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1,188 results on '"Wells, Philip S"'

9. Accuracy of physicians’ intuitive risk estimation in the diagnostic management of pulmonary embolism: an individual patient data meta-analysis

Author

van Maanen, Rosanne, Martens, Emily S.L., Takada, Toshihiko, Roy, Pierre-Marie, de Wit, Kerstin, Parpia, Sameer, Kraaijpoel, Noémie, Huisman, Menno V., Wells, Philip S., Le Gal, Grégoire, Righini, Marc, Freund, Yonathan, Galipienzo, Javier, van Es, Nick, Blom, Jeanet W., Moons, Karel G.M., Rutten, Frans H., van Smeden, Maarten, Klok, Frederikus A., Geersing, Geert-Jan, and Luijken, Kim

Published
2023
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13. Predicting major bleeding during extended anticoagulation for unprovoked or weakly provoked venous thromboembolism

Author

Wells, Philip S., Tritschler, Tobias, Khan, Faizan, Anderson, David R., Kahn, Susan R., Lazo-Langner, Alejandro, Carrier, Marc, Le Gal, Grégoire, Castellucci, Lana A., Shah, Vinay, Kaatz, Scott, Kearon, Clive, Solymoss, Susan, Zide, Russell, Schulman, Sam, Chagnon, Isabelle, Mallick, Ranjeeta, Rodger, Marc A., and Kovacs, Michael J.

Published
2022
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14. Long‐term risk of recurrent venous thromboembolism among patients receiving extended oral anticoagulant therapy for first unprovoked venous thromboembolism: A systematic review and meta‐analysis

Author

Khan, Faizan, Tritschler, Tobias, Kimpton, Miriam, Wells, Philip S., Kearon, Clive, Weitz, Jeffrey I., Büller, Harry R., Raskob, Gary E., Ageno, Walter, Couturaud, Francis, Prandoni, Paolo, Palareti, Gualtiero, Legnani, Cristina, Kyrle, Paul A., Eichinger, Sabine, Eischer, Lisbeth, Becattini, Cecilia, Agnelli, Giancarlo, Vedovati, Maria Cristina, Geersing, Geert‐Jan, Takada, Toshihiko, Cosmi, Benilde, Aujesky, Drahomir, Marconi, Letizia, Palla, Antonio, Siragusa, Sergio, Bradbury, Charlotte A., Parpia, Sameer, Mallick, Ranjeeta, Lensing, Anthonie W.A., Gebel, Martin, Grosso, Michael A., Shi, Minggao, Thavorn, Kednapa, Hutton, Brian, Le Gal, Gregoire, Rodger, Marc, and Fergusson, Dean

Published
2021
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16. Venous Thromboembolism Prophylaxis in Critically Ill Adults: A Systematic Review and Network Meta-analysis

Author

Fernando, Shannon M., Tran, Alexandre, Cheng, Wei, Sadeghirad, Behnam, Arabi, Yaseen M., Cook, Deborah J., Møller, Morten Hylander, Mehta, Sangeeta, Fowler, Robert A., Burns, Karen E.A., Wells, Philip S., Carrier, Marc, Crowther, Mark A., Scales, Damon C., English, Shane W., Kyeremanteng, Kwadwo, Kanji, Salmaan, Kho, Michelle E., and Rochwerg, Bram

Published
2021
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17. Balancing risks of recurrent venous thromboembolism and bleeding with extended anticoagulation: a decision analysis

Author

MS Interne Geneeskunde, Interne Geneeskunde Vasculaire, Medische Staf Spoedeisende Hulp, de Winter, Maria A., Thavorn, Kednapa, Hageman, Steven H.J., Nijkeuter, Mathilde, Wells, Philip S., MS Interne Geneeskunde, Interne Geneeskunde Vasculaire, Medische Staf Spoedeisende Hulp, de Winter, Maria A., Thavorn, Kednapa, Hageman, Steven H.J., Nijkeuter, Mathilde, and Wells, Philip S.

Published
2024

19. Antithrombotic Therapy for VTE Disease: Compendium and Review of CHEST Guidelines 2012-2021

Author

HAG Trombose, Circulatory Health, Stevens, Scott M, Woller, Scott C, Baumann Kreuziger, Lisa, Doerschug, Kevin, Geersing, Geert-Jan, Klok, Frederikus A, King, Christopher S, Murin, Susan, Vintch, Janine R E, Wells, Philip S, Wasan, Suman, Moores, Lisa K, HAG Trombose, Circulatory Health, Stevens, Scott M, Woller, Scott C, Baumann Kreuziger, Lisa, Doerschug, Kevin, Geersing, Geert-Jan, Klok, Frederikus A, King, Christopher S, Murin, Susan, Vintch, Janine R E, Wells, Philip S, Wasan, Suman, and Moores, Lisa K

Published
2024

25. DNA methylation age is associated with an altered hemostatic profile in a multiethnic meta-analysis

Author

Ward-Caviness, Cavin K., Huffman, Jennifer E., Everett, Karl, Germain, Marine, van Dongen, Jenny, Hill, W. David, Jhun, Min A., Brody, Jennifer A., Ghanbari, Mohsen, Du, Lei, Roetker, Nicholas S., de Vries, Paul S., Waldenberger, Melanie, Gieger, Christian, Wolf, Petra, Prokisch, Holger, Koenig, Wolfgang, O'Donnell, Christopher J., Levy, Daniel, Liu, Chunyu, Truong, Vinh, Wells, Philip S., Trégouët, David-Alexandre, Tang, Weihong, Morrison, Alanna C., Boerwinkle, Eric, Wiggins, Kerri L., McKnight, Barbara, Guo, Xiuqing, Psaty, Bruce M., Sotoodenia, Nona, Boomsma, Dorret I., Willemsen, Gonneke, Ligthart, Lannie, Deary, Ian J., Zhao, Wei, Ware, Erin B., Kardia, Sharon L.R., Van Meurs, Joyce B.J., Uitterlinden, Andre G., Franco, Oscar H., Eriksson, Per, Franco-Cereceda, Anders, Pankow, James S., Johnson, Andrew D., Gagnon, France, Morange, Pierre-Emmanuel, de Geus, Eco J.C., Starr, John M., Smith, Jennifer A., Dehghan, Abbas, Björck, Hanna M., Smith, Nicholas L., and Peters, Annette

Published
2018
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27. Ruling out pulmonary embolism across different healthcare settings: A systematic review and individual patient data meta-analysis

Author

Geersing, Geert-Jan, Takada, Toshihiko, Klok, Frederikus A., Büller, Harry R., Courtney, D. Mark, Freund, Yonathan, Galipienzo, Javier, Le Gal, Gregoire, Ghanima, Waleed, Kline, Jeffrey A., Huisman, Menno V., Moons, Karel G. M., Perrier, Arnaud, Parpia, Sameer, Robert-Ebadi, Helia, Righini, Marc, Roy, Pierre-Marie, van Smeden, Maarten, Stals, Milou A. M., Wells, Philip S., de Wit, Kerstin, Kraaijpoel, Noémie, and van Es, Nick

Subjects
Pulmonary embolism -- Diagnosis, Diagnosis -- Comparative analysis -- Evaluation, Biological sciences
Abstract

Background The challenging clinical dilemma of detecting pulmonary embolism (PE) in suspected patients is encountered in a variety of healthcare settings. We hypothesized that the optimal diagnostic approach to detect these patients in terms of safety and efficiency depends on underlying PE prevalence, case mix, and physician experience, overall reflected by the type of setting where patients are initially assessed. The objective of this study was to assess the capability of ruling out PE by available diagnostic strategies across all possible settings. Methods and findings We performed a literature search (MEDLINE) followed by an individual patient data (IPD) meta-analysis (MA; 23 studies), including patients from self-referral emergency care (n = 12,612), primary healthcare clinics (n = 3,174), referred secondary care (n = 17,052), and hospitalized or nursing home patients (n = 2,410). Multilevel logistic regression was performed to evaluate diagnostic performance of the Wells and revised Geneva rules, both using fixed and adapted D-dimer thresholds to age or pretest probability (PTP), for the YEARS algorithm and for the Pulmonary Embolism Rule-out Criteria (PERC). All strategies were tested separately in each healthcare setting. Following studies done in this field, the primary diagnostic metrices estimated from the models were the 'failure rate' of each strategy-i.e., the proportion of missed PE among patients categorized as 'PE excluded' and 'efficiency'-defined as the proportion of patients categorized as 'PE excluded' among all patients. In self-referral emergency care, the PERC algorithm excludes PE in 21% of suspected patients at a failure rate of 1.12% (95% confidence interval [CI] 0.74 to 1.70), whereas this increases to 6.01% (4.09 to 8.75) in referred patients to secondary care at an efficiency of 10%. In patients from primary healthcare and those referred to secondary care, strategies adjusting D-dimer to PTP are the most efficient (range: 43% to 62%) at a failure rate ranging between 0.25% and 3.06%, with higher failure rates observed in patients referred to secondary care. For this latter setting, strategies adjusting D-dimer to age are associated with a lower failure rate ranging between 0.65% and 0.81%, yet are also less efficient (range: 33% and 35%). For all strategies, failure rates are highest in hospitalized or nursing home patients, ranging between 1.68% and 5.13%, at an efficiency ranging between 15% and 30%. The main limitation of the primary analyses was that the diagnostic performance of each strategy was compared in different sets of studies since the availability of items used in each diagnostic strategy differed across included studies; however, sensitivity analyses suggested that the findings were robust. Conclusions The capability of safely and efficiently ruling out PE of available diagnostic strategies differs for different healthcare settings. The findings of this IPD MA help in determining the optimum diagnostic strategies for ruling out PE per healthcare setting, balancing the trade-off between failure rate and efficiency of each strategy., Author(s): Geert-Jan Geersing 1,*, Toshihiko Takada 1,2, Frederikus A. Klok 3, Harry R. Büller 4, D. Mark Courtney 5, Yonathan Freund 6, Javier Galipienzo 7, Gregoire Le Gal 8, Waleed [...]

Published
2022
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32. Covariate-specific ROC curve analysis can accommodate differences between covariate subgroups in the evaluation of diagnostic accuracy

Author

Lee, Jenny, primary, van Es, Nick, additional, Takada, Toshihiko, additional, Klok, Frederikus A., additional, Geersing, Geert-Jan, additional, Blume, Jeffrey, additional, Bossuyt, Patrick M., additional, Büller, Harry R., additional, Courtney, D Mark, additional, Freund, Yonathan, additional, Galipienzo, Javier, additional, Le Gal, Gregoire, additional, Ghanima, Waleed, additional, Kline, Jeffrey A., additional, Huisman, Menno V., additional, Moons, Karel G.M., additional, Perrier, Arnaud, additional, Parpia, Sameer, additional, Robert-Ebadi, Helia, additional, Righini, Marc, additional, Roy, Pierre-Marie, additional, van Smeden, Maarten, additional, Stals, Milou A.M., additional, Wells, Philip S., additional, de Wit, Kerstin, additional, and Kraaijpoel, Noémie, additional

Published
2023
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33. Accuracy of physicians' intuitive risk estimation in the diagnostic management of pulmonary embolism: An Individual Patient Data Meta-Analysis

Author

HAG Trombose, Epi Methoden, Cancer, JC onderzoeksprogramma Methodology, HAG Hart- Vaatziekten, Circulatory Health, JC onderzoeksprogramma Cardiovascular Health, Epi Methoden Team 3, Infection & Immunity, Maanen, Rosanne van, Martens, Emily S L, Takada, Toshihiko, Roy, Pierre-Marie, de Wit, Kerstin, Parpia, Sameer, Kraaijpoel, Noémie, Huisman, Menno V, Wells, Philip S, Le Gal, Grégoire, Righini, Marc, Freund, Yonathan, Galipienzo, Javier, van Es, Nick, Blom, Jeanet W, Moons, Karel G M, Rutten, Frans H, Smeden, Maarten van, Klok, Frederikus A, Geersing, Geert-Jan, Luijken, Kim, HAG Trombose, Epi Methoden, Cancer, JC onderzoeksprogramma Methodology, HAG Hart- Vaatziekten, Circulatory Health, JC onderzoeksprogramma Cardiovascular Health, Epi Methoden Team 3, Infection & Immunity, Maanen, Rosanne van, Martens, Emily S L, Takada, Toshihiko, Roy, Pierre-Marie, de Wit, Kerstin, Parpia, Sameer, Kraaijpoel, Noémie, Huisman, Menno V, Wells, Philip S, Le Gal, Grégoire, Righini, Marc, Freund, Yonathan, Galipienzo, Javier, van Es, Nick, Blom, Jeanet W, Moons, Karel G M, Rutten, Frans H, Smeden, Maarten van, Klok, Frederikus A, Geersing, Geert-Jan, and Luijken, Kim

Published
2023

34. Redefining clinical venous thromboembolism phenotypes: a novel approach using latent class analysis

Author

MS Interne Geneeskunde, Cardiovasculaire Epi Team 7B, Epi Infectieziekten, Circulatory Health, Medische Staf Spoedeisende Hulp, de Winter, Maria A., Uijl, Alicia, Büller, Harry R., Carrier, Marc, Cohen, Alexander T., Hansen, John Bjarne, Kaasjager, Karin H.A.H., Kakkar, Ajay K., Middeldorp, Saskia, Raskob, Gary E., Sørensen, Henrik Toft, Wells, Philip S., Nijkeuter, Mathilde, Dorresteijn, Jannick A.N., MS Interne Geneeskunde, Cardiovasculaire Epi Team 7B, Epi Infectieziekten, Circulatory Health, Medische Staf Spoedeisende Hulp, de Winter, Maria A., Uijl, Alicia, Büller, Harry R., Carrier, Marc, Cohen, Alexander T., Hansen, John Bjarne, Kaasjager, Karin H.A.H., Kakkar, Ajay K., Middeldorp, Saskia, Raskob, Gary E., Sørensen, Henrik Toft, Wells, Philip S., Nijkeuter, Mathilde, and Dorresteijn, Jannick A.N.

Published
2023

35. Recurrent venous thromboembolism and bleeding with extended anticoagulation: the VTE-PREDICT risk score

Author

MS Interne Geneeskunde, Epi Infectieziekten, Circulatory Health, Interne Geneeskunde Vasculaire, Medische Staf Spoedeisende Hulp, De Winter, Maria A., Büller, Harry R., Carrier, Marc, Cohen, Alexander T., Hansen, John Bjarne, Kaasjager, Karin A.H., Kakkar, Ajay K., Middeldorp, Saskia, Raskob, Gary E., Sørensen, Henrik T., Visseren, Frank L.J., Wells, Philip S., Dorresteijn, Jannick A.N., Nijkeuter, Mathilde, Braekkan, Sigrid K., Burggraaf, Louise, Cannegieter, Suzanne C., Farjat, Alfredo, Pap, Akos Ferenc, Goldhaber, Samuel, Grosso, Michael, Horváth-Puhó, Erzsebet, Lensing, Anthonie W.A., Pieper, Karen, Schulman, Sam, Shi, Minggao, Virdone, Saverio, MS Interne Geneeskunde, Epi Infectieziekten, Circulatory Health, Interne Geneeskunde Vasculaire, Medische Staf Spoedeisende Hulp, De Winter, Maria A., Büller, Harry R., Carrier, Marc, Cohen, Alexander T., Hansen, John Bjarne, Kaasjager, Karin A.H., Kakkar, Ajay K., Middeldorp, Saskia, Raskob, Gary E., Sørensen, Henrik T., Visseren, Frank L.J., Wells, Philip S., Dorresteijn, Jannick A.N., Nijkeuter, Mathilde, Braekkan, Sigrid K., Burggraaf, Louise, Cannegieter, Suzanne C., Farjat, Alfredo, Pap, Akos Ferenc, Goldhaber, Samuel, Grosso, Michael, Horváth-Puhó, Erzsebet, Lensing, Anthonie W.A., Pieper, Karen, Schulman, Sam, Shi, Minggao, and Virdone, Saverio

Published
2023

38. DVT Management and Outcome Trends, 2001 to 2014

Author

Monreal, Manuel, Decousus, Hervè, Prandoni, Paolo, Brenner, Benjamin, Barba, Raquel, Di Micco, Pierpaolo, Bertoletti, Laurent, Schellong, Sebastian, Tzoran, Inna, Reis, Abilio, Bosevski, Marijan, Bounameaux, Henri, Malý, Radovan, Wells, Philip, Papadakis, Manolis, Agudo, P., Aibar, M.A., Akasbi, M., Alcalde-Manero, M., Andújar, V., Arcelus, J.I., Ballaz, A., Barba, R., Barrón, M., Barrón-Andrés, B., Bascuñana, J., Blanco-Molina, A., Cañas, I., Casado, I., de Miguel, J., del Toro, J., Díaz, S., Díaz-Peromingo, J.A., Falgá, C., Fernández-Capitán, C., Font, C., Font, L., Gallego, P., García-Bragado, F., García-Rodenas, M., Gómez, V., González, C.J., Grau, E., Guirado, L., Gutiérrez, J., Hernández, G., Hernández-Blasco, L., Isern, V., Jara-Palomares, L., Jaras, M.J., Jiménez, D., Lobo, J.L., López-Jiménez, L., López-Reyes, R., López-Sáez, J.B., Lorente, M.A., Lorenzo, A., Madridano, O., Maestre, A., Marchena, P.J., Martín, M., Martín-Antorán, J.M., Martín-Martos, F., Monreal, M., Morales, M.V., Nauffal, D., Nieto, J.A., Nieto, S., Núñez, M.J., Orbegoso, C., Otalora, S., Otero, R., Pagán, B., Pedrajas, J.M., Pérez, C., Pérez, G., Peris, M.L., Pons, I., Porras, J.A., Reig, O., Riera-Mestre, A., Rivas, A., Rodríguez, C., Rodríguez-Dávila, M.A., Rosa, V., Rosa-Murillo, A.S., Ruiz-Giménez, N., Sahuquillo, J.C., Sala, M.C., Sampériz, A., Sánchez, R., Sanz, O., Soler, S., Suriñach, J.M., Tolosa, C., Trujillo-Santos, J., Uresandi, F., Valero, B., Valle, R., Vela, J., Vidal, G., Vilar, C., Villalta, J., Xifre, B., Vanassche, T., Verhamme, P., Wells, P., Hirmerova, J., Malý, R., Tomko, T., Celis, G., Salgado, E., Sánchez, G.T., Bertoletti, L., Bura-Riviere, A., Farge-Bancel, D., Hij, A., Mahé, I., Merah, A., Quere, I., Papadakis, M., Braester, A., Brenner, B., Tzoran, I., Apollonio, A., Barillari, G., Bertone, A., Bilora, F., Bucherini, E., Ciammaichella, M., De Ciantis, P., Dentali, F., Di Micco, P., Duce, R., Ferrazzi, P., Grandone, E., Lessiani, G., Lodigiani, C., Mastroiacovo, D., Pace, F., Pesavento, R., Pinelli, M., Poggio, R., Prandoni, P., Rosa, M., Rota, L., Tiraferri, E., Tonello, D., Tufano, A., Venturelli, U., Visonà, A., Zalunardo, B., Drucka, E., Kigitovica, D., Skride, A., Mafalda, A., Ribeiro, J.L., Sousa, M.S., Bosevski, M., Zdraveska, M., Bounameaux, H., Mazzolai, L., Morillo, Raquel, Jiménez, David, Aibar, Miguel Ángel, Mastroiacovo, Daniela, Wells, Philip S., Sampériz, Ángel, Saraiva de Sousa, Marta, Muriel, Alfonso, and Yusen, Roger D.

Published
2016
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41. Association between inflammation biomarkers, anatomic extent of deep venous thrombosis, and venous symptoms after deep venous thrombosis

Author

Anderson, David R., Chagnon, Isabelle, Demers, Christine, Desmarais, Sylvie, Ginsberg, Jeffrey S., Hanmiah, Rajendar, Kaatz, Scott, Kassis, Jeannine, Kearon, Clive, Kovacs, Michael J., Lazo-Langner, Alexander, Miron, Marie-José, Opatrny, Lucie, Ortel, Thomas L., Rathbun, Suman, Rodger, Marc A., Schulman, Sam, Selby, Rita, Smith, Reginald, Solymoss, Susan, Tagalakis, Vicky, Wells, Philip S., Wong, Turnly, Yeo, Erik, Rabinovich, Anat, Cohen, Jacqueline M., Cushman, Mary, and Kahn, Susan R.

Published
2015
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44. The risk of major bleeding in patients with Factor V Leiden or Prothrombin G20210A gene mutation while on extended anticoagulant treatment for VTE

Author

Caiano, Lucia, primary, Kovacs, Michael J., additional, Lazo-Langner, Alejandro, additional, Anderson, David R., additional, Kahn, Susan R., additional, Shah, Vinay, additional, Kaatz, Scott, additional, Zide, Russell S., additional, Schulman, Sam, additional, Chagnon, Isabelle, additional, Mallick, Ranjeeta, additional, Rodger, Marc A., additional, and Wells, Philip S., additional

Published
2022
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45. Redefining clinical venous thromboembolism phenotypes: a novel approach using latent class analysis

Author

de Winter, Maria A., primary, Uijl, Alicia, additional, Büller, Harry R., additional, Carrier, Marc, additional, Cohen, Alexander T., additional, Hansen, John-Bjarne, additional, Kaasjager, Karin (H.A.H.), additional, Kakkar, Lord Ajay K., additional, Middeldorp, Saskia, additional, Raskob, Gary E., additional, Sørensen, Henrik Toft, additional, Wells, Philip S., additional, Nijkeuter, Mathilde, additional, and Dorresteijn, Jannick A.N., additional

Published
2022
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47. Performance of D-Dimers in Patients with Prior History of Venous Thromboembolism Based on Anticoagulation Status

Author

Mai, Vicky, primary, Martens, Emily S.L., additional, Righini, Marc, additional, Schulman, Sam, additional, Thiruganasambandamoorthy, Venkatesh, additional, Kahn, Susan, additional, Bates, Veronica, additional, Pecarskie, Amanda, additional, Kovacs, Michael J., additional, Visser, Shaun, additional, Shivakumar, Sudeep P, additional, Tan, Melanie, additional, Rodger, Marc A., additional, Scarvelis, Dimitrios, additional, Delluc, Aurelien, additional, Girard, Philippe, additional, Huisman, Menno V, additional, Wells, Philip S., additional, Klok, Frederikus A, additional, and Le Gal, Gregoire, additional

Published
2022
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50. Antepartum dalteparin versus no antepartum dalteparin for the prevention of pregnancy complications in pregnant women with thrombophilia (TIPPS): a multinational open-label randomised trial

Author

Rodger, Marc A, Hague, William M, Kingdom, John, Kahn, Susan R, Karovitch, Alan, Sermer, Mathew, Clement, Anne Marie, Coat, Suzette, Chan, Wee Shian, Said, Joanne, Rey, Evelyne, Robinson, Sue, Khurana, Rshmi, Demers, Christine, Kovacs, Michael J, Solymoss, Susan, Hinshaw, Kim, Dwyer, James, Smith, Graeme, McDonald, Sarah, Newstead-Angel, Jill, McLeod, Anne, Khandelwal, Meena, Silver, Robert M, Le Gal, Gregoire, Greer, Ian A, Keely, Erin, Rosene-Montella, Karen, Walker, Mark, and Wells, Philip S

Published
2014
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