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According to the World Health Organization (1999), more than 90% of the estimated 36 million people with HIV/AIDS are living in developing countries with agricultural pursuits as both their primary means of income and food source, suggesting a critical relationship between the three areas of human health, animal health and agricultural economic development in emerging world areas. While there are organizations that provide treatment, intervention or aid in terms of one or more of these areas, a review of the literature did not reveal any which deal with the three in the aggregate. This paper examines the correlations that exist between human health, animal health, and economic development and sets forth a trivariate approach known as the Systems Integration Model (SIM), as the proposed interventional concept. The SIM intervention concept targets all three areas as opposed to being singularly focused on one, which has widespread implications for organizational responses to diseases of poverty, such as HIV/AIDS.