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1. Lifestyle Aspects As A Predictor Of Pain Among Oldest-Old Primary Care Patients – A Longitudinal Cohort Study

Author

Mallon T, Eisele M, König HH, Brettschneider C, Röhr S, Pabst A, Weyerer S, Werle J, Mösch E, Weeg D, Fuchs A, Pentzek M, Heser K, Wiese B, Kleineidam L, Wagner M, Riedel-Heller S, Maier W, and Scherer M

Subjects
oldest-old, health-related aspects, pain prevention, longitudinal cohort study, chronic conditions, Geriatrics, RC952-954.6
Abstract

Tina Mallon,1 Marion Eisele,1 Hans-Helmut König,2 Christian Brettschneider,2 Susanne Röhr,3 Alexander Pabst,3 Siegfried Weyerer,4 Jochen Werle,4 Edelgard Mösch,5 Dagmar Weeg,5 Angela Fuchs,6 Michael Pentzek,6 Kathrin Heser,7 Birgitt Wiese,8 Luca Kleineidam,9 Michael Wagner,9 Steffi Riedel-Heller,3 Wolfgang Maier,7,9 Martin Scherer1 1Department of Primary Medical Care, Center for Psychosocial Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; 2Department of Health Economics and Health Services Research, Hamburg Center for Health Economics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; 3Institute of Social Medicine, Occupational Health and Public Health (ISAP), University of Leipzig, Leipzig, Germany; 4Central Institute of Mental Health, Medical Faculty Mannheim/Heidelberg University, Mannheim, Germany; 5Department of Psychiatry, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany; 6Institute of General Practice, Medical Faculty, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany; 7Department for Neurodegenerative Diseases and Geriatric Psychiatry, University Hospital Bonn, Bonn, Germany; 8Work Group Medical Statistics and IT-Infrastructure, Institute for General Practice, Hannover Medical School, Hannover, Germany; 9DZNE, German Center for Neurodegenerative Diseases, Bonn, GermanyCorrespondence: Tina MallonDepartment of Primary Medical Care, Center for Psychosocial Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, GermanyTel +49-40-741057164Fax +49-40-741053681Email t.mallon@uke.dePurpose: Dealing with the high prevalence of pain among the oldest-old (+75) is becoming a major health issue. Therefore, the aim of the study was to uncover health-related lifestyle behaviors (HLB) and age-related comorbidities which may predict, influence and prevent pain in old age.Patients and methods: In this longitudinal cohort study, data were obtained initially from 3.327 individuals aged 75+ from over 138 general practitioners (GP) during structured clinical interviews in 2003. Nine follow-ups (FU) were assessed until 2017. Available data from 736 individuals scoring in FU3 and FU7 were included in this analysis. Data were assembled in an ambulatory setting at participant’s homes. Associations were tested using a linear regression model (model 1) and ordered logistic regression model (model 2).Results: Statistical analyses revealed increased likelihood to experience pain for participants with comorbidities such as peripheral arterial disease (PAD) (coef. 13.51, P>t = 0.00) or chronic back pain (CBP) (coef. 6.64, P>t = 0.003) or higher body mass index (BMI) (coef. 0.57, P>t = 0.015) and, female gender (coef. 6.00, SE 3.0, t = 2.02, P>t = 0.044). Participants with medium education and former smokers showed significantly lower pain rating (coef. −5.05, P>t = 0.026; coef. −5.27, P>t = 0.026). Suffering from chronic back pain (OR = 2.03), osteoarthritis (OR = 1.49) or depressive symptoms (OR = 1.10) raised the odds to experience impairments in daily living due to pain. Physical activity showed no significant results.Conclusion: Chronic conditions such as PAD, or CBP, female gender and higher BMI may increase the risk of experiencing more pain while successful smoking cessation can lower pain ratings at old age. Early and consistent support through GPs should be given to older patients in order to prevent pain at old age.Keywords: oldest-old, health-related aspects, pain prevention, longitudinal cohort study, chronic conditions

Published
2019

5. Profile gedeckter und ungedeckter Versorgungsbedarfe der hochaltrigen Hausarztpatient:innen mit kognitiven Beeinträchtigungen und Demenz - Ergebnisse der AgeCoDe und AgeQualiDe Studie

Author

Kraake, S, Pabst, A, Bickel, H, Pentzek, M, Fuchs, A, Wiese, B, Oey, A, König, HH, Brettschneider, C, Scherer, M, Mallon, T, Lühmann, D, Maier, W, Wagner, M, Heser, K, Weyerer, S, Werle, J, Riedel-Heller, SG, Stein, J, Kraake, S, Pabst, A, Bickel, H, Pentzek, M, Fuchs, A, Wiese, B, Oey, A, König, HH, Brettschneider, C, Scherer, M, Mallon, T, Lühmann, D, Maier, W, Wagner, M, Heser, K, Weyerer, S, Werle, J, Riedel-Heller, SG, and Stein, J

Published
2024

8. Informelle Pflege bei Demenz nach Leistungsarten

Author

Brettschneider, C., Hajek, A., Stein, J., Luck, T., Mamone, S., Wiese, B., Mösch, E., Weeg, D., Fuchs, A., Pentzek, M., Werle, J., Weyerer, S., Mallon, T., van den Bussche, H., Heser, K., Wagner, M., Scherer, M., Maier, W., Riedel-Heller, S. G., and König, H.-H.

Published
2018
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20. Nanomedicínský přístup pro rychlou identifikaci virů za využití elektrochemických biosenzorů.

Author

Dunovská, K., Klapková, E., Fořtová, M., Werle, J., Petrus, J., Grondžák, T., Hosnedlová, B., Kotaška, K., Čepová, J., Průša, R., and Kizek, R.

Abstract

Copyright of General Practitioner / Praktický Lékař is the property of Czech Medical Association of JE Purkyne and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2022

22. P199 Effects of prefrontal cathodal tDCS on brain glutamate levels and resting state connectivity: A randomized, sham-controlled, cross-over trial in healthy volunteers

Author

Mezger, E., Rauchmann, B.S., Brunoni, A.R., Bulubas, L., Thielscher, A., Werle, J., Mortazavi, M., Karali, T., Stöcklein, S., Ertl-Wagner, B., Goerigk, S., Padberg, F., Keeser, D., Mezger, E., Rauchmann, B.S., Brunoni, A.R., Bulubas, L., Thielscher, A., Werle, J., Mortazavi, M., Karali, T., Stöcklein, S., Ertl-Wagner, B., Goerigk, S., Padberg, F., and Keeser, D.

Abstract

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Published
2020

26. Net costs of dementia by disease stage

Author

Leicht, H., Heinrich, S., Heider, D., Bachmann, C., Bickel, H., van den Bussche, H., Fuchs, A., Luppa, M., Maier, W., Mösch, E., Pentzek, M., Rieder-Heller, S. G., Tebarth, F., Werle, J., Weyerer, S., Wiese, B., Zimmermann, T., and König, H.-H.

Published
2011
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27. P199 Effects of prefrontal cathodal tDCS on brain glutamate levels and resting state connectivity: A randomized, sham-controlled, cross-over trial in healthy volunteers

Author

Mezger, E., primary, Rauchmann, B.S., additional, Brunoni, A.R., additional, Bulubas, L., additional, Thielscher, A., additional, Werle, J., additional, Mortazavi, M., additional, Karali, T., additional, Stöcklein, S., additional, Ertl-Wagner, B., additional, Goerigk, S., additional, Padberg, F., additional, and Keeser, D., additional

Published
2020
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30. Psychologische Interventionen für erwachsene Patienten mit ADHS – ein systematischer Review

Author

Scholz, LE, Werle, J, Philipsen, A, Schulze, M, and Gensichen, J

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

Hintergrund: Bis zu 3-5% der erwachsenen Bevölkerung leiden an der als Kinder- und Jugendkrankheit bekannten Aufmerksamkeitsdefizit-/ Hyperaktivitätsstörung (ADHS). Obwohl die pharmazeutische Behandlung bei Erwachsenen oftmals die Therapie der ersten Wahl darstellt, sollten [zum vollständigen Text gelangen Sie über die oben angegebene URL], 53. Kongress für Allgemeinmedizin und Familienmedizin

Published
2019
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32. Informelle Pflege bei Demenz nach Leistungsarten

Author

Brettschneider, C, Hajek, A, Stein, J, Luck, T, Mamone, S, Wiese, B, Mösch, E, Weeg, D, Fuchs, A, Pentzek, M, Werle, J, Weyerer, S, Mallon, T, Bussche, Hvd, Heser, K, Wagner, M, Scherer, M, Maier, W, Riedel-Heller, SG, König, HH, Brettschneider, C, Hajek, A, Stein, J, Luck, T, Mamone, S, Wiese, B, Mösch, E, Weeg, D, Fuchs, A, Pentzek, M, Werle, J, Weyerer, S, Mallon, T, Bussche, Hvd, Heser, K, Wagner, M, Scherer, M, Maier, W, Riedel-Heller, SG, and König, HH

Published
2018

34. Factors Affecting Functional Impairment among Elderly Germans - Results of a Longitudinal Study

Author

Horst Bickel, Posselt T, Wiese B, Werle J, Stein J, Scherer Jm, Hans-Helmut König, Tobias Luck, Michael Wagner, Edelgard Mösch, Kathrin Heser, Steinmann S, Pentzek M, W. Maier, Christian Brettschneider, Fuchs A, André Hajek, Steffi G. Riedel-Heller, Lange C, and Weyerer S

Subjects
Gerontology, Male, Longitudinal study, Aging, Activities of daily living, physiopathology [Cognitive Dysfunction], Population, Medicine (miscellaneous), Comorbidity, Cohort Studies, 03 medical and health sciences, 0302 clinical medicine, Germany, Activities of Daily Living, medicine, Dementia, psychology [Aging], Humans, Cognitive Dysfunction, 030212 general & internal medicine, ddc:610, Longitudinal Studies, Prospective Studies, Prospective cohort study, education, Depression (differential diagnoses), Aged, Aged, 80 and over, education.field_of_study, Nutrition and Dietetics, business.industry, Depression, physiopathology [Dementia], medicine.disease, physiology [Aging], prevention & control [Dementia], psychology [Depression], Ageing, Spouse, Female, Geriatrics and Gerontology, business, 030217 neurology & neurosurgery
Abstract

To investigate causal factors of functional impairment in old age in a longitudinal approach. A population-based prospective cohort study. Elderly individuals were recruited via GP offices at six study centers in Germany. They were observed every 1.5 years over six waves. Three thousand two hundred fifty-six people aged 75 years and older at baseline. Functional impairment was quantified by the Lawton and Brody Instrumental Activities of Daily Living scale (IADL) and the Barthel-Index (BI). Fixed effects regressions revealed that functional impairment (IADL; BI) increased significantly with ageing (β=-.2; β=-1.1), loss of a spouse (β=.5; β=-3.1), not living alone in private household (β=-1.2; β=-5.5), depression (solely significant for IADL: β=.6) and dementia (β=-2.3; β=-18.2). The comorbidity score did not affect functional impairment. Our findings underline the relevance of changes in sociodemographic variables as well as the occurrence of depression or dementia for functional impairment. While several of these causal factors for functional decline in the oldest old are inevitable, some may not be, such as depression. Therefore, developing interventional strategies to prevent depression might be a fruitful approach in order to delay functional impairment in old age.

Published
2017
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37. Does visual impairment affect social ties in late life? Findings of a multicenter prospective cohort study in Germany

Author

Hajek, A., Brettschneider, C., Luehmann, D., Eisele, M., Mamone, S., Wiese, B., Weyerer, S., Werle, J., Pentzek, M., Fuchs, A., Stein, J., Luck, T., Bickel, H., Weeg, D., Heser, K., Jessen, F., Maier, W., Scherer, M., Riedel-Heller, S. G., Koenig, H. -H., Hajek, A., Brettschneider, C., Luehmann, D., Eisele, M., Mamone, S., Wiese, B., Weyerer, S., Werle, J., Pentzek, M., Fuchs, A., Stein, J., Luck, T., Bickel, H., Weeg, D., Heser, K., Jessen, F., Maier, W., Scherer, M., Riedel-Heller, S. G., and Koenig, H. -H.

Abstract

To investigate how visual impairment affects social ties in late life longitudinally. Population-based prospective cohort study. Individuals in old age were recruited via general practitioners' offices (at six study centers) in Germany. They were interviewed every 18 months. Individuals aged 75 years and above at baseline. Follow-up wave 2 (36 months after baseline, n=2,443) and wave 4 (72 months after baseline, n=1,618) were used for the analyses presented here. Social ties were assessed using the 14-item form of the questionnaire for social support (F-SozU K-14). Visual impairment was self-rated on a three level Likert scale (no impairment, mild visual impairment, or severe/profound visual impairment). Adjusting for sociodemographic factors, hearing impairment and comorbidity, fixed effects regressions revealed that the onset of mild visual impairment decreased the social support score, in particular the emotional support score. Additionally, the onset of mild hearing impairment decreased the social support score in men. Moreover, increasing age decreased the social support score in the total sample and in both sexes. Loss of spouse and increasing comorbidity did not affect the social support score. Our results highlight the importance of visual impairment for social ties in late life. Consequently, appropriate strategies in order to delay visual impairment might help to maintain social ties in old age.

Published
2017

38. Unmet care needs in the oldest old primary care patients with cognitive disorders: Results of the AgeCoDe & AgeQualiDe Study

Author

Stein, J, Pabst, A, Luck, T, Lühmann, D, Heser, K, Jessen, F, Bickel, H, Mösch, E, Pentzek, M, Fuchs, A, Wiese, B, Mamone, S, König, HH, Brettschneider, C, Werle, J, Scherer, M, Maier, W, Weyerer, S, Riedel-Heller, SG, Stein, J, Pabst, A, Luck, T, Lühmann, D, Heser, K, Jessen, F, Bickel, H, Mösch, E, Pentzek, M, Fuchs, A, Wiese, B, Mamone, S, König, HH, Brettschneider, C, Werle, J, Scherer, M, Maier, W, Weyerer, S, and Riedel-Heller, SG

Published
2017

40. Age of major depression onset, depressive symptoms, and risk for subsequent dementia: results of the German Study on Ageing, Cognition, and Dementia in Primary Care Patients (AgeCoDe)

Author

Heser, K., Tebarth, F., Leicht, H., Bohnau, Harald, Pinsdorf, Ursula, Busch, Thomas, Keller, Gisela, Fuchs-Romer, Susanne, Beisel, Wolfgang, Richter-Polynice, Birgitt, Cupsa, Florinela, Unkelbach, Roland Matthias, Schiller, Gerhard, Pentzek, M., Damanakis, Barbara, Frenkel, Michael, Ebeling, Klaus-Wolfgang, Berger, Pauline, Gillhausen, Kurt, Hellmessen, Uwe, Hummerich, Helga, Heede, Hans-Christian, Kormann, Boguslaw-Marian, Peters, Josef, Fuchs, A., Schott, Ulrich, Matzies, Dirk, Schumacher, Andre, Oliver Flettner, Tim, Thraen, Winfried, Siegmund, Harald, Levacher, Claus, Blankenstein, Tim, Lamborelle, Eliane, Hollstein, Ralf, Riedel-Heller, S. G., Hoffmann, Edna, Ghane, Ingeborg, Claß, Regine, Meier, Stefan-Wolfgang, Moers, Leo W, Wundram, Udo, Schmitt, Klaus, Missghian, Rastin, Spallek, Karin, Schlosser, Christiane, Luppa, M., Groß, Kathrin, Bouche, Winfried, Linn, Ursula, Bormann, Gundula, Schulze, Gerhard, Stelter, Klaus, Gatermann, Heike, Fischer-Radizi, Doris, Witt, Peter, Kavka, Stefanie, Prokein, J., Klotzl, Gunther, Baumho, Michael, Oberlander, Maren, Schiewe, Cornelia, Hufnagel, Jorg, Kressel, Marei, Kebschull, Michael, Wagner, Christine, Burkhardt, Fridolin, Hase, Martina, Scherer, M., Houcken, Karl-Heinz, Zebidi, Christiane, Brohan, Johann, Russ, Christiane, Bethge, Frank, Rughase-Block, Gisela, Lorenzen, Margret, Elsen, Arne, Korte, Daniela, Jedicke, Ursula, Group, Age CoDe Study, Zoras, Constantin, Pfeil-Woltmann, Gabriele, Kaiser, Martin, Bruns, Johannes, Homann, Joachim, Gorgon, Georg, Middendorf, Niklas, Menschke, Kay, Bayer, Hans H, Maier, Wolfgang, Jesse, Nadine, Dahlke, Marcus, Lipp, Thomas, Amm, Martina, Bauer, Horst, Rauchmaul, Gabriele, Ebert, Hans Jochen, Gabriel-Mu, Angelika, Taut, Hans-Christian, Voß, Hella, Scherer, Martin, Schmidt, Holger, Hager, Eva, Tunze, Bettina, Paschke, Thomas, Assmann, Heinz-Michael, Rahnefeld, Uwe, Striegler, Petra, Gierth, Marga, Boehm, Margret, Harnisch, Dagmar, Wiese, B., van den Bussche, Hendrik, Kornisch-Koch, Simone, Hambsch, Frank, Herzig, Cornelia, Georgi, Astrid, Schwarzmann, Erhard, Schinagl, Gerd, Pehnke, Ulrike, Dayab, Mohammed, Brosig, Michael, Sperling, Volkmar, Abholz, Heinz-Harald, Lebuser, Frank, Hagert, Detlef, Arnold, Gerhard, Bauer, Viet-Harold, Becker, Hartwig, Becker, Hermine, Besier, Werner, Grella, Hartmut, Grimm, Hans Heinrich, Heck, Petra, Bachmann, Cadja, Hemler, Werner, Henn, Eric, Mayer, Manfred, Orlovius, Gerhard, Renz, Helmut, Scheer, Georg, Schilp, Michael, Schmid, Angela, Schneider, Matthias, Uhle, Christian, Bickel, Horst, Weinga, Brigitte, Wochele, Eberhard, Wolfram, Bernhard, Hofmann, Andreas, Allwein, Eugen, Ruile, Helmut, Koeppel, Andreas, Dick, Peter, Holtz, Friedrich, Schmidt, Gabriel, Blank, Wolfgang, Fischer, Lutz-Ingo, Thaller, Johann, Bloß, Guntram, Kreuzer, Franz, Holthausen, Gunther, Ludwig Maier, Karl, Krebs, Walter, Mohr, Christoph, Koschine, Heinz, Ellersdorfer, Richard, Speth, Michael, Kleinhans, Maria, Koutsouva-Sack, Panagiota, Staudinger, Gabriele, Eiber, Johann, Thiel, Stephan, Gold, Cornelia, Nalbach, Andrea, Reichert, Kai, Neef, Martin, Eifflaender-Gorfer, Sandra, Fleischmann, Viktor, Mayer, Natalija, Spiegl, Andreas, Renner, Fritz, Weishappel-Ketisch, Eva, Kochems, Thomas, Hunger, Hartmut, Hofbeck, Marianne, Neumeier, Alfred, Goldhofer, Elfriede, Eisele, Marion, Bommer, Thomas, Vollmuth, Reinhold, Lanzinger, Klaus, Pauli, Ramona, Lindner, Jutta, Brandt, Gerlinde, Hohentanner, Otto, Porz, Peter, Zimmerhackl, Bernd, Hallwachs, Alexander, Ernst, Annette, Haseke, Claudia, Ploch, Andreas, Swobodnik, Monika, Jost, Detlev, Narr, Renate, Nehmann, Gabriele, Eder, Christiane, Pillin, Helmut, Loth, Frank, Fritz, Nicola, Fuchs, Angela, Rafferzeder, Michael, Zirpel, Dietmar, Romberg, Heinz-Peter, Liese, Hanna, Burfent, Inge, von Aswege, Johann, Honig, Wolf-Dietrich, Schu, Heribert, Marx, Manfred, Straimer, Annemarie, Eisele, M., Heser, Kathrin, Uhlenbrock, Arndt, Werner, Michael, Gobel-Schlatholt, Maria, Prechtel, Eberhard, Kaschell, Hans-Jurgen, Weckbecker, Klaus, Alfen, Theodor, Eimers-Kleene, Jorg, Fischer, Klaus, Weisbach, Wolf-Rudiger, Jessen, Frank, Tschoke, Martin, Fliedner, Michael, Hodgson, Binjamin, Hamkens, Werner, Ackermann, Angela, Kaduszkiewicz, Hanna, Kirsch, Michael, Miasnikov, Vladimir, Kormann, Marian, Kaufeler, Teresa, Lu, Dieter, Wirtz, Clemens, Kohler, Mirjam, Krug, Bernd-Uwe, Hutter, Petra, Lau, Dietrich, Schroder-Hoch, Ursula, Herzog, Wolfgang, Weidner, Klaus, Witt, Otto-Peter, Konig, Hans-Helmut, Titova, Ljudmila, Moritz, Andrea, Lipp, Ina, Koppara, Alexander, Muhlmann, Ute, Bra, Barbara, Ziehbold, Sabine, Lange, Carolin, Schmalbruch, Ina, Ka, Gunter, Bo, Hanna, Ludwig, Ingrid, Noky, Adolf, Leicht, Hanna, Perleberg, Helmut, Rieder, Carsten, Rosen, Michael, Kunzendorf, Gerhard, Wachter, Jurgen, Weingartner, Brigitte, Luck, Tobias, Willhauck, Hans-Georg, Herbst, Helga, Friedrich, Peter, Kirchner, Hans-Georg, Kirchner, Elke, Knauer, Luitpold, Bickel, H., Luppa, Melanie, Holtz, Karl-Friedrich, Schmid, Elmar, Kahmann, Ulf, nther Holthausen, Gu, Mosch, Edelgard, Reich, Paul, Stahl, Eberhard, Lunow, Reinhold, Undritz, Klaus, Voss, Bernd, Spreer, Achim, Brenig, Oliver, Eich, Ralf, Vossel, Angelika, Leggewie, Dieter, Olbrich, Julia, Schmidt, Angelika, Aghdai-Heuser, Nahid, Witten, Lutz, Igel, Michael, Hodgson, Benjamin, Hoff, Bernhard, Pentzek, Michael, Luttringhaus, Dieter, Opitz, Rolf, Bausch, Jurgen, Mecking, Dirk, Ganßauge, Friederike, Peters, Elmar, Wester, Alfons, Petersen, Werner, Prokein, Jana, Daase, Martin, Rusing, Martin, von Sethe, Christoph, Borngra, Wilmhard, Colling-Pook, Brigitte, Weidner, Ullrich, Rieger, Peter, Witte, Lutz, Busch, Hans-Wilhelm, Unger, Jurgen, Schumacher, Anna, Preis, Angela, Mann, Michael, Haeberle, Ernst, Kohler, Horst, Sliwiok, Helmut, Deest, Harald, Ackermann-Korner, Margret, Reinstorff, Dieter, Schluter, Christamaria, Heinrichs, Henrik, Riedel-Heller, Steffi, Dankwarth, Ole, Bose, Michael, Ryll, Ulricke, Bauer, Reinhard, Schnakenbeck, Sven, Beckmann, Karin, Callsen, Annegret, Schiewe, Ewa, Gehm, Holger, Lambert, Volker, Stein, Janine, Hinkel-Reineke, Karin, Stolzenbach, Carl-Otto, Berdin, Peter, Windler, Friedhelm, Weidnitzer, Sabine, Rosenkranz, Erika, Letzien, Norbert, Klossek, Doris, Liebsch, Martin, Steinmann, Susanne, Zwicker, Andrea, Hantel, Ulrike, Pilz, Monika, Kirschner, Volker, Arnold, Rainer, Poser, Ulrich, Barthel, Wolfgang, Blechinger, Fritz, Fritz, Reiner Walter, Junemann, Susanne, Köhler, M., Tebarth, Franziska, Kirsch, Gabriele, Kulinna, Jurgen, Legner-Gorke, Andreas, Lehr, Christa, Meer, Wolfgang, Panzer, Christina, Raabe, Achim, Schmidt-Back, Helga, Wagner, Michael, Gunter Stieglitz, Hans, von der Heide, Marie-Luise, Kirchner, Georg, Kastner, Jorg, Janssen, Ulrike, Standl, Albert, Gottl, Clemens, Franze, Marianne, Moser, Gerhard, Blumm, Almut, Weber, Petra, Poetsch, Wolfgang, Puppe, Heinrich, Weeg, Dagmar, Specht, Gerd, Badmann, Leonard, Leveringhaus, May, Posern, Michael, Potkowski, Ralph, Schwandner, Michael, Weigert, Rudolf, Huber, Christoph, Werle, Jochen, Weyerer, Siegfried, Wiese, Birgitt, Wolfsgruber, Steffen, Zimmermann, Thomas, Adrian, Claudia, Mösch, E., Gulle, Peter, Schutzendorf, Heribert, Benz, Elisabeth, Werner, Klaus-Michael, Weyerer, S., Stahlschmidt, Markus, Dorn, Jurgen, Menke, Helmut, Werle, J., Sievert, Erik, Krockert, Ulrich, Salingre, Gabriele, Morchen, Christian, Raab, Peter, Baszenski, Angela, Loth, Clarli, Knaak, Christian, Hotte, Peter, Pieper, Jorg, König, H-H, Wassermann, Dirk, Leyendecker, Hans Josef, Gohde, Gerhard, Simons, Barbara, Brunger, Achim, Petersen, Uwe, Wahl, Heike, Tewes, Rainer, Junghans-Kullmann, Doris, and Grimm-Kraft, Angela

Subjects
Male, Risk, epidemiology [Cognition Disorders], Aging, medicine.medical_specialty, epidemiology [Alzheimer Disease], etiology [Alzheimer Disease], epidemiology [Depressive Disorder, Major], epidemiology [Germany], epidemiology [Dementia], Prodrome, Alzheimer Disease, Germany, medicine, History of depression, psychology [Aging], Humans, Dementia, ddc:610, Age of Onset, Risk factor, Psychiatry, Applied Psychology, Depression (differential diagnoses), Aged, Aged, 80 and over, epidemiology [Depression], Depressive Disorder, Major, Primary Health Care, Depression, business.industry, Hazard ratio, Cognition, Middle Aged, medicine.disease, Psychiatry and Mental health, Female, etiology [Dementia], Age of onset, Cognition Disorders, business, Follow-Up Studies
Abstract

BackgroundWhether late-onset depression is a risk factor for or a prodrome of dementia remains unclear. We investigated the impact of depressive symptoms and early- v. late-onset depression on subsequent dementia in a cohort of elderly general-practitioner patients (n = 2663, mean age = 81.2 years).MethodRisk for subsequent dementia was estimated over three follow-ups (each 18 months apart) depending on history of depression, particularly age of depression onset, and current depressive symptoms using proportional hazard models. We also examined the additive prediction of incident dementia by depression beyond cognitive impairment.ResultsAn increase of dementia risk for higher age cut-offs of late-onset depression was found. In analyses controlling for age, sex, education, and apolipoprotein E4 genotype, we found that very late-onset depression (aged ⩾70 years) and current depressive symptoms separately predicted all-cause dementia. Combined very late-onset depression with current depressive symptoms was specifically predictive for later Alzheimer's disease (AD; adjusted hazard ratio 5.48, 95% confidence interval 2.41–12.46, p ConclusionsDepression might be a prodrome of AD but not of dementia of other aetiology as very late-onset depression in combination with current depressive symptoms, possibly emerging as a consequence of subjectively perceived worrisome cognitive deterioration, was most predictive. As depression parameters and subjective memory impairment predicted AD independently of objective cognition, clinicians should take this into account.

Published
2012
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41. Maßnahmen zur besseren interprofessionellen Zusammenarbeit im Pflegeheim - Entwicklung in einem mehrstufigen qualitativen Forschungsprozess

Author

Mueller, C.A., Fleischmann, N., Cavazzini, C., Geister, C., Tetzlaff, B., Hoell, A., Werle, J., Scherer, M., and Hummers-Pradier, E.

Subjects
ddc: 610, Maßnahmenentwicklung, interprofessionelle Zusammenarbeit, 610 Medical sciences, Medicine, Pflegeheim
Abstract

Hintergrund: Die Gesundheit von Pflegeheimbewohnern kann durch gute interprofessionelle Zusammenarbeit von Hausärzten und Pflegekräften positiv beeinflusst werden. Wir haben unter Einbezug der wesentlichen Akteursgruppen (Bewohnern, Angehörigen, Hausärzten, Pflegekräften) Maßnahmen[zum vollständigen Text gelangen Sie über die oben angegebene URL], 49. Kongress für Allgemeinmedizin und Familienmedizin

Published
2015

42. 'Bin hingegangen, habe eine Blutentnahme gemacht und bin wieder abgehauen.' Wie erleben Hausärzte den Heimbesuch?

Author

Fleischmann, N., Tetzlaff, B., Werle, J., Geister, C., Scherer, M., Hummers-Pradier, E., and Müller, C.

Subjects
ddc: 610, Kommunikation, 610 Medical sciences, Medicine, Pflegeheim, Qualitative Studie
Abstract

Hintergrund: Mit der komplexen Versorgungssituation von Pflegeheimbewohnern kommt dem Heimbesuch eine besondere Bedeutung zu. Obwohl bessere Vergütung sowie organisatorische Optimierungsmaßnahmen diskutiert werden, ist über das Erleben des Besuches aus der Perspektive der Hausärzte[zum vollständigen Text gelangen Sie über die oben angegebene URL], 49. Kongress für Allgemeinmedizin und Familienmedizin

Published
2015

43. Predictors of frailty in old age-results of a longitudinal study

Author

Hajek, Andr, Brettschneider, C., Posselt, T., Lange, C., Mamone, S., Wiese, B., Weyerer, S., Werle, J., Fuchs, A., Pentzek, M., Stein, J., Luck, T., Bickel, H., Mosch, E., Heser, K., Jessen, F., Maier, W., Scherer, M., Riedel-Heller, S. G., Konig, H. -H., Hajek, Andr, Brettschneider, C., Posselt, T., Lange, C., Mamone, S., Wiese, B., Weyerer, S., Werle, J., Fuchs, A., Pentzek, M., Stein, J., Luck, T., Bickel, H., Mosch, E., Heser, K., Jessen, F., Maier, W., Scherer, M., Riedel-Heller, S. G., and Konig, H. -H.

Abstract

To investigate time-dependent predictors of frailty in old age longitudinally. Population-based prospective cohort study. Elderly individuals were recruited via GP offices at six study centers in Germany. The course of frailty was observed over 1.5 years (follow up wave 4 and follow up wave 5). 1,602 individuals aged 80 years and older (mean age 85.4 years SD 3.2, with mean CSHA CFS 3.5 SD 1.6) at follow up wave 4. Frailty was assessed by using the Canadian Study of Health and Aging Clinical Frailty Scale (CSHA CFS), ranging from 1 (very fit) to 7 (severely frail). Fixed effects regressions revealed that frailty increased significantly with increasing age (=.2) as well as the occurrence of depression (=.5) and dementia (=.8) in the total sample. Changes in marital status and comorbidity did not affect frailty. While the effects of depression and dementia were significant in women, these effects did not achieve statistical significance in men. Our findings highlight the role of aging as well as the occurrence of dementia and depression for frailty. Specifically, in order to delay frailty in old age, developing interventional strategies to prevent depression might be a fruitful approach.

Published
2016

44. 'Was soll ich mit einem Arzt?' Medizinische Versorgung in Pflegeheimen aus der Perspektive der Bewohner - Eine qualitative Untersuchung

Author

Cavazzini, C., Müller, C., Fleischmann, N., Geister, C., Hoell, A., Scherer, M., Tetzlaff, B., Werle, J., Weyerer, S., and Hummers-Pradier, E.

Subjects
Interprofessionelle Zusammenarbeit, Pflegeheimbewohner, ddc: 610, Medizinische Versorgung, 610 Medical sciences, Medicine
Abstract

Hintergrund: In den kommenden Jahrzehnten ist mit einem deutlichen Zuwachs an Bewohnern in der stationären Altenpflege zu rechnen. Eine gute interprofessionelle Zusammenarbeit innerhalb der medizinischen Versorgung im Pflegeheim wird daher zunehmend an Bedeutung gewinnen. Das übergeordnete[for full text, please go to the a.m. URL], 48. Kongress für Allgemeinmedizin und Familienmedizin

Published
2014

45. Hausbesuch oder Visite? Erwartungen und Erfahrungen von Pflegekräften zur interprofessionellen Zusammenarbeit mit Hausärzten während des Heimbesuchs

Author

Fleischmann, N, Hoell, A, Müller, C, Werle, J, Cavazzini, C, Geister, C, Tetzlaff, B, Scherer, M, Weyerer, S, and Hummers-Pradier, E

Subjects
Interprofessionelle Zusammenarbeit, ddc: 610, Pflegeheime, 610 Medical sciences, Medicine, Pflege und Medizin
Abstract

Hintergrund: In Pflegeheimen lebt eine große Anzahl an Bewohnern mit komplexen medizinischen und pflegerischen Bedarfen. Für eine adäquate Versorgung ist eine enge Zusammenarbeit der Gesundheitsberufe erforderlich. Aufgrund der besonderen Konstellation, dass Pflegeheime stationäre[for full text, please go to the a.m. URL], 48. Kongress für Allgemeinmedizin und Familienmedizin

Published
2014
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49. Einflussfaktoren auf die Pflegebedürftigkeit im Längsschnitt

Author

Hajek, A., additional, Brettschneider, C., additional, Ernst, A., additional, Posselt, T., additional, Mamone, S., additional, Wiese, B., additional, Weyerer, S., additional, Werle, J., additional, Pentzek, M., additional, Fuchs, A., additional, Stein, J., additional, Luck, T., additional, Bickel, H., additional, Mösch, E., additional, Kleineidam, L., additional, Heser, K., additional, Maier, W., additional, Scherer, M., additional, Riedel-Heller, S., additional, and König, H.-H., additional

Published
2016
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