, Nasser-Eddin, Nof, Abu-Assab, Nour, Naik, Asmita, Myrttinen, Henri, and Kihara-Hunt, Ai

Published
2024

30. 9 Power, Consent and Peacekeeping Economies

Author

Dolan-Evans, Elliot, Westendorf, Jasmine-Kim, Jennings, Kathleen M, Mazurana, Dyan, Donnelly, Phoebe, Nyambeki, Leah, Kemp, Ellie, Martin, Sarah, Potts, Alina, White, Sabrina, Connors, Jane, Elderfield, Emily, Bian, Junru, Daigle, Megan, Nasser-Eddin, Nof, Abu-Assab, Nour, Naik, Asmita, Myrttinen, Henri, and Kihara-Hunt, Ai

Published
2024

31. 10 Gender, Race, Sexuality and PSEA

Author

Dolan-Evans, Elliot, Westendorf, Jasmine-Kim, Jennings, Kathleen M, Mazurana, Dyan, Donnelly, Phoebe, Nyambeki, Leah, Kemp, Ellie, Martin, Sarah, Potts, Alina, White, Sabrina, Connors, Jane, Elderfield, Emily, Bian, Junru, Daigle, Megan, Nasser-Eddin, Nof, Abu-Assab, Nour, Naik, Asmita, Myrttinen, Henri, and Kihara-Hunt, Ai

Published
2024

32. 8 Masculinities and Institutional Blind Spots

Author

Dolan-Evans, Elliot, Westendorf, Jasmine-Kim, Jennings, Kathleen M, Mazurana, Dyan, Donnelly, Phoebe, Nyambeki, Leah, Kemp, Ellie, Martin, Sarah, Potts, Alina, White, Sabrina, Connors, Jane, Elderfield, Emily, Bian, Junru, Daigle, Megan, Nasser-Eddin, Nof, Abu-Assab, Nour, Naik, Asmita, Myrttinen, Henri, and Kihara-Hunt, Ai

Published
2024

33. 6A United Nations Victims' Rights Statement

Author

Dolan-Evans, Elliot, Westendorf, Jasmine-Kim, Jennings, Kathleen M, Mazurana, Dyan, Donnelly, Phoebe, Nyambeki, Leah, Kemp, Ellie, Martin, Sarah, Potts, Alina, White, Sabrina, Connors, Jane, Elderfield, Emily, Bian, Junru, Daigle, Megan, Nasser-Eddin, Nof, Abu-Assab, Nour, Naik, Asmita, Myrttinen, Henri, and Kihara-Hunt, Ai

Published
2024

34. 7 Accountability Advocates

Author

Dolan-Evans, Elliot, Westendorf, Jasmine-Kim, Jennings, Kathleen M, Mazurana, Dyan, Donnelly, Phoebe, Nyambeki, Leah, Kemp, Ellie, Martin, Sarah, Potts, Alina, White, Sabrina, Connors, Jane, Elderfield, Emily, Bian, Junru, Daigle, Megan, Nasser-Eddin, Nof, Abu-Assab, Nour, Naik, Asmita, Myrttinen, Henri, and Kihara-Hunt, Ai

Published
2024

35. 5 Missing the Mark in PSEA

Author

Dolan-Evans, Elliot, Westendorf, Jasmine-Kim, Jennings, Kathleen M, Mazurana, Dyan, Donnelly, Phoebe, Nyambeki, Leah, Kemp, Ellie, Martin, Sarah, Potts, Alina, White, Sabrina, Connors, Jane, Elderfield, Emily, Bian, Junru, Daigle, Megan, Nasser-Eddin, Nof, Abu-Assab, Nour, Naik, Asmita, Myrttinen, Henri, and Kihara-Hunt, Ai

Published
2024

36. 3 Victims' Rights and Remedial Action

Author

Dolan-Evans, Elliot, Westendorf, Jasmine-Kim, Jennings, Kathleen M, Mazurana, Dyan, Donnelly, Phoebe, Nyambeki, Leah, Kemp, Ellie, Martin, Sarah, Potts, Alina, White, Sabrina, Connors, Jane, Elderfield, Emily, Bian, Junru, Daigle, Megan, Nasser-Eddin, Nof, Abu-Assab, Nour, Naik, Asmita, Myrttinen, Henri, and Kihara-Hunt, Ai

Published
2024

37. Part I Where We've Been

Author

Dolan-Evans, Elliot, Westendorf, Jasmine-Kim, Jennings, Kathleen M, Mazurana, Dyan, Donnelly, Phoebe, Nyambeki, Leah, Kemp, Ellie, Martin, Sarah, Potts, Alina, White, Sabrina, Connors, Jane, Elderfield, Emily, Bian, Junru, Daigle, Megan, Nasser-Eddin, Nof, Abu-Assab, Nour, Naik, Asmita, Myrttinen, Henri, and Kihara-Hunt, Ai

Published
2024

38. 2 United Nations Police as a Double-Edged Sword for SEA Accountability

Author

Dolan-Evans, Elliot, Westendorf, Jasmine-Kim, Jennings, Kathleen M, Mazurana, Dyan, Donnelly, Phoebe, Nyambeki, Leah, Kemp, Ellie, Martin, Sarah, Potts, Alina, White, Sabrina, Connors, Jane, Elderfield, Emily, Bian, Junru, Daigle, Megan, Nasser-Eddin, Nof, Abu-Assab, Nour, Naik, Asmita, Myrttinen, Henri, and Kihara-Hunt, Ai

Published
2024

39. Part II How It's Going

Author

Dolan-Evans, Elliot, Westendorf, Jasmine-Kim, Jennings, Kathleen M, Mazurana, Dyan, Donnelly, Phoebe, Nyambeki, Leah, Kemp, Ellie, Martin, Sarah, Potts, Alina, White, Sabrina, Connors, Jane, Elderfield, Emily, Bian, Junru, Daigle, Megan, Nasser-Eddin, Nof, Abu-Assab, Nour, Naik, Asmita, Myrttinen, Henri, and Kihara-Hunt, Ai

Published
2024

40. 1 Reflections on 20-Plus Years of Protection from SEA Work

Author

Dolan-Evans, Elliot, Westendorf, Jasmine-Kim, Jennings, Kathleen M, Mazurana, Dyan, Donnelly, Phoebe, Nyambeki, Leah, Kemp, Ellie, Martin, Sarah, Potts, Alina, White, Sabrina, Connors, Jane, Elderfield, Emily, Bian, Junru, Daigle, Megan, Nasser-Eddin, Nof, Abu-Assab, Nour, Naik, Asmita, Myrttinen, Henri, and Kihara-Hunt, Ai

Published
2024

41. Acknowledgements

Author

Dolan-Evans, Elliot, Westendorf, Jasmine-Kim, Jennings, Kathleen M, Mazurana, Dyan, Donnelly, Phoebe, Nyambeki, Leah, Kemp, Ellie, Martin, Sarah, Potts, Alina, White, Sabrina, Connors, Jane, Elderfield, Emily, Bian, Junru, Daigle, Megan, Nasser-Eddin, Nof, Abu-Assab, Nour, Naik, Asmita, Myrttinen, Henri, and Kihara-Hunt, Ai

Published
2024

43. List of Figures and Tables

Author

Dolan-Evans, Elliot, Westendorf, Jasmine-Kim, Jennings, Kathleen M, Mazurana, Dyan, Donnelly, Phoebe, Nyambeki, Leah, Kemp, Ellie, Martin, Sarah, Potts, Alina, White, Sabrina, Connors, Jane, Elderfield, Emily, Bian, Junru, Daigle, Megan, Nasser-Eddin, Nof, Abu-Assab, Nour, Naik, Asmita, Myrttinen, Henri, and Kihara-Hunt, Ai

Published
2024

44. List of Abbreviations

Author

Dolan-Evans, Elliot, Westendorf, Jasmine-Kim, Jennings, Kathleen M, Mazurana, Dyan, Donnelly, Phoebe, Nyambeki, Leah, Kemp, Ellie, Martin, Sarah, Potts, Alina, White, Sabrina, Connors, Jane, Elderfield, Emily, Bian, Junru, Daigle, Megan, Nasser-Eddin, Nof, Abu-Assab, Nour, Naik, Asmita, Myrttinen, Henri, and Kihara-Hunt, Ai

Published
2024

45. Notes on Contributors

Author

Dolan-Evans, Elliot, Westendorf, Jasmine-Kim, Jennings, Kathleen M, Mazurana, Dyan, Donnelly, Phoebe, Nyambeki, Leah, Kemp, Ellie, Martin, Sarah, Potts, Alina, White, Sabrina, Connors, Jane, Elderfield, Emily, Bian, Junru, Daigle, Megan, Nasser-Eddin, Nof, Abu-Assab, Nour, Naik, Asmita, Myrttinen, Henri, and Kihara-Hunt, Ai

Published
2024

46. Table of Contents

Author

Dolan-Evans, Elliot, Westendorf, Jasmine-Kim, Jennings, Kathleen M, Mazurana, Dyan, Donnelly, Phoebe, Nyambeki, Leah, Kemp, Ellie, Martin, Sarah, Potts, Alina, White, Sabrina, Connors, Jane, Elderfield, Emily, Bian, Junru, Daigle, Megan, Nasser-Eddin, Nof, Abu-Assab, Nour, Naik, Asmita, Myrttinen, Henri, and Kihara-Hunt, Ai

Published
2024

47. Front Matter

Author

Dolan-Evans, Elliot, Westendorf, Jasmine-Kim, Jennings, Kathleen M, Mazurana, Dyan, Donnelly, Phoebe, Nyambeki, Leah, Kemp, Ellie, Martin, Sarah, Potts, Alina, White, Sabrina, Connors, Jane, Elderfield, Emily, Bian, Junru, Daigle, Megan, Nasser-Eddin, Nof, Abu-Assab, Nour, Naik, Asmita, Myrttinen, Henri, and Kihara-Hunt, Ai

Published
2024

48. Front Cover

Author

Dolan-Evans, Elliot, Westendorf, Jasmine-Kim, Jennings, Kathleen M, Mazurana, Dyan, Donnelly, Phoebe, Nyambeki, Leah, Kemp, Ellie, Martin, Sarah, Potts, Alina, White, Sabrina, Connors, Jane, Elderfield, Emily, Bian, Junru, Daigle, Megan, Nasser-Eddin, Nof, Abu-Assab, Nour, Naik, Asmita, Myrttinen, Henri, and Kihara-Hunt, Ai

Published
2024

50. Author Correction: c-Rel orchestrates energy-dependent epithelial and macrophage reprogramming in fibrosis

Author

Leslie, J, Macia, MG, Luli, S, Worrell, JC, Reilly, WJ, Paish, HL, Knox, A, Barksby, BS, Gee, LM, Zaki, MYW, Collins, AL, Burgoyne, RA, Cameron, R, Bragg, C, Xu, X, Chung, GW, Brown, CDA, Blanchard, AD, Nanthakumar, CB, Karsdal, M, Robinson, SM, Manas, DM, Sen, G, French, J, White, SA, Murphy, S, Trost, M, Zakrzewski, JL, Klein, U, Schwabe, RF, Mederacke, I, Nixon, C, Bird, T, Teuwen, L-A, Schoonjans, L, Carmeliet, P, Mann, J, Fisher, AJ, Sheerin, NS, Borthwick, LA, Mann, DA, and Oakley, F

Abstract

Correction to: Nature Metabolism https://doi.org/10.1038/s42255-020-00306-2, published online 9 November 2020. In the version of this article initially published, in the ×40 diseased human kidney images in Supplementary Fig. 1, the FSGS image duplicated the DN image. The error has been corrected in the HTML version of the article.

Published
2021

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