48 results on '"Weibin Gu"'
Search Results
2. Adverse Outcomes Associated With Higher Mean Blood Pressure and Greater Blood Pressure Variability Immediately After Successful Embolectomy in Those With Acute Ischemic Stroke, and the Influence of Pretreatment Collateral Circulation Status
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Dacheng Liu, Ximing Nie, Yuesong Pan, Hongyi Yan, Yuehua Pu, Yufei Wei, Yuan Cai, Yarong Ding, Qixuan Lu, Zhe Zhang, Weibin Gu, Xinyi Hou, Zhonghua Yang, Miao Wen, Penglian Wang, Gaoting Ma, Ning Ma, Zhongrong Miao, Xinyi Leng, Bernard Yan, Stephen M. Davis, Yongjun Wang, and Liping Liu more...
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blood pressure ,blood pressure variability ,collateral ,endovascular treatment ,outcome ,Diseases of the circulatory (Cardiovascular) system ,RC666-701 - Abstract
Background To investigate whether collateral status could modify the associations between post‐thrombectomy blood pressure (BP) measures and outcomes. Methods and Results Patients with anterior‐circulation large‐vessel‐occlusion successfully recanalized in a multicenter endovascular thrombectomy registry were enrolled. Pretreatment collateral status was graded and dichotomized (good/poor) in angiography. Maximum, minimum, and mean systolic BP (SBP) and BP variability (assessed by the SD, coefficient of variation) during the initial 24 hours after endovascular thrombectomy were obtained. The primary outcome was unfavorable 90‐day outcome (modified Rankin Scale score 3–6). Secondary outcomes included symptomatic intracranial hemorrhage and 90‐day mortality. Adjusted odds ratios (aOR) of BP parameters over the outcomes were obtained in all patients and in patients with good/poor collaterals. Among 596 patients (mean age 66 years; 59.9% males), 302 (50.7%) patients had unfavorable 90‐day outcome. In multivariable analyses, higher mean SBP (aOR, 1.59 per 10 mm Hg increment; 95% CI, 1.26–2.02; P140 mm Hg (versus ≤120 mm Hg; aOR, 4.27; 95% CI, 1.66–10.97; P=0.002), and higher SBP SD (aOR, 1.08 per 1‐SD increment; 95% CI, 1.01–1.16; P=0.02) were respectively associated with unfavorable 90‐day outcome in patients with poor collateral but not in those with good collateral. A marginal interaction between SBP coefficient of variation tertiles and collaterals on 90‐day functional outcome (P for interaction, 0.09) was observed. A significant interaction between SBP coefficient of variation tertiles and collaterals on 90‐day mortality (P for interaction, 0.03) was observed. Conclusions Higher postprocedural BP is associated with 90‐day unfavorable outcomes after successful endovascular thrombectomy in patients with poor collateral. Registration URL: https://www.chictr.org.cn; Unique identifier: ChiCTR1900022154. more...
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- 2021
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3. Cerebral Hemodynamic Changes After Endovascular Recanalization of Symptomatic Chronic Intracranial Artery Occlusion
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Kaijiang Kang, Bo Yang, Xiping Gong, Xing Chen, Weibin Gu, Guofeng Ma, Zhongrong Miao, Xingquan Zhao, and Ning Ma
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stroke ,intracranial occlusion ,recanalization ,hemodynamics ,CT perfusion ,Neurology. Diseases of the nervous system ,RC346-429 - Abstract
Objective: We performed this study to evaluate the hemodynamic changes over time after successful endovascular recanalization in patients with symptomatic chronic intracranial artery occlusion (CIAO).Materials and Methods: We included 20 patients with symptomatic CIAO in a high-volume stroke center from June 2014 to June 2019. All subjects were evaluated with CT perfusion (CTP) studies before and after the recanalization. The relative cerebral blood flows (rCBFs) in perforating artery territory (PAT) and cortical artery territory (CAT) of occluded arteries were compared before and after the recanalization. The patients were categorized into subgroups based on the time interval from revascularization to post-procedural CTP, occlusion sites, and restenosis status. The proportion of rCBF change (rCBFc%) was compared in variable subgroups.Results: The rCBF increased significantly from 0.52 to 0.71 in PAT (P < 0.001) and from 0.59 to 0.85 in CAT (P < 0.001) after recanalization, and there were also statistical differences in variable subgroups except for those with restenosis. The median and interquartile range (IQR) of rCBFc% were 35.2 and 18.6–56.6%. For patients with short-term follow-up (55.2%), the rCBFc% was relatively higher than that in patients with mid-term (35.4%) and long-term follow-up (32.7%), although without statistical difference (P = 0.273). For patients with restenosis, the rCBFc% was significantly lower than that in patients without restenosis (18.5 vs. 37.3%, P = 0.008).Conclusions: In patients with symptomatic CIAO, the CBF may increase and be relatively stable over time after successful recanalization except for restenosis. more...
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- 2020
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4. Cerebral Hemodynamic Changes After Revascularization in Patients With Hemorrhagic Moyamoya Disease
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Kaijiang Kang, Ning Ma, Jinxin Li, Yuan Shen, Weibin Gu, Guofeng Ma, Dong Zhang, and Xingquan Zhao
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hemodynamics ,intracranial hemorrhage ,moyamoya disease ,perfusion ,revascularization ,Neurology. Diseases of the nervous system ,RC346-429 - Abstract
Objective: To explore the cerebral hemodynamic changes after revascularization in patients with hemorrhagic moyamoya disease (MMD).Materials and Methods: We retrospectively included 57 hemorrhagic MMD patients in a high-volume stroke center from January 2016 to December 2018. All subjects were evaluated with whole-brain CT perfusion (CTP) before and after surgical revascularization. Absolute and relative CTP values in the regions of cortical middle cerebral artery territory (CMT) and deep brain area (DBA) of hemorrhagic hemispheres were measured. Differences between pre- and post-operative CTP values were assessed comprehensively. The patients were categorized into subgroups based on revascularization subtypes and postoperative CTP intervals.Results: The relative cerebral blood volume (rCBV) in DBA and CMT significantly reduced in postoperative CTP (P < 0.05). The median and interquartile range of the proportion of rCBV decrease (rCBVc%) were 7.2% (2.3–13.2%). The rCBV reduction retained statistical significant in patients who received subtypes of revascularization, and in patients with variable intervals of follow-up (P < 0.05). There was no significant difference of rCBVc% between patients who received different revascularization and among patients with different postoperative CTP intervals (P > 0.05). The relative mean transit time (rMTT) and relative time to peak (rTTP) also showed downward trends, but without retainable statistical significance in stratified analysis. There was no significant change in relative cerebral blood flow (rCBF) (P > 0.05).Conclusion: In patients with hemorrhagic MMD, the CBV appeared to decrease and be relatively stable in the chronic phase after revascularization, with varying degrees of MTT and TTP shortening. However, there was no significant change in CBF. more...
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- 2020
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5. The database of the PREDICTS (Projecting Responses of Ecological Diversity In Changing Terrestrial Systems) project
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Lawrence N. Hudson, Tim Newbold, Sara Contu, Samantha L. L. Hill, Igor Lysenko, Adriana De Palma, Helen R. P. Phillips, Tamera I. Alhusseini, Felicity E. Bedford, Dominic J. Bennett, Hollie Booth, Victoria J. Burton, Charlotte W. T. Chng, Argyrios Choimes, David L. P. Correia, Julie Day, Susy Echeverría‐Londoño, Susan R. Emerson, Di Gao, Morgan Garon, Michelle L. K. Harrison, Daniel J. Ingram, Martin Jung, Victoria Kemp, Lucinda Kirkpatrick, Callum D. Martin, Yuan Pan, Gwilym D. Pask‐Hale, Edwin L. Pynegar, Alexandra N. Robinson, Katia Sanchez‐Ortiz, Rebecca A. Senior, Benno I. Simmons, Hannah J. White, Hanbin Zhang, Job Aben, Stefan Abrahamczyk, Gilbert B. Adum, Virginia Aguilar‐Barquero, Marcelo A. Aizen, Belén Albertos, E. L. Alcala, Maria delMar Alguacil, Audrey Alignier, Marc Ancrenaz, Alan N. Andersen, Enrique Arbeláez‐Cortés, Inge Armbrecht, Víctor Arroyo‐Rodríguez, Tom Aumann, Jan C. Axmacher, Badrul Azhar, Adrián B. Azpiroz, Lander Baeten, Adama Bakayoko, András Báldi, John E. Banks, Sharad K. Baral, Jos Barlow, Barbara I. P. Barratt, Lurdes Barrico, Paola Bartolommei, Diane M. Barton, Yves Basset, Péter Batáry, Adam J. Bates, Bruno Baur, Erin M. Bayne, Pedro Beja, Suzan Benedick, Åke Berg, Henry Bernard, Nicholas J. Berry, Dinesh Bhatt, Jake E. Bicknell, Jochen H. Bihn, Robin J. Blake, Kadiri S. Bobo, Roberto Bóçon, Teun Boekhout, Katrin Böhning‐Gaese, Kevin J. Bonham, Paulo A. V. Borges, Sérgio H. Borges, Céline Boutin, Jérémy Bouyer, Cibele Bragagnolo, Jodi S. Brandt, Francis Q. Brearley, Isabel Brito, Vicenç Bros, Jörg Brunet, Grzegorz Buczkowski, Christopher M. Buddle, Rob Bugter, Erika Buscardo, Jörn Buse, Jimmy Cabra‐García, Nilton C. Cáceres, Nicolette L. Cagle, María Calviño‐Cancela, Sydney A. Cameron, Eliana M. Cancello, Rut Caparrós, Pedro Cardoso, Dan Carpenter, Tiago F. Carrijo, Anelena L. Carvalho, Camila R. Cassano, Helena Castro, Alejandro A. Castro‐Luna, Cerda B. Rolando, Alexis Cerezo, Kim Alan Chapman, Matthieu Chauvat, Morten Christensen, Francis M. Clarke, Daniel F.R. Cleary, Giorgio Colombo, Stuart P. Connop, Michael D. Craig, Leopoldo Cruz‐López, Saul A. Cunningham, Biagio D'Aniello, Neil D'Cruze, Pedro Giovâni daSilva, Martin Dallimer, Emmanuel Danquah, Ben Darvill, Jens Dauber, Adrian L. V. Davis, Jeff Dawson, Claudio deSassi, Benoit deThoisy, Olivier Deheuvels, Alain Dejean, Jean‐Louis Devineau, Tim Diekötter, Jignasu V. Dolia, Erwin Domínguez, Yamileth Dominguez‐Haydar, Silvia Dorn, Isabel Draper, Niels Dreber, Bertrand Dumont, Simon G. Dures, Mats Dynesius, Lars Edenius, Paul Eggleton, Felix Eigenbrod, Zoltán Elek, Martin H. Entling, Karen J. Esler, Ricardo F. deLima, Aisyah Faruk, Nina Farwig, Tom M. Fayle, Antonio Felicioli, Annika M. Felton, Roderick J. Fensham, Ignacio C. Fernandez, Catarina C. Ferreira, Gentile F. Ficetola, Cristina Fiera, Bruno K. C. Filgueiras, Hüseyin K. Fırıncıoğlu, David Flaspohler, Andreas Floren, Steven J. Fonte, Anne Fournier, Robert E. Fowler, Markus Franzén, Lauchlan H. Fraser, Gabriella M. Fredriksson, Geraldo B. Freire Jr, Tiago L. M. Frizzo, Daisuke Fukuda, Dario Furlani, René Gaigher, Jörg U. Ganzhorn, Karla P. García, Juan C. Garcia‐R, Jenni G. Garden, Ricardo Garilleti, Bao‐Ming Ge, Benoit Gendreau‐Berthiaume, Philippa J. Gerard, Carla Gheler‐Costa, Benjamin Gilbert, Paolo Giordani, Simonetta Giordano, Carly Golodets, Laurens G. L. Gomes, Rachelle K. Gould, Dave Goulson, Aaron D. Gove, Laurent Granjon, Ingo Grass, Claudia L. Gray, James Grogan, Weibin Gu, Moisès Guardiola, Nihara R. Gunawardene, Alvaro G. Gutierrez, Doris L. Gutiérrez‐Lamus, Daniela H. Haarmeyer, Mick E. Hanley, Thor Hanson, Nor R. Hashim, Shombe N. Hassan, Richard G. Hatfield, Joseph E. Hawes, Matt W. Hayward, Christian Hébert, Alvin J. Helden, John‐André Henden, Philipp Henschel, Lionel Hernández, James P. Herrera, Farina Herrmann, Felix Herzog, Diego Higuera‐Diaz, Branko Hilje, Hubert Höfer, Anke Hoffmann, Finbarr G. Horgan, Elisabeth Hornung, Roland Horváth, Kristoffer Hylander, Paola Isaacs‐Cubides, Hiroaki Ishida, Masahiro Ishitani, Carmen T. Jacobs, Víctor J. Jaramillo, Birgit Jauker, F. Jiménez Hernández, McKenzie F. Johnson, Virat Jolli, Mats Jonsell, S. Nur Juliani, Thomas S. Jung, Vena Kapoor, Heike Kappes, Vassiliki Kati, Eric Katovai, Klaus Kellner, Michael Kessler, Kathryn R. Kirby, Andrew M. Kittle, Mairi E. Knight, Eva Knop, Florian Kohler, Matti Koivula, Annette Kolb, Mouhamadou Kone, Ádám Kőrösi, Jochen Krauss, Ajith Kumar, Raman Kumar, David J. Kurz, Alex S. Kutt, Thibault Lachat, Victoria Lantschner, Francisco Lara, Jesse R. Lasky, Steven C. Latta, William F. Laurance, Patrick Lavelle, Violette Le Féon, Gretchen LeBuhn, Jean‐Philippe Légaré, Valérie Lehouck, María V. Lencinas, Pia E. Lentini, Susan G. Letcher, Qi Li, Simon A. Litchwark, Nick A. Littlewood, Yunhui Liu, Nancy Lo‐Man‐Hung, Carlos A. López‐Quintero, Mounir Louhaichi, Gabor L. Lövei, Manuel Esteban Lucas‐Borja, Victor H. Luja, Matthew S. Luskin, M Cristina MacSwiney G, Kaoru Maeto, Tibor Magura, Neil Aldrin Mallari, Louise A. Malone, Patrick K. Malonza, Jagoba Malumbres‐Olarte, Salvador Mandujano, Inger E. Måren, Erika Marin‐Spiotta, Charles J. Marsh, E. J. P. Marshall, Eliana Martínez, Guillermo Martínez Pastur, David Moreno Mateos, Margaret M. Mayfield, Vicente Mazimpaka, Jennifer L. McCarthy, Kyle P. McCarthy, Quinn S. McFrederick, Sean McNamara, Nagore G. Medina, Rafael Medina, Jose L. Mena, Estefania Mico, Grzegorz Mikusinski, Jeffrey C. Milder, James R. Miller, Daniel R. Miranda‐Esquivel, Melinda L. Moir, Carolina L. Morales, Mary N. Muchane, Muchai Muchane, Sonja Mudri‐Stojnic, A. Nur Munira, Antonio Muoñz‐Alonso, B. F. Munyekenye, Robin Naidoo, A. Naithani, Michiko Nakagawa, Akihiro Nakamura, Yoshihiro Nakashima, Shoji Naoe, Guiomar Nates‐Parra, Dario A. Navarrete Gutierrez, Luis Navarro‐Iriarte, Paul K. Ndang'ang'a, Eike L. Neuschulz, Jacqueline T. Ngai, Violaine Nicolas, Sven G. Nilsson, Norbertas Noreika, Olivia Norfolk, Jorge Ari Noriega, David A. Norton, Nicole M. Nöske, A. Justin Nowakowski, Catherine Numa, Niall O'Dea, Patrick J. O'Farrell, William Oduro, Sabine Oertli, Caleb Ofori‐Boateng, Christopher Omamoke Oke, Vicencio Oostra, Lynne M. Osgathorpe, Samuel Eduardo Otavo, Navendu V. Page, Juan Paritsis, Alejandro Parra‐H, Luke Parry, Guy Pe'er, Peter B. Pearman, Nicolás Pelegrin, Raphaël Pélissier, Carlos A. Peres, Pablo L. Peri, Anna S. Persson, Theodora Petanidou, Marcell K. Peters, Rohan S. Pethiyagoda, Ben Phalan, T. Keith Philips, Finn C. Pillsbury, Jimmy Pincheira‐Ulbrich, Eduardo Pineda, Joan Pino, Jaime Pizarro‐Araya, A. J. Plumptre, Santiago L. Poggio, Natalia Politi, Pere Pons, Katja Poveda, Eileen F. Power, Steven J. Presley, Vânia Proença, Marino Quaranta, Carolina Quintero, Romina Rader, B. R. Ramesh, Martha P. Ramirez‐Pinilla, Jai Ranganathan, Claus Rasmussen, Nicola A. Redpath‐Downing, J. Leighton Reid, Yana T. Reis, José M. Rey Benayas, Juan Carlos Rey‐Velasco, Chevonne Reynolds, Danilo Bandini Ribeiro, Miriam H. Richards, Barbara A. Richardson, Michael J. Richardson, Rodrigo Macip Ríos, Richard Robinson, Carolina A. Robles, Jörg Römbke, Luz Piedad Romero‐Duque, Matthias Rös, Loreta Rosselli, Stephen J. Rossiter, Dana S. Roth, T'ai H. Roulston, Laurent Rousseau, André V. Rubio, Jean‐Claude Ruel, Jonathan P. Sadler, Szabolcs Sáfián, Romeo A. Saldaña‐Vázquez, Katerina Sam, Ulrika Samnegård, Joana Santana, Xavier Santos, Jade Savage, Nancy A. Schellhorn, Menno Schilthuizen, Ute Schmiedel, Christine B. Schmitt, Nicole L. Schon, Christof Schüepp, Katharina Schumann, Oliver Schweiger, Dawn M. Scott, Kenneth A. Scott, Jodi L. Sedlock, Steven S. Seefeldt, Ghazala Shahabuddin, Graeme Shannon, Douglas Sheil, Frederick H. Sheldon, Eyal Shochat, Stefan J. Siebert, Fernando A. B. Silva, Javier A. Simonetti, Eleanor M. Slade, Jo Smith, Allan H. Smith‐Pardo, Navjot S. Sodhi, Eduardo J. Somarriba, Ramón A. Sosa, Grimaldo Soto Quiroga, Martin‐Hugues St‐Laurent, Brian M. Starzomski, Constanti Stefanescu, Ingolf Steffan‐Dewenter, Philip C. Stouffer, Jane C. Stout, Ayron M. Strauch, Matthew J. Struebig, Zhimin Su, Marcela Suarez‐Rubio, Shinji Sugiura, Keith S. Summerville, Yik‐Hei Sung, Hari Sutrisno, Jens‐Christian Svenning, Tiit Teder, Caragh G. Threlfall, Anu Tiitsaar, Jacqui H. Todd, Rebecca K. Tonietto, Ignasi Torre, Béla Tóthmérész, Teja Tscharntke, Edgar C. Turner, Jason M. Tylianakis, Marcio Uehara‐Prado, Nicolas Urbina‐Cardona, Denis Vallan, Adam J. Vanbergen, Heraldo L. Vasconcelos, Kiril Vassilev, Hans A. F. Verboven, Maria João Verdasca, José R. Verdú, Carlos H. Vergara, Pablo M. Vergara, Jort Verhulst, Massimiliano Virgilio, Lien Van Vu, Edward M. Waite, Tony R. Walker, Hua‐Feng Wang, Yanping Wang, James I. Watling, Britta Weller, Konstans Wells, Catrin Westphal, Edward D. Wiafe, Christopher D. Williams, Michael R. Willig, John C. Z. Woinarski, Jan H. D. Wolf, Volkmar Wolters, Ben A. Woodcock, Jihua Wu, Joseph M. Wunderle Jr, Yuichi Yamaura, Satoko Yoshikura, Douglas W. Yu, Andrey S. Zaitsev, Juliane Zeidler, Fasheng Zou, Ben Collen, Rob M. Ewers, Georgina M. Mace, Drew W. Purves, Jörn P. W. Scharlemann, and Andy Purvis more...
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data sharing ,global biodiversity modeling ,global change ,habitat destruction ,land use ,Ecology ,QH540-549.5 - Abstract
Abstract The PREDICTS project—Projecting Responses of Ecological Diversity In Changing Terrestrial Systems (https://www.nhm.ac.uk/our-science/our-work/biodiversity/predicts.html)—has collated from published studies a large, reasonably representative database of comparable samples of biodiversity from multiple sites that differ in the nature or intensity of human impacts relating to land use. We have used this evidence base to develop global and regional statistical models of how local biodiversity responds to these measures. We describe and make freely available this 2016 release of the database, containing more than 3.2 million records sampled at over 26,000 locations and representing over 47,000 species. We outline how the database can help in answering a range of questions in ecology and conservation biology. To our knowledge, this is the largest and most geographically and taxonomically representative database of spatial comparisons of biodiversity that has been collated to date; it will be useful to researchers and international efforts wishing to model and understand the global status of biodiversity. more...
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- 2017
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6. Association Between Cerebral Hypoperfusion and Cognitive Impairment in Patients With Chronic Vertebra-Basilar Stenosis
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Yiming Deng, Luyao Wang, Xuan Sun, Lian Liu, Meifang Zhu, Chunxue Wang, Binbin Sui, Mi Shen, Weibin Gu, Dapeng Mo, Ning Ma, Ligang Song, Xiaoqing Li, Xiaochuan Huo, Zhongrong Miao, Duanduan Chen, and Feng Gao more...
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vertebra-basilar stenosis ,cognitive impairment ,cerebral hypoperfusion ,cerebral infarction ,stroke ,Psychiatry ,RC435-571 - Abstract
Objective: This study aimed to investigate the association between cognitive impairment and cerebral haemodynamic changes in patients with chronic vertebra-basilar (VB) stenosis.Methods: Patients with severe posterior circulation VB stenosis and infarction or a history of infarction for more than 2 weeks from January 2014 to January 2015 were enrolled (n = 96). They were divided into three groups, namely, the computed tomography perfusion (CTP) normal group, the CTP compensated group, and the CTP decompensated group. Cognitive function was assessed using a validated Chinese version of the Mini-Mental State Examination (MMSE), the Frontal Assessment Battery (FAB), and the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS). Regression models were used to identify independent risk factors for cognitive impairment.Results: The MMSE and FAB scores of patients in the CTP decompensated group were significantly lower than those of patients in the CTP normal and CTP compensated groups (all p < 0.05). The RBANS total and its domain scores, including immediate memory, visual acuity, and delayed memory, in the CTP compensated and CTP decompensated groups were significantly lower than those in the CTP normal group (all p < 0.05). Multiple regression analyses showed that CTP compensation, CTP decompensation, severe VB tandem stenosis, and multiple infarctions were independent risk factors for cognitive impairment.Conclusions: Low perfusion caused by severe VB stenosis can lead to extensive cognitive impairments in areas such as immediate memory, visual span, and delayed memory. more...
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- 2018
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7. Fully automatic identification of post-treatment infarct lesions after endovascular therapy based on non-contrast computed tomography.
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Ximing Nie, Xiran Liu, Hao Yang, Feng Shi, Weibin Gu, Xinyi Hou, Yufei Wei, Qixuan Lu, Haiwei Bai, Jiaping Chen, Tianhang Liu, Hongyi Yan, Zhonghua Yang, Miao Wen, Yuesong Pan, Chao Huang 0002, Long Wang 0015, and Liping Liu more...
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- 2023
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8. Physics-informed Neural Network for Quadrotor Dynamical Modeling.
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Weibin Gu, Stefano Primatesta, and Alessandro Rizzo
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- 2024
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9. An Integrated Control Architecture for a Cloud-based Unmanned Aerial Vehicle System with Lossy Networks.
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Weibin Gu, Carlos Perez-Montenegro, Elisa Capello, and Alessandro Rizzo
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- 2019
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10. UAV Model-based Flight Control with Artificial Neural Networks: A Survey.
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Weibin Gu, Kimon P. Valavanis, Matthew J. Rutherford, and Alessandro Rizzo
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- 2020
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11. Prediction of futile recanalisation after endovascular treatment in acute ischaemic stroke: development and validation of a hybrid machine learning model
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Liping Liu, Zhongrong Miao, Zixiao Li, Dongdong Liu, Xia Meng, Tao Liu, Yong Jiang, Yuesong Pan, Jiaping Chen, Weibin Gu, Hongyi Yan, Yufei Wei, Zhonghua Yang, Jian Cheng, Ximing Nie, Miao Wen, Zhenzhou Wu, Guoyang Gong, Jinxu Yang, Xinxin Li, Tianming Zhan, and Xiran Liu more...
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Neurology. Diseases of the nervous system ,RC346-429 - Abstract
Background Identification of futile recanalisation following endovascular therapy (EVT) in patients with acute ischaemic stroke is both crucial and challenging. Here, we present a novel risk stratification system based on hybrid machine learning method for predicting futile recanalisation.Methods Hybrid machine learning models were developed to address six clinical scenarios within the EVT and perioperative management workflow. These models were trained on a prospective database using hybrid feature selection technique to predict futile recanalisation following EVT. The optimal model was validated and compared with existing models and scoring systems in a multicentre prospective cohort to develop a hybrid machine learning-based risk stratification system for futile recanalisation prediction.Results Using a hybrid feature selection approach, we trained and tested multiple classifiers on two independent patient cohorts (n=1122) to develop a hybrid machine learning-based prediction model. The model demonstrated superior discriminative ability compared with other models and scoring systems (area under the curve=0.80, 95% CI 0.73 to 0.87) and was transformed into a web application (RESCUE-FR Index) that provides a risk stratification system for individual prediction (accessible online at fr-index.biomind.cn/RESCUE-FR/).Conclusions The proposed hybrid machine learning approach could be used as an individualised risk prediction model to facilitate adherence to clinical practice guidelines and shared decision-making for optimal candidate selection and prognosis assessment in patients undergoing EVT. more...
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12. High-Resolution Magnetic Resonance Imaging in Endovascular Treatment of Vertebrobasilar Junction Stenosis.
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Rui Huang, Feng Gao, Dapeng Mo, Ming Yang, Zhikai Hou, Yifan Liu, Rongrong Cui, Kaijiang Kang, Weibin Gu, Zhongrong Miao, and Ning Ma
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- 2023
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13. Migratory enhancement in brain MRI of rosette-forming glioneuronal tumour over 11 years
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Bin Chen, Huiyuan Chen, Huanguang Liu, Weibin Gu, and Zaiqiang Zhang
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Neurology (clinical) ,General Medicine - Published
- 2022
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14. Exploring diagnostic performance of T2 mapping in diffuse glioma grading
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Xin-Yi Hou, Ding Ma, Shiyuan Fang, Shaowu Li, and Weibin Gu
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Receiver operating characteristic ,business.industry ,WHO Grade II Glioma ,T2 mapping ,medicine.disease ,Diffuse Glioma ,Glioma grading ,T2 relaxation ,Glioma ,Medicine ,Original Article ,Radiology, Nuclear Medicine and imaging ,business ,Nuclear medicine ,Grading (tumors) - Abstract
Background To evaluate the diagnostic performance of T2 mapping in differentiating WHO grade II glioma from high-grade glioma (HGG). Methods We conducted a single-center, retrospective diagnostic study. Confirmed diffuse glioma (WHO grade II-IV) patients who underwent post-contrast T1-weighted imaging, T2-weighted imaging, and T2 mapping were included. All diagnoses were based on histological and molecular tests. Seventy-five percent of cases were subsampled to generate receiver operating characteristic (ROC) curves and areas under the curve (AUC), while the remaining cases were used to test the accuracy of T2 mapping. Subsampling was repeated four times. Age, T2 relaxation time, and contrast-enhancement status were used to generate a multivariable ROC curve. T2 relaxation time was also used to generate ROC curves to predict the isocitrate dehydrogenase (IDH) status. Results A total of 159 patients were included in the study. After four repeats of subsampling, the AUCs of the T2 mapping ROC curve were 0.801 (95% CI: 0.724-0.879), 0.795 (95% CI: 0.714-0.875), 0.803 (95% CI: 0.723-0.884), and 0.801 (95% CI: 0.716-0.886), with an average sensitivity of 0.753 and an average specificity of 0.767. When applied to the remaining 25% of cases, the accuracy was 75%, 93.75%, 82.50%, and 71.74%. The AUC of the multivariable ROC was 0.927 (95% CI: 0.882-0.971). IDH-mutant and IDH-wildtype gliomas have significantly different T2 relaxation times (146.28 and 124.10 ms, respectively; P=0.001), and the AUC of IDH-mutant prediction was 0.687 (95% CI: 0.585-0.789). Conclusions Quantitative T2 mapping differentiated WHO grade II glioma from HGG with moderate sensitivity and specificity. Given the advantages of short acquisition times and the absence of a contrast agent, our study suggests the application of T2 mapping in pre-operative glioma grading is feasible. more...
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- 2021
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15. Matrix metallopeptidase 9 and placental growth factor may correlate with collateral status based on whole-brain perfusion combined with multiphase computed tomography angiography
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Weibin Gu, Yuehua Pu, Ya-Rong Ding, Xin Liu, Liping Liu, Qixuan Lu, Xinxuan Yang, Yuan Cai, and Bo Yang
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Adult ,Male ,0301 basic medicine ,Placental growth factor ,medicine.medical_specialty ,Adolescent ,Computed Tomography Angiography ,Collateral Circulation ,Perfusion scanning ,Positive correlation ,Brain Ischemia ,Young Adult ,03 medical and health sciences ,0302 clinical medicine ,Internal medicine ,Occlusion ,Humans ,Medicine ,Aged ,Placenta Growth Factor ,Computed tomography angiography ,Aged, 80 and over ,medicine.diagnostic_test ,business.industry ,Brain ,General Medicine ,Middle Aged ,medicine.disease ,Pathophysiology ,Cerebral Angiography ,Stroke ,Stenosis ,030104 developmental biology ,Matrix Metalloproteinase 9 ,Neurology ,Metalloproteases ,Cardiology ,Female ,Neurology (clinical) ,business ,Perfusion ,030217 neurology & neurosurgery - Abstract
Objective The aim of this study was to find out the relationship between serum biomarkers and cerebral collateral status in acute ischemic stroke with cerebral large artery atherosclerosis. Methods We enrolled patients with ischemic stroke due to large artery atherosclerosis within 7 days of symptom onset, age 18-80 years, from August 2016 to December 2017. Twelve biomarkers representing different pathophysiological mechanisms were tested after admission. Whole-brain perfusion combined with multiphase computed tomography angiography was performed to assess cerebral collateral structure and function. Results Fifty-two patients completed the test of candidate biomarkers and recruited in this study. The mean age was 55.0 (11.1) years, 42 (80.8%) patients were male, 20 (38.5%) had poor collateral, 36 (69.2%) patients had anterior circulation stenosis or occlusion. Compared with poor collateral group, the level of MMP-9 (135,475.00 pg/ml vs. 103,612.00 pg/ml, p = 0.040) and PGF (5.75 pg/ml vs. 3.46 pg/ml, p = 0.046) was significantly higher in good collateral group. The adjusted OR (95%CI) of MMP-9 and PGF were 5.533 (1.10-27.74, p = 0.038), 7.73 (1.41-42.39, p = 0.018), respectively. sTie-2 level had a positive correlation with proportion of Tmax 4-6 (r = 0.302, p = 0.033) and HMW-KGN had negative correlation with proportion of Tmax 6-8 (r = -0.338, p = 0.02). After adjustment, the correlation of sTie-2 level and proportion of Tmax 4-6 was statistically significant (p = 0.003), and correlation of HMW-KGN and Tmax6-8 was not statistically significant (p = 0.056). Discussion Serum PGF and MMP-9 levels may correlate with collateral status based on MP-CTA in acute ischemic stroke patients with cerebral large artery atherosclerosis. Higher PGF and MMP-9 concentration associated with good collateral status. more...
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- 2021
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16. Research on coal wall failure and stability control technology of large coal seams with a soft and thick seam
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Weibin Guo, Gang Wang, Yuhui Li, and Dengfeng Chen
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advanced deep‐hole static water injection technology ,field experiment ,large mining height ,numerical simulation ,rib spalling ,soft coal seam ,Technology ,Science - Abstract
Abstract To address the issues of coal rib instability and high occurrence of roof falls in high extraction height fully mechanized coal mining of soft coal seams, this study comprehensively employs theoretical analysis, numerical calculations, and field industrial experiments. By analyzing the distribution characteristics of coal rib displacement and deformation instability zones under different mechanical parameters of soft coal seams, the instability mechanism of coal ribs in high extraction height mining of thick and soft coal seams is revealed, and corresponding stability control techniques for high extraction height coal ribs and supports are developed. The study shows that the stability of coal ribs in high extraction height mining fields of soft and thick coal seams decreases as the values of mechanical parameters decrease. In other words, the smaller the cohesion and deformation parameters of the coal body, the more prone the coal rib is to roof falls. By utilizing advanced deep‐hole static water infusion technology, the frequency of roof falls in extremely soft high extraction height working faces is reduced by 80%, the average depth of roof falls is decreased by 35%, and the average length of roof falls is reduced by 50%. The stability of the coal ribs is effectively improved. more...
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- 2024
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17. Intraluminal Thrombus and Outcomes of Patients With Acute Large Vessel Occlusive Stroke Undergoing Endovascular Treatment
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Weibin Gu, Wanying Duan, Yufei Wei, Yuan Cai, Hongyi Yan, Ximing Nie, Zhongrong Miao, Zhe Zhang, Xinyi Hou, Jiejie Li, Miao Wen, Liping Liu, Qixuan Lu, Xinyi Leng, Dacheng Liu, Yuesong Pan, Yongjun Wang, Yarong Ding, Ning Ma, Yuehua Pu, and Zhonghua Yang more...
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Male ,medicine.medical_specialty ,Large vessel ,030204 cardiovascular system & hematology ,03 medical and health sciences ,0302 clinical medicine ,Internal medicine ,medicine ,Humans ,Intraluminal thrombus ,Endovascular treatment ,Acute ischemic stroke ,Aged ,Ischemic Stroke ,Advanced and Specialized Nursing ,medicine.diagnostic_test ,business.industry ,Endovascular Procedures ,Angiography, Digital Subtraction ,Thrombosis ,Middle Aged ,Treatment Outcome ,Occlusive stroke ,Ischemic stroke ,Angiography ,Cardiology ,Female ,Neurology (clinical) ,Cardiology and Cardiovascular Medicine ,business ,030217 neurology & neurosurgery - Abstract
Background and Purpose: Intraluminal thrombus (ILT) is an emerging imaging marker in acute ischemic stroke. We aimed to investigate the association of ILT with outcomes of acute large vessel occlusion (LVO) patients receiving endovascular treatment. Methods: Acute LVO stroke patients who underwent endovascular treatment within 24 hours, in a prospective, nationwide registry were enrolled. Pretreatment digital subtraction angiography was reviewed for the presence of ILT. The primary outcome was 90-day functional dependence (modified Rankin Scale scores, 3–6). Secondary outcomes included 24-hour LVO, 90-day death, and symptomatic intracranial hemorrhage. Results: Among 711 patients enrolled, 75 (10.5%) with ILT were less likely to have 90-day functional dependence compared with those without ILT (adjusted odds ratio, 0.53 [95% CI, 0.31–0.90]; P =0.021). The same trend was found among those with successful reperfusion (modified Thrombolysis in Cerebral Infarction 2b–3; P =0.008) but not in those without successful reperfusion ( P =0.107). Presence of ILT was also independently associated with a lower rate of 24-hour LVO (adjusted odds ratio 0.34 [95% CI, 0.13–0.89]; P =0.028). However, those with or without ILT had similar risks of symptomatic intracranial hemorrhage and 90-day death. Conclusions: Among acute LVO patients receiving endovascular treatment, pretreatment ILT-positive patients may have a better 90-day functional outcome (versus ILT-negative) but similar risk of death and symptomatic intracranial hemorrhage. The possibly favorable effect of ILT patients remained in those with successful reperfusion. Registration: URL: http://www.chictr.org.cn ; Unique identifier: ChiCTR1900022154. more...
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- 2021
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18. Cortical Microinfarcts Associated With Worse Outcomes in Patients With Acute Ischemic Stroke Receiving Endovascular Treatment
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Yufei Wei, Yuehua Pu, Yuesong Pan, Ximing Nie, Wanying Duan, Dacheng Liu, Hongyi Yan, Qixuan Lu, Zhe Zhang, Zhonghua Yang, Miao Wen, Weibin Gu, Xinyi Hou, Ning Ma, Xinyi Leng, Zhongrong Miao, Liping Liu, Ning Wang, Shengli Chen, Meng Zhang, Wei Li, Xu Zhang, Kaifu Ke, Xiaoyuan Niu, Bing Sun, Xin Zhang, Huishan Du, Hongyan Li, Jin Wu, Changqing Wang, Yingqiong Xiong, Yong Liu, Jun Yang, Guode Wu, and Xiaonan Song more...
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Adult ,Male ,medicine.medical_specialty ,Arterial Occlusive Diseases ,Brain Ischemia ,Internal medicine ,medicine ,Humans ,In patient ,Prospective Studies ,Registries ,Endovascular treatment ,Acute ischemic stroke ,Aged ,Aged, 80 and over ,Cerebral Cortex ,Advanced and Specialized Nursing ,medicine.diagnostic_test ,business.industry ,Endovascular Procedures ,Magnetic resonance imaging ,Cerebral Infarction ,Odds ratio ,Middle Aged ,Magnetic Resonance Imaging ,Stroke ,Treatment Outcome ,Cardiology ,Female ,Neurology (clinical) ,Cardiology and Cardiovascular Medicine ,business ,Intracranial Hemorrhages ,Magnetic Resonance Angiography - Abstract
Background and Purpose: We aimed to evaluate the impact of cortical microinfarcts (CMIs) on functional outcome after endovascular treatment in patients with acute ischemic stroke. Methods: In a multicenter registration study for RESCUE-RE (a registration study for Critical Care of Acute Ischemic Stroke After Recanalization), eligible patients with large vessel occlusion stroke receiving endovascular treatment, who had undergone 3T magnetic resonance imaging on admission or within 24 hours after endovascular treatment were analyzed. We evaluated the presence and numbers of CMIs with assessment of axial T1, T2-weighted images, and fluid-attenuated inversion recovery images. The primary outcome was functional dependence or death defined as modified Rankin Scale scores of 3 to 6 at 90 days. Secondary outcomes included early neurological improvement, any intracranial hemorrhage, symptomatic intracranial hemorrhage, and mortality. We investigated the independent associations of CMIs with the outcomes using multivariable logistic regression in overall patients and in subgroups. Results: Among 414 patients (enrolled from July 2018 to May 2019) included in the analyses, 96 (23.2%) patients had at least one CMI (maximum 6). Patients with CMI(s) were more likely to be functionally dependent or dead at 90 days, compared with those without (55.2% versus 37.4%; P P =0.04) and multiple CMIs (CMIs ≥2; adjusted odds ratio, 7.41 [95% CI, 2.48−22.17]; P Conclusions: Acute large vessel occlusion stroke patients receiving endovascular treatment with CMI(s) were more likely to have a poor functional outcome at 90 days, independent of patients’ characteristics. Such associations may be dose-dependent. Registration: URL: http://www.chictr.org.cn ; Unique identifier: ChiCTR1900022154. more...
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- 2020
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19. Association between basilar artery stenosis features, vertebral artery stenosis and perforator stroke after stenting
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Rui Huang, Bo Yang, Feng Gao, Dapeng Mo, Ming Yang, Zhikai Hou, Yifan Liu, Rongrong Cui, Kaijiang Kang, Weibin Gu, Jianfeng He, Xin Lou, Zhongrong Miao, and Ning Ma
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General Medicine - Abstract
Background and Purpose We investigated the relationship between basilar artery (BA) atherosclerotic stenosis features and vertebral artery (VA) stenosis and explored whether BA stenosis features are associated with perforator stroke after stenting. Methods Patients with BA stenosis who underwent HRMRI and DSA were recruited. Patients were divided into proximal BA stenosis and middle-or-distal BA stenosis groups, and then subgroup analyses were performed based on whether they had VA stenosis. BA plaque features were evaluated by HRMRI. Artery stenosis was measured by DSA. The incidence of perforator stroke after BA stenting was recorded, and the potential association between BA stenosis features and perforator stroke was analyzed. Results One hundred and seventy-four patients were consecutively enrolled. Patients with proximal BA stenosis had a higher proportion of severe stenosis than those with middle-or-distal BA stenosis ( P = 0.027). In the subgroup analysis, this difference mainly existed in patients complicated with VA stenosis ( P = 0.023). Patients with proximal BA stenosis had a higher proportion of strong plaque enhancement than those with middle-or-distal BA stenosis ( P Conclusion Patients with proximal BA stenosis had a higher proportion of severe stenosis and strong plaque enhancement, particularly in patients complicated with VA stenosis and VBJ stenosis. Perforator stroke after BA stenting may be related to distribution, burden and characteristics of BA lesions. more...
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- 2023
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20. Small vessel disease burden may not portend unfavorable outcome after thrombectomy for acute large vessel occlusion
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Lina Zheng, Xinyi Leng, Ximing Nie, Hongyi Yan, Xuan Tian, Yuesong Pan, Zhonghua Yang, Miao Wen, Yuehua Pu, Weibin Gu, Zhongrong Miao, Thomas W Leung, and Liping Liu
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Male ,Stroke ,Cost of Illness ,Cerebral Small Vessel Diseases ,Humans ,Radiology, Nuclear Medicine and imaging ,Female ,General Medicine ,Middle Aged ,Aged ,Ischemic Stroke ,Thrombectomy ,Brain Ischemia - Abstract
We aimed to investigate the correlation between an overall cerebral small vessel disease (CSVD) burden and outcomes after endovascular treatment (EVT) for patients with acute ischemic stroke (AIS) due to large vessel occlusion (LVO).In a multicenter registry study, we enrolled patients with EVT for anterior-circulation LVO-stroke. In 3.0-T MR imaging, we assessed 4 CSVD imaging markers, lacunes, white matter hyperintensities, cerebral microbleeds, and enlarged perivascular spaces, each assigned a score of 0 or 1 and summed up to an overall CSVD burden score of 0-4. We dichotomized the overall CSVD severity as none to mild (score 0-2) and moderate to severe (3-4). Primary outcome was 90-day functional dependence or death (modified Rankin Scale (mRS) 3-6). Secondary outcomes included increase in NIH Stroke Scale ≥ 4 within 24 h (early neurological deterioration (END)) and within 7 days, symptomatic intracranial hemorrhage, 90-day mRS 2-6, and 90-day mortality.Among 311 patients (63.0% male; mean age 65.1 ± 12.7 years), 260 (83.6%) had none-to-mild and 51 (16.4%) had moderate-to-severe overall CSVD burden. Moderate-to-severe CSVD burden was not significantly associated with the primary outcome (47.1% versus 45.4%; p0.05 in univariate and multivariate logistic regression), or the secondary outcomes except for a higher risk of END (11.8% versus 3.1%; p0.05 in multivariate analyses). Sensitivity analyses with 0-1 versus 2-4 of the CSVD burden score, and the score as an ordinal variable, showed similar results.An overall moderate-to-severe CSVD burden was not associated with 90-day functional dependence or death, after EVT for anterior-circulation LVO.ChiCTR1900022154 KEY POINTS: • Moderate-to-severe cerebral small vessel disease burden on MRI should not be an exclusion indicator in determining the eligibility of an acute ischemic stroke patient for endovascular treatment. more...
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- 2021
21. Multi-teacher distillation BERT model in NLU tasks
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Jialai SHI and Weibin GUO
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deep pre-training model ,BERT ,multi-teacher distillation ,nature language understanding ,Electronic computers. Computer science ,QA75.5-76.95 - Abstract
Knowledge distillation is a model compression scheme commonly used to solve the problems of large scale and slow inference of BERT constant depth pre-training model.The method of &quot;multi-teacher distillation&quot; can further improve the performance of the student model, while the traditional &quot;one-to-one&quot; mapping method mandatory assignment strategy for the middle layer of the teacher model will lead to the abandonment of most of the middle features.The &quot;one-tomany&quot; mapping method is proposed to solve the problem that the middle layer cannot be aligned during knowledge distillation, and help students master the grammar, reference and other knowledge in the middle layer of the teacher model.Experiments on several data sets in GLUE show that the student model retains 93.9% of the average inference accuracy of the teacher model, while only accounting for 41.5% of the average parameter size of the teacher model. more...
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- 2024
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22. Endovascular treatment with or without intravenous alteplase for acute ischaemic stroke due to basilar artery occlusion
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Ximing Nie, David Wang, Yuehua Pu, Yufei Wei, Qixuan Lu, Hongyi Yan, Xin Liu, Lina Zheng, Jingyi Liu, Xinxuan Yang, Yarong Ding, Dacheng Liu, Wanying Duan, Zhe Zhang, Zhonghua Yang, Miao Wen, Weibin Gu, Xinyi Hou, Xinyi Leng, Yuesong Pan, Zhongrong Miao, and Liping Liu more...
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Cohort Studies ,Stroke ,Treatment Outcome ,Basilar Artery ,Tissue Plasminogen Activator ,Humans ,Multicenter Studies as Topic ,Arterial Occlusive Diseases ,Neurology (clinical) ,Cardiology and Cardiovascular Medicine ,Brain Ischemia ,Ischemic Stroke ,Thrombectomy - Abstract
Background and purposeIt remains controversial if endovascular treatment (EVT) can improve the outcome of patients with acute basilar artery occlusion (BAO). This study aims to compare the functional outcomes between EVT with and without intravenous thrombolysis (IVT) first in patients who had acute ischaemic stroke (AIS) due to BAO.MethodsPatients who had AIS with BAO who underwent EVT within 24 hours of onset were enrolled in this multicentre cohort study, and the efficacy and safety were compared between IVT+EVT and direct EVT. The primary outcome was 90-day functional independence. All outcomes were assessed with adjusted OR (aOR) from the multivariable logistic regression. In addition, a meta-analysis was performed on all recently published pivotal studies on functional independence after EVT in patients with BAO.ResultsOf 310 enrolled patients with BAO, 241 (78%) were treated with direct EVT and 69 (22%) with IVT+EVT. Direct EVT was associated with a worse functional outcome (aOR, 0.46 (95% CI 0.24 to 0.85), p=0.01). IVT+EVT was associated with a lower percentage of patients who needed ≥3 passes of stent retriever (10.14% vs 20.75%). The meta-analysis regression revealed a potential positive correlation between bridging with IVT first and functional independence (r=0.14 (95% CI 0.05 to 0.24), pConclusionsThis study showed that compared with direct EVT, EVT with IVT first was associated with better functional outcomes in patients with BAO treated within 24 hours of onset. The meta-analysis demonstrated similar favourable efficacy of IVT first followed by EVT in patients with BAO. more...
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- 2021
23. Recent advances and future perspectives of Ruddlesden–Popper perovskite oxides electrolytes for all‐solid‐state batteries
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Chongyang Zhou, Weibin Guo, Jiayao Fan, Naien Shi, Yi Zhao, Xu Yang, Zhen Ding, Min Han, and Wei Huang
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all‐solid‐state batteries ,ionic conductivity improvement strategies ,Ruddlesden–Popper perovskite oxides ,solid‐state electrolytes ,Materials of engineering and construction. Mechanics of materials ,TA401-492 ,Information technology ,T58.5-58.64 - Abstract
Abstract All‐solid‐state batteries equipped with solid‐state electrolytes (SSEs) have gained significant interest due to their enhanced safety, energy density, and longevity in comparison to traditional liquid organic electrolyte‐based batteries. However, many SSEs, such as sulfides and hydrides, are highly sensitive to water, limiting their practical use. As one class of important perovskites, the Ruddlesden–Popper perovskite oxides (RPPOs), show great promise as SSEs due to their exceptional stability, particularly in terms of water resistance. In this review, the crystal structure and synthesis methods of RPPOs SSEs are first introduced in brief. Subsequently, the mechanisms of ion transportation, including oxygen anions and lithium‐ions, and the relevant strategies for enhancing their ionic conductivity are described in detail. Additionally, the progress made in developing flexible RPPOs SSEs, which are critical for flexible and wearable electronic devices, has also been summarized. Furthermore, the key challenges and prospects for exploring and developing RPPOs SSEs in all‐solid‐state batteries are suggested. This review presents in detail the synthesis methods, the ion transportation mechanism, and strategies to enhance the room temperature ionic conductivity of RPPOs SSEs, providing valuable insights on enhancing their ionic conductivity and thus for their practical application in solid‐state batteries. more...
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- 2024
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24. Adverse Outcomes Associated With Higher Mean Blood Pressure and Greater Blood Pressure Variability Immediately After Successful Embolectomy in Those With Acute Ischemic Stroke, and the Influence of Pretreatment Collateral Circulation Status
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Yongjun Wang, Yarong Ding, Ning Ma, Xinyi Leng, Ximing Nie, Miao Wen, Zhe Zhang, Zhongrong Miao, Dacheng Liu, Stephen M. Davis, Yufei Wei, Hongyi Yan, Xinyi Hou, Liping Liu, Weibin Gu, Qixuan Lu, Yuan Cai, Yuehua Pu, Bernard Yan, Gaoting Ma, Zhonghua Yang, Penglian Wang, and Yuesong Pan more...
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Male ,endovascular treatment ,medicine.medical_specialty ,medicine.medical_treatment ,collateral ,Embolectomy ,Collateral Circulation ,Ischemia ,Internal medicine ,medicine ,Humans ,Prospective Studies ,Registries ,Prospective cohort study ,Stroke ,Aged ,Ischemic Stroke ,Original Research ,medicine.diagnostic_test ,business.industry ,Endovascular Procedures ,blood pressure ,medicine.disease ,Collateral circulation ,Cerebral Angiography ,Clinical research ,Blood pressure ,Mean blood pressure ,Treatment Outcome ,Acute Disease ,Hypertension ,Preoperative Period ,Cardiology ,outcome ,Female ,blood pressure variability ,Cardiology and Cardiovascular Medicine ,business ,Cerebral angiography ,Follow-Up Studies - Abstract
Background To investigate whether collateral status could modify the associations between post‐thrombectomy blood pressure (BP) measures and outcomes. Methods and Results Patients with anterior‐circulation large‐vessel‐occlusion successfully recanalized in a multicenter endovascular thrombectomy registry were enrolled. Pretreatment collateral status was graded and dichotomized (good/poor) in angiography. Maximum, minimum, and mean systolic BP (SBP) and BP variability (assessed by the SD, coefficient of variation) during the initial 24 hours after endovascular thrombectomy were obtained. The primary outcome was unfavorable 90‐day outcome (modified Rankin Scale score 3–6). Secondary outcomes included symptomatic intracranial hemorrhage and 90‐day mortality. Adjusted odds ratios (aOR) of BP parameters over the outcomes were obtained in all patients and in patients with good/poor collaterals. Among 596 patients (mean age 66 years; 59.9% males), 302 (50.7%) patients had unfavorable 90‐day outcome. In multivariable analyses, higher mean SBP (aOR, 1.59 per 10 mm Hg increment; 95% CI, 1.26–2.02; P 140 mm Hg (versus ≤120 mm Hg; aOR, 4.27; 95% CI, 1.66–10.97; P =0.002), and higher SBP SD (aOR, 1.08 per 1‐SD increment; 95% CI, 1.01–1.16; P =0.02) were respectively associated with unfavorable 90‐day outcome in patients with poor collateral but not in those with good collateral. A marginal interaction between SBP coefficient of variation tertiles and collaterals on 90‐day functional outcome ( P for interaction, 0.09) was observed. A significant interaction between SBP coefficient of variation tertiles and collaterals on 90‐day mortality ( P for interaction, 0.03) was observed. Conclusions Higher postprocedural BP is associated with 90‐day unfavorable outcomes after successful endovascular thrombectomy in patients with poor collateral. Registration URL: https://www.chictr.org.cn ; Unique identifier: ChiCTR1900022154. more...
- Published
- 2021
25. Response Characteristics of Anchored Surrounding Rock in Roadways Under the Influence of Vibrational Waves
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Hongsheng Wang, Siyuan Wei, Guang’an Zhu, Yuxin Yuan, and Weibin Guo
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pressure bumping ,vibration wave propagation ,anchored surrounding rock ,rock bolting support ,FLAC3D numerical simulation ,Technology ,Engineering (General). Civil engineering (General) ,TA1-2040 ,Biology (General) ,QH301-705.5 ,Physics ,QC1-999 ,Chemistry ,QD1-999 - Abstract
The vibration waves generated by pressure fluctuations can substantially impair and jeopardize the structural integrity of roadway anchorage within adjacent rock formations, thereby presenting a significant risk to the safety and operational efficiency of mining activities. In order to address this issue and elucidate the response characteristics of roadway-anchored surrounding rock subjected to P-wave and S-wave influences, this study employs a roadway that is experiencing actual impact instability within a mine situated in Xinjiang as the engineering context. The synchrosqueezing wavelet transform, enhanced by a Butterworth filter, is utilized to isolate and filter seismic wave data, thereby facilitating the extraction of time-frequency signals corresponding to both P-waves and S-waves. Subsequently, a dynamic numerical model is developed to simulate the propagation of these vibration waves. An analysis of the dynamic behavior and response characteristics of P-waves and S-waves is performed, focusing on their interaction with roadway anchoring within the surrounding rock at various stages of propagation. The results indicate that weak rock and plastic zones can absorb vibrational waves, with S-waves exhibiting a stronger absorption effect than P-waves. S-waves contribute to increased stress and displacement in the surrounding rock, leading to the accumulation of elastic energy and an expansion of the plastic zone. The rapid fluctuations in the axial force of bolts along the roadway, caused by S-waves, can result in instability within the roadway. The research findings possess considerable reference value and practical applicability for the design of anti-scour support systems in roadways. more...
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- 2024
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26. Autonomous wind turbine inspection using a quadrotor
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Alessandro Rizzo, Liang Cheng, Weibin Gu, Dewen Hu, Yabing Cao, and Kimon P. Valavanis
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0301 basic medicine ,Wind power ,Explosive material ,Blades, Inspection, Wind turbines, Cameras, Maintenance engineering, Poles and towers, Navigation ,business.industry ,Computer science ,Inspection ,Cameras ,Turbine ,Maintenance engineering ,Navigation ,Task (project management) ,03 medical and health sciences ,030104 developmental biology ,0302 clinical medicine ,Blades ,Poles and towers ,Work (electrical) ,Sea breeze ,Wind turbines ,Submarine pipeline ,business ,030217 neurology & neurosurgery ,Marine engineering - Abstract
There has been explosive growth of wind farm installations in recent years due to the fact that wind energy is gaining worldwide popularity. However, the maintenance of these offshore or onshore wind turbines, especially in remote areas, remains a challenging task. In this work, vision-based autonomous wind turbine inspection using a quadrotor is designed based on realistic assumptions. Both simulation and Hardware-In-the-Loop (HIL) testing results have shown the effectiveness of the proposed approach. more...
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- 2020
27. Outcome of endovascular recanalization for intracranial in-stent restenosis
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Zhongrong Miao, Yifan Liu, Kaijiang Kang, Guofeng Ma, Feng Gao, Dapeng Mo, Weibin Gu, Bo Yang, Xingquan Zhao, Ning Ma, Ming Yang, and Xing Chen
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Male ,medicine.medical_specialty ,medicine.medical_treatment ,030204 cardiovascular system & hematology ,Culprit ,03 medical and health sciences ,0302 clinical medicine ,Restenosis ,Angioplasty ,medicine ,Humans ,cardiovascular diseases ,Myocardial infarction ,Stroke ,Aged ,Retrospective Studies ,Arterial stenosis ,business.industry ,Endovascular Procedures ,Graft Occlusion, Vascular ,Stent ,General Medicine ,Middle Aged ,medicine.disease ,Surgery ,Stenosis ,Treatment Outcome ,Female ,Stents ,Neurology (clinical) ,business ,030217 neurology & neurosurgery ,Angioplasty, Balloon - Abstract
Background and purposeIn-stent restenosis (ISR) is one of the long-term adverse outcomes of endovascular angioplasty and stenting for symptomatic intracranial arterial stenosis. In this study, we try to evaluate the safety and efficacy of endovascular treatment for intracranial ISR.MethodsWe retrospectively collected patients with intracranial ISR who underwent endovascular treatment from June 2012 to August 2019 at a high-volume stroke center. Successful recanalization was defined as ≤30% residual stenosis. Stroke, myocardial infarction, and death after stenting within 30 days were used to evaluate periprocedural safety. Recurrent stroke in the territory of the culprit vessel and re-ISR in patients with clinical and vascular imaging follow-up data were used to evaluate the long-term outcome.Results32 patients (59.6±7.2 years old) with ISR were recruited, including 22 patients (68.8%) treated with balloon dilatation, 8 patients (25%) with stenting, and 2 patients (6.3%) with failed procedures. Successful recanalization was achieved in 71.9% (23/32) of patients. There was no stroke, myocardial infarction or death within 30 days after the procedure. Recurrent stroke was found in 10.7% (3/28) of the patients, and re-ISR was found in 42.1% (8/19) of the patients. The re-ISR rate was lower in patients with stenting than in those with balloon dilatation (0% vs 57.1%, p=0.090), and in patients with successful recanalization than in those with unsuccessful recanalization (33.3% vs 75.0%, p=0.352), but with no statistically significant difference.ConclusionsThe periprocedural safety of endovascular treatment for intracranial ISR may be acceptable, but the long-term rates of recurrent stroke and re-ISR remain at high levels. more...
- Published
- 2019
28. An Integrated Control Architecture for a Cloud-based Unmanned Aerial Vehicle System with Lossy Networks
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Carlos Perez-Montenegro, Elisa Capello, Alessandro Rizzo, and Weibin Gu
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0209 industrial biotechnology ,Computer science ,business.industry ,Network packet ,Wireless network ,020208 electrical & electronic engineering ,Real-time computing ,Cloud computing ,02 engineering and technology ,Kalman filter ,Networked control system ,Telecommunications network ,Model predictive control ,020901 industrial engineering & automation ,0202 electrical engineering, electronic engineering, information engineering ,business ,Control logic - Abstract
Unmanned Aerial Vehicles (UAVs) have been successfully employed in cooperative tasks over recent years, particularly in the applications for smart cities. In such scenario, a networked control system (NCS) framework is usually adopted since measurement and actuation data are mainly transmitted through communication networks. This paper proposes an integrated control architecture for a Cloud-based fixed-wing UAV system, where the control logic resides in the Cloud and sensing and actuating signals are transmitted over a realistic wireless network. The proposed control strategy leverages model predictive control (MPC) and a specialized Kalman filter in combination with two ad-hoc buffers, which enables simultaneous compensation for measurement and control input packet dropouts. Simulations of a nonlinear aircraft model show the effectiveness and advantages of proposed integrated scheme over an existing linear quadratic (LQ)-based control strategy. more...
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- 2019
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29. A Survey of Artificial Neural Networks with Model-based Control Techniques for Flight Control of Unmanned Aerial Vehicles
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Kimon P. Valavanis, Alessandro Rizzo, Weibin Gu, and Matthew J. Rutherford
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0209 industrial biotechnology ,Artificial neural network ,Computational complexity theory ,Computer science ,Process (engineering) ,media_common.quotation_subject ,System identification ,Fidelity ,Control engineering ,02 engineering and technology ,System dynamics ,020901 industrial engineering & automation ,Control theory ,0202 electrical engineering, electronic engineering, information engineering ,020201 artificial intelligence & image processing ,Time complexity ,media_common - Abstract
Model-based control (MBC) techniques have been successfully developed for flight control applications of unmanned aerial vehicles (UAVs) in recent years. However, their heavy reliance on the fidelity of the plant model coupled with high computational complexity make the design and implementation process challenging. To overcome such challenges, attention has been focused on the use of artificial neural networks (ANNs) to study complex systems since they show promise in system identification and controller design, to say the least. This survey aims to provide a literature review on combining MBC techniques with ANNs for UAV flight control, with the goal of laying the foundation for efficient controller designs with performance guarantees. A brief discussion on frequently-used ANNs is presented along with an analysis of their time complexity. Classification/comparison of existing dynamic modeling approaches and control techniques is provided. Challenging research questions and an envisaged control architecture are also posed for future development. more...
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- 2019
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30. Preliminary application of CT perfusion source images for evaluating regional collateral circulation in unilateral Moyamoya disease
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Jing Xue, Yujing Peng, Peiyi Gao, Ning Wang, Yuesong Pan, Weibin Gu, Yu Qi, Weiqi Chen, Yanan Zhang, and Lina Hao
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medicine.medical_specialty ,medicine.diagnostic_test ,business.industry ,Perfusion scanning ,Gold standard (test) ,Digital subtraction angiography ,medicine.disease ,Collateral circulation ,body regions ,Cohen's kappa ,Angiography ,Medicine ,Radiology, Nuclear Medicine and imaging ,heterocyclic compounds ,Original Article ,Radiology ,Moyamoya disease ,business ,Stroke - Abstract
Background Collateral flow is associated with clinical outcomes for patients with Moyamoya disease and served as a parameter for patient selection of therapeutic strategies. Therefore, we explored whether a noninvasive imaging modality, computed tomography perfusion (CTP) source images (CTP-Sis), could be used to identify the presence and intensity of collateral flow using digital subtraction angiography (DSA) as a gold standard for collateral flow. Methods CTP-Sis and DSA were performed for 24 patients with unilateral Moyamoya disease. A collateral grading system was developed based on arterial and venous phase CTP-Sis, imitating the DSA score system. Two neuroradiologists scored the DSA images using a collateral grading scale for the regions of interest corresponding to the Alberta Stroke Program Early computed tomography Score (ASPECTS) methodology. Another two neuroradiologists scored CTP-Sis in a similar manner. Agreement between the CTP-Sis and DSA consensus scores was determined, including kappa statistics. Results The agreement between the CTP-Sis and DSA consensus readings was moderate to strong, with a weighted kappa value of 0.768 [95% confidence interval (CI), 0.703-0.832], but there was a better agreement for readers of CTP-Sis, as compared with those of DSA. The sensitivity and specificity for identifying collaterals with CTP-Sis were 0.714 (95% CI, 0.578-0.851) and 0.995 (95% CI, 0.985-1.000), respectively. Conclusions CTP-Sis could help identify in a noninvasive manner the presence and intensity of collateral flow in patients with unilateral Moyamoya disease using DSA as a gold standard. Further study with a large number of cases is warranted. Further application of this method to other cerebrovascular diseases including acute ischemic stroke can also be warranted. more...
- Published
- 2019
31. The influence of wing morphology upon intraspecific divergence in birds: A global study of subspecies richness
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Haiying Fan, Weibin Guo, Buge Lin, Zhiqing Hu, Changcao Wang, and Shaobin Li
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Dispersal ,Gene flow ,Hand-wing index ,Subspecies richness ,Zoology ,QL1-991 - Abstract
Since the time of Darwin, subspecies have been recognized as an initial stage in the evolution of species. However, the impact of dispersal on subspecies richness in birds globally has received little attention, despite dispersal being a key factor in determining the rate of evolution and playing a significant role in evolutionary divergence. Therefore, it is important to conduct a comprehensive study to address this issue. In this study, we aimed to assess the association between subspecies richness (measured by the number of subspecies) and dispersal ability (measured by the hand-wing index) on a global scale, using a dataset of over 7000 bird species. Our results revealed a negative correlation between dispersal ability and the number of subspecies, without any quadratic correlation. The wing is a crucial phenotypic trait for birds, and the concept of subspecies is important in speciation theory and conservation biology. Therefore, our findings not only enhance our understanding of the association between avian morphological traits and evolutionary divergence but also have implications for the conservation of avian species diversity. more...
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- 2024
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32. Friction and wear performance of laser peen textured surface under starved lubrication
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Yongxiang Hu, Kangmei Li, Weibin Gu, and Zhenqiang Yao
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Surface (mathematics) ,Materials science ,Microscope ,Mechanical Engineering ,Metallurgy ,Abrasive ,Surfaces and Interfaces ,Laser ,Surfaces, Coatings and Films ,law.invention ,Mechanics of Materials ,law ,Lubrication ,Adhesive wear ,Texture (crystalline) ,Laser processing - Abstract
Laser peen texturing (LPT), which is a new surface texturing technology, was proposed to fabricate micro-dimple arrays on copper surface. Pin-on-disk experiments were conducted under different normal loads and sliding speeds to investigate friction and wear behaviors of untextured and textured samples in starved lubrication. It was found that friction performance of the surface is improved significantly after LPT. Microscope observation and EDS analysis showed that textured surface could reduce both abrasive and adhesive wear as compared to untextured surface. Results also indicated that an optimum texture density might exist at which surface shows the best friction and wear behavior. more...
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- 2014
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33. Outcome of endovascular recanalization for intracranial in-stent restenosis.
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Kaijiang Kang, Feng Gao, Dapeng Mo, Ming Yang, Yifan Liu, Bo Yang, Xing Chen, Weibin Gu, Guofeng Ma, Xingquan Zhao, Zhong-Rong Miao, and Ning Ma
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ENDOVASCULAR surgery ,CATHETERIZATION ,CEREBRAL arteriosclerosis ,DEATH ,MYOCARDIAL infarction ,PATIENT safety ,SURGICAL stents ,STROKE ,SURGICAL complications ,TREATMENT effectiveness ,RETROSPECTIVE studies ,DESCRIPTIVE statistics - Abstract
Background and purpose In-stent restenosis (ISR) is one of the long-term adverse outcomes of endovascular angioplasty and stenting for symptomatic intracranial arterial stenosis. In this study, we try to evaluate the safety and efficacy of endovascular treatment for intracranial ISR. Methods We retrospectively collected patients with intracranial ISR who underwent endovascular treatment from June 2012 to August 2019 at a high-volume stroke center. Successful recanalization was defined as ≤30% residual stenosis. Stroke, myocardial infarction, and death after stenting within 30 days were used to evaluate periprocedural safety. Recurrent stroke in the territory of the culprit vessel and re-ISR in patients with clinical and vascular imaging follow-up data were used to evaluate the long-term outcome. Results 32 patients (59.6±7.2 years old) with ISR were recruited, including 22 patients (68.8%) treated with balloon dilatation, 8 patients (25%) with stenting, and 2 patients (6.3%) with failed procedures. Successful recanalization was achieved in 71.9% (23/32) of patients. There was no stroke, myocardial infarction or death within 30 days after the procedure. Recurrent stroke was found in 10.7% (3/28) of the patients, and re-ISR was found in 42.1% (8/19) of the patients. The re-ISR rate was lower in patients with stenting than in those with balloon dilatation (0% vs 57.1%, p=0.090), and in patients with successful recanalization than in those with unsuccessful recanalization (33.3% vs 75.0%, p=0.352), but with no statistically significant difference. Conclusions The periprocedural safety of endovascular treatment for intracranial ISR may be acceptable, but the long-term rates of recurrent stroke and re-ISR remain at high levels. [ABSTRACT FROM AUTHOR] more...
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- 2020
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34. Relationship between surface roughness and subsurface crack depth during grinding of optical glass BK7
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Kangmei Li, Zhenqiang Yao, and Weibin Gu
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Optical glass ,Materials science ,Abrasive ,Metals and Alloys ,Industrial and Manufacturing Engineering ,Computer Science Applications ,Grinding ,law.invention ,Cracking ,Optical microscope ,law ,Modeling and Simulation ,Surface grinding ,Ceramics and Composites ,Surface roughness ,Geotechnical engineering ,Extrusion ,Composite material - Abstract
Subsurface damages induced by grinding strongly influence the mechanical strength and optical quality of optical glasses. It is meaningful to rapid evaluate the depth of subsurface cracking through the measurement of surface roughness under different grinding parameters. Based on the features of surface and subsurface cracks as well as the kinetic analysis of surface grinding, the relationship between surface roughness and subsurface crack depth was established. Surface grinding experiments for optical glass BK7 were conducted. Utilizing optical microscope, optical profiling system and polishing-etching technique, the dependence of surface roughness and subsurface crack depth on grinding parameters was systematically analyzed. The predicted model of the relationship between surface roughness and subsurface crack depth was compared with experimental results. It was found that the relationship between surface roughness and subsurface crack depth is influenced by the half apex angle of abrasive grain as well as the magnitude of extra grain extrusion. more...
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- 2012
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35. Investigation of grinding modes in horizontal surface grinding of optical glass BK7
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Haolin Li, Weibin Gu, and Zhenqiang Yao
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Engineering drawing ,Materials science ,Metals and Alloys ,Diamond grinding ,Industrial and Manufacturing Engineering ,Computer Science Applications ,Grinding ,Mechanism (engineering) ,Brittleness ,Etching (microfabrication) ,Modeling and Simulation ,Indentation ,Surface grinding ,Ceramics and Composites ,Surface roughness ,Composite material - Abstract
Grinding is one of the most important processes to manufacture hard-brittle materials such as optical glass. It is often desired to increase the material removal rate while maintaining the desired surface quality. The success of this approach relies on the better understanding of the relationship between the grinding modes and the characteristics of surface and subsurface integrities. Based on the kinematic analysis of horizontal surface grinding as well as the features of grinding-induced cracks, four grinding modes were proposed. They are brittle mode, semi-brittle mode, semi-ductile mode and ductile mode. The horizontal surface grinding of optical glass BK7 has been studied using diamond grinding wheel. The four different grinding modes have been investigated with the characteristics of surface morphologies before and after etching, surface roughness, subsurface damages as well as indentation depth. It was found that the level of surface roughness and depth of subsurface damage were strongly dependent on grinding mode. This study provides valuable insights into the material removal mechanism and the dependence of surface and subsurface integrities on grinding mode. more...
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- 2011
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36. RIDED-2D: A RULE-BASED INSTANTANEOUS DENOISING AND EDGE DETECTION METHOD FOR 2D RANGE SCAN LINE
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Yao-jie Zhu, Jian Wang, Zhenqiang Yao, Dong-Qing Shen, Xin-Guang Liang, Fang-Fang Lu, Weibin Gu, Lin Mei, Jin Wu, Quan-Zhang An, Yunchang Xin, and Xueping Zhang
- Subjects
Pixel ,Computational complexity theory ,business.industry ,Noise reduction ,Clock rate ,Rule-based system ,Image processing ,Scan line ,Edge detection ,Artificial Intelligence ,Computer vision ,Computer Vision and Pattern Recognition ,Artificial intelligence ,business ,Algorithm ,Software ,Mathematics - Abstract
Edge detection is often regarded as a basic step in range image processing by virtue of its crucial effect. The majority of existing edge detection methods cannot satisfy the requirement of efficiency in many industrial applications due to huge computational costs. In this paper, a novel instantaneous method, named RIDED-2D is proposed for denoising and edge detection for 2D scan line in range images. In the method, silhouettes of 2D scan line are classified into eight types by defining a few new coefficients. Several discriminant criteria on large noise filtering and edge detection are stipulated based on qualitative feature analysis on each type. Selecting some feature point candidates, a practical parameter learning method is provided to determine the threshold set, along with the implementation of an integrated algorithm by merging calculation steps. Because all the coefficients are established based on distances among the points or their ratio, RIDED-2D is inherently invariant to translation and rotation transformations. Furthermore, a forbidden region approach is proposed to eliminate interference of the mixed pixels. Key performances of RIDED-2D are evaluated in detail by including computational complexity, time expenditure, accuracy and stability. The results indicate that RIDED-2D can detect edge points accurately from several real range images, in which large noises and systematic noises are involved, and the total processing time is less than 0.1 millisecond on an ordinary PC platform using the integrated algorithm. Comparing with other state-of-the-art edge detection methods qualitatively, RIDED-2D exhibits a prominent advantage on computational efficiency. Thus, the proposed method qualifies for real-time processing in stringent industrial applications. Besides, another contribution of this paper is to introduce CPU clock counting technique to evaluate the performance of the proposed algorithm, and suggest a convenient and objective way to estimate the algorithm's time expenditure in other platforms. more...
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- 2011
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37. Evaluation of subsurface crack depth during scratch test for optical glass BK7
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Weibin Gu, Zhenqiang Yao, and Kangmei Li
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Optical glass ,Brittleness ,Materials science ,Scratch ,Mechanical Engineering ,Abrasive ,Scratch hardness ,Fracture (geology) ,Deformation (meteorology) ,Composite material ,computer ,computer.programming_language ,Scratch test - Abstract
To get insight into the deformation and fracture behavior of brittle materials during abrasive process, scratch tests with linearly increasing normal load and constant normal load were conducted on BK7 using Vickers indenters. The effect of the applied normal load on the characteristics of surface cracks as well as the square of the scratch depth was found insensitive to the two load conditions discussed here. By taking both scratch and residual depths into consideration, a model of scratch hardness for brittle material was developed. Based on this scratch hardness, the correlation between the depth of the subsurface cracks and the scratch depth was established and was found in general agreement with the experimental results. more...
- Published
- 2011
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38. Evaluation of surface cracking in micron and sub-micron scale scratch tests for optical glass BK7
- Author
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Weibin Gu and Zhenqiang Yao
- Subjects
Materials science ,Mechanical Engineering ,Grinding ,Cracking ,Brittleness ,Mechanics of Materials ,Scratch ,Indentation ,Vickers hardness test ,Forensic engineering ,Fracture (geology) ,Composite material ,Deformation (engineering) ,computer ,computer.programming_language - Abstract
In order to obtain the fundamental information on the deformation and fracture behavior of brittle materials during precision and ultra-precision grinding, micron and sub-micron scale scratch tests were conducted on optical glass BK7 using Vickers indenters. Three types of surface cracking were observed around the scratch grooves. They are lateral cracking, radial cracking and cracking in front of the moving indenter. It is found that lateral cracking is the main damage type due to its large damage size and low crack initiation load. The effect of surface cracking on the relationship between the normal load and the square of scratch depth was studied. The plastic zone size as well as the sliding blister field strength was expressed as a function of the contact zone size of the indenter. A prediction model for the size of damage zone induced by lateral cracking was established and was compared with experimental results. more...
- Published
- 2011
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39. Material removal of optical glass BK7 during single and double scratch tests
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Xin-Guang Liang, Zhenqiang Yao, and Weibin Gu
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Materials science ,business.industry ,Surfaces and Interfaces ,Nanoindentation ,Condensed Matter Physics ,Surfaces, Coatings and Films ,law.invention ,Grinding ,Brittleness ,Optics ,Optical microscope ,Machining ,Mechanics of Materials ,Scratch ,law ,Materials Chemistry ,Nanoindenter ,business ,computer ,Groove (music) ,computer.programming_language - Abstract
In order to get insight into the characteristics of chipping behaviors and material removal mechanism during grinding, both single and double scratch tests for optical glass BK7 were performed on a nanoindenter. Utilizing optical microscope, optical profiling system and displacement transducers, the scratch morphology, material removal volume and scratch depth were analyzed with applied normal load and scratch separation distance. In ductile mode of single scratching, obvious plastic ridges were formed on both sides of the groove and the volume of material removed is negligible. Under loading conditions discussed here, no obvious chipping occurs around the single scratch even when lateral and radial cracks were generated. During double scratching, three types of cracking interaction were observed and resulted in different chipping features. In brittle scratch mode, the material removal volume during double scratching is strongly dependent on separation distance. There exists a critical separation distance where the material removal volume reached its maximum. The difference in depths of the two sequential scratches was also found to be sensitive to both normal load and separation distance. more...
- Published
- 2011
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40. Effects of Crofton weed Ageratina adenophora on assemblages of Carabidae (Coleoptera) in the Yunnan Province, South China
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Weiguo Sang, Hongbin Liang, Jan C. Axmacher, and Weibin Gu
- Subjects
Ecology ,Biodiversity ,Introduced species ,Vegetation ,Biology ,Generalist and specialist species ,biology.organism_classification ,Invasive species ,Ageratina adenophora ,Species evenness ,Animal Science and Zoology ,Weed ,Agronomy and Crop Science - Abstract
Crofton weed (Ageratina adenophora) is a highly invasive weed that has spread into several provinces of southern China. This study compares carabid assemblages originating from native pastures with assemblages in Crofton weed dominated communities in the Lancang County, Yunnan Province, to assess how the invasion of this neophyte impacts the community structure of ground-dwelling arthropods. Over a period of 16 months, a total of 1574 carabid beetles representing 28 species were collected at two types of pasture, and 679 carabid beetles representing 34 species at stands of Crofton weed. The most common carabid species, Tetragonoderus arcuatus and Harpalus indicus, were mostly found in the pastures, while four of the five rarest species were present exclusively under Crofton weed. Alpha-diversity and evenness of carabid assemblages were greater under Crofton weed. Three distinct groups of carabid species were separated according to indicator values and a characterization of habitats: habitat generalists, Crofton weed specialists and native pasture specialists. The distribution of carabid species was related to environmental parameters such as depth of litter layer, total phosphorus, height of vegetation, amount of fresh biomass and pH of the soil. According to this study, the invasion of Crofton weed will alter the structure of carabid communities, but will not necessarily reduce the alpha-diversity of carabid assemblages. more...
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- 2008
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41. Diversity of carabids (Coleoptera, Carabidae) in the desalinized agricultural landscape of Quzhou county, China
- Author
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Yunhui Liu, Jan C. Axmacher, Weibin Gu, and Zhenrong Yu
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Soil salinity ,Ecology ,Biodiversity ,Species diversity ,engineering.material ,Biology ,Chine ,Salinity ,Habitat ,Abundance (ecology) ,engineering ,Animal Science and Zoology ,Fertilizer ,Agronomy and Crop Science - Abstract
Diversity and species composition of carabid beetles were investigated at Quzhou county in the North China Plain. The study area was originally affected by high salinity and desalinized in three stages in 1973, 1978 and 1982. At sites desalinized in 1982, carabids were sampled at field margins as well as inside fields to investigate the role of field margins as refuge habitats. Furthermore, samples were taken from field margins desalinized in 1973 and 1978, respectively, to explore long-term developments of carabid assemblages following desalinization. At margins, soil salinity, N contents and the number of plant species as well as the height of dominant plants were recorded and their correlation with the species composition of carabids explored. Overall carabid diversity at Quzhou was low compared to areas not affected by high salinity. Field margins yielded significantly higher numbers of both species and individuals, whereas assemblages within the field had a low diversity and a homogeneous species composition. Carabid diversity slightly increased in relation to decreased soil salt contents and time elapsed since desalinization. These results may be explained by field margins serving as refuge to many carabid species and by an overall low species pool of carabids in Quzhou due to former high salinity, current high levels of fertilizer and pesticide applications, and by a comparatively low colonization rate of carabids to the area. As different carabid species varied strongly in their reaction to environmental parameters, the preservation of a diverse set of habitats will best protect the current diversity of these beetles in the agricultural landscape of Quzhou. more...
- Published
- 2006
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42. Li-Rich Mn-Based Cathode Materials for Li-Ion Batteries: Progress and Perspective
- Author
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Weibin Guo, Zhangzhao Weng, Chongyang Zhou, Min Han, Naien Shi, Qingshui Xie, and Dong-Liang Peng
- Subjects
Li-rich Mn-based cathode materials ,anionic redox activity ,modification strategy ,lithium-ion batteries ,Inorganic chemistry ,QD146-197 - Abstract
The development of cathode materials with high specific capacity is the key to obtaining high-performance lithium-ion batteries, which are crucial for the efficient utilization of clean energy and the realization of carbon neutralization goals. Li-rich Mn-based cathode materials (LRM) exhibit high specific capacity because of both cationic and anionic redox activity and are expected to be developed and applied as cathode materials for a new generation of high-energy density lithium-ion batteries. Nevertheless, the difficulty of regulating anionic redox reactions poses significant challenges to LRM, such as low initial Coulombic efficiency, poor rate capability, and fast cycling capacity and voltage decay. To address the existing challenges of LRM, this review introduces their basic physicochemical characteristics in detail, analyzes the original causes of these challenges, focuses on the recent progress of the modification strategies, and then especially discusses the development prospects of LRM from different aspects. more...
- Published
- 2023
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43. Effect of oral administration of gabapentin on the minimum alveolar concentration of isoflurane in cats
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Hangbin Chen, Huan Yang, Mengqing Li, Haojie Peng, Weibin Guo, and Meng Li
- Subjects
anesthesia ,gabapentin ,minimum alveolar concentration (MAC) ,isoflurane ,cat ,Veterinary medicine ,SF600-1100 - Abstract
ObjectiveTo determine if oral gabapentin decreases the minimum alveolar concentration (MAC) of isoflurane in cats.Study designProspective, randomized, blinded, crossover, and experimental study.AnimalsA total of six healthy adult cats (three male, three female) aged 18–42 months, weighing 3.31 ± 0.26 kg.MethodsCats were randomly given oral gabapentin (100 mg cat−1) or placebo 2 h before starting MAC determination, with the crossover treatment given at least 7 days apart. Anesthesia was induced and maintained with isoflurane in oxygen. Isoflurane MAC was determined in duplicate using an iterative bracketing technique and tail clamp method. Hemodynamic and other vital variables were recorded at each stable isoflurane concentration and were compared between gabapentin and placebo treatments at lowest end-tidal isoflurane concentration when cats did not respond to tail clamping. A paired t-test was used to compare normally distributed data, and a Wilcoxon signed-rank test was applied for non-normally distributed data. Significance was set at p < 0.05. Data are mean ± standard deviation.ResultsIsoflurane MAC in the gabapentin treatment was 1.02 ± 0.11%, which was significantly lower than that in the placebo treatment (1.49 ± 0.12%; p < 0.001), decreasing by 31.58 ± 6.94%. No significant differences were found in cardiovascular and other vital variables between treatments.Conclusion and clinical relevanceOral administration of gabapentin 2 h before starting MAC determination had a significant isoflurane MAC-sparing effect in cats with no observed hemodynamic benefit. more...
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- 2023
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44. How do helpers slow senescence in a Tibetan cooperatively breeding bird?
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Haiying Fan, Weibin Guo, and Xin Lu
- Subjects
helper effect ,life history ,lifetime fitness ,longevity ,reproductive aging ,sociality ,Ecology ,QH540-549.5 - Abstract
Abstract Sociality is known to be capable of slowing individual senescence, but it is unclear whether the effect differs for reproduction versus survival in a sex‐specific manner. Here we predict that social benefits are directed toward (1) somatic maintenance in harsh environments where high survival prospects of adults over young intensify the trade‐off between current and future reproduction, and (2) females that invest more in reproduction and have a greater marginal effect if their survival is improved by reducing the cost of reproduction. These two predictions are tested with cooperatively breeding Tibetan ground tits (Pseudopodoces humilis). Across the lifetime, both mothers and fathers with helpers did not differ in brood size at fledging from their counterparts without helpers. The presence of helpers reduced survival senescence of both parents, but mothers benefited more than fathers from receiving help. Consequently, the inherent sex difference in life span and along with lifetime reproductive success, as expressed in breeders of never‐receiving help, became no longer obvious. The model of social modulation for senescence should facilitate the persistence of cooperative breeding in challenging environments. more...
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- 2022
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45. The Instability Characteristics and Displacement Law of Coal Wall Containing Joint Fissures in the Fully Mechanized Working Face with Great Mining Height
- Author
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Weibin Guo, Yuhui Li, and Gang Wang
- Subjects
coal wall stability ,rib-spalling ,joint fissures ,physical simulation ,numerical simulation ,Technology - Abstract
Coal wall rib-spalling is regarded as a key technical problem influencing safe and efficient mining of fully mechanized working face with great mining height (FGH) while the coal wall stability is influenced by the strength of the coal body, of which the internal joint fissures have a crucial impact on the strength of the coal body. This research attempted to explore how the coal wall stability of FGH is influenced by the occurrence of joint fissures. This paper uses physical and numerical simulations to systematically analyze the instability characteristics and displacement law of FGH. Research results show that the form and scope of the instability of coal wall rib-spalling depend on the state of the coal seam joint fissures development area, and the development state of coal seam joint fissures is related to the combination of the coal seam joints; under the condition of hard coal, the coal wall stability is better at the inclination angle of 90°, and less stable at 45° and 135°; under the condition of medium-hard coal and joint surface inclination angle of 45° and 135°, the smaller the spacing of joint surface, the larger the area of the working face rib-spalling, and the less stable the coal wall. more...
- Published
- 2022
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46. Case Study on the Mechanism of Influence of Stoppage on Ground Pressure under Different Rates of Advance
- Author
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Xiaoxu Gao, Xinyu Shi, and Weibin Guo
- Subjects
Engineering (General). Civil engineering (General) ,TA1-2040 - Abstract
Because of daily maintenance, equipment damage, gas overrun, and other force majeure factors, the continuous stopping of the working face causes the roof pressure to accumulate, which leads to causing accidents such as coal wall spalling and roof falling. To address the roof safety problem caused by continuous stoppages, the 620 working face in the Huangling mining area is taken as the research object. Through field measurement, theoretical analysis, numerical simulation, and other research methods, the influence and mechanism of stopping pressure under different rates of advance are studied. The results show that the velocity factor of roof load transfer is positively correlated with the advancing velocity of the working face; the reasonable length of the suspended roof is mainly affected by the number of caving holes and the effect of pressure relief; and comparing the two stages of advance speed of 4.8 m/d and 12.8 m/d, the periodic weighting step distance of the latter increases by 24.4% compared with the former, and the rate of increase of support load caused by stopping mining increases by 42.1% compared with the former. The roof pressure accumulation caused by stopping mining is increased. Taking appropriate measures for local forced caving of the working face can release the roof pressure and reduce the risk of local caving of the working face. The study can provide a theoretical basis for roof control of continuous stopping under similar engineering conditions. more...
- Published
- 2021
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47. The Effect of Joint Damage on a Coal Wall and the Influence of Joints on the Abutment Pressure on a Fully Mechanised Working Face with Large Mining Height
- Author
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Weibin Guo, Shengwei Zhang, and Yuhui Li
- Subjects
Physics ,QC1-999 - Abstract
Coal wall spalling is regarded as a key technical problem influencing safe and efficient mining of large-mining-height working faces while the distribution of abutment pressure within the limit equilibrium zone (LEZ) influences coal wall spalling within a large-mining-height working face. This research attempted to explore the distribution characteristics of abutment pressure within the LEZ in a large-mining-height working face. For this purpose, the influences of the orientation of joints on mechanical characteristics of coal with joints and on the distribution of abutment pressure within the LEZ in the large-mining-height working face were analysed by theoretical analysis and numerical simulation. Research results show that the damage variable of coal with joints first rises, then decreases, and finally increases with increasing dip angle of the joints; as the azimuth of the joints increases, the damage variable first declines, then increases; the damage variable gradually declines with increasing joint spacing; an increase in the dip angle of joints corresponds to first reduction, then growth, and a final decrease of the abutment pressure at the same position in front of the coal walls; on certain conditions, the abutment pressure at the same position within the LEZ first rises, then declines as the azimuth of joints increases; with the growth of the joint spacing, the abutment pressure at the same position within the LEZ rises. The dip angle and azimuth of joints marginally affect the abutment pressure within the LEZ. more...
- Published
- 2021
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48. A genome-wide investigation of microsatellite mismatches and the association with body mass among bird species
- Author
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Haiying Fan and Weibin Guo
- Subjects
Microsatellites ,Heterozygosity ,Evolution ,Mutation rate ,Birds ,Medicine ,Biology (General) ,QH301-705.5 - Abstract
Mutation rate is usually found to covary with many life history traits of animals such as body mass, which has been readily explained by the higher number of mutation opportunities per unit time. Although the precise reason for the pattern is not yet clear, to determine the universality of this pattern, we tested whether life history traits impact another form of genetic mutation, the motif mismatches in microsatellites. Employing published genome sequences from 65 avian species, we explored the motif mismatches patterns of microsatellites in birds on a genomic level and assessed the relationship between motif mismatches and body mass in a phylogenetic context. We found that small-bodied species have a higher average mismatches and we suggested that higher heterozygosity in imperfect microsatellites lead to the increase of motif mismatches. Our results obtained from this study imply that a negative body mass trend in mutation rate may be a general pattern of avian molecular evolution. more...
- Published
- 2018
- Full Text
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