1. What causes hidradenitis suppurativa ?—15 years after
- Author
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Wayne Wpf Gulliver, Antonio Martorell, Hessel H. van der Zee, Aude Nassif, Qiang Ju, Yildiz Hayran, Elena Nikiphorou, Łukasz Matusiak, Farida Benhadou, John R. Ingram, Philippe Guillem, Angel As Byrd, Marcos Ma González-López, Gabriella Fabbrocini, Christos C. Zouboulis, Ralf Paus, Benjamin Perin, Iltefat H. Hamzavi, Nisha Ns Chandran, Joslyn S. Kirby, Evangelos J. Giamarellos-Bourboulis, Angelo V. Marzano, John Jw Frew, Alexa Ab Kimball, Andre Nogueira da Costa, Gregor B.E. Jemec, Martin M. Okun, Hideki Fujita, Maria Mp Konstantinou, Jacek C Szepietowski, Thrasyvoulos Tzellos, Lauren Lav Orenstein, Michelle Ma Lowes, Till Ta Röhn, Andrea Szegedi, Baoxi Wang, José C. Pascual, Robert Re Hunger, Errol P. Prens, Georgios Nikolakis, Amanda S. MacLeod, Barbara Horváth, Sophie Hue, Universidad de Cantabria, Dermatology, Zouboulis, C. C., Benhadou, F., Byrd, A. S., Chandran, N. S., Giamarellos-Bourboulis, E. J., Fabbrocini, G., Frew, J. W., Fujita, H., Gonzalez-Lopez, M. A., Guillem, P., Gulliver, W. P. F., Hamzavi, I., Hayran, Y., Horvath, B., Hue, S., Hunger, R. E., Ingram, J. R., Jemec, G. B. E., Ju, Q., Kimball, A. B., Kirby, J. S., Konstantinou, M. P., Lowes, M. A., Macleod, A. S., Martorell, A., Marzano, A. V., Matusiak, L., Nassif, A., Nikiphorou, E., Nikolakis, G., Nogueira da Costa, A., Okun, M. M., Orenstein, L. A. V., Pascual, J. C., Paus, R., Perin, B., Prens, E. P., Rohn, T. A., Szegedi, A., Szepietowski, J. C., Tzellos, T., Wang, B., and van der Zee, H. H.
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0301 basic medicine ,T-Lymphocytes ,Autoimmunity ,Biochemistry ,030207 dermatology & venereal diseases ,0302 clinical medicine ,Risk Factors ,Hidradenitis suppurativa ,610 Medicine & health ,B-Lymphocytes ,INSULIN-RESISTANCE ,hair follicle ,pathogenesis ,Smoking ,Bacterial Infections ,Sciences bio-médicales et agricoles ,Experimental research ,Phenotype ,NCSTN MUTATIONS ,PYODERMA-GANGRENOSUM ,Cholinergic system ,Cytokines ,ALOPECIA-AREATA ,ELEVATED LEVELS ,CHOLINERGIC SYSTEM ,medicine.medical_specialty ,Genotype ,Pain ,Complement C5a ,Dermatology ,03 medical and health sciences ,ACNE INVERSA ,medicine ,BRONCHIAL EPITHELIAL-CELLS ,Humans ,Molecular Biology ,business.industry ,Pruritus ,Inflammatory skin disease ,AUTOINFLAMMATORY SYNDROME ,hidradenitis suppurativa ,The Renaissance ,medicine.disease ,inflammatory skin disease ,inflammatory skin diseases ,030104 developmental biology ,Mutation ,acne inversa ,Transcriptome ,business ,SKIN - Abstract
The 14 authors of the first review article on hidradenitis suppurativa (HS) pathogenesis published 2008 in EXPERIMENTAL DERMATOLOGY cumulating from the 1st International Hidradenitis Suppurativa Research Symposium held March 30-April 2, 2006 in Dessau, Germany with 33 participants were prophetic when they wrote "Hopefully, this heralds a welcome new tradition: to get to the molecular heart of HS pathogenesis, which can only be achieved by a renaissance of solid basic HS research, as the key to developing more effective HS therapy." (Kurzen et al. What causes hidradenitis suppurativa? Exp Dermatol 2008;17:455). Fifteen years later, there is no doubt that the desired renaissance of solid basic HS research is progressing with rapid steps and that HS has developed deep roots among inflammatory diseases in Dermatology and beyond, recognized as "the only inflammatory skin disease than can be healed". This anniversary article of 43 research-performing authors from all around the globe in the official journal of the European Hidradenitis Suppurativa Foundation e.V. (EHSF e.V.) and the Hidradenitis Suppurativa Foundation, Inc (HSF USA) summarizes the evidence of the intense HS clinical and experimental research during the last 15 years in all aspects of the disease and provides information of the developments to come in the near future., info:eu-repo/semantics/published
- Published
- 2020
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