Search

Your search keyword '"Wesselman, Linda M.P."' showing total 30 results
Start Over Author "Wesselman, Linda M.P."
30 results on '"Wesselman, Linda M.P."'

4. Computer-assisted prediction of clinical progression in the earliest stages of AD

Author

Rhodius-Meester, Hanneke F.M., Liedes, Hilkka, Koikkalainen, Juha, Wolfsgruber, Steffen, Coll-Padros, Nina, Kornhuber, Johannes, Peters, Oliver, Jessen, Frank, Kleineidam, Luca, Molinuevo, José Luis, Rami, Lorena, Teunissen, Charlotte E., Barkhof, Frederik, Sikkes, Sietske A.M., Wesselman, Linda M.P., Slot, Rosalinde E.R., Verfaillie, Sander C.J., Scheltens, Philip, Tijms, Betty M., Lötjönen, Jyrki, and van der Flier, Wiesje M.

Published
2018
Full Text
View/download PDF

5. ATN classification and clinical progression in subjective cognitive decline: The SCIENCe project

Author

Ebenau, Jarith L., Timmers, Tessa, Wesselman, Linda M.P., Verberk, Inge M.W., Verfaillie, Sander C.J., Slot, Rosalinde E.R., van Harten, Argonde C., Teunissen, Charlotte E., Barkhof, Frederik, van den Bosch, Karlijn A., van Leeuwenstijn, Mardou, Tomassen, Jori, Braber, Anouk den, Visser, Pieter Jelle, Prins, Niels D., Sikkes, Sietske A.M., Scheltens, Philip, van Berckel, Bart N.M., and van der Flier, Wiesje M.

Published
2020
Full Text
View/download PDF

6. Serum glial fibrillary acidic protein and neurofilament light as prognostic biomarkers for clinical progression in subjective cognitive decline: The SCIENCe project

Author

Verberk, Inge M.W., primary, Laarhuis, Malika B, additional, van den Bosch, Karlijn A., additional, Ebenau, Jarith L., additional, Leeuwenstijn, Mardou, additional, Wesselman, Linda M.P., additional, Prins, Niels D., additional, Scheltens, Philip, additional, Teunissen, Charlotte E., additional, and van Der Flier, Wiesje, additional

Published
2020
Full Text
View/download PDF

7. Grey zone amyloid burden heralds future memory decline: The SCIENCe Project

Author

Ebenau, Jarith L., primary, Verfaillie, Sander C.J., additional, van den Bosch, Karlijn A., additional, Timmers, Tessa, additional, Wesselman, Linda M.P., additional, van Leeuwenstijn, Mardou, additional, Barkhof, Frederik, additional, Prins, Niels D., additional, Scheltens, Philip, additional, van Der Flier, Wiesje, additional, and Van Berckel, Bart N.M., additional

Published
2020
Full Text
View/download PDF

8. A suboptimal diet is associated with poorer cognition: The NUDAD project

Author

Fieldhouse, Jay L.P., Doorduijn, Astrid S., de Leeuw, Francisca A., Verhaar, Barbara J.H., Koene, Ted, Wesselman, Linda M.P., de van der Schueren, Marian, Visser, Marjolein, van de Rest, Ondine, Scheltens, Philip, Kester, Maartje I., van der Flier, Wiesje M., Fieldhouse, Jay L.P., Doorduijn, Astrid S., de Leeuw, Francisca A., Verhaar, Barbara J.H., Koene, Ted, Wesselman, Linda M.P., de van der Schueren, Marian, Visser, Marjolein, van de Rest, Ondine, Scheltens, Philip, Kester, Maartje I., and van der Flier, Wiesje M.

Abstract

Nutrition is one of the modifiable risk factors for cognitive decline and Alzheimer’s disease (AD) dementia, and is therefore highly relevant in the context of prevention. However, knowledge of dietary quality in clinical populations on the spectrum of AD dementia is lacking, therefore we studied the association between dietary quality and cognitive impairment in Alzheimer’s disease (AD) dementia, mild cognitive impairment (MCI) and controls. We included 357 participants from the NUDAD project (134 AD dementia, 90 MCI, 133 controls). We assessed adherence to dietary guidelines (components: vegetables, fruit, fibers, fish, saturated fat, trans‐fat, salt, and alcohol), and cognitive performance (domains: memory, language, visuospatial functioning, attention, and executive functioning). In the total population, linear regression analyses showed a lower vegetable intake is associated with poorer global cognition, visuospatial functioning, attention and executive functioning. In AD dementia, lower total adherence to dietary guidelines and higher alcohol intake were associated with poorer memory, a lower vegetable intake with poorer global cognition and executive functioning, and a higher trans‐fat intake with poorer executive functioning. In conclusion, a suboptimal diet is associated with more severely impaired cognition—this association is mostly attributable to a lower vegetable intake and is most pronounced in AD dementia.

Published
2020

9. F1‐04‐03: ATN BIOMARKER MODEL AS A DETERMINANT OF COGNITIVE DECLINE AND INCIDENT CLINICAL PROGRESSION IN SUBJECTIVE COGNITIVE DECLINE: THE SCIENCE PROJECT

Author

Ebenau, Jarith, primary, Timmers, Tessa, additional, Wesselman, Linda M.P., additional, Verberk, Inge M.W., additional, Verfaillie, Sander C.J., additional, Slot, Rosalinde E.R., additional, Teunissen, Charlotte E., additional, Barkhof, Frederik, additional, van den Bosch, Karlijn, additional, van Leeuwenstijn, Mardou, additional, Prins, Niels D., additional, Sikkes, Sietske A.M., additional, Scheltens, Philip, additional, Van Berckel, Bart N.M., additional, and van der Flier, Wiesje M., additional

Published
2019
Full Text
View/download PDF

10. Dietary Patterns Are Related to Clinical Characteristics in Memory Clinic Patients with Subjective Cognitive Decline: The SCIENCe Project

Author

Wesselman, Linda M.P., Doorduijn, Astrid S., Leeuw, Francisca A., de, Verfaillie, Sander C.J., Leeuwenstijn-Koopman, Mardou, van, Slot, Rosalinde E.R., Kester, Maartje I., Prins, Niels D., Rest, Ondine, van de, Schueren, Marian A.E., van der, Scheltens, Philip, Sikkes, Sietske A.M., Flier, Wiesje M., van der, Wesselman, Linda M.P., Doorduijn, Astrid S., Leeuw, Francisca A., de, Verfaillie, Sander C.J., Leeuwenstijn-Koopman, Mardou, van, Slot, Rosalinde E.R., Kester, Maartje I., Prins, Niels D., Rest, Ondine, van de, Schueren, Marian A.E., van der, Scheltens, Philip, Sikkes, Sietske A.M., and Flier, Wiesje M., van der

Abstract

As nutrition is one of the modifiable risk factors for cognitive decline, we studied the relationship between dietary quality and clinical characteristics in cognitively normal individuals with subjective cognitive decline (SCD). We included 165 SCD subjects (age: 64 ± 8 years; 45% female) from the SCIENCe project, a prospective memory clinic based cohort study on SCD. The Dutch Healthy Diet Food Frequency Questionnaire (DHD-FFQ) was used to assess adherence to Dutch guidelines on vegetable, fruit, fibers, fish, saturated fat, trans fatty acids, salt and alcohol intake (item score 0-10, higher score indicating better adherence). We measured global cognition (Mini Mental State Examination), cognitive complaints (Cognitive Change Index self-report; CCI) and depressive symptoms (Center for Epidemiologic Studies Depression Scale; CES-D). Using principal component analysis, we identified dietary components and investigated their relation to clinical characteristics using linear regression models adjusted for age, sex and education. We identified three dietary patterns: (i) "low-Fat-low-Salt", (ii) "high-Veggy", and (iii) "low-Alcohol-low-Fish". Individuals with lower adherence on "low-Fat-low-Salt" had more depressive symptoms (β -0.18 (-2.27--0.16)). Higher adherence to "high-Veggy" was associated with higher MMSE scores (β 0.30 (0.21-0.64)). No associations were found with the low-Alcohol-low-Fish component. We showed that in SCD subjects, dietary quality was related to clinically relevant outcomes. These findings could be useful to identify individuals that might benefit most from nutritional prevention strategies to optimize brain health.

Published
2019

12. Toward a theory‐based specification of non‐pharmacological treatments in aging and dementia: Focused reviews and methodological recommendations.

Author

Sikkes, Sietske A.M., Tang, Yi, Jutten, Roos J., Wesselman, Linda M.P., Turkstra, Lyn S., Brodaty, Henry, Clare, Linda, Cassidy‐Eagle, Erin, Cox, Kay L., Chételat, Gaël, Dautricourt, Sophie, Dhana, Klodian, Dodge, Hiroko, Dröes, Rose‐Marie, Hampstead, Benjamin M., Holland, Thomas, Lampit, Amit, Laver, Kate, Lutz, Antoine, and Lautenschlager, Nicola T.

Abstract

Introduction: Non‐pharmacological treatments (NPTs) have the potential to improve meaningful outcomes for older people at risk of, or living with dementia, but research often lacks methodological rigor and continues to produce mixed results. Methods: In the current position paper, experts in NPT research have specified treatment targets, aims, and ingredients using an umbrella framework, the Rehabilitation Treatment Specification System. Results: Experts provided a snapshot and an authoritative summary of the evidence for different NPTs based on the best synthesis efforts, identified main gaps in knowledge and relevant barriers, and provided directions for future research. Experts in trial methodology provide best practice principles and recommendations for those working in this area, underscoring the importance of prespecified protocols. Discussion: We conclude that the evidence strongly supports various NPTs in relation to their primary targets, and discuss opportunities and challenges associated with a unifying theoretical framework to guide future efforts in this area. [ABSTRACT FROM AUTHOR]

Published
2021
Full Text
View/download PDF

13. O2‐06‐03: AMYLOID‐β LOAD IS RELATED TO WORRIES IN INDIVIDUALS WITH SUBJECTIVE COGNITIVE DECLINE

Author

Verfaillie, Sander C.J., primary, Timmers, Tessa, additional, Slot, Rosalinde E.R., additional, van der Weijden, Chris W.J., additional, Wesselman, Linda M.P., additional, Prins, Niels D., additional, Sikkes, Sietske A.M., additional, Lammertsma, Adriaan A., additional, Scheltens, Philip, additional, Ossenkoppele, Rik, additional, van Berckel, Bart N.M., additional, and Van der Flier, Wiesje M., additional

Published
2018
Full Text
View/download PDF

14. IC‐P‐111: [ 18 F]FLORBETAPIR‐SPECIFIC BINDING IN RELATION TO COGNITION IN SUBJECTIVE COGNITIVE DECLINE

Author

Timmers, Tessa, primary, Ossenkoppele, Rik, additional, Verfaillie, Sander C.J., additional, Wesselman, Linda M.P., additional, Slot, Rosalinde E.R., additional, Prins, Niels D., additional, van der Weijden, Chris W.J., additional, Yaqub, Maqsood M., additional, Lammertsma, Adriaan A., additional, Boellaard, Ronald, additional, Van der Flier, Wiesje M., additional, and van Berckel, Bart N.M., additional

Published
2018
Full Text
View/download PDF

17. O2‐06‐01: [ 18 F]FLORBETAPIR SPECIFIC BINDING IN RELATION TO COGNITION IN SUBJECTIVE COGNITIVE DECLINE

Author

Timmers, Tessa, primary, Ossenkoppele, Rik, additional, Verfaillie, Sander C.J., additional, Wesselman, Linda M.P., additional, Slot, Rosalinde E.R., additional, Prins, Niels D., additional, van der Weijden, Chris W.J., additional, Yaqub, Maqsood M., additional, Lammertsma, Adriaan A., additional, Boellaard, Ronald, additional, Van der Flier, Wiesje M., additional, and van Berckel, Bart N.M., additional

Published
2018
Full Text
View/download PDF

18. P3‐289: HARMONIZATION OF SCD OPERATIONALIZATION ACROSS DIFFERENT MEMORY CLINIC SETTINGS: THE EURO‐SCD STUDY

Author

Jessen, Frank, primary, Wolfsgruber, Steffen, additional, Daamen, Marcel, additional, Molinuevo, José Luis, additional, Teunissen, Charlotte E., additional, Rami, Lorena, additional, Coll-Padros, Nina, additional, Bouwman, Femke H., additional, Slot, Rosalinde E.R., additional, Sikkes, Sietske A.M., additional, Wesselman, Linda M.P., additional, Peters, Oliver, additional, Buerger, Katharina, additional, Priller, Josef, additional, Laske, Christoph, additional, Teipel, Stefan J., additional, Spottke, Annika, additional, Heneka, Michael T., additional, Düzel, Emrah, additional, Drzezga, Alexander, additional, Boecker, Henning, additional, Van der Flier, Wiesje M., additional, and Wagner, Michael, additional

Published
2018
Full Text
View/download PDF

19. [P4-219]: [18 F]AV1451 BINDING POTENTIAL IN RELATION TO AMYLOID STATUS AND COGNITION IN SUBJECTS WITH SUBJECTIVE COGNITIVE DECLINE

Author

Timmers, Tessa, primary, Wolters, Emma E., additional, Ossenkoppele, Rik, additional, Verfaillie, Sander C.J., additional, van der Weijden, Chris W.J., additional, Golla, Sandeep S.V., additional, Slot, Rosalinde E.R., additional, Wesselman, Linda M.P., additional, Overbeek, Jose M., additional, Schmidt, Mark E., additional, Yaqub, Maqsood M., additional, Lammertsma, Adriaan A., additional, Scheltens, Philip, additional, van der Flier, Wiesje M., additional, and van Berckel, Bart N.M., additional

Published
2017
Full Text
View/download PDF

20. [18F]AV1451 BINDING POTENTIAL IN RELATION TO AMYLOID STATUS AND COGNITION IN SUBJECTS WITH SUBJECTIVE COGNITIVE DECLINE

Author

Timmers, Tessa, primary, Wolters, Emma E., additional, Ossenkoppele, Rik, additional, Verfaillie, Sander C.J., additional, van der Weijden, Chris W.J., additional, Golla, Sandeep S.V., additional, Slot, Rosalinde E.R., additional, Wesselman, Linda M.P., additional, Overbeek, Jose M., additional, Schmidt, Mark E., additional, Yaqub, Maqsood M., additional, Lammertsma, Adriaan A., additional, Scheltens, Philip, additional, van der Flier, Wiesje M., additional, and van Berckel, Bart N.M., additional

Published
2017
Full Text
View/download PDF

21. PROGNOSIS OF CLINICAL PROGRESSION IN SUBJECTIVE COGNITIVE DECLINE USING A CLINICAL DECISION SUPPORT SYSTEM

Author

Rhodius-Meester, Hanneke F.M., primary, Liedes, Hilkka, additional, Wolfsgruber, Steffen, additional, Coll-Padros, Nina, additional, Koikkalainen, Juha, additional, Kornhuber, Johannes, additional, Peters, Oliver, additional, Jessen, Frank, additional, Kleineidam, Luca, additional, Molinuevo, José Luis, additional, Rami, Lorena, additional, Teunissen, Charlotte E., additional, Barkhof, Frederik, additional, Sikkes, Sietske A.M., additional, Wesselman, Linda M.P., additional, Slot, Rosalinde E.R., additional, Scheltens, Philip, additional, Tijms, Betty M., additional, Lotjonen, Jyrki, additional, and van der Flier, Wiesje M., additional

Published
2017
Full Text
View/download PDF

22. CHARACTERIZING INDIVIDUALS WITH SUBJECTIVE COGNITIVE DECLINE: THE SUBJECTIVE COGNITIVE IMPAIRMENT COHORT (SCIENCE)

Author

Slot, Rosalinde E.R., primary, Verfaillie, Sander C.J., additional, Overbeek, Jose M., additional, Timmers, Tessa, additional, Wesselman, Linda M.P., additional, Bouwman, Femke H., additional, Prins, Niels D., additional, Teunissen, Charlotte E., additional, Dols, Annemieke, additional, Barkhof, Frederik, additional, van Berckel, Bart N.M., additional, Scheltens, Philip, additional, Sikkes, Sietske A.M., additional, and van der Flier, Wiesje M., additional

Published
2017
Full Text
View/download PDF

23. [P3-566]: IMPROVING BRAIN HEALTH THROUGH AN ONLINE LIFESTYLE PROGRAM: PREFERENCES OF INDIVIDUALS WITH SUBJECTIVE COGNITIVE DECLINE

Author

Wesselman, Linda M.P., primary, Schild, Ann-Katrin, additional, Coll-Padros, Nina, additional, van der Borg, Wieke, additional, Slot, Rosalinde E.R., additional, Sannemann, Lena, additional, Rami, Lorena, additional, Molinuevo, José Luis, additional, Bouwman, Femke H., additional, Jessen, Frank, additional, van der Flier, Wiesje M., additional, and Sikkes, Sietske A.M., additional

Published
2017
Full Text
View/download PDF

24. IMPROVING BRAIN HEALTH THROUGH AN ONLINE LIFESTYLE PROGRAM: PREFERENCES OF INDIVIDUALS WITH SUBJECTIVE COGNITIVE DECLINE

Author

Wesselman, Linda M.P., primary, Schild, Ann-Katrin, additional, Coll-Padros, Nina, additional, van der Borg, Wieke, additional, Slot, Rosalinde E.R., additional, Sannemann, Lena, additional, Rami, Lorena, additional, Molinuevo, José Luis, additional, Bouwman, Femke H., additional, Jessen, Frank, additional, van der Flier, Wiesje M., additional, and Sikkes, Sietske A.M., additional

Published
2017
Full Text
View/download PDF

25. ATN BIOMARKER MODEL AS A DETERMINANT OF COGNITIVE DECLINE AND INCIDENT CLINICAL PROGRESSION IN SUBJECTIVE COGNITIVE DECLINE: THE SCIENCE PROJECT

Author

Ebenau, Jarith, Timmers, Tessa, Wesselman, Linda M.P., Verberk, Inge M.W., Verfaillie, Sander C.J., Slot, Rosalinde E.R., Teunissen, Charlotte E., Barkhof, Frederik, van den Bosch, Karlijn, van Leeuwenstijn, Mardou, Prins, Niels D., Sikkes, Sietske A.M., Scheltens, Philip, Van Berckel, Bart N.M., and van der Flier, Wiesje M.

Published
2019
Full Text
View/download PDF

29. HARMONIZATION OF SCD OPERATIONALIZATION ACROSS DIFFERENT MEMORY CLINIC SETTINGS: THE EURO-SCD STUDY

Author

Jessen, Frank, Wolfsgruber, Steffen, Daamen, Marcel, Molinuevo, José Luis, Teunissen, Charlotte E., Rami, Lorena, Coll-Padros, Nina, Bouwman, Femke H., Slot, Rosalinde E.R., Sikkes, Sietske A.M., Wesselman, Linda M.P., Peters, Oliver, Buerger, Katharina, Priller, Josef, Laske, Christoph, Teipel, Stefan J., Spottke, Annika, Heneka, Michael T., Düzel, Emrah, Drzezga, Alexander, Boecker, Henning, Van der Flier, Wiesje M., and Wagner, Michael

Published
2018
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results