1. Carbapenemase-Producing Enterobacteriaceae and Nonfermentative Bacteria, the Philippines, 2013-2016.
- Author
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Velasco JM, Valderama MT, Peacock T, Warawadee N, Nogrado K, Navarro FC, Chua D Jr, Apichai S, Sirigade R, Macareo LR, and Swierczewski B
- Subjects
- Anti-Bacterial Agents pharmacology, Bacterial Proteins metabolism, Carbapenem-Resistant Enterobacteriaceae drug effects, Carbapenem-Resistant Enterobacteriaceae isolation & purification, Carbapenems pharmacology, Enterobacteriaceae Infections drug therapy, Enterobacteriaceae Infections microbiology, Gene Expression, Humans, Isoenzymes genetics, Isoenzymes metabolism, Microbial Sensitivity Tests, Multilocus Sequence Typing, Philippines epidemiology, Plasmids chemistry, Prevalence, Tertiary Care Centers, beta-Lactamases metabolism, Bacterial Proteins genetics, Carbapenem-Resistant Enterobacteriaceae genetics, Enterobacteriaceae Infections epidemiology, Plasmids metabolism, beta-Lactam Resistance genetics, beta-Lactamases genetics
- Abstract
During 2013-2016, we isolated bla
NDM - and blaVIM -harboring Enterobacteriaceae and nonfermentative bacteria from patients in the Philippines. Of 130 carbapenem-resistant isolates tested, 45 were Carba NP-positive; 43 harbored blaNDM , and 2 harbored blaVIM . Multidrug-resistant microbial pathogen surveillance and antimicrobial drug stewardship are needed to prevent further spread of New Delhi metallo-β-lactamase variants.- Published
- 2017
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