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1. Midregional Proatrial Natriuretic Peptide (MRproANP) is associated with vertebral fractures and low bone density in patients with chronic obstructive pulmonary disease (COPD)

Author

Trudzinski, Franziska C., Jörres, Rudolf A., Alter, Peter, Watz, Henrik, Vogelmeier, Claus F., Kauczor, Hans-Ulrich, Thangamani, Subasini, Debic, Manuel, Welte, Tobias, Behr, Jürgen, Kahnert, Kathrin, Bals, Robert, Herr, Christian, Heußel, Claus Peter, Biederer, Jürgen, von Stackelberg, Oyunbileg, Fähndrich, Sebastian, Wouters, Emiel F. M., Waschki, Benjamin, Rabe, Klaus F., Herth, Felix J. F., and Palm, Viktoria

Published
2024
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3. Selective androgen receptor modulation for muscle weakness in chronic obstructive pulmonary disease: a randomised control trial

Author

Mohan, Divya, Rossiter, Harry, Watz, Henrik, Fogarty, Charles, Evans, Rachael A, Man, William, Tabberer, Maggie, Beerahee, Misba, Kumar, Subramanya, Millns, Helen, Thomas, Sebin, Tal-Singer, Ruth, Russell, Alan J, Holland, Marie Claire, Akinseye, Chika, Neil, David, and Polkey, Michael I

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Chronic Obstructive Pulmonary Disease, Lung, Clinical Trials and Supportive Activities, Clinical Research, Rehabilitation, Prevention, Physical Rehabilitation, 6.1 Pharmaceuticals, 6.7 Physical, Evaluation of treatments and therapeutic interventions, Respiratory, Male, Humans, Female, Receptors, Androgen, Pulmonary Disease, Chronic Obstructive, Muscle Weakness, Exercise, Double-Blind Method, COPD pathology, COPD pharmacology, exercise, pulmonary rehabilitation, Respiratory System, Cardiovascular medicine and haematology, Clinical sciences
Abstract

BackgroundSelective androgen receptor modulators (SARMs) increase muscle mass via the androgen receptor. This phase 2A trial investigated the effects of a SARM, GSK2881078, in conjunction with exercise, on leg strength in patients with chronic obstructive pulmonary disease (COPD) and impaired physical function.Methods47 postmenopausal women and 50 men with COPD (forced expiratory volume in 1 s 30%-65% predicted; short physical performance battery score: 3-11) were enrolled into a randomised double-blind, placebo control trial. Patients were randomised 1:1 to once daily placebo or oral GSK2881078 (females: 1.0 mg; males: 2.0 mg) for 13 weeks with a concurrent home-exercise programme, involving strength training and physical activity. Primary endpoints were change from baseline in leg strength at 90 days (one-repetition maximum; absolute (kg) and relative (% change)) and multiple safety outcomes. Secondary endpoints included lean body mass, physical function and patient-reported outcomes.ResultsGSK2881078 increased leg strength in men. The difference in adjusted mean change from baseline and adjusted mean percentage change from baseline between treatment and placebo were: for women, 8.0 kg (90% CI -2.5 to 18.4) and 5.2% (90% CI -4.7 to 15.0), respectively; for men, 11.8 kg (90% CI -0.5 to 24.0) and 7.0% (90% CI 0.5 to 13.6), respectively. Lean body mass increased, but no changes in patient-reported outcomes were observed. Reversible reductions in high-density lipoprotein-cholesterol and transient elevations in hepatic transaminases were the main treatment-related safety findings.ConclusionsGSK2881078 was well tolerated and short-term treatment increased leg strength, when expressed as per cent predicted, in men with COPD more than physical training alone.Trial registration numberNCT03359473.

Published
2023

4. Objectively Measured Physical Activity in Patients with COPD: Recommendations from an International Task Force on Physical Activity.

Author

Demeyer, Heleen, Mohan, Divya, Burtin, Chris, Vaes, Anouk W, Heasley, Matthew, Bowler, Russell P, Casaburi, Richard, Cooper, Christopher B, Corriol-Rohou, Solange, Frei, Anja, Hamilton, Alan, Hopkinson, Nicholas S, Karlsson, Niklas, Man, William D-C, Moy, Marilyn L, Pitta, Fabio, Polkey, Michael I, Puhan, Milo, Rennard, Stephen I, Rochester, Carolyn L, Rossiter, Harry B, Sciurba, Frank, Singh, Sally, Tal-Singer, Ruth, Vogiatzis, Ioannis, Watz, Henrik, Lummel, Rob Van, Wyatt, Jeremy, Merrill, Debora D, Spruit, Martijn A, Garcia-Aymerich, Judith, and Troosters, Thierry

Subjects
Chronic Obstructive Pulmonary Disease, Lung, Prevention, Clinical Research, Cardiovascular, Oral and gastrointestinal, Respiratory, physical activity, accelerometery, standardization, methodology, Chronic Lung Disease Biomarker and Clinical Outcome Assessment Qualification Consortium Task Force on Physical Activity, Physical activity
Abstract

Physical activity (PA) is of key importance for health among healthy persons and individuals with chronic obstructive pulmonary disease (COPD). PA has multiple dimensions that can be assessed and quantified objectively using activity monitors. Moreover, as shown in the published literature, variable methodologies have been used to date to quantify PA among individuals with COPD, precluding clear comparisons of outcomes across studies. The present paper aims to provide a summary of the available literature for the rationale behind using objectively measured PA and proposes a standardized methodology for assessment, including standard operating procedures for future research. The present paper, therefore, describes the concept of PA, reports on the importance of PA, summarizes the dimensions of PA, provides a standard operating procedure on how to monitor PA using objective assessments, and describes the psychometric properties of objectively measured PA. The present international task force recommends implementation of the standard operating procedure for PA data collection and reporting in the future. This should further clarify the relationship between PA and clinical outcomes, test the impact of treatment interventions on PA in individuals with COPD, and successfully propose a PA endpoint for regulatory qualification in the future.

Published
2021

6. Decline of COPD exacerbations in clinical trials over two decades -- a systematic review and meta-regression

Author

Andreas, Stefan, Röver, Christian, Heinz, Judith, Straube, Sebastian, Watz, Henrik, and Friede, Tim

Subjects
Statistics - Applications
Abstract

BACKGROUND: An important goal of chronic obstructive pulmonary disease (COPD) treatment is to reduce the frequency of exacerbations. Some observations suggest a decline in exacerbation rates in clinical trials over time. A more systematic understanding would help to improve the design and interpretation of COPD trials. METHODS: We performed a systematic review and meta-regression of the placebo groups in published randomized controlled trials reporting exacerbations as an outcome. A Bayesian negative binomial model was developed to accommodate results that are reported in different formats; results are reported with credible intervals (CI) and posterior tail probabilities ($p_B$). RESULTS: Of 1114 studies identified by our search, 55 were ultimately included. Exacerbation rates decreased by 6.7% (95% CI (4.4, 9.0); $p_B$ < 0.001) per year, or 50% (95% CI (36, 61)) per decade. Adjusting for available study and baseline characteristics such as forced expiratory volume in 1 s (FEV1) did not alter the observed trend considerably. Two subsets of studies, one using a true placebo group and the other allowing inhaled corticosteroids in the "placebo" group, also yielded consistent results. CONCLUSIONS: In conclusion, this meta-regression indicates that the rate of COPD exacerbations decreased over the past two decades to a clinically relevant extent independent of important prognostic factors. This suggests that care is needed in the design of new trials or when comparing results from older trials with more recent ones. Also a considerable effect of adjunct therapy on COPD exacerbations can be assumed., Comment: 11 pages, 4 figures

Published
2019
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7. Lymphangioleiomyomatose

Author

Wirtz, Hubert, Kirsten, Detlef, Watz, Henrik, Kreuter, Michael, editor, Costabel, Ulrich, editor, Herth, Felix JF, editor, and Kirsten, Detlef, editor

Published
2022
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11. Non-typeable Haemophilus influenzae–Moraxella catarrhalis vaccine for the prevention of exacerbations in chronic obstructive pulmonary disease: a multicentre, randomised, placebo-controlled, observer-blinded, proof-of-concept, phase 2b trial

Author

Brusselle, Guy, Corhay, Jean-Louis, Janssens, Eduard, Janssens, Wim, Leys, Mathias, Ferguson, Murdo, Fitzgerald, Mark, Maltais, François, Mayers, Irvin, McNeil, Shelly, Pek, Bonavuth, Bourdin, Arnaud, Boyer, Laurent, Couturaud, Francis, Dussart, Luc, Andreas, Stefan, Illies, Gabriele, Eich, Andreas, Ludwig-Sengpiel, Andrea, Watz, Henrik, Blasi, Francesco, Centanni, Stefano, Papi, Alberto, Pomari, Carlo, Echave-Sustaeta, José Maria, Llorca Martínez, Eleuterio, Narejos Pérez, Silvia, Pascual-Guardia, Sergi, Pérez Vera, Mercè, Puente-Maestu, Luis, Terns Riera, Manuel, Anderson, William, Choudhury, Gourab, De-Soyza, Anthony, Saralaya, Dinesh, Wilkinson, Tom MA, Boscia III, Joseph, Chinsky, Kenneth, Dunn, Leonard, Erb, David, Fogarty, Charles, Downey, Herman Jackson, Kerwin, Edward, Kunz, Craig, Poling, Terry, Sellman, Richard, Sigal, Barry, Southard, John, Spangenthal, Selwyn, Tannous, Ziad, Testa, Marco, Casula, Daniela, Di Maro, Gennaro, Lattanzi, Maria, Moraschini, Luca, Schoonbroodt, Sonia, Tasciotti, Annaelisa, Arora, Ashwani K, and Wilkinson, Tom M A

Published
2022
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12. The arginine methyltransferase PRMT7 promotes extravasation of monocytes resulting in tissue injury in COPD

Author

Günes Günsel, Gizem, Conlon, Thomas M., Jeridi, Aicha, Kim, Rinho, Ertüz, Zeynep, Lang, Niklas J., Ansari, Meshal, Novikova, Mariia, Jiang, Dongsheng, Strunz, Maximilian, Gaianova, Mariia, Hollauer, Christine, Gabriel, Christina, Angelidis, Ilias, Doll, Sebastian, Pestoni, Jeanine C., Edelmann, Stephanie L., Kohlhepp, Marlene Sophia, Guillot, Adrien, Bassler, Kevin, Van Eeckhoutte, Hannelore P., Kayalar, Özgecan, Konyalilar, Nur, Kanashova, Tamara, Rodius, Sophie, Ballester-López, Carolina, Genes Robles, Carlos M., Smirnova, Natalia, Rehberg, Markus, Agarwal, Charu, Krikki, Ioanna, Piavaux, Benoit, Verleden, Stijn E., Vanaudenaerde, Bart, Königshoff, Melanie, Dittmar, Gunnar, Bracke, Ken R., Schultze, Joachim L., Watz, Henrik, Eickelberg, Oliver, Stoeger, Tobias, Burgstaller, Gerald, Tacke, Frank, Heissmeyer, Vigo, Rinkevich, Yuval, Bayram, Hasan, Schiller, Herbert B., Conrad, Marcus, Schneider, Robert, and Yildirim, Ali Önder

Published
2022
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17. Long-term safety and efficacy of dupilumab in patients with moderate-to-severe asthma (TRAVERSE): an open-label extension study

Author

Wechsler, Michael E, Ford, Linda B, Maspero, Jorge F, Pavord, Ian D, Papi, Alberto, Bourdin, Arnaud, Watz, Henrik, Castro, Mario, Nenasheva, Natalia M, Tohda, Yuji, Langton, David, Cardona, Guido, Domingo, Christian, Park, Hae Sim, Chapman, Kenneth R, Mao, Xuezhou, Zhang, Yi, Khan, Asif H, Deniz, Yamo, Rowe, Paul J, Kapoor, Upender, Khokhar, Faisal A, Mannent, Leda P, Ruddy, Marcella, Laws, Elizabeth, Amin, Nikhil, and Hardin, Megan

Published
2022
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24. Measurement of urinary Dickkopf-3 uncovered silent progressive kidney injury in patients with chronic obstructive pulmonary disease

Author

Schunk, Stefan J., Beisswenger, Christoph, Ritzmann, Felix, Herr, Christian, Wagner, Martina, Triem, Sarah, Hütter, Gregor, Schmit, David, Zewinger, Stephen, Sarakpi, Tamim, Honecker, Anja, Mahadevan, Peer, Boor, Peter, Wagenpfeil, Stefan, Jörres, Rudolf, Watz, Henrik, Welte, Tobias, Vogelmeier, Claus F., Gröne, Hermann-Josef, Fliser, Danilo, Speer, Thimoteus, and Bals, Robert

Published
2021
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25. Expiratory Venous Volume and Arterial Tortuosity are Associated with Disease Severity and Mortality Risk in Patients with COPD: Results from COSYCONET.

Author

Stoleriu, Mircea Gabriel, Pienn, Michael, Joerres, Rudolf A, Alter, Peter, Fero, Tamas, Urschler, Martin, Kovacs, Gabor, Olschewski, Horst, Kauczor, Hans-Ulrich, Wielpütz, Mark, Jobst, Bertram, Welte, Tobias, Behr, Jürgen, Trudzinski, Franziska C, Bals, Robert, Watz, Henrik, Vogelmeier, Claus F, Biederer, Jürgen, and Kahnert, Kathrin

Published
2024
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26. Relationship between clinical and radiological signs of bronchiectasis in COPD patients: Results from COSYCONET

Author

Stefan, Andreas, Robert, Bals, Jürgen, Behr, Kathrin, Kahnert, Burkhard, Bewig, Bahmer, Thomas, Roland, Buhl, Ralf, Ewert, Beate, Stubbe, Joachim H, Ficker, Manfred, Gogol, Christian, Grohé, Rainer, Hauck, Matthias, Held, Berthold, Jany, Markus, Henke, Felix, Herth, Gerd, Höffken, Hugo A, Katus, Anne-Marie, Kirsten, Henrik, Watz, Rembert, Koczulla, Klaus, Kenn, Juliane, Kronsbein, Cornelia, Kropf-Sanchen, Christoph, Lange, Peter, Zabel, Michael, Pfeifer, Winfried J, Randerath, Werner, Seeger, Michael, Studnicka, Christian, Taube, Helmut, Teschler, Hartmut, Timmermann, Christian, Virchow J., Claus, Vogelmeier, Ulrich, Wagner, Tobias, Welte, Hubert, Wirtz, Lehnert, Doris, Struck, Birte, Krabbe, Lenka, Arikan, Barbara, Tobias, Julia, Spangel, Gina, Teng, Julia, Essen, Ruhrlandklinik gGmbH., Pieper, Jeanette, Gleiniger, Margret, Markworth, Britta, Hinz, Zaklina, Hundack-Winter, Petra, Burmann, Ellen, Wons, Katrin, Rieber, Ulrike, Schaufler, Beate, Seibert, Martina, Schwedler, Katrin, Michalewski, Sabine, Rohweder, Sonja, Kiel, Campus, Berger, Patricia, Schottel, Diana, Klöser, Manuel, Janke, Vivien, Untsch, Rosalie, Graf, Jana, Reichel, Anita, Weiß, Gertraud, Traugott, Erich, Ziss, Barbara, Kietzmann, Ilona, Schrade-Illmann, Michaela, Polte, Beate, Böckmann, Cornelia, Hübner, Gudrun, Sterk, Lena, Wirz, Anne, Kahnert, Kathrin, Jörres, Rudolf A., Kauczor, Hans-Ulrich, Biederer, Jürgen, Jobst, Bertram, Alter, Peter, Biertz, Frank, Mertsch, Pontus, Lucke, Tanja, Lutter, Johanna I., Trudzinski, Franziska C., Behr, Jürgen, Bals, Robert, Watz, Henrik, Vogelmeier, Claus F., and Welte, Tobias

Published
2020
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27. Real-world walking cadence in people with COPD

Author

Delgado-Ortiz, Laura, primary, Ranciati, Saverio, additional, Arbillaga-Etxarri, Ane, additional, Balcells, Eva, additional, Buekers, Joren, additional, Demeyer, Heleen, additional, Frei, Anja, additional, Gimeno-Santos, Elena, additional, Hopkinson, Nicholas S., additional, de Jong, Corina, additional, Karlsson, Niklas, additional, Louvaris, Zafeiris, additional, Palmerini, Luca, additional, Polkey, Michael I., additional, Puhan, Milo A., additional, Rabinovich, Roberto A., additional, Rodríguez Chiaradia, Diego A., additional, Rodriguez-Roisin, Robert, additional, Toran-Montserrat, Pere, additional, Vogiatzis, Ioannis, additional, Watz, Henrik, additional, Troosters, Thierry, additional, and Garcia-Aymerich, Judith, additional

Published
2024
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29. Characteristics of Current Smokers versus Former Smokers with COPD and Their Associations with Smoking Cessation Within 4.5 Years: Results from COSYCONET

Author

Alter, Peter, primary, Stoleriu, Cosmina, additional, Kahnert, Kathrin, additional, Henke, Markus, additional, Bals, Robert, additional, Trudzinski, Franziska, additional, Watz, Henrik, additional, Speicher, Tim, additional, Söhler, Sandra, additional, Welte, Tobias, additional, Rabe, Klaus, additional, Wouters, Emiel, additional, Vogelmeier, Claus, additional, and Jörres, Rudolf, additional

Published
2023
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30. Investigating the prognostic value of digital mobility outcomes in patients with chronic obstructive pulmonary disease: a systematic literature review and meta-analysis

Author

Buttery, Sara C., primary, Williams, Parris J., additional, Alghamdi, Saeed M., additional, Philip, Keir E.J., additional, Perkins, Alexis, additional, Kallis, Constantinos, additional, Quint, Jennifer K., additional, Polkey, Michael I., additional, Breuls, Sofie, additional, Buekers, Joren, additional, Chynkiamis, Nikolaos, additional, Delgado-Ortiz, Laura, additional, Demeyer, Heleen, additional, Frei, Anja, additional, Garcia-Aymerich, Judith, additional, Gimeno-Santos, Elena, additional, Koch, Sarah, additional, Megaritis, Dimitrios, additional, Polhemus, Ashley, additional, Troosters, Thierry, additional, Vogiatzis, Ioannis, additional, Watz, Henrik, additional, and Hopkinson, Nicholas S., additional

Published
2023
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33. CAT score single item analysis in patients with COPD: Results from COSYCONET

Author

Stefan, Andreas, Robert, Bals, Jürgen, Behr, Kathrin, Kahnert, Burkhard, Bewig, Roland, Buhl, Ralf, Ewert, Beate, Stubbe, Ficker, Joachim H., Manfred, Gogol, Christian, Grohé, Rainer, Hauck, Matthias, Held, Berthold, Jany, Markus, Henke, Felix, Herth, Gerd, Höffken, Katus Hugo, A., Anne-Marie, Kirsten, Henrik, Watz, Rembert, Koczulla, Klaus, Kenn, Juliane, Kronsbein, Cornelia, Kropf-Sanchen, Christoph, Lange, Peter, Zabel, Michael, Pfeifer, Randerath Winfried, J., Werner, Seeger, Michael, Studnicka, Christian, Taube, Helmut, Teschler, Hartmut, Timmermann, Christian, Virchow J., Claus, Vogelmeier, Ulrich, Wagner, Tobias, Welte, Hubert, Wirtz, Lehnert, Doris, Struck, Birte, Krabbe, Lenka, Arikan, Barbara, Tobias, Julia, Speth, Kornelia, Pieper, Jeanette, Gleiniger, Margret, Markworth, Britta, Hinz, Zaklina, Burmann, Ellen, Wons, Katrin, Rieber, Ulrike, Schaufler, Beate, Schwedler, Katrin, Michalewski, Sabine, Rohweder, Sonja, Berger, Patricia, Schottel, Diana, Janke, Vivien, Untsch, Rosalie, Graf, Jana, Reichel, Anita, Weiß, Gertraud, Traugott, Erich, Kietzmann, Ilona, Schrade-Illmann, Michaela, Polte, Beate, Hübner, Gudrun, Marietta von Siemens, Sarah, Alter, Peter, Lutter, Johanna I., Kauczor, Hans-Ulrich, Jobst, Bertram, Bals, Robert, Trudzinski, Franziska C., Söhler, Sandra, Behr, Jürgen, Watz, Henrik, Waschki, Benjamin, Bewig, Burkhard, Jones, Paul W., Welte, Tobias, Vogelmeier, Claus F., Jörres, Rudolf A., and Kahnert, Kathrin

Published
2019
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37. Midregional pro atrial naturetic peptide (MRproANP) and copeptin (COPAVP) as predictors of all- cause mortality in early COPD – Results from COSYCONET

Author

Fähndrich, Sebastian, primary, Herr, Christian, additional, Teuteberg, Sebastian, additional, Alter, Peter, additional, Söhler, Sandra, additional, Soriano, Daniel, additional, Classen, Johanna, additional, Adams, Julia, additional, Weinhold, Victoria, additional, Watz, Henrik, additional, Waschki, Benjamin, additional, Zeller, Tanja, additional, Eichenlaub, Martin, additional, Trudzinski, Franziska C, additional, Michels, Julia D, additional, Omlor, Albert, additional, Seiler, Frederik, additional, Moneke, Isabelle, additional, Biertz, Frank, additional, Stolz, Daiana, additional, Welte, Tobias, additional, Kauczor, Hans-Ulrich, additional, Kahnert, Kathrin, additional, Jörres, Rudolf A, additional, vogelmeier, claus, additional, bals, robert, additional, and group, COSYCONET study, additional

Published
2023
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39. Clinical factors linked to the type of respiratory medication in COPD: Results from COSYCONET

Author

Alter, Peter, primary, Kahnert, Kathrin, additional, Trudzinski, Franziska C., additional, Bals, Robert, additional, Watz, Henrik, additional, Speicher, Tim, additional, Söhler, Sandra, additional, Welte, Tobias, additional, Rabe, Klaus F. R., additional, Wouters, Emiel F. M., additional, Vogelmeier, Claus F., additional, and Jörres, Rudolf A., additional

Published
2023
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40. Proteasome function as a biomarker for severe COPD endotypes

Author

Flexeder, Claudia, primary, Kammerl, Ilona, additional, Karrasch, Stefan, additional, Pedersen, Frauke, additional, Vogelmeier, Claus, additional, Behr, Jürgen, additional, Söhler, Sandra, additional, Watz, Henrik, additional, Peters, Annette, additional, Schulz, Holger, additional, and Meiners, Silke, additional

Published
2023
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41. Study design of a Phase 2 rollover trial of the novel cathepsin C inhibitor BI 1291583 in patients with bronchiectasis

Author

Shteinberg, Michal, primary, Sauter, Wiebke, additional, Chotirmall, Sanjay H, additional, Mcshane, Pamela J, additional, Mall, Marcus, additional, O'Donnell, Anne E, additional, Eickholz, Peter, additional, Watz, Henrik, additional, Hasegawa, Naoki, additional, Eleftheraki, Anastasia, additional, Gupta, Abhya, additional, and Chalmers, James D, additional

Published
2023
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45. Laboratory and free-living gait performance in adults with COPD and healthy controls

Author

Buekers, Joren, primary, Megaritis, Dimitrios, additional, Koch, Sarah, additional, Alcock, Lisa, additional, Becker, Clemens, additional, Bertuletti, Stefano, additional, Bonci, Tecla, additional, Brown, Philip, additional, Buckley, Ellen, additional, Buttery, Sara C., additional, Caulfield, Brian, additional, Cereatti, Andrea, additional, Chynkiamis, Nikolaos, additional, Demeyer, Heleen, additional, Echevarria, Carlos, additional, Frei, Anja, additional, Hansen, Clint, additional, Hausdorff, Jeffrey, additional, Hopkinson, Nicholas S., additional, Hume, Emily, additional, Maetzler, Walter, additional, Micó-Amigo, Encarna M., additional, Palmerini, Luca, additional, Salis, Francesca, additional, Scott, Kirsty, additional, Troosters, Thierry, additional, Watz, Henrik, additional, Rochester, Lynn, additional, Del Din, Silvia, additional, Vogiatzis, Ioannis, additional, and Garcia-Aymerich, Judith, additional

Published
2023
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46. Clinical validation of real-world walking cadence in patients with COPD

Author

Delgado Ortiz, Laura, primary, Ranciati, Saverio, additional, Arbillaga-Etxarri, Ane, additional, Balcells, Eva, additional, Buekers, Joren, additional, Demeyer, Heleen, additional, Frei, Anja, additional, Gimeno-Santos, Elena, additional, Hopkinson, Nicholas S., additional, De Jong, Corina, additional, Karlsson, Niklas, additional, Palmerini, Luca, additional, Polkey, Michael I., additional, Puhan, Milo A., additional, Rabinovich, Roberto, additional, Rodríguez Chiaradia, Diego, additional, Rodriguez-Roisin, Robert, additional, Toran, Pere, additional, Vogiatzis, Ioannis, additional, Watz, Henrik, additional, Troosters, Thierry, additional, and Garcia-Aymerich, Judith, additional

Published
2023
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49. Estimating the Health and Economic Impact of Improved Management in Prevalent Chronic Obstructive Pulmonary Disease Populations in England, Germany, Canada, and Japan: A Modelling Study

Author

Adams, Elisabeth J, primary, van Doornewaard, Alexander, additional, Ma, Yixuan, additional, Ahmed, Nurilign, additional, Cheng, Man Ki, additional, Watz, Henrik, additional, Ichinose, Masakazu, additional, Wilkinson, Tom, additional, Bhutani, Mohit, additional, Licskai, Christopher J, additional, and Turner, Katy M E, additional

Published
2023
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