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5. Synchronous versus metachronous spinal metastasis: a comparative study of survival outcomes following neurosurgical treatment

Author

Banat, Mohammed, Potthoff, Anna-Laura, Hamed, Motaz, Borger, Valeri, Scorzin, Jasmin E., Lampmann, Tim, Asoglu, Harun, Khalafov, Logman, Schmeel, Frederic C., Paech, Daniel, Radbruch, Alexander, Nitsch, Louisa, Weller, Johannes, Herrlinger, Ulrich, Toma, Marieta, Gielen, Gerrit H., Vatter, Hartmut, and Schneider, Matthias

Published
2024
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7. Endovascular thrombectomy for acute ischaemic stroke with established large infarct (TENSION): 12-month outcomes of a multicentre, open-label, randomised trial

Author

Aamodt, Anne Hege, Adamczewski, Olaf, Alektoror, Kirill, Alexander, März, Alexandrou, Maria, Alias, Quentin, Al-Kuzae, Fadha Elawi, Allard, Julien, Al-Schameri, Rahman, Álvarez, Alberto, Andersen, Grethe, AnkerlundBlaufeldt, Rolf, Antje, Riedel, Appelbohm, Hannes, Argren, Maria, Assmann, Anne, Augustin, Michael, Bach, Elke, Bar, Michal, Barleben, Maria, Baronnet, Flore, Barrios, Andrés, Bavúzová, Xénia, BayThomsen, Rikke, Becker, Sandra, Beer, Sylvia, Behme, Daniel, Bellut, Maximilian, Bendszus, Martin, Berkefeld, Joachim, Bester, Maximillian, Bode, Felix J., Boehme, Christian, Boese, Ramona, Bohmann, Ferdinand, Bonekamp, Susanne, Borggrefe, Jan, Boss, Erendira Gabriela, Boutchakova, Maria, Boxhammer, Elfi, Brandhofe, Annemarie, Breckwoldt, Michael, Brekenfeld, Casper, Brehm, Alex, Brem, Christian, Breuer, Stella, Breyer, Tobias, Brodová, Petra, Broocks, Gabriel, Brosinski, Christoph, Bubel, Nele, Búřil, Jiří, Čábal, Martin, Casado, Laura, de Celis, Elena, Chabert, Emmanuel, Charisse, Daniel, Cheng, Bastian, Chovanec, Vendelín, Cidlinsky, Peter, Cisár, Juraj, Clarençon, Fréderic, Crozier, Sophie, Čurdová, Nina, Damaskinos, Michele, Damgaard, Dorte, Daniš, Martin, Dazinger, Florian, Deb-Chatterji, Milani, Delalic, Asima, Delekta, Agnieszka, Delorme, Stephen, Deutschmann, Hannes, Diamandis, Elie, Diedrichsen, Tove, Doležalová, Irena, Dorn, Franziska, du Mesnil de Rochemont, Richard, DupontHougaard, Kristina, Ebrahimi, Taraneh, Eff, Florian, Eliášová, Ilona, Enriquez, Brian, Ergawy, Mostafa, Essig, Fabian, Falkesgaard, Maiken, Fandler-Höfler, Simon, Fernández, Andrés, Ferré, Jean-Christophe, Ferrier, Anna, Fiehler, Jens, Figlewski, Krystian, Fischer, Sebastian, Fischer, Urs, Flottmann, Fabian, Forbrig, Robert, Förch, Christian, Fromm, Annette, Fuentes, Blanca, Gaedke, Ines, Galczak, Romana, Galijasevic, Malik, Ganser, Bernhard, Gattringer, Thomas, Gawlitza, Matthias, Gelhard, Sarah, Gellißen, Susanne, Gerber, Johannes, Giannakakis, Michail Panagiotis, Gindlhuber, Karin, Gizewski, Elke R., Glodny, Bernhard, Godel, Tim, Goebell, Einar, Goldemund, David, Görtler, Michael, Goyal, Mayank, Grams, Astrid E., Gruber, Joachim, Gruber, Katharina, Günthner-Lengsfeld, Thomas, Haase, Kathrin, Hacker-Ivan, Floriana, Hallerstig, Erika, Hametner, Christian, Hanning, Uta, Haring, Jozef, Haršány, Michal, Haršány, Ján, Hartmann, Christian, Hassler, Eva Maria, Hauptmann, Kristina, Haeusler, Karl Georg, Hecker, Constantin, Hellstern, Victoria, Henkes, Hans, Hernández, Victoria, Herweh, Christian, Hilgenfeld, Tim, Hill, Michael D., Hjort, Niels, HjortJensen, Nina, Hoelter, Maya, Hoffmann, Karl-Titus, Holst, Brigitte, Holtmannspoetter, Markus, Hopf-Jensen, Silke, Hoppe, Julia, Horner, Susanne, HougaardSoerensen, Leif, Hua, Vi Tuan, Hubert, Alexander, Hurtíková, Eva, Jakubíček, Stanislava, Janjic, Tanja, Jaramillo, Kirsten, Jedlitschka, Angela, Jensen, Schiela, Jensen, Märit, Jesser, Jessica, Jestaedt, Leonie, Johnson, Sabine, Jonszta, Tomáš, Kalmar, Peter, Karabegovic, Sanja, Karen, Kollo, Kastrup, Andreas, Katja, Hopp, Keeba, Natalia, Keese, Petra, Kefaloykos, Christina, Keil, Fee, Kellert, Lars, Kellinghaus, Christoph, Kestner, Roxane-Isabelle, Kiechl, Stefan, Killer-Oberpfalzer, Monika, Klepanec, Andrej, Knispel, Casjupea, Knoflach, Michael, Kohler, Sabine, Kohlhase, Konstantin, Kollikowski, Alexander Marco, Kovář, Martin, Krajina, Antonín, Kral, Michael, Krastev, Georgi, Krause, Lars Udo, Kreidenhuber, Rudolf, Křivka, Tomáš, Krkoška, Adam, Kröger, Jan Robert, Kronlage, Moritz, Krukowski, Pawel, Kühn, Julia, Kurča, Egon, Kurka, Natalia, Kuschnerow, Michael, Lachmund, Rita, Lamprecht, Susanne, Lange, Rüdiger, Lauer, Monika, de Leciñana, Alonso, Leder, Sara, Leger, Anne, Lehnen, Nils, Lehrieder, Dominik, Leißner, Maximilian, Leitinger, Markus, Leitner, Ursula, Lenck, Stéphanie, Lenzenweger, Eva, Liebig, Thomas, Lowens, Stephan, Lunzer, Manuel, Maegerlein, Christian, Magyar, Marton, Marques, Leonardo, Matyáš, David, Maurer, Gabriele, Mauritz, Matthias, Maximilian, Thormann, Mayer-Süß, Lukas, Meckel, Stephan, Medek, Oldřich, Meissner, Julius N., Mencl, Pavel, Merkle, Andrea, Mesche, Birte, Michalski, Dominik, Mikulík, Robert, Modrau, Boris, Möhlenbruch, Markus A., Mohr, Alexander, Mönninghoff, Christoph, Moser, Tobias, Mücke, Ramona, Müller-Hülsbeck, Stefan, Müller-Thies-Broussalis, Erasmia, Mutzenbach, Sebastian, Navia, Pedro, Neuberger, Ulf, Neugebauer, Hermann, Neumann, Jens, Nguyên, Anh, Niederkorn, Kurt, Nosál', Vladimír, Novobilský, Richard, Ntoulias, Nikos, Nussbaum, Lukas, Oder, Joanna, Oldag, Andreas, Ondrejkovič, Marián, Otto, Ferdinand, Otto, Dagmar, Paech, Daniel, Pagano, Paolo, Pallesen, Lars-Peder, Panský, Michal, Papanagiotou, Panagiotis, Patrick, Samp, Paukisch, Harald, Pelz, Johann, Petersen, Inga, Petersen, Martina, Petzold, Gabor C., Pfaff, Johannes, Pfeilschifter, Waltraud, Pham, Mirko, Pichler, Alexander, Pierot, Laurent, Pikija, Slaven, PlougmannPovlsen, Jan, Polkowski, Christoph, Polomac, Nenad, Portugaller, Rupert Horst, Poulsen, Marika, Preiß, Michael, Premat, Kévin, Prestsæter, Sjur, Prieto-Pérez, Rocio, Psychogios, Marios, Puetz, Volker, Purrucker, Jan, Rai, Heike, Rauch, Maximilian, Raupach, Jan, Reimann, Gernot, Reimann, Georg, Reitz, Sarah, Renc, Ondřej, Retzlaff, Jasmin, Rigual, Ricardo, Ringleb, Peter Arthur, Rivera-Bengoa, Carlota, Rodríguez, Jorge, Rohde, Stefan, Rohler, Siegfried, Rosso, Charlotte, Roth, Christian, Röttcher, Thomas, Roubec, Martin, Roztočilová, Milada, Rudnicka, Svetlana, Ruiz, Gerardo, Ryan, Stephen, Ryckborst, Karla J., Sandvik, Simen, Schäfer, Jan-Hendrik, Schaller-Paule, Martin, Schell, Maximillian, Schellinger, Peter, Schlemm, Eckhard, Schmid, Florian, Schmidt, Christoph, Schmitz, Marie Louise, Schneider, Claus, Scholtz, Jan-Erik, Schönenberger, Silvia, Schröter, Andreas, Schwarz, Daniel, Schwarz, Stephan, Schwarzenhofer, Daniel, Seifert-Held, Thomas, Seiler, Alexander, Seker, Fatih, Shotar, Eimad, Simonsen, Claus Z., Simonsen, Maria Theresa, Sivák, Jozef, Skagen, Karolina, Skjelland, Mona, Šnajdrová, Alena, Solymosi, Lazlo, Sømark, Jesper, Sonnberger, Michael, Soršák, Jakub, Sourour, Nader, Søyland, Jogrim, Spitzer, Daniel, Sporns, Peter, Städt, Michael, Steidl, Eike, Størdal, Anne Margrethe Kaalaas, Stösser, Sebastian, Strickmann, Sarah, Strýček, Ondřej, Suškevič, Igor, Sýkora, Jan, Tennøe, Bjørn, Thaler, Daniela, Theisen, Sara, Thomalla, Götz, Trendafilov, Petar, Trenkler, Johannes, Trumm, Christoph, Tsogkas, Ioannis, Tunold, Jon-Anders, Tveit, Lars, Ulfert, Christian, Vališ, Kateřina, Vaníček, Jiří, Vassilev, Christine, Vítková, Eva, Voit-Höhne, Heinz-Leonhard, Vojtíšek, Bohuslav, Volderauer, Karoline, Vollherbst, Dominik, Vollmuth, Christoph, Volna, Kamila, Volný, Ondřej, VonWeitzel-Mudersbach, Poul, Vorčák, Martin, Wagner, Marlies, Wathle, Gaute Kjellevold, Weber, Werner, Weber, Anushe, Weiss, Viktor, Weller, Johannes M., Wenger-Alakmeh, Katharina, Weyland, Cyrill, Weymayr, Friedrich, Wießpeiner, Ulrike, Willeit, Johannes, Wittwer, Aymeric, Wollenweber, Frank, Wortmann, Ginette, Wunderlich, Silke, Xiong, Yanyan, You, Se-Jong, ZachoSpeiser, Lasse, Zamani, Mahtab, Zelenak, Kamil, Zeleňáková, Jana, Zubel, Seraphine, Subtil, Fabien, Gizewski, Elke R, Hill, Michael D, Krajina, Antonin, Simonsen, Claus Z, Zeleňák, Kamil, Blauenfeldt, Rolf A, Denis, Angélique, Gerber, Johannes C, Keil, Christiane Fee, Mikkelsen, Ronni, Möhlenbruch, Markus, Münnich, Nico, Petzold, Gabor C, Schell, Maximilian, Vollherbst, Dominik F, and Wick, Wolfgang

Published
2024
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9. Undetected pseudoprogressions in the CeTeG/NOA-09 trial: hints from postprogression survival and MRI analyses

Author

Zeyen, Thomas, Paech, Daniel, Weller, Johannes, Schäfer, Niklas, Tzaridis, Theophilos, Duffy, Cathrina, Nitsch, Louisa, Schneider, Matthias, Potthoff, Anna-Laura, Steinbach, Joachim Peter, Hau, Peter, Schlegel, Uwe, Seidel, Clemens, Krex, Dietmar, Grauer, Oliver, Goldbrunner, Roland, Zeiner, Pia Susan, Tabatabai, Ghazaleh, Galldiks, Norbert, Stummer, Walter, Hattingen, Elke, Glas, Martin, Radbruch, Alexander, Herrlinger, Ulrich, and Schaub, Christina

Published
2023
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11. Outcome assessment of intraoperative radiotherapy for brain metastases: results of a prospective observational study with comparative matched-pair analysis

Author

Layer, Julian P., Hamed, Motaz, Potthoff, Anna-Laura, Dejonckheere, Cas S., Layer, Katharina, Sarria, Gustavo R., Scafa, Davide, Koch, David, Köksal, Mümtaz, Kugel, Fabian, Grimmer, Molina, Holz, Jasmin A., Zeyen, Thomas, Friker, Lea L., Borger, Valeri, Schmeel, F. Carsten, Weller, Johannes, Hölzel, Michael, Schäfer, Niklas, Garbe, Stephan, Forstbauer, Helmut, Giordano, Frank A., Herrlinger, Ulrich, Vatter, Hartmut, Schneider, Matthias, and Schmeel, L. Christopher

Published
2023
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12. Outcome of Stroke Patients with Unknown Onset and Unknown Time Last Known Well Undergoing Endovascular Therapy

Author

Stösser, Sebastian, Bode, Felix J., Meissner, Julius N., Weller, Johannes M., Kindler, Christine, Sauer, Malte, Paech, Daniel, Riegler, Christoph, Nolte, Christian H., Pourian, Amitis, Röther, Joachim, Selo, Nadja, Ernemann, Ulrike, Poli, Sven, Eckert, Rosa Marie, Bohner, Georg, Scherling, Korbinian, Dorn, Franziska, and Petzold, Gabor C.

Published
2023
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13. Endovascular thrombectomy for acute ischaemic stroke with established large infarct: multicentre, open-label, randomised trial

Author

Aamodt, Anne Hege, Adamczewski, Olaf, Alektoror, Kirill, Alexander, März, Alexandrou, Maria, Alias, Quentin, Al-Kuzae, Fadha Elawi, Allard, Julien, Al-Schameri, Rahman, Álvarez, Alberto, Andersen, Grethe, AnkerlundBlaufeldt, Rolf, Antje, Riedel, Appelbohm, Hannes, Argren, Maria, Assmann, Anne, Augustin, Michael, Bach, Elke, Bar, Michal, Barleben, Maria, Baronnet, Flore, Barrios, Andrés, Bavúzová, Xénia, BayThomsen, Rikke, Becker, Sandra, Beer, Sylvia, Behme, Daniel, Bellut, Maximilian, Bendszus, Martin, Berkefeld, Joachim, Bester, Maximillian, Bode, Felix J., Boehme, Christian, Boese, Ramona, Bohmann, Ferdinand, Bonekamp, Susanne, Borggrefe, Jan, Boss, Erendira Gabriela, Boutchakova, Maria, Boxhammer, Elfi, Brandhofe, Annemarie, Breckwoldt, Michael, Brekenfeld, Casper, Brehm, Alex, Brem, Christian, Breuer, Stella, Breyer, Tobias, Brodová, Petra, Broocks, Gabriel, Brosinski, Christoph, Bubel, Nele, Búřil, Jiří, Čábal, Martin, Casado, Laura, Celis, Elena de, Chabert, Emmanuel, Charisse, Daniel, Cheng, Bastian, Chovanec, Vendelín, Cidlinsky, Peter, Cisár, Juraj, Clarençon, Fréderic, Crozier, Sophie, Čurdová, Nina, Damaskinos, Michele, Damgaard, Dorte, Daniš, Martin, Dazinger, Florian, Deb-Chatterji, Milani, Delalic, Asima, Delekta, Agnieszka, Delorme, Stephen, Deutschmann, Hannes, Diamandis, Elie, Diedrichsen, Tove, Doležalová, Irena, Dorn, Franziska, du Mesnil de Rochemont, Richard, DupontHougaard, Kristina, Ebrahimi, Taraneh, Eff, Florian, Eliášová, Ilona, Enriquez, Brian, Ergawy, Mostafa, Essig, Fabian, Falkesgaard, Maiken, Fandler-Höfler, Simon, Fernández, Andrés, Ferré, Jean-Christophe, Ferrier, Anna, Fiehler, Jens, Figlewski, Krystian, Fischer, Sebastian, Fischer, Urs, Flottmann, Fabian, Forbig, Robert, Förch, Christian, Fromm, Annette, Fuentes, Blanca, Gaedke, Ines, Galczak, Romana, Galijasevic, Malik, Ganser, Bernhard, Gattringer, Thomas, Gawlitza, Matthias, Gelhard, Sarah, Gellißen, Susanne, Gerber, Johannes, Giannakakis, Michail Panagiotis, Gindlhuber, Karin, Gizewski, Elke R., Glodny, Bernhard, Godel, Tim, Goebell, Einar, Goldemund, David, Görtler, Michael, Goyal, Mayank, Grams, Astrid E., Gruber, Joachim, Gruber, Katharina, Günthner-Lengsfeld, Thomas, Haase, Kathrin, Hacker-Ivan, Floriana, Hallerstig, Erika, Hanning, Uta, Haring, Jozef, Haršány, Michal, Haršány, Ján, Hartmann, Christian, Hassler, Eva Maria, Hauptmann, Kristina, Häusler, Karl Georg, Hecker, Constantin, Hellstern, Victoria, Henkes, Hans, Hernández, Victoria, Herweh, Christian, Hilgenfeld, Tim, Hill, Michael D., Hjort, Niels, HjortJensen, Nina, Hoelter, Maya, Hoffmann, Karl-Titus, Holst, Brigitte, Holtmannspoetter, Markus, Hopf-Jensen, Silke, Hoppe, Julia, Horner, Susanne, HougaardSoerensen, Leif, Hua, Vi Tuan, Hubert, Alexander, Hurtíková, Eva, Jakubíček, Stanislava, Janjic, Tanja, Jaramillo, Kirsten, Jedlitschka, Angela, Jensen, Schiela, Jensen, Märit, Jesser, Jessica, Jestaedt, Leonie, Johnson, Sabine, Jonszta, Tomáš, Kalmar, Peter, Karabegovic, Sanja, Karen, Kollo, Kastrup, Andreas, Katja, Hopp, Keeba, Natalia, Keese, Petra, Kefalaykos, Christina, Keil, Fee, Kellert, Lars, Kellinghaus, Christoph, Kestner, Roxane-Isabelle, Kiechl, Stefan, Killer-Oberpfalzer, Monika, Klepanec, Andrej, Knispel, Casjupea, Knoflach, Michael, Kohler, Sabine, Kohlhase, Konstantin, Kollikowski, Alexander Marco, Kovář, Martin, Krajina, Antonín, Kral, Michael, Krastev, Georgi, Krause, Lars Udo, Kreidenhuber, Rudolf, Křivka, Tomáš, Krkoška, Adam, Kröger, Jan Robert, Kronlage, Moritz, Krukowski, Pawel, Kühn, Julia, Kurča, Egon, Kurka, Natalia, Kuschnerow, Michael, Lachmund, Rita, Lamprecht, Susanne, Lange, Rüdiger, Lauer, Monika, Leciñana, Alonso de, Leder, Sara, Leger, Anne, Lehnen, Nils, Lehrieder, Dominik, Leißner, Maximilian, Leitinger, Markus, Leitner, Ursula, Lenck, Stéphanie, Lenzenweger, Eva, Liebig, Thomas, Lowens, Stephan, Lunzer, Manuel, Maegerlein, Christian, Magyar, Marton, Marques, Leonardo, Matyáš, David, Maurer, Gabriele, Mauritz, Matthias, Maximilian, Thormann, Mayer-Süß, Lukas, Meckel, Stephan, Medek, Oldřich, Meissner, Julius N., Mencl, Pavel, Merkle, Andrea, Mesche, Birte, Michalski, Dominik, Mikulík, Robert, Modrau, Boris, Möhlenbruch, Markus A., Mohr, Alexander, Mönninghoff, Christoph, Moser, Tobias, Mücke, Ramona, Müller-Hülsbeck, Stefan, Müller-Thies-Broussalis, Erasmia, Mutzenbach, Sebastian, Navia, Pedro, Neuberger, Ulf, Neugebauer, Hermann, Neumann, Jens, Nguyên, Anh, Niederkorn, Kurt, Nosál', Vladimír, Novobilský, Richard, Ntoulias, Nikos, Nussbaum, Lukas, Oder, Joanna, Oldag, Andreas, Ondrejkovič, Marián, Otto, Ferdinand, Otto, Dagmar, Paech, Daniel, Pagano, Paolo, Pallesen, Lars-Peder, Panský, Michal, Papanagiotou, Panagiotis, Patrick, Samp, Paukisch, Harald, Pelz, Johann, Petersen, Inga, Petersen, Martina, Petzold, Gabor C., Pfaff, Johannes, Pfeilschifter, Waltraud, Pham, Mirko, Pichler, Alexander, Pierot, Laurent, Pikija, Slaven, PlougmannPovlsen, Jan, Polkowski, Christoph, Polomac, Nenad, Portugaller, Rupert Horst, Poulsen, Marika, Preiß, Michael, Premat, Kévin, Prestsæter, Sjur, Prieto-Pérez, Rocio, Psychogios, Marios, Puetz, Volker, Purrucker, Jan, Rai, Heike, Rauch, Maximilian, Raupach, Jan, Reimann, Gernot, Reimann, Georg, Reitz, Sarah, Renc, Ondřej, Retzlaff, Jasmin, Rigual, Ricardo, Ringleb, Peter Arthur, Rivera-Bengoa, Carlota, Rodríguez, Jorge, Rohde, Stefan, Rohler, Siegfried, Rosso, Charlotte, Roth, Christian, Röttcher, Thomas, Roubec, Martin, Roztočilová, Milada, Rudnicka, Svetlana, Ruiz, Gerardo, Ryan, Stephen, Ryckborst, Karla J., Sandvik, Simen, Schäfer, Jan-Hendrik, Schaller-Paule, Martin, Schell, Maximillian, Schellinger, Peter, Schlemm, Eckhard, Schmid, Florian, Schmidt, Christoph, Schmitz, Marie Louise, Schneider, Claus, Scholtz, Jan-Erik, Schönenberger, Silvia, Schröter, Andreas, Schwarz, Daniel, Schwarz, Stephan, Schwarzenhofer, Daniel, Seifert-Held, Thomas, Seiler, Alexander, Seker, Fatih, Shotar, Eimad, Simonsen, Claus Z., Simonsen, Maria Theresa, Sivák, Jozef, Skagen, Karolina, Skjelland, Mona, Šnajdrová, Alena, Solymosi, Lazlo, Sømark, Jesper, Sonnberger, Michael, Soršák, Jakub, Sourour, Nader, Søyland, Jogrim, Spitzer, Daniel, Sporns, Peter, Städt, Michael, Steidl, Eike, Størdal, Anne Margrethe Kaalaas, Stösser, Sebastian, Strickmann, Sarah, Strýček, Ondřej, Suškevič, Igor, Sýkora, Jan, Tennøe, Bjørn, Thaler, Daniela, Theisen, Sara, Thomalla, Götz, Trendafilov, Petar, Trenkler, Johannes, Trumm, Christoph, Tsogkas, Ioannis, Tunold, Jon-Anders, Tveit, Lars, Ulfert, Christian, Vališ, Kateřina, Vaníček, Jiří, Vassilev, Christine, Vítková, Eva, Voit-Höhne, Heinz-Leonhard, Vojtíšek, Bohuslav, Volderauer, Karoline, Vollherbst, Dominik, Vollmuth, Christoph, Volna, Kamila, Volný, Ondřej, VonWeitzel-Mudersbach, Poul, Vorčák, Martin, Wagner, Marlies, Wathle, Gaute Kjellevold, Weber, Werner, Weber, Anushe, Weiss, Viktor, Weller, Johannes M., Wenger-Alakmeh, Katharina, Weyland, Cyrill, Weymayr, Friedrich, Wießpeiner, Ulrike, Willeit, Johannes, Wittwer, Aymeric, Wollenweber, Frank, Wortmann, Ginette, Wunderlich, Silke, Xiong, Yanyan, You, Se-Jong, ZachoSpeiser, Lasse, Zelenak, Kamil, Zeleňáková, Jana, Zubel, Seraphine, Subtil, Fabien, Gizewski, Elke R, Hill, Michael D, Krajina, Antonin, Simonsen, Claus Z, Zeleňák, Kamil, Blauenfeldt, Rolf A, Denis, Angélique, Gerber, Johannes C, Keil, Christiane Fee, Mikkelsen, Ronni, Möhlenbruch, Markus, Münnich, Nico, Petzold, Gabor C, Schell, Maximilian, Vollherbst, Dominik F, and Wick, Wolfgang

Published
2023
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15. Correction to: Undetected pseudoprogressions in the CeTeG/NOA-09 trial: hints from postprogression survival and MRI analyses

Author

Zeyen, Thomas, Paech, Daniel, Weller, Johannes, Schäfer, Niklas, Tzaridis, Theophilos, Duffy, Cathrina, Nitsch, Louisa, Schneider, Matthias, Potthoff, Anna-Laura, Steinbach, Joachim Peter, Hau, Peter, Schlegel, Uwe, Seidel, Clemens, Krex, Dietmar, Grauer, Oliver, Goldbrunner, Roland, Zeiner, Pia Susan, Tabatabai, Ghazaleh, Galldiks, Norbert, Stummer, Walter, Hattingen, Elke, Glas, Martin, Radbruch, Alexander, Herrlinger, Ulrich, and Schaub, Christina

Published
2023
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16. Prognostic impact of obesity in newly-diagnosed glioblastoma: a secondary analysis of CeTeG/NOA-09 and GLARIUS

Author

Weller, Johannes, Schäfer, Niklas, Schaub, Christina, Potthoff, Anna-Laura, Steinbach, Joachim P., Schlegel, Uwe, Sabel, Michael, Hau, Peter, Seidel, Clemens, Krex, Dietmar, Goldbrunner, Roland, Pietsch, Torsten, Tzaridis, Theophilos, Zeyen, Thomas, Borger, Valeri, Güresir, Erdem, Vatter, Hartmut, Herrlinger, Ulrich, and Schneider, Matthias

Published
2022
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20. Phase I/II trial of meclofenamate in progressive MGMT-methylated glioblastoma under temozolomide second-line therapy—the MecMeth/NOA-24 trial

Author

Zeyen, Thomas, Potthoff, Anna-Laura, Nemeth, Robert, Heiland, Dieter H., Burger, Michael C., Steinbach, Joachim P., Hau, Peter, Tabatabai, Ghazaleh, Glas, Martin, Schlegel, Uwe, Grauer, Oliver, Krex, Dietmar, Schnell, Oliver, Goldbrunner, Roland, Sabel, Michael, Thon, Niklas, Delev, Daniel, Clusmann, Hans, Seidel, Clemens, Güresir, Erdem, Schmid, Matthias, Schuss, Patrick, Giordano, Frank A., Radbruch, Alexander, Becker, Albert, Weller, Johannes, Schaub, Christina, Vatter, Hartmut, Schilling, Judith, Winkler, Frank, Herrlinger, Ulrich, and Schneider, Matthias

Published
2022
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21. Machine learning models for outcome prediction in thrombectomy for large anterior vessel occlusion.

Author

Shirvani, Omid, Warnat‐Herresthal, Stefanie, Savchuk, Ivan, Bode, Felix J., Nitsch, Louisa, Stösser, Sebastian, Ebrahimi, Taraneh, von Danwitz, Niklas, Asperger, Hannah, Layer, Julia, Meissner, Julius, Thielscher, Christian, Dorn, Franziska, Lehnen, Nils, Schultze, Joachim L., Petzold, Gabor C., Weller, Johannes M., Alegiani, Anna, Berrouschot, Jörg, and Boeck‐Behrens, Tobias

Abstract

Objective: Predicting long‐term functional outcomes shortly after a stroke is challenging, even for experienced neurologists. Therefore, we aimed to evaluate multiple machine learning models and the importance of clinical/radiological parameters to develop a model that balances minimal input data with reliable predictions of long‐term functional independency. Methods: Our study utilized data from the German Stroke Registry on patients with large anterior vessel occlusion who underwent endovascular treatment. We trained seven machine learning models using 30 parameters from the first day postadmission to predict a modified Ranking Scale of 0–2 at 90 days poststroke. Model performance was assessed using a 20‐fold cross‐validation and one‐sided Wilcoxon rank‐sum tests. Key features were identified through backward feature selection. Results: We included 7485 individuals with a median age of 75 years and a median NIHSS score at admission of 14 in our analysis. Our Deep Neural Network model demonstrated the best performance among all models including data from 24 h postadmission. Backward feature selection identified the seven most important features to be NIHSS after 24 h, age, modified Ranking Scale after 24 h, premorbid modified Ranking Scale, intracranial hemorrhage within 24 h, intravenous thrombolysis, and NIHSS at admission. Narrowing the Deep Neural Network model's input data to these features preserved the high performance with an AUC of 0.9 (CI: 0.89–0.91). Interpretation: Our Deep Neural Network model, trained on over 7000 patients, predicts 90‐day functional independence using only seven clinical/radiological features from the first day postadmission, demonstrating both high accuracy and practicality for clinical implementation on stroke units. [ABSTRACT FROM AUTHOR]

Published
2024
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22. Clinical significance and prevalence of subarachnoid hyperdensities on flat detector CT after mechanical thrombectomy: does it really matter?

Author

Zidan, Mousa, Shiwa Ghaei, Bode, Felix J., Weller, Johannes M., Krueger, Nadine, Lehnen, Nils Christian, Petzold, Gabor C., Radbruch, Alexander, Dorn, Franziska, and Paech, Daniel

Subjects
NIH Stroke Scale, T-test (Statistics), LOGISTIC regression analysis, KRUSKAL-Wallis Test, BRAIN diseases, TREATMENT effectiveness, DESCRIPTIVE statistics, CHI-squared test, MULTIVARIATE analysis, MANN Whitney U Test, RETROSPECTIVE studies, ODDS ratio, STROKE, THROMBECTOMY, DATA analysis software, CONFIDENCE intervals, DISEASE risk factors, DISEASE complications
Abstract

Background Subarachnoid hyperdensities after mechanical thrombectomy (MT) are a common finding. However, it is often regarded as clinically insignificant. Objective With this single-center investigation, to identify the prevalence of subarachnoid hyperdensities following MT, associated predictors, and the impact on the clinical outcome of the patients. Methods 383 patients from the stroke registry were analyzed for the presence of subarachnoid hyperdensities on flat detector CT (FDCT) directly after the completion of MT, and on follow-up dual-energy CT, then classified according to a visual grading scale. 178 patients were included with anterior circulation occlusions. Regression analysis was performed to identify significant predictors, and Kruskal-Wallis analysis and X² test were performed to test the variables among the different groups. The primary outcome was the modified Rankin Scale (mRS) score at 90 days and was analyzed with the Wilcoxon-Mann-Whitney rank-sum test. Results The prevalence of subarachnoid hyperdensities on FDCT was (66/178, 37.1%) with patients experiencing a significant unfavorable outcome (P=0.035). Significantly fewer patients with subarachnoid hyperdensities achieved a mRS score of ≤3 at 90 days 25/66 (37.9%) vs 60/1 12 (53.6%), P=0.043). In addition, mortality was significantly higher in the subarachnoid hyperdensities group (34.8% vs 19.6%, P=0.024). Distal occlusions and a higher number of device passes were significantly associated with subarachnoid hyperdensities (P=0.026) and (P=0.001), respectively. Patients who received intravenous tissue plasminogen activator had significantly fewer subarachnoid hyperdensities (P=0.029). Conclusions Postinterventional subarachnoid hyperdensities are a frequent finding after MT and are associated with neurological decline and worse functional outcome. They are more common with distal occlusions and multiple device passes. [ABSTRACT FROM AUTHOR]

Published
2024
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23. Tumor-associated epilepsy in patients with brain metastases: necrosis-to-tumor ratio forecasts postoperative seizure freedom

Author

Bahna, Majd, Heimann, Muriel, Bode, Christian, Borger, Valeri, Eichhorn, Lars, Güresir, Erdem, Hamed, Motaz, Herrlinger, Ulrich, Ko, Yon-Dschun, Lehmann, Felix, Potthoff, Anna-Laura, Radbruch, Alexander, Schaub, Christina, Surges, Rainer, Weller, Johannes, Vatter, Hartmut, Schäfer, Niklas, Schneider, Matthias, and Schuss, Patrick

Published
2022
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25. Synchronous versus metachronous spinal metastasis: a comparative study of survival outcomes following neurosurgical treatment

Author

Banat, Mohammed, primary, Potthoff, Anna-Laura, additional, Hamed, Motaz, additional, Borger, Valeri, additional, Scorzin, Jasmin E., additional, Lampmann, Tim, additional, Asoglu, Harun, additional, Khalafov, Logman, additional, Schmeel, Frederic C., additional, Paech, Daniel, additional, Radbruch, Alexander, additional, Nitsch, Louisa, additional, Weller, Johannes, additional, Herrlinger, Ulrich, additional, Toma, Marieta, additional, Gielen, Gerrit, additional, Vatter, Hartmut, additional, and Schneider, Matthias, additional

Published
2024
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28. Tumour Treating Fields (TTFields) in combination with lomustine and temozolomide in patients with newly diagnosed glioblastoma

Author

Lazaridis, Lazaros, Schäfer, Niklas, Teuber-Hanselmann, Sarah, Blau, Tobias, Schmidt, Teresa, Oster, Christoph, Weller, Johannes, Tzaridis, Theophilos, Pierscianek, Daniela, Keyvani, Kathy, Kleinschnitz, Christoph, Stuschke, Martin, Scheffler, Björn, Deuschl, Cornelius, Sure, Ulrich, Herrlinger, Ulrich, Kebir, Sied, and Glas, Martin

Published
2020
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29. Health-related quality of life and neurocognitive functioning with lomustine–temozolomide versus temozolomide in patients with newly diagnosed, MGMT-methylated glioblastoma (CeTeG/NOA-09): a randomised, multicentre, open-label, phase 3 trial

Author

Weller, Johannes, Tzaridis, Theophilos, Mack, Frederic, Steinbach, Joachim Peter, Schlegel, Uwe, Hau, Peter, Krex, Dietmar, Grauer, Oliver, Goldbrunner, Roland, Bähr, Oliver, Uhl, Martin, Seidel, Clemens, Tabatabai, Ghazaleh, Brehmer, Stefanie, Bullinger, Lars, Galldiks, Norbert, Schaub, Christina, Kebir, Sied, Stummer, Walter, Simon, Matthias, Fimmers, Rolf, Coch, Christoph, Glas, Martin, Herrlinger, Ulrich, and Schäfer, Niklas

Published
2019
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31. Endovascular treatment of cerebral sinus thrombosis due to vaccine-induced immune thrombotic thrombocytopenia.

Author

Weller, Johannes, Krzywicka, Katarzyna, van de Munckhof, Anita, Dorn, Franziska, Althaus, Katharina, Bode, Felix J, Bandettini di Poggio, Monica, Buck, Brian, Kleinig, Timothy, Cordonnier, Charlotte, Dizonno, Vanessa, Duan, Jiangang, Elkady, Ahmed, Chew, Beng Lim Alvin, Garcia-Esperon, Carlos, Field, Thalia S, Legault, Catherine, Morin Martin, Mar, Michalski, Dominik, and Pelz, Johann

Published
2024
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34. Endovascular thrombectomy for acute ischaemic stroke with established large infarct: multicentre, open-label, randomised trial

Author

Bendszus, Martin, primary, Fiehler, Jens, additional, Subtil, Fabien, additional, Bonekamp, Susanne, additional, Aamodt, Anne Hege, additional, Fuentes, Blanca, additional, Gizewski, Elke R, additional, Hill, Michael D, additional, Krajina, Antonin, additional, Pierot, Laurent, additional, Simonsen, Claus Z, additional, Zeleňák, Kamil, additional, Blauenfeldt, Rolf A, additional, Cheng, Bastian, additional, Denis, Angélique, additional, Deutschmann, Hannes, additional, Dorn, Franziska, additional, Flottmann, Fabian, additional, Gellißen, Susanne, additional, Gerber, Johannes C, additional, Goyal, Mayank, additional, Haring, Jozef, additional, Herweh, Christian, additional, Hopf-Jensen, Silke, additional, Hua, Vi Tuan, additional, Jensen, Märit, additional, Kastrup, Andreas, additional, Keil, Christiane Fee, additional, Klepanec, Andrej, additional, Kurča, Egon, additional, Mikkelsen, Ronni, additional, Möhlenbruch, Markus, additional, Müller-Hülsbeck, Stefan, additional, Münnich, Nico, additional, Pagano, Paolo, additional, Papanagiotou, Panagiotis, additional, Petzold, Gabor C, additional, Pham, Mirko, additional, Puetz, Volker, additional, Raupach, Jan, additional, Reimann, Gernot, additional, Ringleb, Peter Arthur, additional, Schell, Maximilian, additional, Schlemm, Eckhard, additional, Schönenberger, Silvia, additional, Tennøe, Bjørn, additional, Ulfert, Christian, additional, Vališ, Kateřina, additional, Vítková, Eva, additional, Vollherbst, Dominik F, additional, Wick, Wolfgang, additional, Thomalla, Götz, additional, Adamczewski, Olaf, additional, Alektoror, Kirill, additional, Alexander, März, additional, Alexandrou, Maria, additional, Alias, Quentin, additional, Al-Kuzae, Fadha Elawi, additional, Allard, Julien, additional, Al-Schameri, Rahman, additional, Álvarez, Alberto, additional, Andersen, Grethe, additional, AnkerlundBlaufeldt, Rolf, additional, Antje, Riedel, additional, Appelbohm, Hannes, additional, Argren, Maria, additional, Assmann, Anne, additional, Augustin, Michael, additional, Bach, Elke, additional, Bar, Michal, additional, Barleben, Maria, additional, Baronnet, Flore, additional, Barrios, Andrés, additional, Bavúzová, Xénia, additional, BayThomsen, Rikke, additional, Becker, Sandra, additional, Beer, Sylvia, additional, Behme, Daniel, additional, Bellut, Maximilian, additional, Bendszus, Martin, additional, Berkefeld, Joachim, additional, Bester, Maximillian, additional, Bode, Felix J., additional, Boehme, Christian, additional, Boese, Ramona, additional, Bohmann, Ferdinand, additional, Borggrefe, Jan, additional, Boss, Erendira Gabriela, additional, Boutchakova, Maria, additional, Boxhammer, Elfi, additional, Brandhofe, Annemarie, additional, Breckwoldt, Michael, additional, Brekenfeld, Casper, additional, Brehm, Alex, additional, Brem, Christian, additional, Breuer, Stella, additional, Breyer, Tobias, additional, Brodová, Petra, additional, Broocks, Gabriel, additional, Brosinski, Christoph, additional, Bubel, Nele, additional, Búřil, Jiří, additional, Čábal, Martin, additional, Casado, Laura, additional, Celis, Elena de, additional, Chabert, Emmanuel, additional, Charisse, Daniel, additional, Chovanec, Vendelín, additional, Cidlinsky, Peter, additional, Cisár, Juraj, additional, Clarençon, Fréderic, additional, Crozier, Sophie, additional, Čurdová, Nina, additional, Damaskinos, Michele, additional, Damgaard, Dorte, additional, Daniš, Martin, additional, Dazinger, Florian, additional, Deb-Chatterji, Milani, additional, Delalic, Asima, additional, Delekta, Agnieszka, additional, Delorme, Stephen, additional, Diamandis, Elie, additional, Diedrichsen, Tove, additional, Doležalová, Irena, additional, du Mesnil de Rochemont, Richard, additional, DupontHougaard, Kristina, additional, Ebrahimi, Taraneh, additional, Eff, Florian, additional, Eliášová, Ilona, additional, Enriquez, Brian, additional, Ergawy, Mostafa, additional, Essig, Fabian, additional, Falkesgaard, Maiken, additional, Fandler-Höfler, Simon, additional, Fernández, Andrés, additional, Ferré, Jean-Christophe, additional, Ferrier, Anna, additional, Figlewski, Krystian, additional, Fischer, Sebastian, additional, Fischer, Urs, additional, Forbig, Robert, additional, Förch, Christian, additional, Fromm, Annette, additional, Gaedke, Ines, additional, Galczak, Romana, additional, Galijasevic, Malik, additional, Ganser, Bernhard, additional, Gattringer, Thomas, additional, Gawlitza, Matthias, additional, Gelhard, Sarah, additional, Gerber, Johannes, additional, Giannakakis, Michail Panagiotis, additional, Gindlhuber, Karin, additional, Gizewski, Elke R., additional, Glodny, Bernhard, additional, Godel, Tim, additional, Goebell, Einar, additional, Goldemund, David, additional, Görtler, Michael, additional, Grams, Astrid E., additional, Gruber, Joachim, additional, Gruber, Katharina, additional, Günthner-Lengsfeld, Thomas, additional, Haase, Kathrin, additional, Hacker-Ivan, Floriana, additional, Hallerstig, Erika, additional, Hanning, Uta, additional, Haršány, Michal, additional, Haršány, Ján, additional, Hartmann, Christian, additional, Hassler, Eva Maria, additional, Hauptmann, Kristina, additional, Häusler, Karl Georg, additional, Hecker, Constantin, additional, Hellstern, Victoria, additional, Henkes, Hans, additional, Hernández, Victoria, additional, Hilgenfeld, Tim, additional, Hill, Michael D., additional, Hjort, Niels, additional, HjortJensen, Nina, additional, Hoelter, Maya, additional, Hoffmann, Karl-Titus, additional, Holst, Brigitte, additional, Holtmannspoetter, Markus, additional, Hoppe, Julia, additional, Horner, Susanne, additional, HougaardSoerensen, Leif, additional, Hubert, Alexander, additional, Hurtíková, Eva, additional, Jakubíček, Stanislava, additional, Janjic, Tanja, additional, Jaramillo, Kirsten, additional, Jedlitschka, Angela, additional, Jensen, Schiela, additional, Jesser, Jessica, additional, Jestaedt, Leonie, additional, Johnson, Sabine, additional, Jonszta, Tomáš, additional, Kalmar, Peter, additional, Karabegovic, Sanja, additional, Karen, Kollo, additional, Katja, Hopp, additional, Keeba, Natalia, additional, Keese, Petra, additional, Kefalaykos, Christina, additional, Keil, Fee, additional, Kellert, Lars, additional, Kellinghaus, Christoph, additional, Kestner, Roxane-Isabelle, additional, Kiechl, Stefan, additional, Killer-Oberpfalzer, Monika, additional, Knispel, Casjupea, additional, Knoflach, Michael, additional, Kohler, Sabine, additional, Kohlhase, Konstantin, additional, Kollikowski, Alexander Marco, additional, Kovář, Martin, additional, Krajina, Antonín, additional, Kral, Michael, additional, Krastev, Georgi, additional, Krause, Lars Udo, additional, Kreidenhuber, Rudolf, additional, Křivka, Tomáš, additional, Krkoška, Adam, additional, Kröger, Jan Robert, additional, Kronlage, Moritz, additional, Krukowski, Pawel, additional, Kühn, Julia, additional, Kurka, Natalia, additional, Kuschnerow, Michael, additional, Lachmund, Rita, additional, Lamprecht, Susanne, additional, Lange, Rüdiger, additional, Lauer, Monika, additional, Leciñana, Alonso de, additional, Leder, Sara, additional, Leger, Anne, additional, Lehnen, Nils, additional, Lehrieder, Dominik, additional, Leißner, Maximilian, additional, Leitinger, Markus, additional, Leitner, Ursula, additional, Lenck, Stéphanie, additional, Lenzenweger, Eva, additional, Liebig, Thomas, additional, Lowens, Stephan, additional, Lunzer, Manuel, additional, Maegerlein, Christian, additional, Magyar, Marton, additional, Marques, Leonardo, additional, Matyáš, David, additional, Maurer, Gabriele, additional, Mauritz, Matthias, additional, Maximilian, Thormann, additional, Mayer-Süß, Lukas, additional, Meckel, Stephan, additional, Medek, Oldřich, additional, Meissner, Julius N., additional, Mencl, Pavel, additional, Merkle, Andrea, additional, Mesche, Birte, additional, Michalski, Dominik, additional, Mikulík, Robert, additional, Modrau, Boris, additional, Möhlenbruch, Markus A., additional, Mohr, Alexander, additional, Mönninghoff, Christoph, additional, Moser, Tobias, additional, Mücke, Ramona, additional, Müller-Thies-Broussalis, Erasmia, additional, Mutzenbach, Sebastian, additional, Navia, Pedro, additional, Neuberger, Ulf, additional, Neugebauer, Hermann, additional, Neumann, Jens, additional, Nguyên, Anh, additional, Niederkorn, Kurt, additional, Nosál', Vladimír, additional, Novobilský, Richard, additional, Ntoulias, Nikos, additional, Nussbaum, Lukas, additional, Oder, Joanna, additional, Oldag, Andreas, additional, Ondrejkovič, Marián, additional, Otto, Ferdinand, additional, Otto, Dagmar, additional, Paech, Daniel, additional, Pallesen, Lars-Peder, additional, Panský, Michal, additional, Patrick, Samp, additional, Paukisch, Harald, additional, Pelz, Johann, additional, Petersen, Inga, additional, Petersen, Martina, additional, Petzold, Gabor C., additional, Pfaff, Johannes, additional, Pfeilschifter, Waltraud, additional, Pichler, Alexander, additional, Pikija, Slaven, additional, PlougmannPovlsen, Jan, additional, Polkowski, Christoph, additional, Polomac, Nenad, additional, Portugaller, Rupert Horst, additional, Poulsen, Marika, additional, Preiß, Michael, additional, Premat, Kévin, additional, Prestsæter, Sjur, additional, Prieto-Pérez, Rocio, additional, Psychogios, Marios, additional, Purrucker, Jan, additional, Rai, Heike, additional, Rauch, Maximilian, additional, Reimann, Georg, additional, Reitz, Sarah, additional, Renc, Ondřej, additional, Retzlaff, Jasmin, additional, Rigual, Ricardo, additional, Rivera-Bengoa, Carlota, additional, Rodríguez, Jorge, additional, Rohde, Stefan, additional, Rohler, Siegfried, additional, Rosso, Charlotte, additional, Roth, Christian, additional, Röttcher, Thomas, additional, Roubec, Martin, additional, Roztočilová, Milada, additional, Rudnicka, Svetlana, additional, Ruiz, Gerardo, additional, Ryan, Stephen, additional, Ryckborst, Karla J., additional, Sandvik, Simen, additional, Schäfer, Jan-Hendrik, additional, Schaller-Paule, Martin, additional, Schell, Maximillian, additional, Schellinger, Peter, additional, Schmid, Florian, additional, Schmidt, Christoph, additional, Schmitz, Marie Louise, additional, Schneider, Claus, additional, Scholtz, Jan-Erik, additional, Schröter, Andreas, additional, Schwarz, Daniel, additional, Schwarz, Stephan, additional, Schwarzenhofer, Daniel, additional, Seifert-Held, Thomas, additional, Seiler, Alexander, additional, Seker, Fatih, additional, Shotar, Eimad, additional, Simonsen, Claus Z., additional, Simonsen, Maria Theresa, additional, Sivák, Jozef, additional, Skagen, Karolina, additional, Skjelland, Mona, additional, Šnajdrová, Alena, additional, Solymosi, Lazlo, additional, Sømark, Jesper, additional, Sonnberger, Michael, additional, Soršák, Jakub, additional, Sourour, Nader, additional, Søyland, Jogrim, additional, Spitzer, Daniel, additional, Sporns, Peter, additional, Städt, Michael, additional, Steidl, Eike, additional, Størdal, Anne Margrethe Kaalaas, additional, Stösser, Sebastian, additional, Strickmann, Sarah, additional, Strýček, Ondřej, additional, Suškevič, Igor, additional, Sýkora, Jan, additional, Thaler, Daniela, additional, Theisen, Sara, additional, Trendafilov, Petar, additional, Trenkler, Johannes, additional, Trumm, Christoph, additional, Tsogkas, Ioannis, additional, Tunold, Jon-Anders, additional, Tveit, Lars, additional, Vaníček, Jiří, additional, Vassilev, Christine, additional, Voit-Höhne, Heinz-Leonhard, additional, Vojtíšek, Bohuslav, additional, Volderauer, Karoline, additional, Vollherbst, Dominik, additional, Vollmuth, Christoph, additional, Volna, Kamila, additional, Volný, Ondřej, additional, VonWeitzel-Mudersbach, Poul, additional, Vorčák, Martin, additional, Wagner, Marlies, additional, Wathle, Gaute Kjellevold, additional, Weber, Werner, additional, Weber, Anushe, additional, Weiss, Viktor, additional, Weller, Johannes M., additional, Wenger-Alakmeh, Katharina, additional, Weyland, Cyrill, additional, Weymayr, Friedrich, additional, Wießpeiner, Ulrike, additional, Willeit, Johannes, additional, Wittwer, Aymeric, additional, Wollenweber, Frank, additional, Wortmann, Ginette, additional, Wunderlich, Silke, additional, Xiong, Yanyan, additional, You, Se-Jong, additional, ZachoSpeiser, Lasse, additional, Zelenak, Kamil, additional, Zeleňáková, Jana, additional, and Zubel, Seraphine, additional

Published
2023
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35. Endovascular treatment of cerebral sinus thrombosis due to vaccine-induced immune thrombotic thrombocytopenia

Author

Weller, Johannes, primary, Krzywicka, Katarzyna, additional, van de Munckhof, Anita, additional, Dorn, Franziska, additional, Althaus, Katharina, additional, Bode, Felix J, additional, Bandettini di Poggio, Monica, additional, Buck, Brian, additional, Kleinig, Timothy, additional, Cordonnier, Charlotte, additional, Dizonno, Vanessa, additional, Duan, Jiangang, additional, Elkady, Ahmed, additional, Chew, Beng Lim Alvin, additional, Garcia-Esperon, Carlos, additional, Field, Thalia S, additional, Legault, Catherine, additional, Morin Martin, Mar, additional, Michalski, Dominik, additional, Pelz, Johann, additional, Schoenenberger, Silvia, additional, Nagel, Simon, additional, Petruzzellis, Marco, additional, Raposo, Nicolas, additional, Skjelland, Mona, additional, Zimatore, Domenico Sergio, additional, Aaron, Sanjith, additional, Sanchez van Kammen, Mayte, additional, Aguiar de Sousa, Diana, additional, Lindgren, Erik, additional, Jood, Katarina, additional, Scutelnic, Adrian, additional, Heldner, Mirjam R, additional, Poli, Sven, additional, Arauz, Antonio, additional, Conforto, Adriana B, additional, Putaala, Jukka, additional, Tatlisumak, Turgut, additional, Arnold, Marcel, additional, Coutinho, Jonathan M, additional, Günther, Albrecht, additional, Zimmermann, Julian, additional, and Ferro, José M, additional

Published
2023
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37. Baseline T1 hyperintense and diffusion-restricted lesions are not linked to prolonged survival in bevacizumab-treated glioblastoma patients of the GLARIUS trial

Author

Kebir, Sied, Schaub, Christina, Junold, Nina, Hattingen, Elke, Schäfer, Niklas, Steinbach, Joachim P., Weyerbrock, Astrid, Hau, Peter, Goldbrunner, Roland, Galldiks, Norbert, Weller, Johannes, Mack, Frederic, Tzaridis, Theophilos, Bähr, Oliver, Seidel, Clemens, Schlegel, Uwe, Schmidt-Graf, Friederike, Rohde, Veit, Borchers, Christian, Tabatabai, Ghazaleh, Hänel, Mathias, Sabel, Michael, Gerlach, Rüdiger, Krex, Dietmar, Belka, Claus, Vatter, Hartmut, Proescholdt, Martin, Glas, Martin, and Herrlinger, Ulrich

Published
2019
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40. COVID-19 Is an Independent Risk Factor for Detrimental Invasive Fungal Disease in Patients on Veno-Venous Extracorporeal Membrane Oxygenation: A Retrospective Study

Author

Poth, Jens Martin, primary, Schewe, Jens-Christian, additional, Lehmann, Felix, additional, Weller, Johannes, additional, Schmandt, Mathias Willem, additional, Kreyer, Stefan, additional, Muenster, Stefan, additional, Putensen, Christian, additional, and Ehrentraut, Stefan Felix, additional

Published
2023
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41. Additive prognostic impact of the cerebrospinal fluid arginine/ornithine ratio to established clinical scores in aneurysmal subarachnoid hemorrhage

Author

Weller, Johannes, primary, Lampmann, Tim, additional, Asoglu, Harun, additional, Schneider, Matthias, additional, Ehrentraut, Stefan Felix, additional, Lehmann, Felix, additional, Güresir, Erdem, additional, Dorn, Franziska, additional, Petzold, Gabor C., additional, Vatter, Hartmut, additional, and Zimmermann, Julian, additional

Published
2023
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43. Supplemental Figure 1 from Diagnosis of Pseudoprogression Following Lomustine–Temozolomide Chemoradiation in Newly Diagnosed Glioblastoma Patients Using FET-PET

Author

Werner, Jan-Michael, primary, Weller, Johannes, primary, Ceccon, Garry, primary, Schaub, Christina, primary, Tscherpel, Caroline, primary, Lohmann, Philipp, primary, Bauer, Elena K., primary, Schäfer, Niklas, primary, Stoffels, Gabriele, primary, Baues, Christian, primary, Celik, Eren, primary, Marnitz, Simone, primary, Kabbasch, Christoph, primary, Gielen, Gerrit H., primary, Fink, Gereon R., primary, Langen, Karl-Josef, primary, Herrlinger, Ulrich, primary, and Galldiks, Norbert, primary

Published
2023
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44. Targeted anticonvulsive treatment of IDH-wildtype glioblastoma based on DNA methylation subclasses

Author

Drexler, Richard, primary, Göttsche, Jennifer, additional, Sauvigny, Thomas, additional, Schüller, Ulrich, additional, Khatri, Robin, additional, Hausmann, Fabian, additional, Hänzelmann, Sonja, additional, Huber, Tobias B, additional, Bonn, Stefan, additional, Heiland, Dieter H, additional, Delev, Daniel, additional, Venkataramani, Varun, additional, Winkler, Frank, additional, Weller, Johannes, additional, Zeyen, Thomas, additional, Herrlinger, Ulrich, additional, Gempt, Jens, additional, Ricklefs, Franz L, additional, and Dührsen, Lasse, additional

Published
2023
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45. A novel serum extracellular vesicle protein signature to monitor glioblastoma tumor progression

Author

Tzaridis, Theophilos, Weller, Johannes, Bachurski, Daniel, Shakeri, Farhad, Schaub, Christina, Hau, Peter, Buness, Andreas, Schlegel, Uwe, Steinbach, Joachim-Peter, Seidel, Clemens, Goldbrunner, Roland, Schaefer, Niklas, Wechsler-Reya, Robert J., Hallek, Michael, Scheffler, Bjoern, Glas, Martin, Haeberle, Lothar, Herrlinger, Ulrich, Coch, Christoph, Reiners, Katrin S., Hartmann, Gunther, Tzaridis, Theophilos, Weller, Johannes, Bachurski, Daniel, Shakeri, Farhad, Schaub, Christina, Hau, Peter, Buness, Andreas, Schlegel, Uwe, Steinbach, Joachim-Peter, Seidel, Clemens, Goldbrunner, Roland, Schaefer, Niklas, Wechsler-Reya, Robert J., Hallek, Michael, Scheffler, Bjoern, Glas, Martin, Haeberle, Lothar, Herrlinger, Ulrich, Coch, Christoph, Reiners, Katrin S., and Hartmann, Gunther

Abstract

Detection of tumor progression in patients with glioblastoma remains a major challenge. Extracellular vesicles (EVs) are potential biomarkers and can be detected in the blood of patients with glioblastoma. In our study, we evaluated the potential of serum-derived EVs from glioblastoma patients to serve as biomarker for tumor progression. EVs from serum of glioblastoma patients and healthy volunteers were separated by size exclusion chromatography and ultracentrifugation. EV markers were defined by using a proximity-extension assay and bead-based flow cytometry. Tumor progression was defined according to modified RANO criteria. EVs from the serum of glioblastoma patients (n = 67) showed an upregulation of CD29, CD44, CD81, CD146, C1QA and histone H3 as compared to serum EVs from healthy volunteers (P value range: <.0001 to .08). For two independent cohorts of glioblastoma patients, we noted upregulation of C1QA, CD44 and histone H3 upon tumor progression, but not in patients with stable disease. In a multivariable logistic regression analysis, a combination of CD29, CD44, CD81, C1QA and histone H3 correlated with RANO-defined tumor progression with an AUC of 0.76. Measurement of CD29, CD44, CD81, C1QA and histone H3 in serum-derived EVs of glioblastoma patients, along with standard MRI assessment, has the potential to improve detection of true tumor progression and thus could be a useful biomarker for clinical decision making.

Published
2023

46. Intravenous thrombolysis upon flow restoration improves outcome in endovascular thrombectomy.

Author

Weller, Johannes M., Dorn, Franziska, Petzold, Gabor C., and Bode, Felix J.

Subjects
INTRAVENOUS therapy, CONFIDENCE intervals, ISCHEMIC stroke, THROMBOLYTIC therapy, MANN Whitney U Test, FISHER exact test, TREATMENT effectiveness, T-test (Statistics), THROMBECTOMY, BLOOD circulation, ENDOVASCULAR surgery, ODDS ratio, LOGISTIC regression analysis, LONGITUDINAL method, TISSUE plasminogen activator
Abstract

Background We hypothesized that ongoing IV thrombolysis (IVT) at flow restoration in patients with acute ischemic stroke (AIS) treated with IVT and endovascular thrombectomy (ET) is associated with improved outcome. Methods We included patients with IVT and successful recanalization (modified Thrombolysis in Cerebral Infarction score ≥2b) after ET from an observational multicenter cohort, the German Stroke Registry -- Endovascular Treatment trial. Procedural characteristics and functional outcome at discharge and 90 days were compared between patients with and without ongoing IVT at flow restoration. To determine associations with functional outcome, adjusted ORs were calculated using ordinal multivariable logistic regression models adjusted for potential baseline confounder variables. Results Among 1303 patients treated with IVT and ET who achieved successful recanalization, IVT was ongoing in 13.8% (n=180) at flow restoration. Ongoing IVT was associated with better functional outcome at discharge (adjusted OR 1.61; 95% CI 1.13 to 2.30) and at 90 days (adjusted OR 1.52; 95% CI 1.06 to 2.18). Conclusion These results provide preliminary evidence for a benefit of ongoing IVT at flow restoration in patients with AIS treated with ET. [ABSTRACT FROM AUTHOR]

Published
2023
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47. NIMG-32. POSTPROGRESSION SURVIVAL AND MRI FEATURES AT PROGRESSION IN MGMT-METHYLATED GLIOBLASTOMA FOLLOWING TEMOZOLOMIDE (TMZ) OR CCNU/TMZ THERAPY - AN ANALYSIS OF THE CETEG/NOA-09-TRIAL

Author

Zeyen, Thomas, primary, Paech, Daniel, additional, Weller, Johannes, additional, Schäfer, Niklas, additional, Tzaridis, Theophilos, additional, Duffy, Cathrina, additional, Nitsch, Louisa, additional, Schneider, Matthias, additional, Steinbach, Joachim, additional, Hau, Peter, additional, Schlegel, Uwe, additional, Seidel, Clemens, additional, Krex, Dietmar, additional, Grauer, Oliver, additional, Goldbrunner, Roland, additional, Zeiner, Pia, additional, Tabatabai, Ghazaleh, additional, Galldiks, Norbert, additional, Stummer, Walter, additional, Hattingen, Elke, additional, Glas, Martin, additional, Radbruch, Alexander, additional, Herrlinger, Ulrich, additional, and Schaub, Christina, additional

Published
2022
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48. CTNI-07. LOMUSTINE/TEMOZOLOMIDE CHEMOTHERAPY FOR NEWLY DIAGNOSED MGMT-METHYLATED IDHWT GLIOBLASTOMA ACCORDING TO CETEG/NOA-09: REAL-WORLD EXPERIENCE IN A MULTICENTER COHORT

Author

Weller, Johannes, primary, Zeyen, Thomas, additional, Schlegel, Uwe, additional, Lazaridis, Lazaros, additional, Werner, Jan-Michael, additional, Onken, Julia, additional, Zeiner, Pia, additional, Drexler, Richard, additional, Hau, Peter, additional, Seidel, Clemens, additional, Grosse, Lucia, additional, Clusmann, Hans, additional, Sabel, Michael, additional, Ringel, Florian, additional, Pichler, Josef, additional, Grauer, Oliver, additional, Hundsberger, Thomas, additional, Schnell, Oliver, additional, Mair, Maximilian J, additional, Uhl, Martin, additional, Schmidt-Graf, Friederike, additional, Glas, Martin, additional, Galldiks, Norbert, additional, Unteroberdörster, Meike, additional, Steinbach, Joachim, additional, Ricklefs, Franz, additional, Renovanz, Mirjam, additional, Delev, Daniel Ivanov, additional, Turgut, Merih O, additional, Flesch, Oliver R, additional, Cipriani, Debora, additional, Preusser, Matthias, additional, Kebir, Sied, additional, Misch, Martin, additional, Goldbrunner, Roland, additional, Westphal, Manfred, additional, Tabatabai, Ghazaleh, additional, Schäfer, Niklas, additional, Schneider, Matthias, additional, Vatter, Hartmut, additional, Giordano, Frank, additional, Schaub, Christina, additional, and Herrlinger, Ulrich, additional

Published
2022
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