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Objective To apply cone beam CT measurements(CBCT)to analyze the effect of skeletal Class Ⅲ high angle with deviation on upper airway morphology and hyoid position. Methods A total of 120 patients with skeletal Class Ⅲ high angle malocclusion who visited our hospital from September 2019 to December 2022 were selected. CBCT was taken in all subjects. According to the degree of mandibular deviation (MD) of the point under the chin from the median sagittal plane, the 120 patients were divided into three groups: non-migratory, mildly migratory, and severely migratory groups, and the volume of the upper airway as well as the position of the hyoid bone of three groups were measured and analyzed respectively. Results There was no significant difference in the volume and minimum cross-sectional area of the nasopharyngeal segment, palatopharyngeal segment, and minimum cross-sectional area of the laryngopharyngeal segment. No siginificant difference was found between the position of the hyoid bone(HB) on the Y-axis (Y-HB) and the position of the hyoid bone on the Z-axis(Z-HB) among the three groups(P>0.05). Compared with the other two groups, the volume and total volume of the nasopharyngeal segment, the laryngopharyngeal segment, and minimum cross-sectional area of the laryngopharyngeal segment in the group of severe deviation were significantly reduced(P

Objective To cultivate and breed laboratory cats in conventional laboratory animal facilities, collect background data on laboratory cats, and compare them with purchased domestic cats to assess the feasibility of breeding laboratory cats. Methods Indigenous cat breeds were introduced for reproduction and population expansion under conventional laboratory environment, with recording of kitten survival rates and growth curves. Indicators of 20 laboratory cats of F1 generation (half male and half female), including complete blood count, blood biochemistry, organ mass, organ coefficient, heart rate, and blood pressure, were detected and comparisons between sexes were made. Blood pressure values and sensitivity to histamine of these cats were measured using depressor substance detection method in the Pharmacopoeia of the People's Republic of China-Four Parts: 2020, and were compared with the data from 173 concurrently purchased domestic cats. Results Laboratory cats adapted well to the environment of conventional laboratory facilities, with a survival rate of 77.08% of kittens at 8 weeks of age. Red blood cell count, hemoglobin content, mean corpuscular hemoglobin concentration, and hematocrit in male laboratory cats were significantly higher than those in females (P0.05). Compared to laboratory cats, purchased domestic cats had significantly higher heart rate, systolic pressure, and mean blood pressure (P

[Objective] This study was aimed to estimate the amount of water conservation in Shaanxi Province. [Methods] The InVEST model and PLUS model were coupled to calculate the water conservation amount in Shaanxi Province from 2000 to 2020 and predict the water conservation amount under land use changes in the future in 2030. [Results] The average water conservation amount in Shaanxi Province from 2000 to 2020 was 132.25 mm, with a spatial distribution characteristic of gradually increasing water conservation from north to south. From the perspective of vegetation types, forest land was the main body of water conservation in Shaanxi Province. The average annual water conservation amount was 199.55×108 m3. From the administrative region, Ankang City had the largest water conservation amount(308.96 mm). The total amount of water source conservation in 2030 will be 285.16×108 m3 and 8.68×108 m3 less than that in 2020. [Conclusion] The water conservation amount of Shaanxi Province will show a slight downward trend from 2020 to 2030 in the future.

With the sustained growth of economy and significant changes in social demographics, the issue of elderly-related diseases has increasingly drawn attention particularly. Alzheimer's disease (AD),as a representative disease of neurodegenerative diseases has become a major challenge, affecting the health and quality of life among the elderly population severely. In recent years, the incidence, prevalence, and mortality rate of AD increase in China, imposing substantial economic burdens on families, society, and the entire healthcare system. To proactively address this challenge and respond to the national 'Healthy China Action' initiative, leading experts from Renji Hospital, Shanghai Jiao Tong University School of Medicine,and Chinese Center for Disease Control and Prevention Chronic Non-communicable Disease Control Center, Fudan University School of Public Health, Shanghai Mental Health Center, Ruijin Hospital,Shanghai Jiao Tong University School of Medicine, Fujian Medical University, and other authoritative institutions, have jointly authored the 'China Alzheimer Disease Report 2024'. Building upon previous editions of 2021, 2022, and 2023, this report updates epidemiological data on AD in China, thoroughly analyzes the latest economic burdens of the disease, and comprehensively evaluates the current status of AD diagnosis and treatment services, as well as the allocation of public health resources in our country. The release of the 'China Alzheimer Disease Report 2024' not only reflects China's progress and efforts in AD research and prevention, but also underscores the social heightened concern for elderly health issues. It aims to provide scientific and technical guidance and robust data support for the prevention, diagnosis, and treatment of AD, offering a professional basis for the government and relevant departments to formulate targeted health policies and intervention measures. Furthermore, it serves as a platform for promoting academic exchanges and cooperation in this field domestically and internationally. Through the dissemination and application of this report, we anticipate it will not only serve as a reference for professionals but also enhance public awareness of AD, promote active participation across various sectors of society, and jointly advance the development of elderly health care in China, empowering us towards achieving 'healthy aging'.

A high-fidelity computational fluid dynamics and rigid-body dynamics coupling platform suitable for virtual flight simulation of dual-spin projectile is developed. Based on this platform, the influence of rotating canards on the trajectory following stability of the dual-spin projectile is studied. To accurately characterize the differential rotation effect of the dual-spin projectile’s fore and aft bodies, a slidingmesh algorithm is introduced into the in-house unstructured mixed grid flow field numerical simulation program HUND3D. By conducting axisymmetric rotational unsteady simulations of the dual-spin projectile and investigating the flow characteristics and aerodynamic properties under different canard rotation speeds, the dynamics mechanism of the trajectory following process is analyzed. Through the coupled solution of unsteady Reynolds-averaged Navier-Stokes equations and seven-degree-of-freedom rigid-body dynamics equations, virtual flight simulations of the dual-spin projectile with different curvature trajectories are realized. The dynamic mechanism of the trajectory tracking process is analyzed, and strategies for improving trajectory following stability by controlling the canard rotation speed based on the analysis of aerodynamic characteristics are studied. The research results indicate that the aerodynamic disturbances generated by canard rotation can significantly affect the lateral force and yawing moment of the projectile. By controlling the rotation speed of the fore canards to produce a yawing moment favorable for trajectory tracking, the trajectory following stability can be improved to a certain extent.

This study targets at asymmetric deformation of narrow coal pillar in gob-side entry driving.We put forward the bidirectional reinforcement of narrow pillar with opposite-crossing anchor cable.Specifically, we designed two types of anchor cable structure: the byelongation type and the expansion lock type, and carried out the pull-out test of opposite-crossing anchor cable, the test shows that both anchor cable structures could meet the tensile requirements.We conducted comparative analysis on the morphology of anchor cable failure, construction convenience and the economic aspect of material selection, where the expansion lock type crossed anchor was selected for narrow coal pillar bidirectional reinforcement.Furthermore, we investigated the bearing deformation patterns of coal pillars and the stress characteristics of anchor cables under different reinforcement methods through similar model tests and numerical simulation.Results show a 96.04% increase of peak load in the specimen reinforced by the double-row tight opposite-crossing anchor cable compared with that of the not reinforced specimen, and higher stability of the narrow pillar reinforced by the double-row tight opposite-crossing anchor cable as the rows of the anchor cable increases in number.The expansion lock anchor type crossed cable improved the energy storage and the critical failure point before the coal pillar was destroyed.Finally, the engineering test of expansive lock type crossed anchor cable to reinforcing narrow coal pillar was carried out in the transportation roadway of 123 lower 04 working face of Jining No.3 Coal Mine.The monitoring show that the anchoring force of the anchor cable exceeded 220kN, with 70& reduction of the coal pillar in the reinforcement area and good overall stability of the narrow coal pillar.It proves the feasibility of the bidirectional reinforcement technology of narrow pillar and provides new technical way for gob-side entry driving.

Several anti‑Aβ monoclonal antibody drugs have been approved for clinical use at home and abroad recently. In order to facilitate its safe and effective treatment of anti‑Aβ monoclonal antibody drugs for Alzheimer's disease (AD) in China, we present recommendations for the clinical use of anti‑Aβ monoclonal antibody drugs based on existing clinical trials and the clinical practice of AD treatment with Aducanumab at Ruijin Hospital Hainan Branch, Shanghai Jiaotong University School of Medicine. The recommendations include clinical indications, pre ‑ medication assessment and preparation, medication instructions and precautions, as well as post ‑ medication clinical monitoring, which is aimed to furnish clinicians with comprehensive medication guidance.

Abstract [Objective] To explore the response and adaptation of leaf functional traits of Atractylodes chinensis to Horqin sandy land. [Methods] Semi-wild A . chinensis. seeds from four seed sources were transplanted to the Chinese (Mongolian) medicinal herb research base in Naiman Banner through a homogeneous gardening experiment. The leaves of three-year-old A . chinensis were used as materials, to examine how A . chinensis's leaf structure and functional properties responded to and adapted to the sandy land of Horqin. [Results] The degree of leaf cleavage in the lower portion of the A . chinensis introduced from Zhalute Banner was evident. Additionally, the thickness of the upper and lower epidermal cells of the leaves of the A . chinensis introduced from Weichang County and Zhalute Banner were found to have significantly higher coefficients of variation and plasticity indices than those of the other seed source sites; additionally, their palisade/spongy ratios and the tightness of their tissues and structures were greater. The top layer of A . chinensis leaves from Arong Banner and Zhalute Banner sources had a greater number of stomata, whereas the upper layer of A . chinensis leaves from Harqin Banner had less stomata and a low stomatal density. A . chinensis leaves from the Zhalute Banner and Weichang County sources had a robust photosynthetic capacity, and the leaves from the Harqin Banner sources had a notably greater number of stomata in the lower epidermis than the leaves from the other three sources. [Conclusion] The results show that A . chinensis from Weichang County and Zhalute Banner are highly adaptable to the Horqin Sandy land.

Functional movement disorder (FMD) is a common type of conversion/dissociative disorder. In recent years, the continuous development of imaging techniques such as fMRI, DTI and PET, as well as analytical methods such as morphological analysis and fiber tract tracking, not only provides technical support for the study of neurobiological mechanisms of FMD, but also has important value for its differential diagnosis, efficacy evaluation and prognosis prediction. This article reviews the progress of imaging research on FMD, so as to provide basis for diagnosis, treatment and pathophysiological mechanism of the disease.

Functional movement disorder (FMD) is a common subtype of functional neurological disorder (FND). Currently, multi⁃disciplinary team (MDT) is recommended for FMD. In addition to drug and psychological treatment, rehabilitation treatment is also of great value. Rehabilitation treatment improve the motor control function of patients through the comprehensive application of physical therapy, non ⁃ invasive nerve stimulation therapy and occupational therapy, enhance the activities of daily living (ADL). This article reviews the progress of rehabilitation treatment for FMD, so as to provide theoretical basis for accurate rehabilitation treatment for FMD.

Objective To explore changes of brain structure in patients with functional movement disorder (FMD) and their correlation with disease severity. Methods Nine patients with FMD (FMD group) as well as 10 gender⁃ and age⁃matched healthy volunteers (control group) were recruited in Ruijin Hospital, Shanghai Jiaotong University School of Medicine, from May to October 2023, and then they underwent MRI. Simplified Functional Movement Disorder Rating Scale (S ⁃FMDRS) was used to assess movement disorder symptoms and severity. Clinical Global Impression ⁃ Severity (CGI ⁃ S) was used to evaluate disease severity. Somatoform Dissociation Questionnaire ⁃ 20 (SDQ ⁃20) was used to assess body dissociation. Chinese version of Maltreatment and Abuse Chronology of Exposure (MACE) was used to assess childhood abuse situation. 36⁃Item Short Form of Health Survey (SF⁃36) was used to assess health status. Hamilton Anxiety Rating Scale (HAMA) and Hamilton Depression Rating Scale 17 (HAMD⁃17) were used to evaluate anxiety and depression. Results Compared with the control group, the FMD group exhibited higher scores on SDQ⁃20 (Z = 2.259, P = 0.028) and Chinese version of MACE (t = ⁃ 3.570, P = 0.002) as well as HAMA (t = ⁃ 3.999, P = 0.001), while SF⁃36 scores for vitality (t = 3.091, P = 0.009) and social functioning (t = 2.275, P = 0.046) were lower in the FMD group. Cortical thickness was greater in the FMD group in the right inferior occipital gyrus and sulcus cortex (t = ⁃ 2.924, P = 0.009), right anterior cingulate gyrus and sulcus cortex (t = ⁃ 3.286, P = 0.004), right orbitofrontal cortex (t = ⁃ 2.381, P = 0.029), while thickness in the left subcallosal area (t = 2.492, P = 0.023) and left paracentral lobule gyrus and sulcus (t = 2.139, P = 0.047), as well as volume of the right cerebellar white matter (t = 2.685, P = 0.016), left cerebellar white matter (t = 2.121, P = 0.049), and the middle posterior region of the corpus callosum (t = 2.550, P = 0.021) were smaller than those of the control group. Correlation analysis revealed left cerebellar white matter were positively correlated with disease duration (r = 0.837, P = 0.038), while cortical thickness in the left subcallosal area were negatively correlated with disease duration (r = ⁃ 0.831, P = 0.040). Conclusions There are structural changes in the limbic system, sensorimotor area, visual cortex, and certain white matter regions in the brains of FMD patients, and several regions were correlated with the disease duration.

Functional neurological disorder (FND) is a kind of voluntary motor or sensory system disease with definite symptoms. As a kind of nervous system disease which can be included in chronic disease management but not easy to identify, its increasing number of patients and social burden have aroused great attention in society. Based on the author′s clinical practice and thinking on FND in recent years, this paper analyzes how to further strengthen the diagnosis, treatment and management of FND in China, and puts forward relevant countermeasures and suggestions, so as to achieve early detection, early diagnosis and early treatment of diseases, and improve the quality of life of patients.

Objective To preliminarily summarize the epidemiological and clinical characteristics of functional movement disorder (FMD) based on movement disorders clinic in China. Methods and Results A total of 593 patients with movement disorders newly diagnosed in movement disorders clinic of 22 clinical medical centers from August to September in 2023 were included, including 37 patients (6.24%) with FMD and 556 patients (93.76%) with organic movement disorder. Comparison of the epidemiological characteristics of the 2 groups, the proportions of corona virus disease (COVID⁃19) infection (χ2 = 4.217, P = 0.040) and psychopsychological symptoms (χ2 = 18.694, P = 0.000) in the FMD group were higher than those in the organic movement disorder group, while age (t = 3.757, P = 0.000), age of onset (t = 3.720, P = 0.000) and proportion of hypertension (χ2 = 4.736, P = 0.030) were lower than those in the organic movement disorder group. Comparison of the clinical characteristics of the 2 groups, the FMD group had higher proportions of tremor (χ2 = 3.955, P = 0.047) and myoclonus (Fisher′s exact probability: P = 0.011) than the organic movement disorder group, and the proportions of parkinsonism (χ2 = 8.491, P = 0.004) and gait disorder (χ2 = 5.028, P = 0.025) were lower than those in the organic movement disorder group. Conclusions The age and age of onset, as well as the proportions of COVID⁃19 infection, hypertension, psychopsychological symptoms, tremor, myoclonus, parkinsonism and gait disorder with FMD were different from those with organic movement disorder in China.

Functional movement disorder (FMD) is a common functional neurological disorder (FND), which is mainly manifested as subjective dyskinesia and cannot be explained by existing diseases. Although there was no record of the corresponding disease name in ancient Chinese medicine, the disease caused by mental and psychological factors has been long recognized, and a large number of documents have been left to record the diagnosis and treatment process of such diseases. In this paper, three typical ancient medical cases related to FMD were reviewed, and the traditional Chinese medicine diagnosis and treatment ideas and modern medicine recognition of these diseases were systematically sorted out, so as to broaden the clinical treatment ideas of the disease.

Functional myoclonus is a group of paroxysmal abnormal movements, which is one of the common types of functional movement disorder (FMD). The clinical characteristics include sudden occurrence and sudden arrest, inconsistent symptoms, distraction, entrainment, and placebo or suggestion therapy is effective. Long burst duration, variable muscle recruitment pattern and relatively characteristic bereitschafts potential (BP) can be seen in neuroelectrophysiological examination. The diagnosis is mainly based on the positive clinical symptoms and electrophysiological examination results. At present, there is no unified guideline for treatment, which recommends psychotherapy, physical therapy and multidisciplinary cooperation. This article reviews the clinical characteristics, diagnosis and differential diagnosis, treatment and prognosis of functional myoclonus, in order to help clinical early accurate diagnosis, timely treatment, and improve patient prognosis.

Functional limb weakness is a common functional motor disorder, and its clinical diagnosis is mainly based on the medical history, neurological examinations and patients' positive signs. It is prone to misdiagnosis in the clinical practice, treatment requires diagnostic interpretation, physical therapy, and psychological therapy in a multi⁃disciplinary team pattern. This article reviews the progress in clinical manifestations, diagnosis, differential diagnosis, and the treatment of functional limb weakness, to help clinicians diagnose and treat functional limb weakness effectively in clinical practice, improving patients' prognosis.

Objective To explore the predictive validity of joint function screening for military training injuries in new recruits. Methods A total of 113 new recruits were subjected from a training institution of the Joint Logistic Support Force of PLA from March to May 2022. Their joint function was evaluated, and the military training injuries were recorded during the training. Jarque-Brea (JB) normality test, binary logistic regression, receiver operating characteristic (ROC) curve and OR value calculation were used to comprehensively evaluate the validity of joint function screening in predicting military training injuries. Results The average score of joint function was 9.46 in the participants, and statistical difference was observed in the score between the injured recruits and uninjured recruits (7.30±1.45 vs 9.92±1.74, P < 0.01). Binary logistic regression analysis showed that the screening score of joint function was an important influencing factor of military training injuries (β=-1.098, P < 0.01). ROC curve analysis showed that the AUC value was 0.875 (95%CI: 0.789~0.952 P < 0.01) in the prediction of training injuries, with a sensitivity of 75% and a specificity of 80.6%, and the injury risk threshold was 8.5 points. The potential injury risk probability in the new recruits with < 8.5 points in screening was 12.5 times higher than those with the score ≥8.5 points (OR=12.5). Conclusion The screening score of joint function has good correlation with military training injury, and shows good predictive performance for the injuries. Therefore, it can be used as a prediction tool of military training injuries for new recruits in all branches of the military.

The aim of this study was to explore the changes in pH and pepsin concentrations in oral lavage fluid of rabbit reflux model. A total of 18 New Zealand rabbits were randomly divided into two groups. The lower esophageal sphincters (LESs) of the rabbits in the experimental group (EG) were dilated by balloon after the LESs were localized by manometry. The pH levels of the throat and the lower esophagus were monitored 1 week before and 2 weeks after inflation. Oral lavage fluid was collected 1 week before, and 2 and 8 weeks after inflation. The pH monitoring showed that the percentage of reflux time, the number of reflux events, and the longest time of reflux after the dilation (AE) in the EG were significantly higher than before the dilation (P < 0.01). The pepsin concentrations at 2 and 8 weeks AE in the EG were significantly higher than that before and that in the control group (P < 0.05). Based on receiver operating characteristic curve analysis, the best diagnostic threshold value was 30.3 ng/ml. The reflux model constructed by balloon inflation of the LES in rabbits is characterized by a decrease in throat pH and an increase in salivary pepsin concentration.

With the current-assisted bonding technology, the rapid brazing of SiC ceramics was realized at 1125℃ with CoFeCrNiCuTi2 high-entropy alloy as the bonding layer material, which improves the bonding efficiency and ensures the full diffusion of elements. The influence of brazing temperature on the microstructure and mechanical properties of the bonding interface was studied. The results show that the obtained brazed joint has no obvious defects and the weld microstructure is mainly composed of high-entropy FCC, TiC phase and Cr23C6 phase. The formation of TiC reaction layer with dense interface inhibits the decomposition of high-entropy alloy and the formation of intermetallic compounds to a certain extent, and relieves the thermal stress between interface matrix SiC and high-entropy alloy filler. At the same time, due to the delayed diffusion effect of high-entropy alloy filler, the filler in the center of weld still keeps the FCC structure of high-entropy alloy. The mechanical test shows that the strength of brazed joint decreases at first and then increases. When the joining temperature is 1125℃, the maximum bending strength of SiC joint is 37 MPa, which is higher than that of ordinary Ni-based filler by about 21.3 MPa.

BackgroundBeing complex and highly heterogeneous with regard to the etiology and clinical manifestations of depression， neuroimaging studies make a breakthrough for exploring the biological subtypes of depression， while the current data-driven approach for the identification of subtyping depression using structural magnetic resonance imaging （MRI） data is insufficient.ObjectiveTo explore the biological subtypes of depression using diffusion tensor imaging （DTI） and machine learning methods.MethodsA total of 127 patients with depression who attended Beijing Anding Hospital from September 2017 to August 2021 and met the Diagnostic and Statistical Manual of Mental Disorders， fourth edition （DSM-IV） diagnostic criteria were included， and another 80 healthy individuals matched for gender and age were recruited through advertisements in surrounding communities during the same period. DTI findings， demographic characteristics and clinical data were collected from all participants. Tract-based spatial statistics （TBSS） and the Johns Hopkins University （JHU） white matter probability maps were used to extract fractional anisotropy （FA） values of white matter tracts. A semi-supervised machine learning technique was used to identify the subtypes， and the FA values for whole brain white matter of patients and controls were compared.ResultsPatients with depression were classified into two biological subtypes. FA values in multiple tracts including corpus callosum and corona radiata of subtype I patients were smaller than those of healthy controls （P0.05）， while subtype I patients scored lower on HAMD-17 than subtype II patients after 12 weeks of treatment （t=2.410， P

Objective To screen the mutations of the deafness-related genes in explosion-induced hearing loss (EIHL) based on whole exome sequencing (WES). Methods A cross-sectional study was conducted on a total of 105 workers who accepted long-term exposure of impulse noise. Noise testing was conducted in their working environment and pure tone audiometry was conducted on the workers. Whole exome sequencing was performed on workers with EIHL based on their audiometric results. The WES results were analyzed by bioinformatics to screen for mutations in genes related to deafness in workers with EIHL. Results There were 75 workers with EIHL. The pure tone audiometry results showed, compared with the workers with normal hearing, the workers with EIHL displayed a worse performance in different frequencies (P < 0.05). Through screening of WES, the rare and detrimental missense mutations happened in 29 deafness-related genes among the workers with EIHL, including 37 harmful missense mutation sites. GJB4 had the highest frequency in mutation, which occurs in 4 workers, with mutation sites of C292T, C370T, and G376A. Conclusion GJB4 is the deafness-related gene with the highest mutation frequency in the workers with EIHL.

Functional parkinsonism (FP) is a disorder caused by psychological factors rather than neurodegeneration. Functional parkinsonism has a great influence on patients' quality of life and daily function. However, due to overlapping with some of the symptoms of Parkinson's disease (PD), the diagnosis of functional parkinsonism is often delayed or omitted. Early identification and diagnosis of functional parkinsonism is challenging and crucial to the treatment and prognosis of patients. This review summarizes the importance of clinical positive signs and auxiliary examinations in the diagnosis and differential diagnosis of functional parkinsonism. The differences of clinical features between functional parkinsonism and PD were compared in detail. This review aims to improve clinicians' diagnosis, differential diagnosis and treatment capabilities of functional parkinsonism.

Polyborosiloxane（PBS） is a supramolecular material， the material itself has a physical cross-linked network structure, and has the characteristics of high and low temperature resistance, weather resistance, electrical insulation and self-healing. However, the mechanical properties of polyborosiloxane material prepared by existing methods are poor, which limits its application in some fields. In order to improve the mechanical properties of polyborosiloxane and broaden the application field of the material, in this paper, a vinyl-containing polyborosiloxane was prepared by reacting high-molecular-weight polymethylvinylsiloxane（VMQ）with boric acid（BA）at high temperature. The polyborosiloxane composite material with surface self-adhesiveness was obtained by introducing vinyl structure and fumed white carbon black and undergoing thermal vulcanization treatment. The structure, dynamic mechanical properties, thermal stability, mechanical properties and self-adhesive properties of polyborosiloxane composite were measured, and the formation of B—O—Si structure was confirmed by infrared reflection spectroscopy. The results show that the B∶O dynamic bond is formed inside the polyborosiloxane composite material, and the surface of the material has certain self-adhesive properties. The peel strength formed by self-adhesion can reach 4 N/cm, the tensile strength is 4.154 MPa, and 5 % thermal mass loss temperature is 394.8 °C, which means that the sample has good mechanical properties and thermal stability.

In the late 1990s, the landscape of the Korean film industry underwent a major change as Korean films emerged strongly and swept through Asia and the world with their consumer culture. With the advent of the Internet+ era in the new century, the consumer culture of Korean cinema has changed dramatically. In order to study the impact of the Internet+ era on Korean film consumption culture clearly, this paper analyzes the change in Korean film genres with the Internet trend and the distribution of the Korean film industry in the Internet+ era through Internet information dissemination model and personalized recommendation algorithm. From 2012 to 2021, the main genres of Korean movies changed from romance, drama, and war movies to crime, action, and disaster movies. Among them, the average share of war films reached 11.20%. The average share of disaster films reached 11.11%. The average share of action films is 10.88%. The average share of drama films was 10.97%. In terms of the film industry, the market share of local Korean films has always been able to keep from being surpassed by imported films after surpassing them. 2013 saw the largest gap between imported and local films, with a difference of 19.4 percentage points. In the Internet+ era, audience psychology, consumer demand, and business models have had a profound impact on the consumer culture of Korean films, not only changing the traditional layout of the Korean film market but also allowing film creators to consciously or unconsciously introduce new consumer culture themes in line with the Internet public.

Fuzzy sets and deep learning models have accurate recognition accuracy in automatic detection. To be able to accurately identify tobacco debris and improve the quality of cigarettes, this paper proposes the design of a tobacco debris detection system with a deep learning model and fuzzy quadratic theory. The collected data is stored to AL422B by quadratic fuzzy set timing conversion, the cached image data is read by the microcontroller, the image pixel points are output, and the external controller and internal registers are set to read the tobacco image. The integrated Thumb extended instruction set to obtain the CPU clock frequency makes the controller interrupt and ensures PWM output. Integrate the internal fixed oscillator and external integrated control circuit to debug the program interface circuit to prevent power on and off misoperation. The negative log-likelihood function is obtained by following the activation rules given by the visible layer and hidden layer activation functions. The RBM is trained by quadratic fuzzy set estimation to optimize the parameters; test sample sets appear overfitting, combined with DBN pre-training and fine-tuning, iterative output, and labeling target data to meet the preset requirements to achieve intelligent detection of tobacco debris. The result analysis shows that the deep learning model and the quadratic fuzzy set generalization ability and accuracy are high, the highest F-value in tobacco clutter detection reaches 100%, and the system is designed to detect tobacco clutter automatically with high accuracy and good detection of clutter.

This paper explores the principle of deep reinforcement learning algorithm application and constructs the digital teaching model of Civics through the recurrent neural network, Markov decision process, Actor-Critic algorithm and collaborative filtering recommendation algorithm. On this basis, the state representation model and decision-making model are invoked to improve the diversity optimization recommendation of the deep reinforcement learning algorithm. Aiming at the problems existing in the practical application of the OBE concept, the model constructed in this paper is utilized to propose a multi-platform integration of the Civics digital learning model. The objective of empirical and simulation experiments is to confirm the model’s implementation and recommendation effects, respectively. In the validation of hyperparameter d and N values, the DQN model achieves the optimal recommendation effect when the d values are 65 and 63 on the HetRec and MovieTweetings datasets. During the implementation of the digital teaching evaluation of the course Civics, more than 60% of the students rated the teacher’s feedback session higher. Overall, the 6 dimensions were rated higher, and the number of students who chose to be fully compliant and conforming was more than 200.

Background Diabetic foot ulcer (DFU) is a serious diabetic complication with a high recurrence rate after healing. There is a lack of systematic evidence-based studies on multiple risk factors associated with its recurrence. Objective To investigate the risk factors for DFU recurrence after healing, providing evidence to inform the prevention and treatment of DFU. Methods A case-control study design was used. Patients with an initial inpatient diagnosis of DFU were selected from Hospital of Chengdu University of TCM from January 1, 2016 to February 1, 2019 as the source population, among whom those with and without a recurrence within three years after healing were assigned to case and control groups, respectively. Baseline characteristics, information related to diabetes and DFU were collected from both groups. Risk factors for DFU recurrence were screened by unconditional multivariate Logistic regression analysis. The relationships of DFU recurrence with the number of risk factors and the time to recurrence were further analyzed. Results Among the source population (n=256), 210 had healed DFU, and 190 of them were included for final analysis after excluding 12 missing cases and 8 with incomplete information. The overall recurrence rate within three years after DFU healing was 45.3% (86/190). Multivariate Logistic regression analysis showed that age >60 years〔OR=3.270, 95%CI (1.335, 8.005), P=0.010〕, HbA1c >7.5%〔OR=2.691, 95%CI (1.242, 7.687), P=0.045〕, peripheral arterial disease (PAD) 〔OR=2.241, 95%CI (1.185, 5.101), P=0.044〕, osteomyelitis〔OR=3.256, 95%CI (1.369, 7.744), P=0.008〕, callus〔OR=2.068, 95%CI (1.262, 4.446), P=0.043〕, ankle-brachial index (ABI) 60 years, HbA1c >7.5%, PAD, osteomyelitis, callus, ABI

Psychogenic nonepileptic seizure (PNES) is a common functional neurological disorder with complex neuropsychiatric etiology and clinical characteristics. Its diagnosis is mainly based on medical history and symptomatology, which is easily to misdiagnosis in clinical practice. Pay attention to distinguish it from epilepsy, and reduce or completely eliminate seizures. This review introduces the latest advances from four aspects: clinical manifestations, diagnosis, differential diagnosis, and treatment of PNES, to help clinicians diagnose and treat PNES effectively in clinical practice, improving patients' life quality.

Direct-drive wind farms (DDWF) merged into weak AC systems have the risk of sub-synchronous oscillations (SSO). Because the DDWF model has a higher order, it needs to be reduced for actual analysis. When analyzing the SSO problems, the existing balanced reduction method cannot accurately keep SSO modes of the system during the reduction process. To solve this problem, a balanced reduction method for SSO analysis is proposed. This method is based on the participation factor analysis and retains the state variables which strongly related to the SSO model. Combining with the Hankel singular value to determine the reduction order, a reduced-order system model consistent with the SSO characteristics and dynamic characteristics of the full-order system model is established. Firstly, a balanced system model by balancing the small signal model of the full-order system is established. Then, the participation factor analysis is performed on the balanced system model, combined with the Hankel singular value to ensure the set of retained state variables, and the residual order reduction method is used to establish the reduced-order system model. Finally, by comparing the full-order system model and the reduced-order system model, the results show that the proposed reduced-order method is suitable for the study of DDWF integration into weak AC system SSO.

Due to the fluctuation of PV power, it is difficult to keep the active power of the PV grid-connected inverter constant. To address the above problems, this paper proposed a new three-level integrated photovoltaic storage machine consisting of a T-type three-level DC/AC converter, a three-level Boost converter and a three-level bi-directional DC/DC converter and related control strategies. The three-level structure allowed for lower switching losses resulting in higher system efficiency and wider voltage range adaptability. In terms of control, frequency differentiation and deviation control were introduced in the control of the energy storage DC/DC converter to achieve frequency regulation of the transient/static support of the active power of the parallel network. The simulation and experiment show that when the frequency fluctuation range is 50.02~49.97 Hz (meeting the national standard), the new optical storage all-in-one machine proposed in this paper can operate stably and be easily realized.

This article reports a case of nevus trichilemmocysticus. The patient, a 48-year-old man, presented with multiple filiform keratoses and nodules. Physical examination identified multiple subcutaneous papules and nodules on the scalp, filiform keratoses on the face and bilateral ears, in addition to linear blackheads on trunk and limbs. The patient also exhibited hair loss and hypoplastic tooth. Histopathology revealed trichilemmal cyst. Nevus trichilemmocysticus is a rare organoid nevus. We reviewed literature in order to raise the awareness of the syndrome.

Aiming at the problems of high temperature and high humidity in coal mining facing, this paper studies the heat distribution law of coal mining facing, compares and analyzes the enthalpy difference method and Sigma thermal difference method to calculate the air supply volume. Based on this, mechanical cooling scheme is scientifically formulated, and the cooling effect is verified by numerical simulation method. The results show that: the air supply calculated by Sigma heat is more accurate than that by traditional enthalpy difference method, and the air supply is 22.4 kg/s, that is, 1 041.6 m3/min. It can be seen from the simulation results that the RWK350 air cooler can achieve effective cooling below the Coal Mine Safety Regulations at both the common 10 m and 15 m air duct outlet locations, thus achieving effective cooling of the driving roadway.

Functional movement disorder (FMD) is a common conversion disorder, and those who involve the face are called functional facial disorders. It seriously affects patients' social contact and work. Most clinicians have insufficient understanding of functional facial disorders, resulting in delayed diagnosis and treatment. This paper reviews the clinical features, electrophysiology, diagnosis and differential diagnosis, and treatment of functional facial disorders to improve the level of diagnosis and treatment.

Functional neurological disorder (FND) is a disorder of the autonomic motor or sensory system with well⁃defined symptoms, which covers functional movement disorder, psychogenic non⁃epileptic seizures, functional sensory disorder, functional cognitive disorder, persistent postural perceptual dizziness and so on. Its complex and diverse characteristics make the diagnosis and treatment of the disease and research difficult, so FND has long been a "gray area", but its high incidence, disability rate and high consumption of medical resources remind us that FND cannot be ignored. This paper reviews the current clinical classification of FND and the diagnostic criteria in order to improve the diagnosis and treatment by domestic colleagues.

Aiming at the problem of aggravated wear of coiled tubing caused by buckling in underground, a contact wear model between compression buckling coiled tubing and wellbore was established based on submodel method. Archard model was introduced to calculate the wear depth of coiled tubing. The removal process of material on the surface of coiled tubing was described by moving contact boundary node method to avoid mesh distortion.The wear of various compressive loads and annulus clearance are predicted.The results show that the coiled tubing is subjected to sinusoidal buckling and the wear parts are few, and the compression load and annular clearance have little influence on the wear of the coiled tubing.There are many and continuous wear parts in coiled tubing with spiral buckling, and the compression load and annulus clearance have great influence on the wear of coiled tubing This paper provides a calculation method for quantitative prediction of wear of buckling coiled tubing in wellbore.

Functional neurological disorder (FND) is a kind of autonomic motor or sensory system disease with well⁃defined clinical symptoms. It has attracted the attention of many scientists due to its high incidence and heavy social burden, and many studies have promoted the development of FND. However, due to the late start of related research in China, clinicians, patients and their families have relatively weak understanding of the concept of FND and related knowledge. This article analyzes the current status of FND diagnosis and treatment in China, proposed the suggestions to improve the level of diagnosis and treatment for FND in details and enhance related study.

Functional neurological disorder (FND) was first described by ancient Egyptians. Meanwhile, traditional Chinese medicine has long recognized this kind of disease, and it was classified into the categories of depression syndrome, hysteria, lily disease, mania, epilepsy, and so on. Throughout the understanding and research process of FND, we have experienced the iteration of terms such as "hysteria", "conversion/dissociative disorder", "psychogenic neurological disease", and "functional neurological disorder", which reflected the tight development of the cross connection between neurology and psychiatry. Since Pierre Briquet described hysteria as somatization disorder in 1859, FND have developed for nearly 150 years, representing the history of modern neuropsychology and psychology combined exploration. This article aims to systematically review the history of FND, look forward to their diagnositc and therapeutic models and prospects.

The 7075-H18 high-strength aluminum alloy sheet with a thickness of 2 mm is selected as a research object. The quench sensitivity, isothermal phase transformation and kinetics of the alloy were systematically studied via a variety of experimental and numerical techniques such as microstructural analysis, micro-hardness testing, and transformation kinetics modeling and calculation, by which the time-temperature-property(TTP) diagram was established. The results show that 7075-H18 aluminum alloy sheet possesses high quench sensitivity. The tip temperature in time-temperature-property diagram is about 350 ℃, an incubation period of only 0.23 s and a quenching sensitive temperature range of 271 ℃ to 404 ℃. In addition, the critical linear quenching cooling rate corresponding to the curve with a transformation rate of 0.5% is 969.7 ℃/s, exceeding the cooling rate achieved by cold-die quenching. During isothermal quenching, the main precipitate is the coarse η equilibrium precipitate. The longer is the isothermal time, the coarser are the η particles within the grains and at the boundaries. As a result, more particles at grain boundaries tend to be continuously distributed and precipitate free zones get wider. The phase transformation process of the 7075-H18 sheet is successfully predicted using isothermal transformation kinetics model established from the experimental data. According to the model, the precipitation rate of η particles is the highest at 350 ℃ and precipitates in way of nucleation and growth mechanisms, manifesting itself by the growth, thickening and mutual merger of lamellar precipitates. The theoretical data are consistent with the characteristics of η particles observed under transmission electron microscope and the time-temperature-property diagram.

In order to study the gas drainage effect after hydraulic fracturing, PFC2D numerical simulation is combined with COMSOL numerical simulation, and a geometric model image pixel level processing method is proposed. This method imports the PFC2D fracture geometric model after hydraulic fracturing into COMSOL software, completes the combination of two numerical simulation software, and realizes the numerical simulation of gas drainage in hydraulic fracturing coal seams. The research results show that compared with the water injection pressure of 20 MPa, the range of water injection fracturing is larger, the number of fractures is larger, the fracture expansion range is larger, and the fracturing effect is good; and under the same extraction time, the gas extraction range and drainage flow of 40 MPa water injection fracturing are large. Hydraulic fracturing can improve the gas extraction effect of coal seams, which is consistent with the actual engineering application effect.

Internal erosion is a phenomenon that fine particles migrate through the channels within coarse matrix under seepage flow. Previous studies mainly focused on the internal erosion under steady hydraulic gradient, while the studies on the behavior and mesoscopic mechanism of internal erosion under fluctuating hydraulic condition were rarely reported. In this study, a setup of transparent soil seepage test was developed. Seepage tests on two types of soils with different internal stability were conducted under steady and fluctuating hydraulic conditions respectively to investigate the internal erosion behaviors under fluctuating hydraulic condition. The macroscopic experimental phenomenon showed that when the hydraulic gradient exceeded the critical value, the hydraulic conductivity under fluctuating hydraulic condition increased faster than that under steady hydraulic condition for internally unstable soil, manifesting that hydraulic fluctuation aggravated the migration of fine particles. In order to further reveal the mesoscopic mechanism, a three-dimensional (3D) reconstruction method was employed to rebuild the mesoscopic fabric of soil based on two-dimensional cross-sectional images obtained by the planar laser scanning; and a 3D visualization digital model including coarse matrix, inter-granular pore channels and fine particles was established. By observing the distribution of fine particles in pore channels, it was found that fine particles might clog and accumulate at narrow pore throats under steady seepage. While the perturbation caused by hydraulic fluctuation could break these weak stable structures of clog and accumulation, and then restart the migration process of fine particles.

The chiral magnetic effect (CME) in high-energy heavy-ion collisions arises from the interplay between the chirality imbalance and the intense magnetic field and will cause a charge separation along the magnetic field direction. While the CME search is still ongoing in experiments, the non-CME contributions need to be excluded from the CME observables. In this work, we examine the influence of globally spin-aligned ρ mesons on the γ112 correlator, the RΨ2(ΔS) correlator, and the signed balance functions, via a toy model and a multiphase transport model (AMPT). We find that the CME observables are sensitive to the 00-component of the spin density matrix, ρ00: they receive positive (negative) contributions when ρ00 is larger (smaller) than 1/3.

In view of the fragile ecological health of the Futian mangrove wetland ecosystem, an index system for evaluating ecosystem health of the Futian mangrove wetland was established based on the ‘pressure-state-response’ (PSR) model. The ecosystem health evaluation of the Futian mangrove wetland was carried out based on three aspects: pressure subsystem, state subsystem and response subsystem. Analytical hierarchy process (AHP) was used to determine the index weight. The index system is established and evaluated by the comprehensive index method. The results showed that the ecosystem health index of the Futian mangrove wetland was 0.25262. According to ecosystem health assessment criteria, it falls into the ‘poor’ range. Based on our assessment, we consider that the structure and function of the Futian mangrove wetland ecosystem are degraded, that there has been a decline in biodiversity and that the prevailing environmental problems are serious. The results of this study can provide an effective scientific basis for the management of the Futian mangrove wetland ecosystem.

TiO2 nanostructures are synthesized in SiO2 by single implantation of Ti ions and sequential implantation of Ti and Ag ions with subsequent annealing in N2 atmosphere. The surface morphology, structure, and optical and photocatalytic properties of the fabricated TiO2 nanostructures are investigated. The experimental results indicate that the synthesized nanostructures are attributable to TiO2 in the anatase phase as annealing temperature reaches 700 ℃. However, further increase in the annealing temperature leads to the transformation of anatase TiO2 into rutile TiO2. Compared with the samples implanted only with Ti ions, the additional implantation of Ag ions promotes thermal growth of the TiO2 nanostructures and reduces their initial formation temperature and optical band gap. Moreover, results of the photocatalytic experiments demonstrate that additional Ag ion implantation improves the photocatalytic activity of the fabricated TiO2 nanostructures. The possible mechanisms for improvement in photocatalytic activity due to the presence of additional Ag ions is discussed based on measurements of photoluminescence and X-ray photoelectron spectroscopy.

To investigate the fracture mechanical behavior and failure mechanism of jointed rock mass under compression and shear load, shear tests were carried out on intact and discontinuous jointed granite. The macroscopic mechanical properties, acoustic emission signal characteristics and mesoscopic evolution law by particle flow simulation were analyzed through the experiment. A method predicting shear failure of granite was proposed by using the acoustic emission signal characteristics and its key information points. The results show that the rock integrity is damaged by the joint, and the shear modulus and peak shear strength of the rock are reduced. In addition, the existence of joints will affect the propagation path and failure mode of cracks, and the influence will be weakened with the increase of normal stress. The normal stress and joints have significant effects on the acoustic emission characteristic points. The slow growth of acoustic emission signal and the continuous decline of b value can be used as the precursor characteristics of rock shear failure. The acoustic emission signal characteristics and its key information points can be used to effectively predict the shear failure process of granite. The research results provide a reference for the shear failure mechanism analysis and stability prediction of jointed rock mass.