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167 results on '"Wang, Ya-Long"'

13. A novel route to synthesize B6O powder via reaction between CaB6 and B2O3.

Author

Wang, Ya‐Long, Yang, Xiao‐Hui, and Zhang, Guo‐Hua

Subjects
*SCANNING electron microscopes, *BORON oxide, *POWDERS, *BORIDES, *LEACHING
Abstract

A novel approach was applied to synthesize B6O using CaB6 and B2O3 powders as reactants. CaB6 and B2O3 were reacted to generate B6O and CaB2O4 at 1573 K, and the by‐product CaB2O4 was removed by acid leaching. It was found that the samples prepared in this work were oxygen deficient (B6Ox, x ≈.76–.77). The optimal molar ratio of CaB6 to B2O3 was determined to be 3:5, and excess B2O3 could not lead to a change in the value of oxygen occupancy. Scanning electron microscope images showed that regular holes similar to the morphologies of CaB6 particles were exhibited in the final samples, which could be explained by the diffusion of CaB6 during the reaction process. [ABSTRACT FROM AUTHOR]

Published
2025
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14. A novel route to synthesize B6O powder via reaction between CaB6 and B2O3.

Author

Wang, Ya‐Long, Yang, Xiao‐Hui, and Zhang, Guo‐Hua

Subjects
SCANNING electron microscopes, BORON oxide, POWDERS, BORIDES, LEACHING
Abstract

A novel approach was applied to synthesize B6O using CaB6 and B2O3 powders as reactants. CaB6 and B2O3 were reacted to generate B6O and CaB2O4 at 1573 K, and the by‐product CaB2O4 was removed by acid leaching. It was found that the samples prepared in this work were oxygen deficient (B6Ox, x ≈.76–.77). The optimal molar ratio of CaB6 to B2O3 was determined to be 3:5, and excess B2O3 could not lead to a change in the value of oxygen occupancy. Scanning electron microscope images showed that regular holes similar to the morphologies of CaB6 particles were exhibited in the final samples, which could be explained by the diffusion of CaB6 during the reaction process. [ABSTRACT FROM AUTHOR]

Published
2025
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18. Giant Pyramidal Near‐Infrared InP/ZnS Quantum Dots with Size Over 15 nm for Cell Imaging.

Author

Zhang, Wenda, Duan, Xijian, Tan, Yangzhi, Hao, Junjie, Zhu, Hongmei, Wang, Qingqian, Yang, Hongcheng, Liu, Haochen, Wang, Kai, Wang, Zhiwen, Wang, Ya‐Long, Song, Yujie, and Sun, Xiao Wei

Subjects
EPITAXY, CELL imaging, SURFACE defects, TISSUES, NUCLEATION
Abstract

In recent years, near‐infrared quantum dots (NIR QDs) have emerged as a promising candidate for biological imaging owing to their strong fluorescence penetrating into biological tissues and high imaging signal‐to‐noise ratio. Among various materials, InP QDs are environmentally friendly and have a relatively narrow bandgap of 1.35 eV, which provides a possibility for their emission wavelength to extend to the near‐infrared region. However, the strong reactivity of the precursor of phosphorus makes it challenging to synthesize NIR InP QDs, as it leads to rapid nucleation of the InP core. Herein, a method of epitaxial growth is reported to synthesize NIR InP QDs. Through high‐temperature nucleation and low‐temperature epitaxial growth, NIR InP QDs larger than 15 nm in size and with an emission wavelength of 807 nm are successfully synthesized. Furthermore, by removing InPOx defects on the surface of the core through HF etching, the quantum yield (QY) is increased from 6% to 12%. Ligand exchange successfully converted oil‐soluble ligands into water‐soluble ones, leading to excellent performance in cell imaging. The study provides a promising approach to the synthesis of desirable NIR InP QDs for use in biomedical imaging applications. [ABSTRACT FROM AUTHOR]

Published
2024
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27. Recent Progress of Activity-Based Fluorescent Probes for Imaging Leucine Aminopeptidase.

Author

Li, Ze-Jun, Wang, Cai-Yun, Xu, Liang, Zhang, Zhen-Yu, Tang, Ying-Hao, Qin, Tian-Yi, and Wang, Ya-Long

Subjects
FLUORESCENT probes, LEUCINE, LIVER cancer, BIOMARKERS, SMALL molecules
Abstract

Leucine aminopeptidase (LAP) is an important protease that can specifically hydrolyze Leucine residues. LAP occurs in microorganisms, plants, animals, and humans and is involved in a variety of physiological processes in the human body. In the physiological system, abnormal levels of LAP are associated with a variety of diseases and pathological processes, such as cancer and drug-induced liver injury; thus, LAP was chosen as the early biochemical marker for many physiological processes, including cancer. Considering the importance of LAP in physiological and pathological processes, it is critical that high-efficiency and dependable technology be developed to monitor LAP levels. Herein, we summarize the organic small molecule fluorescence/chemiluminescence probes used for LAP detection in recent years, which can image LAP in cancer, drug-induced liver injury (DILI), and bacteria. It can also reveal the role of LAP in tumors and differentiate the serum of cirrhotic, drug-induced liver injury and normal models. [ABSTRACT FROM AUTHOR]

Published
2023
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29. Progress of Dicyanomethylene-4H-Pyran Derivatives in Biological Sensing Based on ICT Effect

Author

Hou, Ting-Ting, Cai, Yi, Zhang, Zhen-Yu, Wang, Cai-Yun, Tang, Ying-Hao, Zhu, Ming-Qiang, and Wang, Ya-Long

Subjects
General Chemistry
Abstract

As one of the typical fluorescent cores, dicyanomethylene-4H-pyran (DCM) derivatives exhibit excellent photophysical and photochemical properties, such as large Stokes shift, excellent light stability, and tunable near-infrared (NIR) emission. The luminescence mechanism of DCM probes mainly depends on the intramolecular charge transfer (ICT). Hence, by regulating the ICT process, the probes can specifically act on the target molecule. Accordingly, a series of NIR DCM probes have been constructed to detect the ions, reactive oxygen species (ROS), and biological macromolecules in cells. However, there is no relevant review to summarize it at present. This minireview mainly summarizes the NIR DCM probes based on ICT effect and their applications in biosensors and biological imaging in recent years. This will be beneficial to innovatively construct new DCM probes and actively promote their application in the future.

Published
2022

38. Pachymic acid protects oocyte by improving the ovarian microenvironment in polycystic ovary syndrome mice†

Author

Fu, Xian-Pei, primary, Xu, Lin, additional, Fu, Bin-Bin, additional, Wei, Kang-Na, additional, Liu, Yu, additional, Liao, Bao-Qiong, additional, He, Shu-Wen, additional, Wang, Ya-Long, additional, Chen, Ming-Huang, additional, Lin, Yan-Hong, additional, Li, Fei-Ping, additional, Hong, Zi-Wei, additional, Huang, Xiao-Hua, additional, Xu, Chang-Long, additional, and Wang, Hai-Long, additional

Published
2020
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41. Design of multi - frequency constant current source based on intracellular and extracellular fluid capacity

Author

Xu Jia Wei, Wang Ya Long, Du Qiang, and Ke Li

Subjects
010302 applied physics, Battery (electricity), Current-feedback operational amplifier, Computer science, Focused Impedance Measurement, Feedback loop, Current source, 01 natural sciences, Characteristic impedance, 010305 fluids & plasmas, law.invention, Transmission (mechanics), Excitation current, law, 0103 physical sciences, Electronic engineering, Waveform, Output impedance, Current (fluid), Electrical impedance, Voltage
Abstract

Excitation current sources in multi-frequency detection systems for intracellular and extracellular fluid measurement, need to meet special requirements such as spectral width, waveform stability, phase synchronization and high output impedance. In this paper, the second generation of current transmitter AD844 as the core of the mirror image feedback current source was been designed, the theoretical analysis of the working principle and to improve and supplement, based on a current feedback operational amplifier and feedback loop technology, high precision low power voltage control Battery. Derive the transmission characteristics of the circuit, analyze the circuit output current and the equivalent output characteristic impedance. The load experiment shows that the load voltage waveform of the current source is consistent with the actual voltage waveform at 10kHz-1MHz frequency. The output current of the voltage control current source is constant and has a high output impedance, which meets the measurement experiment requirements, so this method can be regarded as an effective approach for ideal constant-current source.

Published
2018
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42. The effects of graphene quantum dots on the maturation of mouse oocytes and development of offspring

Author

Lin, Yan‐Hong, primary, Zhuang, Shu‐Xin, additional, Wang, Ya‐Long, additional, Lin, Sheng, additional, Hong, Zi‐Wei, additional, Liu, Yu, additional, Xu, Lin, additional, Li, Fei‐Ping, additional, Xu, Bai‐Hui, additional, Chen, Ming‐Huang, additional, He, Shu‐Wen, additional, Liao, Bao‐Qiong, additional, Fu, Xian‐Pei, additional, Jiang, Zhong‐Qing, additional, and Wang, Hai‐Long, additional

Published
2019
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47. SKAP2 regulates Arp2/3 complex for actin-mediated asymmetric cytokinesis by interacting with WAVE2 in mouse oocytes

Author

He, Shu-Wen, primary, Xu, Bai-Hui, additional, Liu, Yu, additional, Wang, Ya-Long, additional, Chen, Ming-Huang, additional, Xu, Lin, additional, Liao, Bao-Qiong, additional, Lui, Rui, additional, Li, Fei-Ping, additional, Lin, Yan-Hong, additional, Fu, Xian-Pei, additional, Fu, Bin-Bin, additional, Hong, Zi-Wei, additional, Liu, Yu-Xin, additional, Qi, Zhong-Quan, additional, and Wang, Hai-Long, additional

Published
2017
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48. AIE-Based Dynamic in SituNanoscale Visualization of Amyloid Fibrillation from Hen Egg White Lysozyme

Author

Fan, Cheng, Wang, Ya-Long, Zhao, Peng-Ju, Qu, Hong-Qing, Su, Yu-Xuan, Li, Chong, and Zhu, Ming-Qiang

Abstract

Protein misfolding and denaturation, represented by amyloid fibrillation, are associated with many diseases. However, as a general chemical biological process, the dynamic structure information on amyloid fibrillation has not been demonstrated categorically. Herein, hen egg white lysozyme (HEWL) was used as the model protein of interest to realize in situnanoscale imaging of protein fibrillation process using the fluorophores with aggregation-induced emission (AIE) activity. The AIE-active fluorophores exhibit the reversible capability of association and dissociation with β-sheet structure and thus dynamic binding-induced emission, which causes the spontaneous switching of fluorescence. The entire HEWL denaturation process induced by sodium dodecyl sulfate (SDS) at ambient conditions was demonstrated in detail by using two AIE-active fluorophores (TPE-NaSO3and PD-BZ-OH) through reversible electrostatic interaction and specific labeling between AIE probes and β-sheet structures of amyloid fibrils, respectively. The results indicate that PD-BZ-OH is more specific AIE probe for amyloid fibrils than TPE-NaSO3. In comparison, the SEM and TEM results show the same denaturation process of protein fibrillation induced by SDS at different concentrations. The static super-resolution imaging of amyloid fibrils is performed with a resolution of 35 nm using PD-BZ-OH aqueous solution without additional auxiliary conditions. The dynamic evolution process of HEWL amyloid fibrillation is in situvisualized through super-resolution fluorescent microscopy with nanoscale resolution. Both static and dynamic super-resolution imaging of amyloid fibrillation provides detailed nanoscale structure information exceeding 50 nm resolution, which is of great significance in the exploration of amyloid fibrillation and related diseases.

Published
2020
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49. Real-Time Fluorescence In SituVisualization of Latent Fingerprints Exceeding Level 3 Details Based on Aggregation-Induced Emission

Author

Wang, Ya-Long, Li, Chong, Qu, Hong-Qing, Fan, Cheng, Zhao, Peng-Ju, Tian, Rui, and Zhu, Ming-Qiang

Abstract

A water-soluble probe, TPA-1OH, with aggregation-induced emission activity is synthesized and used for expedient real-time fluorescence in situvisualization of latent fingerprints (LFPs). A TPA-1OH aqueous solution exhibits nonfluorescence in pure water while strong fluorescence upon molecular aggregation induced by addition of poor solvent. Fluorescence images of LFPs on a variety of substrates, including rough surfaces such as walls, bricks, and paper, are developed under 405 nm light, by soaking in or spraying with a TPA-1OH aqueous solution (30 μM) without any necessity of organic cosolvents and post-treatment steps. The probe is noncytotoxic at a concentration lower than 50 μM. The development process of LFPs is demonstrated by real-time fluorescence in situimaging. The exponential relationship between the relative fluorescence intensity and time is deduced from the fitting curve. The LFP images developed by TPA-1OH are evident and intact enough to allow that the level 1–3 details are displayed and analyzed. Noteworthily, the level 3 details of LFPs such as the fingerprint ridge width and the characteristics of the sweat pores are evidently visible under fluorescence microscopy. Even the nanoscopic details exceeding level 3 are visualized under super-resolution microscopy with sub-50 nm optical resolution.

Published
2020
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