15,754 results on '"Wess, J."'
Search Results
2. The Standard Model on Non-Commutative Space-Time
- Author
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Calmet, X., Jurco, B., Schupp, P., Wess, J., and Wohlgenannt, M.
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High Energy Physics - Phenomenology ,High Energy Physics - Theory - Abstract
We consider the Standard Model on a non-commutative space and expand the action in the non-commutativity parameter theta. No new particles are introduced, the structure group is SU(3) x SU(2) x U(1). We derive the leading order action. At zeroth order the action coincides with the ordinary Standard Model. At leading order in theta we find new vertices which are absent in the Standard Model on commutative space-time. The most striking features are couplings between quarks, gluons and electroweak bosons and many new vertices in the charged and neutral currents. We find that parity is violated in non-commutative QCD. The Higgs mechanism can be applied. QED is not deformed in the minimal version of the NCSM to the order considered., Comment: 28 pages, v3: typos corrected, new appendix on alternative kinetic terms for gauge bosons; v4: typos corrected
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- 2001
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3. Supersymmetric Model with Grassmann-odd Lagrangian
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Soroka, D. V., Soroka, V. A., and Wess, J.
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High Energy Physics - Theory - Abstract
A supersymmetric $D = 1, N =1$ model with a Grassmann-odd Lagrangian is proposed which, in contrast to the model with an even Lagrangian, contains not only a kinetic term but also an interaction term for the coordinates entering into one real scalar Grassmann-even (bosonic) superfield., Comment: 6 pages, LATEX 2e. The talk given at the International Conference "Supersymmetries and Quantum Field Theory" (SSQFT'2000, NSC KIPT, Kharkov, Ukraine, 25-29 July, 2000). To be published in the Proceedings of this Conference. Corrections of misprints
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- 2001
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4. Structure of the Three-dimensional Quantum Euclidean Space
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Cerchiai, B. L., Madore, J., Schraml, S., and Wess, J.
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Mathematics - Quantum Algebra ,High Energy Physics - Theory ,Mathematical Physics ,81R50 ,17B37 - Abstract
As an example of a noncommutative space we discuss the quantum 3-dimensional Euclidean space $R^3_q$ together with its symmetry structure in great detail. The algebraic structure and the representation theory are clarified and discrete spectra for the coordinates are found. The q-deformed Legendre functions play a special role. A completeness relation is derived for these functions., Comment: 22 pages, latex
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- 2000
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5. q-Deformed Heisenberg Algebras
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Wess, J.
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Mathematical Physics ,High Energy Physics - Theory ,Mathematics - Quantum Algebra - Abstract
This lecture consists of two sections. In section 1 we consider the simplest version of a q-deformed Heisenberg algebra as an example of a noncommutative structure. We first derive a calculus entirely based on the algebra and then formulate laws of physics based on this calculus. Then we realize that an interpretation of these laws is only possible if we study representations of the algebra and adopt the quantum mechanical scheme. It turns out that observables like position or momentum have discrete eigenvalues and thus space gets a lattice-like structure. In section 2 we study a framework for higher dimensional noncommutative spaces based on quantum groups. The Poincare-Birkhoff-Witt property and conjugation properties play an essential role there. In these spaces derivatives are introduced and based on these derivatives a q-deformed Heisenberg algebra can be constructed., Comment: 63 pages, 2 figures, 38. Internationale Universitaetswochen fuer Kern- und Teilchenphysik, Schladming, Austria
- Published
- 1999
6. A Calculus Based on a q-deformed Heisenberg Algebra
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Cerchiai, B. L., Hinterding, R., Madore, J., and Wess, J.
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Mathematics - Quantum Algebra ,High Energy Physics - Theory ,81R50 ,17B37 - Abstract
We show how one can construct a differential calculus over an algebra where position variables x and momentum variables p have be defined. As the simplest example we consider the one-dimensional q-deformed Heisenberg algebra. This algebra has a subalgebra generated by x and its inverse which we call the coordinate algebra. A physical field is considered to be an element of the completion of this algebra. We can construct a derivative which leaves invariant the coordinate algebra and so takes physical fields into physical fields. A generalized Leibniz rule for this algebra can be found. Based on this derivative differential forms and an exterior differential calculus can be constructed., Comment: latex-file, 23 pages
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- 1998
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7. The Geometry of a $q$-Deformed Phase Space
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Cerchiai, B. L., Hinterding, R., Madore, J., and Wess, J.
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Mathematics - Quantum Algebra ,High Energy Physics - Theory ,81R50 ,17B37 - Abstract
The geometry of the $q$-deformed line is studied. A real differential calculus is introduced and the associated algebra of forms represented on a Hilbert space. It is found that there is a natural metric with an associated linear connection which is of zero curvature. The metric, which is formally defined in terms of differential forms, is in this simple case identifiable as an observable., Comment: latex file, 26 pp, a typing error corrected
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- 1998
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8. q-Deformed Minkowski Space based on a q-Lorentz Algebra
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Cerchiai, B. L. and Wess, J.
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Mathematics - Quantum Algebra ,High Energy Physics - Theory ,81R50 ,17B37 - Abstract
The Hilbert space representations of a non-commutative q-deformed Minkowski space, its momenta and its Lorentz boosts are constructed. The spectrum of the diagonalizable space elements shows a lattice-like structure with accumulation points on the light-cone., Comment: 31 pages, 1 figure
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- 1998
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9. Non-commutative Euclidean and Minkowski Structure
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Lorek, A., Weich, W., and Wess, J.
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Mathematics - Quantum Algebra - Abstract
A noncommutative *-algebra that generalizes the canonical commutation relations and that is covariant under the quantum groups SOq(3) or SOq(1,3) is introduced. The generating elements of this algebra are hermitean and can be identified with coordinates, momenta and angular momenta. In addition a unitary scaling operator is part of the algebra., Comment: 36 pages, amstex
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- 1997
10. Quantum groups and q-lattices in phase space
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Wess, J.
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Mathematics - Quantum Algebra - Abstract
Quantum groups lead to an algebraic structure that can be realized on quantum spaces. These are noncommutative spaces that inherit a well defined mathematical structure from the quantum group symmetry. In turn such quantum spaces can be interpreted as noncommutative configuration spaces for physical systems which carry a symmetry like structure. These configuration spaces will be generalized to noncommutative phase space. The definition of the noncommutative phase space will be based on a differential calculus on the configuration space which is compatible with the symmetry. In addition a conjugation operation will be defined which will allow us to define the phase space variables in terms of algebraically selfadjoint operators. An interesting property of the phase space observables will be that they will have a discrete spectrum. These noncommutative phase space puts physics on a lattice structure., Comment: 6 pages, Postscript
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- 1996
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11. A q-Deformation of the Harmonic Oscillator
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Lorek, A., Ruffing, A., and Wess, J.
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High Energy Physics - Theory ,Mathematics - Quantum Algebra - Abstract
The q-deformed harmonic oscillator is studied in the light of q-deformed phase space variables. This allows a formulation of the corresponding Hamiltonian in terms of the ordinary canonical variables $x$ and $p$. The spectrum shows unexpected features such as degeneracy and an additional part that cannot be reached from the ground state by creation operators. The eigenfunctions show lattice structure, as expected., Comment: 19 pages, latex, no figures
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- 1996
12. q-deformed Phase Space and its Lattice Structure
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Fichtmueller, M., Lorek, A., and Wess, J.
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High Energy Physics - Theory - Abstract
A q-deformed two-dimensional phase space is studied as a model for a noncommutative phase space. A lattice structure arises that can be interpreted as a spontaneous breaking of a continuous symmetry. The eigenfunctions of a Hamiltonian that lives on such a lattice are derived as wavefunctions in ordinary $x$-space., Comment: 11 pages, latex, no figures
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- 1995
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13. Dynamical Symmetries in q-deformed Quantum Mechanics
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Lorek, A. and Wess, J.
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Mathematics - Quantum Algebra ,High Energy Physics - Theory - Abstract
The dynamical algebra of the q-deformed harmonic oscillator is constructed. As a result, we find the free deformed Hamiltonian as well as the Hamiltonian of the deformed oscillator as a complicated, momentum dependent interaction Hamiltonian in terms of the usual canonical variables. Furthermore we construct a well-defined algebra SU$_q$(1,1) with consistent conjugation properties and comultiplication. We obtain non lowest weight representations of this algebra., Comment: 19 pages, latex, no figures
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- 1995
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14. A calculus based on a
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Cerchiai, BL, Hinterding, R, Madore, J, and Wess, J
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math.QA ,hep-th ,81R50 ,17B37 ,Atomic ,Molecular ,Nuclear ,Particle and Plasma Physics ,Quantum Physics ,Nuclear & Particles Physics - Abstract
We show how one can construct a differential calculus over an algebra where position variables cursive Greek chi and momentum variables p have be defined. As the simplest example we consider the one-dimensional q-deformed Heisenberg algebra. This algebra has a subalgebra generated by cursive Greek chi and its inverse which we call the coordinate algebra. A physical field is considered to be an element of the completion of this algebra. We can construct a derivative which leaves invariant the coordinate algebra and so takes physical fields into physical fields. A generalized Leibniz rule for this algebra can be found. Based on this derivative differential forms and an exterior differential calculus can be constructed.
- Published
- 1999
15. Gauge Theories on Noncommutative Spacetime Treated by the Seiberg-Witten Method*
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Wess, J., Beig, R., editor, Beiglböck, W., editor, Domcke, W., editor, Englert, B.-G., editor, Frisch, U., editor, Hänggi, P., editor, Hasinger, G., editor, Hepp, K., editor, Hillebrandt, W., editor, Imboden, D., editor, Jaffe, R. L., editor, Lipowsky, R., editor, Löhneysen, H. v., editor, Ojima, I., editor, Sornette, D., editor, Theisen, S., editor, Weise, W., editor, Wess, J., editor, Zittartz, J., editor, Carow-Watamura, Ursula, editor, Maeda, Yoshiaki, editor, and Watamura, Satoshi, editor
- Published
- 2005
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16. q-Deformed Poincaré Algebra
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Ogievetsky, O, Schmidke, W B, Wess, J, and Zumino, B
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- 1991
17. q-Deformed Minkowski Algebra and Its Space-Time Lattice
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Wess, J., Beig, R., editor, Ehlers, J., editor, Frisch, U., editor, Hepp, K., editor, Jaffe, R. L., editor, Kippenhahn, R., editor, Ojima, I., editor, Weidenmüller, H. A., editor, Wess, J., editor, Zittartz, J., editor, Beiglböck, W., editor, Borowiec, Andrzej, editor, Cegła, Wojciech, editor, Jancewicz, Bernard, editor, and Karwowski, Witold, editor
- Published
- 2000
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18. q-Deformed heisenberg algebra
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Wess, J., Araki, H., editor, Beig, R., editor, Ehlers, J., editor, Frisch, U., editor, Hepp, K., editor, Jaffe, R. L., editor, Kippenhahn, R., editor, Weidenmüller, H. A., editor, Wess, J., editor, Zittartz, J., editor, Beiglböck, W., editor, Lehr, Sabine, editor, Wess, Julius, editor, and Akulov, Vladimir P., editor
- Published
- 1998
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19. Muscarinic Acetylcholine Receptor Knockout Mice
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Wess, J., Zhang, W., Duttaroy, A., Miyakawa, T., Gomeza, J., Cui, Y., Basile, A. S., Bymaster, F. P., McKinzie, D. L., Felder, C. C., Deng, C., Yamada, M., Starke, K., editor, Offermanns, Stefan, editor, and Hein, Lutz, editor
- Published
- 2004
- Full Text
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20. Adipocyte Gq signaling is a regulator of glucose and lipid homeostasis in mice.
- Author
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Kimura, T, Pydi, SP, Wang, L, Haspula, D, Cui, Y, Lu, H, König, GM, Kostenis, E, Steinberg, GR, Gavrilova, O, Wess, J, Kimura, T, Pydi, SP, Wang, L, Haspula, D, Cui, Y, Lu, H, König, GM, Kostenis, E, Steinberg, GR, Gavrilova, O, and Wess, J
- Abstract
Obesity is the major driver of the global epidemic in type 2 diabetes (T2D). In individuals with obesity, impaired insulin action leads to increased lipolysis in adipocytes, resulting in elevated plasma free fatty acid (FFA) levels that promote peripheral insulin resistance, a hallmark of T2D. Here we show, by using a combined genetic/biochemical/pharmacologic approach, that increased adipocyte lipolysis can be prevented by selective activation of adipocyte Gq signaling in vitro and in vivo (in mice). Activation of this pathway by a Gq-coupled designer receptor or by an agonist acting on an endogenous adipocyte Gq-coupled receptor (CysLT2 receptor) greatly improved glucose and lipid homeostasis in obese mice or in mice with adipocyte insulin receptor deficiency. Our findings identify adipocyte Gq signaling as an essential regulator of whole-body glucose and lipid homeostasis and should inform the development of novel classes of GPCR-based antidiabetic drugs.
- Published
- 2022
21. Conditional and selective activation of the Gq pathway in the heart and its impact on cardiac function in vivo: P028
- Author
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Kaiser, E., Wess, J., Tian, Q., Schröder, L., Kaestner, L., and Lipp, P.
- Published
- 2014
22. Vagal tone dominates autonomic control of mouse heart rate at thermoneutrality
- Author
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Swoap, S.J., Li, C., Wess, J., Parsons, A.D., Williams, T.D., and Overton, J.M.
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Heart beat -- Physiological aspects ,Heart beat -- Control ,Heart beat -- Research ,Nervous system, Sympathetic -- Physiological aspects ,Nervous system, Sympathetic -- Research ,Biological sciences - Abstract
It is generally accepted that cardiac sympathetic tone dominates the control of heart rate (HR) in mice. However, we have recently challenged this notion given that HR in the mouse is responsive to ambient temperature (Ta) and that the housing Ta is typically 2123[degrees]C, well below the thermoneutral zone ([approximately equal to]30[degrees]C) of this species. To specifically test the hypothesis that cardiac sympathetic tone is the primary mediator of HR control in the mouse, we first examined the metabolic and cardiovascular responses to rapid changes in Ta to demonstrate the sensitivity of the mouse cardiovascular system to Ta. We then determined HR in 1) mice deficient in cardiac sympathetic tone ('B-less' mice), 2) mice deficient in cardiac vagal tone [muscarinic M2 receptor ([M.sub.2][R.sup.-/-]) mice], and 3) littermate controls. At a [T.sub.a] of 30[degrees]C, the HR of [beta]-less mice was identical to that of wild-type mice (351 [+ or -] 11 and 363 [+ or -] 10 beats/min, respectively). However, the HR of [M.sub.2][R.sup.-/-] mice was significantly greater (416 [+ or -] 7 beats/min), demonstrating that vagal tone predominates over HR control at this Ta. When these mice were calorically restricted to 70% of normal intake, HR fell equally in wild-type, B-less, and [M.sub.2] [R.sup.-/-] mice (AHR = 73 [+ or -] 9, 76 [+ or -] 3, and 73 [+ or -] 7 beats/min, respectively), suggesting that the fall in intrinsic HR governs bradycardia of calorically restricted mice. Only when the [T.sub.a] was relatively cool, at 23[degrees]C, did [beta]-less mice exhibit a HR (442 [+ or -] 14 beats/rain) that was different from that of littermate controls (604 [+ or -] 10 beats/min) and [M.sub.2] [R.sup.-/-] mice (602 [+ or -] 5 beats/min). These experiments conclusively demonstrate that in the absence of cold stress, regulation of vagal tone and modulation of intrinsic rate are important determinants of HR control in the mouse. telemetry; intrinsic heart rate; cold stress; caloric restriction; sympathetic nervous system
- Published
- 2008
23. Poster abstracts
- Author
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Ferrie, J., Shipley, M., Cappuccio, F., Brunner, E., Miller, M., Kumari, M., Marmot, M., Coenen, A., Castillo, J. L., Araya, F., Bustamante, G., Montecino, L., Torres, C., Oporto, S., Gronli, J., Fiske, E., Murison, R., Bjorvatn, B., Sorensen, E., Ursin, R., Portas, C. M., Rajaraman, S., Gribok, A., Wesensten, N., Balkin, T., Reifman, J., Dursunoglu, N., Ozkurt, S., Baser, S., Delen, O., Sarikaya, S., Sadler, P., Mitchell, P., Françon, D., Decobert, M., Herve, B., Richard, A., Griebel, G., Avenet, P., Scatton, B., Fur, G. L., Eckert, D., Jordan, A., Wellman, A., Smith, S., Malhotra, A., White, D., Bruck, D., Thomas, I., Kritikos, A., Oertel, W., Stiasny-Kolster, K., Garcia-Borreguero, D., Poewe, W., Hoegl, B., Kohnen, R., Schollmayer, E., Keffel, J., Trenkwalder, C., Valle, A., Roizenblatt, S., Fregni, F., Boggio, P., Tufik, S., Ward, K., Robertson, L., Palmer, L., Eastwood, P., Hillman, D., Lee, J., Mukherjee, S., de Padova, V., Barbato, G., Ficca, G., Zilli, I., Salzarulo, P., Veldi, M., Hion, T., Vasar, V., Kull, M., Nowak, L., Davis, J., Latzer, Y., Tzischinsky, O., Crowley, S., Carskadon, M., Anca-Herschkovitsch, M., Frey, D., Ortega, J., Wiseman, C., Farley, C., Wright, K., Campbell, A., Neill, A., Spiegel, K., Leproult, R., Tasali, E., Scherberg, N., van Cauter, E., Noradina, A. T., Karim, N. A., Norlinah, I., Raymond, A. A., Sahathevan, R., Hamidon, B., Werth, E., Poryazova, R., Khatami, R., Bassetti, C., Beran, R. G., Ainley, L., Holand, G., Duncan, J., Kinney, H., Davis, B., Hood, B., Frey, S., Schmidt, C., Hofstetter, M., Peigneux, P., Cajochen, C., Hu, W.-P., Li, J.-D., Zhang, C., Boehmer, L., Siegel, J., Zhou, Q.-Y., Sagawa, Y., Kondo, H., Takemura, T., Kanayama, H., Kaneko, Y., Sato, M., Kanbayashi, T., Hishikawa, Y., Shimizu, T., Viola, A., James, L., Schlangen, L., Dijk, D.-J., Andretic, R., Kim, Y.-C., Han, K.-A., Jones, F., Greenspan, R., Sanford, L., Yang, L., Tang, X., Dieter, K., Uta, E., Sven, H., Richard, M., Oyane, N., Pallesen, S., Holsten, F., Inoue, Y., Fujita, M., Emura, N., Kuroda, K., Uchimura, N., Johnston, A., Astbury, J., Kennedy, G., Hoedlmoser, K., Schabus, M., Pecherstorfer, T., Moser, S., Gruber, G., Anderer, P., Klimesch, W., Naidoo, N., Ferber, M., Pack, A., Neu, D., Mairesse, O., Hoffmann, G., Dris, A., Lambrecht, L., Linkowski, P., Verbanck, P., Le Bon, O., Matsuura, N., Yamao, M., Adachi, N., Aritomi, R., Komada, Y., Tanaka, H., Shirakawa, S., Kondoh, H., Takemura, F., Ohnuma, S., Suzuki, M., Uemura, S., Iskra-Golec, I., Smith, L., Thanh, D.-V., Boly, M., Phillips, C., Steven, L., Luxen, A., Maquet, M., Jay, S., Dawson, D., Lamond, N., Basner, M., Fomberstein, K., Dinges, D., Ogawa, K., Nittono, H., Yamazaki, K., Hori, T., Glamann, C., Hornung, O., Hansen, M.-L, Danker-Hopfe, H., Jung, C., Kecklund, G., Anund, A., Peters, B., Åkerstedt, T., Verster, J., Roehrs, T., Mets, M., de Senerpont Domis, L., Olivier, B., Volkerts, E., Knutson, K., Lauderdale, D., Rathouz, P., Christie, M., Chen, L., Bolortuya, Y., Lee, E., Mckenna, J., Mccarley, R., Strecker, R., Tamaki, M., Matsuoka, T., Aritake, S., Suzuki, H., Kuriyama, K., Ozaki, A., Abe, Y., Enomoto, M., Tagaya, H., Mishima, K., Matsuura, M., Uchiyama, M., Lima-Pacheco, E., Davis, K., Sabourin, C., Lortie-Lussier, M., de Koninck, J., van Der Werf, Y., van Der Helm, E., Schoonheim, M., van Someren, E., Tokley, M., Ball, M., Sato, T., Ghilardi, M. F., Moisello, C., Bove, M., Busi, M., Pelosin, E., Tononi, G., Eguchi, N., Sakata, M., Urade, Y., Doe, N., Yoshihara, K., Abe, K., Manabe, Y., Iwatsuki, K., Hayashi, T., Shoji, M., Kamiya, T., Gooley, J., Brainard, G., Rajaratnam, S., Kronauer, R., Czeisler, C., Lockley, S., Phillips, A., Robinson, P., Burgess, H., Revell, V., Eastman, C., Bihari, S., Ramakrishnan, N., Camerino, D., Conway, P. M., Costa, G., Vandewalle, G., Albouy, G., Sterpenich, V., Darsaud, A., Rauchs, G., Berken, P.-Y, Balteau, E., Maquet, P., Tendero, J. A., Domenech, M. P., Isern, F. S., Martínez, C., Roure, N., Sancho, E. E., Moreno, C. R., Silva, M., Marqueze, E. C., Waage, S., Bobko, N., Chernyuk, V., Yavorskiy, Y., Saxvig, I., Sørensen, E., de Mello, M. T., Esteves, A., Teixeira, C., Bittencourt, L. R., Silva, R., Pires, M. L., Mottram, V., Middelton, B., Arendt, J., Amaral, O., Rodrigues, M., Pereira, C., Tavares, I., Baba, K., Honma, S., Honma, K.-I., Yamanaka, Y., Hashimoto, S., Tanahashi, Y., Nishide, S.-Y, Honma, K.-I, Sletten, T., Middleton, B., Lederle, K., Skene, D., Roth, T., Walsh, J., Hogben, A., Ellis, J., Archer, S., von Schantz, M., Chen, N.-H., Wang, P.-C., Chen, C.-W., Lin, Y., Shih, T.-S., Armstrong, S., Redman, J., Stephan, E., David, M., Delanaud, S., Chardon, K., Libert, J.-P., Bach, V., Telliez, F., Reid, K., Jaksa, A., Eisengart, J., Kane, P., Naylor, E., Zee, P., Viola, A. U., de Valck, E., Hofmans, J., Theuns, P., Cluydts, R., Alexander, G., Karel, M., Christina, R., Sohn, I.-K., Cho, I. H., Kim, S. J., Yu, S.-H., Kim, H., Yoo, S. Y., Koh, S.-H., Cho, S.-J., Rotenberg, L., Silva-Costa, A., Griep, R. H., Amely, T., Kennedy, G. A., Pavlis, A., Thompson, B., Pierce, R., Howard, M., Briellmann, R., Venkateswaran, S., Blunden, S., Krawczyk, E., Blake, J., Gururajan, R., Kerr, D., Matuisi, T., Iwasaki, M., Yamasita, N., Iemura, A., Ohya, T., Yanagawa, T., Misa, R., Coleman, G., Conduit, R., Duce, B., Hukins, C., Nyandaiti, Y. W., Bamaki, S., Mohammed, A., Kwajarfa, S., Veeramachaneni, S. P., Murthy, A., Wilson, A., Maul, J., Hall, G., Stick, S., Moseley, L., Gradisar, M., Kurihara, T., Yamamoto, M., Yamamoto, S., Kuranari, M., Sparks, C. B., Bartle, A., Beckert, L., Latham-Smith, F. B., Hilton, J., Whitehead, B., Gulliver, T., Salvini, A., Grahame, S., Swift, M., Laybutt, N., Sharon, D., Mack, C., Hymell, B., Perrine, B., Ideshita, K., Taira, M., Matuo, A., Furutani, M., van Dongen, H., Mott, C., Huang, J.-K., Mollicone, D. J., Mckenzie, F., Dinges, David, Barnes, M., Rochford, P., Churchward, T., O’Donoghue, F., Penzel, T., Fietze, I., Canisius, S., Bekiaris, E., Terrill, P. I., Wilson, S., Suresh, S., Cooper, D., Suzuki, T., Ouchi, K., Moriya, A., Kameyama, K., Takahashi, M., Büttner, A., Rühle, K.-H., Wang, D., Wong, K., Dungan, II, G., Grunstein, R., Davidson, P., Jones, R., Gergely, V., Mashima, K., Miyazaki, S., Tanaka, T., Okawa, M., Yamada, N., Wyner, A., Raizen, D., Galante, R., Ng, A. K., Koh, T. S., Lim, L. L., Puvanendran, K., Peiris, M., Bones, P., Roebuck, T., Ho, S., Szollosi, I., Naughton, M., Williams, G., Parsley, C., Harris, M.-A., Thornton, A., Ruehland, W., Banks, S., Arroyo, S., Carroll, K., Pilmore, J., Stewart, C., Hamilton, G., van Acker, F., Cvetkovic, D., Holland, G., Cosic, I., Tolson, J., Worsnop, C., Cresswell, P., Hart, I., Bouarab, M., Delechelle, E., Drouot, X., Acebo, C., Singh, P., Lakey, T., Schachter, L., Rand, J., Collin, H., Snyder, E., Ma, J., Svetnick, V., Deacon, S., Dana, B., Konstanze, D., Uwe, M., Ingo, F., Thomas, P., Ivar, R., Mackiewicz, M., Shockley, K., Romer, M., Zimmerman, J., Baldwin, D., Jensen, S., Churchill, G., Paigen, B., Imeri, L., Ferrari, L., Bianchi, S., Dossena, S., Garofoli, A., Mangieri, M., Tagliavini, F., Forloni, G., Chiesa, R., Pedrazzoli, M., Pereira, D., Veauny, M., Bodenmann, S., Hohoff, C., Freitag, C., Deckert, J., Rétey, J., Landolt, H.-P., Strohl, K., Price, E., Yamauchi, M., Dostal, J., Feng, P., Han, F., Havekes, R., Novati, A., Hagewoud, R., Barf, P., van Der Borght, K., van Der Zee, E., Meerlo, P., Ruby, P., Caclin, A., Boulet, S., Delpuech, C., Morlet, D., Veasey, S., Aton, S., Jha, S., Coleman, T., Seibt, J., Frank, M., Lack, L., Churches, O., Feng, S. Y. S., Cassaglia, P., Yu, V. Y. H., Walker, A. M., Kohler, M., Kennedy, D., Martin, J., van Den Heuvel, C., Lushington, K., Herron, K., Khurana, C., Sterr, A., Olivadoti, M., Toth, L., Opp, M., Dang-Vu, T., Degueldre, C., Gais, S., Dang-Vu, T. T., Desseilles, M., Philips, C., Chijavadze, E., Babilodze, M., Chkhartishvili, E., Nachkebia, N., Mchedlidze, O., Dzadzamia, S., Griffiths, R., Walker, A., Horovitz, S., Fukunaga, M., Carr, W., Picchioni, D., de Zwart, J., van Gelderen, P., Braun, A., Duyn, J., Hanlon, E. H., Faraguna, U., Vyazovskiy, V., Cirelli, C., Ocampo-Garcés, A., Ibáñez, F., López, S., Vivaldi, E., Torrealba, F., Romanowski, C. P. 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G., Owais, S., Alsuwat, K., Hamam, K., Zs, M., Boroojerdi, B., Giladi, N., Wood, D., Sherman, D., Chaudhuri, R., Partinen, M., Abdo, F., Bloem, B., Kremer, B., Verbeek, M., Cronlein, T., Mueller, U., Hajak, G., Zulley, J., Namba, K., Li, L., Mtsuura, M., Kaneita, Y., Ohida, T., Cappeliez, B., Moutrier, R., De, S., Dwivedi, S., Chambers, D., Gabbay, E., Watanabe, A., Valle, C., Kauati, A., Watanabe, R., Chediek, F., Botte, S., Azevedo, E., Kempf, J., Cizza, G., Torvik, S., Brancati, G., Smirne, N., Bruni, A., Goff, E., Freilich, S., Malaweera, A., Simonds, A., Mathias, C., Morrell, M., Rinsky, B., Fonarow, G., Gradinger, F. P., Boldt, C., Geyh, S., Stucki, A., Dahlberg, A., Michel, F., Savard, M.-H., Savard, J., Quesnel, C., Hirose, K., Takahara, M., Mizuno, K., Sadachi, H., Nagashima, Y., Yada, Y., Cheung, C.-F., Lau, C., Lai, W., Sin, K., Tam, C., Hellgren, J., Omenaas, E., Gíslason, T., Jögi, R., Franklin, K., Torén, K., Wang, F., Kadono, M., Shigeta, M., Nakazawa, A., Ueda, M., Fukui, M., Hasegawa, G., Yoshikawa, T., de Niet, G., Tiemens, B., Lendemeijer, B., Hutschemaekers, G., Gauthier, A.-K., Chevrette, T., Chevrier, E., Bouvier, H., Parry, B., Meliska, C., Nowakowski, S., Lopez, A., Martinez, F., Sorenson, D., Lien, M. L., Lattova, Z., Maurovich-Horvat, E., Nia, S., Pollmächer, T., Poulin, J., Chouinard, S., Stip, E., Guillem, F., Venne, D., Caouette, M., Lamont, M.-E., Lázár, A., Lázár, Z., Bíró, A., Gyõri, M., Tárnok, Z., Prekop, C., Gádoros, J., Halász, P., Bódizs, R., Okun, M., Hanusa, B., Hall, M., Wisner, K., Pereira, M., Kumar, R. A. J. E. S. H., Macey, P. A. U. L., Woo, M. A. R. Y., Serber, S. T. A. C. Y., Valladares, E. D. W. I. N., Harper, R. E. B. E. C. C. A., Harper, R. O. N. A. L. D., Puttonen, S., Härmä, M., Vahtera, J., Kivimäki, M., Lamarche, L., Hemmeter, U. M., Thum, A., Rocamora, R., Giesler, M., Haag, A., Dodel, R., Krieg, J. C., Shechter, A., L’Esperance, P., Boivin, D. B., Vu, M.-T., and Richards, H.
- Published
- 2007
- Full Text
- View/download PDF
24. Beta-cell M 3 muscarinic acetylcholine receptors as potential targets for novel antidiabetic drugs
- Author
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Zhu, L, Rossi, M, N M, Doliba, and Wess, J
- Published
- 2020
25. The photon-neutrino interaction induced by non-commutativity and astrophysical bounds
- Author
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Schupp, P., Trampetić, J., Wess, J., and Raffelt, G.
- Published
- 2004
- Full Text
- View/download PDF
26. Gauge theories on the $\kappa$-Minkowski spacetime
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Dimitrijević, M., Meyer, F., Möller, L., and Wess, J.
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- 2004
- Full Text
- View/download PDF
27. Deformed field theory on $\kappa$-spacetime
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Dimitrijević, M., Jonke, L., Möller, L., Tsouchnika, E., Wess, J., and Wohlgenannt, M.
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- 2003
- Full Text
- View/download PDF
28. Dysregulated hippocampal acetylcholine neurotransmission and impaired cognition in M2, M4 and M2/M4 muscarinic receptor knockout mice
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Tzavara, E T, Bymaster, F P, Felder, C C, Wade, M, Gomeza, J, Wess, J, McKinzie, D L, and Nomikos, G G
- Published
- 2003
- Full Text
- View/download PDF
29. The $Z \rightarrow \gamma \gamma,\;gg$ decays in the non-commutative standard model
- Author
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Behr, W., Deshpande, N. G., Duplancic, G., Schupp, P., Trampetic, J., and Wess, J.
- Published
- 2003
- Full Text
- View/download PDF
30. ACETYLCHOLINE AND M2 MUSCARINIC RECEPTOR CONTRIBUTE TO MODULATE SCHWANN CELL PROLIFERATION AND DIFFERENTIATION: S30-04
- Author
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Tata, A. M., Uggenti, C., De Stefano, M. E., Pisano, A., Costantino, M., Loreti, S., Talora, C., Wess, J., Magnaghi, V., and Ricordy, R.
- Published
- 2013
31. The standard model on non-commutative space-time
- Author
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Calmet, X., Jurčo, B., Schupp, P., Wess, J., and Wohlgenannt, M.
- Published
- 2002
- Full Text
- View/download PDF
32. Decoupling braided tensor factors
- Author
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Fiore, G., Steinacker, H., and Wess, J.
- Published
- 2001
- Full Text
- View/download PDF
33. Construction of non-Abelian gauge theories on noncommutative spaces
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Jurčo, B., Möller, L., Schraml, S., Schupp, P., and Wess, J.
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- 2001
- Full Text
- View/download PDF
34. External fields as intrinsic geometry
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Madore, J., Schraml, S., Schupp, P., and Wess, J.
- Published
- 2001
- Full Text
- View/download PDF
35. Enveloping algebra-valued gauge transformations for non-abelian gauge groups on non-commutative spaces
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Jurco, B., Schraml, S., Schupp, P., and Wess, J.
- Published
- 2000
- Full Text
- View/download PDF
36. Realization of the three-dimensional quantum Euclidean space by differential operators
- Author
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Schraml, S. and Wess, J.
- Published
- 2000
- Full Text
- View/download PDF
37. Gauge theory on noncommutative spaces
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Madore, J., Schraml, S., Schupp, P., and Wess, J.
- Published
- 2000
- Full Text
- View/download PDF
38. The geometry of a q-deformed phase space
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Cerchiai, B.L., Hinterding, R., Madore, J., and Wess, J.
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- 1999
- Full Text
- View/download PDF
39. q-deformed Lorentz-algebra in Minkowski phase space
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Rohregger, M. and Wess, J.
- Published
- 1999
- Full Text
- View/download PDF
40. Convergent perturbation theory for a q–deformed anharmonic oscillator
- Author
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Dick, R., Pollok-Narayanan, A., Steinacker, H., and Wess, J.
- Published
- 1999
- Full Text
- View/download PDF
41. $q$ $q$-deformed Hermite polynomials in $q$ $q$-quantum mechanics
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Hinterding, R. and Wess, J.
- Published
- 1999
- Full Text
- View/download PDF
42. Genetic identification of cholinergic mechanisms controlling sleep and wakefulness
- Author
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Niwa, Y., primary, Obo, H., additional, Wess, J., additional, and Sakurai, T., additional
- Published
- 2019
- Full Text
- View/download PDF
43. $q$ $q$-deformed Minkowski space based on a $q$ $q$-Lorentz algebra
- Author
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Cerchiai, B.L. and Wess, J.
- Published
- 1998
- Full Text
- View/download PDF
44. A q-deformation of the harmonic oscillator
- Author
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Lorek, A., Ruffing, A., and Wess, J.
- Published
- 1997
- Full Text
- View/download PDF
45. Muscarinic Acetylcholine Receptor Knockout Mice
- Author
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Wess, J., primary, Zhang, W., additional, Duttaroy, A., additional, Miyakawa, T., additional, Gomeza, J., additional, Cui, Y., additional, Basile, A. S., additional, Bymaster, F. P., additional, McKinzie, D. L., additional, Felder, C. C., additional, Deng, C., additional, and Yamada, M., additional
- Published
- 2004
- Full Text
- View/download PDF
46. Intraislet glucagon signaling is critical for maintaining glucose homeostasis
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Doliba, N.M., Matschinsky, F.M., Kaestner, K.H., Barella, L.F., Dattaroy, D., Hochgeschwender, U., Wess, J., Wilkins, K.J., Roth, B.L., Cui, Y., Pham, J., Wang, L., and Zhu, L.
- Subjects
endocrine system - Abstract
Glucagon, a hormone released from pancreatic a cells, plays a key role in maintaining proper glucose homeostasis and has been implicated in the pathophysiology of diabetes. In vitro studies suggest that intraislet glucagon can modulate the function of pancreatic ß cells. However, because of the lack of suitable experimental tools, the in vivo physiological role of this intraislet cross-talk has remained elusive. To address this issue, we generated a mouse model that selectively expressed an inhibitory designer GPCR (Gi DREADD) in a cells only. Drug-induced activation of this inhibitory designer receptor almost completely shut o? glucagon secretion in vivo, resulting in markedly impaired insulin secretion, hyperglycemia, and glucose intolerance. Additional studies with mouse and human islets indicated that intraislet glucagon stimulates insulin release primarily by activating β cell GLP-1 receptors. These fndings strongly suggest that intraislet glucagon signaling is essential for maintaining proper glucose homeostasis in vivo. Our work may pave the way toward the development of novel classes of antidiabetic drugs that act by modulating intraislet cross-talk between a and ß cells.
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- 2019
- Full Text
- View/download PDF
47. Allosteric modulation of β-cell M 3 muscarinic acetylcholine receptors greatly improves glucose homeostasis in lean and obese mice
- Author
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Zhu, L, Rossi, M, Cohen, A, Pham, J, Zheng, H, Dattaroy, D, Mukaibo, T, J E, Melvin, J L, Langel, Hattar, S, F H, Matschinsky, D H, Appella, M N, Doliba, and Wess J #Zhu L and Rossi, M have contributed equally to this work
- Published
- 2019
48. q-deformed phase space and its lattice structure
- Author
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Fichtmüller, M., Lorek, A., and Wess, J.
- Published
- 1996
- Full Text
- View/download PDF
49. Role of the M3 muscarinic acetylcholine receptor in β-cell function and glucose homeostasis
- Author
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Gautam, D., Han, S.-J., Duttaroy, A., Mears, D., Hamdan, F. F., Li, J. H., Cui, Y., Jeon, J., and Wess, J.
- Published
- 2007
50. Muscarinic acetylcholine receptor knockout mice: Phenotypical analysis and clinical implications
- Author
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Gomeza, J., primary, Yamada, M., additional, Duttaroy, A., additional, Zhang, W., additional, Makita, R., additional, Miyakawa, T., additional, Crawley, J., additional, Zhang, L., additional, Shannon, H., additional, Bymaster, F.P., additional, Felder, C.C., additional, Deng, C., additional, and Wess, J., additional
- Published
- 2002
- Full Text
- View/download PDF
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