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2. A mathematical model for fluid-glucose-albumin transport in peritoneal dialysis

Author

Cherniha, R., Stachowska-Pietka, J., and Waniewski, J.

Subjects
Quantitative Biology - Tissues and Organs, Mathematics - Analysis of PDEs
Abstract

A mathematical model for fluid and solute transport in peritoneal dialysis is constructed. The model is based on a three-component nonlinear system of two-dimensional partial differential equations for fluid, glucose and albumin transport with the relevant boundary and initial conditions. Its aim is to model ultrafiltration of water combined with inflow of glucose to the tissue and removal of albumin from the body during dialysis, and it does this by finding the spatial distributions of glucose and albumin concentrations and hydrostatic pressure. The model is developed in one spatial dimension approximation and a governing equation for each of the variables is derived from physical principles. Under certain assumptions the model are simplified with the aim of obtaining exact formulae for spatially non-uniform steady-state solutions. As the result, the exact formulae for the fluid fluxes from blood to tissue and across the tissue are constructed together with two linear autonomous ODEs for glucose and albumin concentrations in the tissue. The obtained analytical results are checked for their applicability for the description of fluid-glucose-albumin transport during peritoneal dialysis., Comment: 28 pages, 8 figures. arXiv admin note: text overlap with arXiv:1110.1283

Published
2013
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9. CHANGES IN SUB-ENDOCARDIAL VIABILITY RATIO IN TRAUMATIC BRAIN INJURY PATIENTS

Author

Siwicka-Gieroba D, Robba C, Poleszczuk J, Debowska M, Waniewski J, Badenes R, Jaroszynski A, Piasek E, Kotfis K, Biernawska J, and Dabrowski W

Abstract

BACKGROUND: Traumatic brain injury is often associated with cardiac dysfunction, which is the consequence of the "brain-heart cross-talk". Sub-endocardial viability ratio (SEVR) is an estimate of myocardial perfusion. The aim of this study was to analyse the changes in SEVR in patients with severe TBI without previous cardiac diseases. METHODS: Adult patients treated for severe TBI with Glasgow Coma Score < 8 were studied. The pressure waveforms was obtained by a high-fidelity tonometer in the radial artery for SEVR calculation at the fife time points: immediately after the admission to ICU and 24, 48, 72 and 96 hours after the admission. SEVR and other clinically important parameters were analysed in patients who survived and non-survived after 28-days of treatment, as well as in patients who underwent decompressive craniectomy (DC). RESULTS: 64 patients (16 female and 48 male) aged 18 - 64 year were included. 50 patients survived and 14 died. Decompressive craniectomy was performed in 23 patients. SEVR decreased 24 hours after admission in non-survivors (p < 0.05) and after 48 hours in survivors (p < 0.01), and its values were significantly lower in non-survivors than in survivors at 24, 72 and 96 hours from admission (p < 0.05). SEVR increased following DC (p < 0.05). CONCLUSIONS: A decreased SEVR is observed in TBI patients. Surgical decompression increases SEVR indicating improvement in coronary microvascular perfusion. The results of our study seem to confirm that brain injury affects myocardium function.

Published
2021

11. Distributed model of peritoneal fluid absorption

Author

Stachowska-Pietka, J., Waniewski, J., Flessner, M.F., and Lindholm, B.

Subjects
Continuous ambulatory peritoneal dialysis -- Health aspects, Peritoneal dialysis -- Health aspects, Hydrostatic pressure -- Research, Biological sciences
Abstract

The process of water reabsorption from the peritoneal cavity into the surrounding tissue substantially decreases the net ultrafiltration in patients on peritoneal dialysis. The goal of this study was to propose a mathematical model based on data from clinical studies and animal experiments to describe the changes in absorption rate, interstitial hydrostatic pressure, and tissue hydration caused by increased intraperitoneal pressure after the initiation of peritoneal dialysis. The model describes water transport through a deformable, porous tissue after infusion of isotonic solution into the peritoneal cavity. Blood capillary and lymphatic vessels are assumed to be uniformly distributed within the tissue. Starling's law is applied for a description of fluid transport through the capillary wall, and the transport within the interstitium is modeled by Darcy's law. Transport parameters such as interstitial fluid volume ratio, tissue hydraulic conductance, and lymphatic absorption in the tissue are dependent on local interstitial pressure. Numerical simulations show the strong dependence of fluid absorption and tissue hydration on the values of intraperitoneal pressure. Our results predict that in the steady state only ~20-40% of the fluid that flows into the tissue from the peritoneal cavity is absorbed by the lymphatics situated in the tissue, whereas the larger (60-80%) part of the fluid is absorbed by the blood capillaries. water absorption; tissue transport; hydrostatic pressure; peritoneal dialysis

Published
2006

24. Phenotypic features of vascular calcification in chronic kidney disease

Author

Dai, L., primary, Debowska, M., additional, Lukaszuk, T., additional, Bobrowski, L., additional, Barany, P., additional, Söderberg, M., additional, Thiagarajan, D., additional, Frostegård, J., additional, Wennberg, L., additional, Lindholm, B., additional, Qureshi, A. R., additional, Waniewski, J., additional, and Stenvinkel, P., additional

Published
2019
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26. Phenotypic features of vascular calcification in chronic kidney disease.

Author

Dai, L., Debowska, M., Lukaszuk, T., Bobrowski, L., Barany, P., Söderberg, M., Thiagarajan, D., Frostegård, J., Wennberg, L., Lindholm, B., Qureshi, A. R., Waniewski, J., and Stenvinkel, P.

Subjects
CHRONIC kidney failure, KIDNEY calcification, KIDNEY exchange, ABSOLUTE value, BONE metabolism, CHRONICALLY ill
Abstract

Background: Patients with chronic kidney disease stage 5 (CKD5) are predisposed to vascular calcification (VC), but the combined effect of factors associated with VC was sparsely investigated. We applied the relaxed linear separability (RLS) feature selection model to identify features that concomitantly associate with VC in CKD5 patients.Methods: Epigastric arteries collected during surgery from living donor kidney transplant recipients were examined to score the histological extent of medial VC. Sixty-two phenotypic features in 152 patients were entered into RLS model to differentiate between no-minimal VC (n = 93; score 0-1) and moderate-extensive VC (n = 59; score 2-3). The subset of features associated with VC was selected on the basis of cross-validation procedure. The strength of association of the selected features with VC was expressed by the absolute value of 'RLS factor'.Results: Among 62 features, a subset of 17 features provided optimal prediction of VC with 89% of patients correctly classified into their groups. The 17 features included traditional risk factors (diabetes, age, cholesterol, BMI and male sex) and markers of bone metabolism, endothelial function, metabolites, serum antibodies and mitochondrial-derived peptide. Positive RLS factors range from 1.26 to 4.05 indicating features associated with increased risk of VC, and negative RLS factors range from -0.95 to -1.83 indicating features associated with reduced risk of VC.Conclusion: The RLS model identified 17 features including novel biomarkers and traditional risk factors that together concomitantly associated with medial VC. These results may inform further investigations of factors promoting VC in CKD5 patients. [ABSTRACT FROM AUTHOR]

Published
2020
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28. Exact Solutions of a Mathematical Model for Fluid Transport in Peritoneal Dialysis

Author

Cherniga, R.M. and Waniewski, J.

Subjects
Статті
Abstract

A mathematical model for fluid transport in peritoneal dialysis is constructed. The model is based on a nonlinear system of two-dimensional partial differential equations with corresponding boundary and initial conditions. Using the classical Lie scheme, we establish that the base system of partial differential equations (under some restrictions on coefficients) is invariant under the infinite-dimensional Lie algebra, which enables us to construct families of exact solutions. Moreover, exact solutions with a more general structure are found using another (non-Lie) technique. Finally, it is shown that some of the solutions obtained describe the hydrostatic pressure and the glucose concentration in peritoneal dialysis. Побудовано математичну модель переносу рідини при очеревинному діалізі, яка базується на нелінійній системі двовимірних диференціальних рівнянь з частинними похідними (ДРЧП) з відповідними крайовими та початковими умовами. Шляхом застосування класичного методу Лі встановлено, що базова система ДРЧП (при певних обмеженнях на коефіцієнти) інваріантна відносно нескінченновимірної алгебри Лі, що дозволило побудувати сім'ї точних розв'язків. Крім того, точні розв'язки більш загальної структури знайдено за допомогою іншого неліївського методу. Також встановлено, що деякі з отриманих розв'язків описують гідростатичний тиск та концентрацію глюкози при очеревинному діалізі.

Published
2005

30. DIALYSIS. PATHOPHYSIOLOGY AND CLINICAL STUDIES

Author

Humalda, J. K., primary, Assa, S., additional, Navis, G. J., additional, Franssen, C. F. M., additional, De Borst, M. H., additional, Ogawa, H., additional, Ota, Y., additional, Watanabe, T., additional, Watanabe, Y., additional, Nishii, H., additional, Sato, A., additional, Waniewski, J., additional, Debowska, M., additional, Wojcik-Zaluska, A., additional, Ksiazek, A., additional, Zaluska, W., additional, Guastoni, C. M., additional, Turri, C., additional, Toma, L., additional, Rombola, G., additional, Frattini, G., additional, Romei Longhena, G., additional, Teatini, U., additional, Siriopol, D.-C., additional, Stuard, S., additional, Ciolan, A., additional, Mircescu, G., additional, Raluca, D., additional, Nistor, I., additional, Covic, A., additional, De Roij Van Zuijdewijn, C. L., additional, Chapdelaine, I., additional, Nube, M. J., additional, Blankestijn, P. J., additional, Bots, M. L., additional, Konings, S. J., additional, Van Den Dorpel, M. A., additional, Van Der Weerd, N. C., additional, Ter Wee, P. M., additional, Grooteman, M. P., additional, Djuric, P. S., additional, Jankovic, A., additional, Tosic, J., additional, Bajcetic, S., additional, Damjanovic, T., additional, Popovic, J., additional, Dimkovic, N., additional, Marinkovic, J., additional, Djuric, Z., additional, Knezevic, V., additional, Lazarevic, T., additional, Ljubenovic, S., additional, Markovic, R., additional, Rabrenovic, V., additional, Djukanovic, L., additional, Radovic Maslarevic, V., additional, Mathrani, V., additional, Drew, P., additional, Chess, J. I., additional, Williams, A. I., additional, Robertson, S., additional, Jibani, M., additional, Aithal, V. I., additional, Kumwenda, M., additional, Roberts, G., additional, Mikhail, A. I., additional, Grzegorzewska, A. E., additional, Ostromecki, G., additional, Mostowska, A., additional, Sowi ska, A., additional, Jagodzi ski, P. P., additional, Wu, H.-Y., additional, Chen, H.-Y., additional, Hsu, S.-P., additional, Pai, M.-F., additional, Yang, J.-Y., additional, Peng, Y.-S., additional, Hirose, M., additional, Hasegawa, T., additional, Kaneshima, N., additional, Sasai, F., additional, Komukai, D., additional, Takahashi, K., additional, Koiwa, F., additional, Shishido, K., additional, Yoshimura, A., additional, Selim, G., additional, Stojceva-Taneva, O., additional, Tozija, L., additional, Dzekova-Vidimliski, P., additional, Trajceska, L., additional, Petronievic, Z., additional, Gelev, S., additional, Amitov, V., additional, Sikole, A., additional, Moon, S. J., additional, Yoon, S. Y., additional, Shin, D. H., additional, Lee, J. E., additional, Kim, H.-J., additional, Park, H.-C., additional, Hadjiyannakos, D., additional, Filiopoulos, V., additional, Loukas, G., additional, Pagonis, S., additional, Andriopoulos, C., additional, Drakou, A., additional, Vlassopoulos, D., additional, Catarino, C., additional, Cunha, P., additional, Ribeiro, S., additional, Rocha-Pereira, P., additional, Reis, F., additional, Sameiro-Faria, M., additional, Miranda, V., additional, Bronze-Rocha, E., additional, Belo, L., additional, Costa, E., additional, Santos-Silva, A., additional, De Mauri, A., additional, Brambilla, M., additional, Chiarinotti, D., additional, Lizio, D., additional, Matheoud, R., additional, Conti, N., additional, Conte, M. M., additional, Carriero, A., additional, De Leo, M., additional, Karpetas, A. V., additional, Sarafidis, P. A., additional, Georgianos, P. I., additional, Koutroumpas, G., additional, Divanis, D., additional, Vakianis, P., additional, Tzanis, G., additional, Raptopoulou, K., additional, Protogerou, A., additional, Stamatiadis, D., additional, Syrganis, C., additional, Liakopoulos, V., additional, Efstratiadis, G., additional, Lasaridis, A. N., additional, Tersi, M., additional, Stamatiadis, D. N., additional, Kuczera, P., additional, Adamczak, M., additional, Wiecek, A., additional, Bove, S., additional, Giacon, B., additional, Corradini, R., additional, Prati, E., additional, Brognoli, M., additional, Tommasi, A., additional, Sereni, L., additional, Palladino, G., additional, Moriya, H., additional, Mochida, Y., additional, Ishioka, K., additional, Oka, M., additional, Maesato, K., additional, Hidaka, S., additional, Ohtake, T., additional, Kobayashi, S., additional, Moura, A., additional, Madureira, J., additional, Alija, P., additional, Fernandes, J. C., additional, Oliveira, J. G., additional, Lopez, M., additional, Filgueiras, M., additional, Amado, L., additional, Vieira, M., additional, Seok, J.-H., additional, Choi, H. Y., additional, Ha, S. K., additional, Park, H. C., additional, Bossola, M., additional, Laudisio, A., additional, Antocicco, M., additional, Tazza, L., additional, Colloca, G., additional, Tosato, M., additional, Zuccala, G., additional, Ettema, E. M., additional, Kuipers, J., additional, Groen, H., additional, Gansevoort, R. T., additional, Stade, K., additional, Bakker, S. J. L., additional, Gaillard, C. A. J. M., additional, Westerhuis, R., additional, Bacchetta, J., additional, Couchoud, K., additional, Semlali, S., additional, Sellier-Leclerc, A.-L., additional, Bertholet-Thomas, A., additional, Cartier, R., additional, Cochat, P., additional, Ranchin, B., additional, Kim, J. C., additional, Park, K., additional, Van Ende, C., additional, Wilmes, D., additional, Lecouvet, F. E., additional, Labriola, L., additional, Cuvelier, R., additional, Van Ingelgem, G., additional, Jadoul, M., additional, Doriana, C., additional, David, P., additional, Capurro, F., additional, Brustia, M., additional, Ruva, C. E., additional, Giungi, S., additional, Di Stasio, E., additional, Lemesch, S., additional, Leber, B., additional, Horvath, A., additional, Ribitsch, W., additional, Schilcher, G., additional, Zettel, G., additional, Tawdrous, M., additional, Rosenkranz, A. R., additional, Stadlbauer-Kollner, V., additional, Matsushima, H., additional, Oyama, A., additional, Bosch Benitez-Parodi, E., additional, Baamonde Laborda, E., additional, Batista Garcia, F., additional, Perez Suarez, G., additional, Anton Perez, G., additional, Garcia Canton, C., additional, Toledo Gonzalez, A., additional, Lago Alonso, M. M., additional, Checa Andres, M. D., additional, Cobo, G., additional, Di Gioia, C., additional, Camacho, R., additional, Garcia Lacalle, C., additional, Ortega, O., additional, Rodriguez, I., additional, Herrero, J., additional, Oliet, A., additional, Ortiz, M., additional, Mon, C., additional, Vigil, A., additional, Gallar, P., additional, Pellu, V., additional, Nebiolo, P. E., additional, Sasaki, K., additional, Yamguchi, S., additional, Hesaka, A., additional, Iwahashi, E., additional, Sakai, S., additional, Fujimoto, T., additional, Minami, S., additional, Fujita, Y., additional, Yokoyama, K., additional, Shutov, E., additional, Ryabinskya, G., additional, Lashutin, S., additional, Gorelova, E., additional, Volodicheva, E., additional, Podesta, M. A., additional, Cancarini, G., additional, Cucchiari, D., additional, Montanelli, A., additional, Badalamenti, S., additional, Graziani, G., additional, Distasio, E., additional, Pchelin, I., additional, Shishkin, A., additional, Fedorova, Y., additional, Kao, C.-C., additional, Chu, T.-S., additional, Tsai, T.-J., additional, Wu, K.-D., additional, Wu, M.-S., additional, Raikou, V., additional, Kaisidis, P., additional, Tsamparlis, E., additional, Kanellopoulos, P., additional, Boletis, J., additional, Ueda, A., additional, Hirayama, A., additional, Owada, S., additional, Nagai, K., additional, Saito, C., additional, and Yamagata, K., additional

Published
2014
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31. DIALYSIS BONE DISEASE

Author

Fusaro, M., primary, Giannini, S., additional, Miozzo, D., additional, Noale, M., additional, Tripepi, G., additional, Plebani, M., additional, Zaninotto, M., additional, Piccoli, A., additional, Vilei, M. T., additional, Cristofaro, R., additional, Gallieni, M., additional, Hamamoto, K., additional, Inaba, M., additional, Okuno, S., additional, Imanishi, Y., additional, Ishimura, E., additional, Yamakawa, T., additional, Shoji, S., additional, Rothe, H. M., additional, Eller, P., additional, Mayer, G., additional, Ketteler, M., additional, Kramar, R., additional, Shaheen, F., additional, Al Rukhaimi, M., additional, Alsahow, A., additional, Al-Ali, F., additional, Al Salmi, I., additional, Al Ghareeb, S., additional, Wang, M., additional, Bieber, B., additional, Robinson, B. M., additional, Pisoni, R. L., additional, Waniewski, J., additional, Debowska, M., additional, Wojcik-Zaluska, A., additional, Ksiazek, A., additional, Zaluska, W., additional, De Broe, M. E., additional, Wilson, R. J., additional, Copley, J. B., additional, Hiramtasu, R., additional, Ubara, Y., additional, Hoshino, J., additional, Takaichi, K., additional, Ghalli, F. G., additional, Ibakkanavar, R., additional, Chess, J., additional, Roberts, G., additional, Riley, S., additional, Oliveira, A. S. A., additional, Carvalho, C. J. B., additional, Oliveira, C. B. L., additional, Pessoa, C. T. B. C., additional, Leao, R. A. S., additional, Gueiros, J. E. B., additional, Gueiros, A. P. S., additional, Okano, K., additional, Tsuruta, Y., additional, Hibi, A., additional, Tsukada, M., additional, Miwa, N., additional, Kimata, N., additional, Tsuchiya, K., additional, Akiba, T., additional, Nitta, K., additional, Mizobuchi, M., additional, Ogata, H., additional, Hosaka, N., additional, Sanada, D., additional, Arai, N., additional, Koiwa, F., additional, Kinugasa, E., additional, Shibata, T., additional, Akizawa, T., additional, Delanaye, P., additional, Krzesinski, J.-M., additional, Warling, X., additional, Moonen, M., additional, Smelten, N., additional, Medart, L., additional, Pottel, H., additional, Cavalier, E., additional, Souberbielle, J.-C., additional, Gadisseur, R., additional, Dubois, B. E., additional, Matias, P., additional, Jorge, C., additional, Mendes, M., additional, Azevedo, A., additional, Navarro, D., additional, Ferreira, C., additional, Amaral, T., additional, Aires, I., additional, Gil, C., additional, Ferreira, A., additional, Kikuchi, H., additional, Shimada, H., additional, Karasawa, R., additional, Suzuki, M., additional, An, W. S., additional, Lee, S. M., additional, Oh, Y. J., additional, Son, Y. K., additional, De Paola, L., additional, Lombardi, G., additional, Panzino, M. T., additional, Lombardi, L., additional, Reichel, H., additional, Hahn, K.-M., additional, Kohnle, M., additional, Guggenberger, C., additional, Delanna, F., additional, Sasaki, N., additional, Tsunoda, M., additional, Ikee, R., additional, Hashimoto, N., additional, Sola, L., additional, Leyun, M. N., additional, Diaz, J. C., additional, Sehabiague, C., additional, Gonzalez, S., additional, Alallon, W., additional, Bourbeau, K., additional, Lajoie, C., additional, Macway, F., additional, Fujii, T., additional, Suzuki, S., additional, Shinozaki, M., additional, Tanaka, H., additional, Klingele, M., additional, Seiler, S., additional, Poppleton, A., additional, Lepper, P., additional, Fliser, D., additional, Seidel, R., additional, Lun, L., additional, Liu, D., additional, Li, X., additional, Wei, X., additional, Miao, J., additional, Gao, Z., additional, Hu, R., additional, Gros, B., additional, Galan, A., additional, Gonzalez-Parra, E., additional, Herrero, J. A., additional, Echave, M., additional, Vegter, S., additional, Tolley, K., additional, Oyaguez, I., additional, Gutzwiller, F. S., additional, Braunhofer, P. G., additional, Szucs, T. D., additional, Schwenkglenks, M., additional, Yilmaz, V. T., additional, Ozdem, S., additional, Donmez, L., additional, Kocak, H., additional, Dinckan, A., additional, Cetinkaya, R., additional, Suleymanlar, G., additional, and Ersoy, F. F., additional

Published
2014
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32. Changes in circulating biomarkers during a single hemodialysis session

Author

Yamamoto, T., Nascimento, M. M., Hayashi, Shirley Y., Qureshi, A. R., Waniewski, J., Brodin, L. A., Anderstam, B., Lind, B., Riella, M. C., Seeberger, A., Lindholm, B., Yamamoto, T., Nascimento, M. M., Hayashi, Shirley Y., Qureshi, A. R., Waniewski, J., Brodin, L. A., Anderstam, B., Lind, B., Riella, M. C., Seeberger, A., and Lindholm, B.

Abstract

The hemodialysis (HD) procedure induces an inflammatory response potentially contributing to cardiovascular disease. Here we investigated the acute impact of HD on circulating biomarkers. Circulating biomarkers (small solutes, middle molecular-sized peptides, and proteins) related to inflammation, oxidative stress, and vascular calcification (VC) were measured before and after a single session of HD in 45 clinically stable patients. Concentrations were corrected for ultrafiltration-induced hemoconcentration. Among vascular calcification-related biomarkers, osteoprotegerin and fetuin-A remained unchanged while fibroblast growth factor-23 (FGF23) decreased by -19%. Changes of FGF23 and changes of phosphate correlated (ρ=0.61, P<0.001). While C-reactive protein did not change, interleukin-6 (IL-6) increased by 14% and pentraxin 3 (PTX3) increased by 45%. IL-6 and PTX3 appear to be valid biomarkers of the intradialytic inflammatory response. VC-related markers were in general not affected by the single HD session; however, the observed correlation between acute changes of FGF-23 and phosphate during HD warrants further studies., QC 20130212

Published
2013
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33. Mathematical Modeling of Antigen and Immune Complex Kinetics during Extracorporeal Removal of Autoantibody

Author

Weryński A and Waniewski J

Subjects
030232 urology & nephrology, Biomedical Engineering, Medicine (miscellaneous), Bioengineering, Antigen-Antibody Complex, 030204 cardiovascular system & hematology, Extracorporeal, Biomaterials, 03 medical and health sciences, 0302 clinical medicine, Immune system, Antigen, Myasthenia Gravis, medicine, Humans, Autoantibodies, Plasma Exchange, biology, Chemistry, Catabolism, Autoantibody, General Medicine, Models, Theoretical, medicine.disease, Myasthenia gravis, Immune complex, Immunology, biology.protein, Drainage, Lymph, Antibody
Abstract

The extracorporeal removal of circulating auto-antibodies by repeated plasma exchange or continuous lymph drainage is modeled by single-pool kinetics. Total amounts of antigenic determinants, k-valent antibodies and immune complexes are variables of the model. Factors influencing the course of therapy are included: production rate of antigen and antibody and their natural catabolism. This model can give useful formulae for clinical practice. The effect of treatment can be predicted from the relative depletion of antibody and the actual severity of the disease. Another formula shows how the changed catabolism of antigen after antibody binding can influence the amount of immune complexes. As an example, lymph drainage in myasthenia gravis is calculated using averaged data from three patients.

Published
1991
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34. Peritoneal dialysis - A

Author

Ito, M., primary, Emami-Naini, A., additional, Keyvandarian, N., additional, Moeinzadeh, F., additional, Mortazavi, M., additional, Taheri, S., additional, Io, K., additional, Nishino, T., additional, Obata, Y., additional, Kitamura, M., additional, Abe, S., additional, Koji, T., additional, Kohno, S., additional, Wakabayashi, K., additional, Hamada, C., additional, Nakano, T., additional, Kanda, R., additional, Io, H., additional, Horikoshi, S., additional, Tomino, Y., additional, Korte, M. R., additional, Braun, N., additional, Habib, S. M., additional, Goffin, E., additional, Summers, A., additional, Heuveling, L., additional, Betjes, M. G. H., additional, Lambie, M., additional, Bankart, J., additional, Johnson, D., additional, Mactier, R., additional, Phillips-Darby, L., additional, Topley, N., additional, Davies, S., additional, Liu, F. X., additional, Leipold, R., additional, Arici, M., additional, Farooqui, U., additional, Cho, K.-h., additional, Do, J.-y., additional, Kang, S.-h., additional, Park, J.-W., additional, Yoon, K.-W., additional, Jung, S.-Y., additional, Sise, C., additional, Rutherford, P., additional, Kovacs, L., additional, Konings, S., additional, Pestana, M., additional, Zimmermann, J., additional, Cramp, H., additional, Stein, D., additional, Bang, K., additional, Shin, J. H., additional, Jeong, J., additional, Kim, J.-H., additional, Matsuo, N., additional, Maruyama, Y., additional, Nakao, M., additional, Tanno, Y., additional, Ohkido, I., additional, Hayakawa, H., additional, Yamamoto, H., additional, Yokoyama, K., additional, Hosoya, T., additional, Iannuzzella, F., additional, Corradini, M., additional, Belloni, L., additional, Stefani, A., additional, Parmeggiani, M., additional, Pasquali, S., additional, Svedberg, O., additional, Stenvinkel, P., additional, Qureshi, A. R., additional, Barany, P., additional, Heimburger, O., additional, Leurs, P., additional, Anderstam, B., additional, Waniewski, J., additional, Antosiewicz, S., additional, Baczynski, D., additional, Galach, M., additional, Wankowicz, Z., additional, Prabhu, M., additional, Subhramanyam, S. V., additional, Nayak, K. S., additional, Hwang, J.-C., additional, Jiang, M.-Y., additional, Lu, Y.-H., additional, Wang, C.-T., additional, Santos, C., additional, Rodriguez-Carmona, A., additional, Perez Fontan, M., additional, Schaefer, B., additional, Macher-Goeppinger, S., additional, Bayazit, A., additional, Sallay, P., additional, Testa, S., additional, Holland-Cunz, S., additional, Querfeld, U., additional, Warady, B. A., additional, Schaefer, F., additional, Schmitt, C. P., additional, Guney, I., additional, Turkmen, K., additional, Yazici, R., additional, Aslan, S., additional, Altintepe, L., additional, Yeksan, M., additional, Kocyigit, I., additional, Sipahioglu, M., additional, Orscelik, O., additional, Unal, A., additional, Celik, A., additional, Abbas, S., additional, Zhu, F., additional, Tokgoz, B., additional, Dogan, A., additional, Oymak, O., additional, Kotanko, P., additional, Levin, N., additional, Sanchez-Gonzalez, M. C., additional, Gonzalez-Casaus, M. L., additional, Gonzalez-Parra, E., additional, Albalate, M., additional, Lorenzo, V., additional, Torregrosa, V., additional, Fernandez, E., additional, de la Piedra, C., additional, Rodriguez, M., additional, Zeiler, M., additional, Monteburini, T., additional, Agostinelli, R. M., additional, Marinelli, R., additional, Santarelli, S., additional, Bermond, F., additional, Bagnis, C., additional, Marcuccio, C., additional, Soragna, G., additional, Bruno, M., additional, Vitale, C., additional, Marangella, M., additional, Martino, F., additional, Scalzotto, E., additional, Rodighiero, M. P., additional, Crepaldi, C., additional, Ronco, C., additional, Seferi, S., additional, Rroji, M., additional, Likaj, E., additional, Barbullushi, M., additional, Thereska, N., additional, Kim, E. J., additional, Han, J. H., additional, Koo, H. M., additional, Doh, F. M., additional, Kim, C. H., additional, Ko, K. I., additional, Lee, M. J., additional, Oh, H. J., additional, Han, S. H., additional, Yoo, T.-H., additional, Choi, K. H., additional, Kang, S.-W., additional, Uzun, S., additional, Karadag, S., additional, Yegen, M., additional, Gursu, M., additional, Ozturk, S., additional, Aydin, Z., additional, Sumnu, A., additional, Cebeci, E., additional, Atalay, E., additional, Kazancioglu, R., additional, Alscher, D., additional, Fritz, P., additional, Latus, J., additional, Kimmel, M., additional, Biegger, D., additional, Lindenmeyer, M., additional, Cohen, C. D., additional, Wuthrich, R. P., additional, Segerer, S., additional, Kim, Y. K., additional, Kim, H. W., additional, Song, H. C., additional, Choi, E. J., additional, Yang, C. W., additional, Matsuda, A., additional, Tayama, Y., additional, Ogawa, T., additional, Iwanaga, M., additional, Okazaki, S., additional, Hatano, M., additional, Kiba, T., additional, Shimizu, T., additional, Hasegawa, H., additional, Mitarai, T., additional, Dratwa, M., additional, Collart, F., additional, Verger, C., additional, Takayanagi, K., additional, Iwashita, T., additional, Noiri, C., additional, Inamura, M., additional, Nakamura, S., additional, Kato, H., additional, Sipahioglu, M. H., additional, Elmali, F., additional, Zhang, X., additional, Ma, J., additional, Giuliani, A., additional, Blanca-Martos, L., additional, Nayak Karopadi, A., additional, Mason, G., additional, Santos, M. T., additional, Fonseca, I., additional, Santos, O., additional, Rocha, M. J., additional, Carvalho, M. J., additional, Cabrita, A., additional, Rodrigues, A., additional, Scabbia, L., additional, Domenici, A., additional, Apponi, F., additional, Tayefeh Jafari, M., additional, Sivo, F., additional, Falcone, C., additional, Punzo, G., additional, Mene, P., additional, Yildirim, T., additional, Yilmaz, R., additional, Azak, A., additional, Altindal, M., additional, Turkmen, E., additional, Altun, B., additional, Duranay, M., additional, Erdem, Y., additional, Buyukbakkal, M., additional, Eser, B., additional, Yayar, O., additional, Ercan, Z., additional, Kali, A., additional, Erdogan, B., additional, Haspulat, A., additional, Merhametsiz, O., additional, Ulusal-Okyay, G., additional, Akdag, S. I., additional, Ayli, M. D., additional, Pietrzycka, A., additional, Miarka, P., additional, Chowaniec, E., additional, Sulowicz, W., additional, Lutwin, M., additional, Gaska, M., additional, and Paciorek, A., additional

Published
2013
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35. Extracorporeal dialysis: techniques and adequacy - A

Author

Steckiph, D., primary, Calabrese, G., additional, Bertucci, A., additional, Mazzotta, A., additional, Vagelli, G., additional, Gonella, M., additional, Stamopoulos, D., additional, Manios, E., additional, Papachristos, N., additional, Grapsa, E., additional, Papageorgiou, G., additional, Gogola, V., additional, So, B., additional, Dey, V., additional, Spalding, E. M., additional, Libetta, C., additional, Esposito, P., additional, Margiotta, E., additional, Maffioli, P., additional, Bonaventura, A., additional, Bianchi, L., additional, Romano, D., additional, Rampino, T., additional, De Rosa, G., additional, Mauric, A., additional, Haug, U., additional, Enzinger, G., additional, Kern-Derstvenscheg, E., additional, Sluga, A., additional, Ausserwinkler, C., additional, Beck, W., additional, Rosenkranz, A. R., additional, Maheshwari, V., additional, Haroon, S., additional, Loy, Y., additional, Samavedham, L., additional, Rangaiah, G. P., additional, Lau, T., additional, Mpakirtzi, N., additional, Panagiotou, M., additional, Barbarousi, D., additional, Matsouka, C., additional, Bunani, A. D., additional, Kowalczyk, M., additional, Bartnicki, P., additional, Banach, M., additional, Rysz, J., additional, Lentini, P., additional, Zanoli, L., additional, Granata, A., additional, Contestabile, A., additional, Basso, A., additional, Berlingo, G., additional, Pellanda, V., additional, de Cal, M., additional, Grazia, V., additional, Clementi, A., additional, Insalaco, M., additional, Dell'Aquila, R., additional, Karkar, A., additional, Abdelrahman, M., additional, Martins, A. R., additional, Parreira, L., additional, Duque, A. S., additional, Rodrigues, I., additional, Baffoun, A. B., additional, Youssfi, M. A., additional, Sayeh, A., additional, Beji, M., additional, Ben Khadra, R., additional, Hmida, J., additional, Akazawa, M., additional, Horiuchi, H., additional, Hori, Y., additional, Yamada, A., additional, Satou, H., additional, Odamaki, S., additional, Nakai, S., additional, Satou, K., additional, Aoki, K., additional, Saito, I., additional, Kamijo, Y., additional, Ogata, S., additional, Ishibashi, Y., additional, Basso, F., additional, Wojewodzka-Zelezniakowicz, M., additional, Cruz, D., additional, Giuliani, A., additional, Blanca Martos, L., additional, Piccinni, P., additional, Ronco, C., additional, Potier, J., additional, Queffeulou, G., additional, Bouet, J., additional, Nilsson, A., additional, Sternby, J., additional, Grundstrom, G., additional, Alquist, M., additional, Ferraresi, M., additional, Di Vico, M. C., additional, Vigotti, F. N., additional, Deagostini, M., additional, Scognamiglio, S., additional, Consiglio, V., additional, Clari, R., additional, Moro, I., additional, Mongilardi, E., additional, Piccoli, G. B., additional, Hancock, V., additional, Huang, S., additional, Nilsson Ekdahl, K., additional, Steckiph, D., additional, Baldin, C., additional, Petrarulo, M., additional, Mancuso, D., additional, Inguaggiato, P., additional, Canepari, G., additional, Gigliola, G., additional, Ferrando, C., additional, Meinero, S., additional, Sicuso, C., additional, Pacitti, A., additional, Afentakis, N., additional, Tomo, T., additional, Matsuyama, K., additional, Nakata, T., additional, Ishida, K., additional, Takeno, T., additional, Kadota, J.-i., additional, Minakuchi, J., additional, Kastl, J., additional, Merello, M., additional, Boccato, C., additional, Giordana, G., additional, Mazzone, S., additional, Moscardo, V., additional, Reinhardt, B., additional, Knaup, R., additional, Kruger, W., additional, Tovbin, D., additional, Kim, S., additional, Avnon, L., additional, Zlotnik, M., additional, Storch, S., additional, Umimoto, K., additional, Shimamoto, Y., additional, Suyama, M., additional, Miyata, M., additional, Bosch Benitez-Parodi, E., additional, Baamonde Laborda, E. E., additional, Perez, G., additional, Ramirez, J. I., additional, Ramirez Puga, A., additional, Guerra, R., additional, Garcia Canton, C., additional, Lago Alonso, M. M., additional, Toledo, A., additional, Checa Andres, M. D., additional, Latif, F. E., additional, Mochida, Y., additional, Matsumoto, K., additional, Morita, K., additional, Tsutsumi, D., additional, Ishioka, K., additional, Maesato, K., additional, Oka, M., additional, Moriya, H., additional, Hidaka, S., additional, Ohtake, T., additional, Kobayashi, S., additional, Ficheux, A., additional, Gayrard, N., additional, Duranton, F., additional, Guzman, C., additional, Szwarc, I., additional, Bismuth-Mondolfo, J., additional, Brunet, P., additional, Servel, M.-F., additional, Argiles, A., additional, Tsikliras, N., additional, Mademtzoglou, S., additional, Balaskas, E., additional, Zeid, M., additional, Mostafa, A., additional, Mowafy, M. N., additional, Abdo, E. I., additional, Al Amin, O. M., additional, Ksiazek, A., additional, Zaluska, W., additional, Waniewski, J., additional, Debowska, M., additional, Wojcik-Zaluska, A., additional, Elias, M., additional, Francois, H., additional, Obada, E., additional, Lorenzo, H. K., additional, Charpentier, B., additional, Durrbach, A., additional, Beaudreuil, S., additional, Imamovic, G., additional, Marcelli, D., additional, Bayh, I., additional, Hrvacevic, R., additional, Kapun, S., additional, Grassmann, A., additional, Scatizzi, L., additional, Maslovaric, J., additional, Daelemans, R., additional, Mesens, S., additional, Mohamed, E. A., additional, Wafae, A., additional, Kawtar, H., additional, Mohamed Amine, H., additional, Driss, K., additional, and Mohammed, B., additional

Published
2013
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37. Extracorporeal dialysis: techniques and adequacy

Author

Passalacqua, S., primary, Staffolani, E., additional, Brescia, P., additional, Loschiavo, C., additional, Mancini, E., additional, Monaci, G., additional, Russo, G. E., additional, Ramunni, A., additional, Granger Vallee, A., additional, Chenine, L., additional, Leray-Moragues, H., additional, Gontier-Picard, A., additional, Rodriguez, A., additional, Chalabi, L., additional, Canaud, B., additional, Lantz, B., additional, Kapke, A., additional, Pearson, J., additional, Vanholder, R., additional, Tomo, T., additional, Robinson, B., additional, Port, F., additional, Daugirdas, J., additional, Ramirez, S., additional, Akonur, A., additional, Agar, B. U., additional, Culleton, B. F., additional, Gellens, M. E., additional, Leypoldt, J. K., additional, Troidle, L., additional, Finkelstein, F. O., additional, Kohn, O. F., additional, Basile, C., additional, Libutti, P., additional, Di Turo, A. L., additional, Casucci, F., additional, Losurdo, N., additional, Teutonico, A., additional, Vernaglione, L., additional, Lomonte, C., additional, Umimoto, K., additional, Nata, Y., additional, Shimamoto, Y., additional, Miyata, M., additional, Krisp, C., additional, Gmerek, A., additional, Wagner, J., additional, Wolters, D., additional, Pedrini, L. A., additional, Kopec, J., additional, Sulowicz, W., additional, Falkenhagen, D., additional, Thijssen, S., additional, Brandl, M., additional, Hartmann, J., additional, Strobl, K., additional, Wallner, M., additional, Mahieu, E., additional, Verhamme, P., additional, Op De Beeck, K., additional, Kuypers, D., additional, Claes, K., additional, Vitale, C., additional, Bagnis, C., additional, Berutti, S., additional, Soragna, G., additional, Gabella, P., additional, Fruttero, C., additional, Marangella, M., additional, Khadzhynov, D., additional, Baumann, C., additional, Lieker, I., additional, Slowinski, T., additional, Neumayer, H.-H., additional, Peters, H., additional, Bibiano, L., additional, Freddi, P., additional, Ricciatti, A., additional, Sagripanti, S., additional, Manarini, G., additional, Frasca, G. M., additional, Hwang, K. S., additional, Park, J.-S., additional, Lee, C. H., additional, Kang, C. M., additional, Kim, G.-H., additional, Urabe, S., additional, Kokubo, K., additional, Tsukao, H., additional, Shimbo, T., additional, Hirose, M., additional, Kobayashi, H., additional, Itoh, Y., additional, Kikuchi, K., additional, Murakami, K., additional, Tsuruta, Y., additional, Niwa, T., additional, Masakane, I., additional, Esashi, S., additional, Igarashi, H., additional, Djogan, M., additional, Boltina, I., additional, Dudar, I., additional, Pastori, G., additional, Favaro, E., additional, Ferraro, A., additional, Marcon, R., additional, Guizzo, M., additional, Lazzarin, R., additional, Conte, F., additional, Nichelatti, M., additional, Limido, A., additional, Zhu, F., additional, Liu, L., additional, Kaysen, G. A., additional, Abbas, S. R., additional, Kotanko, P., additional, Levin, N. W., additional, Debska-Slizien, A., additional, Malgorzewicz, S., additional, Dudziak, M., additional, Rutkowski, B., additional, Svojanovsky, J., additional, Dob ak, P., additional, Nedbalkova, M., additional, Reichertova, A., additional, Soucek, M., additional, Kirmizis, D., additional, Kougioumtzidou, O., additional, Vakianis, P., additional, Papagianni, A., additional, Sestigiani, E., additional, Gissara, Z., additional, Palladino, G., additional, Santoro, A., additional, Schneditz, D., additional, Stockinger, J., additional, Ribitsch, W., additional, Branco, P., additional, Figueiredo, S., additional, Santana, S., additional, Rocha, C., additional, Carvalho, L., additional, Borges, S., additional, Marques, D., additional, Barata, D., additional, Matsuyama, M., additional, Matsuyama, K., additional, Matsuyama, I., additional, Minakuchi, J., additional, Schiffl, H., additional, Fischer, R., additional, Lang, S., additional, de los Santos, C. A., additional, Antonello, I. C., additional, Poli-de-Figueiredo, C. E., additional, d'Avila, D., additional, Rosales, L., additional, Ulloa, D., additional, Carter, M., additional, Umehara, S., additional, Sakai, K., additional, Krieter, D. H., additional, Seidel, S., additional, Merget, K., additional, Lemke, H.-D., additional, Morgenroth, A., additional, Wanner, C., additional, Onogi, T., additional, Nishida, Y., additional, Ueno, J., additional, Taoka, M., additional, Sato, T., additional, Sakurai, K., additional, Saito, T., additional, Yamauchi, F., additional, Asahi, D., additional, Hosoya, H., additional, Maruyama, N., additional, Suzuki, A., additional, Alain, R., additional, Christian, D., additional, Romano, J.-M., additional, Printz, J., additional, Philippe, B., additional, Micha, T., additional, Hadjiyannakos, D., additional, Pani, I., additional, Sonikian, M., additional, Karatzas, I., additional, Vlassopoulos, D., additional, Kanaki, A., additional, Caprioli, R., additional, Lippi, A., additional, Donadio, C., additional, Malliekal, S., additional, Kubey, W., additional, Bernardo, A. A., additional, Katzarski, K., additional, Galach, M., additional, Waniewski, J., additional, Sambale, S., additional, Reising, A., additional, Donnerstag, F., additional, Hafer, C., additional, Schmidt, B., additional, Kielstein, J. T., additional, Ervo, R., additional, Angeletti, S., additional, Turrini Dertenois, L., additional, Cavatorta, F., additional, Gondouin, B., additional, Bevins, A., additional, Cockwell, P., additional, Hutchison, C. A., additional, Doria, M., additional, Genovesi, S., additional, Biagi, F., additional, Grandi, F., additional, Frontini, A., additional, Stella, A., additional, Cases, A., additional, Fort, J., additional, Maduell, F., additional, Comas, J., additional, Arcos, E., additional, Deulofeu, R., additional, Rroji (Molla), M., additional, Seferi, S., additional, Barbullushi, M., additional, Spahia, N., additional, Likaj, E., additional, Thereska, N., additional, Morena, M., additional, Jaussent, I., additional, Bargnoux, A.-S., additional, Dupuy, A.-M., additional, Cristol, J.-P., additional, Hammer, F., additional, Scherberich, J. E., additional, Pizzarelli, F., additional, Ferro, G., additional, Amidone, M., additional, Dattolo, P., additional, Gauly, A., additional, Golla, P., additional, Clajus, C., additional, Beutel, G., additional, Haller, H., additional, Schmidt, B. M. W., additional, Kielstein, J., additional, Nakazawa, R., additional, Shimizu, Y., additional, Uemura, Y., additional, Kashiwabara, H., additional, Watanabe, D., additional, Kato, T., additional, Fuse, M., additional, Azuma, N., additional, Nakanishi, N., additional, Kabayama, S., additional, Alquist Hegbrant, M., additional, Bosch, J. P., additional, Righetti, M., additional, Ferrario, G., additional, Serbelloni, P., additional, Milani, S., additional, Lisi, L., additional, Tommasi, A., additional, Mambelli, E., additional, Bolasco, P. G., additional, Scotto, P., additional, Savoldi, S., additional, Serra, A., additional, Corazza, L., additional, Tomisawa, N., additional, Jinbo, Y., additional, Kobayashi, Y., additional, Kawakubo, Y., additional, and Sakurasawa, T., additional

Published
2011
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48. Increased peritoneal permeability is associated with decreased fluid and small-solute removal and higher mortality in CAPD patients.

Author

Wang, T, Heimbüger, O, Waniewski, J, Bergström, J, and Lindholm, B

Abstract

Background: Recent studies suggest that increased peritoneal membrane permeability is associated with higher morbidity and mortality in peritoneal dialysis patients. It is not known, however, whether the difference in clinical outcome among different peritoneal transport groups is due to differences in peritoneal fluid and solute removal. In the present study, we compared the peritoneal fluid and solute transport and clinical outcome in CAPD patients with high (H), high-average (H-A), low-average (L-A) and low (L) peritoneal transport patterns. [ABSTRACT FROM PUBLISHER]

Published
1998
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49. Evaluation of an experimental rat model for peritoneal dialysis: fluid and solute transport characteristics.

Author

Park, M. S., Heimbürger, O., Bergström, J., Waniewski, J., Werynski, A., and Lindholm, B.

Abstract

The aim of this study was to develop a reference model of fluid and solute transport during experimental peritoneal dialysis in rats, which would simulate the conditions of clinical dialysis in CAPD patients as much as possible. For this purpose a 4-h dialysis study was performed in 13 normal Sprague-Dawley rats with conventional glucose solutions (Dianeal 1.36% solution, n=6 and Dianeal 3.86% solution, n=7) and a protocol and methods like those used in clinical dwell studies. The dilution of a marker, radioactive human serum albumin (RISA), was used to determine the intraperitoneal dialysate volume with corrections for the elimination of RISA from the peritoneal cavity and sample volumes. The isovolumetric method was employed to calculate the diffusive mass transport coefficients. To compare our data with reference values in CAPD patients, the data were scaled by a factor calculated as a ratio of the dialysate volume in CAPD to the dialysate volume in the rats. In a separate series of experiments the intraperitoneal hydrostatic pressure was monitored with increasing infusion volumes. The fluid transport characteristics, described as the percentage changes of the initial intraperitoneal volume, were essentially comparable to those in CAPD patients. However, the intraperitoneal volume curves were shifted more to the left than were the reported values in CAPD patients. The scaled diffusive mass transport coefficient for urea was similar to that in CAPD patients. However, the transport of other solutes, in particular glucose, was faster in the rats than in CAPD patients. The intraperitoneal hydrostatic pressure increased exponentially with increasing infusion volume relative to body weight and was 0.3–0.9 mmHg with the standard infusion volume of 30 ml in the present study. The intraperitoneal hydrostatic pressure in the rats receiving 30 mi of fluid intraperitoneally was lower than the reported intraperiCorrespondence toneal pressure in CAPD patients using 2 1 of dialysis fluid. We conclude that the present experimental model of peritoneal dialysis in the rat with a protocol and methods similar to those used in clinical studies, after appropriate scaling, seems to have fluid and solute transport characteristics that resembled those in clinical peritoneal dialysis, but considerable differences were also found. [ABSTRACT FROM PUBLISHER]

Published
1994

50. Dialysate to plasma solute concentration (D/P) versus peritoneal transport parameters in CAPD.

Author

Heimbürger, O., Waniewski, J., Werynski, A., Park, M. Sun, and Lindholm, B.

Abstract

The relationship between dialysate to plasma solute equilibration ratio (D/P) and diffusive (diffusive mass transport coefficients, K) as well as convective (sieving coefficient, S, and net ultrafiltration) transport characteristics were studied in clinically stable CAPD patients and in patients with loss of ultrafiltration capacity (UFC). Forty-one 6-h single-dwell studies with standard glucose-based dialysis fluids containing 1.36/ ( = 9), 2.27% ( = 9), and 3.86% ( = 23) anhydrous glucose were carried out in 33 clinically stable CAPD patients. Eleven patients with loss of UFC were studied with 3.86% glucose solution. Intraperitoneal dialysate volumes were calculated from the dilution of the tracer (I-albumin) with a correction applied for its elimination from the peritoneal cavity. K and S were estimated using the Pyle-Popovich-Moncrief model with aqueous plasma concentrations. A theoretical D/P curve was derived with and without taking convective transport and peritoneal reabsorption into account. The three different glucose solutions yielded D/P curves which were similar for urea and potassium. For creatinine a slower equilibration and for glucose and sodium a faster decrease in dialysate concentration were observed with more hypertonic solutions. In general, there was a strong correlation which was best at 240 min between D/P (for glucose dialysate/initial dialysate concentration, D/D) and K for all solutes (except sodium), whereas the correlation between D/P and convective transport parameters was much weaker. K for creatinine (with 3.86% glucose solution) could be estimated (=0.98) from aqueous D/P using the experimental formula: creatinine K= −1.8−In (1−D/P)/0.1. Patients with loss of UFC due to increased diffusive transport ( = 8) could be discriminated from the clinically stable patients using K and D/P (or D/Do) for creatinine and glucose or D/P for sodium. However, patients with loss of UFC associated with increased peritoneal reabsorption ( = 2) could not be identified using these parameters. Theoretically derived D/P curves were in excellent agreement with measured D/P for 1.36% glucose solution and simulations were satisfactory also for the 2.27% and 3.86% solutions provided that the effect of convective transport was taken into account. The standardized peritoneal equilibration test (PET) as proposed by Twardowski . [17] seems to be appropriately designed as regards duration of the dwell and the choice of glucose and creatinine as investigated solutes. Thus, PET can be recommended as a sensitive routine investigation for the monitoring of normal/abnormal peritoneal transport behaviour in peritoneal dialysis patients. [ABSTRACT FROM PUBLISHER]

Published
1994

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