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In this paper, we attempt to specialize the VLM model for OWOD tasks by distilling its open-world knowledge into a language-agnostic detector. Surprisingly, we observe that the combination of a simple \textbf{knowledge distillation} approach and the automatic pseudo-labeling mechanism in OWOD can achieve better performance for unknown object detection, even with a small amount of data. Unfortunately, knowledge distillation for unknown objects severely affects the learning of detectors with conventional structures for known objects, leading to catastrophic forgetting. To alleviate these problems, we propose the \textbf{down-weight loss function} for knowledge distillation from vision-language to single vision modality. Meanwhile, we propose the \textbf{cascade decouple decoding structure} that decouples the learning of localization and recognition to reduce the impact of category interactions of known and unknown objects on the localization learning process. Ablation experiments demonstrate that both of them are effective in mitigating the impact of open-world knowledge distillation on the learning of known objects. Additionally, to alleviate the current lack of comprehensive benchmarks for evaluating the ability of the open-world detector to detect unknown objects in the open world, we propose two benchmarks, which we name "\textbf{StandardSet}$\heartsuit$" and "\textbf{IntensiveSet}$\spadesuit$" respectively, based on the complexity of their testing scenarios. Comprehensive experiments performed on OWOD, MS-COCO, and our proposed benchmarks demonstrate the effectiveness of our methods. The code and proposed dataset are available at \url{https://github.com/xiaomabufei/SKDF}., Comment: arXiv admin note: substantial text overlap with arXiv:2303.11623

Open World Object Detection (OWOD) is a novel computer vision task with a considerable challenge, bridging the gap between classic object detection (OD) benchmarks and real-world object detection. In addition to detecting and classifying seen/known objects, OWOD algorithms are expected to detect unseen/unknown objects and incrementally learn them. The natural instinct of humans to identify unknown objects in their environments mainly depends on their brains' knowledge base. It is difficult for a model to do this only by learning from the annotation of several tiny datasets. The large pre-trained grounded language-image models - VL (\ie GLIP) have rich knowledge about the open world but are limited to the text prompt. We propose leveraging the VL as the ``Brain'' of the open-world detector by simply generating unknown labels. Leveraging it is non-trivial because the unknown labels impair the model's learning of known objects. In this paper, we alleviate these problems by proposing the down-weight loss function and decoupled detection structure. Moreover, our detector leverages the ``Brain'' to learn novel objects beyond VL through our pseudo-labeling scheme., Comment: arXiv admin note: text overlap with arXiv:2301.01970

Human-Object Interaction (HOI), as an important problem in computer vision, requires locating the human-object pair and identifying the interactive relationships between them. The HOI instance has a greater span in spatial, scale, and task than the individual object instance, making its detection more susceptible to noisy backgrounds. To alleviate the disturbance of noisy backgrounds on HOI detection, it is necessary to consider the input image information to generate fine-grained anchors which are then leveraged to guide the detection of HOI instances. However, it is challenging for the following reasons. i) how to extract pivotal features from the images with complex background information is still an open question. ii) how to semantically align the extracted features and query embeddings is also a difficult issue. In this paper, a novel end-to-end transformer-based framework (FGAHOI) is proposed to alleviate the above problems. FGAHOI comprises three dedicated components namely, multi-scale sampling (MSS), hierarchical spatial-aware merging (HSAM) and task-aware merging mechanism (TAM). MSS extracts features of humans, objects and interaction areas from noisy backgrounds for HOI instances of various scales. HSAM and TAM semantically align and merge the extracted features and query embeddings in the hierarchical spatial and task perspectives in turn. In the meanwhile, a novel training strategy Stage-wise Training Strategy is designed to reduce the training pressure caused by overly complex tasks done by FGAHOI. In addition, we propose two ways to measure the difficulty of HOI detection and a novel dataset, i.e., HOI-SDC for the two challenges (Uneven Distributed Area in Human-Object Pairs and Long Distance Visual Modeling of Human-Object Pairs) of HOI instances detection.

Open-world object detection (OWOD), as a more general and challenging goal, requires the model trained from data on known objects to detect both known and unknown objects and incrementally learn to identify these unknown objects. The existing works which employ standard detection framework and fixed pseudo-labelling mechanism (PLM) have the following problems: (i) The inclusion of detecting unknown objects substantially reduces the model's ability to detect known ones. (ii) The PLM does not adequately utilize the priori knowledge of inputs. (iii) The fixed selection manner of PLM cannot guarantee that the model is trained in the right direction. We observe that humans subconsciously prefer to focus on all foreground objects and then identify each one in detail, rather than localize and identify a single object simultaneously, for alleviating the confusion. This motivates us to propose a novel solution called CAT: LoCalization and IdentificAtion Cascade Detection Transformer which decouples the detection process via the shared decoder in the cascade decoding way. In the meanwhile, we propose the self-adaptive pseudo-labelling mechanism which combines the model-driven with input-driven PLM and self-adaptively generates robust pseudo-labels for unknown objects, significantly improving the ability of CAT to retrieve unknown objects. Comprehensive experiments on two benchmark datasets, i.e., MS-COCO and PASCAL VOC, show that our model outperforms the state-of-the-art in terms of all metrics in the task of OWOD, incremental object detection (IOD) and open-set detection., Comment: CVPR 2023 camera-ready version

Vehicle re-identification (Re-ID) is urgently demanded to alleviate thepressure caused by the increasingly onerous task of urban traffic management. Multiple challenges hamper the applications of vision-based vehicle Re-ID methods: (1) The appearances of different vehicles of the same brand/model are often similar; However, (2) the appearances of the same vehicle differ significantly from different viewpoints. Previous methods mainly use manually annotated multi-attribute datasets to assist the network in getting detailed cues and in inferencing multi-view to improve the vehicle Re-ID performance. However, finely labeled vehicle datasets are usually unattainable in real application scenarios. Hence, we propose a Discriminative-Region Attention and Orthogonal-View Generation (DRA-OVG) model, which only requires identity (ID) labels to conquer the multiple challenges of vehicle Re-ID.The proposed DRA model can automatically extract the discriminative region features, which can distinguish similar vehicles. And the OVG model can generate multi-view features based on the input view features to reduce the impact of viewpoint mismatches. Finally, the distance between vehicle appearances is presented by the discriminative region features and multi-view features together. Therefore, the significance of pairwise distance measure between vehicles is enhanced in acomplete feature space. Extensive experiments substantiate the effectiveness of each proposed ingredient, and experimental results indicate that our approach achieves remarkable improvements over the state- of-the-art vehicle Re-ID methods on VehicleID and VeRi-776 datasets., Comment: 28pages,12 figures

p27$^{Kip1}$ (p27) is an intrinsically disordered protein (IDP) that folds upon binding to cyclin-dependent kinase (Cdk)$/$cyclin complexes (e.g., Cdk2$/$cyclin A), inhibiting their catalytic activity and causing cell cycle arrest. However, cell division progresses when stably Cdk2$/$cyclin A-bound p27 is phosphorylated on one or two structurally occluded tyrosine residues $[$tyrosines 88 (Y88) and 74 (Y74)$]$ and a distal threonine residue $[$threonine 187 (T187)$]$. These events trigger ubiquitination and degradation of p27, fully activating Cdk2$/$cyclin A to drive cell division. Using an integrated approach comprising structural, biochemical, biophysical and single-molecule fluorescence methods, we show that Cdk2$/$cyclin A-bound p27 samples lowly-populated conformations that dynamically anticipate the sequential steps of this signaling cascade. "Dynamic anticipation" provides access to the non-receptor tyrosine kinases, BCR-ABL and Src, which sequentially phosphorylate Y88 and Y74 and promote intra-assembly phosphorylation (of p27) on distal T187. Tyrosine phosphorylation also allosterically relieves p27-dependent inhibition of substrate binding to Cdk2$/$cyclin A, a phenomenon we term "cross-complex allostery". Even when tightly bound to Cdk2$/$cyclin A, intrinsic flexibility enables p27 to integrate and process signaling inputs, and generate outputs including altered Cdk2 activity, p27 stability, and, ultimately, cell cycle progression. Intrinsic dynamics within multi-component assemblies may be a general mechanism of signaling by regulatory IDPs, which can be subverted in human disease, as exemplified by hyper-active BCR-ABL and Src in certain cancers., Comment: 35 pages, 5 figures, supporting information 37 pages