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Failure to adequately address language differences between home and school is one of the many ways in which education systems frequently disadvantage Aboriginal students. Children from predominantly Aboriginal English-speaking homes face specific challenges, as the language differences between their home variety and the Standard Australian English (SAE) of the curriculum and classroom are often rendered 'invisible', with little explicit accommodation to the fact that such children are essentially immersed into the SAE classroom (e.g. Dixon, 2013; McIntosh, O'Hanlon, & Angelo, 2012; Sellwood & Angelo, 2013). One consequence of this invisibility is that it has been very hard to see during classroom time, where these language differences appear to affect children's engagement with the curriculum. In this paper, we present a micro-analysis of a year 2 maths lesson in a class of Aboriginal learners of SAE as an additional language/dialect, where children are being taught to use location words (e.g. "under," "above") as mathematical language. We have examined the precise ways in which the children's home variety and SAE were used in this lesson, and where differences between these two varieties appeared to impact their understanding of the concepts being taught. We differentiate between the kinds of classroom language that provide a challenge to learners of SAE and the kinds that do not.

Background Antibacterial therapy is frequently used in patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) without evidence of bacterial infection, prompting concerns about increased antimicrobial resistance (AMR). We evaluated trends in AMR before and during the SARS-CoV-2 pandemic. Methods This multicenter, retrospective cohort analysis included hospitalized adults aged ≥18 years with >1-day inpatient admission and a record of discharge or death from 271 US facilities in the BD Insights Research Database. We evaluated rates of AMR events, defined as positive cultures for select gram-negative and gram-positive pathogens from any source, with nonsusceptibility reported by commercial panels before (1 July 2019–29 February 2020) and during (1 March 2020–30 October 2021) the SARS-CoV-2 pandemic. Results Of 5 518 666 admissions evaluated, AMR rates per 1000 admissions were 35.4 for the prepandemic period and 34.7 for the pandemic period (P ≤.0001). In the pandemic period, AMR rates per 1000 admissions were 49.2 for SARS-CoV-2–positive admissions, 41.1 for SARS-CoV-2–negative admissions, and 25.7 for patients untested (P ≤.0001). AMR rates per 1000 admissions among community-onset infections during the pandemic were lower versus prepandemic levels (26.1 vs 27.6; P <.0001), whereas AMR rates for hospital-onset infections were higher (8.6 vs 7.7; P <.0001), driven largely by SARS-CoV-2–positive admissions (21.8). AMR rates were associated with overall antimicrobial use, rates of positive cultures, and higher use of inadequate empiric therapy. Conclusions Although overall AMR rates did not substantially increase from prepandemic levels, patients tested for SARS-CoV-2 infection had a significantly higher rate of AMR and hospital-onset infections. Antimicrobial and diagnostic stewardship is key to identifying this high-risk AMR population. [ABSTRACT FROM AUTHOR]

Background Management of pneumococcal disease is complicated by high rates of antimicrobial resistance (AMR). This study assessed AMR trends for Streptococcus pneumoniae isolates from adults with pneumococcal disease. Methods From January 2011 to February 2020, we evaluated 30-day nonduplicate S. pneumoniae isolates from 290 US hospitals (BD Insights Research Database) from adults (≥18 years) in inpatient and outpatient settings. Isolates were required to have ≥1 AMR result for invasive (blood, cerebrospinal fluid/neurologic) or noninvasive (respiratory or ear/nose/throat) pneumococcal disease samples. Determination of AMR was based on facility reports of intermediate or resistant. Descriptive statistics and generalized estimated equations were used to assess variations over time. Results Over the study period, 34 039 S. pneumoniae isolates were analyzed (20 749 [61%] from noninvasive sources and 13 290 [39%] from invasive sources). Almost half (46.6%) of the isolates were resistant to ≥1 drug, and noninvasive isolates had higher rates of AMR than invasive isolates. Total S. pneumoniae isolates had high rates of resistance to macrolides (37.7%), penicillin (22.1%), and tetracyclines (16.1%). Multivariate modeling identified a significant increasing trend in resistance to macrolides (+1.8%/year; P  < .001). Significant decreasing trends were observed for penicillin (−1.6%/year; P  < .001), extended-spectrum cephalosporins (ESCs; −0.35%/year; P  < .001), and ≥3 drugs (−0.5%/year; P  < .001). Conclusions Despite decreasing trends for penicillin, ESCs, and resistance to ≥3 drugs, AMR rates are persistently high in S. pneumoniae isolates among US adults. Increasing macrolide resistance suggests that efforts to address AMR in S. pneumoniae may require antimicrobial stewardship efforts and higher-valent pneumococcal conjugate vaccines. [ABSTRACT FROM AUTHOR]

Discusses the technological changes that will necessitate the prospective conversion of library data over the next decade and addresses the problems of converting data from obsolete personal computers to newer models that feature radically different operating systems. Three case studies are used to illustrate possible scenarios. (11 references) (Author/CLB)