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Supplemental material, sj-docx-1-cnr-10.1177_10547738221090556 for The Effect of Nursing Management of Patients Undergoing Interventional Therapy for Liver Cancer Compared with Standard Care on Patient-Reported Outcomes by Xiu-Bei Wang, Ling-Fang Sun, Mei-E Niu, Jian-Zheng Cai and Hai-Fang Wang in Clinical Nursing Research

To explore novel antitumor agents with high efficiency and low toxicity, riluzole alkyl derivatives (4a-4i) were synthesized. Their anti-proliferative activities against HeLa, HepG2, SP2/0, and MCF-7 cancer cell lines were assessed by the CCK-8 assay and compared with human normal liver (LO2) cells. Most of them showed potent cytotoxic effects against four human tumor cell lines and low toxic to LO2 cells. In particular, 2-(N-ethylamine)-6-trifluoromethoxy- benzothiazole (4a) showed a IC50 value of 7.76 μmol/L in HeLa cells and was found to be nontoxic to LO2 cells up to 65 μmol/L. Furthermore, flow cytometry indicated that 4a could induce remarkable early apoptosis and G2/M cell cycle arrest in HeLa cells. It also impaired the migration ability of HeLa cells in wound healing assays. Western blot results demonstrated that 4a suppressed Bcl-2 protein expression but increased the level of Bax in HeLa cells, and elevated the Bax/Bcl-2 expression ratio. These new findings suggest that 4a exhibited beneficially anti-cervical cancer effect on HeLa cells by inducing HeLa cell apoptosis.

To compare the difference of protein expression between the post-overwintering stage and the diapauses preparation stage inA quantitative proteomic analysis was performed inA total of 244 differentially expressed proteins were identified inThis is the first study to identify the overwintering diapause-related proteins in[

To investigate the seasonal fluctuations of mosquitoes in Taibai Lake area of Jining City, and evaluate the application effects of two mosquito trapping tools (Gongfu Xiaoshuai mosquito lamp and WJ-C mosquito sampler), so as to provide references for the effective surveillance, prevention and control of local mosquito vectors.The overnight capture of mosquitoes with a man-bait net trap, Gongfu Xiaoshuai mosquito lamp, and WJ-C mosquito sampler was performed to collect mosquitoes. The species of adult mosquitoes and seasonal fluctuations were investigated and analyzed.A total of 10 914 mosquitoes belonging to 13 species, 5 genera were collected with the overnight capture of mosquitoes with the man-bait net trap, andThe mosquito species are varied in Taibai Lake area of Jining City. Therefore, monitoring should be strengthened. In addition, the two mosquito trapping tools are sensitive, but they have both advantages and disadvantages, thus we should better pay attention to the consistency of monitoring methods in use.[

To explore the characteristics of gene sequence of mtDNA-COⅠ ofAdult mosquitoes were collected from Jinan, Jining, Qingdao cities and other places in Shandong Province. The sensitive, dichlorvos-resistant, pyrethroid-resistant and propoxur-resistant strains were reared in the lab. Five species of mosquito (The amplified mtDNA-COⅠfragments ofmtDNA-COⅠcould not serve as the molecular marker to analyze the population genetic variation and phylogenesis of

To investigate the species, density and distribution of the overwintering adult mosquitoes in Taibaihu District, Jining City.The overwintering adult mosquitoes were monitored by visual observation in Taibaihu District, Jining City from December 2015 to March 2016. The mosquitoes were collected and dissected to observe the body fat accumulation and ovarian development situation.Totally 1 677 mosquitoes were captured and all of them wereThe adults of

The single atom thick sp 2 carbon structure of graphene gives rise to its unique properties and potential applications. However, one serious obstacle for its application is that graphene is prone to aggregate in suspension and gradually stack into graphite. Here, we report a novel approach to solve this problem. The basic idea is to introduce sp 2 carbon nano-islands on the graphene sheets that act as permanent ripples to prevent the stacking and graphitization of graphene and make it easy to re-suspend. Unlike most functionalization methods, this approach avoids the introduction of heteroatoms. Thus, it does not deteriorate the structure and change the properties of graphene. The carbon-rippled graphene has a remarkable electronic conductivity of ~65000 S·m - 1 , and can be readily suspended in solvent.

Tissue culture lab is a place of culturing vaccination materials in the process of breeding. Measurement and control of temperature, humidity and illumination is the essential condition. At present, exist many problems in measurement and control system, such as the low controlling precision, mutual interference between temperature and humidity controlling, energy waste. In addition, the data of experimentation could not be measured, recorded, stored and handled. The price of foreign product is so expensive that general units can’t accept it. In order to solve these problems, measurement and control of temperature and humidity was studied to develop more applicable multi parameter measure and control system with low price and stable performance, so that the temperature, humidity and illumination indicator can be automatically measured and controlled. In this article, according to status quo of tissue culture lab and requirement of temperature and humidity control and system function, the system overall structure was built, The system working process, characteristic and main technical indicator were introduced.

Distributed video coding has received much attention in recent years. It shifts the complex motion estimation from the encoder to the decoder side, thus makes low-complexity encoding a reality. Among some motion estimation methods exploited for DVC, expectation maximization (EM) algorithm is the most effective. However, the full searching involved in EM algorithm makes it complex. So, in this paper, we adopt a diamond searching instead of the full searching to optimize the motion searching. The simulation results show that the proposed diamond searching saves time while with the almost same rate-distortion quality compared to the current EM algorithm.