Fan, Lou, Tiesong, Zhang, Cheng, Ming, Jing, Ma, Meilan, Wang, and Wenjuan, Zeng
OBJECTIVE: Explore the clinical features of cervical lymph node lesions in children with different pathological types, and provide help for the early diagnosis of the disease. METHOD: The data of 73 children with cervical lymph node disease diagnosed by lymph node biopsy were collected, and the gender composition, age distribution, lymph node characteristics and clinical manifestations of children with different pathological types were analyzed. RESULT: Among the 73 children with cervical lymph node disease, the incidence of male patients in the benign disease group was less than that of female ones, and the incidence of male patients in the malignant disease group was greater than that of female ones, the difference in gender composition between the two groups was statistically significant(P < 0.05). The benign disease group had the largest proportion in the school-age period(27.4%), and the malignant disease group had a larger proportion in the preschool period(21.9%) and school-age period(20.5%), both groups had a relatively smaller proportion in the infant and adolescent period, the difference in age distribution within the group was statistically significant(P < 0.01). Among the various pathological types, the proportion of 73 children with lymph node inflammatory reactive hyperplasia was the largest, 35.6%(26/73), and was mainly at school age; the second was Hodgkin's lymphoma, accounting for 20.5%(15/73), mainly in the preschool and school age. The average maximum transverse diameter of lymph nodes in the malignant disease group was greater than that in the benign disease group(P < 0.05). The lymph nodes in the benign disease group were mainly distributed in areas Ⅰ, Ⅱ, and Ⅲ, and the lymph nodes in the malignant disease group were mainly distributed in areas Ⅱ, Ⅲ, Ⅳ, and Ⅴ, there was a statistically significant difference in the distribution of enlarged lymph nodes between the two groups(P < 0.01). CONCLUSION: Different pathological types of cervical lymph node lesions in children are different in gender composition, age distribution, lymph node size and distribution, and cervical lymph node lesions in children have their own characteristics.