18 results on '"Wendt HW"'
Search Results
2. Incidence of sudden cardiac death, myocardial infarction and far- and near-transyears.
- Author
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Halberg F, Cornélissen G, Otsuka K, Fiser B, Mitsutake G, Wendt HW, Johnson P, Gigolashvili M, Breus T, Sonkowsky R, Chibisov SM, Katinas G, Siegelova J, Dusek J, Singh RB, Berri BL, and Schwartzkopff O
- Subjects
- Czech Republic epidemiology, Geography, Georgia (Republic) epidemiology, Hong Kong epidemiology, Humans, United States epidemiology, Chronobiology Phenomena, Death, Sudden, Cardiac epidemiology, Myocardial Infarction epidemiology, Solar Activity
- Abstract
We analyzed cycles with periods, tau, in the range of 0.8-2.0 years, characterizing, mostly during 1999-2003, the incidence of sudden cardiac death (SCD), according to the International Classification of Diseases, 10th revision (ICD10), code I46.1. In the tau range examined, only yearly components could be documented in time series from North Carolina, USA; Tbilisi, Georgia; and Hong Kong, in the latter two locations based on relatively short time series. By contrast, in Minnesota, USA, we found only a component with a longer than (= trans) yearly (transyearly) tau of 1.39 years; the 95% confidence interval (CI) of the tau extended from 1.17 to 1.61 years, falling into the category of transyears (defined as a tau and a 95% CI between 1.0 and 2.0 years, with the limits of the 95% CI of the spectral component's tau overlapping neither of these lengths). During the same span from 1999 to 2003 in Arkansas, USA, a component of about 1-year in length was present, and in addition, one with a tau of 1.69 year with a CI extending from 1.29 to 2.07 years, a far-transyear candidate, far-transyears being defined as having a tau with a CI between 1.20 and 2.0 year, with the CI overlapping neither of these lengths. In the Czech Republic, there was also a calendar-yearly tau and one of 1.76 years. In the latter two geographic/geomagnetic areas, the about-yearly and the longer cycles' amplitudes were of similar prominence. The taus are only candidate transyears; the 95% CIs of their taus overlap the 2-year length. When a series on SCD from 1994 to 2003 from the Czech Republic was analyzed, the 95% CI of the transyear's tau no longer overlapped the 2-year length. Transyears were also found in the Czech Republic for myocardial infarctions (MI), meeting the original transyear definition in both a shorter and a longer series. Moreover, in the 1994-2003 series on MI from the Czech Republic, a near-transyear was also found, meeting the definition of a period with a 95% CI overlapping neither precisely 1.0 year nor 1.2 years, along with a far-transyear, defined as a tau between 1.2 and 2.0 years, again with the 95% CI covering neither of these lengths. Herein, we discuss near- and far-transyears more generally in the light of their background in physics and the concept of reciprocal cyclicities.
- Published
- 2005
- Full Text
- View/download PDF
3. Chronomics, neuroendocrine feedsidewards and the recording and consulting of nowcasts--forecasts of geomagnetics.
- Author
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Jozsa R, Halberg F, Cornélissen G, Zeman M, Kazsaki J, Csernus V, Katinas GS, Wendt HW, Schwartzkopff O, Stebelova K, Dulkova K, Chibisov SM, Engebretson M, Pan W, Bubenik GA, Nagy G, Herold M, Hardeland R, Hüther G, Pöggeler B, Tarquini R, Perfetto F, Salti R, Olah A, Csokas N, Delmore P, Otsuka K, Bakken EE, Allen J, and Amory-Mazaudin C
- Subjects
- Animals, Circadian Rhythm, Feedback, Hypothalamus metabolism, Lighting, Melatonin metabolism, Pineal Gland metabolism, Rats, Rats, Wistar, Chronobiology Phenomena, Electromagnetic Fields, Neurosecretory Systems physiology, Solar Activity
- Abstract
A multi-center four-hourly sampling of many tissues for 7 days (00:00 on April 5-20:00 to April 11, 2004), on rats standardized for 1 month in two rooms on antiphasic lighting regimens happened to start on the day after the second extremum of a moderate double magnetic storm gauged by the planetary geomagnetic Kp index (which at each extremum reached 6.3 international [arbitrary] units) and by an equatorial index Dst falling to -112 and -81 nT, respectively, the latter on the first day of the sampling. Neuroendocrine chronomes (specifically circadian time structures) differed during magnetically affected and quiet days. The circadian melatonin rhythm had a lower MESOR and lower circadian amplitude and tended to advance in acrophase, while the MESOR and amplitude of the hypothalamic circadian melatonin rhythm were higher during the days with the storm. The circadian parameters of circulating corticosterone were more labile during the days including the storm than during the last three quiet days. Feedsidewards within the pineal-hypothalamic-adrenocortical network constitute a mechanism underlying physiological and probably also pathological associations of the brain and heart with magnetic storms. Investigators in many fields can gain from at least recording calendar dates in any publication so that freely available information on geomagnetic, solar and other physical environmental activity can be looked up. In planning studies and before starting, one may gain from consulting forecasts and the highly reliable nowcasts, respectively.
- Published
- 2005
- Full Text
- View/download PDF
4. Chronoastrobiology: proposal, nine conferences, heliogeomagnetics, transyears, near-weeks, near-decades, phylogenetic and ontogenetic memories.
- Author
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Halberg F, Cornélissen G, Regal P, Otsuka K, Wang Z, Katinas GS, Siegelova J, Homolka P, Prikryl P, Chibisov SM, Holley DC, Wendt HW, Bingham C, Palm SL, Sonkowsky RP, Sothern RB, Pales E, Mikulecky M, Tarquini R, Perfetto F, Salti R, Maggioni C, Jozsa R, Konradov AA, Kharlitskaya EV, Revillam M, Wan C, Herold M, Syutkina EV, Masalov AV, Faraone P, Singh RB, Singh RK, Kumar A, Singhs R, Sundaram S, Sarabandi T, Pantaleoni G, Watanabe Y, Kumagai Y, Gubin D, Uezono K, Olah A, Borer K, Kanabrockia EA, Bathina S, Haus E, Hillman D, Schwartzkopff O, Bakken EE, and Zeman M
- Subjects
- Consensus Development Conferences as Topic, Humans, Time, Chronobiology Phenomena physiology, Evolution, Molecular, Phylogeny, Research Design, Solar Activity
- Abstract
"Chronoastrobiology: are we at the threshold of a new science? Is there a critical mass for scientific research?" A simple photograph of the planet earth from outer space was one of the greatest contributions of space exploration. It drove home in a glance that human survival depends upon the wobbly dynamics in a thin and fragile skin of water and gas that covers a small globe in a mostly cold and vast universe. This image raised the stakes in understanding our place in that universe, in finding out where we came from and in choosing a path for survival. Since that landmark photograph was taken, new astronomical and biomedical information and growing computer power have been revealing that organic life, including human life, is and has been connected to invisible (non-photic) forces, in that vast universe in some surprising ways. Every cell in our body is bathed in an external and internal environment of fluctuating magnetism. It is becoming clear that the fluctuations are primarily caused by an intimate and systematic interplay between forces within the bowels of the earth--which the great physician and father of magnetism William Gilbert called a 'small magnet'--and the thermonuclear turbulence within the sun, an enormously larger magnet than the earth, acting upon organisms, which are minuscule magnets. It follows and is also increasingly apparent that these external fluctuations in magnetic fields can affect virtually every circuit in the biological machinery to a lesser or greater degree, depending both on the particular biological system and on the particular properties of the magnetic fluctuations. The development of high technology instruments and computer power, already used to visualize the human heart and brain, is furthermore making it obvious that there is a statistically predictable time structure to the fluctuations in the sun's thermonuclear turbulence and thus to its magnetic interactions with the earth's own magnetic field and hence a time structure to the magnetic fields in organisms. Likewise in humans, and in at least those other species that have been studied, computer power has enabled us to discover statistically defined endogenous physiological rhythms and further direct effects that are associated with these invisible geo- and heliomagnetic cycles. Thus, what once might have been dismissed as noise in both magnetic and physiological data does in fact have structure. And we may be at the threshold of understanding the biological and medical meaning and consequences of these patterns and biological-astronomical linkages as well. Structures in time are called chronomes; their mapping in us and around us is called chronomics. The scientific study of chronomes is chronobiology. And the scientific study of all aspects of biology related to the cosmos has been called astrobiology. Hence we may dub the new study of time structures in biology with regard to influences from cosmo- helio- and geomagnetic rhythms chronoastrobiology. It has, of course, been understood for centuries that the movements of the earth in relation to the sun produce seasonal and daily cycles in light energy and that these have had profound effects on the evolution of life. It is now emerging that rhythmic events generated from within the sun itself, as a large turbulent magnet in its own right, can have direct effects upon life on earth. Moreover, comparative studies of diverse species indicate that there have also been ancient evolutionary effects shaping the endogenous chronomic physiological characteristics of life. Thus the rhythms of the sun can affect us not only directly, but also indirectly through the chronomic patterns that solar magnetic rhythms have created within our physiology in the remote past. For example, we can document the direct exogenous effects of given specific solar wind events upon human blood pressure and heart rate. We also have evidence of endogenous internal rhythms in blood pressure and heart rate that are close to but not identical to the period length of rhythms in the solar wind. These were installed genetically by natural selection at some time in the distant geological past. This interpretive model of the data makes the prediction that the internal and external influences on heart rate and blood pressure can reinforce or cancel each other out at different times. A study of extensive clinical and physiological data shows that the interpretive model is robust and that internal and external effects are indeed augmentative at a statistically significant level. Chronoastrobiological studies are contributing to basic science--that is, our understanding is being expanded as we recognize heretofore unelaborated linkages of life to the complex dynamics of the sun, and even to heretofore unelaborated evolutionary phenomena. Once, one might have thought of solar storms as mere transient 'perturbations' to biology, with no lasting importance. Now we are on the brink of understanding that solar turbulences have played a role in shaping endogenous physiological chronomes. There is even documentation for correlations between solar magnetic cycles and psychological swings, eras of belligerence and of certain expressions of sacred or religious feelings. Chronoastrobiology can surely contribute to practical applications as well as to basic science. It can help develop refinements in our ability to live safely in outer space, where for example at the distance of the moon the magnetic influences of the sun will have an effect upon humans unshielded by the earth's native magnetic field. We should be better able to understand these influences as physiological and mechanical challenges, and to improve our estimations of the effects of exposure. Chronoastrobiology moreover holds great promise in broadening our perspectives and powers in medicine and public health right here upon the surface of the earth. Even the potential relevance of chronoastrobiology for practical environmental and agricultural challenges cannot be ruled out at this early stage in our understanding of the apparently ubiquitous effects of magnetism and hence perhaps of solar magnetism on life. The evidence already mentioned that fluctuations in solar magnetism can influence gross clinical phenomena such as rates of strokes and heart attacks, and related cardiovascular variables such as blood pressure and heart rate, should illustrate the point that the door is open to broad studies of clinical implications. The medical value of better understanding magnetic fluctuations as sources of variability in human physiology falls into several categories: 1) The design of improved analytical and experimental controls in medical research. Epidemiological analyses require that the multiple sources causing variability in physiological functions and clinical phenomena be identified and understood as thoroughly as possible, in order to estimate systematic alterations of any one variable. 2) Preventive medicine and the individual patients'care. There are no flat 'baselines', only reference chronomes. Magnetic fluctuations can be shown statistically to exacerbate health problems in some cases. The next step should be to determine whether vulnerable individuals can be identified by individual monitoring. Such vulnerable patients may then discover that they have the option to avoid circumstances associated with anxiety during solar storms, and/or pay special attention to their medication or other treatments. Prehabilitation by self-help can hopefully complement and eventually replace much costly rehabilitation. 3) Basic understanding of human physiological mechanisms. The chronomic organization of physiology implies a much more subtle dynamic integration of functions than is generally appreciated. All three categories of medical value in turn pertain to the challenges for space science of exploring and colonizing the solar system. The earth's native magnetic field acts like an enormous umbrella that offers considerable protection on the surface from harsh solar winds of charged particles and magnetic fluxes. The umbrella becomes weaker with distance from the earth and will offer little protection for humans, other animals, and plants in colonies on the surface of the moon or beyond. Thus it is important before more distant colonization is planned or implemented to better understand those magnetism-related biological- solar interactions that now can be studied conveniently on earth. (ABSTRACT TRUNCATED)
- Published
- 2004
- Full Text
- View/download PDF
5. Multiple resonances among time structures, chronomes, around and in US. Is an about 1.3-year periodicity in solar wind built into the human cardiovascular chronome?
- Author
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Cornélissen G, Masalov A, Halberg F, Richardson JD, Katinas GS, Sothern RB, Watanabe Y, Syutkina EV, Wendt HW, Bakken EE, and Romanov Y
- Subjects
- Adult, Aged, Humans, Longitudinal Studies, Middle Aged, Minnesota epidemiology, Nonlinear Dynamics, Periodicity, Wind, Blood Pressure physiology, Chronobiology Phenomena, Heart Rate physiology, Myocardial Infarction mortality, Solar Activity
- Abstract
Aims: Velocity changes in the solar wind, recorded by satellite (IMP8 and Wind) are characterized by a solar cycle dependent approximately 1.3-year component. The presence of any approximately 1.3-year component in human blood pressure (BP) and heart rate (HR) and in mortality from myocardial infarction (MI) is tested and its relative prominence compared to the 1.0-year variation., Materials and Methods: Around the clock manual or automatic BP and HR measurements from four subjects recorded over 5 to 35 years and a 29-year record of mortality from MI in Minnesota were analyzed by linear-nonlinear rhythmometry. Point and 95% confidence interval (CI) estimates were obtained for the approximately 1.3-year period and amplitude. The latter is compared with the 1.0-year amplitude for BP and HR records concurrent to the solar data provided by one of us (JDR)., Results: An approximately 1.3-year component is resolved nonlinearly for MI, with a period of 1.23 (95% CI: 1.21; 1.26) year. This component was invariably validated with statistical significance for BP and HR by linear rhythmometry. Nonlinearly, the 95% CI for the 1.3-year amplitude did not overlap zero in 11 of the 12 BP and HR series. Given the usually strong synchronizing role of light and temperature, it is surprising that 5 of the 12 cardiovascular series had a numerically larger amplitude of the 1.3-year versus the precise 1.0-year component. The beating of the approximately 1.3-year and 1.0-year components was shown by gliding spectra on actual and simulated data., Discussion and Conclusion: The shortest 5-year record (1998-2003) revealed an approximately 1.3-year component closer to the solar wind speed period characterizing the entire available record (1994-2003) than that for the concurrent 5-year span. Physiological variables may resonate with non-photic environmental cycles that may have entered the genetic code during evolution.
- Published
- 2004
6. Blood pressure self-surveillance for health also reflects 1.3-year Richardson solar wind variation: spin-off from chronomics.
- Author
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Halberg F, Cornélissen G, Schack B, Wendt HW, Minne H, Sothern RB, Watanabe Y, Katinas G, Otsuka K, and Bakken EE
- Subjects
- Humans, Self Care methods, Time Factors, Blood Pressure Monitoring, Ambulatory methods, Chronobiology Phenomena, Solar Activity, Wind
- Abstract
Self-experimentation concerns not only scientists, but also each individual for the sake of his/her chronobiologic health and science literacy, eventually to be acquired in primary and secondary education. Public education ensures that everybody who knows how to read or write can dispense with the service of a costly scribe. At all ages, public education can teach equally well how to find out whether one's blood pressure (BP) and heart rate (HR) responds to an increase in sodium intake with a rise, with no change or with a decrease in BP. This task and many others could become a matter of informed self-surveillance. Whenever there are inter-individual, sometimes opposite differences in response, government-sponsored trials on groups that do not consider such differences cannot solve what only the individual can do, at first by help from schools. Eventually special institutions may be designed for chronomics, the monitoring, interpretation and archivization of chronomes (time structures; from chronos = time and nomos = rule) of biological variables, also charged with a demographic analyzing and reporting system. Each individual's properly coded record, to guard confidentiality, becomes part of a promptly accessible database for one's own needs and for society's requirements. What individuals and small groups started as chronobiology, what is immediately available on back burners, as a service by an international project on the biosphere and the cosmos (BIOCOS) (corne001@umn.edu) could become a public system of planned surveillance archivization of one's rhythms from womb to tomb. Alterations of a rhythm's amplitude or acrophase or of a deterministic or other chaotic endpoint, such as a correlation dimension and approximate entropy, or of a standard deviation, among a multitude of other endpoints, can signal (in the otherwise neglected normal range) reversible risk elevations. If these elevated risks are detected and prompt the institution of countermeasures, such prehabilitation can save the cost of rehabilitation or of long-term care after morbid events; suffering also can be prevented such as that by those who are unlucky enough to helplessly survive a massive brain, heart or societal "stroke". As an equally important dividend, science gains in basic and applied terms, as illustrated herein by the demonstration of a trans-year, an approximately 1.3 to 1.6-year, heretofore unknown component of the human BP and HR spectrum, beating with the circannual component and characterizing the same data. Chronomically interpreted self-monitoring is a civic duty for both one's health and everybody's science.
- Published
- 2003
- Full Text
- View/download PDF
7. [The origin of the biological week from data on the rhythm of cardiac contractions in people during the solar activity cycle].
- Author
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Cornelissen G, Halberg F, Breus TK, Watanabe Y, Sothern RB, Haus E, Kleitman E, Wendt HW, and Bingham C
- Subjects
- Adaptation, Physiological genetics, Genome, Humans, Male, Myocardial Contraction, Periodicity, Solar Activity
- Abstract
A human biologic week in the heart rate variations was compared with the variations of the sunspot area and geomagnetic activity over the solar cycle. The low ratio of amplitude of circaseptan rhythm to that of circadian rhythm in the heart rate of several clinically healthy men who did around-the-clock self-measurements in a number of years coincides with the period of anomalously low amplitude of circaseptan rhythm of the solar activity. Results herein suggest that physiologic circaseptan rhythms are built into the genome being adapted evolutionary to the original heliogeomagnetic environmental circaseptans.
- Published
- 1998
8. Resonance of about-weekly human heart rate rhythm with solar activity change.
- Author
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Cornelissen G, Halberg F, Wendt HW, Bingham C, Sothern RB, Haus E, Kleitman E, Kleitman N, Revilla MA, Revilla M Jr, Breus TK, Pimenov K, Grigoriev AE, Mitish MD, Yatsyk GV, and Syutkina EV
- Subjects
- Adult, Aged, Aged, 80 and over, Female, Humans, Male, Middle Aged, Chronobiology Phenomena, Circadian Rhythm, Heart Rate physiology, Solar Activity
- Abstract
In several human adults, certain solar activity rhythms may influence an about 7-day rhythm in heart rate. When no about-weekly feature was found in the rate of change in sunspot area, a measure of solar activity, the double amplitude of a circadian heart rate rhythm, approximated by the fit of a 7-day cosine curve, was lower, as was heart rate corresponds to about-weekly features in solar activity and/or relates to a sunspot cycle.
- Published
- 1996
9. Statistical significance without biologic signification is not enough: illustrative example.
- Author
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Cornélissen G, Sothern RB, Wendt HW, Tarquini B, Antuñano M, Siegelová J, Fiser B, Dusek J, Prikryl P, and Halberg F
- Subjects
- Adult, Biometry, Blood Pressure physiology, Cosmic Radiation, Female, Geological Phenomena, Geology, Heart Rate physiology, Humans, Infant, Newborn, Magnetics, Male, Chronobiology Phenomena physiology
- Published
- 1994
10. Beyond circadian chronorisk.
- Author
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Wendt HW
- Subjects
- Humans, Solar Energy, Morbidity, Periodicity
- Published
- 1993
11. Circadian characteristics of urinary epinephrine and norepinephrine from healthy young women in Japan and U.S.A.
- Author
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Lakatua DJ, Haus E, Halberg F, Halberg E, Wendt HW, Sackett-Lundeen LL, Berg HG, Kawasaki T, Ueno M, and Uezono K
- Subjects
- Adult, Female, Humans, Japan, Reference Values, United States, Circadian Rhythm, Epinephrine urine, Norepinephrine urine
- Abstract
Clinically healthy diurnally active young adult women were studied during the same season (March) at the Universities of Kyushu (Fukuoka City, Japan) and of Minnesota (Minneapolis, U.S.A.), under comparable conditions, except that the habitual diets were not changed. The subjects (20 Japanese and 16 Americans of mixed Caucasian background) were studied over a single 24-hr span. Urine was collected at 4-hr intervals. A circadian rhythm in total urinary norepinephrine excretion showed similar characteristics in Japanese and Americans. In epinephrine excretion, the Japanese women showed a statistically significantly higher amplitude with higher peak values, but no statistically significant difference in the rhythm-adjusted mean. This intergroup difference is strictly time dependent; it does not come to the fore in urine samples covering the nocturnal rest span of the subjects.
- Published
- 1986
- Full Text
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12. Spurious correlation, revisited: a new look at the quantitative outcomes of sampling heterogeneous groups and/or at the wrong time.
- Author
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Wendt HW
- Subjects
- Analysis of Variance, Factor Analysis, Statistical, Humans, Methods, Psychometrics, Statistics as Topic
- Published
- 1976
13. POINTS OR ORIGIN FOR INFANT ECOLOGIES: RELIGION AND PURCHASE OF DEVICES AFFECTING PRE-VERBAL MOBILITY.
- Author
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WENDT HW
- Subjects
- Child, Humans, Infant, Child Care, Infant Care, Religion, Religion and Psychology
- Published
- 1965
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14. Obligations to self and society in the United States and Germany.
- Author
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McCLELLAND DC, STURR JF, KNAPP RH, and WENDT HW
- Subjects
- Germany, Humans, United States, Personality, Personality Disorders
- Published
- 1958
- Full Text
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15. Early circannual rhythms and adult human behaviour: components of a chronobehavioural theory, and critique of persistent artifacts.
- Author
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Wendt HW
- Subjects
- Adult, Anxiety, Arousal, Circadian Rhythm, Conflict, Psychological, Darkness, Female, Gambling, Humans, Imprinting, Psychological, Infant, Light, Male, Maternal Behavior, Mother-Child Relations, Seasons, Social Behavior, Verbal Behavior, Behavior, Models, Psychological, Periodicity
- Published
- 1974
16. [The effects of stimulants on projective behavior].
- Author
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WENDT HW and CASPAR R
- Subjects
- Caffeine pharmacology, Central Nervous System Agents, Central Nervous System Stimulants pharmacology, Projective Techniques
- Published
- 1954
17. [Group test determine the critical fusion frequency in binocular vision, changes caused by caffeine medication and by normal days work].
- Author
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MUCHER H and WENDT HW
- Subjects
- Humans, Caffeine, Vision, Binocular, Vision, Ocular, Work
- Published
- 1951
18. [Behavior models of non-scientists: a biographical and motivation correlation of the perceived relationship between expectancy and incentive].
- Author
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Wendt HW
- Subjects
- Female, Humans, Male, Sex Factors, Achievement, Decision Making, Models, Psychological, Motivation, Perception
- Published
- 1967
- Full Text
- View/download PDF
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