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8 results on '"Weinbrom, Sarah"'

1. Correction Notice: Isolation of Epithelial and Stromal Cells from Colon Tissues in Homeostasis and Under Inflammatory Conditions

Author

Morral, Clara, primary, Ghinnagow, Reem, additional, Karakasheva, Tatiana, additional, Zhou, Yusen, additional, Thadi, Anusha, additional, Li, Ning, additional, Yoshor, Benjamin, additional, Soto, Gloria, additional, Chen, Chia-, additional, Aleynick, Daniel, additional, Weinbrom, Sarah, additional, Fulton, MaryKate, additional, Uzun, Yasin, additional, Bewtra, Meenakshi, additional, Kelsen, Judith, additional, Tan, Kai, additional, Minn, Andy, additional, and Hamilton, Kathryn, additional

Published
2024
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2. Clinicopathologic Characterization of Lymphocytic Colitis in the Pediatric Population.

Author

González, Iván A., Conrad, Maire, Weinbrom, Sarah, Patel, Trusha, Kelsen, Judith R., and Russo, Pierre

Abstract

Background: Lymphocytic colitis (LC) in the pediatric population has been associated with immune dysregulation. Methods: Single-center retrospective study of pediatric LC. Results: 50 patients (35 female, 70%) with a median age of 12 years at diagnosis (interquartile range: 5.7–15.8) of LC were identified. At presentation, 11 patients (22%) had malnutrition, 16 (32%) had a known underlying immune dysregulation, 4 (8%) had celiac disease (CD), and none had a diagnosis of inflammatory bowel disease. The most common medications prior to diagnosis were non-steroidal anti-inflammatory drugs, proton pump inhibitor, and selective serotonin reuptake inhibitors (10% each). Colonic biopsies showed a median number of intraepithelial lymphocytes (IELs)/100 epithelial cells of 48 (range: 25–85), and only 10% of cases had neutrophilic cryptitis. Upper gastrointestinal tract findings included lymphocytic esophagitis (4%), and duodenal IELs without and with villous blunting (9% each) (n: 47). Ten patients (23%) had increased IELs in the terminal ileum (n: 43). Treatments including 5-ASA, budesonide, prednisone, and gluten-free diet improved symptoms in <50% of patients (n: 42), and all follow-up colonoscopies showed persistent LC (n: 13). Conclusion: Our study supports the association of LC with immune-mediated conditions, most commonly celiac disease. Symptomatic improvement was seen in <50% of patients with none of the patients with repeat colonoscopy showing histologic improvement. [ABSTRACT FROM AUTHOR]

Published
2024
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3. Isolation of Epithelial and Stromal Cells from Colon Tissues in Homeostasis and Under Inflammatory Conditions

Author

Morral, Clara, primary, Ghinnagow, Reem, additional, Karakasheva, Tatiana, additional, Zhou, Yusen, additional, Thadi, Anusha, additional, Li, Ning, additional, Yoshor, Benjamin, additional, Soto, Gloria, additional, Chen, Chia-, additional, Aleynick, Daniel, additional, Weinbrom, Sarah, additional, Fulton, MaryKate, additional, Uzun, Yasin, additional, Bewtra, Meenakshi, additional, Kelsen, Judith, additional, Lengner, Chris, additional, Tan, Kai, additional, Minn, Andy, additional, and Hamilton, Kathryn, additional

Published
2023
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6. Single cell RNA sequencing of a biopsy specimen v1

Author

Karakasheva, Tatiana, primary, not provided Thadi, Anusha, additional, not provided Li, Ning, additional, not provided Uzun, Yasin, additional, not provided Chen, Chia-Hui, additional, not provided Aleynick, Daniel, additional, not provided Shraim, Rawan, additional, not provided Weinbrom, Sarah, additional, not provided Soto, Gloria, additional, not provided Kelsen, Judith, additional, not provided Lengner, Chris, additional, Tan, Kai, additional, and E Hamilton, Kathryn, additional

Published
2021
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