Search

To improve the sulfur reaction kinetics and inhibit the notorious shuttle effects, a tube‐in‐tube structure decorated by carbon nanotubes (CNT) and Fe3C nanoparticles (TIT/Fe3C‐CNT) is designed as sulfur host for lithium‐sulfur batteries (LSBs) in this work. The construction of tube‐in‐tube structure increases the active sites and the specific surface area of the material. Additionally, Fe3C nanoparticles can effectively adsorb the soluble lithium polysulfides and promote their catalytic conversion, thus greatly alleviating the shuttle effects. As a result of these advantages, the TIT/Fe3C‐CNT‐based cathode exhibits a high reversible capacity of 841 mAh g−1 after 200 cycles with a low decay of 0.056 % per cycle at 0.5 C. This work provides a promising and reasonable approach to the rational design of sulfur host for LSBs. [ABSTRACT FROM AUTHOR]

Objective To analyze the research status of nursing sensitivity indicators in China, and identify possible problems, so as to provide reference for future related research. Methods bliometric analysis method was used to review the existing literature, and CNKI-CJFD, Wanfang Database and CBMdisc were used as data sources to search the related researches of nursing sensitive indicators, and analyze the publication date, region, author, fund support, journals and keywords. Results A total of 572 valid documents on nursing sensitive indicators were retrieved and published in 149 journals. The number of published documents showed an increasing trend, but the fund papers were low, the degree of interdisciplinary was poor, and the quality of documents needed to be improved. Conclusion The research on nursing sensitive indicators has gradually attracted the attention of researchers, and the research quality, breadth and depth, scientific systematicness and other aspects need to be further studied. (目的 分析我国护理敏感指标的研究现状, 明确可能存在的问题, 为今后相关研究进一步提供参考。方法 应用文献计量学分析方法回顾现有文献, 以中国期刊全文数据库、万方数据库和中国生物医学文献数据库为数据来源, 检索护理敏感指标相关研究的文献, 对文献年代、地区、作者、基金支持、期刊、关键词等方面进行分析。结果 检索获得572篇护理敏感指标有效文献, 发表在149种期刊上, 文献年发表量呈增长趋势, 但基金论文较低, 学科交叉程度欠佳、文献质量有待继续提高。结论 护理敏感指标相关研究逐渐受到研究人员的关注与重视, 在研究质量、广度与深度以及科学系统性等方面有待继续研究。)

Background: Mammalian ste20‐like kinase 4 (MST4) and autophagy have been implicated in ailments such as inflammatory and cancers. Methods: In this study, the expression of MST4 data was extracted from TCGA, GTEx, and GEPIA. The infiltration of immune cells and methylation level of MST4 in tumor and normal tissues were extracted from GEPIA 2021, TISIDB, UALCAN, EWAS, MethSurv, and MEXPRESS database. We also predict the efficacy of outcome prediction with receiver operating characteristic curve (ROC). All proteins expressions of MST4, P62, and LC3 were detected by immunohistochemistry (IHC) in paired Gastric cancer (GC) and para‐cancerous normal tissue samples. We verify the effects of MST4 on irradiation‐induced gastric death, and also investigate effects of MST4 activating autophagy in GC cell lines with various in vitro assays using western blotting. Results: We have confirmed the high transcription level of MST4 from TCGA, USLCAN, HPA, and other portals, but a rapid decrease in protein level. More, MST4 can be considered as an independent prognostic molecule, which has significant prognostic significance in tumor grade, anti‐tumor treatment, histological type, and time‐dependent ROC curve. The methylation degree of MST4 promoter region in tumor is much lower than that in normal tissue, which may be the main reason for the remarkably high transcription level of MST4. In addition, MST4 transcription level was significantly inversely proportional to the infiltration level of most immune cells. The MST4 up‐regulation and the positive association of MST4 with autophagy expression were cross‐validated in open‐access datasets. Conclusions: MST4, as an autophagy‐associated protein, plays a potential role in inducing cell death by increasing protein content in radiotherapy. [ABSTRACT FROM AUTHOR]